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https://www.readbyqxmd.com/read/28221337/modulation-of-digital-flexor-tendon-healing-by-vascular-endothelial-growth-factor-gene-transfection-in-a-chicken-model
#1
W F Mao, Y F Wu, Q Q Yang, Y L Zhou, J B Tang
A major challenge in tendon injury is the weak intrinsic healing capacity of tendon, which may cause re-rupture after surgery. Growth factors are believed to be critical during tendon healing. This study aimed to investigate the effects of vascular endothelial growth factor (VEGF) genes delivered by adeno-associated virus (AAV) vectors on tendon healing and molecular events involved in a chicken model. One hundred and twenty eight deep flexor tendons in the long toes of chickens were completely transected and injected with 2 × 10(9) particles of AAV2-VEGF or saline before surgically repaired...
February 21, 2017: Gene Therapy
https://www.readbyqxmd.com/read/28220191/anatomical-variations-of-flexor-hallucis-longus-tendon-increase-safety-in-hindfoot-endoscopy
#2
Jordi Vega, David Redó, Gabriela Savín, Francesc Malagelada, Miki Dalmau-Pastor
PURPOSE: The flexor hallucis longus (FHL) tendon is the main anatomical landmark during hindfoot endoscopy, and anatomical variations related to the FHL can pose a risk to the tibial nerve and posterior tibial vessels during hindfoot endoscopy. The aim of this study was to determine the distance between the FHL tendon and the tibial neurovascular bundle in the posterior ankle joint when an anatomical variant of the FHL is present. The hypothesis was that the shortest distance between the tibial neurovascular bundle and the FHL tendon in the working area of the hindfoot endoscopy is increased when an anatomical variant of the FHL is present...
February 20, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28219952/enthesis-regeneration-a-role-for-gli1-progenitor-cells
#3
Andrea G Schwartz, Leesa M Galatz, Stavros Thomopoulos
The tendon enthesis originates from a specific pool of hedgehog-active Gli1+ progenitor cells that differentiate and produce mineralized fibrocartilage. The current study investigated the regenerative capacity of this cell population by comparing the responses of early postnatal and mature entheses to injury. Lineage tracing studies demonstrated that the original Gli1+ cell population had the capacity to heal immature entheses after injury but this capacity was lost after the cells differentiated into mature fibrochondrocytes...
February 20, 2017: Development
https://www.readbyqxmd.com/read/28219360/interobserver-and-intraobserver-agreement-of-ligamentous-injuries-on-conventional-mri-after-simple-elbow-dislocation
#4
Marc Schnetzke, Svenja Schüler, Johannes Hoffend, Rainer Simon, Holger Keil, Felix Porschke, Stefan Studier-Fischer, Paul-Alfred Grützner, Thorsten Guehring
BACKGROUND: The primary objective of this study was to assess the interobserver and intraobserver agreement on ligamentous injuries on conventional magnetic resonance imaging (MRI) in acute simple elbow dislocation. The secondary objectives were to determine the interobserver agreement on the assessment of joint congruity, joint effusion, loose bodies and chondral lesions on conventional MRI. METHODS: Conventional MRIs (1.5 Tesla, elbow specific surface coil) of 30 patients (40...
February 20, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28217662/surgical-repair-of-isolated-triceps-tendon-rupture-using-a-suture-anchor-technique-a-case-report
#5
Federico Mancini, Gabriele Bernardi, Vincenzo DE Luna, Cosimo Tudisco
Rupture or avulsion of the distal triceps tendon is one of the least common tendon injuries. The most common clinical presentation of the injury is avulsion from the olecranon. The diagnosis of acute triceps tendon rupture may be missed and this can result in prolonged disability. We report the case of a 42-year-old man with isolated triceps rupture treated by an open surgical repair technique involving the use of bone suture anchors.
October 2016: Joints
https://www.readbyqxmd.com/read/28217566/single-and-dual-incision-technique-for-acute-distal-biceps-rupture-clinical-and-functional-outcomes
#6
Claudia Guglielmino, Paolo Massimino, Francesco Ioppolo, Sergio Castorina, Giuseppe Musumeci, Angelo Di Giunta
BACKGROUND: Distal bicep tendon injuries are a traumatic event though rather rare. The pathogenesis is not entirely clear. The most common cause for injury is an unexpected load on the biceps when the elbow is in an extended position. Although several studies have provided insight into the pathogenetic processes of the lesion, the literature suggests to treat all injuries surgically (whether partial or total) if there is high functional demand. METHODS: Between January 2006 and March 2016 were studied 20 patients surgically treated for a disconnected distal bicep, 15 with a total lesion and 5 with a partial lesion...
