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Allergic rhinitis and comorbidities

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https://www.readbyqxmd.com/read/29909507/what-is-the-relationship-between-eosinophilic-esophagitis-eoe-and-aeroallergens-implications-for-allergen-immunotherapy
#1
REVIEW
Maureen Egan, Dan Atkins
PURPOSE OF REVIEW: Observations suggesting that aeroallergens trigger eosinophilic esophagitis (EoE) in a subset of patients raise questions about the implications this finding has on the evaluation and management of patients with EoE, including a potential role for allergen immunotherapy. RECENT FINDINGS: The majority of studies evaluating the potential role of aeroallergens as provocateurs of EoE have addressed this issue by assessing the seasonal variation in EoE diagnosis and/or symptom onset or worsening, with mixed results...
June 16, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29908674/analysis-of-factors-associated-with-cedar-pollen-sensitization-and-development-of-pollinosis-in-a-young-japanese-adult-population
#2
Satoshi Nakamura, Sachiko Tsunoda, Hiroshi Sakaida, Sawako Masuda, Ahamad Shah Said, Kazuhiko Takeuchi
BACKGROUND: Genetic and environmental factors are proposed to be involved in cedar pollen allergy sensitization and onset. The impact of these factors will provide key information for the prevention of cedar pollen sensitization and allergy onset, which we investigated in this cross-sectional study. METHODS: Subjects were 382 young adult volunteers who completed a self-administered questionnaire on self-reported subjective symptoms of pollinosis, physician-diagnosed pollinosis, and background factors...
June 13, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29869791/precision-medicine-in-united-airways-disease-a-treatable-traits-approach
#3
REVIEW
Anthony Ca Yii, Tunn-Ren Tay, Xue Ning Choo, Mariko Sy Koh, Augustine Kh Tee, De-Yun Wang
United airways disease (UAD) is the concept that the upper and lower airways, which are anatomically and immunologically related, form a single organ. According to this concept, upper and lower airway diseases are frequently comorbid because they reflect manifestations of a single underlying disease at different sites of the respiratory tract. Allergic asthma-allergic rhinitis is the archetypal UAD, but emerging data indicate that UAD is a heterogeneous condition and consists of multiple phenotypes (observable clinical characteristics) and endotypes (pathobiologic mechanisms)...
June 5, 2018: Allergy
https://www.readbyqxmd.com/read/29798499/-analysis-of-the-related-factors-of-attention-deficit-hyperactivity-disorder-and-allergic-rhinitis-in-children
#4
Z Z Cao, X X Zheng, B H Feng, J J Gao, S Y Huang, X Zhan, B L Li, B B Chen
Objective: To investigate the association between symptom of attention deficit/hyperactivity disorder (ADHD) and allergic rhinitis (AR) in children with AR at different sexes and different ages. Method: A total of 439 AR children aged 6 to 12 years were enrolled in this study. Basic information (age, gender, medical history, family history and comorbidities) of children with AR was collected. Results of prick tests on children skin were recorded. (TNSS) and Chinese version of the SNAP-Ⅳ scale, children under the guidance of independent completion of children's quality of life of children with nasal conjunctivitis scale (PRQLQ)...
February 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29798211/-effects-of-nasal-polyps-and-allergy-rhinitis-on-quantitative-evaluation-of-subjective-and-objective-assessment-of-chronic-rhinosinusitis
#5
L H Chen, C G Liu, H Jiang
Objective: To investigate the effect of nasal polyps and allergy rhinitis on disease assessment of chronic rhinosinusitis, and to analyze the correlation between subjective and objective scores. Method: A total of 253 patients with chronic rhinosinusitis were enrolled from June 2016 to June 2017, and the clinical data such as sex, age, comorbidity, diagnosis and treatment were summarized. All patients were grouped as with or without nasal polyps, with or without eosinophilia, with or without allergic rhinitis group, and assessed by the visual analogue scale(VAS), Lund-Mackay CT score and Lund-Kennedy score respectively...
