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https://www.readbyqxmd.com/read/29288369/assessment-of-cardiovascular-risk-profile-based-on-measurement-of-tophus-volume-in-patients-with-gout
#1
Kyung-Ann Lee, Se-Ri Ryu, Seong-Jun Park, Hae-Rim Kim, Sang-Heon Lee
Hyperuricemia and gout are associated with increased risk of cardiovascular disease and metabolic syndrome. The aim of this study was to evaluate the correlation of total tophus volumes, measured using dual-energy computed tomography, with cardiovascular risk and the presence of metabolic syndrome. Dual-energy computed tomography datasets from 91 patients with a diagnosis of gout were analyzed retrospectively. Patients who received urate lowering therapy were excluded to avoid the effect on tophus volume. The total volumes of tophaceous deposition were quantified using automated volume assessment software...
December 29, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/29241303/body-fluid-status-assessment-by-bio-impedance-analysis-in-patients-presenting-to-the-emergency-department-with-dyspnea
#2
Chan Soon Park, Sang-Eun Lee, Hyun-Jai Cho, Yong-Jin Kim, Hyun-Jae Kang, Byung-Hee Oh, Hae-Young Lee
Background/Aims: Fluid retention occurs in patients with heart failure, accounting for dyspnea. We investigated the diagnostic implication of body fluid status, assessed by bio-impedance analysis (BIA), in acute heart failure (AHF) among patients who presented with dyspnea. Methods: A total of 100 patients who presented with dyspnea and suspected with AHF were analyzed in this study. We enrolled 50 AHF and 50 non-AHF patients discriminated through echocardiographic analysis and Framingham criteria and were matched by age and sex...
December 18, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29200560/a-cross-sectional-study-to-estimate-cardiovascular-risk-factors-in-patients-with-bipolar-disorder
#3
Swetha Reddy Damegunta, Prasad Rao Gundugurti
Background: There is increasing recognition of cardiovascular mortality and comorbidity in bipolar disorder (BD) in the recent times. Framingham 10 years risk of coronary heart disease (CHD) has been a widely accepted as a reliable estimate of cardiovascular risk in the general population. A few studies have estimated the relative risk of developing CHD in BDs, in India. We attempt to present a cross-sectional data from a prospective study to estimate the 10 years cardiovascular risk in BD population...
September 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/29174140/relation-of-coronary-artery-calcium-and-extra-coronary-aortic-calcium-to-incident-hypertension-from-the-multi-ethnic-study-of-atherosclerosis
#4
Amer I Aladin, Mahmoud Al Rifai, Shereen H Rasool, Zeina Dardari, Joseph Yeboah, Khurram Nasir, Matthew J Budoff, Bruce M Psaty, Roger S Blumenthal, Michael J Blaha, John W McEvoy
Arterial calcification reflects an atherosclerotic process associated with vascular stiffness. Whether baseline coronary artery calcium (CAC) and extra-coronary calcium (ECC), measured using noncontrast computed tomography imaging, are associated with incident hypertension is poorly understood. We studied participants from the Multi-Ethnic Study of Atherosclerosis without measured or self-reported hypertension at baseline. Incident hypertension was defined by blood pressure criteria (BP, ≥140/90 mmHg), BP medication use, or both, and was assessed at in-person visits...
October 24, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29165095/metabolic-syndrome-and-cardiovascular-risk-in-people-treated-with-long-acting-injectable-antipsychotics
#5
Vanessa Sanchez-Martinez, Dolores Romero-Rubio, Maria Jose Abad-Perez, Maria Amparo Descalzo-Cabades, Sofia Alonso-Gutierrez, Jose Salazar-Fraile, Vicente Montagud, Lorenzo Facila
BACKGROUND: People with schizophrenia and other severe mental disorders have an increased mortality mainly attributed to natural causes, specifically cardiovascular disease and cancer. The metabolic syndrome and the Framingham Risk Score are epidemiologic tools related to long-term cardiovascular disease risk and they are increased in people with severe mental disorders. This increase has been attributed both to the disorder itself and to the use of antipsychotic drugs. OBJECTIVE: To quantify the cardiovascular risk in a group of people treated with long-acting injectable antipsychotics...