October 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28217565/therapeutic-use-of-hormones-on-tendinopathies-a-narrative-review
#7
REVIEW
Michele Abate, Matteo Guelfi, Andrea Pantalone, Daniele Vanni, Cosima Schiavone, Isabel Andia, Vincenzo Salini
BACKGROUND: Hormones can modify tendon homeostasis, some of them leading to tendon damage, while others are essentials for healing. This narrative review summarizes the current knowledge on the topic, focusing on the hormones normally secreted by endocrine glands. METHODS: A search in PubMed, Web of Knowledge and EMBASE, using the terms tendinopathy or tendon, combined with estrogens, testosterone, thyroid and parathyroid hormones, glucocorticoids and growth hormone, independently, was performed...
October 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28217216/repair-of-double-head-pectoralis-major-tendon-avulsion-into-its-native-footprint-using-bi-cortical-endobuttons-and-tendon-sliding-technique
#8
Jagadish Prabhu, Mohammed Khalid Faqi, Fahad Alkhalifa, Bader Kamal Tayara, Rashad Khamis Awad
Injuries to the pectoralis major muscle are relatively infrequent. The mechanism of injury is usually an eccentric shortening of the pectoralis major under heavy load, such as when performing a bench press exercise. We report a case that presented to us with a history of sudden pain in the left pectoral region while doing heavy bench press exercise. The patient sustained a type III D pectoralis muscle -tendon avulsion. Surgical repair was done through a bi-cortical tendon sliding technique using two cortical buttons...
2017: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/28216811/silicone-foley-s-catheter-as-an-effective-alternative-to-hunter-s-rod-in-staged-flexor-tendon-reconstruction-of-the-hand
#9
Tawheed Ahmad, Sheikh Adil Bashir, Mohammad Inam Zaroo, Adil Hafeez Wani, Saima Rashid, Summaira Jan
CONTEXT: Staged flexor tendon reconstruction is most suitable treatment method for extensive zone II tendon injuries. The Hunter's rod used in this procedure is costly and not easily available, which adds to the miseries of both patients as well as treating surgeon. AIMS: The aim of this study is to evaluate the results of staged zone II flexor tendon repair using silicone Foley's catheter as a cheaper and readily available alternative to Hunter's rod. SETTINGS AND DESIGN: This was a prospective study...
September 2016: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/28216305/severe-functional-debilitations-after-complications-associated-with-acute-achilles-tendon-rupture-with-9%C3%A2-years-of-follow-up
#10
Kristoffer Weisskirchner Barfod, Thor Magnus Sveen, Ann Ganestam, Lars Bo Ebskov, Anders Troelsen
The purpose of the present study was to investigate the long-term effect of deep infection, sural nerve injury, and repeat rupture in the treatment of acute Achilles tendon rupture. A total of 324 patients had made a claim to the Danish Patient Insurance Association from 1992 to 2010 for a complication after acute Achilles tendon rupture. Of the 324 patients, 119 (77 males and 42 females) returned the Achilles tendon total rupture score and the 36-item short-form survey questionnaires. Patients with deep infection (n = 10), sural nerve injury (n = 10), and repeat rupture (n = 16) participated in a follow-up investigation...
February 16, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28214472/bmp-12-activates-tenogenic-pathway-in-human-adipose-stem-cells-and-affects-their-immunomodulatory-and-secretory-properties
#11
Weronika Zarychta-Wiśniewska, Anna Burdzinska, Agnieszka Kulesza, Kamila Gala, Beata Kaleta, Katarzyna Zielniok, Katarzyna Siennicka, Marek Sabat, Leszek Paczek
BACKGROUND: Cell-based therapy is a treatment method in tendon injuries. Bone morphogenic protein 12 (BMP-12) possesses tenogenic activity and was proposed as a differentiating factor for stem cells directed to transplantation. However, BMPs belong to pleiotropic TGF-β superfamily and have diverse effect on cells. Therefore, the aim of this study was to determine if BMP-12 induces tenogenic differentiation of human adipose stem cells (hASCs) and how it affects other features of this population...
February 18, 2017: BMC Cell Biology
https://www.readbyqxmd.com/read/28214455/dorsal-plating-of-distal-radius-fractures-historical-context-and-appropriate-use
#12
Omri Ayalon, Nader Paksima
The management of distal radius fractures has evolved over time from a largely nonoperative paradigm to a more commonly performed operative procedures today. Surgical trends have similarly developed, with dorsal plating falling out of favor due to complications involving extensor tendon pathology as well as due to the ubiquity of the volar plate along with the advent of locking plate technology. However, with the improvement in design of newer generation dorsal plates, this technique should be used in the appropriate clinical situation, including dorsal comminution and angulation with concomitant carpal pathology...
January 2017: Bulletin of the Hospital for Joint Diseases
https://www.readbyqxmd.com/read/28211842/assessment-of-upper-limb-musculoskeletal-pain-and-posture-in-workers-of-packaging-units-of-pharmaceutical-industries
#13
Yasser Labbafinejad, Hossein Danesh, Zahra Imanizade
BACKGROUND: Work-related musculoskeletal disorders are defined as the disabling or painful injury to the muscles, nerves or tendons that are caused by work or aggravated by it. Some studies confirm the association between working in packaging units in various industries and the pain in the upper limb, but also there are controversies about the possible risk factors among different working populations. OBJECTIVE: The present study aims to define the potential ergonomic risk factors for musculoskeletal pain in the upper limb...
