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Russell C Callaghan, Jodi M Gatley, Jenna Sykes, Lawren Taylor
INTRODUCTION AND AIMS: Even though individuals with substance-use disorders have a high prevalence of tobacco smoking, surprisingly little is known about smoking-related mortality in these populations. The current retrospective cohort study aims to address this gap. DESIGN AND METHODS: The study sample included cohorts of individuals hospitalised in California between 1990 and 2005 with alcohol- (n = 509 422), cocaine- (n = 35 276), opioid- (n = 53 172), marijuana- (n = 15 995) or methamphetamine-use (n = 36 717) disorders...
December 23, 2016: Drug and Alcohol Review
C Hedén Ståhl, M Lind, A-M Svensson, S Gudbjörnsdottir, A Mårtensson, A Rosengren
OBJECTIVE: To estimate the excess risk of stroke in relation to glycaemic control in patients with type 1 diabetes. METHODS: In this prospective, matched cohort study, we identified patients with type 1 diabetes, aged ≥18 years, who were registered in the Swedish National Diabetes Register from 1998-2011 and five control subjects for each case from the general population, matched for age, sex and county of residence. The risks of all strokes, ischaemic stroke and haemorrhagic stroke were estimated using Cox hazard regression...
December 7, 2016: Journal of Internal Medicine
Luca Evangelisti, Lorenzo Spada, Weixing Li, Susana Blanco, Juan Carlos López, Alberto Lesarri, Jens-Uwe Grabow, Walther Caminati
Upon supersonic expansion, formic acid and cyclobutanone (CBU) form a molecular cluster in which the two constituent molecules, linked by OHO and CHO hydrogen bonds, undergo a rapid interconversion between two equivalent forms. The tunneling motion takes place through the rupture and reformation of the C-HO hydrogen bond between the carbonyl oxygen of HCOOH and one of the two hydrogen atoms of the methylenic group adjacent to the cyclobutanone keto group. From the microwave spectra, tunneling energy splittings (ΔE01) have been determined for the parent (1122...
December 21, 2016: Physical Chemistry Chemical Physics: PCCP
Geertruida Slinger, Michel R T Sinke, Kees P J Braun, Willem M Otte
OBJECTIVE: Since the introduction of diffusion tensor imaging, white matter abnormalities in epilepsy have been studied extensively. However, the affected areas reported, the extent of abnormalities and the association with relevant clinical parameters are highly variable. We aimed to obtain a more consistent estimate of white matter abnormalities and their association with clinical parameters in different epilepsy types. METHODS: We systematically searched for differences in white matter fractional anisotropy and mean diffusivity, at regional and voxel level, between people with epilepsy and healthy controls...
2016: NeuroImage: Clinical
Huihui Li, Sukhwinder Singh, Sridhar Bhavani, Ravi P Singh, Deepmala Sehgal, Bhoja R Basnet, Prashant Vikram, Juan Burgueno-Ferreira, Julio Huerta-Espino
Rusts, a fungal disease as old as its host plant wheat, has caused havoc for over 8000 years. As the rust pathogens can evolve into new virulent races which quickly defeat the resistance that primarily rely on race specificity, adult plant resistance (APR) has often been found to be race non-specific and hence is considered to be a more reliable and durable strategy to combat this malady. Over decades sets of donor lines have been identified at International Maize and Wheat Improvement Center (CIMMYT) representing a wide range of APR sources in wheat...
2016: Frontiers in Plant Science
Louisdon Pierre, Adebayo Adeyinka, Keneisha Bailey
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
Yacob G Tedla, Yuichiro Yano, Mercedes Carnethon, Philip Greenland
Experimental studies conducted on animal and human endothelium suggested that higher systolic blood pressure (SBP) variability reduces bioavailability of nitric oxide and increases vascular smooth muscle cell proliferation. These vascular wall changes could stiffen the arterial wall. Using data from the Multiethnic Study of Atherosclerosis, we investigated the association between long-term SBP variability and 10-year percent change in arterial stiffness among 1122 individuals (mean age 57 years, 46% males at baseline) who were not taking antihypertensive medications...
January 2017: Hypertension
Pan Jiang, Qiurong Lv, Tianwen Lai, Feng Xu
Hypomagnesemia is commonly seen but frequently overlooked in critically ill patients in intensive care unit (ICU). However, the strength and consistency of the effect of hypomagnesemia on outcomes in critically ill patients remain controversial. In this report, we performed a systematic review and meta-analysis to evaluate the association of serum magnesium level with prognosis of critically ill patients upon admission to the ICU. A comprehensive search for clinical trials was performed, and ten studies comprising 1122 cases and 630 controls were finally selected for analysis...
