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Intraventricular hemorrhage

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https://www.readbyqxmd.com/read/29673614/lacunar-stroke-cavernous-angioma-and-fusiform-aneurysm-due-to-irradiation-for-pilocytic-astrocytoma-a-case-report
#1
Maruyama Kunitaka, Takuya Akai, Naoki Akioka, Takahiro Tomita, Shoichi Nagai, Satoshi Kuroda
Radiotherapy is a useful modality for the treatment of brain tumors, but may induce brain degeneration, tumor formation, and vasculopathy in the irradiated field. We describe a rare case of a pediatric patient who presented multiple different types of vascular events consecutively in the irradiated field including lacunar stroke because of occlusion of perforating artery, intraventricular hemorrhage from cavernoma, and subarachnoid hemorrhage because of the rupture of fusiform aneurysm, 6 years after radiotherapy against pilocytic astrocytoma...
April 16, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29669357/oxygenation-of-the-immature-infant-a-commentary-and-recommendations-for-oxygen-saturation-targets-and-alarm-limits
#2
Ola Didrik Saugstad
BACKGROUND: For 70 years, there has been a search for the optimal oxygenation of premature infants. In spite of the lack of evidence, guidelines have successively reduced oxygenation targets during these years. OBJECTIVES: (1) To present a summary of previously published meta-analyses of 5 randomized studies (NeOProM) which tested a low (85-89%) versus a high (91-95%) oxygen saturation target the first weeks after birth on outcome of immature newborn infants. (2) To present international recommendations for oxygenation the first weeks after birth...
April 18, 2018: Neonatology
https://www.readbyqxmd.com/read/29666163/neurodevelopmental-impairment-among-extremely-preterm-infants-in-the-neonatal-research-network
#3
Ira Adams-Chapman, Roy J Heyne, Sara B DeMauro, Andrea F Duncan, Susan R Hintz, Athina Pappas, Betty R Vohr, Scott A McDonald, Abhik Das, Jamie E Newman, Rosemary D Higgins
OBJECTIVES: Evaluate the spectrum of neurodevelopmental outcome in a contemporary cohort of extremely preterm infants. We hypothesize that the rate of severe neurodevelopmental impairment (NDI) decreases over time. METHODS: Retrospective analysis of neurodevelopmental outcome of preterm infants ≤27 weeks' gestational age (GA) from a Neonatal Research Network center that completed neurodevelopmental follow-up assessments between April 1, 2011, and January 1, 2015...
April 17, 2018: Pediatrics
https://www.readbyqxmd.com/read/29650786/association-of-quantified-location-specific-blood-volumes-with-delayed-cerebral-ischemia-after-aneurysmal-subarachnoid-hemorrhage
#4
W E van der Steen, I A Zijlstra, D Verbaan, A M M Boers, C S Gathier, R van den Berg, G J E Rinkel, B A Coert, Y B W E M Roos, C B L M Majoie, H A Marquering
BACKGROUND AND PURPOSE: Delayed cerebral ischemia is a severe complication of aneurysmal SAH and is associated with a high case morbidity and fatality. The total blood volume and the presence of intraventricular blood on CT after aneurysmal SAH are associated with delayed cerebral ischemia. Whether quantified location-specific (cisternal, intraventricular, parenchymal, and subdural) blood volumes are associated with delayed cerebral ischemia has been infrequently researched. This study aimed to associate quantified location-specific blood volumes with delayed cerebral ischemia...
April 12, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29627178/growth-morbidity-in-extremely-low-birth-weight-survivors-of-necrotizing-enterocolitis-at-discharge-and-two-year-follow-up
#5
Charles R Hong, Brenna S Fullerton, Charles E Mercier, Kate A Morrow, Erika M Edwards, Karla R Ferrelli, Roger F Soll, Biren P Modi, Jeffrey D Horbar, Tom Jaksic
PURPOSE: The purpose of this study was to examine postnatal growth outcomes and predictors of growth failure at 18-24months corrected age among extremely low birth weight (ELBW) survivors of necrotizing enterocolitis (NEC) compared to survivors without NEC. METHODS: Data were collected prospectively on ELBW (22-27weeks gestation or 401-1000g birth weight) infants born 2000-2013 at 46 centers participating in the Vermont Oxford Network follow-up project. Severe growth failure was defined as <3rd percentile weight-for-age...