February 17, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28211591/magnetic-resonance-imaging-of-the-knee-an-overview-and-update-of-conventional-and-state-of-the-art-imaging
#14
Nicholas C Nacey, Matthew G Geeslin, Grady Wilson Miller, Jennifer L Pierce
: Magnetic resonance imaging (MRI) has become the preferred modality for imaging the knee to show pathology and guide patient management and treatment. The knee is one of the most frequently injured joints, and knee pain is a pervasive difficulty that can affect all age groups. Due to the diverse pathology, complex anatomy, and a myriad of injury mechanisms of the knee, the MRI knee protocol and sequences should ensure detection of both soft tissue and osseous structures in detail and with accuracy...
February 17, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28210648/utilization-of-platelet-rich-plasma-for-musculoskeletal-injuries-an-analysis-of-current-treatment-trends-in-the-united-states
#15
Joanne Y Zhang, Peter D Fabricant, Chad R Ishmael, Jeffrey C Wang, Frank A Petrigliano, Kristofer J Jones
BACKGROUND: Platelet-rich plasma (PRP) has emerged as a popular biologic treatment for musculoskeletal injuries and conditions. Despite numerous investigations on the efficacy of PRP therapy, current utilization of this treatment within the United States is not widely known. PURPOSE: To investigate the national utilization of PRP, including the incidence and conditions for which it is used in the clinical setting, and to determine the current charges associated with this treatment...
December 2016: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28206959/association-of-polymorphisms-rs1800012-in-col1a1-with-sports-related-tendon-and-ligament-injuries-a-meta-analysis
#16
REVIEW
Chunguang Wang, Hao Li, Kang Chen, Bing Wu, Haifeng Liu
It has been reported that the single nucleotide polymorphism (SNP) rs1800012 in COL1A1 might be associated with the susceptibility to sports-related tendon and ligament injuries such as ACL injuries, Achilles tendon injuries, shoulder dislocations and tennis elbow. But the data from different studies have been conflicting. Here we attempted to systematically summarize and clarify the association between the SNP and sports-related tendon and ligament injuries risk. Six eligible studies including 933 cases and 1,381 controls were acquired from PubMed, Web Of Science and Cochrane library databases...
February 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28205487/a-novel-surgical-technique-for-chronic-mallet-finger-injury-a-case-report
#17
Taku Suzuki, Naoto Inaba, Kazuki Sato
A 39-year-old man injured his left little finger and was diagnosed with chronic tendon mallet with -50° of extension and 80° of flexion at the DIP joint. We performed an anatomical reconstruction of the terminal tendon and both lateral bands with divided palmaris longus tendon grafting. Postoperative range of motion at the DIP joint improved to -5° of extension with no flexion loss. We demonstrated a novel surgical technique for chronic tendon mallet injury that might represent a useful choice for the treatment of chronic mallet finger injury...
March 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28205480/extensor-tendon-instability-due-to-sagittal-band-injury-in-a-martial-arts-athlete-a-case-report
#18
Andrew Kochevar, Ghazi Rayan
A Taekwondo participant sustained a hand injury from punching an opponent that resulted in painful instability of the ring finger extensor digitorum communis tendon due to sagittal band damage. His symptoms resolved after reconstructive surgery on the sagittal band (SB) with stabilization of the extensor tendon over the metacarpophalangeal joint.
March 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28205479/finger-trauma-due-to-surfing-a-case-series-and-analysis-of-fracture-patterns
#19
A C J Ruijs, L C Langenberg, J Rezzouk
BACKGROUND: The purpose of this study is to research the type of lesions to the hand and fingers in the sport of surfing. METHODS: All surfing related hand injuries reported to our hospital between January 2008 and September 2015 were analyzed. RESULTS: Thirty-seven patient files held a clear description of a trauma related to the surf sport. We found three finger sprains, five wounds needing suture, including one digital nerve lesion and one ring finger with flexor tendon injury, three fingertip amputations and twenty-six digital fractures...
March 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28205469/valgus-instability-of-the-elbow-due-to-medial-epicondyle-nonunion-treatment-by-fragment-excision-and-medial-collateral-ligament-reconstruction
#20
Yasunori Kaneshiro, Noriaki Hidaka, Koichi Yano, Makoto Fukuda, Hideki Sakanaka
BACKGROUND: The medial epicondyle nonunion becomes symptomatic valgus instability with medial elbow pain and joint instability due to dysfunction of the medial collateral ligament (MCL), thus requiring surgical treatment. The purpose of the present study is to report the clinical result of the fragment excision and ligament reconstruction by free tendon graft in the treatment of symptomatic medial epicondyle nonunion. METHODS: A retrospective study of five consecutive patients was performed...
March 2017: Journal of Hand Surgery Asian-Pacific Volume
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