November 20, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/29160505/metabolic-disorders-and-cardiovascular-risk-in-people-living-with-hiv-aids-without-the-use-of-antiretroviral-therapy
#6
Mariana Amaral Raposo, Geyza Nogueira de Almeida Armiliato, Nathalia Sernizon Guimarães, Camila Abrahão Caram, Raíssa Domingues de Simoni Silveira, Unaí Tupinambás
INTRODUCTION: Metabolic disorders in people living with HIV/AIDS (PLH) have been described even before the introduction of antiretroviral (ARV) drugs in the treatment of HIV infection and are risk factors for cardiovascular diseases. Based on this, the purpose of this study was to assess metabolic disorders and cardiovascular risk in PLH before the initiation of antiretroviral treatment (ART). METHODS: This was a cross-sectional descriptive study of 87 PLH without the use of ART, which was carried out between January and September 2012 at a specialized infectious diseases center in Minas Gerais, Brazil...
September 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29132438/framingham-risk-score-for-estimation-of-10-years-of-cardiovascular-diseases-risk-in-patients-with-metabolic-syndrome
#7
Leila Jahangiry, Mahdieh Abbasalizad Farhangi, Fatemeh Rezaei
BACKGROUND: There are a few studies evaluating the predictive value of Framingham risk score (FRS) for cardiovascular disease (CVD) risk assessment in patients with metabolic syndrome in Iran. Because of the emerging high prevalence of CVD among Iranian population, it is important to predict its risk among populations with potential predictive tools. Therefore, the aim of the current study is to evaluate the FRS and its determinants in patients with metabolic syndrome. METHODS: In the current cross-sectional study, 160 patients with metabolic syndrome diagnosed according to the National Cholesterol Education Adult Treatment Panel (ATP) III criteria were enrolled...
November 13, 2017: Journal of Health, Population, and Nutrition
https://www.readbyqxmd.com/read/29096792/targeted-metabolomic-profiling-of-plasma-and-survival-in-heart-failure-patients
#8
David E Lanfear, Joseph J Gibbs, Jia Li, Ruicong She, Christopher Petucci, Jeffrey A Culver, W H Wilson Tang, Yigal M Pinto, L Keoki Williams, Hani N Sabbah, Stephen J Gardell
OBJECTIVES: This study sought to derive and validate plasma metabolite associations with survival in heart failure (HF) patients. BACKGROUND: Profiling of plasma metabolites to predict the course of HF appears promising, but validation and incremental value of these profiles are less established. METHODS: Patients (n = 1,032) who met Framingham HF criteria with a history of reduced ejection fraction were randomly divided into derivation and validation cohorts (n = 516 each)...
November 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/29077762/awareness-treatment-and-control-of-dyslipidemia-in-rural-south-africa-the-haalsi-health-and-aging-in-africa-a-longitudinal-study-of-an-indepth-community-in-south-africa-study
#9
Sheridan Reiger, Thiago Veiga Jardim, Shafika Abrahams-Gessel, Nigel J Crowther, Alisha Wade, F Xavier Gomez-Olive, Joshua Salomon, Stephen Tollman, Thomas A Gaziano
Dyslipidemia is a primary driver for chronic cardiovascular conditions and there is no comprehensive literature about its management in South Africa. The objective of this study was to assess the prevalence, awareness, treatment, and control of dyslipidemia in rural South Africa and how they are impacted by different behaviors and non-modifiable factors. To fulfill this objective we recruited for this cohort study adults aged ≥40 years residing in the Agincourt sub-district of Mpumalanga Province. Data collection included socioeconomic and clinical data, anthropometric measures, blood pressure (BP), HIV-status, point-of-care glucose and lipid levels...
2017: PloS One
https://www.readbyqxmd.com/read/28990165/framingham-based-cardiovascular-risk-estimates-among-people-with-episodic-migraine-in-the-us-population-results-from-the-american-migraine-prevalence-and-prevention-ampp-study
#10
Richard B Lipton, Michael L Reed, Tobias Kurth, Kristina M Fanning, Dawn C Buse
BACKGROUND: Cardiovascular (CV) events, conditions, and procedures (ECPs) are common in persons with migraine and are a contraindication to triptan and ergot use. In a prior study, we estimated that there are 2.6 million American adults with episodic migraine (EM) who have had CV ECPs. However, the prior analysis did not assess persons with migraine without CV ECPs who are at high risk for a first cardiovascular disease (CVD) event. OBJECTIVES: To use the Framingham nonlaboratory CVD events risk equation to estimate the number of individuals with EM who are at elevated risk for a first CVD event in the next 10 years using data from the American Migraine Prevalence and Prevention Study, and then to extrapolate the findings to the US population to estimate the scope of people with EM for whom triptan and ergot therapies may be problematic...
