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Allergic rhinitis and comorbidities

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https://www.readbyqxmd.com/read/29470484/the-characteristic-of-asthma-control-among-nasal-diseases-population-results-from-a-cross-sectional-study
#1
Jiangtao Lin, Jie Gao, Kefang Lai, Xin Zhou, Bei He, Jianying Zhou, Changzheng Wang
Asthma affects a large number of patients in China, but comprehensive evaluation of risks associated with poor asthma control in asthmatic patients with nasal diseases was still limited. We conducted this study to provide a comprehensive estimate of asthma control in Chinese asthma patients with combined nasal diseases, to explore the effect of kinds of nasal diseases on the asthma control, and to identify risk factors associated with uncontrolled asthmatic patients with combined nasal diseases. 1756 asthma patients concomitant with nasal diseases aged ≥17 years and representing all regions of mainland China were surveyed...
2018: PloS One
https://www.readbyqxmd.com/read/29455359/eosinophilic-esophagitis-an-important-comorbid-condition-of-asthma
#2
REVIEW
Sandy R Durrani, Vincent A Mukkada, Theresa W Guilbert
Eosinophilic esophagitis and asthma are frequently found as comorbid conditions in children and adults along with other manifestations of atopic diathesis. These two conditions have similar T helper 2 responses-driven pathophysiology and share common management strategies such as using systemic corticosteroids and targeted anti-cytokine biologic therapies. Review of the literature finds that asthma is often a comorbid condition in eosinophilic esophagitis in both children and adults; however, the EoE-asthma relationship remains poorly characterized mechanistically and clinically...
February 18, 2018: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/29447897/pattern-of-allergic-rhinitis-among-children-in-ekiti-nigeria
#3
Waheed Atilade Adegbiji, Gabriel Toye Olajide, Anthony Oyebanji Olajuyin, Shuaib Kayode Aremu, Akanbi Ganiyu Olusola
BACKGROUND: Allergic rhinitis is a chronic and recurrent nasal condition. It is often neglected in children with late presentation. This study aimed at determining the prevalence, sociodemographic features, comorbid illnesses, complications and quality of life in children with allergic rhinitis in the study institution. MATERIALS AND METHODS: This is a prospective hospital based study of children with allergic rhinitis in Ekiti state university teaching hospital, Ado Ekiti...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29438602/international-consensus-statement-on-allergy-and-rhinology-allergic-rhinitis
#4
Sarah K Wise, Sandra Y Lin, Elina Toskala, Richard R Orlandi, Cezmi A Akdis, Jeremiah A Alt, Antoine Azar, Fuad M Baroody, Claus Bachert, G Walter Canonica, Thomas Chacko, Cemal Cingi, Giorgio Ciprandi, Jacquelynne Corey, Linda S Cox, Peter Socrates Creticos, Adnan Custovic, Cecelia Damask, Adam DeConde, John M DelGaudio, Charles S Ebert, Jean Anderson Eloy, Carrie E Flanagan, Wytske J Fokkens, Christine Franzese, Jan Gosepath, Ashleigh Halderman, Robert G Hamilton, Hans Jürgen Hoffman, Jens M Hohlfeld, Steven M Houser, Peter H Hwang, Cristoforo Incorvaia, Deborah Jarvis, Ayesha N Khalid, Maritta Kilpeläinen, Todd T Kingdom, Helene Krouse, Desiree Larenas-Linnemann, Adrienne M Laury, Stella E Lee, Joshua M Levy, Amber U Luong, Bradley F Marple, Edward D McCoul, K Christopher McMains, Erik Melén, James W Mims, Gianna Moscato, Joaquim Mullol, Harold S Nelson, Monica Patadia, Ruby Pawankar, Oliver Pfaar, Michael P Platt, William Reisacher, Carmen Rondón, Luke Rudmik, Matthew Ryan, Joaquin Sastre, Rodney J Schlosser, Russell A Settipane, Hemant P Sharma, Aziz Sheikh, Timothy L Smith, Pongsakorn Tantilipikorn, Jody R Tversky, Maria C Veling, De Yun Wang, Marit Westman, Magnus Wickman, Mark Zacharek
BACKGROUND: Critical examination of the quality and validity of available allergic rhinitis (AR) literature is necessary to improve understanding and to appropriately translate this knowledge to clinical care of the AR patient. To evaluate the existing AR literature, international multidisciplinary experts with an interest in AR have produced the International Consensus statement on Allergy and Rhinology: Allergic Rhinitis (ICAR:AR). METHODS: Using previously described methodology, specific topics were developed relating to AR...
