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https://www.readbyqxmd.com/read/28090418/the-forgotten-lumbocostal-ligament-anatomical-study-with-application-to-thoracolumbar-surgery
#1
Erfanul Saker, Gabrielle G Tardieu, Fernando Alonso, Beom Sun Chung, Christian Fisahn, Marios Loukas, Rod J Oskouian, R Shane Tubbs
INTRODUCTION: Most ligaments of the human body have been well studied. However, the lumbocostal ligament has received little attention in the extant medical literature and, to our knowledge, has not undergone anatomical study. Therefore, the present study was performed to better characterize this structure's anatomy and relationships. METHODS: In the prone position, 10 adult cadavers underwent dissection of their lumbocostal ligaments. All specimens were unembalmed and had no history of surgery to the spine...
December 11, 2016: Curēus
https://www.readbyqxmd.com/read/28087837/off-target-effects-of-neuroleptics-and-antidepressants-on-saccharomyces-cerevisiae
#2
M Caldara, S Graziano, M Gullì, S Cadonici, Nelson Marmiroli
Over the past years, the use of antidepressants and neuroleptics has steadily increased. Although incredibly useful to treat disorders like depression, schizophrenia, epilepsy, or mental retardation, these drugs display many side effects. Toxicogenomic studies aim to limit this problem by trying to identify cellular targets and off-targets of medical compounds. The baker yeast Saccharomyces cerevisiae has been shown to be a key player in this approach, as it represents an incredible toolbox for the dissection of complex biological processes...
January 13, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/28080975/neural-correlates-of-heart-focused-interoception-a-functional-magnetic-resonance-imaging-meta-analysis
#3
REVIEW
Stefan M Schulz
Interoception is the ability to perceive one's internal body state including visceral sensations. Heart-focused interoception has received particular attention, in part due to a readily available task for behavioural assessment, but also due to accumulating evidence for a significant role in emotional experience, decision-making and clinical disorders such as anxiety and depression. Improved understanding of the underlying neural correlates is important to promote development of anatomical-functional models and suitable intervention strategies...
November 19, 2016: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28078566/an-eye-tracking-controlled-neuropsychological-battery-for-cognitive-assessment-in-neurological-diseases
#4
Barbara Poletti, Laura Carelli, Federica Solca, Annalisa Lafronza, Elisa Pedroli, Andrea Faini, Stefano Zago, Nicola Ticozzi, Andrea Ciammola, Claudia Morelli, Paolo Meriggi, Pietro Cipresso, Dorothée Lulé, Albert C Ludolph, Giuseppe Riva, Vincenzo Silani
Traditional cognitive assessment in neurological conditions involving physical disability is often prevented by the presence of verbal-motor impairment; to date, an extensive motor-verbal-free neuropsychological battery is not available for such purposes. We adapted a set of neuropsychological tests, assessing language, attentional abilities, executive functions and social cognition, for eye-tracking (ET) control, and explored its feasibility in a sample of healthy participants. Thirty healthy subjects performed a neuropsychological assessment, using an ET-based neuropsychological battery, together with standard "paper and pencil" cognitive measures for frontal (Frontal Assessment Battery-FAB) and working memory abilities (Digit Sequencing Task) and for global cognitive efficiency (Montreal Cognitive Assessment-MoCA)...
January 11, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28077190/measures-of-the-dsm-5-mixed-features-specifier-of-major-depressive-disorder
#5
Mark Zimmerman
During the past two decades, a number of studies have found that depressed patients frequently have manic symptoms intermixed with depressive symptoms. While the frequency of mixed syndromes are more common in bipolar than in unipolar depressives, mixed states are also common in patients with major depressive disorder. The admixture of symptoms may be evident when depressed patients present for treatment, or they may emerge during ongoing treatment. In some patients, treatment with antidepressant medication might precipitate the emergence of mixed states...
January 12, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28076649/suicide-attempts-in-bipolar-i-patients-impact-of-comorbid-personality-disorders
#6
Severino Bezerra, Amanda Galvão-de-Almeida, Paula Studart, Davi F Martins, André C Caribé, Paulo A Schwingel, Ângela Miranda-Scippa
Objective: To evaluate the association between personality disorders (PDs) and suicide attempts (SAs) in euthymic patients with type I bipolar disorder (BD). Methods: One-hundred twenty patients with type I BD, with and without history of SA, were evaluated during euthymia. The assessment included a clinical and sociodemographic questionnaire, the Hamilton Depression Rating Scale, the Young Mania Rating Scale, the Barratt Impulsiveness Scale, and Structured Clinical Interviews for DSM-IV Axis I and II Disorders...
