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Veterinary depression

Evelyn Walker, Cecily Moore, Patrick Shearer, Martina Jelocnik, Sankhya Bommana, Peter Timms, Adam Polkinghorne
BACKGROUND: Arthritis is an economically significant disease in lambs and is usually the result of a bacterial infection. One of the known agents of this disease is Chlamydia pecorum, a globally recognised livestock pathogen associated with several diseases in sheep, cattle and other hosts. Relatively little published information is available on the clinical, diagnostic and pathologic features of C. pecorum arthritis in sheep, hindering efforts to enhance our understanding of this economically significant disease...
2016: BMC Veterinary Research
L R Berghman
The relationship between animal welfare and the immune status of an animal has a complex nature. Indeed, the intuitive notion that "increased vigilance of the immune system is by definition better" because it is expected to better keep the animal healthy, does not hold up under scrutiny. This is mostly due to the fact that the immune system consists of 2 distinct branches, the innate and the adaptive immune system. While they are intimately intertwined and synergistic in the living organism, they are profoundly different in their costs, both in terms of performance and wellbeing...
September 1, 2016: Poultry Science
Adrian P Ybañez, Rochelle Haidee D Ybañez, Rex R Villavelez, Honey Pearl F Malingin, Dana Natasha M Barrameda, Sharmaine V Naquila, Shiella Mae B Olimpos
AIM: The study aimed to document the clinical and hematological observations of dogs found serologically positive for Ehrlichia canis and to identify parameters or factors that are associated with the disease with focus on the anemic and thrombocytopenic state of the infected dogs. MATERIALS AND METHODS: From 7 participating veterinary establishments, a total of 913 cases from 2003 to 2014 were initially assessed using inclusion criteria, including E. canis diagnosis by the attending veterinarian and the presence of ticks or history of infestation, thrombocytopenia, and/or anemia...
January 2016: Veterinary World
Steven Jason Crellin, Kenneth D Katz
Suicide attempt via sodium pentobarbital is uncommon. A 48-year-old woman with a history of depression and prior suicide attempt was found unresponsive by her veterinarian spouse near a syringe containing pink solution. Upon EMS' arrival, the patient was experiencing apnea, hypoxemia, and miotic pupils; her blood glucose level measured 73 mg/dL. She was bradycardic and administered atropine with transient improvement in heart rate and transported to an emergency department; 2 mg of intravenous naloxone was administered without effect...
2016: Case Reports in Emergency Medicine
Atsushi Tsukamoto, Kaho Uchida, Shizuka Maesato, Reiichiro Sato, Eiichi Kanai, Tomo Inomata
Representative inhalant anesthetic agent, isoflurane is commonly used during surgery in rats. However, isoflurane mediates relatively strong respiratory depression. In human and veterinary medicine, sedatives and analgesics are co-administered to complement the anesthetic action of inhalant anesthesia. The present study aimed to establish the novel balanced anesthesia that combines midazolam and butorphanol with isoflurane (MBI) in rats. Male Sprague Dawley rats were divided into 2 groups, and administered either isoflurane monoanesthesia or isoflurane with midazolam (2...
July 29, 2016: Experimental Animals
Hongxu Du, Shuaibing Zhang, Meiyun Song, Yixuan Wang, Ling Zeng, Yun Chen, Wen Xiong, Jingjing Yang, Fangke Yao, Yi Wu, Deyun Wang, Yuanliang Hu, Jiaguo Liu
Because polysaccharide and flavone ingredients display good antiviral activity, we developed a flavone/polysaccharide-containing prescription that would be effective against duck viral hepatitis (DVH) and investigated its hepatoprotective effects. Flavones were derived from Hypericum japonicum (HJF) (entire herb of Hypericum japonicum Thunb) and Salvia plebeia (SPF) (entire herb of Salvia plebeia R. Br.), and polysaccharides were derived from Radix Rehmanniae Recens (RRRP) (dried root of Rehmannia glutinosa Libosch)...
2016: PloS One
Heather N Fowler, Stacy M Holzbauer, Kirk E Smith, Joni M Scheftel
OBJECTIVE: To identify the scope of occupational hazards encountered by veterinary personnel and compare hazard exposures between veterinarians and technicians working in small and large animal practices. DESIGN: Cross-sectional survey. POPULATION: Licensed veterinarians and veterinary staff in Minnesota. PROCEDURES: A survey of Minnesota veterinary personnel was conducted between February 1 and December 1, 2012. Adult veterinary personnel working in clinical practice for > 12 months were eligible to participate...