February 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29438600/international-consensus-statement-on-allergy-and-rhinology-allergic-rhinitis-executive-summary
#5
Sarah K Wise, Sandra Y Lin, Elina Toskala
BACKGROUND: The available allergic rhinitis (AR) literature continues to grow. Critical evaluation and understanding of this literature is important to appropriately utilize this knowledge in the care of AR patients. The International Consensus statement on Allergy and Rhinology: Allergic Rhinitis (ICAR:AR) has been produced as a multidisciplinary international effort. This Executive Summary highlights and summarizes the findings of the comprehensive ICAR:AR document. METHODS: The ICAR:AR document was produced using previously described methodology...
February 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29423374/the-international-study-of-the-allergic-rhinitis-survey-outcomes-from-4-geographical-regions
#6
Desiderio Passali, Cemal Cingi, Paola Staffa, Francesco Passali, Nuray Bayar Muluk, Maria Luisa Bellussi
Background: Allergic rhinitis (AR) is a global health problem and is characterised by one or more symptoms, including sneezing, itching, nasal congestion and rhinorrhea. Objective: We investigated the features of AR and the physician's approach to the management of AR patients in four geographical regions. Methods: In this cross-sectional study, a questionnaire survey concerning AR was completed by Honorary and Corresponding Members of the Italian Society of Rhinology from different countries among 4 world geographical regions-Asia, Europe, the Americas, and Africa...
January 2018: Asia Pacific Allergy
https://www.readbyqxmd.com/read/29423372/optimal-control-of-asthma-improved-eosinophilic-otitis-media
#7
Yukako Seo, Manabu Nonaka, Yukie Yamamura, Ruby Pawankar, Etsuko Tagaya
Background: Eosinophilic otitis media (EOM) is often associated with comorbid asthma. The middle ear cavity is part of the upper airway. Therefore, EOM and asthma can be considered to be a crucial part of the "one airway, one disease" phenomenon. Based on the concept of one airway, one disease in the context of allergic rhinitis and asthma, optimal level of inhalation therapy for better asthma control leads to improvement in allergic rhinitis. Objective: We conducted a pilot study to determine whether appropriate strengthening of inhalation therapy for asthma is effective for EOM...
January 2018: Asia Pacific Allergy
https://www.readbyqxmd.com/read/29417583/the-use-of-specific-immunoglobulin-e-in-nasal-secretions-for-the-diagnosis-of-allergic-rhinitis
#8
Yifan Meng, Hongfei Lou, Yang Wang, Chengshuo Wang, Luo Zhang
OBJECTIVE: Although local specific immunoglobulin (sIgE) has been employed as a diagnostic criterion for allergic rhinitis (AR), the use of local sIgE has not been fully evaluated in the diagnosis of allergic rhinitis. The aim of this study was to evaluate the use of nasal secretion sIgE in the diagnosis of allergic rhinitis. METHODS: A total of 51 patients (27 males and 24 females, mean age = 33.3 years) with rhinitis symptoms were enrolled consecutively from the allergy-rhinology clinic of Beijing TongRen Hospital (Beijing, People's Republic of China)...
February 8, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29401486/acute-and-chronic-rhinosinusitis-and-allergic-rhinitis-in-relation-to-comorbidity-ethnicity-and-environment
#9
Ruth Hoffmans, Alex Wagemakers, Cornelis van Drunen, Peter Hellings, Wytske Fokkens
BACKGROUND: This study was conducted to assess the effect of comorbidity, ethnicity, occupation, smoking and place of residence on allergic rhinitis (AR), acute rhinosinusitis (ARS) and chronic rhinosinusitis (CRS). METHODS: A GA2LEN (The Global Allergy and Asthma European Network) screening questionnaire was sent to a random sample of the Dutch population (n = 16700) in three different areas of the Netherlands. RESULTS: Fifty percent (8347) of the questionnaires sent were returned...
2018: PloS One
https://www.readbyqxmd.com/read/29384116/anaphylaxis-in-a-food-allergy-outpatient-department-one-year-review
#10
R A Fernandes, F Regateiro, C Pereira, E Faria, J Pita, A Todo-Bom, I Carrapatoso
Background. Anaphylaxis is an acute, potentially fatal, multi-organ allergic reac-tion. Our aim was to characterize the population with food induced anaphylaxis followed over a one-year period. Methods. Retrospective analysis of clinical files of patients with food anaphylaxis observed in our food allergy consultation during 2016. Results. Sixty-two patients were included. In the pediatric group, the implicated allergens were cow's milk, egg and fish and in the adults' group, the commonest allergens were nuts and wheat...
