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https://www.readbyqxmd.com/read/29327166/loneliness-in-psychosis-a-systematic-review
#1
REVIEW
Michelle H Lim, John F M Gleeson, Mario Alvarez-Jimenez, David L Penn
PURPOSE: The aim of the review is to understand the relationships between loneliness and related psychological and social factors in individuals with psychosis. Loneliness is poorly understood in people with psychosis. Given the myriad of social challenges facing individuals with psychosis, these findings can inform psychosocial interventions that specifically target loneliness in this vulnerable group. METHODS: We adhered to the PRISMA guidelines and systematically reviewed empirical studies that measured loneliness either as a main outcome or as an associated variable in individuals with psychosis...
January 11, 2018: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/29282075/psychometric-validation-of-a-multi-dimensional-capability-instrument-for-outcome-measurement-in-mental-health-research-oxcap-mh
#2
Francis Vergunst, Crispin Jenkinson, Tom Burns, Paul Anand, Alastair Gray, Jorun Rugkåsa, Judit Simon
BACKGROUND: Patient reported outcome measures (PROMs) are widely used in mental healthcare research for quality of life assessment but most fail to capture the breadth of health and non-health domains that can be impacted. We report the psychometric validation of a novel, multi-dimensional instrument based on Amartya Sen's capability approach intended for use as an outcome measure in mental health research. METHODS: The Oxford Capabilities Questionnaire for Mental Health (OxCAP-MH) is a 16-item self-complete capability measure that covers multiple domains of functioning and welfare...
December 28, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29273021/randomised-controlled-trial-to-improve-health-and-reduce-substance-use-in-established-psychosis-impact-cost-effectiveness-of-integrated-psychosocial-health-promotion
#3
Margaret Heslin, Anita Patel, Daniel Stahl, Poonam Gardner-Sood, Manyara Mushore, Shubulade Smith, Kathryn Greenwood, Oluwadamilola Onagbesan, Conan O'Brien, Catherine Fung, Ruth Ohlsen, David Hopkins, Philippa Lowe, Maurice Arbuthnot, Stan Mutatsa, Gill Todd, Anna Kolliakou, John Lally, Brendon Stubbs, Khalida Ismail, Anthony David, Robin Murray, Zerrin Atakan, Fiona Gaughran
BACKGROUND: There is mounting evidence that people with severe mental illness have unhealthy lifestyles, high rates of cardiovascular and metabolic diseases, and greater risk of early mortality. This study aimed to assess the cost-effectiveness of a health promotion intervention seeking to improve physical health and reduce substance use in people with psychosis. METHODS: Participants with a psychotic disorder, aged 18-65 years old and registered on an enhanced care approach programme or equivalent were recruited from community mental health teams in six mental health trusts in England...
December 22, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29261427/addiction-vulnerability-exploring-relationships-between-cigarette-smoking-substance-misuse-and-early-psychosis
#4
Vanessa Clark, Agatha M Conrad, Terry J Lewin, Amanda L Baker, Sean A Halpin, Ketrina A Sly, Juanita Todd
OBJECTIVE: Smoking rates in adolescents at risk of psychosis are significantly greater than those who are not at risk. Recent research suggests that cigarette smoking in adolescence may be a potential marker of transition to psychosis, although the exact relationship between the two remains unclear. Our aim was to examine whether tobacco smoking is a potential marker of transition to psychosis or subsequent episodes of psychosis, independently of other substance use, or alternatively, if smoking is essentially a general marker of later mental illness episodes...
December 20, 2017: Journal of Dual Diagnosis
https://www.readbyqxmd.com/read/29215319/examining-the-potential-preventative-effects-of-minocycline-prescribed-for-acne-on-the-incidence-of-severe-mental-illnesses-a-historical-cohort-study
#5
Maria Herrero-Zazo, Ruth Brauer, Fiona Gaughran, Louise M Howard, David Taylor, David J Barlow
BACKGROUND: Animal studies suggest that the antibiotic and microglial activation inhibitor, minocycline, is likely to have a protective effect against the emergence of psychosis but evidence from human studies is lacking. The aim of this study is to examine the effects of exposure to minocycline during adolescence on the later incidence of severe mental illness (SMI). METHODS: A historical cohort study using electronic primary care data was conducted to assess the association between exposure to minocycline during adolescence and incidence of SMI...
