Read by QxMD icon Read

Unilateral spastic cerebral palsy

Meta N Eek, Kate Himmelmann
Spasticity and muscle weakness is common in children with cerebral palsy (CP). Spasticity can be treated with botulinum neurotoxin-A (BoNT-A), but this drug has also been reported to induce muscle weakness. Our purpose was to describe the effect on muscle strength in the lower extremities after BoNT-A injections in children with CP. A secondary aim was to relate the effect of BoNT-A to gait pattern and range of motion. Twenty children with spastic CP were included in the study, 8 girls and 12 boys (mean age 7...
2016: Frontiers in Human Neuroscience
Aurélie Sarcher, Maxime Raison, Fabien Leboeuf, Brigitte Perrouin-Verbe, Sylvain Brochard, Raphael Gross
OBJECTIVE: Children with spastic unilateral cerebral palsy (SUCP) have an involved upper limb (IUL) restricted in active range of motion and in velocity when performing elbow extension, due to a combination of muscle impairments. One of them is excessive muscle co-activation (CA). CA usually has a functional role, particularly in joint stabilization. The aim of this study is to identify when pathological CA occurs during active elbow extension of the IUL to highlight its impact on movement restriction and to discriminate impaired muscles...
September 2016: Annals of Physical and Rehabilitation Medicine
Gursharan Kalsi, Nicola R Fry, Adam P Shortland
BACKGROUND: Our understanding of the interaction of muscle bellies and their tendons in individuals with muscle pathology is limited. Knowledge of these interactions may inform us of the effects of musculoskeletal pathologies on muscle-tendon dynamics and the subsequent neurological control strategies used in gait. Here, we investigate gastrocnemius muscle-tendon interaction in typically-developing (TD) adults and children, and in children with spastic cerebral palsy (SCP). METHODS: We recruited six TD adults (4 female; mean age: 34 yrs...
October 3, 2016: Journal of Biomechanics
Martin Staudt
No abstract text is available yet for this article.
August 13, 2016: Developmental Medicine and Child Neurology
Hsing-Ching Kuo, Claudio L Ferre, Jason B Carmel, Jaimie L Gowatsky, Arielle D Stanford, Stefan B Rowny, Sarah H Lisanby, Andrew M Gordon, Kathleen M Friel
AIM: To determine whether diffusion tensor imaging (DTI) can be an independent assessment for identifying the corticospinal tract (CST) projecting from the more-affected motor cortex in children with unilateral spastic cerebral palsy (CP). METHOD: Twenty children with unilateral spastic CP participated in this study (16 males, four females; mean age 9y 2mo [standard deviation (SD) 3y 2mo], Manual Ability Classification System [MACS] level I-III). We used DTI tractography to reconstruct the CST projecting from the more-affected motor cortex...
July 27, 2016: Developmental Medicine and Child Neurology
João Caetano Munhoz Abdo, Edilson Forlin
OBJECTIVE: To evaluate the progression of the contralateral hip after unilateral reconstruction of hip dislocation in patients classified as GMFCS IV-V; and to identify potential prognostic factors for their evolution. METHODS: This was a retrospective study on 17 patients with spastic cerebral palsy, who were classified on the GMFCS scale (Gross Motor Functional Classification System) as degrees IV and V, and who underwent unilateral reconstruction surgery to treat hip dislocation (adductor release, femoral varus osteotomy and acetabuloplasty)...
May 2016: Revista Brasileira de Ortopedia
Prakasham Rumajogee, Tatiana Bregman, Steven P Miller, Jerome Y Yager, Michael G Fehlings
Cerebral palsy (CP) is a complex multifactorial disorder, affecting approximately 2.5-3/1000 live term births, and up to 22/1000 prematurely born babies. CP results from injury to the developing brain incurred before, during, or after birth. The most common form of this condition, spastic CP, is primarily associated with injury to the cerebral cortex and subcortical white matter as well as the deep gray matter. The major etiological factors of spastic CP are hypoxia/ischemia (HI), occurring during the last third of pregnancy and around birth age...
2016: Frontiers in Neurology
Merete A Malt, Ånen Aarli, Bård Bogen, Jonas M Fevang
AIM: The Gait Deviation Index (GDI) is a score derived from three-dimensional gait analysis (3DGA). The GDI provides a numerical value that expresses overall gait pathology (ranging from 0 to 100, where 100 indicates the absence of gait pathology). The aim of this study was to investigate the association between the GDI and different levels of gross motor function [defined as the Gross Motor Function Classification System (GMFCS)] and to explore if age, height, weight, gender and cerebral palsy (CP) subclass (bilateral and unilateral CP) exert any influence on the GDI in children with unilateral and bilateral spastic CP...
