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https://www.readbyqxmd.com/read/28517022/impact-and-management-of-left-ventricular-function-on-the-prognosis-of-takotsubo-syndrome
#1
Ibrahim El-Battrawy, Uzair Ansari, Siegfried Lang, Michael Behnes, Katja Schramm, Christian Fastner, Xiaobo Zhou, Jürgen Kuschyk, Erol Tülümen, Susanne Röger, Martin Borggrefe, Ibrahim Akin
AIMS: Early research has proposed that patients with Takotsubo syndrome (TTS) could have a higher mortality rate than the general population. Our study was conducted to determine the short- and long-term outcome of TTS patients associated with a significantly compromised left ventricular function on hospital admission. METHODS AND RESULTS: Our institutional database constituted a collective of 112 patients diagnosed with TTS between 2003 and 2015. The patients were classified into two groups based on the left ventricular ejection fraction (LVEF), with those presenting with a LVEF >35% on admission categorized into one group (n=65, 58%) and those presenting with LVEF ≤35% (n=47, 42%) categorized into another group...
May 18, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28485570/tuning-porosity-and-surface-area-in-mesoporous-silicon-for-application-in-li-ion-battery-electrodes
#2
John B Cook, Hyung-Seok Kim, Terri Chai Lin, Shauna Robbennolt, Eric Detsi, Bruce S Dunn, Sarah H Tolbert
This work aims to improve the poor cycle lifetime of silicon based anodes for Li-ion batteries by tuning microstructural parameters such as pore size, pore volume, and specific surface area in chemically synthesized mesoporous silicon. Here we have specifically produced two different mesoporous silicon samples from the magnesiothermic reduction of ordered mesoporous silica in either argon or forming gas. In-situ X-ray diffraction studies indicate that samples made in Ar proceed through a Mg2Si intermediate, and this results in samples with larger pores (diameter ~90 nm), modest total porosity (34%), and modest specific surface area (50 m2 g-1)...
May 9, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28467231/smoking-behaviors-among-adolescents-in-foster-care-a-gender-based-analysis
#3
Svetlana Shpiegel, Steve Sussman, Scott E Sherman, Omar El Shahawy
BACKGROUND AND OBJECTIVES: Adolescents in foster care are at high risk for cigarette smoking. However, it is not clear how their smoking behaviors vary by gender. The present study examined lifetime and current smoking among males and females, and explored gender-specific risk factors for engagement in smoking behaviors. METHOD: Data from the Multi Site Evaluation of Foster Youth Programs was used to evaluate patterns of smoking among adolescents aged 12-18 years (N = 1121; 489 males, 632 females)...
May 3, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28464035/modelling-risk-adjusted-variation-in-length-of-stay-among-australian-and-new-zealand-icus
#4
Lahn D Straney, Andrew A Udy, Aidan Burrell, Christoph Bergmeir, Sue Huckson, D James Cooper, David V Pilcher
PURPOSE: Comparisons between institutions of intensive care unit (ICU) length of stay (LOS) are significantly confounded by individual patient characteristics, and currently there is a paucity of methods available to calculate risk-adjusted metrics. METHODS: We extracted de-identified data from the Australian and New Zealand Intensive Care Society (ANZICS) Adult Patient Database for admissions between January 1 2011 and December 31 2015. We used a mixed-effects log-normal regression model to predict LOS using patient and admission characteristics...
2017: PloS One
https://www.readbyqxmd.com/read/28459929/behavioral-approach-to-appropriate-antimicrobial-prescribing-in-hospitals-the-dutch-unique-method-for-antimicrobial-stewardship-dumas-participatory-intervention-study
#5
Jonne J Sikkens, Michiel A van Agtmael, Edgar J G Peters, Kamilla D Lettinga, Martijn van der Kuip, Christina M J E Vandenbroucke-Grauls, Cordula Wagner, Mark H H Kramer
Importance: Inappropriate antimicrobial prescribing leads to antimicrobial resistance and suboptimal clinical outcomes. Changing antimicrobial prescribing is a complex behavioral process that is not often taken into account in antimicrobial stewardship programs. Objective: To examine whether an antimicrobial stewardship approach grounded in behavioral theory and focusing on preserving prescriber autonomy and participation is effective in improving appropriateness of antimicrobial prescribing in hospitals...