January 5, 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29771333/multiple-comorbid-conditions-sleep-quality-and-duration-and-academic-performance-in-urban-children-with-asthma
#6
Katharine C Reynolds, Julie Boergers, Sheryl J Kopel, Daphne Koinis-Mitchell
Objective: Common comorbid medical conditions including allergic rhinitis (AR), obesity, and sleep disordered breathing (SDB) have been linked with asthma exacerbations; however, these conditions also impact sleep and academic functioning. The current study sought to examine unique and combined associations of these common comorbidities on sleep and academic performance among urban minority children with persistent asthma. We expected additional comorbid diagnoses would be associated with poorer sleep and academic functioning...
May 15, 2018: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29748453/treatment-strategy-of-allergic-rhinitis-in-the-face-of-modern-world-threats
#7
Piotr Rapiejko, Dariusz Jurkiewicz, Wioletta Pietruszewska, Beata Zielnik-Jurkiewicz, Jarosław Woroń, Agnieszka Lipiec
Allergic rhinitis (AR) is the most common form of allergy, which - as epidemiological research has shown - applies to nearly 25% of the population. AR significantly affects the quality of life of the patient, and the more severe the disease, the greater the risk of developing bronchial asthma. One of the factors affecting the severity of symptoms and the degree of their control is air pollution. In some patients, despite proper treatment, persistence or only partial remission of symptoms (uncontrolled allergic rhinitis) is observed...
April 30, 2018: Otolaryngologia Polska
https://www.readbyqxmd.com/read/29663825/clustering-analysis-in-asthmatic-outpatients-an-experience-in-clinical-practice
#8
Giorgio Ciprandi, Michela Silvestri, Angela Pistorio, Fabio Luigi Massimo Ricciardolo
No abstract text is available yet for this article.
April 17, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29663342/associations-of-chronic-urticaria-with-atopic-and-autoimmune-comorbidities-a-nationwide-population-based-study
#9
Hsien-Yi Chiu, Chih-Hsin Muo, Fung-Chang Sung
BACKGROUND: Most cases of chronic urticaria (CU) are idiopathic. Circumstantial evidence suggests that some CU cases have an autoimmune pathogenesis. Previous research indicates that a substantial percentage of patients with CU have an atopic background. OBJECTIVES: This study aims to examine the association between CU, and atopic and autoimmune diseases. METHODS: This population-based retrospective cohort study identified 9,332 patients with CU and 37,328 controls matched for age, sex, and number of dermatological clinic visits from the Taiwan National Health Insurance Research Database for 2004-2009...
July 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29661187/incidence-and-risk-factors-for-recurrent-henoch-sch%C3%A3-nlein-purpura-in-children-from-a-16-year-nationwide-database
#10
Wei-Te Lei, Po-Li Tsai, Szu-Hung Chu, Yu-Hsuan Kao, Chien-Yu Lin, Li-Ching Fang, Shyh-Dar Shyur, Yu-Wen Lin, Shu-I Wu
BACKGROUND: The recurrence rate of Henoch-Schönlein purpura (HSP) is 2.7%-30%, with varied average intervals between the first and second episodes. Few studies have explored the incidence and risk factors for recurrent HSP. METHODS: We used a 16-year nationwide database to analyze the incidence of recurrent HSP. Patients with HSP were identified, and risk factors for recurrent HSP were explored. Kaplan-Meier and Cox regression model analyses were performed, and covariates were adjusted in the multivariate model...
