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Seize the day

Susan L Garber
Every day, in clinics and hospitals around the world, occupational therapists care for patients with serious problems requiring viable solutions. Each patient is unique, and his or her problem does not necessarily correspond to existing practice models. Practitioners must adapt standard approaches to provide effective outcomes, yet problems exist for which few or no beneficial approaches have been identified. Such clinical issues require solutions to be generated de novo from the practitioner's body of knowledge and past experience...
November 2016: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
Sofia-Ioanna Tseferidi, Fay Griva, Fotios Anagnostopoulos
The present study examined associations of time perspective (TP) with indicators of well-being including satisfaction with life, anxiety and depression, after controlling for sociodemographic factors. Adult participants (N = 413) completed a web-based questionnaire that included a short version of the Zimbardo Time Perspective Inventory, the State-Trait Anxiety Inventory, and the Center for Epidemiologic Studies-Depression Scale. Life satisfaction was more strongly associated with the present hedonistic dimension, suggesting that the tendency to take risks and to fulfil one's desires may lead to experiencing pleasure in a 'seize the day' approach to life...
August 25, 2016: Psychology, Health & Medicine
Pamela Cabarcos, Paloma Herbello-Hermelo, Iván Álvarez-Freire, Antonio Moreda-Piñeiro, María Jesús Tabernero, Ana María Bermejo, Pilar Bermejo-Barrera
A simple sample pre-treatment method based on solid phase microextraction (SPME) and gas chromatography-mass spectrometry (GC-MS) has been optimized and validated for the assessment of 15 residual solvents (2-propanol, 2-methylpentane, 3-methylpentane, acetone, ethyl acetate, benzene, hexane, methylcyclohexane, methylcyclopentane, m-xylene, propyl acetate, toluene, 1,2,4-trimethylbenzene, dichloromethane, and ethylbenzene) in seized illicit cocaine and heroin. DMSO and DMF as sample diluents were found to offer the best residual solvent transference to the head space for further adsorption onto the SPME fiber, and the developed method therefore showed high sensitivity and analytical recovery...
September 2016: Analytical and Bioanalytical Chemistry
Walid Albanna, Catharina Conzen, Miriam Weiss, Hans Clusmann, Matthias Fuest, Marguerite Mueller, Marc Alexander Brockmann, Walthard Vilser, Arno Schmidt-Trucksäss, Anke Hoellig, Marcel Seiz, Claudius Thomé, Konstantin Kotliar, Gerrit Alexander Schubert
BACKGROUND: Timely detection of impending delayed cerebral ischemia after subarachnoid hemorrhage (SAH) is essential to improve outcome, but poses a diagnostic challenge. Retinal vessels as an embryological part of the intracranial vasculature are easily accessible for analysis and may hold the key to a new and non-invasive monitoring technique. This investigation aims to determine the feasibility of standardized retinal vessel analysis (RVA) in the context of SAH. METHODS: In a prospective pilot study, we performed RVA in six patients awake and cooperative with SAH in the acute phase (day 2-14) and eight patients at the time of follow-up (mean 4...
2016: PloS One
Suzanne Martin Stricklin
BACKGROUND: Twenty-five percent of American adults experience a diagnosable psychiatric mental health (PMH) problem each year, and acute care medical-surgical nurses carry on average a five- to six-patient load per shift. Traditionally, U.S. PMH clinical experiences have occurred on inpatient units located within acute care hospitals or psychiatric hospital settings. However, many nursing programs are moving much of the PMH clinical experience to community-based settings. OBJECTIVES: This study aims to investigate how prelicensure undergraduate baccalaureate (BSN) student nurses and their faculty perceive students' ability to achieve learning outcomes in community-based PMH clinical settings...
July 2016: Journal of the American Psychiatric Nurses Association
Anne C Ritter, Candace M Kammerer, Maria M Brooks, Yvette P Conley, Amy K Wagner
OBJECTIVE: Posttraumatic seizures (PTS) commonly occur following severe traumatic brain injury (sTBI). Risk factors for PTS have been identified, but variability in who develops PTS remains. Excitotoxicity may influence epileptogenesis following sTBI. Glutamate transporters manage glutamate levels and excitatory neurotransmission, and they have been associated with both epilepsy and TBI. Therefore, we aimed to determine if genetic variation in neuronal glutamate transporter genes is associated with accelerated epileptogenesis and increased PTS risk after sTBI...
