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Vittorina Zagonel, Riccardo Torta, Vittorio Franciosi, Antonella Brunello, Guido Biasco, Daniela Cattaneo, Luigi Cavanna, Domenico Corsi, Gabriella Farina, Luisa Fioretto, Teresa Gamucci, Gaetano Lanzetta, Roberto Magarotto, Marco Maltoni, Cataldo Mastromauro, Barbara Melotti, Fausto Meriggi, Ida Pavese, Erico Piva, Cosimo Sacco, Giuseppe Tonini, Leonardo Trentin, Paola Ermacora, Antonella Varetto, Federica Merlin, Stefania Gori, Stefano Cascinu, Carmine Pinto
BACKGROUND: Early integration of palliative care in oncology practice ("simultaneous care", SC) has been shown to provide better care resulting in improved quality-of-life and also survival. We evaluated the opinions of Italian Association of Medical Oncology (AIOM) members. PATIENTS AND METHODS: A 37-item questionnaire was delivered to 1119 AIOM members. Main areas covered were: social, ethical, relational aspects of disease and communication, training, research, organizational and management models in SC...
2016: Journal of Cancer
Majdi Hamarshi, Madhuri Ramakrishnan, Maha Abu Kishk
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
Jeremy W Abetz, Nicholas G Adams, Biswadev Mitra
INTRODUCTION: Skin and soft tissue infections (SSTIs) are commonly treated in ED observation units (EDOUs). The management failure rate in this setting is high, as evidenced by a large proportion of patients requiring inpatient admission. This systematic review sought to quantify the management failure rate and identify risk factors associated with management failure. METHODS: Searches of six databases and grey literature were conducted with no limits on publication year or language...
October 25, 2016: Emergency Medicine Journal: EMJ
Ijms Editorial Office
The following changes have been made to the published paper[1].[...].
October 13, 2016: International Journal of Molecular Sciences
Dunja Kokotovic, Thue Bisgaard, Frederik Helgstrand
Importance: Prosthetic mesh is frequently used to reinforce the repair of abdominal wall incisional hernias. The benefits of mesh for reducing the risk of hernia recurrence or the long-term risks of mesh-related complications are not known. Objective: To investigate the risks of long-term recurrence and mesh-related complications following elective abdominal wall hernia repair in a population with complete follow-up. Design, Setting, and Participants: Registry-based nationwide cohort study including all elective incisional hernia repairs in Denmark from January 1, 2007, to December 31, 2010...
October 18, 2016: JAMA: the Journal of the American Medical Association
Laura Llull, Steffen Thiel, Sergio Amaro, Álvaro Cervera, Anna M Planas, Ángel Chamorro
Activation of the inflammatory generating complement system might play a pathogenic role in spontaneous subarachnoid hemorrhage (SAH). We studied whether plasma and cerebrospinal fluid (CSF) levels of complement proteins were associated with angiographic vasospasm and cerebral ischemic lesions after SAH. Ficolin-1 (M-ficolin), ficolin-3 (H-ficolin), mannose-binding lectin (MBL), MBL-associated serine protease 2 (MASP-2), MASP-3, and MAp44 were analyzed in plasma of 45 SAH patients at 24 h after bleeding. Additionally, ficolin-1 levels were measured in cerebrospinal fluid (CSF) samples obtained 24 h after bleeding in 19 patients with external ventricular drainage placement...
October 12, 2016: Molecular Neurobiology
Alice Giacomazzi, Maurizio Degan, Stefano Calabria, Alessandra Meneguzzi, Pietro Minuz
Platelet microparticles (PMPs) contribute to thrombogenesis but the effects of antiplatelet drugs on PMPs generation is undefined. The present study investigated the cellular events regulating PMPs shedding, testing in vitro platelet agonists and inhibitors. Platelet-rich plasma from healthy subjects was stimulated with arachidonic acid (AA), U46619, collagen type-I (10 and 1.5 μg/mL), epinephrine, ADP or TRAP-6 and pre-incubated with acetylsalicylic acid (ASA, 100 and 10 μmol/L), SQ-29,548, apyrase, PSB-0739, or eptifibatide...
