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Intraventricular hemorrhage

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https://www.readbyqxmd.com/read/29234148/quality-improvement-to-reduce-chronic-lung-disease-rates-in-very-low-birth-weight-infants-high-compliance-with-a-respiratory-care-bundle-in-a-small-nicu
#1
Zuzanna Kubicka, Eyad Zahr, Tamara Rousseau, Henry A Feldman, John Fiascone
OBJECTIVE: Reduce chronic lung disease by 10% among very-low birth weight infants by implementing a consistent respiratory care bundle. STUDY DESIGN: Prospective quality improvement study of infants below 32 weeks gestation in a small neonatal intensive care unit. A respiratory care bundle to eliminate inter-provider variability and minimize use of mechanical ventilation was implemented. This included: defining delivery room management with use of continuous positive airway pressure/nasal intermittent positive pressure ventilation, uniform intubation/extubation criteria, and standardizing ventilation/post-extubation support...
December 12, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29220639/early-lumbar-puncture-and-risk-of-intraventricular-hemorrhage-in-very-low-birth-weight-infants
#2
Daniela Testoni, Christoph P Hornik, Ruth Guinsburg, Reese H Clark, Rachel G Greenberg, Daniel K Benjamin, P Brian Smith
BACKGROUND: Lumbar puncture (LP) is the gold standard for diagnosing meningitis; however it is unknown whether early LP (≤3days of life) is associated with increased risk of intraventricular hemorrhage (IVH) in very low birth weight (VLBW) infants. OBJECTIVE: To determine whether early LP in VLBW infants is associated with severe IVH. METHODS: VLBW infants from a cohort of 1,158,789 infants discharged from 382 neonatal intensive care units (1997-2015) were enrolled...
December 5, 2017: Early Human Development
https://www.readbyqxmd.com/read/29216502/intraventricular-hemorrhage-related-to-avm-rupture-description-outcomes-and-impact-of-intraventricular-fibrinolysis
#3
Vianney Gilard, Thomas Metayer, Clement Gakuba, Olivier Langlois, François Proust, Evelyne Emery, Thomas Gaberel
OBJECTIVES: Arteriovenous malformation (AVM) rupture could lead to intraventricular hemorrhage (IVH), a particularly severe form of intracranial bleeding. The epidemiology, presentation, management and outcomes of IVH related to AVM rupture have not been clearly addressed yet. The aim of the present study was to investigate the characteristics of IVH related to AVM rupture, with particular attention paid to functional outcomes and to the impact of intraventricular fibrinolysis (IVF). PATIENTS AND METHODS: Between 2011 and 2015, all patients suffering from IVH admitted in two tertiary neurosurgical centers were included in a prospective register...
December 4, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29215136/spontaneous-intracerebral-hemorrhage-as-presentation-of-atypical-central-neurocytoma-the-role-of-angiogenesis-through-the-characterization-of-tumor-endothelial-cells
#4
Giovanni Marfia, Elena Pirola, Stefania Elena Navone, Matteo Beretta, Laura Guarnaccia, Elena Trombetta, Andrea Franzini, Paolo Rampini, Rolando Campanella
A 36-year-old white man presented with sudden-onset headache and rapid deterioration of consciousness. Computer tomography revealed a right capsular intra-parenchimal hemorrhage with an intraventricular component; therefore, emergency surgery was performed. Once the hematoma was evacuated, the cause of the hemorrhage was identified as a tumor mass and it was resected. Histopathological and immunohistochemical examinations of the surgical specimen disclosed a diagnosis of atypical central neurocytoma. By using a protocol recently set up in our laboratory, we succeeded in isolating and propagating, for the first time, human endothelial cells from central neurocytoma (CN-ECs)...
December 7, 2017: Histology and Histopathology
https://www.readbyqxmd.com/read/29210924/intraventricular-hemorrhage-in-moderate-to-severe-congenital-heart-disease
#5
Cynthia M Ortinau, Jagruti S Anadkat, Christopher D Smyser, Pirooz Eghtesady
OBJECTIVES: Determine the prevalence of intraventricular hemorrhage in infants with moderate to severe congenital heart disease, investigate the impact of gestational age, cardiac diagnosis, and cardiac intervention on intraventricular hemorrhage, and compare intraventricular hemorrhage rates in preterm infants with and without congenital heart disease. DESIGN: A single-center retrospective review. SETTING: A tertiary care children's hospital...
