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https://www.readbyqxmd.com/read/27906722/location-and-grade-of-prostate-cancer-diagnosed-by-transperineal-template-guided-mapping-biopsy-after-negative-transrectal-ultrasound-guided-biopsy
#1
Nathan Bittner, Gregory Merrick, Al Taira, Abbey Bennett, Amy Schattel, Wayne Butler, Robert Galbreath, Edward Adamovich
OBJECTIVES: To determine the location and grade of prostate cancer diagnosed by transperineal template-guided mapping (TTMB) after negative transrectal ultrasound-guided (TRUS) biopsy. MATERIALS AND METHODS: This analysis consisted of 1118 consecutive patients who underwent TTMB from January 2005 to August 2015. Eight hundred thirty-five underwent TTMB after at least 1 negative TRUS biopsy and 283 underwent TTMB as the first biopsy procedure. The study population was divided into cohorts based on the number of prior TRUS biopsy sessions (0, 1, 2, and ≥3)...
November 30, 2016: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27850755/1118-anesthesiology-intensivist-led-perioperative-surgical-home-a-quality-assurance-pilot
#2
Khaldoun Faris, Stephen Heard, Christine Motzkus-Feagans, Masilo Grant, Jennifer Yates, Mitchell Sokoloff, Shubjeet Kaur, Theofilos Matheos
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27826592/current-knowledge-of-burn-injury-first-aid-practices-and-applied-traditional-remedies-a-nationwide-survey
#3
Abdullah E Kattan, Feras AlShomer, Abdulaziz K Alhujayri, Abdullah Addar, Albaraa Aljerian
BACKGROUND: Burn first aid awareness has been shown to reduce morbidity and mortality. We present a report on the knowledge and practices of the Saudi population with regard to burn first aid and the application of traditional remedies. METHODS: An internet-based survey was conducted to assess the public's knowledge on first aid practices and home remedies applied for burn injuries among Saudi adults. RESULTS: A total of 2758 individuals responded to the survey...
2016: Burns and trauma
https://www.readbyqxmd.com/read/27807647/epigenetic-transcriptional-memory
#4
REVIEW
Agustina D'Urso, Jason H Brickner
Organisms alter gene expression to adapt to changes in environmental conditions such as temperature, nutrients, inflammatory signals, and stress (Gialitakis et al. in Mol Cell Biol 30:2046-2056, 2010; Conrath in Trends Plant Sci 16:524-531, 2011; Avramova in Plant J 83:149-159, 2015; Solé et al. in Curr Genet 61:299-308, 2015; Ho and Gasch in Curr Genet 61:503-511, 2015; Bevington et al. in EMBO J 35:515-535, 2016; Hilker et al. in Biol Rev Camb Philos Soc 91:1118-1133, 2016). In some cases, organisms can "remember" a previous environmental condition and adapt to that condition more rapidly in the future (Gems and Partridge 2008)...
November 2, 2016: Current Genetics
https://www.readbyqxmd.com/read/27791224/impact-of-protein-nutritional-status-on-plasma-bnp-in-elderly-patients
#5
S F Chen, Y J Li, H M Song, P Wu, X S Zhang, C L Cui
BACKGROUND: Previous studies have demonstrated that the levels of B-type natriuretic peptide (BNP) in plasma are negatively correlated with Body Mass Index (BMI) whereas lean body mass is also closely related to plasma BNP. The purpose of this study is to determine the effect of protein nutritional status on plasma BNP in aged patients. METHODS AND RESULTS: The cross-sectional study was applied and the anthropometric measurement and nutritional biochemical test was performed in 1118 elderly inpatients in a stable condition were enrolled in the study (mean age, 75 years; 54% women)...