2016: Frontiers in Pharmacology
C W Chan, H Iata, J Yaviong, M Kalkoa, S Yamar, G Taleo, R Isozumi, M Fukui, F Aoyama, A Pomer, K N Dancause, A Kaneko
The risk of malaria outbreak surfaced in Vanuatu after Tropical Cyclone (TC) Pam in March 2015. In June and July 2015 we conducted malariometric surveys on the islands of Tanna, Aneityum, and Erromango in Tafea Province, where malaria elimination had been targeted, to determine if malaria incidence had increased after TC Pam. No Plasmodium infection was detected by microscopy and PCR in 3009 survey participants. Only 6·3% (190/3007) of participants had fever. Spleen rates in children aged ⩽12 years from Aneityum and Tanna were low, at 3·6% (14/387) and 5·3% (27/510), respectively...
January 2017: Epidemiology and Infection
Andrew Carlson, Shannon David, Kyle Hackney, Brad Reed
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Marion Taine, Bénédicte Stengel, Anne Forhan, Sophie Carles, Jérémie Botton, Marie-Aline Charles, Barbara Heude
Physiological evidence suggests that birth weight (BW) and postnatal growth affect blood pressure (BP) level, independently or in interaction. Their respective roles are difficult to disentangle in epidemiological studies, however, especially when adjusting for final weight. We assessed the portion of the effect of BW on BP at 5 years that was not attributable to postnatal growth and investigated potential interactions between BW and postnatal growth velocity at different time points in the EDEN mother-child study...
October 2016: Hypertension
(no author information available yet)
Reports the retraction of "Demographic faultlines: A meta-analysis of the literature" by Sherry M. B. Thatcher and Pankaj C. Patel (, 2011[Nov], Vol 96[6], 1119-1139). At the request of the editor and in consultation with the American Psychological Association, the article is being retracted. This action is a result of a review by the editor and two additional experts that determined that there are significant errors in Tables 1, 2, and 3 which may affect the overall conclusions of the article. Co-author Pankaj C...
August 2016: Journal of Applied Psychology
Lucie Cluver, Franziska Meinck, Yulia Shenderovich, Catherine L Ward, Rocio Herrero Romero, Alice Redfern, Carl Lombard, Jenny Doubt, Janina Steinert, Ricardo Catanho, Camille Wittesaele, Sachin De Stone, Nasteha Salah, Phelisa Mpimpilashe, Jamie Lachman, Heidi Loening, Frances Gardner, Daphnee Blanc, Mzuvekile Nocuza, Meryn Lechowicz
BACKGROUND: An estimated one billion children experience child abuse each year, with the highest rates in low- and middle-income countries. The Sinovuyo Teen programme is part of Parenting for Lifelong Health, a WHO/UNICEF initiative to develop and test violence-prevention programmes for implementation in low-resource contexts. The objectives of this parenting support programme are to prevent the abuse of adolescents, improve parenting and reduce adolescent behavioural problems. This trial aims to evaluate the effectiveness of Sinovuyo Teen compared to an attention-control group of a water hygiene programme...
2016: Trials
Xavier Rod, Benoit Peyronnet, Thomas Seisen, Benjamin Pradere, Florie Gomez, Grégory Verhoest, Christophe Vaessen, Alexandre De La Taille, Karim Bensalah, Morgan Roupret
OBJECTIVE: To assess the impact of ischemia on renal function after partial nephrectomy. MATERIALS AND METHODS: A literature review was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria. In January 2015, the Medline and Embase databases were systematically searched using the protocol ("warm ischemia"[mesh] OR "warm ischemia"[ti]) AND ("nephrectomy"[mesh] OR "partial nephrectomy"[ti]). An updated search was performed in December 2015...
July 13, 2016: BJU International
Ana Ruigómez, Alexander Michel, Mar Martín-Pérez, Luis A García Rodríguez
BACKGROUND: Few studies have evaluated incidence rates and risk factors for heart failure hospitalization (HFH) and mortality starting at initial heart failure (HF) diagnosis. METHODS: Patients with a first ever recorded diagnosis of HF between January 2000 and December 2005 (N=3516) were identified from The Health Improvement Network primary care database and followed until April 2011 to identify HFHs (through linked hospitalization data) and deaths. HF patients were stratified by hospitalization status at HF diagnosis (start date), and hazard ratios (HRs) for HFH and death were estimated using Cox regression...