January 15, 2016: Journal of the American Veterinary Medical Association
Luminita Sarbu, Barbara E Kitchell, Philip J Bergman
OBJECTIVES: A xenogeneic human tyrosinase DNA vaccine was developed for treatment of dogs with oral malignant melanoma (Oncept; Merial). No studies have evaluated the safety or efficacy of this vaccine in cats. The purpose of this study is to evaluate the safety of the canine melanoma vaccine in cats diagnosed with melanoma. METHODS: Medical records were reviewed from cats diagnosed with malignant melanoma and treated with the canine melanoma DNA vaccine (Oncept)...
December 18, 2015: Journal of Feline Medicine and Surgery
Gareth E Zeiler, George F Stegmann, Geoffrey Fosgate, Roxanne K Buck, Sabine B R Kästner, Maya Kummrow, Christina Gerlach, Leith C R Meyer
There is a growing necessity to perform long-term anesthesia in wildlife, especially antelope. The costs and logistics of transporting wildlife to veterinary practices make surgical intervention a high-stakes operation. Thus there is a need for a field-ready total intravenous anesthesia (TIVA) infusion to maintain anesthesia in antelope. This study explored the feasibility of an etorphine-ketamine-medetomidine TIVA for field anesthesia. Ten wild-caught, adult impala ( Aepyceros melampus ) were enrolled in the study...
December 2015: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
Y Abba, F F J Abdullah, N H Bin Abu Daud, R Bin Shaari, A Tijjani, M A Sadiq, K Mohammed, L Adamu, A M L Mohd
A Boer-Kajang cross male goat was presented to the Veterinary Hospital, University Malaysia Kelantan with a history of dysuria, hematuria and restlessness. The goat was intensively managed (confined to the pen) and fed with only palm kernel cake for the last three months. Physical examination revealed that the goat was dull, depressed, having an inflamed penis and prepuce with blood stained urine dripping from the penis. The differential diagnoses were obstructive urolithiasis, urinary tract infection and balanoposthitis...
2015: Open veterinary journal
Carolina Guadalupe Sosa-Gutierrez, Maria Teresa Quintero Martinez, Soila Maribel Gaxiola Camacho, Silvia Cota Guajardo, Maria D Esteve-Gassent, María-Guadalupe Gordillo-Pérez
Ehrlichia canis is a rickettsial intracellular obligate bacterial pathogen and agent of canine monocytic ehrlichiosis. The prevalence of this disease in veterinary medicine can vary depending on the diagnostic method used and the geographic location. One hundred and fifty-two canine blood samples from six veterinary clinics and two shelters from Sinaloa State (Mexico) were analyzed in this study. All animals were suspected of having Canine Monocytic Ehrlichiosis (CME). The diagnostic methods used were the ELISA (Snap4Dx, IDEXX) together with blood smear and platelet count...
2013: Journal of veterinary medicine
RoseAnn Miller, Brian E Mavis, James W Lloyd, Chandra M Grabill, Rebecca C Henry, Coretta C Patterson
Veterinary medical school challenges students academically and personally, and some students report depression and anxiety at rates higher than the general population and other medical students. This study describes changes in veterinary medical student self-esteem (SE) over four years of professional education, attending to differences between high and low SE students and the characteristics specific to low SE veterinary medical students. The study population was students enrolled at the Michigan State University College of Veterinary Medicine from 2006 to 2012...
2015: Journal of Veterinary Medical Education
Randall J Nett, Tracy K Witte, Stacy M Holzbauer, Brigid L Elchos, Enzo R Campagnolo, Karl J Musgrave, Kris K Carter, Katie M Kurkjian, Cole F Vanicek, Daniel R O'Leary, Kerry R Pride, Renee H Funk
OBJECTIVE: To evaluate the prevalence of suicide risk factors, attitudes toward mental illness, and practice-related stressors among US veterinarians. DESIGN: Cross-sectional survey. SAMPLE: 11,627 US veterinarians. PROCEDURES: Between July 1 and October 20, 2014, a Web-based questionnaire was made available through the Veterinary Information Network (VIN), VIN News Service, JAVMA News, and email messages to US veterinarians sent by a veterinary medical association, agriculture or livestock department, or health department of each state (except Maine) and Puerto Rico...