December 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/29202427/religiosity-and-religious-delusions-in-schizophrenia-an-observational-study-in-a-hindu-population
#6
Anand Mishra, Basudeb Das, Nishant Goyal
BACKGROUND: Religion exerts a significant effect on the lives of many individuals including people with mental illness. As evidences keep accumulating, role of religion in mental illness is gaining importance. OBJECTIVES: The study was designed to study the effects of religiosity on religious delusions, its presentation, acute course and outcome in schizophrenia. METHOD: The study was a naturalistic observational study. Subjects with schizophrenia were grouped into those with religious (RG) and with non-religious delusions (NG)...
November 27, 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29186169/epidemiology-of-severe-mental-illness-in-hunan-province-in-central-china-during-2014-2015-a-multistage-cross-sectional-study
#7
Dongxin Wang, Jing Ma, Lihong Tan, Yan Chen, Xiaosong Li, Xuefei Tian, Xuhui Zhou, Xuejun Liu
OBJECTIVE: Severe mental illness (SMI) represents major social and public health problem in China, especially in low- or middle-income regions. We aim to assess the prevalence and distribution of SMI in Hunan province in central China. METHODS: Multistage stratified random sampling methods were used to select qualified subjects in 123 districts and counties in Hunan province. 89465 individuals were randomly identified, and 72999 (81.6%) completed the supplemental 12-Item General Health Questionnaire (GHQ-12) and Cue questionnaire of psychiatric abnormal behaviors...
2017: PloS One
https://www.readbyqxmd.com/read/29179576/rates-and-predictors-of-conversion-to-schizophrenia-or-bipolar-disorder-following-substance-induced-psychosis
#8
Marie Stefanie Kejser Starzer, Merete Nordentoft, Carsten Hjorthøj
OBJECTIVE: The authors investigated the rates of conversion to schizophrenia and bipolar disorder after a substance-induced psychosis, as well as risk factors for conversion. METHOD: All patient information was extracted from the Danish Civil Registration System and the Psychiatric Central Research Register. The study population included all persons who received a diagnosis of substance-induced psychosis between 1994 and 2014 (N=6,788); patients were followed until first occurrence of schizophrenia or bipolar disorder or until death, emigration, or August 2014...
November 28, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/29178895/informed-advance-refusals-of-treatment-by-people-with-severe-mental-illness-in-a-randomised-controlled-trial-of-joint-crisis-plans-demand-content-and-correlates
#9
Claire Henderson, Simone Farrelly, Clare Flach, Rohan Borschmann, Max Birchwood, Graham Thornicroft, Waquas Waheed, George Szmukler
BACKGROUND: In the UK, crisis planning for mental health care should acknowledge the right to make an informed advance treatment refusal under the Mental Capacity Act 2005. Our aims were to estimate the demand for such treatment refusals within a sample of service users who had had a recent hospital admission for psychosis or bipolar disorder, and to examine the relationship between refusals, and service user characteristics. METHODS: To identify refusals we conducted content analysis of Joint Crisis Plans, which are plans formulated by service users and their clinical team with involvement from an external facilitator, and routine care plans in sub-samples from a multi-centre randomised controlled trial of Joint Crisis Plans (plus routine mental health care) versus routine care alone (CRIMSON) in England...
November 24, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29172178/a-10-year-follow-up-study-of-violent-victimization-in-first-episode-psychosis-risk-and-protective-factors
#10
Johannes Langeveld, Stål Bjørkly, Julie Evensen, Inge Joa, Jan Olav Johannessen, Tor Ketil Larsen, Ingrid Melle, Stein Opjordsmoen, Jan Ivar Røssberg, Bjørn Rishovd Rund, Erik Simonsen, Per Vaglum, Wenche Ten Velden, Tom McGlashan, Svein Friis
Violent victimization in persons with severe mental illness has long-term adverse consequences. Little is known about the long-term prevalence of victimization in first episode psychosis, or about factors affecting victimization throughout the course of illness. To assess the prevalence of violent victimization during a 10-year follow-up period in a group of first episode psychosis (FEP) patients, and to identify early predictors and risk factors for victimization. A prospective design was used with comprehensive assessments of violent victimization, treatment variables and functioning at baseline and during 10-year follow-up...