November 30, 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29355679/efficacy-and-safety-of-dupilumab-in-perennial-allergic-rhinitis-and-comorbid-asthma
#11
Steven F Weinstein, Rohit Katial, Shyamalie Jayawardena, Gianluca Pirozzi, Heribert Staudinger, Laurent Eckert, Vijay N Joish, Nikhil Amin, Jaman Maroni, Paul Rowe, Neil M H Graham, Ariel Teper
BACKGROUND: Dupilumab, an anti-IL-4Rα monoclonal antibody, inhibits IL-4/IL-13 signaling, key drivers of type 2/Th2 immune diseases (e.g. atopic/allergic disease). In a pivotal, phase 2b study (NCT01854047), dupilumab reduced severe exacerbations, improved lung function and quality of life, and was generally well tolerated in patients with uncontrolled persistent asthma despite using medium-to-high-dose inhaled corticosteroids plus long-acting β2-agonists. OBJECTIVE: To examine dupilumab's effect on the 22-item Sino-Nasal Outcome Test (SNOT-22) total score and its allergic rhinitis (AR)-associated items in asthma patients with comorbid perennial allergic rhinitis (PAR)...
January 17, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29350800/acquisition-remission-and-persistence-of-eczema-asthma-and-rhinitis-in-children
#12
Hongmei Zhang, Akhilesh Kaushal, Nelís Soto-Ramírez, Ali H Ziyab, Susan Ewart, John W Holloway, Wilfried Karmaus, Hasan Arshad
BACKGROUND: Allergic sensitization is associated with eczema, asthma, and rhinitis. However, it is unknown whether and how allergic sensitization is associated over time with acquisition, remission, and persistence of these diseases and their comorbidity. OBJECTIVE: To gain a better understanding of factors including allergic sensitization transitions that influence the temporal pattern of asthma, eczema, and rhinitis and their comorbidity during childhood. METHODS: In the Isle of Wight birth cohort information on allergic sensitization to common allergens was collected at ages 4, 10, and 18 years along with asthma, rhinitis, and eczema status determined by clinical diagnosis...
January 19, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29324857/allergic-rhinitis-and-rhinosinusitis-synergistically-compromise-the-mental-health-and-health-related-quality-of-life-of-korean-adults-a-nationwide-population-based-survey
#13
Ji-Hyeon Shin, Daeyoung Roh, Dong-Hee Lee, Soo Whan Kim, Sung Won Kim, Jin Hee Cho, Byung-Guk Kim, Boo-Young Kim
BACKGROUND: Allergic rhinitis (AR) and rhinosinusitis (RS) negatively impact psychological well-being and health-related quality of life (HRQoL). However, few population-based studies have investigated the effects of these conditions on mental health and HRQoL. PURPOSE: To explore independent associations of AR and/or RS with mental health and HRQoL using data from the 2013-2015 Korea National Health and Nutrition Examination Survey (KNHANES). METHODS: The KNHANES is a nationwide cross-sectional survey of the non-institutionalized population of Korea...
2018: PloS One
https://www.readbyqxmd.com/read/29315741/association-between-allergic-diseases-and-ophthalmologic-diseases-including-cataracts-and-glaucoma-using-the-korean-national-health-and-nutrition-examination-survey-2010-2012-a-strobe-compliant-article
#14
Young Bok Lee, Ji Hyun Lee, Min Ji Kang, Jin Young Choi, Jin-Wou Kim, Dong Soo Yu, Kyung Do Han, Yong Gyu Park
This study investigated the association between allergic diseases and comorbid ophthalmologic diseases. We enrolled 14 776 participants who were at least 19 years of age. Multiple logistic regression analyses were used to evaluate the odds ratios for cataracts and glaucoma according to the presence of allergic diseases. Atopic dermatitis was not associated with the development of cataracts and glaucoma. However, asthma and allergic rhinitis were significantly associated with cataracts (hazard ratio [HR] = 1...
