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https://www.readbyqxmd.com/read/29673730/early-oocyte-denudation-does-not-compromise-icsi-cycle-outcome-a-large-retrospective-cohort-study
#1
Osama Naji, Natalie Moska, Yaser Dajani, Awatuf El-Shirif, Hassan El-Ashkar, Mohamed Hosni, Mohamed Khalil, Yacoub Khalaf, Virginia Bolton, Tarek El-Toukhy
This retrospective cohort study of 2051 consecutive fresh non-donor intracytoplasmic sperm injection (ICSI) cycles investigated whether time from oocyte retrieval to denudation, precisely measured and recorded by an operator-independent automated radiofrequency-based system, affected cycle outcome. ICSI cycles were divided into two groups: group I (denudation within <2 h of oocyte retrieval, n = 1118) and group II (denudation 2-5 h after oocyte retrieval, n = 933). Univariate analysis by two-sample t-test or Mann-Whitney test was used, as appropriate...
April 4, 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29666541/antiglycation-and-antioxidant-activities-of-mogroside-extract-from-siraitia-grosvenorii-swingle-fruits
#2
Hesheng Liu, Chengcheng Wang, Xiangyang Qi, Jian Zou, Zhida Sun
Siraitia grosvenorii (Swingle) is one kind of medical and edible plants with various health-promoting properties. Recently, its hypoglycemic and antidiabetic activities have been reported, but the underlying mechanism remains to be explored. The current study was aimed to investigate the antioxidant and antiglycation activities of mogroside extract (MGE) from Siraitia grosvenorii (Swingle). The results showed that compared to glycated BSA, MGE at middle (125 μg/mL) and high dose (500 μg/mL) significantly inhibited BSA glycation evidenced by decreased fluorescent AGEs formation, protein carbonyls and Nε -(carboxymethyl) lysine (CML) level at 500 μg/mL by 58...
May 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29626996/molecular-and-biological-characterization-of-sclerotinia-sclerotiorum-resistant-to-the-anilinopyrimidine-fungicide-cyprodinil
#3
Yi-Ping Hou, Xue-Wei Mao, Xiang-Pu Qu, Jian-Xin Wang, Chang-Jun Chen, Ming-Guo Zhou
Cyprodinil belongs to the chemical class of anilinopyrimidines fungicides. In this study, baseline sensitivity of Sclerotinia sclerotiorum (Lib.) de Bary to cyprodinil was determined using 100 strains collected from the fields in Jiangsu Province of China. The EC50 (50% effective concentration) values ranged from 0.0636-0.8163 μg/ml with a mean value of 0.1869 (±0.1118) ug/ml for mycelial growth. Nine cyprodinil-resistant mutants (Range of resistance factor: 20.22-271.59) were obtained from sensitive strains exposed on PDA medium amended with cyprodinil and the resistance was stable after their ten transfers on PDA without the fungicide or stored at 4 °C for two months...
April 2018: Pesticide Biochemistry and Physiology
https://www.readbyqxmd.com/read/29611094/past-care-predicts-future-care-in-out-of-care-people-living-with-hiv-results-of-a-clinic-based-retention-in-care-intervention-in-north-carolina
#4
Jenna Donovan, Kristen Sullivan, Aimee Wilkin, Nada Fadul, Amy Heine, Jennifer Keller, Anna LeViere, Evelyn Byrd Quinlivan
Poor retention in care is associated with higher viral load (VL) results and decreased rates of viral load suppression (VS) in people living with HIV (PLWH). Therefore, improving retention in HIV care is a priority of national significance. The NC-LINK Retention Project utilized a systematic approach to identify, locate, and attempt to return to care patients who did not attend a clinic appointment for 6-9 months. Clinical and surveillance data were used to evaluate associations between patient characteristics and VL outcomes...
April 2, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29567605/sodium-dodecyl-sulfate-intercalated-and-acrylamide-anchored-layered-double-hydroxides-a-multifunctional-adsorbent-for-highly-efficient-removal-of-congo-red
#5
Lin Deng, Hanxuan Zeng, Zhou Shi, Wen Zhang, Jinming Luo
In this study, a novel adsorbent was designed and synthesized via intercalation of sodium dodecyl sulfate (SDS) in the interlayer, and subsequent grafting of acrylamide (AM) on the layer of layered double hydroxides (LDH) (named as AM/SDS-LDH), and applied for congo red (CR) removal. The morphological structure, wettability and physicochemical properties of the adsorbents were thoroughly characterized using SEM, EDS, N2 -adsorption/desorption isotherm, static contact angle, XRD and FTIR. Results elucidated that SDS and AM were successfully introduced into the interlayer and onto the layer of LDH, respectively...
