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https://www.readbyqxmd.com/read/28727668/comprehensive-cardiac-rehabilitation-for-secondary-prevention-after-transient-ischemic-attack-or-mild-stroke-psychological-profile-and-outcomes
#1
Peter L Prior, Vladimir Hachinski, Richard Chan, Karen Unsworth, Sharon Mytka, Michael Harnadek, Christina OʼCallaghan, Neville Suskin
PURPOSE: Having previously reported that comprehensive cardiac rehabilitation (CCR) is effective for secondary prevention post-transient ischemic attack (TIA)/mild nondisabling stroke (MNDS), we present psychometric findings for the same sample that elucidate subacute TIA/MNDS psychological outcomes and test whether CCR would be independently associated with psychological improvements. METHODS: In this prospective cohort trial patients with ≥1 risk factor, recruited from a stroke prevention clinic within 12 months (mean = 11...
July 19, 2017: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/28727546/a-formative-evaluation-of-a-diabetes-prevention-program-using-the-re-aim-framework-in-a-learning-health-care-system-utah-2013-2015
#2
Kimberly D Brunisholz, Jaewhan Kim, Lucy A Savitz, Mia Hashibe, Lisa H Gren, Sharon Hamilton, Kelly Huynh, Elizabeth A Joy
INTRODUCTION: Evaluation of interventions can help to close the gap between research and practice but seldom takes place during implementation. Using the RE-AIM framework, we conducted a formative evaluation of the first year of the Intermountain Healthcare Diabetes Prevention Program (DPP). METHODS: Adult patients who met the criteria for prediabetes (HbA1c of 5.70%-6.49% or fasting plasma glucose of 100-125 mg/dL) were attributed to a primary care provider from August 1, 2013, through July 31, 2014...
July 20, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/28727514/similarity-in-romantic-couples-drinking-motivations-and-drinking-behaviours
#3
Ivy-Lee L Kehayes, Sean P Mackinnon, Simon B Sherry, Kenneth E Leonard, Sherry H Stewart
BACKGROUND: Research suggests enhancement, conformity, social, coping-with-anxiety, and coping-with-depression drinking motives are linked to specific drinking outcomes in a theoretically-expected manner. Social learning theory suggests people who spend more time together emulate each other's behaviour to acquire reinforcing outcomes. The present study sought to integrate drinking motives theory and social learning theory to investigate similarity in drinking behaviours and drinking motives in romantic couples...
July 20, 2017: Substance Abuse
https://www.readbyqxmd.com/read/28726481/a-randomized-controlled-trial-of-an-online-modular-active-learning-training-program-for-behavioral-activation-for-depression
#4
Ajeng J Puspitasari, Jonathan W Kanter, Andrew M Busch, Rachel Leonard, Shira Dunsiger, Shawn Cahill, Christopher Martell, Kelly Koerner
OBJECTIVE: This randomized-controlled trial assessed the efficacy of a trainer-led, active-learning, modular, online behavioral activation (BA) training program compared with a self-paced online BA training with the same modular content. METHOD: Seventy-seven graduate students (M = 30.3 years, SD = 6.09; 76.6% female) in mental health training programs were randomly assigned to receive either the trainer-led or self-paced BA training. Both trainings consisted of 4 weekly sessions covering 4 core BA strategies...
August 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28720029/the-effects-of-the-relaxation-response-on-nurses-level-of-anxiety-depression-well-being-work-related-stress-and-confidence-to-teach-patients
#5
Catherine Calder Calisi
PURPOSE: The purpose of this pilot study was threefold: to teach nurses the Relaxation Response ( RR), a relaxation technique created by Benson; to measure the effects of the RR on nurses' levels of anxiety, depression, well-being, and work-related stress; and to explore nurses' confidence in teaching their patients the RR. DESIGN: A wait-list, randomized-control quantitative study design was used. METHOD: Nurses in the intervention group were trained on the benefits and the technique of the RR and were then asked to practice the RR over an 8-week period...
