Read by QxMD icon Read


Debbie L Croyden, Helen A Vidgen, Emma Esdaile, Emely Hernandez, Anthea Magarey, Carly J Moores, Lynne Daniels
BACKGROUND: PEACH™QLD translated the PEACH™ Program, designed to manage overweight/obesity in primary school-aged children, from efficacious RCT and small scale community trial to a larger state-wide program. This paper describes the lessons learnt when upscaling to universal health coverage. METHODS: The 6-month, family-focussed program was delivered in Queensland, Australia from 2013 to 2016. Its implementation was planned by researchers who developed the program and conducted the RCT, and experienced project managers and practitioners across the health continuum...
March 13, 2018: BMC Public Health
Dawen Gao, Yu Tao, Yuan Fu, Hong Liang
Microbial biofilms are multicellular communities of sessile microorganisms encased by the hydrated polymeric matrix. They have significant influences on both aquatic/terrestrial ecosystem and anthropogenic activities. Taking advantage of the governing features of selective stress (Tan and Ng in Water Res 42:1122-1132, 2008; Wei in Water Res 45:863-871, 2011; Dereli in Water Res 59C:11-22, 2014), the evenness of microbial communities in a membrane-centered mesocosm was successfully manipulated. By measuring the biofilm growing rates under different evenness levels of communities, an evenly distributed community favors the formation of biofilms was observed...
March 8, 2018: Microbial Ecology
Asger Granfeldt, Mads Wissenberg, Steen Møller Hansen, Freddy K Lippert, Christian Torp-Pedersen, Søren Helbo Skaarup, Lars W Andersen, Erika Frischknecht Christensen, Christian Fynbo Christiansen
INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is associated with a non-shockable rhythm as presenting rhythm in out-of-hospital cardiac arrest (OHCA). Whether the severity of the underlying disease is related to presenting rhythm is unknown. We hypothesize that increased severity of COPD in OHCA patients is associated with an increased prevalence of non-shockable rhythm. METHODS: This study included OHCA patients ≥40 years from the Danish Cardiac Arrest Registry (2001-2014)...
March 5, 2018: Resuscitation
Patrick O Richard, Ardalan E Ahmad, Shaheena Bashir, Alexandre Zlotta, Bimal Bhindi, Ricardo Leao, Madhur Nayan, Aza Mohammed, Neil E Fleshner, Girish S Kulkarni
INTRODUCTION: Non-muscle invasive bladder cancer (NMIBC) accounts for 75-85% of all bladder cancers (UBC). Many UBC patients are also afflicted by diabetes mellitus (DM). It has been postulated that several oral hypoglycemic agents could impact disease-specific survival (DSS), but the data are sparse among NMIBC patients. Our primary objective was to evaluate the impact of metformin on DSS and overall survival (OS) in NMIBC patients. METHODS: This is a retrospective, population-based study that used linked administrative databases to identify diabetic patients ≥66 years who were subsequently diagnosed with NMIBC in Ontario, between 1992 and 2012...
February 23, 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
Hyo-Joon Yang, Min-Jung Kwon, Yoosoo Chang, Seul-Ki Song, Kwang-Sung Ahn, Han-Na Kim, Yeojun Yun, Hyung-Lae Kim, Dong Il Park
GOALS AND BACKGROUND: This study aimed to compare differences in the fecal microbiota according to the risk of advanced colorectal neoplasia (ACN) based on a risk-score model in a large Korean cohort. STUDY: Stool samples were collected from 1122 health screening recipients: 404 enrolled in the average risk (AR) group, 514 in the moderate risk (MR) group, and 204 in the high risk (HR) group, in accordance with their risk of ACN. The fecal microbiota was characterized using pyrosequencing of the V3-V4 region of the 16S rRNA genes...
February 9, 2018: Journal of Clinical Gastroenterology
Sajad Jamalpour, Shamsul Mohd Zain, Maryam Mosavat, Zahurin Mohamed, Siti Zawiah Omar
BACKGROUND: Although the influence of a common variant in the glucokinase regulatory gene (GCKR rs780094) in type 2 diabetes mellitus has been well documented, less data however, is available of its role in gestational diabetes mellitus (GDM). We carried out a case control study to assess the association between GCKR rs780094 and GDM in the Asian, and also a meta-analysis to further assess the strength of the association. METHODS: Demographic, clinical and genotype data were determined for 1122 women (267 cases and 855 controls) recruited from the University of Malaya Medical Centre in the Klang Valley, Kuala Lumpur...
January 30, 2018: Gene
Roman G Kuperman, Ronald T Checkai, Michael Simini, Geoffrey I Sunahara, Jalal Hawari
Individual effects of nitrogen-based energetic materials (EMs) 2,4-dinitrotoluene (2,4-DNT), 2-amino-4,6-dinitrotoluene (2-ADNT), 4-amino-2,6-dinitrotoluene (4-ADNT), nitroglycerin (NG), and 2,4,6,8,10,12-hexanitrohexaazaisowurtzitane (CL-20) on litter decomposition, an essential biologically-mediated soil process, were assessed using Orchard grass (Dactylis glomerata) straw in Sassafras sandy loam (SSL) soil, which has physicochemical characteristics that support "very high" qualitative relative bioavailability for organic chemicals...