May 1, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28387195/orthopedic-surgeons-knowledge-regarding-risk-of-radiation-exposition-a-survey-analysis
#6
Nejat Tunçer, Ersin Kuyucu, Şafak Sayar, Gökhan Polat, İrem Erdil, İbrahim Tuncay
INTRODUCTION: The purpose of this study is to evaluate the knowledge levels of orthopedic surgeons working in Turkey about the uses and possible risks of fluoroscopy and assess methods for preventing radiation damage. METHODS: A questionnaire with a total of 12 questions was sent to 1121 orthopedic surgeons working in Turkey. The questionnaire evaluated participants' knowledge about the uses and risks of fluoroscopy and methods for preventing damage. One thousand and twenty-four orthopedic surgeons were found to be suitable for inclusion in the study...
2017: SICOT-J
https://www.readbyqxmd.com/read/28367525/the-distribution-of-orbscan-indices-in-young-population
#7
Hassan Hashemi, Mehdi Khabazkhoob, Negareh Yazdani, Hadi Ostadimoghaddam, Payam Nabovati, Raheleh Moravej, AbbasAli Yekta
PURPOSE: To determine the distribution of anterior eye biometry indices, such as keratometry pachymetry, anterior chamber depth (ACD), pupil diameter, and corneal diameter, as measured by Orbscan instrument in a young Iranian population. METHODS: A cross-sectional study was conducted, and subjects were selected through multistage cluster sampling from the students of Mashhad University of Medical Sciences. Objective and subjective refraction were performed followed by Orbscan imaging...
March 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28366342/pharmacokinetics-of-rotigotine-transdermal-system-in-adolescents-with-idiopathic-restless-legs-syndrome-willis-ekbom-disease
#8
Jan-Peer Elshoff, John Hudson, Daniel L Picchietti, Keith Ridel, Arthur S Walters, Kimberly Doggett, Kimberly Moran, Marga Oortgiesen, Francisco Ramirez, Erwin Schollmayer
OBJECTIVE: To investigate the pharmacokinetics (PK) of rotigotine transdermal system in adolescents with moderate-to-severe idiopathic restless legs syndrome (RLS). METHODS: This multicenter, open-label, dose-escalation study enrolled patients ≥13 to <18 years of age. Rotigotine transdermal patches were applied daily and up-titrated weekly: 0.5, 1, 2, 3 mg/24 h. Blood samples were collected on the final day of each dose step. Primary PK variables were the apparent total body clearance (CL/f; L/h) and volume of distribution at steady state (VSS/f; L) of unconjugated rotigotine for each dose step, calculated for the PK per-protocol set (PKPPS)...
April 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28328718/validity-of-daily-and-weekly-self-reported-training-load-measures-in-adolescent-athletes
#9
Padraic J Phibbs, Gregory Roe, Ben Jones, Dale B Read, Jonathon Weakley, Joshua Darrall-Jones, Kevin Till
Phibbs, PJ, Roe, G, Jones, B, Read, DB, Weakley, J, Darrall-Jones, J, and Till, K. Validity of daily and weekly self-reported training load measures in adolescent athletes. J Strength Cond Res 31(4): 1121-1126, 2017-The primary aim of the study was to assess the level of agreement between the criterion session rating of perceived exertion (sRPE30min) and a practical measure of a self-reported Web-based training load questionnaire 24 hours after training (sRPE24h) in adolescent athletes. The secondary aim was to assess the agreement between weekly summated sRPE24h values (∑sRPE24h) and a weekly Web-based training diary (sRPEweekly) for all field-based training accumulated on a subsequent training week...
April 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28282851/twenty-four-hour-real-time-continuous-monitoring-of-cerebral-edema-in-rabbits-based-on-a-noninvasive-and-noncontact-system-of-magnetic-induction
#10
Gen Li, Ke Ma, Jian Sun, Gui Jin, Mingxin Qin, Hua Feng
Cerebral edema is a common disease, secondary to craniocerebral injury, and real-time continuous monitoring of cerebral edema is crucial for treating patients after traumatic brain injury. This work established a noninvasive and noncontact system by monitoring the magnetic induction phase shift (MIPS) which is associated with brain tissue conductivity. Sixteen rabbits (experimental group n = 10, control group, n = 6) were used to perform a 24 h MIPS and intracranial pressure (ICP) simultaneously monitored experimental study...
