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https://www.readbyqxmd.com/read/29656269/task-positive-and-task-negative-networks-in-major-depressive-disorder-a-combined-fmri-and-eeg-study
#1
Gennady G Knyazev, Alexander N Savostyanov, Andrey V Bocharov, Ivan V Brak, Evgeny A Osipov, Elena A Filimonova, Alexander E Saprigyn, Lyubomir I Aftanas
BACKGROUND: The study of intrinsic connectivity networks, i.e., sets of brain regions that show a high degree of interconnectedness even in the absence of a task, showed that major depressive disorder (MDD) patients demonstrate an increased connectivity within the default mode network (DMN), which is active in a resting state and is implicated in self-referential processing, and a decreased connectivity in task-positive networks (TPNs), which increase their activity in attention tasks...
April 7, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29656030/post-stroke-depression-the-sequelae-of-cerebral-stroke
#2
REVIEW
Jyotirekha Das, G K Rajanikant
Post-stroke depression (PSD) is the most common mental health issue, afflicting around 33% of stroke survivors. PSD has a negative impact on the rehabilitation, recuperation of motor and cognitive deficits following stroke and significantly increases the chances of relapsing neurovascular events. It has been demonstrated that biological and psychological factors have a significant role in PSD. Numerous endeavors have been made to discover the risk factors and predictors of PSD. Screening and diagnosis also have gained attention; however, a suitable tool is yet to be developed...
April 12, 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29653375/feeling-fat-in-eating-disorders-testing-the-unique-relationships-between-feeling-fat-and-measures-of-disordered-eating-in-anorexia-nervosa-and-bulimia-nervosa
#3
Jake Linardon, Andrea Phillipou, David Castle, Richard Newton, Philippa Harrison, Leonardo L Cistullo, Scott Griffiths, Annemarie Hindle, Leah Brennan
Although widely discussed in theories of eating disorders, the experience of "feeling fat" in this population has received little research attention. This study tested the unique relationships between feeling fat and measures of problematic eating behaviours and attitudes. Data were analysed from individuals with anorexia nervosa (AN; n = 123) and bulimia nervosa (BN; n = 51). Correlations revealed considerable unshared variance between feeling fat and shape and weight over-evaluation and depressive symptoms...
April 10, 2018: Body Image
https://www.readbyqxmd.com/read/29653295/feasibility-of-a-mindfulness-based-cognitive-therapy-group-intervention-as-an-adjunctive-treatment-for-postpartum-depression-and-anxiety
#4
Barbara Shulman, Royce Dueck, Deirdre Ryan, Genevieve Breau, Isabel Sadowski, Shaila Misri
BACKGROUND: Many women experience moderate-to-severe depression and anxiety in the postpartum period for which pharmacotherapy is often the first-line treatment. Many breastfeeding mothers are reticent to increase their dose or consider additional medication, despite incomplete response, due to potential adverse effects on their newborn. These mothers are amenable to non-pharmacological intervention for complete symptom remission. The current study evaluated the feasibility of an eight-week mindfulness-based cognitive therapy (MBCT) intervention as an adjunctive treatment for postpartum depression and anxiety...
January 2, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29652529/neurocognitive-predictors-of-clinical-improvement-in-selective-serotonin-reuptake-inhibitor-treated-adolescents-with-major-depressive-disorder
#5
Fadi Maalouf, Rinad Bakhti, Hani Tamim, Safa Shehab, David Brent
OBJECTIVES: Numerous studies have suggested cognitive deficits as consistently associated with adolescent depression. No study to date, however, has assessed neurocognitive predictors of selective serotonin reuptake inhibitor (SSRI) treatment response in adolescents with depression. This study examined neurocognitive tasks at baseline as predictors of clinical improvement with SSRI treatment (fluoxetine) at week 6 and 12 in an adolescent population. METHODS: Adolescents with depression were recruited from a child and adolescent psychiatry outpatient clinic at a university medical center...
