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Intraventricular hemorrhage

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https://www.readbyqxmd.com/read/29037015/comparison-of-spot-sign-blend-sign-and-black-hole-sign-for-outcome-prediction-in-patients-with-intracerebral-hemorrhage
#1
Peter B Sporns, Michael Schwake, André Kemmling, Jens Minnerup, Wolfram Schwindt, Thomas Niederstadt, Rene Schmidt, Uta Hanning
BACKGROUND AND PURPOSE: Blend sign (BS) and black hole sign (BHS) on non-contrast computed tomography (NCCT) and spot sign (SS) on CT-angiography (CTA) are indicators of early hematoma expansion in spontaneous intracerebral hemorrhage (ICH). However, their independent contributions to outcome have not been well explored. METHODS: In this retrospective study, inclusion criteria were: 1) spontaneous ICH and 2) NCCT and CTA performed on admission within 6 hours after onset of symptoms...
September 2017: Journal of Stroke
https://www.readbyqxmd.com/read/29031388/postnatal-rbc-arachidonic-and-docosahexaenoic-acids-deficiencies-are-associated-with-higher-risk-of-neonatal-morbidities-and-mortality-in-preterm-infants
#2
S Fares, M M Sethom, M B Hammami, M Cheour, M Feki, S Hadj-Taieb, S Kacem
Arachidonic (AA) and docosahexaenoic (DHA) acids are essential for the health and development of the neonate. Red blood cell (RBC) fatty acids were analyzed in 583 very low birth weight (VLBW) infants and 274 term infants using capillary gas chromatography. VLBW infants exhibited significantly lower RBC AA (13.0 ± 0.89 vs. 13.5 ± 0.98) and DHA (3.77 ± 0.60 vs. 3.80 ± 0.62), but higher n6:n3 ratio (3.97 ± 0.46 vs. 3.63 ± 0.37) than term infants. In VLBW infants, DHA was lower in those born with small for gestational age (3...
November 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/29026981/a-clinical-scoring-system-to-predict-the-development-of-intraventricular-hemorrhage-ivh-in-premature-infants
#3
Yesim Coskun, Semra Isik, Tevfik Bayram, Kamran Urgun, Sibel Sakarya, Ipek Akman
OBJECTıVE: The aim of this study is to develop a scoring system for the prediction of intraventricular hemorrhage (IVH) in preterm infants in the first 7 days of life. METHODS: A prospective, clinical study was conducted in Bahcesehir University, Medical Park Goztepe Hospital Neonatal Intensive Care Unit, with the enrollment of 144 preterm infants with gestational age between 24 and 34 weeks. All preterms were followed up for IVH after birth until the 4th week of life. The demographic characteristics and clinical risk factors were noted...
October 12, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29026928/-current-treatment-concepts-in-intracerebral-hemorrhage
#4
REVIEW
H B Huttner, J B Kuramatsu
BACKGROUND AND OBJECTIVE: In recent years, various important studies investigating the management of intracerebral hemorrhage (ICH) have been published. However, these have not entered guideline recommendations yet. Therefore, essential results are summarized here and the findings are integrated into current treatment concepts. MATERIALS AND METHODS: Based on a dedicated literature review and the authors' experience, up-to-date and high-quality investigations were identified...
