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Zhixuan Liu, Jie Li, Jingwei Xiang, Shuai Cheng, Hao Wu, Na Zhang, Lixia Yuan, Wenfeng Zhang, Jia Xie, Yunhui Huang, Haixin Chang
It is a great challenge to obtain high performance cathodes with a high sulfur loading and good cycle performance due to the dissolution of intermediate lithium polysulfides in lithium-sulfur batteries. Herein, we report a novel hierarchical hybrid composed of nitrogen-doped porous graphene (NG), reduced fluorographene or graphene fluoride (RFG), and sulfur as a composite cathode in the Li-S batteries. In comparison with sulfur composites based on only either nitrogen-doped porous graphene or pure reduced fluorographene, the hierarchical hybrid of RFG, NG, and sulfur (NG-RFG/S) shows a better reversible capacity and rate capability performance due to a better confinement effect of lithium polysulfides and sulfur...
January 18, 2017: Physical Chemistry Chemical Physics: PCCP
Changsheng Yang, Qilai Zhao, Zhouming Feng, Mingying Peng, Zhongmin Yang, Shanhui Xu
A spectrally clean kHz-linewidth single-polarization single-frequency distributed Bragg reflector Yb-doped phosphate fiber (YPF) laser at 1120 nm (> 1100 nm) for the first time is demonstrated. By enhancing the reflectivity of output fiber Bragg grating and optimizing the length of YPF to implement the effective ASE suppression and single-longitudinal-mode long-wavelength lasing, a stable output power of over 62 mW is achieved from a 31-mm-long highly YPF with a linewidth of 5.7 kHz. The signal to noise ratio of > 67 dB, the polarization extinction ratio of > 25 dB, and the relative intensity noise of < -150 dB/Hz for the frequencies above 10...
December 26, 2016: Optics Express
José L Neira, Jennifer Bintz, María Arruebo, Bruno Rizzuti, Thomas Bonacci, Sonia Vega, Angel Lanas, Adrián Velázquez-Campoy, Juan L Iovanna, Olga Abián
Intrinsically disordered proteins (IDPs) are prevalent in eukaryotes, performing signaling and regulatory functions. Often associated with human diseases, they constitute drug-development targets. NUPR1 is a multifunctional IDP, over-expressed and involved in pancreatic ductal adenocarcinoma (PDAC) development. By screening 1120 FDA-approved compounds, fifteen candidates were selected, and their interactions with NUPR1 were characterized by experimental and simulation techniques. The protein remained disordered upon binding to all fifteen candidates...
January 5, 2017: Scientific Reports
Takeshi Fukuda, Yoshinori Umezawa, Shinjiro Tojo, Takenori Yonenaga, Akihiko Asahina, Hidemi Nakagawa, Kunihiko Fukuda
Purpose To determine the feasibility of dual-energy (DE) computed tomography (CT) with an iodine overlay image (IOI) for evaluation of psoriatic arthritis in the hand. Materials and Methods Approval from the institutional ethics committee and written informed consent from all patients were obtained. This prospective study included 16 patients who had psoriasis with finger joint symptoms from January 2015 to January 2016. Contrast material-enhanced (CE) DE CT and 1.5-T CE magnetic resonance (MR) imaging were performed within 1 month of each other...
December 29, 2016: Radiology
Peng Du, Mingdao Lei, Yu Liu, Shilin Yang
A specific and reliable HPLC-MS/MS method was developed and validated for the simultaneous determination of protocatechuic acid (PCA), scopolin, (-)-pinoresinol-4,4'-di-O-β-d-glucopyranoside (PDG), acanthoside D, acanthoside B and hyperin in rat plasma for the first time. The analytes were separated on a C18 column (50 × 2.1 mm, 1.8 µm) and a triple-quadrupole mass spectrometer equipped with an electrospray ionization (ESI) source was used for detection. The rat plasma sample was prepared using the protein precipitation procedure...
December 28, 2016: International Journal of Molecular Sciences
Hongbo Zhou, Yongfu Hou, Zhimin Zhu, Weixiong Xiao, Qian Xu, Lei Li, Xin Li, Wenchuan Chen
OBJECTIVES: To investigate the effect of low-intensity pulsed ultrasound (US) on peri-implant bone healing and osseointegration under osteoporotic conditions. METHODS: Seventy-two 12-week-old female Sprague Dawley rats received bilateral ovariectomies. Twelve weeks later, titanium implants were bilaterally placed in the proximal tibial metaphysis. The right tibia was exposed to low-intensity pulsed US (40 mW/cm(2) , spatial and temporal average) for 20 min/d starting the 2nd day after implantation, and the left tibia served as a control without stimulation...
