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https://www.readbyqxmd.com/read/28646767/enhanced-photodegradation-of-2-4-dichlorophenoxyacetic-acid-using-a-novel-tio2-mgfe2o4-core-shell-structure
#1
Bui The Huy, Da-Som Jung, Nguyen Thi Kim Phuong, Yong-Ill Lee
A novel TiO2@MgO-Fe2O3 core-shell structure has been synthesized via a hydrolysis and co-precipitation method followed by calcination at 500 °C and has proven to be an efficient photocatalyst. The obtained TiO2@MgO-Fe2O3 core-shell was characterized by scanning electron microscopy, X-ray diffraction, and UV-Vis diffused reflectance techniques. Its photocatalytic activity toward 2,4-dichlorophenoxyacetic acid (2,4-D) was investigated in aqueous solutions with and without visible light irradiation in the presence and absence of hydrogen peroxide...
June 17, 2017: Chemosphere
https://www.readbyqxmd.com/read/28646743/analysis-of-ictal-magnetoencephalography-using-gradient-magnetic-field-topography-gmft-in-patients-with-neocortical-epilepsy
#2
Hiroshi Shirozu, Akira Hashizume, Hiroshi Masuda, Yosuke Ito, Yoko Nakayama, Takefumi Higashijima, Masafumi Fukuda, Shigeki Kameyama
OBJECTIVE: We aimed to validate the usefulness of gradient magnetic-field topography (GMFT) for analysis of ictal magnetoencephalography (MEG) in patients with neocortical epilepsy. METHODS: We identified 13 patients presenting with an ictal event during preoperative MEG. We applied equivalent current dipole (ECD) estimation and GMFT to detect and localize the ictal MEG onset, and compared these methods with the ictal onset zone (IOZ) derived from chronic intracranial electroencephalography...
June 7, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28646742/image-analysis-for-tsh-mrna-in-situ-hybridization-in-pituitary-glands-from-rats-with-thyroid-follicular-cell-hypertrophy-after-treatment-with-three-different-test-compounds
#3
Juergen Funk, Martin Ebeling, Thomas Singer, Christian Landes
The goal of this in situ hybridization and image analysis technique is to study the effects of new pharmacological/chemical entities on the thyroid and pituitary gland in rats, reveal the pathogenesis of thyroid follicular cell hypertrophy and to retrospectively exclude the risk of thyroid tumor development in humans. In the present study, we describe the increase of thyroid-stimulating hormone- (TSH-) beta subunit mRNA in the pars distalis of the pituitary gland and the quantitative measurement of TSH mRNA positive cells from rats of three 4-week toxicity studies treated with three different test compounds inducing thyroid follicular cell and hepatocellular hypertrophy in rats...
June 11, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28646629/mechanisms-of-inhibitory-effects-of-polycyclic-aromatic-hydrocarbons-in-the-photosynthetic-primary-processes-in-pea-leaves-and-thylakoid-preparations
#4
V D Kreslavski, M Brestic, S K Zharmukhamedov, V Yu Luybimov, A V Lankin, A Jajoo, S I Allakhverdiev
Inhibitory effects of Polycyclic aromatic hydrocarbons on plants is studied in pea leaves in order to elucidate the mechanisms of action of polycyclic aromatic hydrocarbons (PAHs) such as naphthalene (Naph) and phenanthrene (Phen) on activity of photosystem 2 (PS-2). The changes in different Chl fluorescence parameters were calculated on the basis of Chl fluorescence induction curves. Hydrogen peroxide content was measured in leaf homogenates by luminol-dependent chemiluminescence method. We demonstrated that due to PAH treatment, the total energy dissipation (DI0 /ABS) and amount of QB -non-reducing complexes of PS-2 significantly increased...
June 24, 2017: Plant Biology
https://www.readbyqxmd.com/read/28646589/new-promising-method-for-the-challenging-synthesis-of-5-acyl-2-amino-3-cyanothiophenes-chemisry-and-fluorescent-properties
#5
Kseniya I Lugovik, Alexander K Eltyshev, Enrico Benassi, Nataliya P Belskaya
Independent of the substrate structure and reaction conditions, 2-cyano-3-aminothioacrilonitriles, which contains two active electrophilic centers, were shown to interact with various active halo methylene compounds under mild conditions to afford 5-acyl-2-amino-3-cyanothiophenes as the only products. A series of new polyfunctional thiophene derivatives with a rare combination of functionalities were synthesized and their photophysical properties were experimentally and computationally investigated. The calculated electronic characteristics of the ground and excited states were compared to the experimental results, which provided a good understanding of the relationship between the optoelectronic properties and the molecular structures...