October 12, 2017: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://www.readbyqxmd.com/read/29026673/endoscopic-management-of-a-cavernous-malformation-on-the-floor-of-third-ventricle-and-aqueduct-of-sylvius-technical-case-report-and-review-of-the-literature
#5
Luis Alberto Ortega-Porcayo, Alexander Perdomo-Pantoja, Isaac Jair Palacios-Ortíz, Salomon Cohen Cohen, Juan Pablo González-Mosqueda, Juan Luis Gómez-Amador
BACKGROUND: Intraventricular cavernous malformations are unusual intracranial vascular malformations; their deep anatomical location complicates their surgical management. Microsurgical approaches are the gold standard approaches for the resection of ventricular lesions, however, they imply considerable neurovascular risks. CASE DESCRIPTION: A 51-year-old patient presented with acute headache, diplopia, vertigo, blurred vision, and a depressed level of consciousness...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/29023219/predictors-of-outcome-in-patients-with-pediatric-intracerebral-hemorrhage-development-and-validation-of-a-modified-score
#6
Alexis Guédon, Thomas Blauwblomme, Grégoire Boulouis, Camille Jousset, Philippe Meyer, Manoëlle Kossorotof, Marie Bourgeois, Stéphanie Puget, Michel Zerah, Catherine Oppenheim, Jean-François Meder, Nathalie Boddaert, Francis Brunelle, Christian Sainte-Rose, Olivier Naggara
Purpose To propose and validate a modified pediatric intracerebral hemorrhage (PICH) (mPICH) score and to compare its association with functional outcome to that of the original PICH score. Materials and Methods Data from prospectively included patients were retrospectively analyzed. Consecutive patients with nontraumatic PICH who had undergone clinical follow-up were included. The study population was divided into a development cohort (2008-2012, n = 100) and a validation cohort (2013-2016, n = 43). An mPICH score was developed after variables associated with poor outcome were identified at multivariate analysis (King's Outcome Scale for Childhood Head Injury score < 5a) in the development cohort...
October 12, 2017: Radiology
https://www.readbyqxmd.com/read/29018128/island-sign-an-imaging-predictor-for-early-hematoma-expansion-and-poor-outcome-in-patients-with-intracerebral-hemorrhage
#7
Qi Li, Qing-Jun Liu, Wen-Song Yang, Xing-Chen Wang, Li-Bo Zhao, Xin Xiong, Rui Li, Du Cao, Dan Zhu, Xiao Wei, Peng Xie
BACKGROUND AND PURPOSE: The aim of the study was to investigate the usefulness of the computed tomography (CT) island sign for predicting early hematoma growth and poor functional outcome. METHODS: We included patients with spontaneous intracerebral hemorrhage (ICH) who had undergone baseline CT within 6 hours after ICH symptom onset in our hospital between July 2011 and September 2016. Two readers independently assessed the presence of the island sign on the admission noncontrast CT scan...
October 10, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29016494/maternal-and-neonatal-outcomes-in-indicated-preterm-births-based-on-the-intended-mode-of-delivery
#8
Spencer G Kuper, Rachel A Sievert, Robin Steele, Joseph R Biggio, Alan T Tita, Lorie M Harper
OBJECTIVE: To compare maternal and neonatal outcomes in women who underwent induction of labor or planned cesarean delivery in indicated preterm births before 34 weeks of gestation. METHODS: We conducted a retrospective cohort study of all indicated singleton preterm births (23-34 weeks of gestation) in a tertiary center from 2011 to 2014. The primary maternal outcome was a composite of early postpartum hemorrhage, blood transfusion, operative complications, postpartum complications, and clinical chorioamnionitis...
October 6, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28992723/severe-cerebellar-hemorrhage-following-transverse-sinus-stenting-for-idiopathic-intracranial-hypertension
#9
Pascale Lavoie, Marie-Ève Audet, Jean-Luc Gariepy, Martin Savard, Steve Verreault, Alain Gourdeau, Geneviève Milot, Sylvine Carrondo Cottin
We report a severe adverse event occurring in the course of a cohort study (ISRCTN13784335) aimed at measuring the efficacy and safety of venous stenting in the treatment of patients with medically refractory idiopathic intracranial hypertension (IIH). The patient was a 41-year-old woman who was not overweight, who presented with severe headache, grade 1 bilateral papilledema and transient tinnitus, refractory to medical treatment. Right transverse sinus stenting was successfully performed. Following surgery, the patient's state of consciousness decreased acutely with rapid and progressive loss of brainstem reflex...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28989043/cerebrospinal-fluid-leak-at-percutaneous-exit-of-ventricular-catheter-as-crucial-risk-factor-for-external-ventricular-drainage-related-infection-in-adult-neurosurgical-patients
#10
Jaechan Park, Yeon-Ju Choi, Boram Ohk, Hyun-Ha Chang
OBJECTIVE: The placement of a ventricular catheter for temporary cerebrospinal fluid (CSF) diversion is associated with a considerable risk of CSF infection. The authors investigated the effect of a CSF leak on CSF-related infection and the predisposing factors for a CSF leak. METHODS: Fifty-two patients who underwent external ventricular drainage (EVD) for acute hydrocephalus associated with a subarachnoid hemorrhage (SAH) or intraventricular hemorrhage (IVH) were enrolled in this prospective study...