November 28, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29209884/congenital-obstruction-of-foramen-of-monro-report-of-10-patients-and-literature-review
#6
Shima Shahjouei, Zohreh Habibi, Soheil Naderi, Ramin Mahmoodi, Farideh Nejat
INTRODUCTION: A wide spectrum of etiologies can obstruct foramen of Monro (FOM) and result in hydrocephalus. Congenital occlusion of FOM is a rare entity which may present either in childhood or in adulthood. METHODS: Between 2007 and 2016, we screened all pediatric patients with hydrocephalus of either one or both lateral ventricles. Congenital occlusion of FOM was confirmed in the absence of masses occupying the FOM, prenatal or postnatal central nervous system (CNS) infections, intraventricular hemorrhage, previous cerebral intervention, or associated CNS anomalies affecting the flow of cerebrospinal fluid (CSF)...
December 5, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29204009/outcome-of-early-versus-delayed-evacuation-of-spontaneous-lobar-hematomas-in-unconscious-adults
#7
Hazem M Alkosha, Wael K Zakaria
Objective: To explore the difference in outcomes of medium-sized lobar hematomas evacuated in early versus delayed fashion among unconscious noncomatose individuals. Methods: A retrospective analysis of demographic, clinical, and radiological data of unconscious patients admitted with lobar hematomas during 18 years was performed. Time to surgery was compared in various patient variables and characteristics. Outcome groups (favorable and poor) were also compared to find out any association with surgery timing, as well as potential indicators of outcome and mortality...
October 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29201849/concurrent-surgery-of-craniectomy-and-splenectomy-as-initial-treatment-in-severe-traumatic-head-injury-a-case-report
#8
Hyeong Rae Lee, Nam Kyu You, Sook Jin Seo, Mi Sun Choi
It is not a common case for neurosurgery department and the other departments to perform joint operation at the same time. Patients with severe head injury are a condition in which vital signs are unstable due to severe brain swelling and increased intracranial pressure, and emergency surgery is required. A 44-year-old man visited the trauma center with a motorcycle accident. The Glasgow Coma Scale score at the time of emergency department was 3 points, and the pupil was fixed at 6 mm on both sides. His medical history was unknown...
October 2017: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/29194369/elevated-systemic-il-6-levels-in-patients-with-aneurysmal-subarachnoid-hemorrhage-is-an-unspecific-marker-for-post-sah-complications
#9
Shafqat Rasul Chaudhry, Birgit Stoffel-Wagner, Thomas Mehari Kinfe, Erdem Güresir, Hartmut Vatter, Dirk Dietrich, Alf Lamprecht, Sajjad Muhammad
Background: Aneurysmal subarachnoid hemorrhage (aSAH) is still a fatal and morbid disease, although bleeding aneurysms can be secured in almost all cases. Occurrence of post-SAH complications including cerebral vasospasm, delayed cerebral ischemia, hydrocephalus, epilepsy, and infections are the main determinants of clinical outcome. Hence, it is important to search for early predictors for specific post-SAH complications to treat these complications properly. Both cellular and molecular (cytokines) inflammation play a key role after aSAH during the phase of occurrence of post-SAH complications...
December 1, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29192863/precipitating-hydrophobic-injectable-liquid-embolization-of-intracranial-vascular-shunts-initial-experience-and-technical-note
#10
Shriram Varadharajan, Arvinda Hanumanthapura Ramalingaiah, Jitender Saini, Arun Kumar Gupta, B Indira Devi, Ullas V Acharya
Precipitating hydrophobic injectable liquid (PHIL) is a newly available liquid embolic agent for endovascular therapy. It is nonadhesive and composed of a biocompatible polymer dissolved in dimethyl sulfoxide solvent and bonded covalently with iodine. In this report, the authors present their preliminary experience using PHIL in the treatment of intracranial vascular shunts. Between July 2015 and December 2015, 11 patients underwent endovascular embolization using the PHIL embolic agent. Five patients had arteriovenous malformations, 4 had dural arteriovenous fistulas, 1 patient had a carotid-cavernous fistula, and 1 patient had a pial arteriovenous fistula...
