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Jorim Anak Ujang, Soon Hong Kwan, Mohd Nazri Ismail, Boon Huat Lim, Rahmah Noordin, Nurulhasanah Othman
BACKGROUND: Excretory-secretory (ES) proteins of E. histolytica are thought to play important roles in the host invasion, metabolism, and defence. Elucidation of the types and functions of E. histolytica ES proteins can further our understanding of the disease pathogenesis. Thus, the aim of this study is to use proteomics approach to better understand the complex ES proteins of the protozoa. METHODS: E. histolytica ES proteins were prepared by culturing the trophozoites in protein-free medium...
2016: Clinical Proteomics
Jessica J Sánchez García, Yanis Toledano-Magaña, Marcos Flores-Alamo, Elena Martínez-Klimova, Rodrigo Galindo-Murillo, Luis F Hernández-Ayala, Luis Ortiz-Frade, Juan C García-Ramos, Elena I Klimova
The reaction of E-2-ferrocenylmethylidenetetralones and E,E-2,6-bis-(ferrocenylmethylidene)-cyclohexanone with 2-aminothiophenol proceed with high diastereoselectivity, forming the ~4.5:1 mixture of trans- and cis-isomers of polycyclic ferrocenylthiazepines, respectively. The reactions of E,E-2,5-bis-(ferrocenylmethylidene)cyclopentanone and E,E-3,5-bis-(ferrocenylmethylidene)-1-methyl-4-piperidone with 2-aminothiophenol take place stereo specifically to form the diastereomeric tricyclic thiazepines of cis- and trans-configuration, respectively...
November 2, 2016: Journal of Inorganic Biochemistry
Manuel Ramiro-H, Omar Vivas
No abstract text is available yet for this article.
November 2016: Revista Médica del Instituto Mexicano del Seguro Social
Carlos Varela-Rueda
No abstract text is available yet for this article.
November 2016: Revista Médica del Instituto Mexicano del Seguro Social
Manuel Ramiro-H, Enrique Cruz-A
Between August 19 and 21, the Feria del Libro de las Ciencias de la Salud (Healthcare Book Fair) took place in the Palacio de Medicina in Mexico City. Archives of Medical Research, Revista Médica del IMSS, and Saber IMSS, three of the main instruments of knowledge diffusion of the Instituto Mexicano del Seguro Social, assisted to this book fair, which was organized by the Facultad de Medicina of UNAM.
November 2016: Revista Médica del Instituto Mexicano del Seguro Social
Elda Karina Guerra-Sáenz, Ángel Gustavo Narváez-Navarro, Ana Cecilia Hernández-López, Judith Bello Saucedo, Griselda Ruiz-Cantú, Paula Cordero-Pérez, María Del Carmen Guevara-Martínez, Linda Elsa Muñoz-Espinosa, Edelmiro Pérez-Rodríguez, Marco Antonio Hernández-Guedea, Homero Zapata-Chavira, Asdrúbal Guevara-Charles, Marlene Marisol Perales-Quintana, Miguel Mariano Escobedo-Villarreal
OBJECTIVE: To assess the knowledge and attitude towards organ donation within health professionals in different institutions of Nuevo Leon. METHODS: A prospective, open, observational, descriptive study of parallel groups, through application of a survey formulated by the Hospital Universitario (HU) "Dr. José Eleuterio González". We applied 208 surveys in the HU (n = 100) and other institutions like IMSS, ISSTE (n = 108). RESULTS: From all the participants, 86% had a positive attitude towards organ donation, associated to a higher education, and information regarding organ donation received by other health professionals...
September 2016: Gaceta Médica de México
Alejandro Figueroa-Lara, Fátima Itzel López-Fernández, Adriana López-Domínguez, German Fajardo-Dolci
OBJECTIVE: To quantify the production capacity and performance in research and technological developments of the Mexican Social Security Institute (IMSS). MATERIAL AND METHODS: We identified and analyzed information of the legislation, human and financial resources, and infrastructure addressed for research and technological development of IMSS. We analyzed whether the information on the legal framework contained key features to boost research and technological development...
September 2016: Gaceta Médica de México
Eunice López-Muñoz, Jorge Antonio Ibarra-Avalos, Rosario Guadalupe Chan-Verdugo, Leovigildo Mateos-Sánchez, Olivia Sánchez-Rodríguez
In order to determine the prevalence of overt and subclinical hypothyroidism, and isolated hypothyroxinemia during pregnancy, thyroid hormone reference values established by UMAE HGO4, IMSS in Mexico City and those suggested by the American Thyroid Association (ATA) were used. All pregnant patients, whose thyroid function was measured and whose pregnancy was monitored and resolved in UMAE HGO4, IMSS from 1 January to 31 December 2013, were included. Significant differences (p = .00419) were observed in the frequency of subclinical hypothyroidism, being higher when using ATA criteria (18...