January 9, 2017: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/28073061/the-significance-of-micrornas-in-the-course-of-rdd
#7
Kinga Bobińska, Janusz Szemraj, Joanna Mossakowska-Wójcik, Piotr Gałecki, Monika Talarowska
BACKGROUND: In recent years, special attention in genetic studies dedicated to the development of various diseases, including mental disorders, has been paid to micro ribonucleic acids (miRNA, microRNA). As an object of our analysis we have selected the miRNAs which - due to the profile of their activity - may be significant in the aetiology and course of recurrent depressive disorders, i.e. miRNA-370, miRNA-411, miRNA-433, miRNA-487b and miRNA-539. METHODS: The examined population included 138 patients suffering from depression and 95 individuals from the control group (CG)...
October 14, 2016: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28072836/pre-migration-trauma-exposure-and-mental-health-functioning-among-central-american-migrants-arriving-at-the-us-border
#8
Allen Keller, Amy Joscelyne, Megan Granski, Barry Rosenfeld
In recent years, increasing numbers of families and individuals have arrived at the U.S. border from Central America, in particular, from Honduras, El Salvador, and Guatemala. This study sought to examine pre-migration trauma exposure and current mental health functioning of migrant families arriving at the U.S. border from the Northern Triangle region, with specific attention to the reasons offered for leaving their home country and the frequency with which migrant families appear to satisfy legal criteria for asylum We interviewed 234 adults in McAllen, Texas, using a structured interview and standardized questionnaires to assess exposure to trauma prior to migration, reasons for leaving their home country and symptoms of posttraumatic stress and depression...
2017: PloS One
https://www.readbyqxmd.com/read/28072503/posttraumatic-stress-disorder-symptoms-and-cognitive-function-in-a-large-cohort-of-middle-aged-women
#9
Jennifer A Sumner, Kaitlin Hagan, Fran Grodstein, Andrea L Roberts, Brian Harel, Karestan C Koenen
BACKGROUND: Posttraumatic stress disorder (PTSD) has been linked to cognitive decline, but research in women is generally lacking. We examined whether trauma and elevated PTSD symptoms were associated with worse cognitive function in middle-aged civilian women. A secondary objective was to investigate the possible role of depression in the relation of PTSD symptoms to cognitive function. METHODS: The sample comprised 14,029 middle-aged women in the Nurses' Health Study II...
January 10, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28071929/effects-of-smartphone-based-memory-training-for-older-adults-with-subjective-memory-complaints-a-randomized-controlled-trial
#10
Seo Jin Oh, Sungmin Seo, Ji Hyun Lee, Myeong Ju Song, Min-Sup Shin
OBJECTIVES: We explored whether newly developed application (Smartphone-based brain Anti-aging and memory Reinforcement Training, SMART) improved memory performance in older adults with subjective memory complaints (SMC). METHOD: A total of 53 adults (range: 50-68 years; 52.8% female) were randomized into either one of two intervention groups [SMART (n = 18) vs. Fit Brains® (n = 19)] or a wait-list group (n = 16). Participants in the intervention groups underwent 15-20 minutes of training per day, five days per week for 8 weeks...
January 10, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28070409/the-mediating-role-of-social-support-in-the-relationship-between-psychological-well-being-and-health-risk-behaviors-among-chinese-university-students
#11
Catie Cw Lai, Cecilia Ms Ma
While literature has displayed a link between psychological well-being (i.e. depression, hopelessness, and life satisfaction) and health-risk behaviors (i.e. smoking, drinking, suicide, and physical inactivity), the mechanisms underlying this relationship have received little empirical attention. This study examines the mediation effects of social support (from family, friends, and significant others) that accounted for the link. Participants were 2023 university students (47.7% male). Structural equation modeling showed partial mediation effect of social support between psychological well-being and health-risk behaviors...