April 16, 2018: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/29652870/surveillance-for-the-identification-of-cases-of-acute-respiratory-infection-by-enterovirus-d68-in-children-in-a-tertiary-level-care-hospital-during-2014-2016
#11
Ana Estela Gamiño-Arroyo, José Luis Sánchez-Huerta, Alicia Elhaín de la Garza-López, Israel Parra-Ortega, Noé Escobar-Escamilla, Edgar Mendieta-Condado, Fabiola Garcés-Ayala, Gisela Barrera-Badillo, José Ernesto Ramírez-González, José Alberto Díaz-Quiñonez, Daniela de la Rosa-Zamboni
Background: The reemergence of enterovirus D68 (EV-D68) infections in the United States was reported from August-October 2014 (691 cases). In Mexico, an outbreak at the National Institute of Respiratory Diseases was reported (24 cases). The results of epidemiological surveillance of Enterovirus sp. (EV) and other respiratory viruses in a national pediatric tertiary care level hospital are presented. Methods: Following the alert issued by the reemergence of EV-D68 in 2014, epidemiological surveillance -which only detected respiratory viruses by PCR in patients with influenza-like illness using nasopharyngeal swabs- expanded to include children with asthma exacerbation or acute respiratory distress...
2018: Boletín Médico del Hospital Infantil de México
https://www.readbyqxmd.com/read/29619134/type-b-adverse-drug-reactions-reported-by-an-immunoallergology-department
#12
Maria J Costa, Maria T Herdeiro, Jorge J Polónia, Inês Ribeiro-Vaz, Cármen Botelho, Eunice Castro, Josefina Cernadas
Objective: Characterization of the adverse drug reactions (ADR) reported by the immunoallergology department (IAD), Centro Hospitalar de São João (Porto), to the Northern Pharmacovigilance Centre (NPC). Methods: An observational, descriptive and retrospective study was conducted, based in a spontaneous report system. Participants were all the patients from the IAD, with suspected ADR, reported to NPC by specialists after the study was completed. Results: Studied population had a median age of 41 years, with the predominance of the female gender (73...
January 2018: Pharmacy Practice
https://www.readbyqxmd.com/read/29615844/bepotastine-besilate-ophthalmic-solution-1-5-for-alleviating-nasal-symptoms-in-patients-with-allergic-conjunctivitis
#13
Megan E Cavet, Paul J Gomes, Warner W Carr, Jon I Williams
Background: Bepotastine besilate ophthalmic solution (BBOS) 1.5% is a topical antihistamine for the treatment of ocular itching associated with allergic conjunctivitis (AC). Allergic rhinitis and AC are common comorbid conditions. We explored the efficacy of BBOS 1.5% in alleviating nasal symptoms in an integrated analysis of two Phase III conjunctival allergen challenge (CAC) studies and a Phase IV environmental allergen study. Methods: In the Phase III trials, a CAC was performed 15 minutes, 8 hours, and 16 hours following ocular instillation of BBOS 1...
2018: Journal of Asthma and Allergy
https://www.readbyqxmd.com/read/29567854/risk-factors-of-asthma-exacerbation-based-on-asthma-severity-a-nationwide-population-based-observational-study-in-south-korea
#14
Hye-Rim Kang, Hyun Jin Song, Jin Hyun Nam, Sung-Hyun Hong, So-Young Yang, SangEun Ju, Sang Won Lee, Tae-Bum Kim, Hye-Lin Kim, Eui-Kyung Lee
OBJECTIVES: Asthma exacerbation, associated with many risks factors, can reflect management failure. However, little is known about how risk factors are associated with exacerbation, according to asthma severity. We aimed to investigate differences in risk factors in patients with different asthma severity and evaluate whether risk factors differed between frequent exacerbators and patients with single exacerbation. DESIGN: Nationwide population-based observational study...
March 22, 2018: BMJ Open
https://www.readbyqxmd.com/read/29565188/safety-of-cetirizine-in-pregnancy
#15
Amanda Golembesky, Maureen Cooney, Rossen Boev, Anne-Françoise Schlit, Jürgen W G Bentz
Managing symptoms of allergic rhinitis (AR) and urticaria in pregnant women is important to reduce complications and negative outcomes. The objective of this study was to provide information on the pregnancy outcomes of women exposed to the antihistamine cetirizine (CTZ). The UCB Pharma Patient Safety Database was searched for pregnancies up to 28 February 2015. Maternal CTZ exposure reports were extracted, and pregnancy outcomes were examined, including exposure, comorbidities and infant events. 228 of 522 pregnancies with maternal CTZ exposure had available outcomes; 49 were prospective...
