keyword
MENU ▼
Read by QxMD icon Read
search

Functional gastrointestinal disorders

keyword
https://www.readbyqxmd.com/read/29147653/health-status-and-the-demand-for-healthcare-among-the-elderly-in-the-rural-quoc-oai-district-of-hanoi-in-vietnam
#1
Kyung-Sook Bang, Sunghee H Tak, Juhwan Oh, Jinseon Yi, Soo-Young Yu, Truong Quang Trung
Background: Vietnam is experiencing an unprecedented demographic transition. Its proportion of elderly people is growing rapidly. Objective: This study explored the health status and health-related quality of life (HRQoL) of rural elderly Vietnamese and assessed their needs for healthcare services. Design: This study used a survey with stratified proportion sampling and quota assignment. In 2016, data was collected from 713 people in the rural Quoc-Oai district of Hanoi aged 60 or older...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29139561/the-novel-potent-and-highly-selective-5-ht4-receptor-agonist-yh12852-significantly-improves-both-upper-and-lower-gastrointestinal-motility
#2
Eun Jeong Jeong, Soo Yong Chung, Han Na Hong, Se-Woong Oh, Jae Young Sim
BACKGROUND AND PURPOSE: 5-HT4 receptor agonists have been shown to be effective to treat various gastrointestinal tract disorders. However, a lack of selectivity against off-targets has been a limiting factor. EXPERIMENTAL APPROACH: The binding affinity and selectivity of YH12852 for human 5-HT4(a) receptor in CHO-K1 cells were evaluated using radioligand binding assays, and agonistic activity was assessed using a beta-lactamase reporter system. Contractile activity and propulsive motility were measured in isolated guinea pig distal colon...
November 15, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/29138194/the-costs-of-functional-gastrointestinal-disorders-and-related-signs-and-symptoms-in-infants-a-systematic-literature-review-and-cost-calculation-for-england
#3
James Mahon, Carlos Lifschitz, Thomas Ludwig, Nikhil Thapar, Julie Glanville, Mohamad Miqdady, Miguel Saps, Seng Hock Quak, Irene Lenoir Wijnkoop, Mary Edwards, Hannah Wood, Hania Szajewska
OBJECTIVES: To estimate the cost of functional gastrointestinal disorders (FGIDs) and related signs and symptoms in infants to the third party payer and to parents. STUDY DESIGN: To estimate the cost of illness (COI) of infant FGIDs, a two-stage process was applied: a systematic literature review and a COI calculation. As no pertinent papers were found in the systematic literature review, a 'de novo' analysis was performed. For the latter, the potential costs for the third party payer (the National Health Service (NHS) in England) and for parents/carers for the treatment of FGIDs in infants were calculated, by using publicly available data...
November 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/29138116/in-silico-identification-of-genes-involved-in-chronic-metabolic-acidosis
#4
Ishfaq A Sheikh, Adeel Malik, Sameera F M AlBasri, Mohd A Beg
AIMS: Chronic metabolic acidosis (CMA) refers to increased plasma acidity due to disturbed acid-base equilibrium in human body. CMA leads to many dysfunctions including disorders of intestinal metabolism and barrier functions. The human body responds to these intestinal dysfunctions by creating a compensatory mechanism at genomic level in intestinal epithelial cells. This study was to identify the molecular pathways involved in metabolic dysfunction and compensatory adaptations in intestinal epithelium during CMA...
November 11, 2017: Life Sciences
https://www.readbyqxmd.com/read/29135035/analysis-and-measurement-of-serotonin
#5
REVIEW
András Seitz, Stelvio M Bandiera
Serotonin, also known as 5-hydroxytryptamine, is an important signaling molecule in the central and peripheral nervous systems of humans. Acting through several receptor types, it helps regulate the normal functioning of the gastrointestinal tract, cardiovascular system and brain. Serotonin signaling has also been implicated in the etiology of several diseases, including depression, anxiety disorders, hypertension and irritable bowel syndrome. The present review focuses on the chemical analysis of serotonin in biological fluids and biomatrices and traces the development and application of early methods based on UV absorbance or fluorescence to more widely-used current methods such as high-performance liquid chromatography coupled to mass spectrometry...