2016: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/27780795/economic-evaluation-of-text-messaging-and-smartphone-based-interventions-to-improve-medication-adherence-in-adolescents-with-chronic-health-conditions-a-systematic-review
#6
Sherif M Badawy, Lisa M Kuhns
BACKGROUND: The rate of chronic health conditions (CHCs) in children and adolescents has doubled in the past 20 years, with increased health care costs. Technology-based interventions have demonstrated efficacy to improving medication adherence. However, data to support the cost effectiveness of these interventions are lacking. OBJECTIVE: The objective of this study is to conduct an economic evaluation of text-messaging and smartphone-based interventions that focus on improving medication adherence in adolescents with CHCs...
October 25, 2016: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/27756532/association-of-metabolic-syndrome-with-erosive-esophagitis-and-barrett-s-esophagus-in-a-chinese-population
#7
Shou-Wu Lee, Han-Chung Lien, Chi-Sen Chang, Teng-Yu Lee, Yen-Chun Peng, Hong-Zen Yeh
BACKGROUND: Metabolic syndrome has been highlighted as a risk factor for several gastrointestinal diseases, including gastroesophageal reflux disease and Barrett's esophagus (BE). The aim of this study was to investigate the association of metabolic syndrome with erosive esophagitis (EE) and BE. METHODS: Data were retrospectively collected from patients who visited the Medical Screening Center at Taichung Veterans General Hospital, Taichung, Taiwan from January 2006 to December 2009...
October 15, 2016: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/27756040/predictors-of-response-to-cardiac-resynchronization-therapy-a-systematic-review
#8
John Rickard, Henry Michtalik, Ritu Sharma, Zackary Berger, Emmanuel Iyoha, Ariel R Green, Nowreen Haq, Karen A Robinson
BACKGROUND: Multiple studies have sought to determine variables associated with improved "response" to cardiac resynchronization therapy(CRT). Such variables, however, are often derived from inadequately controlled, single center cohort studies calling external validity into question. We sought to determine predictors of response to CRT-D and CRT-P utilizing the methods of systematic review. METHODS: We searched MEDLINE, Embase®, and the Cochrane Central Register of Controlled Trials (CENTRAL) from January 1, 1995, as this is the date of first article reporting use of CRT through October 20, 2014...
September 25, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27748802/-corrigendum-weighted-gene-co-expression-network-analysis-of-colorectal-cancer-liver-metastasis-genome-sequencing-data-and-screening-of-anti-metastasis-drugs
#9
Bo Gao, Qin Shao, Hani Choudhry, Victoria Marcus, Kung Dong, Jiannis Ragoussis, Zu-Hua Gao
After the publication of the article, the authors noted that the affiliation for Dr Hani Choudhry is wrong. The correct affiliation should be as follows: Bo Gao1, Qin Shao2, Hani Choudhry3, Victoria Marcus2, Kung Dong5, Jiannis Ragoussis4 and Zu-Hua Gao2, 1Department of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China; 2Department of Pathology, The Research Institute of McGill University Health Center, Montreal, Québec H4A 3J1, Canada; 3Department of Biochemistry, Faculty of Science, Cancer and Mutagenesis Unit, King Fahd Center for Medical Research, Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia; 4McGill University and Genome Quebec Innovation Centre, Montreal, Québec H3B 1S6, Canada; 5Department of Pathology, Beijing Youan Hospital, Capital Medical University, Beijing 100069, P...
October 6, 2016: International Journal of Oncology
https://www.readbyqxmd.com/read/27714996/flexible-micro-supercapacitors-using-silk-and-cotton-substrates
#10
Chayanika Das, Kothandam Krishnamoorthy
Flexible micro-supercapacitors are needed to power ultra-small wearable electronic devices. Silk cocoons comprise microfibers of silk, which are an attractive natural resource to fabricate micro-supercapacitors (MSCs). These fibers are insulators, hence, they must be converted to conducting surfaces. Polyphenols from green tea have been used as a protective layer that also acted as a reducing agent to silver ion. The reduction of silver ion resulted in the formation of silver nanoparticles that subsequently reduced gold ions to gold...