October 9, 2017: Headache
https://www.readbyqxmd.com/read/28984639/baseline-white-matter-hyperintensities-and-hippocampal-volume-are-associated-with-conversion-from-normal-cognition-to-mild-cognitive-impairment-in-the-framingham-offspring-study
#11
Katherine J Bangen, Sarah R Preis, Lisa Delano-Wood, Philip A Wolf, David J Libon, Mark W Bondi, Rhoda Au, Charles DeCarli, Adam M Brickman
INTRODUCTION: We examined associations between magnetic resonance imaging (MRI) markers of cerebrovascular disease and neurodegeneration with mild cognitive impairment (MCI) diagnosis at baseline and conversion from normal cognition to MCI at follow-up. METHODS: Framingham Offspring participants underwent brain MRI and neuropsychological assessment at baseline (n=1049) and follow-up (n=561). Participants were classified at baseline and at follow-up as cognitively normal or MCI using sensitive neuropsychological criteria...
October 3, 2017: Alzheimer Disease and Associated Disorders
https://www.readbyqxmd.com/read/28954836/impact-of-qtc-formulae-in-the-prevalence-of-short-corrected-qt-interval-and-impact-on-probability-and-diagnosis-of-short-qt-syndrome
#12
Rui Providência, Nabeela Karim, Neil Srinivasan, Shohreh Honarbakhsh, Maria João Vidigal Ferreira, Lino Gonçalves, Eloi Marijon, Pier D Lambiase
OBJECTIVE: To assess the prevalence of short corrected QT (QTc) intervals and its impact on short QT syndrome (SQTS) diagnosis using different QT correction formulae. METHODS: Observational study. The prevalence of short QTc intervals was estimated using four different QT correction formulae in 14 662 young adults from the 'Sudden Cardiac Death Screening of Risk FactOrS' (SCD-SOS) cohort. Then, using data from this cohort and the pooled-cohort analysed by Gollob et al, comprising 61 patients with SQTS, we assessed the impact of the different QTc correction formulae on SQTS probability and diagnosis based on the Expert Consensus recommendations (QTc ≤330 ms or QTc 330-360 ms+1 additional risk feature)...
September 27, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28911021/effects-of-lifestyle-modification-on-an-exaggerated-blood-pressure-response-to-exercise-in-normotensive-females
#13
Ryoma Michishita, Masanori Ohta, Masaharu Ikeda, Ying Jiang, Hiroshi Yamato
BACKGROUND: This study was designed to examine the effects of a lifestyle modification on the improvement in an exaggerated systolic blood pressure (SBP) response to exercise in normotensive females. METHODS: The subjects were 78 normotensive females with (n = 25) and without (n = 53) an exaggerated SBP response to exercise who were not taking any medications. An exaggerated SBP response to exercise was defined according to the criteria of the Framingham Study (peak SBP: ≥190 mm Hg)...
October 1, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28893522/systolic-blood-pressure-target-in-systemic-arterial-hypertension-is-lower-ever-better-results-from-a-community-based-caucasian-cohort
#14
Concetta Di Nora, Giovanni Cioffi, Annamaria Iorio, Luigi Rivetti, Stefano Poli, Elena Zambon, Giulia Barbati, Gianfranco Sinagra, Andrea Di Lenarda
BACKGROUND: Extensive evidence exists about the prognostic role of systolic blood pressure (SBP) reduction ≤140mmHg. Recently, the SPRINT trial successfully tested the strategy of lowering SBP<120mmHg in patients with arterial hypertension (AH). AIM: To assess whether the SPRINT results are reproducible in a real world community population. METHODS: Cross-sectional, population-based study analyzing data of 24,537 Caucasian people with AH from the Trieste Observatory of CV disease, 2010 to 2015...
September 8, 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/28889188/factors-associated-with-accelerated-subclinical-atherosclerosis-in-patients-with-spondyloarthritis-without-overt-cardiovascular-disease
#15
Alessandro Giollo, Andrea Dalbeni, Giovanni Cioffi, Federica Ognibeni, Davide Gatti, Luca Idolazzi, Giovanni Orsolini, Pietro Minuz, Maurizio Rossini, Cristiano Fava, Ombretta Viapiana
Data on the progression of atherosclerosis in spondyloarthritis (SpA) are scarce, despite a high burden of cardiovascular diseases (CVD). The aim of this study was to identify the predictors of an accelerated subclinical atherosclerosis in patients with SpA. Study participants were 66 patients free of CVD classified according to ASAS criteria. The patients were evaluated at baseline and after 13.5 ± 3.6 months. Ultrasound measurements of carotid intima-media thickness (cIMT) and distensibility coefficient (cDC) were used to assess the extent of subclinical atherosclerosis...