March 8, 2017: Sensors
https://www.readbyqxmd.com/read/28271424/a-randomized-controlled-multisite-study-of-behavioral-interventions-for-veterans-with-mental-illness-and-antipsychotic-medication-associated-obesity
#11
Zachary D Erickson, Crystal L Kwan, Hollie A Gelberg, Irina Y Arnold, Valery Chamberlin, Jennifer A Rosen, Chandresh Shah, Charles T Nguyen, Gerhard Hellemann, Dixie R Aragaki, Charles F Kunkel, Melissa M Lewis, Neena Sachinvala, Patrick A Sonza, Joseph M Pierre, Donna Ames
BACKGROUND: Weight gain and other metabolic sequelae of antipsychotic medications can lead to medication non-adherence, reduced quality of life, increased costs, and premature mortality. Of the approaches to address this, behavioral interventions are less invasive, cost less, and can result in sustained long-term benefits. OBJECTIVE: We investigated behavioral weight management interventions for veterans with mental illness across four medical centers within the Veterans Affairs (VA) Healthcare System...
April 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28195351/association-of-adipoq-leptin-lepr-and-resistin-polymorphisms-with-obesity-parameters-in-hammam-sousse-sahloul-heart-study
#12
Nesrine Zayani, Asma Omezzine, Imen Boumaiza, Ons Achour, Lamia Rebhi, Jihen Rejeb, Nabila Ben Rejeb, Ahmed Ben Abdelaziz, Ali Bouslama
BACKGROUND: Adipose tissue is an important endocrine organ that secretes a number of adipokines, such as adiponectin (ADIPOQ), leptin (LEP), leptin receptor (LEPR), and resistin (RETN) which may be implicated in obesity. Some adipokines' polymorphisms of genes might influence their concentrations and/or activities. Our aim was to study the relationship between seven SNPs in ADIPOQ (+45T<G (rs2241766); +276G<T (rs1501299); -4255C<T (rs822393); -395G<T (rs17366568)), LEP (2548G<A (rs7799039)), LEPR (223Q<R (rs1137101)), and RETN (-420C<G (rs1862513)) and obesity in Hammam Sousse Sahloul Heart Study (HSHS)...
February 13, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28185782/acute-pulmonary-embolism-detection-with-ventilation-perfusion-spect-combined-with-full-dose-ct-what-is-the-best-option
#13
M Milà, J Bechini, A Vázquez, V Vallejos, M Tenesa, A Espinal, M Fraile, M Monreal
AIM: To compare diagnostic accuracy of Ventilation/Perfusion (V/P) single-photon emission computed tomography (SPECT) combined with simultaneous full-dose CT with a hybrid SPECT/CT scanner versus planar ventilation/perfusion (V/P) SPECT and CT angiography (CTA) in patients suspected with acute pulmonary embolism (PE). METHODS: Between 2009 and 2011, consecutive patients suspected of acute PE were referred for V/P SPECT/CT (reviewed board approved study). A contrast agent was administered to patients who had no contraindications...
May 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28184228/marker-aided-incorporation-of-saltol-a-major-qtl-associated-with-seedling-stage-salt-tolerance-into-oryza-sativa-pusa-basmati-1121
#14
N Naresh Babu, S Gopala Krishnan, K K Vinod, S L Krishnamurthy, Vivek K Singh, Madan P Singh, Renu Singh, Ranjith K Ellur, Vandna Rai, Haritha Bollinedi, Prolay K Bhowmick, Ashutosh K Yadav, Mariappan Nagarajan, Nagendra K Singh, Kumble V Prabhu, Ashok K Singh
Pusa Basmati 1121 (PB1121), an elite Basmati rice cultivar is vulnerable to salinity at seedling stage. A study was undertaken to impart seedling-stage salt tolerance into PB1121 by transferring a quantitative trait locus (QTL), Saltol, using FL478 as donor, through marker assisted backcrossing. Sequence tagged microsatellite site (STMS) marker RM 3412, tightly linked to Saltol was used for foreground selection. Background recovery was estimated using 90 genome-wide STMS markers. Systematic phenotypic selection helped in accelerated recovery of recurrent parent phenome (RPP)...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28154326/marketing-approval-of-ethical-kampo-medicines
#15
Takashi Hakamatsuka