June 24, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/28646580/biosimilars-for-psoriasis-worldwide-overview-of-regulatory-guidelines-uptake-and-implications-for-dermatology-clinical-practice
#6
REVIEW
A D Cohen, J J Wu, L Puig, S Chimenti, R Vender, M Rajagopalan, R Romiti, C de la Cruz, L Skov, C Zachariae, H S Young, P Foley, J M van der Walt, L Naldi, A Blauvelt
The introduction of biologic drugs for the treatment of patients with psoriasis has revolutionized treatment paradigms and enabled numerous patients to achieve disease control with an acceptable safety profile. However, the high cost of biologics limits access to these medications for the majority of patients worldwide. In recent years, the introduction of biosimilars for inflammatory diseases has become a fast evolving field. The future use of biosimilars offers the potential for decreased cost and increased access to biologic drugs for patients with psoriasis...
June 24, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28646574/a-novel-habitat-based-approach-to-predict-impacts-of-marine-protected-areas-on-fishers
#7
João B Teixeira, Rodrigo L Moura, Morena Mills, Carissa Klein, Christopher J Brown, Vanessa M Adams, Hedley Grantham, Matthew Watts, Deborah Faria, Gilberto M Amado-Filho, Alex C Bastos, Reinaldo Lourival, Hugh P Possingham
While marine protected areas (MPAs) can simultaneously contribute to biodiversity conservation and fisheries management, the global network is biased towards particular ecosystem types, as it was largely established in an ad hoc fashion. The optimization of trade-offs between biodiversity benefits and socio-economic values increases implementation success and minimizes enforcement costs in the long run, but is often neglected in marine spatial planning (MSP). Although the acquisition of spatially explicit socioeconomic data is often perceived as a costly/secondary step in MSP, it is critical to account for lost opportunities by people whose activities will be restricted, especially fishers...
June 24, 2017: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/28646518/comparative-proteomics-and-protein-profile-related-to-phenolic-compounds-and-antioxidant-activity-in-germinated-oryza-sativa-kdml105-and-thai-brown-rice-mali-dang-for-better-nutritional-value
#8
Sarunyaporn Maksup, Sarintip Pongpakpian, Sittiruk Roytrakul, Suriyan Cha-Um, Kanyaratt Supaibulwatana
BACKGROUND: Brown rice (BR) and germinated brown rice (GBR) are considered as a prime source of carbohydrate and bioactive compounds for more than half of the world's populations. Several studies have reported on the proteomics of BR and GBR; however, the proteomic profiles related to the synthesis of bioactive compounds are less well documented. In this study, BR and GBR were used in a comparative analysis of the proteomic and bioactive compound profiles for two famous Thai rice varieties, Khao Dawk Mali 105 (KDML) and Mali Dang (MD)...
June 24, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28646435/eco-friendly-synthesis-of-silver-nanoparticles-using-green-algae-caulerpa-serrulata-reaction-optimization-catalytic-and-antibacterial-activities
#9
Eman F Aboelfetoh, Rania A El-Shenody, Mohamed M Ghobara
Stable colloidal silver nanoparticles (AgNPs) were synthesized using Caulerpa serrulata (green marine algae) aqueous extract as an efficient reducing and stabilizing agent. This method is considered to be a sustainable alternate to the more complicated chemical procedures. To achieve the optimization synthesis of AgNPs, several effects such as extract concentration, contact time, pH values, and temperature were examined. The synthesized AgNPs were characterized by UV-Vis spectroscopy, FT-IR, XRD, and HR-TEM...
July 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28646247/sucrose-octaacetate-chemical-kinetics-and-shelf-lives-at-various-formulation-phs
#10
Shalini Gaddam, William C Stagner
Developing pediatric friendly dosage forms is a high priority worldwide. Sucrose octaacetate (SOA) has been recommended for use as a surrogate for bitter tasting active pharmaceutical ingredients. Even though SOA has found a number of human use applications and has been employed for decades, there are no rigorous chemical kinetic studies reported. A recently reported SOA stability-indicating method was used to perform SOA chemical kinetic and stability studies. As part of the chemical kinetic study, reaction order, activation energies, extrapolated rate constants, pH-rate profiles at 4 and 25°C, and estimated shelf lives at 4 and 25°C at different buffer pHs are provided...