April 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Minke H T Hartman, Ruben N Eppinga, Pieter J J Vlaar, Chris P H Lexis, Erik Lipsic, Joost D E Haeck, Dirk J van Veldhuisen, Iwan C C van der Horst, Pim van der Harst
BACKGROUND: Complex multimarker approaches to predict outcome after ST-elevation myocardial infarction (STEMI) have only considered a single baseline sample, while neglecting easily obtainable peak creatine kinase and creatine kinase-MB (CK-MB) values during hospitalization. METHODS: We studied 476 patients undergoing primary percutaneous coronary intervention for STEMI and cardiac magnetic resonance imaging (CMRI) at 4-6 months after STEMI. We determined the association with cardiac biomarkers (peak CK-MB, peak troponin T, N-terminal pro-brain natriuretic peptide), clinical and angiographic characteristics with infarct size, and LVEF, followed by association with mortality in 1120 STEMI patients...
December 27, 2016: Clinical Cardiology
Bitao Dong, Mingyan Li, Chunhui Xiao, Dawei Ding, Guoxin Gao, Shujiang Ding
Ultrathin cobalt ferrite nanosheets have been successfully assembled on the surface of reduced graphene oxide (rGO) via only adjusting the volume ratio of ethanol and deionized (DI) water and a post calcination treatment. The perpendicular ultrathin cobalt ferrite nanosheets supported by rGO sheets (CoFe2O4 NSs@rGO) can be obtained when the volume ratio of ethanol and DI water is 10:30. Correspondingly, the hierarchical porous films covering the total rGO sheets will be formed nanosheets. When evaluated as the electrodes for lithium ion batteries (LIBs) and supercapacitors (SCs), the resultant CoFe2O4 NSs@rGO hybrids exhibit highly enhanced electrochemical performance...
February 3, 2017: Nanotechnology
Brittany S Walter, Sharon N DeWitte
BACKGROUND: Late medieval England underwent intensive urbanisation, particularly in its largest city: London. Urban dwellers were exposed to factors such as high population density, elevated risk of infection, unsanitary living conditions and precarious food supplies. AIM: To assess whether the urban environment was more detrimental to health than the rural environment, this study compares risks of mortality and survival, as proxies for health, in medieval urban vs rural England...
January 17, 2017: Annals of Human Biology
Preethi Mani, Hao-Yu Ren, Ian J Neeland, Darren K McGuire, Colby R Ayers, Amit Khera, Anand Rohatgi
AIMS: Metabolic syndrome (MetS) increases atherosclerotic cardiovascular disease (ASCVD) risk. Low HDL cholesterol (HDL-C) is a diagnostic criterion of MetS and a major ASCVD risk factor. HDL particle concentration (HDL-P) associates with incident ASCVD independent of HDL-C, but its association with incident MetS has not been studied. We hypothesized that HDL-P would be inversely associated with incident metabolic syndrome independent of HDL-C and markers of adiposity and insulin resistance...
December 12, 2016: Diabetes & Metabolic Syndrome
Wan-Sen Yan, Ran-Ran Zhang, Yan Lan, Yong-Hui Li, Nan Sui
As a non-substance addiction, gambling disorder represents the model for studying the neurobiology of addiction without toxic consequences of chronic drug use. From a neuropsychological perspective, impulsivity is deemed as a potential construct responsible in the onset and development of drug addiction. The objective of this study was to investigate the associations between impulsivity and gambling status in young adults with varying severity of gambling. A sample of 1120 college students, equally divided into non-problem, at-risk and problem gamblers, were administered multiple measures of impulsivity including the UPPSP Impulsive Behaviors Scale (UPPSP), the Barratt Impulsiveness Scale-11 (BIS-11), and the Delay-discounting Test (DDT)...
December 15, 2016: Scientific Reports
Dong-Bin Wang, Zhong-Yi Sun, Li-Min Deng, De-Qing Zhu, Hong-Gang Xia, Peng-Zhi Zhu
BACKGROUND: The effectiveness of neoadjuvant chemoradiotherapy (NCRT) treatment for patients with esophageal carcinoma (EC) remains controversial. The aim of this study was to compare the effect of NCRT followed by surgery (NCRTS) with surgery alone (SA) for EC. METHODS: The PubMed, EMBASE, and the Cochrane Library databases were electronically searched up to August 2015 for all the published studies that investigated EC patients receiving either NCRTS or SA, and the reference lists were also manually examined for the eligible studies...