October 1, 2016: International Journal of Cardiology
Erika Frischknecht Christensen, Thomas Mulvad Larsen, Flemming Bøgh Jensen, Mette Dahl Bendtsen, Poul Anders Hansen, Søren Paaske Johnsen, Christian Fynbo Christiansen
OBJECTIVE: Knowledge about patients after calling for an ambulance is limited to subgroups, such as patients with cardiac arrest, myocardial infarction, trauma and stroke, while population-based studies including all diagnoses are few. We examined the diagnostic pattern and mortality among all patients brought to hospital by ambulance after emergency calls. DESIGN: Registry-based cohort study. SETTING AND PARTICIPANTS: We included patients brought to hospital in an ambulance dispatched after emergency calls during 2007-2014 in the North Denmark Region (580 000 inhabitants)...
2016: BMJ Open
Yun Ma, Shuai Tian, Shuya He, Qiong Chen, Zongbao Wang, Xiao Xiao, Liang Fu, Xiaoyong Lei
No abstract text is available yet for this article.
June 19, 2016: Gene
Peter Johnson, Massimo Federico, Amy Kirkwood, Alexander Fosså, Leanne Berkahn, Angelo Carella, Francesco d'Amore, Gunilla Enblad, Antonella Franceschetto, Michael Fulham, Stefano Luminari, Michael O'Doherty, Pip Patrick, Thomas Roberts, Gamal Sidra, Lindsey Stevens, Paul Smith, Judith Trotman, Zaid Viney, John Radford, Sally Barrington
BACKGROUND: We tested interim positron-emission tomography-computed tomography (PET-CT) as a measure of early response to chemotherapy in order to guide treatment for patients with advanced Hodgkin's lymphoma. METHODS: Patients with newly diagnosed advanced classic Hodgkin's lymphoma underwent a baseline PET-CT scan, received two cycles of ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) chemotherapy, and then underwent an interim PET-CT scan. Images were centrally reviewed with the use of a 5-point scale for PET findings...
June 23, 2016: New England Journal of Medicine
Shanshan Du, Cheng Wang, Wei Jiang, Chunlong Li, Yanchuan Li, Rennan Feng, Changhao Sun
AIM: Body weight gain adds risk for metabolic disorders and there are different metabolic changes in earlier and later adulthood. However, its impact on non-alcoholic fatty liver disease (NAFLD) was indeterminate. The aim of current study was to evaluate the impact of body weight gain on NAFLD and metabolic syndrome (MetS) during overall, earlier (25-40y) and later (over 40y) adulthood. METHODS: 1119 subjects were selected to calculate changes in body weight (ΔBW), body mass index (BMI) (ΔBMI) and bodyweight per year (ΔBW/y) to analysis their impact on NAFLD and MetS in multi-variable regression models, and explored the potential mediators that associated ΔBMI with NAFLD by mediation analysis...
December 0: Diabetes Research and Clinical Practice
Xiaoping Li, Rong Luo, Wei Fang, Xiaolei Xu, Guodong Niu, Yixian Xu, Michael Fu, Wei Hua, Xiushan Wu
BACKGROUND: Ventricular conduction blocks (VCBs) are associated with poor outcomes in patients with known cardiac diseases. However, the prognostic implications of VCB patterns in dilated cardiomyopathy (DCM) patients need to be evaluated. The purpose of this study was to determine all-cause mortality in patients with DCM and VCB. METHODS: This cohort study included 1119 DCM patients with a median follow-up of 34.3 (19.5-60.8) months, patients were then divided into left bundle branch block (LBBB), right bundle branch block (RBBB), intraventricular conduction delays (IVCD) and narrow QRS groups...
2016: BMC Cardiovascular Disorders
Chiachen Chen, Yuan-Ching Chang, Michael S Lan, Mary Breslin
Following the publication of this article, an interested reader drew to our attention an anomaly associated with the presentation of Figs. 5 and 8; essentially, the β-actin control bands in Fig. 8 appeared to be a mirror image of the same control bands shown in Fig. 5A. After having re‑examined the data, Fig. 5 was correctly presented as shown in the paper, although the β-actin blot in Fig. 8 had been inadvertently misplaced as a mirror image of the control data from Fig. 5. Two similar experiments were performed at that time, yielding similar results, and the error with the control data did not affect the second of the experiments...
August 2016: International Journal of Oncology
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