October 7, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27698100/cracking-the-code-of-resistance-across-multiple-lines-of-alk-inhibitor-therapy-in-lung-cancer
#11
Huan Qiao, Christine M Lovly
In the setting of recent exciting clinical results and numerous ongoing trials, Gainor and colleagues explored mechanisms of acquired resistance to first- and second-generation ALK inhibitors in ALK-rearranged non-small cell lung cancer and found that an increased frequency and distinct spectrums of resistance mutations emerged with the more potent second-generation inhibitors. Their findings have important and immediate clinical implications as the resistance mutations detected impart differential sensitivities to available ALK inhibitors, thereby highlighting the need for sequential biopsies with molecular testing to determine the most effective treatment strategy upon disease progression...
October 2016: Cancer Discovery
https://www.readbyqxmd.com/read/27696504/green-tea-polyphenols-require-the-mitochondrial-iron-transporter-mitoferrin-for-lifespan-extension-in-drosophila-melanogaster
#12
Terry E Lopez, Hoang M Pham, Benjamin V Nguyen, Yerazik Tahmasian, Shannon Ramsden, Volkan Coskun, Samuel E Schriner, Mahtab Jafari
Green tea has been found to increase the lifespan of various experimental animal models including the fruit fly, Drosophila melanogaster. High in polyphenolic content, green tea has been shown to reduce oxidative stress in part by its ability to bind free iron, a micronutrient that is both essential for and toxic to all living organisms. Due to green tea's iron-binding properties, we questioned whether green tea acts to increase the lifespan of the fruit fly by modulating iron regulators, specifically, mitoferrin, a mitochondrial iron transporter, and transferrin, found in the hemolymph of flies...
December 2016: Archives of Insect Biochemistry and Physiology
https://www.readbyqxmd.com/read/27668972/antenatal-glucocorticoids-and-neonatal-inflammation-associated-proteins
#13
Maheer Faden, Mari Holm, Elizabeth Allred, Raina Fichorova, Olaf Dammann, Alan Leviton
BACKGROUND: To date, studies of the relationship between antenatal glucocorticoids (AGC) and neonatal inflammation in preterm newborns have been largely limited to umbilical cord blood specimens. AIM: To explore the association between exposure to antenatal glucocorticoids and concentrations of inflammation-related proteins in whole blood collected from very preterm newborns at multiple times during the first postnatal month. METHODS: We measured the protein concentrations on postnatal day 1 (N=1118), day 7 (N=1138), day 14 (N=1030), day 21 (N=936) and day 28 (N=877) from infants born before the 28th week of gestation and explored the relationship between antenatal steroid receipt and protein concentrations in the highest and lowest quartiles...
December 2016: Cytokine
https://www.readbyqxmd.com/read/27639932/new-rickettsia-species-in-soft-ticks-ornithodoros-hasei-collected-from-bats-in-french-guiana
#14
Djamel Tahir, Cristina Socolovschi, Jean-Lou Marié, Gautier Ganay, Jean-Michel Berenger, Jean-Michel Bompar, Denis Blanchet, Marie Cheuret, Oleg Mediannikov, Didier Raoult, Bernard Davoust, Philippe Parola
In French Guiana, located on the northeastern coast of South America, bats of different species are very numerous. The infection of bats and their ticks with zoonotic bacteria, especially Rickettsia species, is so far unknown. In order to improve knowledge of these zoonotic pathogens in this French overseas department, the presence and diversity of tick-borne bacteria was investigated with molecular tools in bat ticks. In the beginning of 2013, 32 bats were caught in Saint-Jean-du-Maroni, an area close to the coast of French Guiana, and the ticks of these animals were collected...
