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https://www.readbyqxmd.com/read/29450217/a-cross-sectional-assessment-of-cutaneous-lumbosacral-and-coccygeal-physical-examination-findings-in-a-healthy-newborn-population
#1
Janelle Aby, Juliann Lipps Kim
Objective. The purpose of this study is to describe the range and frequency of cutaneous lumbosacral and coccygeal findings encountered during the newborn examination in a population of apparently healthy babies, to determine if the prevalence of these findings is associated with race/ethnicity, and to report the frequency of co-occurrence of low-risk cutaneous findings. Methods . Lumbosacral physical findings of 1121 infants were documented on well newborns at least 35 weeks or greater gestational age under the authors' care...
2018: Global Pediatric Health
https://www.readbyqxmd.com/read/29409963/web-based-longitudinal-remote-assessment-of-dry-eye-symptoms
#2
Francisco Amparo, Reza Dana
PURPOSE: To investigate the feasibility of remote assessment and follow-up of dry eye symptoms using electronic versions of two validated questionnaires. METHODS: We conducted a prospective study of consecutive patients with dry eye disease (DED). Patients were enrolled during a clinical visit and were explained how to respond electronic versions of the Ocular surface Disease Index (OSDI) and the Symptom Assessment in Dry Eye (SANDE) questionnaires using a computer in the presence of investigators...
January 31, 2018: Ocular Surface
https://www.readbyqxmd.com/read/29381715/enterohemorrhagic-escherichia-coli-o157-subclade-8b-strains-in-chiba-prefecture-japan-produced-larger-amounts-of-shiga-toxin-2-than-strains-in-subclade-8a-and-other-clades
#3
Shinichiro Hirai, Eiji Yokoyama, Taku Wakui, Taichiro Ishige, Masaki Nakamura
Enterohemorrhagic Escherichia coli O157 (O157) strains can be classified into clades (one of several phylogenetic groups) by single nucleotide polymorphisms (SNPs): these are clade 1, clade 2, clade 3, descendant and ancestral clades 4/5, clade 6, clade 7, clade 8, clade 9, and clade 12. Some recent studies showed that some O157 strains in clade 8 produced a larger amount of Shiga toxin (Stx) 2 than other strains. In this study, 1121 epidemiologically unlinked strains of O157 isolated in Chiba Prefecture, Japan were classified into clades during 1996-2014...
2018: PloS One
https://www.readbyqxmd.com/read/29379327/assessment-of-the-association-between-drug-disposal-practices-and-drug-use-and-storage-behaviors
#4
Ahmet Akici, Volkan Aydin, Arzu Kiroglu
Objective: Keeping unnecessary drugs at home is a situation showing both causes and consequences of irrational use of medicine. This study aimed to evaluate the approaches of a company's employees regarding drug storage, use, and disposal. Method: This online-based descriptive study was held in a multi-centered private-sector company in a voluntary basis. The survey assessing participants' drug handling and storage behaviors was answered by 1121 employees from across eight provinces of Turkey in 2016...
January 2018: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/29356995/effect-of-qgn4-1-qtl-for-grain-number-per-panicle-in-genetic-backgrounds-of-twelve-different-mega-varieties-of-rice
#5
Vijay Kumar Singh, Ranjith Kumar Ellur, Ashok Kumar Singh, M Nagarajan, Brahma Deo Singh, Nagendra Kumar Singh
BACKGROUND: Rice is a major source of food, particularly for the growing Asian population; hence, the utilization of genes for enhancing its yield potential is important for ensuring food security. Earlier, we have mapped a major quantitative trait loci (QTL) for the grain number per panicle, qGN4.1, using biparental recombinant inbred line (RIL) populations involving a new plant type Indica rice genotype Pusa 1266. Later, three independent studies have confirmed the presence of a major QTL for spikelet number by three different names (SPIKE, GPS and LSCHL4) in the same chromosomal region, and have implicated the overexpression of Nal1 gene as the causal factor for high spikelet number...