July 1, 2017: Journal of Holistic Nursing: Official Journal of the American Holistic Nurses' Association
https://www.readbyqxmd.com/read/28718181/erythropoietin-for-cognitive-deficits-associated-with-schizophrenia-bipolar-disorder-and-major-depression-a-systematic-review
#6
Xian-Bin Li, Wei Zheng, Yu-Ping Ning, Dong-Bin Cai, Xin-Hu Yang, Gabor S Ungvari, Chee H Ng, Chuan-Yue Wang, Yu-Tao Xiang
Introduction The purpose of this study is to systematically review the efficacy and safety of adjunctive erythropoietin (EPO) in treating cognitive deficits associated with schizophrenia, bipolar disorder, and major depression based on randomized controlled trials (RCTs). Methods Two evaluators independently and systematically searched and selected studies, extracted data, and conducted quality assessment. Results Four RCTs with 144 patients (71 in the EPO group and 73 in the placebo group) met the study entry criteria...
July 17, 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/28716769/web-based-therapist-training-in-interpersonal-psychotherapy-for-depression-pilot-study
#7
Kenneth A Kobak, Joshua D Lipsitz, John C Markowitz, Kathryn L Bleiberg
BACKGROUND: Training mental health professionals to deliver evidence-based therapy (EBT) is now required by most academic accreditation bodies, and evaluating the effectiveness of such training is imperative. However, shortages of time, money, and trained EBT clinician teachers make these challenges daunting. New technologies may help. The authors have developed the first empirically evaluated comprehensive Internet therapist training program for interpersonal psychotherapy (IPT). OBJECTIVE: The aim of this study was to examine whether (1) the training protocol would increase clinicians' knowledge of IPT concepts and skills and (2) clinicians would deem the training feasible as measured by satisfaction and utility ratings...
July 17, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28716162/changing-our-thinking-about-changing-their-thinking-in-older-adulthood
#8
Viviana M Wuthrich
It is well-established that as people age, deterioration in cognitive abilities including processing speed, memory, and cognitive flexibility occurs, although vast individual differences occur in the rate and consequences of this decline (Christensen, 2001). Anxiety and depression in late life are also associated with specific cognitive deficits in memory and executive functioning that may impact on new learning (Yochim et al., 2013). Therefore, it is possible that cognitive changes make it more difficult for older adults to learn how to change their thinking particularly in the context of psychological therapy...
July 18, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28716117/stress-prevention-work-a-study-protocol-for-the-evaluation-of-a-multifaceted-integral-stress-prevention-strategy-to-prevent-employee-stress-in-a-healthcare-organization-a-cluster-controlled-trial
#9
Rianne J A Hoek, Bo M Havermans, Irene L D Houtman, Evelien P M Brouwers, Yvonne F Heerkens, Moniek C Zijlstra-Vlasveld, Johannes R Anema, Allard J van der Beek, Cécile R L Boot
BACKGROUND: Adequate implementation of work-related stress management interventions can reduce or prevent work-related stress and sick leave in organizations. We developed a multifaceted integral stress-prevention strategy for organizations from several sectors that includes a digital platform and collaborative learning network. The digital platform contains a stepwise protocol to implement work-related stress-management interventions. It includes stress screeners, interventions and intervention providers to facilitate access to and the selection of matching work-related stress-management interventions...
July 17, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28715850/how-willing-are-you-willingness-as-a-predictor-of-change-during-treatment-of-adults-with-obsessive-compulsive-disorder
#10
Adam M Reid, Lauryn E Garner, Nathaniel Van Kirk, Christina Gironda, Jason W Krompinger, Brian P Brennan, Brittany M Mathes, Sadie Cole Monaghan, Eric D Tifft, Marie-Christine André, Jordan Cattie, Jesse M Crosby, Jason A Elias
OBJECTIVE: Exposure and response prevention (ERP) is an effective treatment for individuals with obsessive-compulsive disorder (OCD), yet a substantial number of individuals with OCD do not fully respond to this intervention. Based on emerging experimental and clinical research on acceptance, this study sought to explore whether willingness to experience unpleasant thoughts, emotions, and bodily sensations during ERP was associated with improved treatment response. METHODS: Two hundred eighty-eight adults with OCD receiving residential ERP provided self-rated willingness and other exposure-related variables during each daily coached ERP session...