October 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28987174/raised-intracranial-pressure-and-brain-edema
#11
Ville Leinonen, Ritva Vanninen, Tuomas Rauramaa
Acutely increased intracranial pressure (ICP) is a life-threatening neurosurgical emergency. Optimal management strategy is selected according to the causative process. Typical causes are intracranial bleeds like traumatic subdural, epidural, or intracerebral hematoma (ICH); spontaneous ICH, intraventricular hemorrhage, subarachnoid hemorrhage, and hydrocephalus. When occurring without significant brain injury and treated effectively before herniation, a full recovery can be expected. In intraparenchymal injuries a full recovery is unlikely since dead cells in the central nervous system leave an "empty hole," to be replaced by cerebrospinal fluid...
2017: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/28981078/maternal-magnesium-therapy-neonatal-serum-magnesium-concentration-and-immediate-neonatal-outcomes
#12
D Narasimhulu, A Brown, N M Egbert, M Rojas, S Haberman, A Bhutada, H Minkoff, S Rastogi
OBJECTIVE: The fetus is exposed to magnesium administered to the pregnant mother. However, there is controversy regarding magnesium-related neonatal adverse outcomes, largely driven by a limited understanding of the factors that influence neonatal serum magnesium concentrations and associated outcomes. The objective of this study was to examine the relationship between antenatal maternal magnesium dose and serum concentrations, neonatal serum magnesium concentration and immediate neonatal outcomes...
October 5, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28979727/early-predictors-of-neonatal-intraventricular-hemorrhage
#13
Mohamed Shawky Elfarargy, Mohamed Adel Eltomey, Neama Ali Soliman
OBJECTIVE: Current study aimed toward the early prediction of neonatal intraventricular hemorrhage (IVH) for better management and prognosis. METHODS: This prospective study was conducted on forty neonates at the Neonatal Intensive Care Unit of Pediatrics and Medical Biochemistry department (Tanta University, Egypt) from July 2016 to June 2017. Cord blood erythropoietin and venous blood Activin A were assayed within the first hour of life. Neonates were divided into 2 groups: Group 1 (with IVH) included twenty neonates who developed IVH proved by transcranial ultrasonography (u/s) and Group 2 (without IVH) included twenty neonates who were admitted to the NICU but did not develop IVH, also proved by transcranial u/s...
August 2017: Electronic Physician
https://www.readbyqxmd.com/read/28975005/safety-of-intraventricular-rt-pa-for-pan-ventricular-ivh-caused-by-a-ruptured-avm-a-case-report
#14
Sushrut Dharmadhikari, Ashutosh Mahapatra, Anita Tipirneni, Dileep Yavagal, Amer M Malik
Intraventricular recombinant tissue plasminogen activator (IVT rt-PA) has improved outcomes for intraventricular hemorrhage (IVH). Patients with suspected or untreated arteriovenous malformations (AVMs) have been excluded from clinical trials. We present a patient with IVH secondary to a ruptured AVM safely treated with IVT rt-PA. A 48-year-old Hispanic male with a history of dermatomyositis presented to the emergency department with sudden left-sided weakness. En route to computed tomography (CT), he became lethargic...
October 2017: Neurohospitalist
https://www.readbyqxmd.com/read/28974998/successful-use-of-ketamine-for-central-neurogenic-hyperventilation-a-case-report
#15
G Morgan Jones, Adam L Wiss, Nitin Goyal, Jason J Chang
This report describes the use of ketamine in a patient with central neurogenic hyperventilation following intracerebral hemorrhage. A 41-year-old man was admitted with right thalamic intracerebral hemorrhage with intraventricular extension requiring emergent external ventricular drain placement. After aggressive management of his neurologic status and other associated complications, the patient subacutely developed an altered respiratory pattern characterized by shallow, rapid breaths. After the use of multiple sedative agents to control respiratory drive had failed, a single 2 mg/kg bolus dose of intravenous ketamine was administered...