October 6, 2016: Shock
A Cicchetti, T Rancati, M Ebert, C Fiorino, F Palorini, A Kennedy, D J Joseph, J W Denham, V Vavassori, G Fellin, B Avuzzi, C Stucchi, R Valdagni
AIM: To investigate late gastrointestinal toxicity in a large pooled population of prostate cancer patients treated with radical radiotherapy. Normal tissue complication probability models were developed for late stool frequency and late rectal pain. METHODS AND MATERIALS: Population included 1336 patients, 3-year minimum follow-up, treated with 66-80Gy. Toxicity was scored with LENT-SOMA-scale. Two toxicity endpoints were considered: grade ⩾2 rectal pain and mean grade (average score during follow-up) in stool frequency >1...
December 2016: Physica Medica: PM
Fashen Chen, Xiaohe Liu, Zhian Zhang, Ning Zhang, Anqiang Pan, Shuquan Liang, Renzhi Ma
Urchin-like cobalt oxide (Co3O4) hollow spheres can be successfully prepared by thermal decomposition of cobalt carbonate hydroxide hydrate (Co(CO3)0.5(OH)·0.11H2O) obtained by template-assisted hydrothermal synthesis. The morphology, crystal structure evolution and thermal decomposition behaviors of the as-prepared products have been carefully investigated. A plausible formation mechanism of the urchin-like Co3O4 hollow spheres in the presence of hexadecyl trimethyl ammonium bromide (CTAB) as the surfactant template is proposed...
September 27, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
N R Aimée, A J van Wijk, M Maltz, M M Varjão, H D Mestrinho, J C Carvalho
OBJECTIVE: This study aimed to assess the extent to which dental caries and fluorosis, in addition to sociodemographic and oral health behavior determinants, impact the oral health-related quality of life (OHRQoL) of adolescents. METHODS: All adolescents attending from sixth to eighth grades in the Region of Itapoã, Federal District of Brazil (n = 1122), were screened, and 618 10-15-year-olds were selected. Parents answered a questionnaire about their family's socioeconomic status...
September 27, 2016: Clinical Oral Investigations
Maral DerSarkissian, Yongling Xiao, Mei Sheng Duh, Patrick Lefebvre, Andrine R Swensen, Christopher F Bell
BACKGROUND: Benign prostatic hyperplasia (BPH) is a common disease in men that is characterized by lower urinary tract symptoms. Pharmacologic treatment with alpha blockers (ABs) and 5-alpha reductase inhibitors (5ARIs) is recommended to alleviate symptoms, prevent disease progression that can lead to complications, and reduce health care costs. OBJECTIVE: To compare clinical, economic, and health care resource utilization outcomes among BPH patients treated with early continuous combination AB and 5ARI therapy (dutasteride vs...
October 2016: Journal of Managed Care & Specialty Pharmacy
Ye Sun, Yaqiang Duan, Liang Hao, Zipeng Xing, Ying Dai, Rui Li, Jinlong Zou
The low electrocatalytic activity for oxygen reduction reaction (ORR) and the high cost of cathode catalyst in microbial fuel cells (MFCs) are the important factors that limit the practical applications. The metal-free nitrogen (N)-doped partly graphitized carbon (NPGC) as cathode catalyst is prepared at different temperatures (700-1050 °C) by using waste cornstalks as the carbon source and melamine as the N source. Scanning electron microscopy, X-ray diffraction, specific surface areas, and transmission electron microscopy have been used, in parallel with electrochemical activity tests including rotating disk electrode (RDE) and power output, to clarify how the active constituents and structure of NPGC influence the MFCs performance...
October 5, 2016: ACS Applied Materials & Interfaces
Tomi E Mäki-Opas, Katja Borodulin, Heli Valkeinen, Sari Stenholm, Anton E Kunst, Thomas Abel, Tommi Härkänen, Leena Kopperoinen, Pekka Itkonen, Ritva Prättälä, Sakari Karvonen, Seppo Koskinen
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Yajun Jiang, Dexing Yang, Yuan Yuan, Jian Xu, Dong Li, Jianlin Zhao
A novel method for simultaneous measurement of strain and high temperature using a Type II fiber Bragg grating (FBG) and a miniature fiber Fabry-Perot interferometer (MFFPI) is proposed. The MFFPI is produced by fusion splicing a short section of quartz capillary tube with two single-mode fibers, and then it is exposed by a focused femtosecond laser and a phase mask to inscribe a Type II FBG nearby. The reflection spectrum of this sensor is the superposition of the reflection spectrum of the FBG and the interference fringe of the MFFPI...