November 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28842773/reduction-of-framingham-bmi-score-after-rapid-weight-loss-in-severely-obese-subjects-undergoing-sleeve-gastrectomy-a-single-institution-experience
#16
David Gutierrez-Blanco, David Funes-Romero, SriGita Madiraju, Federico Perez-Quirante, Emanuele Lo Menzo, Samuel Szomstein, Raul J Rosenthal
BACKGROUND: There is vast evidence that supports the importance of obesity in the pathogenesis and progression of cardiovascular disease. Rapid weight loss induced by laparoscopic Roux-en-Y gastric bypass (RYGB) and adjustable gastric banding (LAGB) has proven beneficial. The aim of this study is to evaluate laparoscopic sleeve gastrectomy (LSG) as an alternative treatment modality and its impact on the Framingham-BMI 10-year risk score. METHODS: We retrospectively reviewed all patients that underwent bariatric surgery at our institution between 2010 and 2014...
August 25, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28805026/correlation-of-6-min-walk-test-with-left-ventricular-function-and-quality-of-life-in-heart-failure-due-to-chagas-disease
#17
Mayara C Chambela, Mauro F F Mediano, Roberto R Ferreira, André M Japiassú, Mariana C Waghabi, Gilberto M S da Silva, Roberto M Saraiva
OBJECTIVES: To evaluate the correlation of the total distance walked during the six-minute walk test (6MWT) with left ventricular function and quality of life in patients with Chagas Disease (ChD) complicated by heart failure. METHODS: This is a cross-sectional study of adult patients with ChD and heart failure diagnosed based on Framingham criteria. 6MWT was performed following international guidelines. New York Heart Association functional class, brain natriuretic peptide (BNP) serum levels, echocardiographic parameters and quality of life (SF-36 and MLHFQ questionnaires) were determined and their correlation with the distance covered at the 6MWT was tested...
October 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28771097/dependency-of-cardiovascular-risk-on-reproductive-stages-and-on-age-among-middle-aged-chinese-women
#18
Y Sun, X Ruan, A O Mueck
OBJECTIVE: To assess the 10-year cardiovascular risk in middle-aged Chinese women living in the same community and the impact of reproductive aging and age. METHODS: This was a cross-sectional study in the Yuetan Community of Beijing. Data on lifestyle habits, prevalence and treatment of chronic diseases with significance for cardiovascular disease (CVD) development were collected by interview. CVD risk factors were assessed by physical examination and laboratory tests...
August 3, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28700275/guideline-based-statin-eligibility-cancer-events-and-noncardiovascular-mortality-in-the-framingham-heart-study
#19
Amit Pursnani, Joseph M Massaro, Ralph B D'Agostino, Christopher J O'Donnell, Udo Hoffmann
Purpose Cancer and cardiovascular disease share risk factors, and there is some evidence that statins reduce cancer mortality. We sought to determine the accuracy of the 2013 American College of Cardiology/American Heart Association statin eligibility criteria to identify individuals at a higher risk of developing cancer or of dying as a result of cancer or other noncardiovascular causes. Methods We included 2,196 participants (50.5 ± 8.1 years of age; 55% female) who were statin naïve and free of cancer at baseline from the offspring and third-generation cohorts of the community-based longitudinal Framingham Heart Study...
September 1, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28600367/development-and-validation-of-a-risk-stratification-model-for-prediction-of-disability-and-hospitalisation-in-patients-with-heart-failure-a-study-protocol
#20
Luis García-Olmos, Francisco Rodríguez-Salvanés, Maurice Batlle-Pérez, Río Aguilar-Torres, Carlos Porro-Fernández, Alfredo García-Cabello, Montserrat Carmona, Sergio Ruiz-Alonso, Sofía Garrido-Elustondo, Ángel Alberquilla, Luis María Sánchez-Gómez, Ricardo Sánchez de Madariaga, Elena Monge-Navarrete, Luis Benito-Ortiz, Nicolás Baños-Pérez, Amaya Simón-Puerta, Ana Belén López Rodríguez, Miguel Ángel Martínez-Álvarez, María Ángeles Velilla-Celma, María Isabel Bernal-Gómez
BACKGROUND: Chronic heart failure (CHF) reduces quality of life and causes hospitalisation and death. Identifying predictive factors of such events may help change the natural history of this condition. AIM: To develop and validate a stratification system for classifying patients with CHF, according to their degree of disability and need for hospitalisation due to any unscheduled cause, over a period of 1 year. METHODS AND ANALYSIS: Prospective, concurrent, cohort-type study in two towns in the Madrid autonomous region having a combined population of 1 32 851...
June 8, 2017: BMJ Open
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