October 2017: Neurohospitalist
https://www.readbyqxmd.com/read/28973194/shunt-dependent-hydrocephalus-after-aneurysmal-subarachnoid-hemorrhage-predictors-and-long-term-functional-outcomes
#16
Gabriella M Paisan, Dale Ding, Robert M Starke, R Webster Crowley, Kenneth C Liu
BACKGROUND: Although chronic hydrocephalus requiring shunt placement is a known sequela of aneurysmal subarachnoid hemorrhage (aSAH), its effect on long-term functional outcomes is incompletely understood. OBJECTIVE: To identify predictors of shunt-dependent hydrocephalus and shunt complications after aSAH and determine the effect of shunt dependence on functional outcomes in aSAH patients. METHODS: We evaluated a database of patients treated for aSAH at a single center from 2000 to 2015...
July 31, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28972960/strategies-to-enhance-paracrine-potency-of-transplanted-mesenchymal-stem-cells-in-intractable-neonatal-disorders
#17
REVIEW
Won Soon Park, So Yoon Ahn, Se In Sung, Jee-Yin Ahn, Yun Sil Chang
Mesenchymal stem cell (MSC) transplantation represents the next breakthrough in the treatment of currently intractable and devastating neonatal disorders with complex multifactorial etiologies, including bronchopulmonary dysplasia, hypoxic ischemic encephalopathy, and intraventricular hemorrhage. Absent engraftment and direct differentiation of transplanted MSCs, and the 'hit and run' therapeutic effects of these MSCs suggest that their pleiotropic protection might be attributable to paracrine activity via the secretion of various biologic factors rather than to regenerative activity...
October 3, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28964406/diagnosis-and-treatment-of-pericallosal-artery-aneurysms
#18
Guo-Qing Sun, Shi-Gang Jin, Ting-Kai Fu, Xiang-Tao Chen, Zhen Xu
OBJECTIVE: Pericallosal artery aneurysms are not common clinically. The microsurgery and endovascular therapy are surgically challenging operations. The objective of the study is to summarize their clinical symptoms and optimal treatment strategies of pericallosal artery aneurysms. METHODS: Nine cases of pericallosal artery aneurysms detected by digital subtraction angiography (DSA) were reviewed. The clinical manifestation, brain imaging characteristics, and optimal treatment methods were summarized...
September 22, 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/28957424/nutrition-after-preterm-birth-and-adult-neurocognitive-outcomes
#19
Sara Sammallahti, Eero Kajantie, Hanna-Maria Matinolli, Riikka Pyhälä, Jari Lahti, Kati Heinonen, Marius Lahti, Anu-Katriina Pesonen, Johan G Eriksson, Petteri Hovi, Anna-Liisa Järvenpää, Sture Andersson, Katri Raikkonen
BACKGROUND: Preterm birth (<37 gestational weeks) poses a risk of poorer neurocognitive functioning. Faster growth after preterm birth predicts better cognitive abilities and can be promoted through adequate nutrition, but it remains unknown whether variations in nutrient intakes translate into long-term benefits for neurodevelopment. METHODS: In 86 participants of the Helsinki Study of Very Low Birth Weight Adults (birthweight <1500g), we examined if higher intakes of energy, macronutrients, and human milk during the first nine weeks after preterm birth predict performance in tests of cognitive ability at 25...
2017: PloS One
https://www.readbyqxmd.com/read/28949275/assessment-of-cerebrovascular-development-and-intraventricular-hemorrhages-in-preterm-infants-with-optical-measures-of-the-brain-arterial-pulse-wave
#20
Antonio M Chiarelli, Mahdi Mahmoudzadeh, Kathy A Low, Edward L Maclin, Guy Kongolo, Sabrina Goudjil, Monica Fabiani, Fabrice Wallois, Gabriele Gratton
Preterm infants (born at 24-34 weeks of gestational age) suffer from a high incidence of neurological complications. Cerebrovascular lesions (intraventricular hemorrhages, IVH, and ischemic injury) due to the immaturity of the vascular system and its inability to adapt to the extra-uterine environment are the major causes of adverse neurological outcomes. We investigated the feasibility of assessing cerebrovascular status in preterm infants using a novel non-invasive optical procedure, pulse-DOT, usable within the incubator...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
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