keyword
https://read.qxmd.com/read/33055321/prognostic-parameters-of-the-susceptibility-of-staphylococcus-spp-to-aminoglycosides-and-doxycycline
#1
JOURNAL ARTICLE
Oleksandr A Nazarchuk, Vasyl I Nahaichuk, Neonila I Osadchuk, Dmytro V Dmytriiev, Kostiantyn D Dmytriiev, Oksana S Turzhanska
OBJECTIVE: The aim: To perform microbiological investigation and analytic mathematic prediction of clinical isolates of S. aureus to aminoglycosides in patients with severe burns. PATIENTS AND METHODS: Materials and methods: We analyzed resistance of 199 S. aureus strains to aminoglycosides (gentamicin, tobramycin and amikacin) and doxycycline from 435 patients treated in the regional hospital due to burns for the period from 2011-2017. RESULTS: Results: We created predictive curves for the prediction of susceptibility of S...
2020: WiadomoĊ›ci Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://read.qxmd.com/read/29934910/predictive-systems-toxicology
#2
REVIEW
Narsis A Kiani, Ming-Mei Shang, Hector Zenil, Jesper Tegner
In this review we address to what extent computational techniques can augment our ability to predict toxicity. The first section provides a brief history of empirical observations on toxicity dating back to the dawn of Sumerian civilization. Interestingly, the concept of dose emerged very early on, leading up to the modern emphasis on kinetic properties, which in turn encodes the insight that toxicity is not solely a property of a compound but instead depends on the interaction with the host organism. The next logical step is the current conception of evaluating drugs from a personalized medicine point of view...
2018: Methods in Molecular Biology
https://read.qxmd.com/read/22630092/paraffin-based-immunohistochemistry-in-the-evaluation-of-glomerular-diseases-in-renal-biopsies
#3
JOURNAL ARTICLE
Muhammad Usman Rathore, Muhammad Tahir Khadim, Sajid Mushtaq, Muhammad Atique
OBJECTIVE: To determine sensitivity and specificity of paraffin-based immunohistochemistry in the evaluation of glomerular diseases in renal biopsies using immunofluorescence as gold standard. STUDY DESIGN: Cross-sectional analytical study. PLACE AND DURATION OF STUDY: Department of Histopathology, Armed Forces Institute of Pathology, Rawalpindi, from August 2008 to August 2009. METHODOLOGY: Seventy renal biopsy specimens fulfilling the inclusion criteria for light microscopy and immunofluorescence during the study period were evaluated...
June 2012: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
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