April 13, 2018: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29651972/n-3-omega-3-fatty-acids-effects-on-brain-dopamine-systems-and-potential-role-in-the-etiology-and-treatment-of-neuropsychiatric-disorders
#6
Beth Levant, Michelle Healy-Stoffel
A number of neuropsychiatric disorders, including Parkinson's disease, schizophrenia, attention deficit hyperactivity disorder, and, to some extent, depression, involve dysregulation of the brain dopamine systems. The etiology of these diseases is multifactorial, involving genetic and environmental factors. Evidence suggests that inadequate levels of n-3 (omega-3) polyunsaturated fatty acids (PUFA) in the brain may represent a risk factor for these disorders. These fatty acids, which are derived from the diet, are a major component of neuronal membranes and are of particular importance in brain development and function...
April 12, 2018: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/29651672/factors-associated-with-anxiety-and-depression-in-cancer-patients-prior-to-initiating-adjuvant-therapy
#7
P Jimenez-Fonseca, C Calderón, R Hernández, T Ramón Y Cajal, M Mut, A Ramchandani, O Donnay, A Carmona-Bayonas
OBJECTIVE: Anxiety and depression affect cancer patients' quality of life. Our objectives were to determine the prevalence of anxiety and depression and analyze the association between positive psychological factors, sociodemographic factors, and clinical factors in oncological patients initiating adjuvant treatment. METHODS: A prospective, multicenter cohort of 600 consecutive patients completed the Brief Symptom Inventory, Mini-Mental Adjustment to Cancer, Life Orientation Scale-Revised, and Multidimensional Scale of Perceived Social Support questionnaires...
April 12, 2018: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/29651505/the-role-of-psychiatric-status-on-pediatric-extremity-fractures-a-prospective-analysis
#8
Altuğ Duramaz, Semra Yilmaz, Nezih Ziroğlu, Burcu Bursal Duramaz, Berhan Bayram, Tayfun Kara
PURPOSE: The aim of the study was to investigate the relationship between attention deficit and hyperactivity disorder (ADHD), anxiety, and depression with pediatric extremity fractures. METHODS: Between November 2014 and November 2016, consecutive 138 patients with pediatric extremity fractures were prospectively investigated in terms of the tendency to anxiety, depression, or ADHD in the study group. Consecutive 168 non-trauma patients who were admitted to general pediatrics outpatient clinic were included the control group...
April 12, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29649684/the-rome-retrospective-observational-multicenter-study-on-eslicarbazepine-study-efficacy-and-behavioural-effects-of-eslicarbazepine-acetate-as-adjunctive-therapy-for-adults-with-partial-onset-seizures-in-real-life
#9
G Assenza, O Mecarelli, J Lanzone, F Assenza, M Tombini, V Di Lazzaro, P Pulitano
PURPOSE: Eslicarbazepine acetate (ESL) is a third-generation member of the dibenzazepine family approved in 2009 by the European Medicines Agency with the indication of adjunctive therapy in adult people with partial-onset seizures (PPOS). We aimed at assessing the ESL impact on seizure frequency and quality of life in PPOS with a particular attention to sleepiness and depression. METHODS: We evaluated 50 adult PPOS (>18 years; 48 ± 14 years-old; 23 males) treated with adjunctive ESL for ≥2months with a retrospective multi-centric design...
March 30, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29649022/effectiveness-of-chinese-martial-arts-and-philosophy-to-reduce-reactive-and-proactive-aggression-in-schoolchildren
#10
Annis Lai Chu Fung, Toney Ka Hung Lee
OBJECTIVE: This study examined the effectiveness of Chinese martial arts in reducing reactive and proactive aggressive behavior among schoolchildren with a cluster-randomized trial. METHODS: A screening questionnaire was completed by 3511 schoolchildren of Grades 2 to 5 from 13 sites in Hong Kong. We shortlisted 298 children who scored z ≥ 1 on the total score of the Reactive-Proactive Aggression Questionnaire in their respective sites to participate in the experiment...