November 7, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29141785/environmental-adversities-and-psychotic-symptoms-the-impact-of-timing-of-trauma-abuse-and-neglect
#11
Inga Schalinski, Susanne Breinlinger, Vanessa Hirt, Martin H Teicher, Michael Odenwald, Brigitte Rockstroh
BACKGROUND: Trauma and adverse childhood experiences (ACE) occur more often in mental illness, including psychosis, than in the general population. Individuals with psychosis (cases) report a higher number and severity (dose) of adversities than healthy controls. While a dose-dependent increase of adversities has been related to more severe psychopathology, the role of type and timing is still insufficiently understood on the exacerbation of positive and negative psychotic symptoms. Moreover, dissociative symptoms were examined as potential mediator between adversities and severity of psychotic symptoms...
November 13, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/29134852/psychosis-and-sexual-offending-a-review-of-current-literature
#12
E Thomas Lewis, R Gregg Dwyer
Sexual offending is a public health concern and societal risk requiring a multi-disciplinary approach. While current data give an indication of the frequency of sexual victimization, these figures likely underestimate the severity of the concern as many of these incidents go unreported. And while sex offender research has increased over the past several decades, particular attention to those offenders with severe mental illness remains limited. In this descriptive review, literature describing sex offenders with psychotic disorders is explored with a focus on recent research...
November 1, 2017: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/29122420/locked-in-and-growing-old-the-psychiatric-forensic-and-cognitive-correlates-of-30-years-of-psychiatric-hospitalization
#13
Frederick Hives, Kenny A Karyadi, Steve Nitch, Dominique Kinney
OBJECTIVE: As the number of older adults in the United States continues to grow, the population of older adults with severe mental illness in institutional settings (OASIS) is expected to place a significant demand on healthcare resources. This study presents an update to research regarding the clinical characteristics of OASIS inpatients with histories of extensive hospitalization through the use of a newly developed psychiatric measure: the Clinician-Rated Dimension of Psychosis Symptom Severity...
October 12, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29076240/negative-symptoms-of-psychosis-a-life-course-approach-and-implications-for-prevention-and-treatment
#14
REVIEW
John Lyne, Brian O'Donoghue, Eric Roche, Laoise Renwick, Mary Cannon, Mary Clarke
AIM: Negative symptoms are a cause of enduring disability in serious mental illness. In spite of this, the development of effective treatments for negative symptoms has remained slow. The challenge of improving negative symptom outcomes is compounded by our limited understanding of their aetiology and longitudinal development. METHODS: A literature search was conducted for life course approach of negative symptoms using PubMed. Further articles were included following manual checking of reference lists and other search strategies...
October 27, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29071372/olfactory-deficits-in-individuals-at-risk-for-psychosis-and-patients-with-schizophrenia-relationship-with-socio-cognitive-functions-and-symptom-severity
#15
Tsutomu Takahashi, Mihoko Nakamura, Daiki Sasabayashi, Yuko Komori, Yuko Higuchi, Yumiko Nishikawa, Shimako Nishiyama, Hiroko Itoh, Yuri Masaoka, Michio Suzuki
Odor identification deficits are well documented in patients with schizophrenia, but it remains unclear whether individuals at clinical high-risk for psychosis exhibit similar changes and whether their olfactory function is related to social/cognitive functions and symptomatology. In this study, we investigated odor detection sensitivity and identification ability in 32 individuals with at-risk mental state (ARMS), 59 schizophrenia patients, and 169 healthy controls using a T&T olfactometer. The ARMS and schizophrenia subjects were administered the Brief Assessment of Cognition in Schizophrenia (BACS), the Schizophrenia Cognition Rating Scale (SCoRS), and the Social and Occupational Functioning Assessment Scale (SOFAS) to assess their cognitive and social functions, and the Positive and Negative Syndrome Scale (PANSS) for clinical symptoms...
