Victor Schweiger, Thomas Gilhofer, Rick Fang, Alessandro Candreva, Burkhardt Seifert, Davide Di Vece, Michael Wuerdinger, Iva Koleva, Katja Rajman, Maciej Cieslik, Alexander Gotschy, Jonathan Michel, Julia Stehli, David Niederseer, Linn Ryberg, Jelena Ghadri, Frank Ruschitzka, Barbara Stähli, Victoria Lucia Cammann, Christian Templin
BACKGROUND: Coronary microvascular dysfunction (CMD) has been proposed as a crucial factor in the pathophysiology of Takotsubo syndrome (TTS). The angiography-derived index of microcirculatory resistance (caIMR) offers an alternative to conventional hyperemic wire-based IMR to assess CMD. We aimed to evaluate CMD's prevalence, transience, and impact on in-hospital outcomes in TTS. METHODS: All three coronary arteries of 96 patients with TTS were assessed for their coronary angiography derived Index of microcirculatory Resistance (caIMR) and compared to non-obstructed vessels of matched patients with ST-elevation myocardial infarction...
November 20, 2023: Clinical Research in Cardiology: Official Journal of the German Cardiac Society