Read by QxMD icon Read


Bo Gao, Qin Shao, Hani Choudhry, Victoria Marcus, Kung Dong, Jiannis Ragoussis, Zu-Hua Gao
After the publication of the article, the authors noted that the affiliation for Dr Hani Choudhry is wrong. The correct affiliation should be as follows: Bo Gao1, Qin Shao2, Hani Choudhry3, Victoria Marcus2, Kung Dong5, Jiannis Ragoussis4 and Zu-Hua Gao2, 1Department of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China; 2Department of Pathology, The Research Institute of McGill University Health Center, Montreal, Québec H4A 3J1, Canada; 3Department of Biochemistry, Faculty of Science, Cancer and Mutagenesis Unit, King Fahd Center for Medical Research, Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia; 4McGill University and Genome Quebec Innovation Centre, Montreal, Québec H3B 1S6, Canada; 5Department of Pathology, Beijing Youan Hospital, Capital Medical University, Beijing 100069, P...
October 6, 2016: International Journal of Oncology
Chayanika Das, Kothandam Krishnamoorthy
Flexible micro-supercapacitors are needed to power ultra-small wearable electronic devices. Silk cocoons comprise microfibers of silk, which are an attractive natural resource to fabricate micro-supercapacitors (MSCs). These fibers are insulators, hence, they must be converted to conducting surfaces. Polyphenols from green tea have been used as a protective layer that also acted as a reducing agent to silver ion. The reduction of silver ion resulted in the formation of silver nanoparticles that subsequently reduced gold ions to gold...
October 7, 2016: ACS Applied Materials & Interfaces
Huan Qiao, Christine M Lovly
In the setting of recent exciting clinical results and numerous ongoing trials, Gainor and colleagues explored mechanisms of acquired resistance to first- and second-generation ALK inhibitors in ALK-rearranged non-small cell lung cancer and found that an increased frequency and distinct spectrums of resistance mutations emerged with the more potent second-generation inhibitors. Their findings have important and immediate clinical implications as the resistance mutations detected impart differential sensitivities to available ALK inhibitors, thereby highlighting the need for sequential biopsies with molecular testing to determine the most effective treatment strategy upon disease progression...
October 2016: Cancer Discovery
Terry E Lopez, Hoang M Pham, Benjamin V Nguyen, Yerazik Tahmasian, Shannon Ramsden, Volkan Coskun, Samuel E Schriner, Mahtab Jafari
Green tea has been found to increase the lifespan of various experimental animal models including the fruit fly, Drosophila melanogaster. High in polyphenolic content, green tea has been shown to reduce oxidative stress in part by its ability to bind free iron, a micronutrient that is both essential for and toxic to all living organisms. Due to green tea's iron-binding properties, we questioned whether green tea acts to increase the lifespan of the fruit fly by modulating iron regulators, specifically, mitoferrin, a mitochondrial iron transporter, and transferrin, found in the hemolymph of flies...
October 3, 2016: Archives of Insect Biochemistry and Physiology
Maheer Faden, Mari Holm, Elizabeth Allred, Raina Fichorova, Olaf Dammann, Alan Leviton
BACKGROUND: To date, studies of the relationship between antenatal glucocorticoids (AGC) and neonatal inflammation in preterm newborns have been largely limited to umbilical cord blood specimens. AIM: To explore the association between exposure to antenatal glucocorticoids and concentrations of inflammation-related proteins in whole blood collected from very preterm newborns at multiple times during the first postnatal month. METHODS: We measured the protein concentrations on postnatal day 1 (N=1118), day 7 (N=1138), day 14 (N=1030), day 21 (N=936) and day 28 (N=877) from infants born before the 28th week of gestation and explored the relationship between antenatal steroid receipt and protein concentrations in the highest and lowest quartiles...
December 2016: Cytokine
Djamel Tahir, Cristina Socolovschi, Jean-Lou Marié, Gautier Ganay, Jean-Michel Berenger, Jean-Michel Bompar, Denis Blanchet, Marie Cheuret, Oleg Mediannikov, Didier Raoult, Bernard Davoust, Philippe Parola
In French Guiana, located on the northeastern coast of South America, bats of different species are very numerous. The infection of bats and their ticks with zoonotic bacteria, especially Rickettsia species, is so far unknown. In order to improve knowledge of these zoonotic pathogens in this French overseas department, the presence and diversity of tick-borne bacteria was investigated with molecular tools in bat ticks. In the beginning of 2013, 32 bats were caught in Saint-Jean-du-Maroni, an area close to the coast of French Guiana, and the ticks of these animals were collected...