July 17, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28715685/metabolic-profile-study-of-7-8-dihydroxyflavone-in-monkey-plasma-using-high-performance-liquid-chromatography-tandem-mass-spectrometry
#11
Taoping Sun, Sijing Chen, Hao Huang, Tianqing Li, Wei Yang, Liegang Liu
7, 8-Dihydroxyflavone, as a high-affinity tropomyosin-receptor-kinase B agonist, can mimic the physiological actions of brain-derived neurotrophic factor and exert a variety of neurological actions in numerous models including Parkinsońs disease, depression, learning and memory. Nonetheless, a limited number of studies have been focused on its metabolism in mammal and no methodology has been reported for the determination of 7, 8-DHF and its metabolites. Herein, we developed a rapid, sensitive and accurate method using high performance liquid chromatography-tandem mass spectroscopy for the determination of 7, 8-DHF and its metabolites in monkey plasma...
July 4, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28714604/antidepressants-antipsychotics-and-mood-stabilizers-in-pregnancy-what-do-we-know-and-how-should-we-treat-pregnant-women-with-depression
#12
REVIEW
Asher Ornoy, Liza Weinstein-Fudim, Zivanit Ergaz
Depression is generally treated with antidepressants, but may often need antipsychotics and mood stabilizers. We discuss the updated data regarding the safety in pregnancy of antidepressants and antipsychotics, except selective serotonin reuptake inhibitors, and their possible impact on the long-term development of the offspring. Several earlier studies demonstrated a slight increase in the rate of major anomalies following maternal tricyclic antidepressant treatment, but most current literature shows their relative safety in pregnancy...
July 17, 2017: Birth defects research
https://www.readbyqxmd.com/read/28714388/the-prospective-role-of-micrornas-in-depression
#13
Zhiying Hu, Yuting Jiang, Xue Huo, Yang Yang, Henry Davies, Benson O A Botchway, Marong Fang
Depression is a debilitating disease that is affecting a growing number of patients both physically and mentally. In addition to the mood changes, depression causes cognitive impairment, including learning and memory dysfunction. Although depression studies have been going on for decades, the underlying mechanism still remains unclear. MicroRNAs (miRNAs), a type of small non-coding RNAs, predominantly control the expression of their target mRNAs to exert their functions. Some evidence has revealed the importance of miRNAs in the mechanism of depression though the studies are still in their infancy...
July 14, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28713687/group-psychological-intervention-for-maternal-depression-a-nested-qualitative-study-from-karachi-pakistan
#14
Nusrat Husain, Nasim Chaudhry, Christine Furber, Hina Fayyaz, Tayyeba Kiran, Farah Lunat, Raza Ur Rahman, Saira Farhan, Batool Fatima
AIM: To understand the experience of maternal depression, the factors implicated in accessing health, and the acceptability of the psychosocial intervention. METHODS: The participants were recruited from the paediatrics outpatient department of Civil Hospital Karachi, Pakistan. The study started in December 2009 and completed in December 2010. Women with maternal depression, aged 18-44 years with children aged 0-30 mo who had received nutritional supplements, and participated in the intervention programme [called Learning through Play (LTP) plus] were included in the study...
June 22, 2017: World Journal of Psychiatry
https://www.readbyqxmd.com/read/28712841/long-term-impact-of-subthalamic-stimulation-on-cognitive-function-in-patients-with-advanced-parkinson-s-disease
#15
M Acera, A Molano, B Tijero, G Bilbao, I Lambarri, R Villoria, J Somme, E Ruiz de Gopegui, I Gabilondo, J C Gomez-Esteban
OBJECTIVE: The aim of this study was to evaluate the effects of deep brain stimulation of the subthalamic nucleus (DBS-SN) on cognitive function in patients with Parkinson's disease (PD) 5 years after surgery. MATERIAL AND METHODS: We conducted a prospective study including 50 patients with PD who underwent DBS-SN (62.5% were men; mean age of 62.2±8.2 years; mean progression time of 14.1±6.3 years). All patients were assessed before the procedure and at one year after surgery; 40 patients were further followed up until the 5-year mark...