 Kampo medicine is an original traditional medicine in Japan. Currently, 148 ethical Kampo formulations (Kampo prescription drugs) are registered in the National Health Insurance Price List. Kampo medicines can be prescribed under the national insurance system, which shows that they are part of conventional medicine in Japan. Japan has a unified drug approval system that does not distinguish between Western and Kampo medicines, and both are subject to the same regulations. The application for the market approval of ethical Kampo medicines is based on the general notification for drugs, i...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28151865/differential-effects-of-stress-and-african-ancestry-on-preterm-birth-and-related-traits-among-us-born-and-immigrant-black-mothers
#16
Hui-Ju Tsai, Pamela J Surkan, Stella M Yu, Deanna Caruso, Xiumei Hong, Tami R Bartell, Anastacia D Wahl, Claire Sampankanpanich, Anne Reily, Barry S Zuckerman, Xiaobin Wang
Preterm birth (PTB, <37 weeks of gestation) is influenced by a wide range of environmental, genetic and psychosocial factors, and their interactions. However, the individual and joint effects of genetic factors and psychosocial stress on PTB have remained largely unexplored among U.S. born versus immigrant mothers.We studied 1121 African American women from the Boston Birth Cohort enrolled from 1998 to 2008. Regression-based analyses were performed to examine the individual and joint effects of genetic ancestry and stress (including lifetime stress [LS] and stress during pregnancy [PS]) on PTB and related traits among U...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28140748/the-effects-of-icariin-on-the-expression-of-hif-1%C3%AE-hsp-60-and-hsp-70-in-pc12-cells-suffered-from-oxygen-glucose-deprivation-induced-injury
#17
Zhen-Tao Mo, Wen-Na Li, Yu-Rong Zhai, Shu-Ying Gao
CONTEXT: The effects of icariin, a chief constituent of flavonoids from Epimedium brevicornum Maxim (Berberidaceae), on the levels of HIF-1α, HSP-60 and HSP-70 remain unknown. OBJECTIVE: To explore the effects of icariin on the levels of HSP-60, HIF-1α and HSP-70 neuron-specific enolase (NSE) and cell viability. MATERIALS AND METHODS: PC12 cells were treated with icariin (10(-7), 10(-6) or 10(-5 )mol/L) for 3 h (1 h before oxygen-glucose deprivation (OGD) plus 2 h OGD)...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28127202/tracing-overlapping-biological-signals-in-mid-infrared-using-colonic-tissues-as-a-model-system
#18
Ranjit Kumar Sahu, Ahmad Salman, Shaul Mordechai
AIM: To understand the interference of carbohydrates absorbance in nucleic acids signals during diagnosis of malignancy using Fourier transform infrared (FTIR) spectroscopy. METHODS: We used formalin fixed paraffin embedded colonic tissues to obtain infrared (IR) spectra in the mid IR region using a bruker II IR microscope with a facility for varying the measurement area by varying the aperture available. Following this procedure we could measure different regions of the crypt circles containing different biochemicals...
January 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28048110/su-f-j-102-lower-esophagus-margin-implications-based-on-rapid-computational-algorithm-for-sbrt
#19
M Cardenas, T Mazur, H Li, S Mutic, J Bradley, C Tsien, O Green
PURPOSE: To quantify inter-fraction esophagus-variation. METHODS: Computed tomography and daily on-treatment 0.3-T MRI data sets for 7 patients were analyzed using a novel Matlab-based (Mathworks, Natick, MA) rapid computational method. Rigid registration was performed from the cricoid to the gastro-esophageal junction. CT and MR-based contours were compared at slice intervals of 3mm. Variation was quantified by "expansion," defined as additional length in any radial direction from CT contour to MR contour...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047543/su-f-t-23-correspondence-factor-correction-coefficient-for-commissioning-of-leipzig-and-valencia-applicators-with-the-standard-imaging-ivb-1000
#20
J Donaghue, S Gajdos
PURPOSE: To determine the correction factor of the correspondence factor for the Standard Imaging IVB 1000 well chamber for commissioning of Elekta's Leipzig and Valencia skin applicators. METHODS: The Leipzig and Valencia applicators are designed to treat small skin lesions by collimating irradiation to the treatment area. Published output factors are used to calculate dose rates for clinical treatments. To validate onsite applicators, a correspondence factor (CFrev) is measured and compared to published values...
June 2016: Medical Physics
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