November 14, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/29134969/the-prevalence-and-impact-of-overlapping-rome-iv-diagnosed-functional-gastrointestinal-disorders-on-somatization-quality-of-life-and-healthcare-utilization-a-cross-sectional-general-population-study-in-three-countries
#6
Imran Aziz, Olafur S Palsson, Hans Törnblom, Ami D Sperber, William E Whitehead, Magnus Simrén
OBJECTIVES: The population prevalence of Rome IV-diagnosed functional gastrointestinal disorders (FGIDs) and their cumulative effect on health impairment is unknown. METHODS: An internet-based cross-sectional health survey was completed by 5,931 of 6,300 general population adults from three English-speaking countries (2100 each from USA, Canada, and UK). Quota-based sampling was used to generate demographically balanced and population representative samples with regards to age, sex, and education level...
November 14, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29134293/medicinal-foods-for-functional-gi-disorders
#7
REVIEW
Brent W Acker, Brooks D Cash
PURPOSE OF REVIEW: Over the past 10 years, there has been a dramatic increase in basic and clinical research involving functional gastrointestinal disorders (FGIDs). New diagnostic and biomarker procedures are helping to identify physiologic disruptions associated with FGIDs on cellular and molecular levels. Simultaneously, clinicians are using new approaches to help manage patients with FGIDs. Among these, an important component of care has been the use of medical foods. These include probiotics, prebiotics, synbiotics, peppermint oil, caraway oil, curcumin, bovine immunoglobulin and many others...
November 13, 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/29130724/probiotics-for-fibromyalgia-study-design-for-a-pilot-double-blind-randomized-controlled-trial
#8
Pablo Roman, Ángeles F Estévez, Nuria Sánchez-Labraca, Fernando Cañadas, Alonso Miras, Diana Cardona
BACKGROUND: Fibromyalgia syndrome (FMS) is a chronic, generalized and diffuse pain disorder accompanied by other symptoms such as emotional and cognitive deficits. The FMS patients show a high prevalence of gastrointestinal symptoms. Recently it has been found that microbes in the gut may regulate brain processes through the gut-microbiota-brain axis, modulating thus affection, motivation and higher cognitive functions. Therefore, the use of probiotics might be a new treatment that could improve the physical, psychological and cognitive state in FMS; however, no evidence about this issue is available...
October 24, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29130220/-current-research-progress-and-thinking-of-fecal-microbiota-transplantation-for-the-treatment-of-gastrointestinal-disorders
#9
Ning Li, Hongliang Tian
Fecal microbiota transplantation (FMT), also known as fecal bacteriotherapy or fecal infusion, consists of injection of a liquid filtrate of feces from a healthy donor into the gastrointestinal tract of a recipient individual. FMT has been proposed as a therapeutic approach for functional diseases of the gastrointestinal tract by reestablishment of a wide diversity of intestinal flora. Clostridium difficile infection (CDI) treatment guideline from American Gastroenterology Association (AGA) recommends that FMT can be used as the treatment protocols of relapse CDI...
October 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29129667/prevalence-of-functional-gastrointestinal-disorders-in-children-and-adolescents-in-the-mediterranean-region-of-europe
#10
Elena Scarpato, Sanja Kolacek, Danijela Jojkic-Pavkov, Vlatka Konjik, Nataša Živković, Enriqueta Roman, Aco Kostovski, Nikolina Zdraveska, Eyad Altamimi, Alexandra Papadopoulou, Thomai Karagiozoglou-Lampoudi, Raanan Shamir, Michal Rozenfeld Bar Lev, Aziz Koleilat, Sirin Mneimneh, Dario Bruzzese, Rosaura Leis, Annamaria Staiano, Panayota Kafritsa, Sandra Brusa, Angelo Campanozzi, Claudio Romano, Silvia Salvatore, Evelina Kotzakioulafi, Josefa Barrio, Maria Luz Cilleruelo, Mercedes Juste, Carolina Gutiérrez-Junquera, Tena Trbojević, Lana Ivković
BACKGROUND & AIMS: Little is known about the prevalence of functional gastrointestinal disorders (FGIDs) in children from the Mediterranean area of Europe. We aimed to assess the prevalence of FGIDs in children and adolescents in this region. METHODS: We collected data on 13,750 children (4-18 years old) enrolled in the Mediterranean-European Area Project, a school-based health study performed in Croatia, Greece, Israel, Italy, Jordan, Lebanon, Macedonia, Serbia, and Spain...