October 2016: Ticks and Tick-borne Diseases
Charlotte Andersson, Jawdat Abdulla
BACKGROUND AND AIMS: Aortic valve stenosis (AVS) is associated with significant morbidity and mortality, especially in the presence of symptoms and echocardiographic signs of left ventricular remodeling (i.e., increase in left ventricular mass, left ventricular dilation, and systolic dysfunction). Renin-angiotensin system inhibitors (RASi) attenuate cardiac remodeling in various conditions, but the safety and efficacy of RASi in AVS is unsure. We performed a systematic review and meta-analysis to address these issues...
September 11, 2016: European Heart Journal. Cardiovascular Pharmacotherapy
Xing-Kang He, Dan Liu, Lei-Min Sun
BACKGROUND: Gastric intestinal metaplasia (IM) is generally considered as a precancerous condition, a related risk factor for intestinal-type gastric cancer. However, an accurate endoscopic diagnosis of IM is a clinical challenge. Confocal Laser Endomicroscopy (CLE) is a newly technique that can provide real-time magnified images and visualize tissues at cellular or subcellular levels. The aim of this study is to clarify the diagnostic value of CLE in detection of IM in patients at high risk of gastric cancer...
2016: BMC Gastroenterology
Adam Elhofy
Many metrics, including metabolic profiles, have been used to analyze cell health and optimize productivity. In this study, we investigated the ability of a lipid supplement to increase protein yield. At a concentration of 1% (v/v) the lipid supplement caused a significant increase in protein titer (1118 ± 65.4 ng 10(5) cells(- 1) days(- 1)) when compared to cultures grown in the absence of supplementation (819.3 ± 38.1 ng 10(5) cells(- 1) days(- 1); p < 0.05). This equated to a 37% increase in productivity...
2016: Computational and Structural Biotechnology Journal
Yang Liu, Hongwei Zhang, Owen Noonan, Chun Xu, Yuting Niu, Yannan Yang, Liang Zhou, Xiaodan Huang, Chengzhong Yu
Mesoporous hollow carbon nanospheres (MHCS) have been extensively studied owning to their unique structural features and diverse potential applications. A surfactant-free self-assembly approach between resorcinol/formaldehyde and silicon alkoxide has emerged as an important strategy to prepare MHCS. Extending such a strategy to other substituted phenols to produce heterogeneous-atom-doped MHCS remains a challenge due to the very different polymerization kinetics of various resins. Herein, we report an ethylenediamine-assisted strategy to control the cooperative self-assembly between a 3-aminophenol/formaldehyde resin and silica templates...
October 10, 2016: Chemistry: a European Journal
Lawrence H Stahley, Sarah M Camhi, Julie A Wright, Philip J Troped
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Daisuke Fukuda, Yuko Akazawa, Fuminao Takeshima, Kazuhiko Nakao, Yutaka Fukuda
No abstract text is available yet for this article.
September 2016: Therapeutic Advances in Gastroenterology
Alexandre Hardy, Antoine Gerometta, Benjamin Granger, Audrey Massein, Laurent Casabianca, Hugues Pascal-Moussellard, Philippe Loriaut
PURPOSE: The Latarjet procedure has shown its efficiency for the treatment of anterior shoulder dislocation. The success of this technique depends on the correct positioning and fusion of the bone block. The length of the screws that fix the bone block can be a problem. They can increase the risk of non-union if too short or be the cause of nerve lesion or soft tissue discomfort if too long. Suprascapular nerve injuries have been reported during shoulder stabilisation surgery up to 6 % of the case...
August 25, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Ellen Sauar Norli, Gina H Brinkmann, Tore K Kvien, Olav Bjørneboe, Anne J Haugen, Halvor Nygaard, Cathrine Thunem, Elisabeth Lie, Maria D Mjaavatten
OBJECTIVES: To study occurrence of and factors associated with self-limiting arthritis among patients fulfilling the 2010 ACR/EULAR classification criteria for rheumatoid arthritis (RA) (2010 RA criteria) in patients with ≤16 weeks׳ duration of joint swelling. METHODS: We applied the 2010 RA criteria in 1118 patients included in a 2-year longitudinal cohort. In all, 256 patients fulfilled the 2010 RA criteria at baseline; outcome was defined as either "self-limiting arthritis" (no DMARD use during follow-up, no swollen joints at last assessment, and no final clinical diagnosis of RA) or "persistent disease...