February 1, 2018: Ecotoxicology and Environmental Safety
Marion J Torres, Jean-Marc Sabate, Michel Bouchoucha, Camille Buscail, Serge Hercberg, Chantal Julia
Introduction: Diet plays an important role for patients with irritable bowel syndrome (IBS). The aim of this study was to compare the diets in terms of food consumption and nutrient intake between subjects with IBS and controls in a large French population. Methods: This study included 36,448 subjects from the Nutrinet-Santé cohort study, who completed a questionnaire pertaining to functional bowel disorders based on the Rome III criteria. Dietary data were obtained from at least three self-administered 24 h records via the internet...
2018: Therapeutic Advances in Gastroenterology
Deborah R Smith, R F G J King, L C Duckworth, L Sutton, T Preston, J P O'Hara, B Jones
Criterion data for total energy expenditure (TEE) in elite rugby are lacking, which prediction equations may not reflect accurately. This study quantified TEE of 27 elite male rugby league (RL) and rugby union (RU) players (U16, U20, U24 age groups) during a 14-day in-season period using doubly labelled water (DLW). Measured TEE was also compared to estimated, using prediction equations. Resting metabolic rate (RMR) was measured using indirect calorimetry, and physical activity level (PAL) estimated (TEE:RMR)...
January 20, 2018: European Journal of Applied Physiology
Lei Tan, Xinhai Li, Zhixing Wang, Huajun Guo, Jiexi Wang
The further development of lithium-sulfur (Li-S) batteries is limited by the fact that the soluble polysulfide leads to the shuttle effect, thereby reducing the cycle stability and cycle life of the batteries. To address this issue, here a thin and lightweight (8 μm and 0.24 mg cm-2) reduced graphene oxide@MoS2 (rGO@MoS2) interlayer between the cathode and the commercial separator is developed as a polysulfide barrier. The rGO plays the roles of both a polysulfide physical barrier and an additional current collector, while MoS2 has a high chemical adsorption for polysulfides...
January 16, 2018: ACS Applied Materials & Interfaces
Anderson B Leite, Caroline Saucier, Eder C Lima, Glaydson S Dos Reis, Cibele S Umpierres, Beatris L Mello, Mohammad Shirmardi, Silvio L P Dias, Carlos H Sampaio
In this study, avocado seed was successfully used as raw material for producing activated carbons by conventional pyrolysis. In order to determine the best condition to produce the activated carbons, a 22 full-factorial design of experiment (DOE) with three central points was employed by varying the temperature and time of pyrolysis. The two evaluated factors (temperature and time of pyrolysis) strongly influenced the SBET, pore volumes, hydrophobicity-hydrophilicity ratio (HI) and functional groups values; both factors had a negative effect over SBET, pore volumes and functional groups which means that increasing the values of factors leads to decrease of these responses; on the other hand, with regards to HI, both factors caused a positive effect which means that increasing their values, the HI has an enhancement over its values...
December 28, 2017: Environmental Science and Pollution Research International
Jennifer L Beebe-Dimmer, Cecilia Yee, Electra Paskett, Ann G Schwartz, Dorothy Lane, Nynikka R A Palmer, Cathryn H Bock, Rami Nassir, Michael S Simon
BACKGROUND: Evidence suggests that risk of colorectal and prostate cancer is increased among those with a family history of the same disease, particularly among first-degree relatives. However, the aggregation of colorectal and prostate cancer within families has not been well investigated. METHODS: Analyses were conducted among participants of the Women's Health Initiative (WHI) observational cohort, free of cancer at the baseline examination. Subjects were followed for colorectal cancer through August 31st, 2009...
December 13, 2017: BMC Cancer
Natalia Khalaf, Chen Yuan, Tsuyoshi Hamada, Yin Cao, Ana Babic, Vicente Morales-Oyarvide, Peter Kraft, Kimmie Ng, Edward Giovannucci, Shuji Ogino, Meir Stampfer, Barbara B Cochrane, JoAnn E Manson, Clary B Clish, Andrew T Chan, Charles S Fuchs, Brian M Wolpin
BACKGROUND & AIMS: Use of aspirin and/or non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) reduces the risk of several cancers, but it is not clear if use of these drugs is associated with risk of pancreatic cancer. METHODS: We evaluated aspirin and non-aspirin NSAID use and risk of pancreatic adenocarcinoma in 141,940 participants from the Health Professionals Follow-up Study and Nurses' Health Study using multivariable-adjusted Cox proportional hazards regression...
December 8, 2017: Gastroenterology
Osbourne Quaye, Precious Cramer, Mark Ofosuhene, Laud K N Okine, Alexander K Nyarko
Extracts of Desmodium adscendens (Sw) DC are used for the treatment of various diseases but limited toxicological evaluations have been done on the medicinal plant. This study investigates toxicity effects of the leave extract of D adscendens, and the possibility of drug-drug interaction of the plant extract when co-administered with other drugs. Oral administrations of leaf extract of D adscendens to white Wistar rats in an acute toxicity studies allowed the estimation of an LD50 (median lethal dose) value of 1122 mg/kg body weight...
