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Meckel diverticulum, pathophysiology, complications

Xiang Wang, Kashish Dhawan, Jie Lin, Ashwini Satpathy, Ping Zhang, Guozhong Ji, Zhining Fan, Faming Zhang
The ileum generally works well, whereas Meckel's diverticulum (MD) has complications including bleeding, obstruction, intussusception, diverticulitis, and perforation. Our knowledge of the pathological features of the MD muscular layer and mucosa is limited. We report a rare case of giant MD that was diagnosed by double-balloon enteroscopy (DBE). The pathological features of the mucosa were evaluated by investigation for Helicobacter pylori; and the nuclear proliferation antigen Ki-67, the gastrointestinal cancer-associated biomarker TRAK1, synaptophysin, and neurofilament were used to precisely define the mucosa and neuronal and ganglion cell components...
April 2010: Clinical Journal of Gastroenterology
Abdulmalik Altaf, Hager Aref
INTRODUCTION: Meckel's diverticulum is the most common congenital anomaly of the small intestine. Common complications related to Meckel's diverticulum include hemorrhage, intestinal obstruction and inflammation. Acute large bowel obstruction is a rare complication of Meckel's diverticulum and in the presented case it is caused by volvulus. PRESENTATION OF CASE: We report a 39 year old female who presented with the diagnosis of a large bowel obstruction occurring as a result of cecal volvulus caused by adhesions of a perforated diverticulum...
2014: International Journal of Surgery Case Reports
Sathyaprasad Burjonrappa, Phue Khaing
INTRODUCTION: Meckel's diverticulum is the most common congenital anomaly of the gastrointestinal tract. Currently, for any incidentally discovered Meckel's diverticulum, the management approach is based on weighing the statistical odds of future complications against the risks of a diverticulectomy. MATERIALS AND METHODS: The temporal relationship between age at Meckel's diverticulectomy and the presence of ectopic epithelium was evaluated in our series. A meta-analysis of all reported recent literature on this condition was subsequently performed to evaluate the strength of the relationship between ectopic epithelium and symptomatic Meckel's diverticulum...
April 2014: Journal of Indian Association of Pediatric Surgeons
J G Albert, C Lübbert, A Surow, S Zeuzem
Diverticula of the small bowel are quite frequent (about 5 %), but being a differential diagnosis of abdominal complaints they may still be underdiagnosed. One reason for the low level of suspicion for a complication of small bowel diverticula might be that the small bowel was out of the gastroenterologists' focus until recently when small bowel endoscopy became available as a reliable and practical diagnostic tool. Diverticula of the jejunum and the ileum may lead to diverticulitis, abscess, obstruction, bleeding, and perforation...
July 2009: Zeitschrift Für Gastroenterologie
Raj Kumar Sharma, Vir Kumar Jain
The current work attempts to highlight the various life threatening complications of Meckel's diverticulum and to present the surgical strategies used in the emergency conditions so far in the form of a review of the works presented in the literature. Our aim behind this presentation is to cover the possible indications, methods, their complications and the outcome of these surgical techniques. For this, we made an extensive literature search using Google and Pubmed with the words-"Meckel's diverticulum", "Complications", "Management" and "Emergency surgery"...
2008: World Journal of Emergency Surgery: WJES
P M Steinwald, G D Trachiotis, I R Tannebaum
Intussusception secondary to an inverted Meckel's diverticulum is considered to be a rare occurrence. The pathophysiology of the disease process results in a complicated clinical picture of chronic abdominal pain, lower gastrointestinal bleeding, and recurrent obstructive symptoms that may lead to an unnecessary delay in diagnosis. A case of an inverted Meckel's diverticulum as a lead point for an ileocolic intussusception in an adult is presented. The methods of diagnosis and the salient concepts in the surgical management of intussusception are discussed...
November 1996: American Surgeon
F Mosimann
A patient underwent simultaneous abdominal aortic prosthetic replacement and resection of a Meckel diverticulum. He then developed faecaloid breath. Later reoperation for aorto-enteric fistula cured halitosis. We conclude in retrospect that faecaloid breath may herald a secondary aorto-enteric fistula. A pathophysiological mechanism is suggested and discussed.
1995: VASA. Zeitschrift Für Gefässkrankheiten
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