October 15, 2015: Journal of the American Veterinary Medical Association
Angie Magaña, Félix Sánchez, Karina Villa, Liliana Rivera, Elizabeth Morales
A 4-year-old male Toy Poodle was presented to the Small Animal Veterinary Hospital of the Faculty of Veterinary Medicine of the Autonomous University of Mexico (FMVZ, UNAM) because of depression, lethargy, and hemorrhages involving several areas of the skin and around the eyes. Hematology data and a bone marrow analysis suggested hemolytic anemia and immune-mediated thrombocytopenia. The dog was treated with prednisone, and after one month the hematology variables improved. However, the dog's clinical condition inexplicably worsened and it was euthanized...
December 2015: Veterinary Clinical Pathology
Carla Miranda, Júlio Carvalheira, Colin R Parrish, Gertrude Thompson
Canine parvovirus (CPV) is the most important enteric virus infecting canids worldwide. The purpose of this study was to detect CPV in naturally infected dogs from several veterinary clinics distributed throughout Portugal between 2012 and 2014 and to identify risk factors associated with CPV infection. From 209 dogs suspected of being infected with CPV, historical data and clinical signs were collected. Fecal samples were screened for CPV by PCR assay and those positive were confirmed by sequencing. The data was analyzed using logistic regression to investigate associations between each of the predisposing factors and CPV status...
October 22, 2015: Veterinary Microbiology
Sarah Hangartner, Jasmin Steiner, Franz Dussy, Regula Moeckli, Kathrin Gerlach, Thomas Briellmann
We present an unusual case of suicide by intraperitoneal injection of pentobarbital, an overdose of zolpidem and the intake of diazepam, ethanol and other psychoactive substances. The autopsy and specimen collection were conducted in a 10 to 18 h postmortem interval. The toxicological analysis revealed a significantly higher pentobarbital concentration in femoral blood compared to cardiac blood (36 vs. 15 mg/L). On the contrary, zolpidem and diazepam concentrations in cardiac blood (2700 and 590 µg/L) were found to be significantly higher than in femoral blood (1500 and 230 µg/L)...
September 2016: International Journal of Legal Medicine
Hong You, Geoffrey N Gobert, Pengfei Cai, Rong Mou, Sujeevi Nawaratna, Guofu Fang, Francois Villinger, Donald P McManus
To further investigate the importance of insulin signaling in the growth, development, sexual maturation and egg production of adult schistosomes, we have focused attention on the insulin receptors (SjIRs) of Schistosoma japonicum, which we have previously cloned and partially characterised. We now show, by Biolayer Interferometry, that human insulin can bind the L1 subdomain (insulin binding domain) of recombinant (r)SjIR1 and rSjIR2 (designated SjLD1 and SjLD2) produced using the Drosophila S2 protein expression system...
May 2015: PLoS Neglected Tropical Diseases
A Eugene Pekary, Albert Sattin, Robert L Lloyd
Major depression is the largest single healthcare burden with treatments of slow onset and often limited efficacy. Ketamine, a NMDA antagonist used extensively as a pediatric and veterinary anesthetic, has recently been shown to be a rapid acting antidepressant, making it a potential lifesaver for suicidal patients. Side effects and risk of abuse limit the chronic use of ketamine. More complete understanding of the neurobiochemical mechanisms of ketamine should lead to safer alternatives. Some of the physiological and pharmacological actions of ketamine are consistent with increased synthesis and release of TRH (pGlu-His-Pro-NH2), and TRH-like peptides (pGlu-X-Pro-NH2) where "X" can be any amino acid residue...
July 2015: Peptides
(no author information available yet)
No abstract text is available yet for this article.
March 28, 2015: Veterinary Record
Kumiko Yonezaki, Kazuhiro Uchimoto, Tomoyuki Miyazaki, Ayako Asakura, Ayako Kobayashi, Kenkichi Takase, Takahisa Goto
Isoflurane was previously the major clinical anesthetic agent but is now mainly used for veterinary anesthesia. Studies have reported widespread sites of action of isoflurane, suggesting a wide array of side effects besides sedation. In the present study, we phenotyped isoflurane-treated mice to investigate the postanesthetic behavioral effects of isoflurane. We applied comprehensive behavioral test batteries comprising sensory test battery, motor test battery, anxiety test battery, depression test battery, sociability test battery, attention test battery, and learning test battery, which were started 7 days after anesthesia with 1...
2015: PloS One
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