January 22, 2018: Rice
https://www.readbyqxmd.com/read/29317400/two-year-outcomes-of-intravitreal-ziv-aflibercept
#6
Ahmad M Mansour, Mohammed Ashraf, Abdulrazzak Charbaji, Muhammad H Younis, Ahmed A Souka, Avantika Dogra, Hana A Mansour, Jay Chhablani
AIM: To assess the two-year outcome of intravitreal ziv-aflibercept (IVZ) in eyes with macular diseases. METHODS: Consecutive subjects with various macular diseases that received six or more of 0.05 mL IVZ (1.25 mg) injections with at least 1 year follow-up were included. Outcome measures were best-corrected visual acuity (BCVA) (logarithm of the minimum angle of resolution) and central macular thickness (CMT) on spectral domain optical coherence tomography...
January 9, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29298649/an-inflammation-related-nutrient-pattern-is-associated-with-both-brain-and-cognitive-measures-in-a-multiethnic-elderly-population
#7
Yian Gu, Jennifer J Manly, Richard P Mayeux, Adam M Brickman
BACKGROUND: Accumulating evidence suggest that dietary factors are associated with Alzheimer's disease, and brain and cognitive health. It is unclear whether inflammation explains this association. OBJECTIVE: To examine whether an inflammation-related nutrient pattern (INP) was associated with neuroimaging and cognitive measures of brain health. METHOD: The current cross-sectional study included 330 non-demented elderly (mean age 79 years at MRI scan) participants in a multi-ethnic, community-based cohort study who had information on nutritional intakes (estimated from food frequency questionnaire), circulating C-reactive protein and interleukin-6 (measured by ELISA), MRI scans, and cognition...
January 1, 2018: Current Alzheimer Research
https://www.readbyqxmd.com/read/29297315/utilizing-random-forest-qsar-models-with-optimized-parameters-for-target-identification-and-its-application-to-target-fishing-server
#8
Kyoungyeul Lee, Minho Lee, Dongsup Kim
BACKGROUND: The identification of target molecules is important for understanding the mechanism of "target deconvolution" in phenotypic screening and "polypharmacology" of drugs. Because conventional methods of identifying targets require time and cost, in-silico target identification has been considered an alternative solution. One of the well-known in-silico methods of identifying targets involves structure activity relationships (SARs). SARs have advantages such as low computational cost and high feasibility; however, the data dependency in the SAR approach causes imbalance of active data and ambiguity of inactive data throughout targets...
December 28, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/29232958/architect-hiv-combo-ag-ab%C3%A2-and-realtime%C3%A2-hiv-1-assays-detect-diverse-hiv-strains-in-clinical-specimens
#9
Mary A Rodgers, Ana S Vallari, Julie Yamaguchi, Vera Holzmayer, Barbara Harris, Coumba Toure-Kane, Souleymane M'Boup, Samar Badreddine, Carole McArthur, Nicaise Ndembi, Dora Ngum Mbanya, Lazare Kaptué, Gavin Cloherty
Periodic evaluation of the impact of viral diversity on diagnostic tests is critical to ensure current technologies are keeping pace with viral evolution. To determine whether HIV diversity impacts the ARCHITECT HIV Combo Ag/Ab (HIV Combo) or RealTime HIV-1 (RT) assays, a set of N=199 HIV clinical specimens from Cameroon, Senegal, Saudi Arabia, and Thailand were sequenced and tested in both assays. The panel included historical Group N and P specimens and a newly identified Group N specimen. These and specimens classified as H, U/URF, CRF01, 02, 06, 09, 11, 13, 18, 22, 37, and 43 were detected by both the RT assay (1...
December 12, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/29228708/blood-biomarkers-in-adults-with-lymph-node-enlargement-contribute-to-diagnostic-significance-of-malignancy
#10
Shanshan Ma, Junbin Guo, Danlei Lu, Lixia Zhu, Meng Zhou, De Zhou, Li Li, Jingjing Zhu, Xiudi Yang, Yanlong Zheng, Xiujin Ye, Wanzhuo Xie
Lymph node enlargement is a common presentation and has a possibility of malignancy like lymphoma that requires early diagnosis. This study aims to analyze the clinical characteristics of these patients and finds out useful predictors of malignant diseases. We retrospectively investigated 81 patients with lymph node enlargement between July 2, 2014 and May 17, 2016. The characteristics and laboratory findings were evaluated combining with the final diagnosis. The diagnoses were malignancy in 51 patients and benign lymphadenopathy in 30 patients...