April 10, 2018: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29648989/analysis-of-sexual-problems-in-men-with-psoriasis
#11
Marta Wojciechowska-Zdrojowy, Adam Reich, Jacek C Szepietowski, Adam Wojciechowski
INTRODUCTION: Psoriasis may have negative impact on many aspects of patient life. OBJECTIVE: The aim of the study was to evaluate the influence of psoriasis on erectile dysfunction and other sexual problems in men with psoriasis. MATERIALS AND METHODS: A total of 76 men aged between 20 and 66 years (mean 43.9±13.2 years) were enrolled. Psoriasis severity assessed according to PASI ranged from 2.0 to 49.8 points (mean 15.1±10.3 points). All patients were asked to complete International Index of Erectile Function (IIEF-5), Beck's Depression Inventory and Dermatology Life Quality Index...
April 12, 2018: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/29648599/polycystic-ovary-syndrome-is-associated-with-adverse-mental-health-and-neurodevelopmental-outcomes
#12
Thomas R Berni, Christopher L Morgan, Ellen R Berni, D Aled Rees
Context: Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism and subfertility but the effects on mental health and child neurodevelopment are unclear. Objectives: To determine if (i) there is an association between PCOS and psychiatric outcomes, and (ii) whether rates of autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) are higher in children of mothers with PCOS. Design: Data were extracted from the Clinical Practice Research Datalink...
April 10, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29644474/risk-factors-for-parental-psychopathology-a-study-in-families-with-children-or-adolescents-with-psychopathology
#13
L W Wesseldijk, G C Dieleman, F J A van Steensel, M Bartels, J J Hudziak, R J L Lindauer, S M Bögels, C M Middeldorp
The parents of children with psychopathology are at increased risk for psychiatric symptoms. To investigate which parents are mostly at risk, we assessed in a clinical sample of families with children with psychopathology, whether parental symptom scores can be predicted by offspring psychiatric diagnoses and other child, parent and family characteristics. Parental depressive, anxiety, avoidant personality, attention-deficit/hyperactivity (ADHD), and antisocial personality symptoms were measured with the Adult Self Report in 1805 mothers and 1361 fathers of 1866 children with a psychiatric diagnosis as assessed in a child and adolescent psychiatric outpatient clinic...
April 11, 2018: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29643977/role-and-possible-mechanisms-of-sirt1-in-depression
#14
REVIEW
Guofang Lu, Jianguo Li, Hongmei Zhang, Xin Zhao, Liang-Jun Yan, Xiaorong Yang
Depression is a common, devastating illness. Due to complicated causes and limited treatments, depression is still a major problem that plagues the world. Silent information regulator 1 (Sirt1) is a deacetylase at the consumption of NAD+ and is involved in gene silencing, cell cycle, fat and glucose metabolism, cellular oxidative stress, and senescence. Sirt1 has now become a critical therapeutic target for a number of diseases. Recently, a genetic study has received considerable attention for depression and found that Sirt1 is a potential gene target...
2018: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29642887/association-between-level-of-suicide-risk-characteristics-of-suicide-attempts-and-mental-disorders-among-suicide-attempters
#15
Subin Park, Yeeun Lee, Tak Youn, Byung Soo Kim, Jong Ik Park, Haesoo Kim, Hyo Chu Lee, Jin Pyo Hong
BACKGROUND: Past attempted suicide is a strong predictor of future suicide risk, but the risk varies among suicide attempters. Hence, it is important to clarify distinguishing features of lifetime attempters with a high level of current suicide risk for efficient preventive management. METHODS: We compared characteristics of suicide attempts and clinical characteristics among high-, moderate-, and low-risk attempters. Among the total of 6022 participants in the Korean Epidemiologic Catchment Area study, 193 reported a suicide attempt in their lifetime, 36 of which had high, 126 moderate, and 30 low levels of current suicide risk (1 incomplete response)...