March 8, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29624572/maternal-body-mass-index-and-risk-of-intraventricular-hemorrhage-in-preterm-infants
#6
Vidya V Pai, Suzan L Carmichael, Peiyi Kan, Stephanie A Leonard, Henry C Lee
BACKGROUND: Intraventricular hemorrhage (IVH) and pre-pregnancy obesity and underweight have been linked to inflammatory states. We hypothesize that IVH in preterm infants is associated with pre-pregnancy obesity and underweight due to an inflammatory intrauterine environment. METHODS: Population-based study of infants born between 22 and 32 weeks' gestation from 2007 to 2011. Data were extracted from vital statistics and the California Perinatal Quality Care Collaborative...
April 6, 2018: Pediatric Research
https://www.readbyqxmd.com/read/29622558/characteristic-mr-imaging-findings-of-the-neonatal-brain-in-rasopathies
#7
M N Cizmeci, M Lequin, K D Lichtenbelt, D Chitayat, P Kannu, A G James, F Groenendaal, E Chakkarapani, S Blaser, L S de Vries
BACKGROUND AND PURPOSE: Neuroimaging features in neonates with RASopathies are rarely reported, and to date, there are no neuroimaging studies conducted in this population. Our aim was to investigate the occurrence of supratentorial and posterior fossa abnormalities on brain MRIs of neonates with a RASopathy. MATERIALS AND METHODS: An observational case-control study of neonates with a confirmed RASopathy was conducted. The presence of an intraventricular and/or parenchymal hemorrhage and punctate white matter lesions and assessments of the splenium of the corpus callosum, gyrification of the cortical gray matter, and enlargement of the extracerebral space were noted...
April 5, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29615483/incidence-of-hypocapnia-hypercapnia-and-acidosis-and-the-associated-risk-of-adverse-events-in-preterm-neonates
#8
Melissa K Brown, Deborah M Poeltler, Kasim O Hassen, Danielle V Lazarus, Vanessa K Brown, Jeremiah J Stout, Wade D Rich, Anup C Katheria
BACKGROUND: Permissive hypercapnia is a lung-protection strategy. We sought to review our current clinical practice for the range of permissive hypercapnia and identify the relationship between P aCO2 and pH and adverse outcomes. METHODS: A secondary analysis of a delayed cord-clamping clinical trial was performed on all arterial blood gas tests in the first 72 h in infants < 32 weeks gestational age. All arterial blood gas values were categorized into a clinical range to determine the percent likelihood of occurring in the total sample...
April 3, 2018: Respiratory Care
https://www.readbyqxmd.com/read/29614567/-predictive-factors-of-mortality-in-extremely-preterm-infants
#9
L Lin, M C Fang, H Jiang, M L Zhu, S Q Chen, Z L Lin
Objective: To investigate the predictive factors of mortality in extremely preterm infants. Methods: The retrospective case-control study was accomplished in the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University. A total of 268 extremely preterm infants seen from January 1, 1999 to December 31, 2015 were divided into survival group (192 cases) and death group (76 cases). The potential predictive factors of mortality were identified by univariate analysis, and then analyzed by multivariate unconditional Logistic regression analysis...
April 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29610829/association-of-histologic-chorioamnionitis-with-perinatal-brain-injury-and-early-childhood-neurodevelopmental-outcomes-among-preterm-neonates
#10
Daniel Bierstone, Nienke Wagenaar, Dawn L Gano, Ting Guo, Gregory Georgio, Floris Groenendaal, Linda S de Vries, Jojy Varghese, Hannah C Glass, Catherine Chung, Jefferson Terry, Maarten Rijpert, Ruth E Grunau, Anne Synnes, A James Barkovich, Donna M Ferriero, Manon Benders, Vann Chau, Steven P Miller
Importance: Understanding the role of chorioamnionitis, a major factor leading to preterm birth, in the pathogenesis of neonatal brain injury and adverse neurodevelopmental outcomes may help in identifying potentially modifiable perinatal variables affecting brain health and outcomes among children born preterm. Objective: To evaluate whether histologic chorioamnionitis among neonates born very preterm is associated with intraventricular hemorrhage (IVH) and punctate white matter injury (WMI) or with adverse neurodevelopmental outcomes during early childhood...