July 13, 2017: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/28712815/asymptomatic-carotid-stenosis-is-associated-with-cognitive%C3%A2-impairment
#16
Brajesh K Lal, Moira C Dux, Siddhartha Sikdar, Carly Goldstein, Amir A Khan, John Yokemick, Limin Zhao
BACKGROUND: Cerebrovascular risk factors (eg, hypertension, coronary artery disease) and stroke can lead to vascular cognitive impairment. The Asymptomatic Carotid Stenosis and Cognitive Function study evaluated the isolated impact of asymptomatic carotid stenosis (no prior ipsilateral or contralateral stroke or transient ischemic attack) on cognitive function. Cerebrovascular hemodynamic and carotid plaque characteristics were analyzed to elucidate potential mechanisms affecting cognition...
July 13, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28710824/a-novel-study-on-association-between-untreated-hearing-loss-and-cognitive-functions-of-older-adults-baseline-non-verbal-cognitive-assessment-results
#17
Dona M P Jayakody, Peter L Friedland, Robert H Eielboom, Ralph N Martins, Hamid R Sohrabi
BACKGROUND: Age-related hearing loss (ARHL) is highly prevalent in older adults and more than two-thirds above age 70 years suffer from ARHL. Recent studies have established a link between ARHL and cognitive impairment, however, most of the studies have used verbally loaded cognitive measures to investigate the association between ARHL and cognition. It is possible that due to hearing impairment, the elderly may experience difficulty in following verbal instructions or completing tasks that heavily rely on hearing during cognitive assessments...
July 15, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28702811/a-machine-learning-framework-involving-eeg-based-functional-connectivity-to-diagnose-major-depressive-disorder-mdd
#18
Wajid Mumtaz, Syed Saad Azhar Ali, Mohd Azhar Mohd Yasin, Aamir Saeed Malik
Major depressive disorder (MDD), a debilitating mental illness, could cause functional disabilities and could become a social problem. An accurate and early diagnosis for depression could become challenging. This paper proposed a machine learning framework involving EEG-derived synchronization likelihood (SL) features as input data for automatic diagnosis of MDD. It was hypothesized that EEG-based SL features could discriminate MDD patients and healthy controls with an acceptable accuracy better than measures such as interhemispheric coherence and mutual information...
July 13, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28702717/mindfulness-based-stress-reduction-and-group-support-decrease-stress-in-adolescents-with-cardiac-diagnoses-a-randomized-two-group-study
#19
Vicki A Freedenberg, Pamela S Hinds, Erika Friedmann
Adolescents with cardiac diagnoses face unique challenges that can cause psychosocial distress. This study compares a Mindfulness-Based Stress Reduction (MBSR) program to a video online support group for adolescents with cardiac diagnoses. MBSR is a structured psycho-educational program which includes yoga, meditation, cognitive restructuring, and group support. A published feasibility study by our group showed significant reduction in anxiety following this intervention. Participants were randomized to MBSR or video online support group, and completed measures of anxiety, depression, illness-related stress, and coping pre- and post-6-session interventions...
July 12, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28701927/activation-of-the-creb-c-fos-pathway-during-long-term-synaptic-plasticity-in-the-cerebellum-granular-layer
#20
Daniela Gandolfi, Silvia Cerri, Jonathan Mapelli, Mariarosa Polimeni, Simona Tritto, Marie-Therese Fuzzati-Armentero, Albertino Bigiani, Fabio Blandini, Lisa Mapelli, Egidio D'Angelo
The induction of long-term potentiation and depression (LTP and LTD) is thought to trigger gene expression and protein synthesis, leading to consolidation of synaptic and neuronal changes. However, while LTP and LTD have been proposed to play important roles for sensori-motor learning in the cerebellum granular layer, their association with these mechanisms remained unclear. Here, we have investigated phosphorylation of the cAMP-responsive element binding protein (CREB) and activation of the immediate early gene c-Fos pathway following the induction of synaptic plasticity by theta-burst stimulation (TBS) in acute cerebellar slices...
2017: Frontiers in Cellular Neuroscience
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