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https://www.readbyqxmd.com/read/28195351/association-of-adipoq-leptin-lepr-and-resistin-polymorphisms-with-obesity-parameters-in-hammam-sousse-sahloul-heart-study
#1
Nesrine Zayani, Asma Omezzine, Imen Boumaiza, Ons Achour, Lamia Rebhi, Jihen Rejeb, Nabila Ben Rejeb, Ahmed Ben Abdelaziz, Ali Bouslama
BACKGROUND: Adipose tissue is an important endocrine organ that secretes a number of adipokines, such as adiponectin (ADIPOQ), leptin (LEP), leptin receptor (LEPR), and resistin (RETN) which may be implicated in obesity. Some adipokines' polymorphisms of genes might influence their concentrations and/or activities. Our aim was to study the relationship between seven SNPs in ADIPOQ (+45T<G (rs2241766); +276G<T (rs1501299); -4255C<T (rs822393); -395G<T (rs17366568)), LEP (2548G<A (rs7799039)), LEPR (223Q<R (rs1137101)), and RETN (-420C<G (rs1862513)) and obesity in Hammam Sousse Sahloul Heart Study (HSHS)...
February 13, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28185782/acute-pulmonary-embolism-detection-with-ventilation-perfusion-spect-combined-with-full-dose-ct-what-is-the-best-option
#2
M Milà, J Bechini, A Vázquez, V Vallejos, M Tenesa, A Espinal, M Fraile, M Monreal
AIM: To compare diagnostic accuracy of Ventilation/Perfusion (V/P) single-photon emission computed tomography (SPECT) combined with simultaneous full-dose CT with a hybrid SPECT/CT scanner versus planar ventilation/perfusion (V/P) SPECT and CT angiography (CTA) in patients suspected with acute pulmonary embolism (PE). METHODS: Between 2009 and 2011, consecutive patients suspected of acute PE were referred for V/P SPECT/CT (reviewed board approved study). A contrast agent was administered to patients who had no contraindications...
February 6, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28184228/marker-aided-incorporation-of-saltol-a-major-qtl-associated-with-seedling-stage-salt-tolerance-into-oryza-sativa-pusa-basmati-1121
#3
N Naresh Babu, S Gopala Krishnan, K K Vinod, S L Krishnamurthy, Vivek K Singh, Madan P Singh, Renu Singh, Ranjith K Ellur, Vandna Rai, Haritha Bollinedi, Prolay K Bhowmick, Ashutosh K Yadav, Mariappan Nagarajan, Nagendra K Singh, Kumble V Prabhu, Ashok K Singh
Pusa Basmati 1121 (PB1121), an elite Basmati rice cultivar is vulnerable to salinity at seedling stage. A study was undertaken to impart seedling-stage salt tolerance into PB1121 by transferring a quantitative trait locus (QTL), Saltol, using FL478 as donor, through marker assisted backcrossing. Sequence tagged microsatellite site (STMS) marker RM 3412, tightly linked to Saltol was used for foreground selection. Background recovery was estimated using 90 genome-wide STMS markers. Systematic phenotypic selection helped in accelerated recovery of recurrent parent phenome (RPP)...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28154326/marketing-approval-of-ethical-kampo-medicines
#4
Takashi Hakamatsuka
 Kampo medicine is an original traditional medicine in Japan. Currently, 148 ethical Kampo formulations (Kampo prescription drugs) are registered in the National Health Insurance Price List. Kampo medicines can be prescribed under the national insurance system, which shows that they are part of conventional medicine in Japan. Japan has a unified drug approval system that does not distinguish between Western and Kampo medicines, and both are subject to the same regulations. The application for the market approval of ethical Kampo medicines is based on the general notification for drugs, i...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28151865/differential-effects-of-stress-and-african-ancestry-on-preterm-birth-and-related-traits-among-us-born-and-immigrant-black-mothers
#5
Hui-Ju Tsai, Pamela J Surkan, Stella M Yu, Deanna Caruso, Xiumei Hong, Tami R Bartell, Anastacia D Wahl, Claire Sampankanpanich, Anne Reily, Barry S Zuckerman, Xiaobin Wang