October 2016: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/27615013/is-the-use-of-renin-angiotensin-system-inhibitors-in-patients-with-aortic-valve-stenosis-safe-and-of-prognostic-benefit-a-systematic-review-and-meta-analysis
#15
Charlotte Andersson, Jawdat Abdulla
BACKGROUND AND AIMS: Aortic valve stenosis (AVS) is associated with significant morbidity and mortality, especially in the presence of symptoms and echocardiographic signs of left ventricular remodeling (i.e., increase in left ventricular mass, left ventricular dilation, and systolic dysfunction). Renin-angiotensin system inhibitors (RASi) attenuate cardiac remodeling in various conditions, but the safety and efficacy of RASi in AVS is unsure. We performed a systematic review and meta-analysis to address these issues...
September 11, 2016: European Heart Journal. Cardiovascular Pharmacotherapy
https://www.readbyqxmd.com/read/27596838/diagnostic-performance-of-confocal-laser-endomicroscopy-for-optical-diagnosis-of-gastric-intestinal-metaplasia-a-meta-analysis
#16
Xing-Kang He, Dan Liu, Lei-Min Sun
BACKGROUND: Gastric intestinal metaplasia (IM) is generally considered as a precancerous condition, a related risk factor for intestinal-type gastric cancer. However, an accurate endoscopic diagnosis of IM is a clinical challenge. Confocal Laser Endomicroscopy (CLE) is a newly technique that can provide real-time magnified images and visualize tissues at cellular or subcellular levels. The aim of this study is to clarify the diagnostic value of CLE in detection of IM in patients at high risk of gastric cancer...
2016: BMC Gastroenterology
https://www.readbyqxmd.com/read/27594979/novel-cell-ess-%C3%A2-supplement-used-as-a-feed-or-as-an-initial-boost-to-cho-serum-free-media-results-in-a-significant-increase-in-protein-yield-and-production
#17
Adam Elhofy
Many metrics, including metabolic profiles, have been used to analyze cell health and optimize productivity. In this study, we investigated the ability of a lipid supplement to increase protein yield. At a concentration of 1% (v/v) the lipid supplement caused a significant increase in protein titer (1118 ± 65.4 ng 10(5) cells(- 1) days(- 1)) when compared to cultures grown in the absence of supplementation (819.3 ± 38.1 ng 10(5) cells(- 1) days(- 1); p < 0.05). This equated to a 37% increase in productivity...
2016: Computational and Structural Biotechnology Journal
https://www.readbyqxmd.com/read/27593214/kinetically-controlled-assembly-of-nitrogen-doped-invaginated-carbon-nanospheres-with-tunable-mesopores
#18
Yang Liu, Hongwei Zhang, Owen Noonan, Chun Xu, Yuting Niu, Yannan Yang, Liang Zhou, Xiaodan Huang, Chengzhong Yu
Mesoporous hollow carbon nanospheres (MHCS) have been extensively studied owning to their unique structural features and diverse potential applications. A surfactant-free self-assembly approach between resorcinol/formaldehyde and silicon alkoxide has emerged as an important strategy to prepare MHCS. Extending such a strategy to other substituted phenols to produce heterogeneous-atom-doped MHCS remains a challenge due to the very different polymerization kinetics of various resins. Herein, we report an ethylenediamine-assisted strategy to control the cooperative self-assembly between a 3-aminophenol/formaldehyde resin and silica templates...
October 10, 2016: Chemistry: a European Journal
https://www.readbyqxmd.com/read/27584274/correlates-of-awareness-and-use-of-a-bike-share-program-and-association-with-weight-status-1118-board-1-june-1-3-15-pm-5-15-pm
#19
Lawrence H Stahley, Sarah M Camhi, Julie A Wright, Philip J Troped
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27582888/safety-and-efficacy-of-vonoprazan-based-triple-therapy-against-helicobacter-pylori-infection-a-single-center-experience-with-1118-patients
#20
Daisuke Fukuda, Yuko Akazawa, Fuminao Takeshima, Kazuhiko Nakao, Yutaka Fukuda
No abstract text is available yet for this article.
September 2016: Therapeutic Advances in Gastroenterology
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