April 2, 2018: JAMA Pediatrics
https://www.readbyqxmd.com/read/29606108/prevalence-and-risk-factors-of-retinopathy-of-prematurity-in-iran-a-systematic-review-and-meta-analysis
#11
Milad Azami, Zahra Jaafari, Shoboo Rahmati, Afsar Dastjani Farahani, Gholamreza Badfar
BACKGROUND: Retinopathy of prematurity (ROP) refers to the developmental disorder of the retina in premature infants and is one of the most serious and most dangerous complications in premature infants. The prevalence of ROP in Iran is different in various parts of Iran and its prevalence is reported to be 1-70% in different regions. This study aims to determine the prevalence and risk factors of ROP in Iran. METHODS: This review article was conducted based on the preferred reporting items for systematic review and meta-analysis (PRISMA) protocols...
April 2, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29603412/improving-nutrition-outcomes-for-infants-1500-grams-with-a-progressive-evidenced-based-enteral-feeding-protocol
#12
Melissa K Thoene, Elizabeth Lyden, Ann Anderson-Berry
BACKGROUND: Growth is essential for very low birth weight infants. The purpose of this retrospective chart review was to evaluate the impact of a new standardized, evidenced-based feeding protocol for infants born < 1500 g in correlation with growth and clinical outcomes. METHODS: Growth and nutrition data was reviewed from 2 groups of infants born < 1500 g within a level III newborn intensive care unit (NICU). Epoch 1 infants (N = 32) received care following initial implementation of a standardized enteral feeding protocol...
March 30, 2018: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29602923/-the-role-of-genes-of-renin-angiotensin-system-in-the-development-of-adverse-outcomes-of-treatment-in-severe-intraventricular-hemorrhages-in-premature-infants
#13
Наталия И Гасюк, Наталия С Артемова, Елена М Ковалева, Валерий И Похилько, Галина А Соловьева
OBJECTIVE: Introduction: Intraventricular hemorrhage (IVH) causes increased morbidity and mortality in premature infants and is associated with adverse neurological outcomes. The aim of the research is to confirm the role of genes of renin-angiotensin system in the development of adverse outcomes of treatment of severe IVC in preterm. PATIENTS AND METHODS: Materials and methods: A prospective study was conducted, which included 58 premature infants (average birth weight 1016...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29600511/increased-cerebral-blood-flow-on-arterial-spin-labeling-magnetic-resonance-imaging-can-localize-to-seizure-focus-in-newborns-a-report-of-3-cases
#14
Patrick Mabray, Rapeepat Thewamit, Matthew T Whitehead, Amy Kao, Joseph Scafidi, William D Gaillard, Taeun Chang, Tammy N Tsuchida
Arterial spin labeling (ASL) magnetic resonance imaging (MRI) can assess cerebral blood flow (CBF) without using radiolabeled tracers. It is unknown whether regional increases in CBF on ASL MRI correlate with seizure location in newborns. We report 3 newborns with focal seizures localized on continuous video electroencephalogram (cEEG), anatomical brain MRI, and ASL MRI. Each patient underwent pseudocontinuous ASL with segmented 3-dimensional fast spin echo readout as part of standard care. Case 1 is a term male infant presenting with left temporal status epilepticus and recurrent cEEG seizures from an idiopathic large left intraventricular hemorrhage...
March 30, 2018: Epilepsia
https://www.readbyqxmd.com/read/29596065/reversible-visual-field-defect-after-isolated-intraventricular-hemorrhage
#15
Youngkook Kim, Bo Young Hong, Joon-Sung Kim
No abstract text is available yet for this article.
March 28, 2018: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29594812/neutrophil-to-lymphocyte-ratio-is-an-independent-predictor-of-30-day-mortality-of-intracerebral-hemorrhage-patients-a-validation-cohort-study
#16
Fei Wang, Li Wang, Ting-Ting Jiang, Jian-Jun Xia, Feng Xu, Li-Juan Shen, Wen-Hui Kang, Yong Ding, Li-Xia Mei, Xue-Feng Ju, Shan-You Hu, Xiao Wu
In a previous study in patients with intracranial hemorrhage (ICH), we found an association between high neutrophil-to-lymphocyte ratio (NLR) with poor short-term mortality. In the current study, this preliminary finding was validated using an independent patient cohort. A total of 181 ICH patients (from January 2016 to December 2017) were included. Diagnosis was confirmed using computed tomography (CT) in all cases. Patient survival (up to 30 days) was compared between subjects with high NLR (above the 7...