Preterm birth (PTB, <37 weeks of gestation) is influenced by a wide range of environmental, genetic and psychosocial factors, and their interactions. However, the individual and joint effects of genetic factors and psychosocial stress on PTB have remained largely unexplored among U.S. born versus immigrant mothers.We studied 1121 African American women from the Boston Birth Cohort enrolled from 1998 to 2008. Regression-based analyses were performed to examine the individual and joint effects of genetic ancestry and stress (including lifetime stress [LS] and stress during pregnancy [PS]) on PTB and related traits among U...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28140748/the-effects-of-icariin-on-the-expression-of-hif-1%C3%AE-hsp-60-and-hsp-70-in-pc12-cells-suffered-from-oxygen-glucose-deprivation-induced-injury
#6
Zhen-Tao Mo, Wen-Na Li, Yu-Rong Zhai, Shu-Ying Gao
CONTEXT: The effects of icariin, a chief constituent of flavonoids from Epimedium brevicornum Maxim (Berberidaceae), on the levels of HIF-1α, HSP-60 and HSP-70 remain unknown. OBJECTIVE: To explore the effects of icariin on the levels of HSP-60, HIF-1α and HSP-70 neuron-specific enolase (NSE) and cell viability. MATERIALS AND METHODS: PC12 cells were treated with icariin (10(-7), 10(-6) or 10(-5 )mol/L) for 3 h (1 h before oxygen-glucose deprivation (OGD) plus 2 h OGD)...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28127202/tracing-overlapping-biological-signals-in-mid-infrared-using-colonic-tissues-as-a-model-system
#7
Ranjit Kumar Sahu, Ahmad Salman, Shaul Mordechai
AIM: To understand the interference of carbohydrates absorbance in nucleic acids signals during diagnosis of malignancy using Fourier transform infrared (FTIR) spectroscopy. METHODS: We used formalin fixed paraffin embedded colonic tissues to obtain infrared (IR) spectra in the mid IR region using a bruker II IR microscope with a facility for varying the measurement area by varying the aperture available. Following this procedure we could measure different regions of the crypt circles containing different biochemicals...
January 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28048110/su-f-j-102-lower-esophagus-margin-implications-based-on-rapid-computational-algorithm-for-sbrt
#8
M Cardenas, T Mazur, H Li, S Mutic, J Bradley, C Tsien, O Green
PURPOSE: To quantify inter-fraction esophagus-variation. METHODS: Computed tomography and daily on-treatment 0.3-T MRI data sets for 7 patients were analyzed using a novel Matlab-based (Mathworks, Natick, MA) rapid computational method. Rigid registration was performed from the cricoid to the gastro-esophageal junction. CT and MR-based contours were compared at slice intervals of 3mm. Variation was quantified by "expansion," defined as additional length in any radial direction from CT contour to MR contour...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047543/su-f-t-23-correspondence-factor-correction-coefficient-for-commissioning-of-leipzig-and-valencia-applicators-with-the-standard-imaging-ivb-1000
#9
J Donaghue, S Gajdos
PURPOSE: To determine the correction factor of the correspondence factor for the Standard Imaging IVB 1000 well chamber for commissioning of Elekta's Leipzig and Valencia skin applicators. METHODS: The Leipzig and Valencia applicators are designed to treat small skin lesions by collimating irradiation to the treatment area. Published output factors are used to calculate dose rates for clinical treatments. To validate onsite applicators, a correspondence factor (CFrev) is measured and compared to published values...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28025307/five-year-safety-data-from-encore-a-european-observational-safety-registry-for-adults-with-crohn-s-disease-treated-with-infliximab-remicade%C3%A2-or-conventional-therapy
#10
Geert D'Haens, Walter Reinisch, Jean-Frederic Colombel, Julian Panes, Subrata Ghosh, Cosimo Prantera, Stefan Lindgren, Daniel W Hommes, Zhiping Huang, Judith Boice, Susan Huyck, Freddy Cornillie
BACKGROUND AND AIMS: The ENCORE registry aimed at comparing the long-term safety of Crohn's disease [CD] treatment with infliximab [Remicade(®)] and with conventional therapies in real-world clinical practice. METHODS: The 5-year, prospective, observational ENCORE registry followed patients with CD in nine European countries, who received treatment with infliximab, conventional therapies, or switched to infliximab from conventional therapy. Adverse events [AEs] in pre-specified categories and serious AEs were recorded at least every 6 months of the 5-year observation period...