March 22, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29552874/allergic-conjunctivitis-current-concepts-on-pathogenesis-and-management
#16
M Sacchetti, I Abicca, A Bruscolini, C Cavaliere, M Nebbioso, A Lambiase
Allergic conjunctivitis (AC) includes a wide spectrum of clinical entities characterized by different incidence, age of onset, natural course, clinical outcome and response to treatment. Taken together, they represent one of the most frequent ocular surface diseases affecting more than 30% of the young-adult population and show an increasing incidence over the years. Moreover, comorbidities with other systemic atopic conditions such as asthma, atopic dermatitis and rhinitis require a multidisciplinary approach...
January 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29530123/-a-meta-analysis-of-risk-factors-for-asthma-in-chinese-children
#17
Shu-Jun Liu, Ting-Ting Wang, Shi-Yu Cao, Ya-Qing Tan, Li-Zhang Chen
OBJECTIVE: To investigate the main risk factors for asthma in Chinese children, and to provide a reference for the prevention and treatment of asthma. METHODS: The databases including CNKI, Wanfang Data, China Biology Medicine disc, VIP Database for Chinese Technical Periodicals, Web of Science, and PubMed were searched for studies on risk factors for asthma in Chinese children published up to September 2017. Stata 12.0 was used for the Meta analysis. RESULTS: A total of 24 case-control studies were included, with 5 309 cases in the case group and 6 404 cases in the control group...
March 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29518830/-a-follow-up-study-of-six-years-outcome-of-children-with-asthma-in-urban-area-of-beijing
#18
C Y Tian, L Sha, C H Liu, Y Q Luo, S Li, M Y Zhao, W Wang, Y Z Chen
Objective: To understand the outcome of asthma in children from urban area of Beijing and the factors associated with the outcome. Methods: A total of 497 children with asthma diagnosed in the epidemiological survey of childhood asthma in urban area of Beijing in 2010 were selected in this study. Telephone follow-up was conducted in 2016 to obtain information about asthma attack, emergency visit, hospitalization, medication and disease control, and data of comorbidities of allergic diseases from 1 year earlier...
March 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29501293/meta-analysis-of-the-comorbidity-rate-of-allergic-rhinitis-and-asthma-in-chinese-children
#19
Wei Kou, Xuelei Li, Hongbing Yao, Ping Wei
OBJECTIVES: Allergic rhinitis (AR) and asthma often occur concomitantly and are the two most common inflammatory conditions of the airways in children. Large-scale studies investigating the comorbidity of asthma and AR in children are rare. So, we performed a meta-analysis to describe the comorbidity rate of asthma and AR in Chinese children. METHODS: We retrieved related studies from Pubmed, Science, Springer, Elsevier, Embase, BMJ, and four Chinese biomedical databases, including Wanfang Data, VIP, CBM, and CNKI...
April 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29501247/the-impact-of-aging-on-outpatients-with-asthma-in-a-real-world-setting
#20
Giorgio Ciprandi, Irene Schiavetti, Fabio L M Ricciardolo
BACKGROUND: Asthma is characterized by airway inflammation and bronchial hyperreactivity. It is conceived that aging may affect asthma characteristics, but this issue is still not completely clarified in clinical practice. OBJECTIVE: The present study investigated whether aging may affect some clinical and functional factors in outpatients with asthma visited in a real-world setting, such as clinical practice. METHODS: Globally, 391 outpatients (163 males, median age 47 years) with asthma were consecutively evaluated...
March 2018: Respiratory Medicine
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