June 2016: Epilepsia
Veniero Gambaro, Gabriella Roda, Giacomo Luca Visconti, Sebastiano Arnoldi, Eleonora Casagni, Lucia Dell'Acqua, Fiorenza Farè, Eleonora Paladino, Chiara Rusconi, Stefania Arioli, Diego Mora
The taxonomic identification of the biological material contained in the hallucinogenic mushrooms culture media, was carried out using a DNA-based approach, thus highlighting the usefulness of this approach in the forensic identification of illegal samples also when they are present as basidiospores mixed in culture media and spore-bearing fruiting body are not present. This approach is very useful as it allows the unequivocal identification of potentially illicit material before the cultivation and it enables to stop the material to the Customs and to destroy it due to its dangerousness without cultivating the "grow-kits" and without instructing a criminal case...
June 5, 2016: Journal of Pharmaceutical and Biomedical Analysis
John W Williams, Gary Maslow
No abstract text is available yet for this article.
March 1, 2016: Annals of Internal Medicine
Javier A Muñiz, Gimena Gomez, Betina González, María Celeste Rivero-Echeto, Jean Lud Cadet, Edgar García-Rill, Francisco J Urbano, Veronica Bisagno
Caffeine is the world's most popular psychoactive drug and is also an active adulterant found in many drugs of abuse, including seized cocaine samples. Despite several studies which examine the effects of caffeine or cocaine administered as single agents, little data are available for these agents when given in combination. The purpose of the present study was to determine if combined intake of both psychostimulants can lead to maladaptive changes in striatal function. Mice were injected with a binge regimen (intermittent treatment for 13 days) of caffeine (3 × 5 mg/kg), cocaine (3 × 10 mg/kg), or combined administration...
May 2016: Neurotoxicity Research
Sergio Torres-Rueda, Stephen Rulisa, Helen E D Burchett, N Victor Mivumbi, Sandra Mounier-Jack
OBJECTIVES: Rwanda was the first country in Africa to introduce the human papillomavirus (HPV) vaccine. This was achieved through multi-year school-based campaigns. Our study evaluated the impact of the HPV vaccine introduction on the country's immunisation programme and health system. METHODS: Thirty key informants were interviewed at national and district levels, and in participating schools. Twenty-seven health facilities completed a questionnaire exploring the effects of the new vaccine introduction on six health system building blocks, as defined by the World Health Organization...
March 2016: Sexual & Reproductive Healthcare: Official Journal of the Swedish Association of Midwives
Laura J Fil, Payal Sud, Steven Sattler
Multiple sclerosis (MS) is an immune mediated inflammatory disease that attacks myelinated axons in the central nervous system. Dalfampridine (4-aminopyridine) was approved by the Food and Drug Administration in January 2010 for treatment of MS. Our patient was a 34-year-old male with a history of MS, who was brought to the emergency department after being found unresponsive. His current medications were valacyclovir, temazepam, dalfampridine (4-AP) and a tysabri intravenous (IV) infusion. Fifteen minutes after arrival the patient seized...
December 2015: Western Journal of Emergency Medicine
Malin Östman, Eva Jakobsson Ung, Kristin Falk
Living with a chronic disease like chronic heart failure (CHF) results in disruptions, losses, and setbacks in the participants' daily lives that affect health and well-being. By using grounded theory method, we illuminate whether persons with CHF experience discontinuity in life and, if so, what helps them to preserve and strengthen continuity in their daily lives. Thirteen individual interviews and one group interview with five participants, aged 62 to 88 years, were carried out. Through data collection and data analysis, we constructed three concepts that make up a model illustrating the participants' experiences in daily life in relation to corporeality, temporality, and identity: experiences of discontinuity, recapturing approaches, and reconciliation...
2015: International Journal of Qualitative Studies on Health and Well-being
Giampietro Frison, Luca Zamengo, Flavio Zancanaro, Francesco Tisato, Pietro Traldi
RATIONALE: Clinical and forensic toxicology laboratories are challenged every day by the analytical aspects of the new psychoactive substances phenomenon. In this study we describe the analytical characterization of a new ketamine derivative, deschloroketamine (2-methylamino-2-phenylcyclohexanone), contained in seized powders. METHODS: The analytical techniques employed include gas chromatography/mass spectrometry (GC/MS), liquid chromatography/electrospray ionization coupled with Orbitrap high-resolution/MS (LC/ESI-HRMS), multistage MS (ESI-MS(n)), and NMR...
January 15, 2016: Rapid Communications in Mass Spectrometry: RCM
Aree Choodum, Pichapat Boonsamran, Niamh NicDaeid, Worawit Wongniramaikul
Digital image colourimetry was successfully applied in the semi-quantitative analysis of ammonium nitrate using Griess's test with zinc reduction. A custom-built detection box was developed to enable reproducible lighting of samples, and was used with the built-in webcams of a netbook and an ultrabook for on-site detection. The webcams were used for colour imaging of chemical reaction products in the samples, while the netbook was used for on-site colour analysis. The analytical performance was compared to a commercial external webcam and a digital single-lens reflex (DSLR) camera...