December 26, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28018408/integrating-high-resolution-water-footprint-and-gis-for-promoting-water-efficiency-in-the-agricultural-sector-a-case-study-of-plantation-crops-in-the-jordan-valley
#11
Eliav Shtull-Trauring, Ido Aviani, Dror Avisar, Nirit Bernstein
Addressing the global challenges to water security requires a better understanding of humanity's use of water, especially the agricultural sector that accounts for 70% of global withdrawals. This study combined high resolution-data with a GIS system to analyze the impact of agricultural practices, crop type, and spatial factors such as drainage basins, climate, and soil type on the Water Footprint (WF) of agricultural crops. The area of the study, the northern Lower Jordan Valley, covers 1121 ha in which three main plantation crops are grown: banana (cultivated in open-fields or net-houses), avocado and palm-dates...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27899123/a-functional-magnetic-resonance-imaging-investigation-of-visual-hallucinations-in-the-human-striate-cortex
#12
Hina Abid, Fayyaz Ahmad, Soo Y Lee, Hyun W Park, Dongmi Im, Iftikhar Ahmad, Safee U Chaudhary
PURPOSE: Human beings frequently experience fear, phobia, migraine and hallucinations, however, the cerebral mechanisms underpinning these conditions remain poorly understood. Towards this goal, in this work, we aim to correlate the human ocular perceptions with visual hallucinations, and map them to their cerebral origins. METHODS: An fMRI study was performed to examine the visual cortical areas including the striate, parastriate and peristriate cortex in the occipital lobe of the human brain...
November 29, 2016: Behavioral and Brain Functions: BBF
https://www.readbyqxmd.com/read/27857219/empirically-testing-vaterite-structural-models-using-neutron-diffraction-and-thermal-analysis
#13
Bryan C Chakoumakos, Brenda M Pracheil, Ryan P Koenigs, Ronald M Bruch, Mikhail Feygenson
Otoliths, calcium carbonate (CaCO3) ear bones, are among the most commonly used age and growth structures of fishes. Most fish otoliths are comprised of the most dense CaCO3 polymorph, aragonite. Sturgeon otoliths, in contrast, have been characterized as the rare and structurally enigmatic polymorph, vaterite-a metastable polymorph of CaCO3. Vaterite is an important material ranging from biomedical to personal care applications although its crystal structure is highly debated. We characterized the structure of Lake Sturgeon otoliths using thermal analysis and neutron powder diffraction, which is used non-destructively...
November 18, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27855478/interventions-for-treating-burning-mouth-syndrome
#14
REVIEW
Roddy McMillan, Heli Forssell, John Ag Buchanan, Anne-Marie Glenny, Jo C Weldon, Joanna M Zakrzewska
BACKGROUND: Burning mouth syndrome (BMS) is a term used for oral mucosal pain (burning pain or discomfort in the tongue, lips or entire oral cavity) without identifiable cause. General population prevalence varies from 0.1% to 3.9%. Many BMS patients indicate anxiety, depression, personality disorders and impaired quality of life (QoL). This review updates the previous versions published in 2000 and 2005. OBJECTIVES: To determine the effectiveness and safety of any intervention versus placebo for symptom relief and changes in QoL, taste, and feeling of dryness in people with BMS...
18, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27850758/1121-to-prone-or-not-to-prone-the-adult-vv-ecmo-patient-is-it-safe-that-is-the-question
#15
Kate Dolly, Maria Madden, Ray Rector, Tina Wright, Amber Pyzik, Ali Tabatabai, Daniel Herr, Jay Menaker
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27834695/genome-sequences-of-malonate-positive-cronobacter-sakazakii-serogroup-o-2-sequence-type-64-strains-cdc-1121-73-and-gk1025-isolated-from-human-bronchial-wash-and-a-powdered-infant-formula-manufacturing-plant
#16
H R Chase, G R Gopinath, J Gangiredla, I R Patel, M H Kothary, L Carter, V Sathyamoorthy, B Lee, E Park, Y J Yoo, T J Chung, H Choi, S Jun, J Park, S Jeong, M Kim, F Reich, G Klein, B D Tall
We introduce draft genome sequences of strains CDC1121-73 (human bronchial wash isolate) and GK1025 (powdered infant formula manufacturing facility isolate), which are both malonate-positive Cronobacter sakazakii serogroup O:2, sequence type 64. Assemblies for these strains have sizes of 4,442,307 and 4,599,266 bp and % G+C contents of 56.9 and 56.7, respectively.