July 20, 2016: Seminars in Arthritis and Rheumatism
Lawrence F Eichenfield, Ted Lain, Ellen H Frankel, Terry M Jones, Joan-En Chang-Lin, David R Berk, Shiling Ruan, Alexandre Kaoukhov
BACKGROUND: Dapsone gel, 5% is administered twice daily for the treatment of acne vulgaris, and some patients may find adherence challenging.<BR /> OBJECTIVE: The study objective was to assess the efficacy and safety, compared with vehicle, of acne treatment with a recently FDA-approved, once-daily formulation of dapsone gel, 7.5%, with a 50% greater concentration of dapsone.<BR /> METHODS: This 12-week, randomized, double-blind, vehicle-controlled, multicenter clinical trial enrolled patients aged 12 years and older with 20-50 facial inflammatory lesions, 30-100 facial noninflammatory lesions, and an acne grade of 3 (moderate) on the Global Acne Assessment Score (GAAS)...
August 1, 2016: Journal of Drugs in Dermatology: JDD
M R Blake, J M Raker, K Whelan
BACKGROUND: The Bristol Stool Form Scale (BSFS) is a 7-point scale used extensively in clinical practice and research for stool form measurement, which has undergone limited validity and reliability testing. AIM: To determine the validity and reliability of the BSFS in measuring stool form in healthy adults and patients with diarrhoea-predominant irritable bowel syndrome (IBS-D). METHODS: One hundred and sixty-nine healthy volunteers provided a stool sample and used the BSFS to classify stool form, which was compared with measured stool water content and with values from 19 patients with IBS-D...
October 2016: Alimentary Pharmacology & Therapeutics
Björn Stessel, Audrey A A Fiddelers, Marco A Marcus, Sander M J van Kuijk, Elbert A Joosten, Madelon L Peters, Wolfgang F F A Buhre, Hans-Fritz Gramke
OBJECTIVES: In 2009, Gramke et al have described predictive factors to pre-operatively detect those at risk for moderate to severe acute postoperative pain (APSP) after day surgery. The aim of the present study is to externally validate this initial model and to improve and internally validate a modified version of this model. METHODS: Elective patients scheduled for day surgery were prospectively enrolled from November 2008 to April 2010. Model discrimination was quantified using the area under the receiver operating characteristic curve (AUC)...
July 15, 2016: Clinical Journal of Pain
Dileepa Senajith Ediriweera, Anuradhani Kasturiratne, Arunasalam Pathmeswaran, Nipul Kithsiri Gunawardena, Buddhika Asiri Wijayawickrama, Shaluka Francis Jayamanne, Geoffrey Kennedy Isbister, Andrew Dawson, Emanuele Giorgi, Peter John Diggle, David Griffith Lalloo, Hithanadura Janaka de Silva
BACKGROUND: There is a paucity of robust epidemiological data on snakebite, and data available from hospitals and localized or time-limited surveys have major limitations. No study has investigated the incidence of snakebite across a whole country. We undertook a community-based national survey and model based geostatistics to determine incidence, envenoming, mortality and geographical pattern of snakebite in Sri Lanka. METHODOLOGY/PRINCIPAL FINDINGS: The survey was designed to sample a population distributed equally among the nine provinces of the country...
July 2016: PLoS Neglected Tropical Diseases
Ilaria Benucci, Katia Liburdi, Martina Cerreti, Marco Esti
The preparation of yeast starter culture (Pied de Cuve) for producing sparkling wine with the traditional method is a key factor for manufacturing a good Prise de mousse. In this paper, the evolution of total yeast population, its viability during Pied de Cuve preparation, and the pressure profile during the 2nd fermentation in 2 different base wines made from Bombino bianco and Chardonnay grapes were investigated using 4 different commercial active dried yeasts. The study proves that despite the initial differences observed throughout the acclimatization phase, all the tested strains showed similar results on either the total population (from 8...
August 2016: Journal of Food Science
Milada Zemanová, Tereza Stašková, Dalibor Kodrík
The role of adipokinetic hormone (AKH) and adenosine in the anti-stress response was studied in Drosophila melanogaster larvae and adults carrying a mutation in the Akh gene (Akh(1)), the adenosine receptor gene (AdoR(1)), or in both of these genes (Akh(1) AdoR(1) double mutant). Stress was induced by starvation or by the addition of an oxidative stressor paraquat (PQ) to food. Mortality tests revealed that the Akh(1) mutant was the most resistant to starvation, while the AdoR(1) mutant was the most sensitive...
August 2016: Journal of Insect Physiology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"