October 2017: Journal of Evidence-based Complementary & Alternative Medicine
Stephanie A Hooker, Jennalee S Wooldridge, Kaile M Ross, Kevin S Masters
PURPOSE: To examine the effects of an employer-based monetary incentive program on membership termination and usage at a fitness center. DESIGN: Retrospective nested case-control study examining the relationship between participation in an incentive program, visits to the fitness center, and membership termination at 1 year. SETTING: University-based fitness center. PARTICIPANTS: Members (N = 1122) of a university-based fitness center...
March 2018: American Journal of Health Promotion: AJHP
A Bantsar, P Colautti, V Conte, G Hilgers, M Pietrzak, S Pszona, H Rabus, A Selva
Nanodosimetry is a branch of dosimetry for investigation and modeling of the interaction pattern of ionizing radiation in nanometre site-sizes (at unit density), which dates back to the 1970's (Pszona S. A track ion counter. Proceedings of Fifth Symposium on Microdosimetry EUR 5452 d-e-f, Published by the Commission of the European Communities, Luxemburg, pp. 1107-1122 (1976)). To date, the different experimental approaches have lead to developing of three fully functional nanodosimeters: the Jet Counter operated at NCBJ, the Ion Counter operated at PTB and Startrack Counter operated at INFN-LNL...
November 29, 2017: Radiation Protection Dosimetry
Kristin Blom, Amir I Elshafie, Ulla-Britt Jönsson, Johan Rönnelid, Lena Douhan Håkansson, Per Venge
Visceral leishmaniasis (VL) is the most severe form of leishmaniasis. Recent findings indicate that dendritic cells have a key role in the defense against the Leishmania parasite and that the activity of this cell may be modified by the eosinophil secretory protein eosinophil-derived neurotoxin (EDN). We hypothesized that the interactions between dendritic cells and EDN might be of importance in the disease development. Cellular content of EDN was analyzed by ELISA. The single-nucleotide polymorphisms at positions 405, 416, and 1122 in the EDN gene were analyzed by real-time PCR with TaqMan® reagents...
January 2018: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
Bo-Wen Qin, Ke-Cheng Huang, Yu Zhang, Lei Zhou, Zheng Cui, Kuo Zhang, Xiao-Ying Zhang, Jing-Ping Zhang
Polymetallic complexes with interesting multifunctions have attracted extensive investigation. Synthesized through the use of different cobalt salt anions and solvents, five complexes, namely [CoII 4 CoIII 3 (H2 L)3 Cl5 (MeOH)] (1), [CoII 4 CoIII 3 (H2 L)3 (CH3 COO)4 (HCOO)⋅H2 O]n (2), [CoII 4 CoIII 3 (H2 L)3 (HCOO)4 (NO3 )⋅2H2 O]n (3), [CoII 4 CoIII 3 (H2 L)3 (bda)(CH3 COO)4 ⋅2H2 O]n (4), and [CoII 4 CoIII 3 (H2 L)3 (ipa)(HCOO)3 (dmf)⋅H2 O]n (5) (H6 L=bis-tris propane; BDA=biphenyl-4,4'-dicarboxylic acid; IPA=isophthalic acid; DMF=N,N-dimethylformamide), based on the heptanuclear {CoII 4 CoIII 3 } cluster with structures from 0D to 3D metal-organic frameworks (MOFs) have been solvothermally synthesized...
February 6, 2018: Chemistry: a European Journal
Gentaro Kumagai, Kanichiro Wada, Toshihiro Tanaka, Hitoshi Kudo, Toru Asari, Daisuke Chiba, Seiya Ota, Shigeyuki Nakaji, Yasuyuki Ishibashi
BACKGROUND: Studies have reported associations between neck pain and degenerative changes in the cervical spine in women, and between neck pain and obesity or metabolic syndrome. The present study investigated associations between neck pain or stiffness and lipid profiles in subjects recruited from the general population of a Japanese community. METHODS: The 1122 volunteers who participated in this study included 426 men (age 52.6 ± 15.5 years; body mass index 23...
November 22, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
Ik-Soo Lee, Seung-Hyun Jung, Jin Sook Kim
To identify active compounds in the roots of Euphorbia pekinensis for treatment of diabetic complications, an active column fraction from a 70% EtOH extract of E. pekinensis root was purified by preparative reversed-phase high-performance liquid chromatography, leading to the isolation of a new ellagic acid derivative, 3,3'-di-O-methylellagic acid 4-O-(6"-O-galloyl)-β-D-galactopyranoside (1), along with three known compounds, geraniin (2), 3,3'-di-O-methylellagic acid 4-O-β-D-xylopyranoside (3), and ellagic acid 3,3'-dimethyl ether (4)...
November 17, 2017: Planta Medica
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"