October 20, 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
Seyde Shahrbanoo Daniali, Hossein Shahnazi, Samira Kazemi, Elnaz Marzbani
INTRODUCTION: Multiple Sclerosis (MS) is one of the most common autoimmune diseases affecting the central nervous system. The prevalence of it is increasing in our country too. The pain from disorders can affect quality of life. Several studies have pointed to the improvement of patients through educational intervention. This study attempted to evaluate the effectiveness of an educational intervention based on raising the awareness and self-efficacy for pain control among patients with multiple sclerosis during 2015 under the coverage of Isfahan MS Society (IMSS)...
July 24, 2016: Materia Socio-medica
Marcela Ulloa-Martínez, Ana I Burguete-García, Selvasankar Murugesan, Carlos Hoyo-Vadillo, Miguel Cruz-Lopez, Jaime García-Mena
INTRODUCTION: Obesity is a chronic, complex, and multifactorial disease, characterized by excess body fat. Diverse studies of the human genome have led to the identification of susceptibility genes that contribute to obesity. However, relatively few studies have addressed specifically the association between the level of expression of these genes and obesity. MATERIAL AND METHODS: We studied 160 healthy and obese unrelated Mexican children aged 6 to 14 years. We measured the transcriptional expression of 20 genes associated with obesity, in addition to the biochemical parameters, in peripheral white blood cells...
October 1, 2016: Archives of Medical Science: AMS
Verónica Alejandra Gaona-Flores, Luz Arcelia Campos-Navarro, Joaquín Ocampo-Martínez, Enrique Alcalá-Martínez, Margarita Patiño-Pozas
UNLABELLED: The Advance Directive is generally conceptualized as the respect that all human beings deserve in the use of their faculties, to deliberate, choose, and decide upon everything that pertains to their existence, including their life goals and personal health. OBJECTIVE: To identify knowledge about the AD that Medical Residents at tertiary care facilities of the Mexican Social Security Institute (Instituto Mexicano del Seguro Social, IMSS) in the District Capital (Mexico City), possess...
July 2016: Gaceta Médica de México
Martin Meyer, Helena Fehling, Jenny Matthiesen, Stephan Lorenzen, Kathrin Schuldt, Hannah Bernin, Mareen Zaruba, Corinna Lender, Thomas Ernst, Harald Ittrich, Thomas Roeder, Egbert Tannich, Hannelore Lotter, Iris Bruchhaus
We here compared pathogenic (p) and non-pathogenic (np) isolates of Entamoeba histolytica to identify molecules involved in the ability of this parasite to induce amoebic liver abscess (ALA)-like lesions in two rodent models for the disease. We performed a comprehensive analysis of 12 clones (A1-A12) derived from a non-pathogenic isolate HM-1:IMSS-A and 12 clones (B1-B12) derived from a pathogenic isolate HM-1:IMSS-B. "Non-pathogenicity" included the induction of small and quickly resolved lesions while "pathogenicity" comprised larger abscess development that overstayed day 7 post infection...
August 2016: PLoS Pathogens
Víctor Hugo Borja-Aburto, Javier Dávila-Torres, Ramón Alberto Rascón-Pacheco, Margot González-León, José Esteban Fernández-Gárate, Ivonne Mejía-Rodríguez, José de Jesús González-Izquierdo, Pedro Mario Escudero-de Los Ríos
UNLABELLED: Objetive: To analyze cancer mortality in affiliates of the Mexican Social Security Institute (Instituto Mexicano del Seguro Social - IMSS) and time trends in the risk of death due to cancer from 1989 to 2013. MATERIALS AND METHODS: A descriptive analysis of cancer mortality trends in beneficiaries of the IMSS was performed. Age- and sex-adjusted mortality rates were obtained using direct standardization with the WHO population. Changes in the risk of death due to cancer over time were evaluated using Poisson regression...
April 2016: Salud Pública de México
Margot González-León, José Esteban Fernández-Gárate, Ramón Alberto Rascón-Pacheco, Miguel Ángel Valladares-Aranda, Javier Dávila-Torres, Víctor Hugo Borja-Aburto
OBJECTIVE: To estimate the disease burden of cancer in the affiliate population of the Mexican Social Security Institute (Instituto Mexicano del Seguro Social, IMSS) in 2010 by delegation. MATERIALS AND METHODS: The Disability-Adjusted Life Years (DALYs), Years of Life Lost (YLL) due to premature mortality and Years Lived with Disability/Disease (YLD) for 21 specific cancers and a subgroup of other malignant neoplasms were calculated based on the methodology of the Global Burden of Disease Study (GBD) for each of the 35 delegations of the IMSS...