November 9, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29128338/association-between-defective-spleen-function-and-primary-eosinophilic-gastrointestinal-disorders
#11
Antonio Di Sabatino, Nicola Aronico, Paolo Giuffrida, Sara Cococcia, Marco Vincenzo Lenti, Alessandro Vanoli, Marco Guerci, Michele Di Stefano, Gino Roberto Corazza
No abstract text is available yet for this article.
November 8, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29122501/psychoneuroimmunological-approach-to-gastrointestinal-related-pain
#12
REVIEW
Karlo Toljan, Bruce Vrooman
BACKGROUND AND PURPOSE (AIMS): Psychoneuroimmunology is both a theoretical and practical field of medicine in which human biology and psychology are considered an interconnected unity. Through such a framework it is possible to elucidate complex syndromes in gastrointestinal related pain, particularly chronic non-malignant. The aim is to provide insight into pathophysiological mechanisms and suggest treatment modalities according to a comprehensive paradigm. The article also presents novel findings that may guide clinicians to recognize new targets or scientists to find new research topics...
November 6, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29113464/a-new-treatment-strategy-for-parkinson-s-disease-through-the-gut-brain-axis-the-glucagon-like-peptide-1-receptor-pathway
#13
Dong Seok Kim, Ho-Il Choi, Yun Wang, Yu Luo, Barry J Hoffer, Nigel H Greig
Molecular communications in the gut-brain axis, between the central nervous system and the gastrointestinal tract, are critical for maintaining healthy brain function, particularly in aging. Epidemiological analyses indicate type 2 diabetes mellitus (T2DM) is a risk factor for neurodegenerative disorders including Alzheimer's disease (AD) and Parkinson's diseases (PD) for which aging shows a major correlative association. Common pathophysiological features exist between T2DM, AD, and PD, including oxidative stress, inflammation, insulin resistance, abnormal protein processing, and cognitive decline, and suggest that effective drugs for T2DM that positively impact the gut-brain axis could provide an effective treatment option for neurodegenerative diseases...
September 2017: Cell Transplantation
https://www.readbyqxmd.com/read/29112549/european-guidelines-on-perioperative-venous-thromboembolism-prophylaxis-patients-with-preexisting-coagulation-disorders-and-after-severe-perioperative-bleeding
#14
Aamer Ahmed, Sibylle Kozek-Langenecker, François Mullier, Sue Pavord, Cedric Hermans
: In patients with inherited bleeding disorders undergoing surgery, we recommend assessment of individual risk for venous thromboembolism, taking into account the nature of the surgery and anaesthetic, type and severity of bleeding disorder, age, BMI, history of thrombosis, the presence of malignancy and other high-risk comorbidities. Venous thromboembolism risk should be balanced against the increased bleeding risk associated with anticoagulant use in patients with known bleeding disorders (Grade 1C). In these patients undergoing major surgery, we recommend against routine postoperative use of pharmacological thromboprophylaxis, especially for patients with haemophilia A and B (Grade 1B)...
November 6, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/29112086/randomized-controlled-clinical-trial-on-value-of-domperidone-in-functional-abdominal-pain-in-children
#15
Amaranath Karunanayake, Niranga M Devanarayana, Asita de Silva, Sampath Gunawardena, Shaman Rajindrajith
OBJECTIVES: The aim of the study was to evaluate the therapeutic effect of domperidone on children with abdominal pain predominant functional gastrointestinal disorders (AP-FGIDs). METHODS: One hundred children (aged 5-12 years) fulfilling Rome III criteria for AP-FGIDs were randomized into 8 weeks of domperidone or placebo treatment. Primary outcomes defined were cure and patient-reported general improvement. Secondary outcomes were reduction in the severity of abdominal pain and increase in gastric motility...