December 1, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29192634/the-pattern-of-significant-lesions-found-in-computerized-tomography-scan-of-recurrent-seizure-patients-at-a-center-in-enugu-nigeria
#11
A B Ezeala-Adikaibe, S C Ohaegbulam, C A Ndubuisi
INTRODUCTION: Seizures are common reasons for neurologic consultations and investigations. In the absence of magnetic resonance imaging, computerized tomography scanning of the brain is a reliable and cheaper alternative. Little is known about the pattern of brain lesions in patients with recurrent seizures in Nigeria. OBJECTIVES: To determine the pattern of significant intracerebral lesions in patients presenting with recurrent seizures in a tertiary hospital in Enugu...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29187166/what-is-the-safest-mode-of-delivery-for-extremely-preterm-cephalic-non-cephalic-twin-pairs-a-systematic-review-and-meta-analyses
#12
Catherine Dagenais, Anne-Mary Lewis-Mikhael, Marinela Grabovac, Amit Mukerji, Sarah D McDonald
BACKGROUND: Given the controversy around mode of delivery, our objective was to assess the evidence regarding the safest mode of delivery for actively resuscitated extremely preterm cephalic/non-cephalic twin pairs before 28 weeks of gestation. METHODS: We searched Cochrane CENTRAL, MEDLINE, EMBASE and  http://clinicaltrials.gov from January 1994 to January 2017. Two reviewers independently screened titles, abstracts and full text articles, extracted data and assessed risk of bias...
November 29, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29186106/late-preterm-prelabor-rupture-of-fetal-membranes-fetal-inflammatory-response-and-neonatal-outcome
#13
Ivana Musilova, Ctirad Andrys, Marcela Drahosova, Barbora Zednikova, Helena Hornychova, Lenka Pliskova, Helena Zemlickova, Bo Jacobsson, Marian Kacerovsky
OBJECTIVES: To characterize the influence of microbial invasion of the amniotic cavity (MIAC) and/or intra-amniotic inflammation (IAI) on the intensity of the fetal inflammatory response and the association between the presence of the fetal inflammatory response syndrome (FIRS) and short-term neonatal morbidity in the preterm prelabor rupture of membranes (PPROM) between the gestational ages of 34 and 37 weeks. METHODS: One hundred and fifty-nine women were included in the study...
November 28, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29184717/intraventricular-hemorrhage-possibly-extending-from-an-infratentorial-subdural-hematoma-via-a-perforated-suprapineal-recessus-in-a-full-term-neonate
#14
Yoichiro Serita, Takato Morioka, Nobuya Murakami, Nobuko Kawamura, Yasushi Takahata, Ryutaro Kira
Background: Although intraventricular hemorrhage (IVH) is very rarely reported in full-term neonates, it may occur in children with perinatal trauma, asphyxia, and coagulation disorders, and may originate in the choroid plexus and residual subependymal germinal matrix layer. Case Description: We present the case of a full-term baby with IVH. She had no perinatal problems or coagulation disorders. Sagittal views of neuroimages demonstrated that the IVH possibly extended from a subdural hemorrhage (SDH) in the infratentorial area via a perforated suprapineal recessus...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/29184588/clinical-outcomes-of-high-risk-infant-follow-up-program-in-a-tertiary-care-centre
#15
Kayvan Mirnia, Forouzan Akrami, Behzad Jodeiry, Mohammad Heidarzadeh, Sima Safavinia
Background: High-risk infant follow-up (HRIF) program is necessary for early detection, timely intervention, and promotion of health outcomes in vulnerable infants, ethically. The present study was carried out to assess the clinical outcomes of the HRIF Program in Alzahra hospital as a tertiary care centre, in Iran. Materials and Methods: In this cohort study, 5840 neonates were born at Alzahra hospital, from June 1, 2011 to 30th February 2012. Among those who were admitted to neonatal intensive care unit (NICU), 253 infants were recruited by census according to HRIs criteria...
November 2017: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/29181530/neurodevelopmental-and-behavioral-outcomes-in-extremely-premature-neonates-with-ventriculomegaly-in-the-absence-of-periventricular-intraventricular-hemorrhage
#16
Athina Pappas, Ira Adams-Chapman, Seetha Shankaran, Scott A McDonald, Barbara J Stoll, Abbot R Laptook, Waldemar A Carlo, Krisa P Van Meurs, Susan R Hintz, Martha D Carlson, Jane E Brumbaugh, Michele C Walsh, Myra H Wyckoff, Abhik Das, Rosemary D Higgins
Importance: Studies of cranial ultrasonography and early childhood outcomes among cohorts of extremely preterm neonates have linked periventricular-intraventricular hemorrhage and cystic periventricular leukomalacia with adverse neurodevelopmental outcomes. However, the association between nonhemorrhagic ventriculomegaly and neurodevelopmental and behavioral outcomes is not fully understood. Objective: To characterize the outcomes of extremely preterm neonates younger than 27 weeks' gestational age who experienced nonhemorrhagic ventriculomegaly that was detected prior to 36 weeks' postmenstrual age...