2016: Chinese Medical Journal
Jianfei Tu, Zhongzhi Jia, Xihui Ying, Dengke Zhang, Shaoqin Li, Feng Tian, Guomin Jiang
To investigate the incidence and outcome of major complication following conventional transarterial embolization/chemoembolization (TAE/TACE) therapy for hepatocellular carcinoma (HCC).From May 2010 to May 2016, all patients with major complication following conventional TAE/TACE for HCC were included. Major complication was defined as admission to a hospital for therapy, an unplanned increase in the level of care, prolonged hospitalization, permanent adverse sequelae, or death after conventional TAE/TACE therapy by Society of Interventional Radiology...
December 2016: Medicine (Baltimore)
L S Stapp, J Thomsen, H Schade, C Bock, F Melzner, H O Pörtner, G Lannig
Increased maintenance costs at cellular, and consequently organism level, are thought to be involved in shaping the sensitivity of marine calcifiers to ocean acidification (OA). Yet, knowledge of the capacity of marine calcifiers to undergo metabolic adaptation is sparse. In Kiel Fjord, blue mussels thrive despite periodically high seawater PCO2, making this population interesting for studying metabolic adaptation under OA. Consequently, we conducted a multi-generation experiment and compared physiological responses of F1 mussels from 'tolerant' and 'sensitive' families exposed to OA for 1 year...
December 5, 2016: Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
Lee P Ferguson, Tarriyo Gandiya, Christos Kaselas, Jigna Sheth, Asif Hasan, Hany Os Gabra
BACKGROUND/PURPOSE: The gastrointestinal system is prone to complications following heart surgery. We sought to determine the incidence and factors associated with gastrointestinal complication after cardiac surgery in children. METHODS: A retrospective review of patients aged <16years that underwent cardiac surgery between 2009 and 2013. Primary outcome was occurrence of gastrointestinal complication within 30days. Multivariable logistic regression was performed to identify variables related to occurrence of gastrointestinal complication...
November 14, 2016: Journal of Pediatric Surgery
D Vanham, A Spinewine, Ph Hantson, X Wittebole, D Wouters, B Sneyers
PURPOSE: To describe prevalence and patterns of potential drug-drug interactions (pDDIs) in the intensive care unit (ICU), occurrence of adverse drug events (ADEs), and agreement between different compendia and intensivists' perceptions. METHODS: A cross-sectional study. Drug profiles of all adult patients from 2 academic ICUs were screened on day 3 upon admission. We identified pDDIs using 3 compendia (Stockley's, Micromedex, and Epocrates) and documented their mechanism of action, clinical consequences, severity, level of evidence, and management...
October 4, 2016: Journal of Critical Care
Yatong An, Tyler Bell, Beiwen Li, Jing Xu, Song Zhang
Structured light system calibration often requires the usage of a calibration target with a similar size as the field of view (FOV), which brings challenges to a large-range structured light system calibration since fabricating large calibration targets is difficult and expensive. This paper presents a large-range system calibration method that does not need a large calibration target. The proposed method includes two stages: (1) accurately calibrate intrinsics (i.e., focal lengths and principle points) at a near range where both the camera and projector are out of focus, and (2) calibrate the extrinsic parameters (translation and rotation) from camera to projector with the assistance of a low-accuracy, large-range three-dimensional (3D) sensor (e...
November 20, 2016: Applied Optics
Joshua Glazer, Richard Medlin, Benjamin Bassin, Kyle Gunnerson
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
Ella Ekholm, Lars Hansen, Eva Johnsson, Nayyar Iqbal, Björn Carlsson, Hungta Chen, Boaz Hirshberg
OBJECTIVE: To determine if reduction in serum insulin with dapagliflozin plus saxagliptin or dapagliflozin add-on to metformin contributed to increased insulin clearance and to assess the effects of these treatments on β-cell function. METHODS: Patients (A1C 8.0%-12.0%) were randomized to 24-week, double-blind treatment with saxagliptin 5 mg/d plus dapagliflozin 10 mg/d (n=179), saxagliptin 5 mg/d plus placebo (n=176), or dapagliflozin 10 mg/d plus placebo (n=179) added to metformin...
November 16, 2016: Endocrine Practice
Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, Akira Nishi, Sho Muraki, Atsushi Tsuchiya, Hidehiro Umehara, Shin-Ya Watanabe, Issei Imoto, Tetsuro Ohmori
Previous studies suggest that elevated total homocysteine levels and the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism, which correlates with plasma total homocysteine levels, are risk factors for schizophrenia (SCZ). Recently, a large genome-wide association study (GWAS) of plasma total homocysteine levels in individuals of European ancestry identified many single-nucleotide polymorphisms (SNPs) (n=13,974). The primary purpose of this study was to examine the association between these plasma total homocysteine-related SNPs and SCZ in the Japanese population...
December 30, 2016: Psychiatry Research
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