August 10, 2016: Applied Optics
Frank Stegemann, Oliver Janka
During phase analytical investigations in the rare-earth element rich side of the ternary system cerium-gold-aluminum, the new ternary rare-earth (RE) gold aluminides with a composition of RE16AuxAl13-x (RE = La-Nd, Sm, x≤ 3.37) have been synthesized first by reactive eutectics of RE/Au with Al. Single crystals of high quality can be obtained by this method. The title compounds can be selectively prepared by annealing arc-melted beads of appropriate composition below the peritectic point of the respective system...
September 21, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
A Imaz, J Niubó, A D Kashuba, E Ferrer, C Sykes, N Rozas, L Acerete, A Vila, D Podzamczer
OBJECTIVES: The aim of the study was to quantify elvitegravir (EVG) concentrations in the semen of HIV-1-infected men receiving antiretroviral therapy (ART) consisting of an elvitegravir/cobicistat/emtricitabine/tenofovir (EVG/COBI/FTC/TDF) single-tablet regimen. METHODS: A phase IV, cross-sectional study was carried out including HIV-1-infected male adults with suppressed plasma HIV-1 RNA who switched ART to EVG/COBI/FTC/TDF. Total EVG concentrations at the end of the dosing interval (C24 h ) and HIV-1 RNA were measured in paired seminal plasma (SP) and blood plasma (BP) samples 4 weeks after switching to EVG/COBI/FTC/TDF...
August 1, 2016: HIV Medicine
Manlio Cipriani, Maurizio Lunati, Maurizio Landolina, Alessandro Proclemer, Giuseppe Boriani, Renato P Ricci, Roberto Rordorf, Maria Vittoria Matassini, Luigi Padeletti, Saverio Iacopino, Giulio Molon, Giovanni B Perego, Maurizio Gasparini
AIM: Mitral regurgitation (MR) is a common finding in patients with heart failure with debatable effects on prognosis. Reduction in MR is one of the mechanisms by which cardiac resynchronization therapy (CRT) exerts its beneficial effects. We investigated the prognostic impact of baseline MR and MR persistence after CRT on outcomes of treated patients. METHODS AND RESULTS: We prospectively followed 1122 CRT patients (66.4 ± 10.3 years, 78% male) who were stratified according to baseline MR severity as having MR- (degree 0-1; n = 508, 45%) or MR+ (degrees 2-3-4; n = 614, 55%)...
August 2016: European Journal of Heart Failure
Dingxie Liu
The associations of estrogen receptor (ER) and progesterone receptor (PR) pathways with the prognosis of colorectal cancer (CRC) are still controversial. The aim of this study was to readdress these issues by introducing a gene signature-based approach to semiquantitate pathway activity. In this approach, the ER and PR pathway activities in CRC were computed based on the expression profiles of the signature genes of ER and PR pathways, respectively. The results showed that the ER pathway activity was progressively significantly decreased from normal colorectal mucosa, colorectal adenoma to CRC...
August 2016: FEBS Journal
Seon-Cheol Park, Min-Soo Lee, Sang Woo Hahn, Tian-Mei Si, Shigenobu Kanba, Mian-Yoon Chong, Chee Kok Yoon, Pichet Udomratn, Adarsh Tripathi, Norman Sartorius, Naotaka Shinfuku, Margarita M Maramis, Yong Chon Park
OBJECTIVE: Using data from the Research on Asian Psychotropic Prescription Patterns for Antidepressants (REAP-AD) study, we aimed to present the rates and clinical correlates of suicidal thoughts/acts in patients recruited from a total of 40 centres in 10 Asian countries/areas: China, Hong Kong, India, Indonesia, Japan, Korea, Malaysia, Singapore, Taiwan, and Thailand. METHODS: Data from 1122 patients with depressive disorders in the REAP-AD study were used. The ICD-10 was employed to diagnose depressive episodes and recurrent depressive disorder...
December 2016: Acta Neuropsychiatrica
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