March 28, 2018: Neurotoxicity Research
https://www.readbyqxmd.com/read/29594703/risk-factors-for-shunt-dependency-in-patients-suffering-from-spontaneous-non-aneurysmal-subarachnoid-hemorrhage
#17
Patrick Schuss, Alexis Hadjiathanasiou, Simon Brandecker, Christian Wispel, Valeri Borger, Ági Güresir, Hartmut Vatter, Erdem Güresir
Patients presenting with spontaneous, non-aneurysmal subarachnoid hemorrhage (SAH) achieve better outcomes compared to patients with aneurysmal SAH. Nevertheless, some patients develop shunt-dependent hydrocephalus during treatment course. We therefore analyzed our neurovascular database to identify factors determining shunt dependency after non-aneurysmal SAH. From 2006 to 2016, 131 patients suffering from spontaneous, non-aneurysmal SAH were admitted to our department. Patients were stratified according to the distribution of cisternal blood into patients with perimesencephalic SAH (pSAH) versus non-perimesencephalic SAH (npSAH)...
March 29, 2018: Neurosurgical Review
https://www.readbyqxmd.com/read/29589328/influence-of-bleeding-pattern-on-ischemic-lesions-after-spontaneous-hypertensive-intracerebral-hemorrhage-with-intraventricular-hemorrhage
#18
Lucia Rivera-Lara, Santosh B Murthy, Saman Nekoovaght-Tak, Hasan Ali, Nichol McBee, Rachel Dlugash, Malathi Ram, Richard Thompson, Issam A Awad, Daniel F Hanley, Wendy C Ziai
BACKGROUND: Concomitant acute ischemic lesions are detected in up to a quarter of patients with spontaneous intracerebral hemorrhage (ICH). Influence of bleeding pattern and intraventricular hemorrhage (IVH) on risk of ischemic lesions has not been investigated. METHODS: Retrospective study of all 500 patients enrolled in the CLEAR III randomized controlled trial of thrombolytic removal of obstructive IVH using external ventricular drainage. The primary outcome measure was radiologically confirmed ischemic lesions, as reported by the Safety Event Committee and confirmed by two neurologists...
March 27, 2018: Neurocritical Care
https://www.readbyqxmd.com/read/29588235/a-comparison-of-computed-tomography-based-scales-with-and-without-consideration-of-the-presence-or-absence-of-intraventricular-hemorrhage-in-patients-with-aneurysmal-subarachnoid-hemorrhage
#19
Tetsuji Inagawa, Masaaki Shibukawa, Toshikazu Hidaka
OBJECTIVE: There has been controversy as to whether intraventricular hemorrhage (IVH) after aneurysmal subarachnoid hemorrhage (SAH) contributes to angiographic cerebral vasospasm (aCV) and delayed cerebral ischemia (DCI). CT-based SAH scales that did and did not consider IVH were compared in terms of ability to predict aCV, DCI, and outcome. METHODS: We reviewed 390 patients with ruptured aneurysms who had been treated surgically by day 3 by the same surgeon (T...
March 24, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29587767/opportunities-in-posthemorrhagic-hydrocephalus-research-outcomes-of-the-hydrocephalus-association-posthemorrhagic-hydrocephalus-workshop
#20
REVIEW
Jenna E Koschnitzky, Richard F Keep, David D Limbrick, James P McAllister, Jill A Morris, Jennifer Strahle, Yun C Yung
The Hydrocephalus Association Posthemorrhagic Hydrocephalus Workshop was held on July 25 and 26, 2016 at the National Institutes of Health. The workshop brought together a diverse group of researchers including pediatric neurosurgeons, neurologists, and neuropsychologists with scientists in the fields of brain injury and development, cerebrospinal and interstitial fluid dynamics, and the blood-brain and blood-CSF barriers. The goals of the workshop were to identify areas of opportunity in posthemorrhagic hydrocephalus research and encourage scientific collaboration across a diverse set of fields...
March 27, 2018: Fluids and Barriers of the CNS
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