November 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29217904/comparison-of-the-short-term-outcomes-of-laparoscopic-and-open-resections-for-colorectal-cancer-in-patients-with-a-history-of-prior-median-laparotomy
#11
Young Wan Kim, Ik Yong Kim
This study aimed to investigate the short-term outcomes of laparoscopic resection in comparison with those of open resection for colorectal cancer in patients with a history of prior median laparotomy (PML). Eighty-seven consecutive patients (87/1121, 7.8 %) with a history of PML who underwent major colorectal cancer resection were enrolled (laparoscopy, n = 40; open, n = 47). The conversion rate to open surgery was 25 % (n = 10). The laparoscopy group had a higher proportion of female patients (57...
December 2017: Indian Journal of Surgery
https://www.readbyqxmd.com/read/29201968/clinicopathologic-study-of-intra-osseous-lesions-of-the-jaws-in-southern-iranian-population
#12
Zohreh Jaafari-Ashkavandi, Behrooz Akbari
Statement of the Problem: It is necessary for surgeons and practitioners to know about relative incidence and clinicopathologic features of lesions for accurate diagnosis and approach of pathologic lesions. Data are limited about overall incidence of intra-osseous lesions of the jaws in Iranian patients. Purpose: This study evaluated the clinicopathologic features of intra- osseous lesions of the jaws in an Iranian population, in a 22-year period. Materials and Method: In this cross- sectional retrospective analytical study, 4500 specimens in a 22- year period were reviewed...
December 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/29112363/green-fabrication-of-ultrathin-co3o4-nanosheets-from-metal-organic-framework-for-robust-high-rate-supercapacitors
#13
Zhenyu Xiao, Lili Fan, Ben Xu, Shanqing Zhang, Wenpei Kang, Zixi Kang, Huan Lin, Xiuping Liu, Shiyu Zhang, Daofeng Sun
Two-dimensional Cobalt oxide (Co3O4) is a promising candidate for high performance and robust electrochemical capacitors. Herein, we use 2,3,5,6-tetramethyl-1,4- diisophthalate as a recyclable ligand to construct a Co-based metal-organic framework of UPC-9, and subsequently, we obtain ultrathin hierarchical Co3O4 hexagonal nanosheets with a thickness of 3.5 nm through a hydrolysis and calcination process. A remarkable and excellent specific capacitance of 1121 F∙g-1 at a current density of 1 A∙g-1 and 873 F∙g-1 at a current density of 25 A∙g-1 were achieved for the as-prepared asymmetric supercapacitor, which can be attributed to the ultrathin 2D morphology and the resultant rich macroporous and mesoporous structures of the ultrathin Co3O4 nanosheets...
November 7, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29107580/awareness-of-blood-group-and-blood-donation-among-medical-students
#14
Olga Ciepiela, Anna Jaworska, Dominika Łacheta, Natalia Falkowska, Katarzyna Popko, Urszula Demkow
BACKGROUND: Transfusion of blood-derived products is often used as a life-saving treatment, and being a blood donor should be common, especially among medical professionals. Thus, an awareness of one's own blood type in medical students should be common. Our aim was to assess if students of the Medical University of Warsaw know their blood type and how many of them are registered blood donors. MATERIAL AND METHODS: A survey was conducted in a group of 1121 students...
October 18, 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/29071392/a-transcriptome-snp-derived-linkage-map-of-apios-americana-potato-bean-provides-insights-about-genome-re-organization-and-synteny-conservation-in-the-phaseoloid-legumes
#15
Jugpreet Singh, Scott R Kalberer, Vikas Belamkar, Teshale Assefa, Matthew N Nelson, Andrew D Farmer, William J Blackmon, Steven B Cannon
We report a linkage map for Apios americana and describe synteny with selected warm-season legumes. A translocation event in common bean and soybean is confirmed against Apios and Vigna species. Apios (Apios americana; "apios"), a tuberous perennial legume in the Phaseoleae tribe, was widely used as a food by Native Americans. Work in the last 40 years has led to several improved breeding lines. Aspects of the pollination biology (complex floral structure and tripping mechanism) have made controlled crosses difficult, and the previous reports indicated that the plant is likely primarily an outcrosser...