June 23, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28646193/fabrication-of-nitrogen-doped-nano-onions-and-their-electrocatalytic-activity-toward-the-oxygen-reduction-reaction
#11
E Y Choi, C K Kim
Nitrogen-doped nano-onions (NNO) were prepared as electrocatalytic materials for the oxygen reduction reaction (ORR). The nano-onions (NO), spherical graphitic material particles, were prepared by pyrolysis of nanodiamonds (ND). Oxidized NO (ONO) was prepared from NO by a modified Hummers' method, and this was mixed with urea, followed by pyrolysis, resulting in the formation of NNO. The nitrogen content and molar ratio of nitrogen-containing groups in the NNOs were varied by controlling the oxygen content of ONO to explore the effect of nitrogen content on the ORR activity...
June 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28646119/rest-suppression-mediates-neural-conversion-of-adult-human-fibroblasts-via-microrna-dependent-and-independent-pathways
#12
Janelle Drouin-Ouellet, Shong Lau, Per Ludvik Brattås, Daniella Rylander Ottosson, Karolina Pircs, Daniela A Grassi, Lucy M Collins, Romina Vuono, Annika Andersson Sjöland, Gunilla Westergren-Thorsson, Caroline Graff, Lennart Minthon, Håkan Toresson, Roger A Barker, Johan Jakobsson, Malin Parmar
Direct conversion of human fibroblasts into mature and functional neurons, termed induced neurons (iNs), was achieved for the first time 6 years ago. This technology offers a promising shortcut for obtaining patient- and disease-specific neurons for disease modeling, drug screening, and other biomedical applications. However, fibroblasts from adult donors do not reprogram as easily as fetal donors, and no current reprogramming approach is sufficiently efficient to allow the use of this technology using patient-derived material for large-scale applications...
June 23, 2017: EMBO Molecular Medicine
https://www.readbyqxmd.com/read/28646033/implementing-a-reference-measurement-system-for-c-peptide-successes-and-lessons-learned
#13
Randie R Little, Robert I Wielgosz, Ralf Josephs, Tomoya Kinumi, Akiko Takatsu, Hongmei Li, Daniel Stein, Chris Burns
BACKGROUND: Assessment of endogenous insulin secretion by measuring C-peptide concentrations is widely accepted. Recent studies have shown that preservation of even small amounts of endogenous C-peptide production in patients with type 1 diabetes reduces risks for diabetic complications. Harmonization of C-peptide results will facilitate comparison of data from different research studies and later among clinical laboratory results at different sites using different assay methods. CONTENT: This review provides an overview of the general process of harmonization and standardization and the challenges encountered with implementing a reference measurement system for C-peptide...
June 23, 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/28646012/scatter-correction-with-combined-single-scatter-simulation-and-monte-carlo-simulation-scaling-improved-the-visual-artifacts-and-quantification-in-3d-brain-pet-ct-imaging-with-15-o-gas-inhalation
#14
Keiichi Magota, Tohru Shiga, Yukari Asano, Daiki Shinyama, Jinghan Ye, Amy E Perkins, Piotr J Maniawski, Takuya Toyonaga, Kentaro Kobayashi, Kenji Hirata, Chietsugu Katoh, Naoya Hattori, Nagara Tamaki
In three-dimensional positron emission tomography (PET)/computed tomography (CT) imaging of the brain with (15)O-gas inhalation, high radioactivity in the face mask creates cold artifacts and affects the quantitative accuracy when scatters is corrected by conventional methods (e.g., single-scatter simulation [SSS] with tail-fitting scaling [TFS-SSS]). Here we examined the validity of a newly developed scatter correction method that combines SSS with a scaling factor calculated by Monte Carlo simulation (MCS-SSS)...
June 23, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28645969/protocol-for-the-residents-in-action-pilot-cluster-randomised-controlled-trial-riat-evaluating-a-behaviour-change-intervention-to-promote-walking-reduce-sitting-and-improve-mental-health-in-physically-inactive-older-adults-in-retirement-villages
#15
Cecilie Thøgersen-Ntoumani, Ashlene Wright, Eleanor Quested, Elissa Burton, Keith D Hill, Ester Cerin, Stuart J H Biddle, Nikos Ntoumanis
INTRODUCTION: Ageing is accompanied by increased risks of chronic disease, declined functioning and increased dependency. Physical activity is critical to retaining health and independence, but the majority of older people are insufficiently physically active to achieve these benefits and have high levels of sedentary (sitting) time. Activity programmes are often offered in retirement villages; however, their uptake is limited. Furthermore, although the physical environment in and around these villages can play an important role in decisions to be physically active, its role is often overlooked by research in these settings...