January 4, 2018: Journal of Dermatology
https://www.readbyqxmd.com/read/29301162/milbenallergie-im-hno-bereich-bedeutung-diagnostik-und-therapieoptionen
#15
Ludger Klimek, Moritz Gröger, Sven Becker
Allergic rhinitis (AR) affects ca. 20% of the population. Approximately one third of patients affected by AR are suffering from perennial rhinitis due to mite allergy. Perennial rhinitis is the form of the disease that is most frequently associated with other allergy-related comorbidities such as asthma and atopic dermatitis, sleep disorders, chronic sinusitis, eustachian tube dysfunction and others.The often non-specific symptoms and the insidious course may lead to misinterpretations in diagnosing the disease...
January 2018: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/29262484/-epidemiological-characteristics-and-relevant-factors-on-the-comorbidity-of-hyperactivity-behavior-and-allergic-diseases-in-preschool-children
#16
T T Weng, S Q Yan, H Cao, C L Gu, Y Q Xu, L L Ni, H H Tao, T Shao, F B Tao
Objective: To understand the epidemiological characteristics and relevant factors on the comorbidity of hyperactivity behavior and allergic disease among preschool children in urban areas of Ma'anshan city. Methods: During April 2014 to April 2015, 91 kindergartens over 3 years old were investigated. In the investigation, 16 439 questionnaires were distributed to parents, and 15 291 valid questionnaires were collected. Conners abbreviated symptom questionnaire (brief symptom questionnaire) was filled out by parents to assess the children's hyperactive behaviors...
December 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/29227362/comorbidity-of-airway-inflammatory-diseases-in-chemical-and-building-related-intolerance
#17
Anna-Sara Claeson, Hanna Andersson, Fredrik Wikdahl, Maj-Helen Nyback, Steven Nordin
OBJECTIVES: This study investigated comorbidity in chemical intolerance (CI) and building- related intolerance (BRI) with (i) chronic sinusitis, chronic obstructive pulmonary disease, allergic and non-allergic asthma and allergic rhinitis, and (ii) airway inflammatory symptoms. METHODS: Data from two population-based questionnaire surveys, the Västerbotten and Österbotten Environmental Health Studies was used. The participants were categorized as CI or BRI and referents, and binary logistic regression analysis was applied...
December 8, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29225773/is-there-a-sex-shift-in-prevalence-of-allergic-rhinitis-and-comorbid-asthma-from-childhood-to-adulthood-a-meta-analysis
#18
REVIEW
M Fröhlich, M Pinart, T Keller, A Reich, B Cabieses, C Hohmann, D S Postma, J Bousquet, J M Antó, T Keil, S Roll
Background: Allergic rhinitis and asthma as single entities affect more boys than girls in childhood but more females in adulthood. However, it is unclear if this prevalence sex-shift also occurs in allergic rhinitis and concurrent asthma. Thus, our aim was to compare sex-specific differences in the prevalence of coexisting allergic rhinitis and asthma in childhood, adolescence and adulthood. Methods: Post-hoc analysis of systematic review with meta-analysis concerning sex-specific prevalence of allergic rhinitis...
2017: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/29135514/prevalence-and-clinical-characteristics-of-local-allergic-rhinitis-to-house-dust-mites
#19
Yoo Seob Shin, Chang-Gyu Jung, Hae-Sim Park
PURPOSE OF REVIEW: Local allergic rhinitis (LAR) is a recently classified subtype of rhinitis defined by a nasal allergic response in patients without systemic evidence of atopy. Recent studies have reported the prevalence, clinical course, culprit allergens, diagnostic methods and treatment outcomes of LAR. The purpose of this review is to summarize the most relevant and updated scientific evidence for LAR, especially focusing on its prevalence and clinical characteristics. RECENT FINDINGS: LAR is found in a significant proportion (3...
November 14, 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29133326/risks-for-comorbidity-in-children-with-atopic-disorders-an-observational-study-in-dutch-general-practices
#20
David H J Pols, Arthur M Bohnen, Mark M J Nielen, Joke C Korevaar, Patrick J E Bindels
OBJECTIVE: This study aimed to investigate both atopic and non-atopic comorbid symptoms and diseases in children with physician-diagnosed atopic disorders (atopic eczema, asthma and allergic rhinitis). METHODS: All children aged 0-18 years listed in a nationwide primary care database (the Netherlands Institute for Health Services Research-Primary Care Database) with routinely collected healthcare data in 2014 were selected. Children with atopic disorders were matched on age and gender with non-atopic controls within the same general practice...
November 12, 2017: BMJ Open
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