December 2015: Science & Justice: Journal of the Forensic Science Society
Y Marzougui, K Missaoui, Z Hannachi, Y Dhibi, J Kouka, C Dziri, M Houissa
The postoperative peritonitis (POP) remains formidable conditions due to a high mortality rate of between 20 and 80%. The purpose of this study is to identify risk factors for mortality. This study is a retrospective, descriptive analysis carried out over a period of 09 years (1/1/2003 - 30/11/2011) and interesting 102 patients supported for POP following general surgery. Achieved in department of General Surgery B Charles Nicolle hospital Tunis. The parameters measured included epidemiological data, data related to the Initial Surgical Intervention and reoperation for POP, terms of management and evolution...
2014: Archives de L'Institut Pasteur de Tunis
Sara Ahmed, Patrick Ware, Regina Visca, Celine Bareil, Maud-Christine Chouinard, Johanne Desforges, Roderick Finlayson, Martin Fortin, Josée Gauthier, Dominique Grimard, Maryse Guay, Catherine Hudon, Lyne Lalonde, Lise Lévesque, Cecile Michaud, Sylvie Provost, Tim Sutton, Pierre Tousignant, Stella Travers, Mark Ware, Amede Gogovor
BACKGROUND: Seven chronic disease prevention and management programs were implemented across Quebec with funding support from a provincial-private industry funding initiative. Given the complexity of implementing integrated primary care chronic disease management programs, a knowledge transfer meeting was held to share experiences across programs and synthesize common challenges and success factors for implementation. METHODS: The knowledge translation meeting was held in February 2014 in Montreal, Canada...
2015: BMC Research Notes
Lyndsey M Lowe, Brianna L Peterson, Fiona J Couper
This case was submitted to the Washington State Patrol Toxicology Laboratory in September 2014. A 15-year-old male went to a party where he ingested 25I-NBOMe and mushrooms. A short time later, he started to vomit and began seizing until he eventually passed out. Resuscitation efforts were made, but were unsuccessful. He was transported to a local hospital, where he died three days later of multi-system organ failure following cardiopulmonary arrest. The hospital admission samples were negative for ethanol and basic drugs and their metabolites...
October 2015: Journal of Analytical Toxicology
Trond Myhrer, Espen Mariussen, Siri Enger, Pål Aas
A treatment regimen consisting of HI-6, levetiracetam, and procyclidine (termed the triple regimen) has previously been shown to work as a universal therapy against soman poisoning in rats, since it has capacities to function as both prophylactic and therapeutic measure. The purpose of the present study was to examine whether the triple regimen may have antidotal efficacy against intoxication by other classical nerve agents than soman. The treatment was given 1 and 5 min after exposure to a supralethal dose of nerve agents, and the results showed that the triple regimen successfully prevented or terminated seizures and preserved the lives of rats exposed to 5×LD50 of soman, sarin, cyclosarin, or VX, but solely 3×LD50 of tabun was managed by this regimen...
September 2015: Neurotoxicology
Dagmar M Haller, Anne Meynard, Danièle Lefebvre, Jennifer Hasselgård-Rowe, Barbara Broers, Françoise Narring
BACKGROUND: Family doctors can only play a role in the prevention of excessive substance use in young people if those affected are seen in the practice. OBJECTIVE: To describe the prevalence of excessive substance use among young people consulting family doctors in a European context. METHODS: As part of a trial of an intervention addressing substance use we collected data from young people consulting 32 family doctors in the French-speaking part of Switzerland...
October 2015: Family Practice
Juan L Gomez, Christopher L Cunningham, Deborah A Finn, Emily A Young, Lily K Helpenstell, Lindsey M Schuette, Tara L Fidler, Therese A Kosten, Andrey E Ryabinin
An effort has been mounted to understand the mechanisms of alcohol dependence in a way that may allow for greater efficacy in treatment. It has long been suggested that drugs of abuse seize fundamental reward pathways and disrupt homeostasis to produce compulsive drug seeking behaviors. Ghrelin, an endogenous hormone that affects hunger state and release of growth hormone, has been shown to increase alcohol intake following administration, while antagonists decrease intake. Using rodent models of dependence, the current study examined the effects of two ghrelin receptor antagonists, [DLys3]-GHRP-6 (DLys) and JMV2959, on dependence-induced alcohol self-administration...
October 2015: Neuropharmacology
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