June 2016: Journal of Children's Orthopaedics
Kristina Löwing, Karin Thews, Yvonne Haglund-Åkerlind, Elena M Gutierrez-Farewik
AIMS: To evaluate short and long-term effects of botulinum toxin-A combined with goal-directed physiotherapy in children with cerebral palsy (CP). METHOD: A consecutive selection of 40 children, ages 4-12 years, diagnosed with unilateral or bilateral CP, and classified in GMFCS levels I-II. During the 24 months, 9 children received one BoNT-A injection, 10 children two injections, 11 children three injections, and 10 children received four injections. 3D gait analysis, goal-attainment scaling, and body function assessments were performed before and at 3, 12, and 24 months after initial injections...
April 8, 2016: Physical & Occupational Therapy in Pediatrics
Hira Zafer, Imran Amjad, Arshad Nawaz Malik, Enfall Shaukat
OBJECTIVE: This study aims at determining the effectiveness of constraint induced movement therapy as compared to bimanual therapy for improving functional status in children with hemiplegic cerebral palsy. METHODS: This study was a randomized control trial, children (n = 20) with spastic hemiplegic cerebral palsy was randomly allocated to CIMT (constraint induced movement therapy) and BMT (bimanual therapy) group. The children with spastic hemiplegia, age between 1...
January 2016: Pakistan Journal of Medical Sciences Quarterly
Linda Nordstrand, Ann-Christin Eliasson, Marie Holmefur
AIM: The aim of the study was to describe the development of hand function, particularly the use of the affected hand in bimanual tasks, among children with unilateral cerebral palsy aged 18 months to 12 years. METHOD: A convenience sample of 96 children (53 males, 43 females) was assessed with the Assisting Hand Assessment (AHA) at regular intervals from the ages of 18 months to 12 years. The children ranged from 17 to 127 months (median age 24mo) at recruitment...
October 2016: Developmental Medicine and Child Neurology
Kathleen M Friel, Hsing-Ching Kuo, Jason Fuller, Claudio L Ferre, Marina Brandão, Jason B Carmel, Yannick Bleyenheuft, Jaimie L Gowatsky, Arielle D Stanford, Stefan B Rowny, Bruce Luber, Bruce Bassi, David L K Murphy, Sarah H Lisanby, Andrew M Gordon
Background Intensive bimanual therapy can improve hand function in children with unilateral spastic cerebral palsy (USCP). We compared the effects of structured bimanual skill training versus unstructured bimanual practice on motor outcomes and motor map plasticity in children with USCP. Objective We hypothesized that structured skill training would produce greater motor map plasticity than unstructured practice. Methods Twenty children with USCP (average age 9.5; 12 males) received therapy in a day camp setting, 6 h/day, 5 days/week, for 3 weeks...
October 2016: Neurorehabilitation and Neural Repair
Damien Vitiello, Ludmilla Pochon, Davide Malatesta, Olivier Girard, Christopher J Newman, Francis Degache
BACKGROUND: Fatigue is likely to be an important limiting factor in adolescents with spastic cerebral palsy (CP). AIMS: To determine the effects of walking-induced fatigue on postural control adjustments in adolescents with unilateral CP and their typically developing (TD) peers. METHODS: Ten adolescents with CP (14.2 ± 1.7 yr) and 10 age-, weight- and height-matched TD adolescents (14.1 ± 1.9 yr) walked for 15 min on a treadmill at their preferred walking speed...
June 2016: Research in Developmental Disabilities
Pieter Meyns, Leen Van Gestel, Inge Leunissen, Paul De Cock, Stefan Sunaert, Hilde Feys, Jacques Duysens, Kaat Desloovere, Els Ortibus
Background Even though lower-limb motor disorders are core features of spastic cerebral palsy (sCP), the relationship with brain lesions remains unclear. Unraveling the relation between gait pathology, lower-limb function, and brain lesions in sCP is complex for several reasons; wide heterogeneity in brain lesions, ongoing brain maturation, and gait depends on a number of primary motor functions/deficits (eg, muscle strength, spasticity). Objective To use a comprehensive approach combining conventional MRI and diffusion tensor imaging (DTI) in children with sCP above 3 years old to relate quantitative parameters of brain lesions in multiple brain areas to gait performance...