November 3, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29111202/intestinal-fructose-malabsorption-is-associated-with-increased-lactulose-fermentation-in-the-intestinal-lumen-of-patients-with-abdominal-pain
#16
Roberto Koity Fujihara Ozaki, Patrícia da Graça Leite Speridião, Ana Cristina Fontenele Soares, Mauro Batista de Morais
OBJECTIVE: To study fructose malabsorption in children and adolescents with abdominal pain associated with functional gastrointestinal disorders. As an additional objective, the association between intestinal fructose malabsorption and food intake, including the estimated fructose consumption, weight, height, and lactulose fermentability were also studied. METHODS: The study included 31 patients with abdominal pain (11 with functional dyspepsia, 10 with irritable bowel syndrome, and 10 with functional abdominal pain)...
October 28, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/29108960/perioperative-morbidity-bowel-function-and-oncologic-outcome-after-radical-cystectomy-and-ileal-orthotopic-neobladder-reconstruction-studer-pouch-versus-i-pouch
#17
Johannes Mischinger, Mohamed F Abdelhafez, Steffen Rausch, Tilman Todenhöfer, Eva Neumann, Stefan Aufderklamm, Arnulf Stenzl, Georgios Gakis
OBJECTIVE: To investigate whether the length of ileum used for ileal orthotopic neobladder (ONB) reconstruction (60 cm vs. 40 cm) after radical cystectomy (RC) for bladder cancer (BC) impacts on bowel function, postoperative complications or survival outcome. MATERIAL AND METHODS: In this retrospective study, we included 56 patients who received an ONB (Studer (S)-Pouch: 23 patients; I-Pouch: 33 patients) after RC for BC between 2003 and 2011. Preoperative comorbidities were assessed by the Charlson Comorbidity Index (CCI) and surgical complications as graded by the Clavien-Dindo classification...
October 20, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29105152/proton-pump-inhibitor-alters-oral-microbiome-in-gastrointestinal-tract-of-healthy-volunteers
#18
Tsuyoshi Mishiro, Kentaro Oka, Yasutoshi Kuroki, Motomichi Takahashi, Kasumi Tatsumi, Tsukasa Saitoh, Hiroshi Tobita, Norihisa Ishimura, Shuichi Sato, Shunji Ishihara, Joji Sekine, Koichiro Wada, Yoshikazu Kinoshita
BACKGROUND AND AIM: Acid suppressive agents including proton pump inhibitors (PPIs) are used as first-line treatment for various acid-related gastrointestinal disorders. Although known to profoundly reduce gastric acid production, their influence on inhibition of acid secretion as part of the function of the gastrointestinal tract microbiome remains to be elucidated. The aim of the present study was to examine the effects of PPI usage on oral and gut microbiota in healthy volunteers. METHODS: Ten healthy adult volunteers receiving no medications were enrolled...
November 4, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29103329/identification-and-validation-of-functional-gastrointestinal-disorder-subtypes-using-latent-class-analysis-a-population-based-study
#19
Alan R Zinsmeister, Linda M Herrick, Yuri A Saito Loftus, Cathy D Schleck, Nicholas J Talley
OBJECTIVE: Attempts to categorize distinct functional gastrointestinal disorders based on reported symptoms continue but symptoms frequently overlap. The study objective was to use latent class analysis (LCA) which accommodates both continuous and discrete manifest variables to determine mutually exclusive subgroup assignments of a population-based sample using gastrointestinal symptom and patient data. MATERIALS AND METHODS: A validated bowel disease questionnaire and somatic symptom questionnaire were mailed to an age and gender stratified randomly selected community sample...
November 6, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29099770/adenosine-a2b-receptors-an-optional-target-for-the-management-of-irritable-bowel-syndrome-with-diarrhea
#20
REVIEW
Teita Asano, Mitsuko Takenaga
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder, with the characteristic symptoms of chronic abdominal pain and altered bowel habits (diarrhea, constipation, or both). IBS is a highly prevalent condition, which negatively affects quality of life and is a significant burden on global healthcare costs. Although many pharmacological medicines have been proposed to treat IBS, including those targeting receptors, channels, and chemical mediators related to visceral hypersensitivity, successful pharmacotherapy for the disease has not been established...
November 3, 2017: Journal of Clinical Medicine
keyword
keyword
92894
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"