October 25, 2017: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/29020506/potential-application-of-immobilized-streptokinase-extracted-from-streptococcus-equinus-vit_vb2
#16
B Vaishnavi, C Subathra Devi
Streptokinase purified from Streptococcus equinus VIT_VB2 isolated from bovine milk sample was immobilized in various solid supports namely entrapment in agarose gel, calcium alginate beads and gelatin gel by crosslinking with formaldehyde. Immobilization of streptokinase in calcium alginate beads showed maximum efficiency (81.8 ± 1.06%) when compared to entrapment with agarose gel (55.6 ± 2.17%) and cross-linked gelatin formaldehyde gel (71.0 ± 1.54%). The purified SK activity was expressed maximum in calcium alginate (1%) and gelatin gel (0...
October 11, 2017: Preparative Biochemistry & Biotechnology
https://www.readbyqxmd.com/read/28988641/sex-dependent-effects-of-diabetes-mellitus-on-the-revascularization-rate-in-mid-term-follow-up-of-young-patients-with-coronary-artery-disease
#17
Masoumeh Lotfi-Tokaldany, Seyed Hesameddinn Abbasi, Abbasali Karimi, Seyed Ebrahim Kassaian, Tahereh Davarpasand, Arash Jalali, Saeed Sadeghian
AIMS: We investigated the association between Type-2 diabetes mellitus (DM) and the need for revascularization at a 5-year follow-up of young coronary artery disease patients and the role of sex in this regard. METHODS: Among 1121 young (males≤45, and females≤55years) patients (female: 49.7%) from Tehran Heart Center's Premature Coronary Atherosclerosis Cohort, 371(33.1%) had diabetes prior to angiography. Revascularization was considered as either percutaneous coronary intervention or coronary artery bypass graft surgery...
December 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28985881/discontinuous-insurance-coverage-predicts-prolonged-hospital-stay-after-pediatric-adenotonsillectomy
#18
Dmitry Tumin, Adele King, Hina Walia, Joseph D Tobias, Vidya T Raman
BACKGROUND: Changes in health insurance coverage have been implicated in limiting access to care and increasing morbidity risk. The consequences of insurance discontinuity for surgical outcomes are unclear. In this study, we explored whether recent insurance discontinuity was associated with prolonged inpatient hospitalization after adenotonsillectomy in children. MATERIALS AND METHODS: We retrospectively evaluated single-center data on children aged 2-18 y undergoing adenotonsillectomy with overnight stay in 2009-2014...
October 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28939988/frozen-embryo-transfer-can-be-performed-in-the-cycle-immediately-following-the-freeze-all-cycle
#19
Kemal Ozgur, Hasan Bulut, Murat Berkkanoglu, Peter Humaidan, Kevin Coetzee
PURPOSE: In this study, we investigated whether the time interval between oocyte retrieval and frozen embryo transfer (FET) affected the live birth (LB) rates of human segmented-IVF cycles. METHOD: A total of 1338 ICSI freeze-all cycles were performed between February 2015 and January 2016, with 1121 FET cycles being retrospectively analyzed. All vitrified-warmed blastocyst transfers were performed in artificial FET cycles, using gonadotropin-releasing hormone (GnRH) agonist downregulation and oral estrogen endometrial preparation...
January 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28933612/do-virtual-reality-games-improve-mobility-skills-and-balance-measurements-in-community-dwelling-older-adults-systematic-review-and-meta-analysis
#20
Silvia Gr Neri, Jefferson R Cardoso, Lorena Cruz, Ricardo M Lima, Ricardo J de Oliveira, Maura D Iversen, Rodrigo L Carregaro
OBJECTIVE: To summarize evidence on the effectiveness of virtual reality games and conventional therapy or no-intervention for fall prevention in the elderly. DATA SOURCES: An electronic data search (last searched December 2016) was performed on 10 databases (Web of Science, EMBASE, PUBMED, CINAHL, LILACS, SPORTDiscus, Cochrane Library, Scopus, SciELO, PEDro) and retained only randomized controlled trials. REVIEW METHOD: Sample characteristics and intervention parameters were compared, focusing on clinical homogeneity of demographic characteristics, type/duration of interventions, outcomes (balance, reaction time, mobility, lower limb strength and fear of falling) and low risk of bias...
October 2017: Clinical Rehabilitation
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