November 10, 2016: Genome Announcements
https://www.readbyqxmd.com/read/27833404/transcatheter-arterial-chemoembolization-plus-131-i-labelled-metuximab-versus-transcatheter-arterial-chemoembolization-alone-in-intermediate-advanced-stage-hepatocellular-carcinoma-a-systematic-review-and-meta-analysis
#17
Ze-Xin Zhu, Ming-Heng Liao, Xiao-Xue Wang, Ji-Wei Huang
OBJECTIVE: The aim of the study was to compare transcatheter arterial chemoembolization (TACE) plus (131)I-labelled metuximab with TACE alone for hepatocellular carcinoma (HCC). MATERIALS AND METHODS: A comprehensive search was conducted in PubMed, Embase, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and Chinese BioMedical Literature Database with published date from the earliest to February 29th, 2016. No language restrictions were applied, but only prospective randomized controlled trials (RCTs) or non-RCTs were eligible for a full-text review...
November 2016: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/27754117/os-23-04-a-novel-hormone-therapy-drospirenone-with-estradiol-for-hypertensive-postmenopausal-women-a-systemic-review-and-meta-analysis
#18
Xu Zhao, Jing Yu
OBJECTIVE: To assess the efficacy and safety of a novel hormone therapy, drospirenone combined with 17-β-estradiol (DRSP/E2) in postmenopausal hypertensive women. DESIGN AND METHOD: A systemic literature search of PubMed, Embase, Cochrane Library, Web of Science (up to Oct. 2015) was performed. Studies were screened independently by two researchers according to the inclusion and exclusion criteria which included only the randomized controlled trials (RCT) about the drospirenone with 17-β-estradiol for postmenopausal women with hypertension...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27736935/chemical-compensation-of-mitochondrial-phospholipid-depletion-in-yeast-and-animal-models-of-parkinson-s-disease
#19
Shaoxiao Wang, Siyuan Zhang, Chuan Xu, Addie Barron, Floyd Galiano, Dhaval Patel, Yong Joo Lee, Guy A Caldwell, Kim A Caldwell, Stephan N Witt
We have been investigating the role that phosphatidylethanolamine (PE) and phosphatidylcholine (PC) content plays in modulating the solubility of the Parkinson's disease protein alpha-synuclein (α-syn) using Saccharomyces cerevisiae and Caenorhabditis elegans. One enzyme that synthesizes PE is the conserved enzyme phosphatidylserine decarboxylase (Psd1/yeast; PSD-1/worms), which is lodged in the inner mitochondrial membrane. We previously found that decreasing the level of PE due to knockdown of Psd1/psd-1 affects the homeostasis of α-syn in vivo...
2016: PloS One
https://www.readbyqxmd.com/read/27722805/role-of-computed-tomography-at-a-cancer-center-emergency-department
#20
Jessyca Couto Otoni, Julia Noschang, Thábata Yaedu Okamoto, Diego Rosseman Vieira, Michel Souto Mayor Petry, Lucas de Araujo Ramos, Paula Nicole Vieira Pinto Barbosa, Almir Galvão Vieira Bitencourt, Rubens Chojniak
To evaluate the imaging methods used at the emergency department (ED) of a cancer center, with emphasis on computed tomography (CT). A descriptive, retrospective, single-center study was conducted by reviewing imaging exams and medical records, after approval of the institution's Ethics Review Board. The demographic data, cancer history, and imaging exam requested were evaluated for all patients and the indications and results of head, chest, and abdominopelvic CT scans were also evaluated. During the study period, there were 8710 visits to the ED, and 5999 imaging studies were requested in 3788 patients (43...
October 8, 2016: Emergency Radiology
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