June 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28645965/the-perspective-of-european-researchers-of-national-occupational-safety-and-health-institutes-for-contributing-to-a-european-research-agenda-a-modified-delphi-study
#16
Diana Gagliardi, Bruna M Rondinone, Marco Mirabile, Giuliana Buresti, Peter Ellwood, Michel Hery, Peter Paszkiewicz, Antonio Valenti, Sergio Iavicoli
OBJECTIVES: This study, developed within the frame of the Partnership for European Research on Occupational Safety and Health joint research activities and based on the frame designed by the 2013 European Agency for Safety and Health at Work (EU-OSHA) study, is the first example of using the points of view of European occupational safety and health (OSH) researchers.The objective is to identify priorities for OSH research that may contribute to the achievement of present and future sustainable growth objectives set by the European strategies...
June 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28645844/modelling-and-interpreting-mesoscale-network-dynamics
#17
REVIEW
Ankit N Khambhati, Ann E Sizemore, Richard F Betzel, Danielle S Bassett
Recent advances in brain imaging techniques, measurement approaches, and storage capacities have provided an unprecedented supply of high temporal resolution neural data. These data present a remarkable opportunity to gain a mechanistic understanding not just of circuit structure, but also of circuit dynamics, and its role in cognition and disease. Such understanding necessitates a description of the raw observations, and a delineation of computational models and mathematical theories that accurately capture fundamental principles behind the observations...
June 20, 2017: NeuroImage
https://www.readbyqxmd.com/read/28645775/altered-populations-of-natural-killer-cells-cytotoxic-t-lymphocytes-and-regulatory-t-cells-in-major-depressive-disorder-association-with-sleep-disturbance
#18
Hideo Suzuki, Jonathan Savitz, T Kent Teague, Siva K Gandhapudi, Chibing Tan, Masaya Misaki, Brett A McKinney, Michael R Irwin, Wayne C Drevets, Jerzy Bodurka
A subset of individuals with major depressive disorder (MDD) have impaired adaptive immunity characterized by a greater vulnerability to viral infection and a deficient response to vaccination along with a decrease in the number and/or activity of T cells and natural killer cells (NKC). Nevertheless, it remains unclear which specific subsets of lymphocytes are altered in MDD, a shortcoming we address here by utilizing an advanced fluorescence-activated cell sorting (FACS) method that allows for the differentiation of important functionally-distinct lymphocyte sub-populations...
June 20, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28645765/chitosan-surface-modified-electrospun-poly-%C3%AE%C2%B5-caprolactone-carbon-nanotube-composite-fibers-with-enhanced-mechanical-cell-proliferation-and-antibacterial-properties
#19
Siyu Wang, Yumei Li, Rui Zhao, Toufeng Jin, Li Zhang, Xiang Li
The surface modification is one of the most effective methods to improve the bioactivity and cell affinity effect of electrospun poly(ε-caprolactone) (PCL) fibers. In the present study, chitosan (CS), a cationic polysaccharide, was used to modify the surface of electrospun PCL fibers. To obtain strong interaction between CS and PCL fibers, negatively charged PCL fibers were prepared by the incorporation of acid-treated carbon nanotubes (CNTs) into the fibers. In this way, the positively charged chitosan could be immobilized onto the surface of PCL fibers tightly by the electrostatic attraction...
June 20, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28645650/isolation-identification-and-biocontrol-of-antagonistic-bacterium-against-botrytis-cinerea-after-tomato-harvest
#20
Jun-Feng Shi, Chang-Qing Sun
Tomato is one of the most important vegetables in the world. Decay after harvest is a major issue in the development of tomato industry. Currently, the most effective method for controlling decay after harvest is storage of tomato at low temperature combined with usage of chemical bactericide; however, long-term usage of chemical bactericide not only causes pathogen resistance but also is harmful for human health and environment. Biocontrol method for the management of disease after tomato harvest has great practical significance...
June 3, 2017: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
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