July 2016: Health Psychology Open
https://www.readbyqxmd.com/read/28070274/cunningham-s-skinks-show-low-genetic-connectivity-and-signatures-of-divergent-selection-across-its-distribution
#12
Benjamin Y Ofori, Linda J Beaumont, Adam J Stow
Establishing corridors of connecting habitat has become a mainstay conservation strategy to maintain gene flow and facilitate climate-driven range shifts. Yet, little attention has been given to ascertaining the extent to which corridors will benefit philopatric species, which might exhibit localized adaptation. Measures of genetic connectivity and adaptive genetic variation across species' ranges can help fill this knowledge gap. Here, we characterized the spatial genetic structure of Cunningham's skink (Egernia cunninghami), a philopatric species distributed along Australia's Great Dividing Range, and assessed evidence of localized adaptation...
January 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28068942/prevalence-of-burnout-depression-anxiety-and-stress-in-australian-midwives-a-cross-sectional-survey
#13
D K Creedy, M Sidebotham, J Gamble, Julie Pallant, J Fenwick
BACKGROUND: The health and wellbeing of midwives are important considerations for workforce retention and quality care. The occurrence and relationships among mental health conditions such as burnout and depression have received little attention. We investigated the prevalence of burnout, depression, anxiety and stress in Australian midwives. METHODS: An online survey was conducted in September 2014. Participants were recruited through the Australian College of Midwives and professional networks...
January 9, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28067423/current-standards-of-neuropsychological-assessment-in-epilepsy-surgery-centers-across-europe
#14
Viola Lara Vogt, Marja Äikiä, Antonio Del Barrio, Paul Boon, Csaba Borbély, Ema Bran, Kees Braun, Evelien Carette, Maria Clark, Judith Helen Cross, Petia Dimova, Daniel Fabo, Nikolaos Foroglou, Stefano Francione, Anna Gersamia, Antonio Gil-Nagel, Alla Guekht, Sue Harrison, Hrvoje Hecimovic, Einar Heminghyt, Edouard Hirsch, Alena Javurkova, Reetta Kälviäinen, Nicole Kavan, Anna Kelemen, Vasilios K Kimiskidis, Margarita Kirschner, Catherine Kleitz, Teia Kobulashvili, Mary H Kosmidis, Selin Yagci Kurtish, Mathieu Lesourd, Sofia Ljunggren, Morten Ingvar Lossius, Kristina Malmgren, Ruta Mameniskiené, Patricia Martin-Sanfilippo, Petr Marusic, Marijke Miatton, Çiğdem Özkara, Federica Pelle, Guido Rubboli, Sarah Rudebeck, Philippe Ryvlin, Monique van Schooneveld, Elisabeth Schmid, Pia-Magdalena Schmidt, Margitta Seeck, Bernhard J Steinhoff, Sara Shavel-Jessop, Oana Tarta-Arsene, Eugen Trinka, Gerd Viggedal, Anne-Sophie Wendling, Juri-Alexander Witt, Christoph Helmstaedter
We explored the current practice with respect to the neuropsychological assessment of surgical epilepsy patients in European epilepsy centers, with the aim of harmonizing and establishing common standards. Twenty-six epilepsy centers and members of "E-PILEPSY" (a European pilot network of reference centers in refractory epilepsy and epilepsy surgery), were asked to report the status of neuropsychological assessment in adults and children via two different surveys. There was a consensus among these centers regarding the role of neuropsychology in the presurgical workup...
January 9, 2017: Epilepsia
https://www.readbyqxmd.com/read/28064416/association-of-mood-disorders-with-serum-zinc-concentrations-in-adolescent-female-students
#15
Kobra Tahmasebi, Reza Amani, Zahra Nazari, Kambiz Ahmadi, Sara Moazzen, Seyed-Ali Mostafavi
Among various factors influencing mood disorders, the impact of micronutrient deficiencies has attracted a great attention. Zinc deficiency is considered to play a crucial role in the onset and progression of mood disorders in different stages of life. The main objective of this study was to assess the correlation between serum zinc levels and mood disorders in high school female students. This cross-sectional study was conducted on a random sample of 100 representative high school female students. The participants completed 24-h food recall questionnaires to assess the daily zinc intakes...