October 2016: Neurorehabilitation and Neural Repair
Hsing-Ching Kuo, Andrew M Gordon, Aline Henrionnet, Sylvie Hautfenne, Kathleen M Friel, Yannick Bleyenheuft
Children with unilateral spastic cerebral palsy (USCP) often have tactile impairments. Intensive bimanual training improves the motor abilities, but the effects on the sensory system have not been studied. Here we compare the effects of bimanual training with and without tactile training on tactile impairments. Twenty children with USCP (6-15.5 years; MACS: I-III) were randomized to receive either bimanual therapy (HABIT) or HABIT+tactile training (HABIT+T). All participants received 82 h of standardized HABIT...
February 2016: Research in Developmental Disabilities
Hsieh-ching Chen, Lin-ju Kang, Chia-ling Chen, Keh-chung Lin, Fei-chuan Chen, Katie P H Wu
AIMS: To examine the differences in efficacy of home-based constraint-induced therapy (CIT) on functional outcomes and motor control in two age groups of children with cerebral palsy (CP). METHODS: Twenty-three children with spastic unilateral CP receiving 4-week home-based CIT by a therapist were divided into younger (6-8 years; n = 11) and older (9-12 years; n = 12) groups. The home-based CIT involved intensive functional training of the more affected upper-limb while restraining the less affected upper-limb...
2016: Physical & Occupational Therapy in Pediatrics
Dayna Pool, Catherine Elliott, Natasha Bear, Cyril J Donnelly, Caroline Davis, Katherine Stannage, Jane Valentine
AIM: To determine if neuromuscular electrical stimulation (NMES) applied to the ankle dorsiflexors during gait improves muscle volume and strength in children with unilateral spastic cerebral palsy (CP). METHOD: Thirty-two children (15 females, 17 males; mean age 10y 8mo, age range 5y 5mo-18y 1mo) with unilateral spastic CP and a Gross Motor Function Classification System of level I or level II were randomly assigned to either the 8-week daily NMES treatment group or control group (usual or conventional treatments)...
May 2016: Developmental Medicine and Child Neurology
Dayna Pool, Jane Valentine, Natasha Bear, Cyril J Donnelly, Catherine Elliott, Katherine Stannage
BACKGROUND: The purpose of this study was to determine the orthotic and therapeutic effects of daily community applied FES to the ankle dorsiflexors in a randomized controlled trial. We hypothesized that children receiving the eight-week FES treatment would demonstrate orthotic and therapeutic effects in gait and spasticity as well as better community mobility and balance skills compared to controls not receiving FES. METHODS: This randomized controlled trial involved 32 children (mean age 10 yrs 3 mo, SD 3 yrs 3 mo; 15 females, 17 males) with unilateral spastic cerebral palsy and a Gross Motor Function Classification System of I or II randomly assigned to a FES treatment group (n = 16) or control group (n = 16)...
2015: BMC Pediatrics
Berno Misgeld, Markus Luken, Daniel Heitzmann, Sebastian Wolf, Steffen Leonhardt
Spasticity is a common disorder of the skeletal muscle with a high incidence in industrialised countries. A quantitative measure of spasticity using body-worn sensors is important in order to assess rehabilitative motor training and to adjust the rehabilitative therapy accordingly. We present a new approach to spasticity detection using the Integrated Posture and Activity NEtwork by Medit Aachen (IPANEMA) body sensor network (BSN). For this, a new electromyography (EMG) sensor node was developed and employed in human locomotion...
September 8, 2015: IEEE Journal of Biomedical and Health Informatics
A L Kurenkov, O A Klochkova, Kh M Karimova, B I Bursagova, L S Namazova-Baranova, L M Kuzenkova, A M Mamedyarov, A R Artemenko, S A Petrova
AIM: To analyze the efficacy and safety of dose ranges of abobotulinum toxin A (BTA) for multilevel injections into upper and lower extremity muscles in children with spastic forms of cerebral palsy (CP). MATERIAL AND METHODS: We analyzed retrospectively multilevel BTA injections for 216 patients, aged from 2 to 17 years. Children received 1-6 repeated injections and complex physiotherapy. Patients were classified according to the GMFCS. Treatment results were evaluated with the modified Ashworth and Tardieu scales...
2015: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"