April 2016: Salud Pública de México
Adriana Zubieta-Zavala, Guillermo Salinas-Escudero, Adrian Ramírez-Chávez, Luis García-Valladares, Malaquias López-Cervantes, Juan Guillermo López Yescas, Luis Durán-Arenas
INTRODUCTION: The increasing burden of dengue fever (DF) in the Americas, and the current epidemic in previously unaffected countries, generate major costs for national healthcare systems. There is a need to quantify the average cost per DF case. In Mexico, few data are available on costs, despite DF being endemic in some areas. Extrapolations from studies in other countries may prove unreliable and are complicated by the two main Mexican healthcare systems (the Secretariat of Health [SS] and the Mexican Social Security Institute [IMSS])...
August 2016: PLoS Neglected Tropical Diseases
Nora Rios-Sarabia, Olivia Hernández-González, Jorge González-Y-Merchand, Guadalupe Gordillo, Guillermo Vázquez-Rosales, Leopoldo Muñoz-Pérez, Javier Torres, Carmen Maldonado-Bernal
Tuberculous meningitis (TBM) is the most severe form of tuberculosis. It is caused by Mycobacterium tuberculosis (M. tuberculosis; MT) and it is very difficult to diagnose. The symptoms are similar to other infectious neurological diseases, such as neurocysticercosis, neuroborreliosis, or herpes viral infection. The aim of this study was to identify tuberculosis (TB) in cases of meningitis with clinical and laboratory evidence suggestive of TBM, and to confirm our findings with molecular tests for TB infection...
October 2016: International Journal of Molecular Medicine
Leonardo Salas-Zapata, Lina Sofía Palacio-Mejía, Belkis Aracena-Genao, Juan Eugenio Hernández-Ávila, Emmanuel Salvador Nieto-López
OBJECTIVE: To estimate the direct costs related to hospitalizations for diabetes mellitus and its complications in the Mexican Institute of Social Security METHODS: The hospital care costs of patients with diabetes mellitus using diagnosis-related groups in the IMSS (Mexican Institute of Social Security) and the hospital discharges from the corresponding E10-E14 codes for diabetes mellitus were estimated between 2008-2013. Costs were grouped according to demographic characteristics and main condition, and were estimated in US dollars in 2013...
August 2, 2016: Gaceta Sanitaria
David G Lugo-Palacios, John Cairns, Cynthia Masetto
BACKGROUND: The prevalence of diabetes among adults in Mexico has increased markedly from 6.7 % in 1994 to 14.7 % in 2015. Although the main diabetic complications can be prevented or delayed with timely and effective primary care, a high percentage of diabetic patients have developed them imposing an important preventable burden on Mexican society and on the health system. This paper estimates the financial and health burden caused by potentially preventable hospitalisations due to diabetic complications in hospitals operated by the largest social security institution in Latin America, the Mexican Institute of Social Security (IMSS), in the period 2007-2014...
2016: BMC Health Services Research
Antonio Méndez-Durán, Manuel Humberto Ignorosa-Luna, Gilberto Pérez-Aguilar, Francisco Jesús Rivera-Rodríguez, José Jesús González-Izquierdo, Javier Dávila-Torres
BACKGROUND: The IMSS performs systematically the data updating of patients with renal replacement therapy (RRT) by an electronic record management referred as: Census patients with Chronical Renal Failure (CIRC) which aims to meet the prevalence of patients with chronic renal failure and the behavior of RRTat the IMSS. METHODS: A retrospective study includes 212 secondary hospitals with dialysis programs, with both pediatric and adult patients. CIRC data obtained from January to December 2014, number and nominal bonds of peritoneal dialysis (PD) and hemodialysis (HD)...
September 2016: Revista Médica del Instituto Mexicano del Seguro Social
Bianca Alanis-Rivera, Luis Abraham Zúñiga-Vázquez, María Carmen Silva-Escamilla
BACKGROUND: Recent studies considered hyperbilirubinemia as a marker to identify the presence of perforated appendix. The aim of the study is to verify that the presence of hyperbilirubinemia is a useful marker to identify the presence of perforated appendix before surgery, and thereby, provide early treatment to avoid progression of the disease and its complications. METHODS: This is a retrospective study, which identified 225 patients, who met the inclusion and exclusion criteria, from January 2012 to October 2014 at the IMSS General Hospital 29, taking into account laboratory results and postoperative, performing a univariate, bivariate and multivariate analysis...
September 2016: Revista Médica del Instituto Mexicano del Seguro Social
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