October 25, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/29070081/understanding-the-experience-of-initiating-community-based-physical-activity-and-social-support-by-people-with-serious-mental-illness-a-systematic-review-using-a-meta-ethnographic-approach
#16
Helen Quirk, Helen Crank, Deborah Harrop, Emma Hock, Robert Copeland
BACKGROUND: People with long-term serious mental illness live with severe and debilitating symptoms that can negatively influence their health and quality of life, leading to outcomes such as premature mortality, morbidity and obesity. An interplay of social, behavioural, biological and psychological factors is likely to contribute to their poor physical health. Participating in regular physical activity could bring symptomatic improvements, weight loss benefits, enhanced wellbeing and when undertaken in a community-based group setting can yield additional, important social support benefits...
October 25, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/29065870/crucial-factors-preceding-compulsory-psychiatric-admission-a-qualitative-patient-record-study
#17
Mark H de Jong, Margreet Oorschot, Astrid M Kamperman, Petra E Brussaard, Esther M Knijff, Roland van de Sande, Arthur R Van Gool, Cornelis L Mulder
BACKGROUND: Compulsory admissions have a strong effect on psychiatric patients and represent a deprivation of personal liberty. Although the rate of such admissions is tending to rise in several Western countries, there is little qualitative research on the mental health-care process preceding compulsory admission. The objective of the study was to identify crucial factors in the mental health-care process preceding compulsory admission of adult psychiatric patients. METHODS: This retrospective, qualitative multiple-case study was based on the patient records of patients with severe mental illness, mainly schizophrenia and other psychotic disorders...
October 24, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29032700/improving-depression-care-for-adults-with-serious-mental-illness-in-underresourced-areas-community-coalitions-versus-technical-support
#18
Enrico G Castillo, Roderick Shaner, Lingqi Tang, Bowen Chung, Felica Jones, Yolanda Whittington, Jeanne Miranda, Kenneth B Wells
OBJECTIVE: Community Partners in Care (CPIC) was a group-randomized study of two approaches to implementing expanded collaborative depression care: Community Engagement and Planning (CEP), a coalition approach, and Resources for Services (RS), a technical assistance approach. Collaborative care networks in both arms involved health care and other agencies in five service sectors. This study examined six- and 12-month outcomes for CPIC participants with serious mental illness. METHODS: This secondary analysis focused on low-income CPIC participants from racial-ethnic minority groups with serious mental illness in underresourced Los Angeles communities (N=504)...
October 16, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/28984077/broad-clinical-high-risk-mental-state-charms-methodology-of-a-cohort-study-validating-criteria-for-pluripotent-risk
#19
Jessica A Hartmann, Barnaby Nelson, Rachael Spooner, G Paul Amminger, Andrew Chanen, Christopher G Davey, Meredith McHugh, Aswin Ratheesh, Devi Treen, Hok Pan Yuen, Patrick D McGorry
AIM: The development of the ultra-high risk (UHR) criteria for psychosis created a new paradigm for the prevention research in psychiatry. Since (1) prevention research faces the challenge of achieving adequate statistical power when focusing on single low-incidence syndromes and (2) early clinical phenotypes are overlapping and non-specific, this study broadens the UHR state beyond psychosis as an outcome. The CHARMS (clinical high at-risk mental state) study aims to prospectively validate a set of trans-diagnostic criteria to identify help-seeking young people at risk of developing a range of serious mental illnesses...
October 5, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/28981868/new-research-strategy-for-measuring-pre-and-postnatal-metal-dysregulation-in-psychotic-disorders
#20
Eva Velthorst, Lauren Smith, Ghalib Bello, Christine Austin, Chris Gennings, Amirhoessein Modabbernia, Nathalie Franke, Sophia Frangou, Robert Wright, Lieuwe de Haan, Abraham Reichenberg, Manish Arora
While previous studies have found evidence for detrimental effects of metals on neurodevelopment, the long-term effects on mental health remain unclear. The objective was to explore the effect of early metal exposure on risk of psychotic disorder and on symptom severity following illness onset. Through the use of validated tooth-biomarkers, we estimated pre- and postnatal exposure levels of essential elements (copper, magnesium, manganese, and zinc) and elements associated with neurotoxicity (lead, arsenic, lithium, and tin)...
October 21, 2017: Schizophrenia Bulletin
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