April 11, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29629247/effects-of-mental-health-interventions-for-students-in-higher-education-are-sustainable-over-time-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#16
Regina Winzer, Lene Lindberg, Karin Guldbrandsson, Anna Sidorchuk
Background: Symptoms of depression, anxiety, and distress are more common in undergraduates compared to age-matched peers. Mental ill health among students is associated with impaired academic achievement, worse occupational preparedness, and lower future occupational performance. Research on mental health promoting and mental ill health preventing interventions has shown promising short-term effects, though the sustainability of intervention benefits deserve closer attention. We aimed to identify, appraise and summarize existing data from randomized control trials (RCTs) reporting on whether the effects of mental health promoting and mental ill health preventing interventions were sustained at least three months post-intervention, and to analyze how the effects vary for different outcomes in relation to follow-up length...
2018: PeerJ
https://www.readbyqxmd.com/read/29628881/posture-motor-and-posture-ideomotor-dual-tasking-a-putative-marker-of-psychomotor-retardation-and-depressive-rumination-in-patients-with-major-depressive-disorder
#17
Lyubomir I Aftanas, Olga M Bazanova, Nataliya V Novozhilova
Background: Recent studies have demonstrated that the assessment of postural performance may be a potentially reliable and objective marker of the psychomotor retardation (PMR) in the major depressive disorder (MDD). One of the important facets of MDD-related PMR is reflected in disrupted central mechanisms of psychomotor control, heavily influenced by compelling maladaptive depressive rumination. In view of this we designed a research paradigm that included sequential execution of simple single-posture task followed by more challenging divided attention posture tasks, involving concurring motor and ideomotor workloads...
2018: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29628188/dynamic-erbb4-activity-in-hippocampal-prefrontal-synchrony-and-top-down-attention-in-rodents
#18
Zhibing Tan, Heath L Robinson, Dong-Min Yin, Yu Liu, Fang Liu, Hongsheng Wang, Thiri W Lin, Guanglin Xing, Lin Gan, Wen-Cheng Xiong, Lin Mei
Top-down attention is crucial for meaningful behaviors and impaired in various mental disorders. However, its underpinning regulatory mechanisms are poorly understood. We demonstrate that the hippocampal-prefrontal synchrony associates with levels of top-down attention. Both attention and synchrony are reduced in mutant mice of ErbB4, a receptor of neuregulin-1. We used chemical genetic and optogenetic approaches to inactivate ErbB4 kinase and ErbB4+ interneurons, respectively, both of which reduce gamma-aminobutyric acid (GABA) activity...
April 3, 2018: Neuron
https://www.readbyqxmd.com/read/29628038/-patterns-of-detection-of-mild-cognitive-impairment-in-nursing
#19
Ana J Sebastián Hernández, Luís Carlos Arranz Santamaría
Mild cognitive impairment (MCI) is characterized by an acquired cognitive loss that places individuals, mainly older adults, in an intermediate stage between normal cognitive functioning and dementia. This impairment has a high risk of progression to dementia and is suitable for screening, which allows more effective early intervention. Nursing professionals, especially community-based primary care nurses, play an important role in the detection and follow-up of MCI and in interventions for this condition. The first step should be to take a thorough history from both the patient and his or her carers, which should assess the changes occurring in the patient's daily, family and social life through functional patterns...
June 2017: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/29627947/incidence-and-risk-factors-for-mortality-following-bariatric-surgery-a-nationwide-registry-study
#20
Nasser Sakran, Shiri Sherf-Dagan, Orit Blumenfeld, Orly Romano-Zelekha, Asnat Raziel, Dean Keren, Itamar Raz, Dan Hershko, Ian M Gralnek, Tamy Shohat, David Goitein
BACKGROUND: Although bariatric surgery (BS) is considered safe, concern remains regarding severe post-operative adverse events and mortality. Using a national BS registry, the aim of this study was to assess the incidence, etiologies, and risk factors for mortality following BS. METHODS: Prospective data from the National Registry of Bariatric Surgery in Israel (NRBS) including age, gender, BMI, comorbidities, and surgical procedure information were collected for all patients who underwent BS in Israel between June 2013 and June 2016...
April 7, 2018: Obesity Surgery
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