November 27, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/29181317/a-predictive-score-for-retinopathy-of-prematurity-by-using-clinical-risk-factors-and-serum-insulin-like-growth-factor-1-levels
#17
Yeşim Coşkun, Ceyhun Dalkan, Özge Yabaş, Özlem Ünay Demirel, Elif Samiye Bayar, Sibel Sakarya, Tuba Müftüoğlu, Dilaver Erşanlı, Nerin Bahçeciler, İpek Akman
AIM: To detect the impact of insulin-like growth factor-1 (IGF-1) and other risk factors for the early prediction of retinopathy of prematurity (ROP) and to establish a scoring system for ROP prediction by using clinical criteria and serum IGF-1 levels. METHODS: The study was conducted with 127 preterm infants. IGF-1 levels in the 1st day of life, 1st, 2nd, 3rd and 4th week of life was analyzed. The score was established after logistic regression analysis, considering the impact of each variable on the occurrences of any stage ROP...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29179524/predictors-of-hematoma-expansion-predictors-after-intracerebral-hemorrhage
#18
REVIEW
Sheng Chen, Binjie Zhao, Wei Wang, Ligen Shi, Cesar Reis, Jianmin Zhang
Despite years of effort, intracerebral hemorrhage (ICH) remains the most devastating form of stroke with more than 40% 30-day mortality worldwide. Hematoma expansion (HE), which occurs in one third of ICH patients, is strongly predictive of worse prognosis and potentially preventable if high-risk patients were identified in the early phase of ICH. In this review, we summarize data from recent studies on HE prediction and classify those potential indicators into four categories: clinical (severity of consciousness disturbance; blood pressure; blood glucose at and after admission); laboratory (hematologic parameters of coagulation, inflammation and microvascular integrity status), radiographic (interval time from ICH onset; baseline volume, shape and density of hematoma; intraventricular hemorrhage; especially the spot sign and modified spot sign) and integrated predictors (9-point or 24-point clinical prediction algorithm and PREDICT A/B)...
October 24, 2017: Oncotarget
https://www.readbyqxmd.com/read/29173788/non-steroidal-anti-inflammatory-drugs-in-newborns-and-infants
#19
REVIEW
Jacob V Aranda, Fabrizio Salomone, Gloria B Valencia, Kay D Beharry
Nonsteroidal antiinflammatory drugs (NSAIDs) and acetaminophen are used in young infants and newborns for pain and fever control, patent ductus closure, prevention of intraventricular hemorrhage, and potentially for prevention of retinopathy of prematurity. These drugs inhibit cyclooxygenase 1 (COX-1), COX-2, and peroxidases, thus, blocking prostaglandin (PG) synthesis. PGs are eicosanoids that regulate several physiologic, pathologic, and cellular processes, including vasomotor tone, platelet aggregation, sensitization of neurons to pain, and many molecular events critical to physiologic homeostasis...
December 2017: Pediatric Clinics of North America
https://www.readbyqxmd.com/read/29171121/insular-damage-new-onset-atrial-fibrillation-and-outcome-after-acute-intracerebral-hemorrhage
#20
L Prats-Sánchez, D Guisado-Alonso, C Painous, F Fayos, E Pascual-Goñi, R Delgado-Mederos, A Martínez-Domeño, P Camps-Renom, J Martí-Fàbregas
BACKGROUND: Cortical insular damage is associated with cardiac arrhythmias and an increased risk of death. We investigated the influence of insular damage on the outcome of patients with acute intracerebral hemorrhage (ICH) as well as the frequency and predictors of new-onset atrial fibrillation (nAF). METHODS: We studied consecutive patients with ICH from 2013 to 2016. We identified those patients who underwent continuous electrocardiographic monitoring (≥24 hours), known AF and recent ischemic stroke...
November 24, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
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