January 7, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28064114/extreme-sensory-processing-patterns-show-a-complex-association-with-depression-and-impulsivity-alexithymia-and-hopelessness
#16
Gianluca Serafini, Xenia Gonda, Giovanna Canepa, Maurizio Pompili, Zoltan Rihmer, Mario Amore, Batya Engel-Yeger
INTRODUCTION: The involvement of extreme sensory processing patterns, impulsivity, alexithymia, and hopelessness was hypothesized to contribute to the complex pathophysiology of major depression and bipolar disorder. However, the nature of the relation between these variables has not been thoroughly investigated. AIMS: This study aimed to explore the association between extreme sensory processing patterns, impulsivity, alexithymia, depression, and hopelessness. METHODS: We recruited 281 euthymic participants (mean age=47...
December 22, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28064113/cognitive-control-dysfunction-in-emotion-dysregulation-and-psychopathology-of-major-depression-md-evidence-from-transcranial-brain-stimulation-of-the-dorsolateral-prefrontal-cortex-dlpfc
#17
Mohammad Ali Salehinejad, Elham Ghanavai, Reza Rostami, Vahid Nejati
BACKGROUND: Previous studies showed that MD is associated with a variety of cognitive deficits and executive dysfunctions which can persist even in remitted states. However, the role of cognitive impairments in MD psychopathology and treatment is not fully understood. This article aims to discuss how executive functions central components (e.g., Working memory and attention) mediate MD psychopathology considering the role of dorsolateral prefrontal cortex (dLPFC) and present findings of a brain stimulation experiment to support this notion...
December 31, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28064112/ultra-short-screening-instruments-for-major-depressive-episode-and-generalized-anxiety-disorder-in-epilepsy-the-nddie-2-and-the-gad-si
#18
Jean-Arthur Micoulaud-Franchi, Fabrice Bartolomei, Aileen McGonigal
BACKGROUND: Systematic screening is recommended for major depressive episode (MDE) with the Neurological Disorders Depression Inventory for Epilepsy NDDI-E, 6 items and generalized anxiety disorder (GAD) with the GAD 7 items in patients with epilepsy (PWE). Shorter versions of the NDDI-E and the GAD-7 could facilitate increased screening by busy clinicians and be more accessible to patients with mild cognitive and/or language impairments. METHODS: The effectiveness of ultra-short versions of the NDDI-E (2 items) and the GAD-7 (the GAD-2, 2 items, and the GAD-SI with a single item) in comparison with the original versions were statistically tested using ROC analysis...
December 27, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28064028/resilient-empowered-active-living-with-diabetes-real-diabetes-study-methodology-and-baseline-characteristics-of-a-randomized-controlled-trial-evaluating-an-occupation-based-diabetes-management-intervention-for-young-adults
#19
Elizabeth A Pyatak, Kristine Carandang, Cheryl Vigen, Jeanine Blanchard, Paola A Sequeira, Jamie R Wood, Donna Spruijt-Metz, Robin Whittemore, Anne L Peters
OVERVIEW: This paper describes the study protocol used to evaluate the Resilient, Empowered, Active Living with Diabetes (REAL Diabetes) intervention and reports on baseline characteristics of recruited participants. REAL Diabetes is an activity-based intervention designed to address the needs of young adults diagnosed with type 1 (T1D) or type 2 diabetes (T2D) from low socioeconomic status or racial/ethnic minority backgrounds. The REAL intervention incorporates tailored delivery of seven content modules addressing various dimensions of health and well-being as they relate to diabetes, delivered by a licensed occupational therapist...
January 5, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28063400/relationships-between-neuropsychological-variables-and-factor-analysed-symptom-dimensions-in-obsessive-compulsive-disorder
#20
Himani Kashyap, J Keshav Kumar, Thennarasu Kandavel, Y C Janardhan Reddy
Despite mounting evidence for the distinctiveness of symptom dimensions in obsessive-compulsive disorder, neuropsychological studies have been few, focused on small samples, and relying on classification of participants based on mutually exclusive symptom categories, resulting in lack of concordance across neuropsychological and imaging studies. Neuropsychological assessment was undertaken with 150 individuals with DSM IV OCD, and neuropsychological variables were analysed in relation to symptom dimension scores derived from factor analysis...
December 29, 2016: Psychiatry Research
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