March 14, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29567240/production-of-antioxidant-and-ace-inhibitory-peptides-from-kluyveromyces-marxianus-protein-hydrolysates-purification-and-molecular-docking
#6
Mahta Mirzaei, Saeed Mirdamadi, Mohamad Reza Ehsani, Mahmoud Aminlari
Kluyveromyces marxianus protein hydrolysates were prepared by two different sonicated-enzymatic (trypsin and chymotrypsin) hydrolysis treatments to obtain antioxidant and ACE-inhibitory peptides. Trypsin and chymotrypsin hydrolysates obtained by 5 h, exhibited the highest antioxidant and ACE-inhibitory activities. After fractionation using ultrafiltration and reverse phase high performance liquid chromatography (RP-HPLC) techniques, two new peptides were identified. One fragment (LL-9, MW = 1180 Da) with the amino acid sequence of Leu-Pro-Glu-Ser-Val-His-Leu-Asp-Lys showed significant ACE inhibitory activity (IC50  = 22...
April 2018: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/29552934/postconcussive-symptoms-after-single-and-repeated-concussions-in-10-to-20-year-olds-a-cross-sectional-study
#7
Temitayo Oyefunmike Oyegbile, Bronson Elizabeth Delasobera, Nassim Zecavati
The objective was to characterize cognitive deficits and postconcussive symptoms in a pediatric population with no concussion, a single concussion, and ≥2 concussions, using a cross-sectional design. Cognitive function and postconcussive symptoms were assessed in participants (age 10-20) with no concussion (n = 1118), single concussion (n = 368), and repeated (≥2) concussions (n = 252). Analyses were adjusted for age and gender. Individuals with ≥2 concussions exhibited more total postconcussive symptoms; more loss of consciousness, amnesia and confusion; more headaches; and poorer cognitive function compared to no concussion and single concussion...
January 1, 2018: Journal of Child Neurology
https://www.readbyqxmd.com/read/29499734/comparison-of-two-fda-approved-interspinous-spacers-for-treatment-of-lumbar-spinal-stenosis-superion-versus-x-stop-a-meta-analysis-from-five-randomized-controlled-trial-studies
#8
He Zhao, Li-Jun Duan, Yu-Shan Gao, Yong-Dong Yang, Ding-Yan Zhao, Xiang-Sheng Tang, Zhen-Guo Hu, Chuan-Hong Li, Si-Xue Chen, Tao Liu, Xing Yu
BACKGROUND: Decompressive laminectomy (DI) is a standard operation for lumbar spinal stenosis (LSS) patient with severe claudication symptoms for many years. However, patients whose symptom severity does not meet undergoing invasive surgery make therapeutic options into dilemma. Interspinous spacers (ISP) bridge the gap between surgical interventions and CC in management of LSS. In our study, we aim to systematically assess the two FDA-approved interspinous spacers for treatment of lumbar spinal stenosis: Superion versus X-STOP...
March 2, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29454066/walking-behavior-in-a-circular-arena-modified-by-pulsed-light-stimulation-in-drosophila-melanogaster-w-1118-line
#9
Shuang Qiu, Chengfeng Xiao
The Drosophila melanogaster white-eyed w 1118 line serves as a parental stock, allowing genetic recombination of any gene of interest along with a readily recognizable marker. w 1118 flies display behavioral susceptibility to environmental stimulation such as light. It is of great importance to characterize the behavioral performance of w 1118 flies because this would provide a baseline from which the effect of the gene of interest could be differentiated. Little work has been performed to characterize the walking behavior in adult w 1118 flies...
February 14, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29402974/genetic-variability-affects-absolute-and-relative-potencies-and-kinetics-of-the-anesthetics-isoflurane-and-sevoflurane-in-drosophila-melanogaster
#10
Zachariah P G Olufs, Carin A Loewen, Barry Ganetzky, David A Wassarman, Misha Perouansky
Genetic variability affects the response to numerous xenobiotics but its role in the clinically-observed irregular responses to general anesthetics remains uncertain. To investigate the pharmacogenetics of volatile general anesthetics (VGAs), we developed a Serial Anesthesia Array apparatus to expose multiple Drosophila melanogaster samples to VGAs and behavioral assays to determine pharmacokinetic and pharmacodynamic properties of VGAs. We studied the VGAs isoflurane and sevoflurane in four wild type strains from the Drosophila Genetic Reference Panel, two commonly used laboratory strains (Canton S and w 1118 ), and a mutant in Complex I of the mitochondrial electron transport chain (ND23 60114 )...
February 5, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29401091/pathoanatomy-of-the-tongue-type-calcaneus-fracture-assessment-using-2-and-3-dimensional-computed-tomography
#11
Phillip M Mitchell, David E O'Neill, Bethany Gallagher, Cory A Collinge
OBJECTIVE: To define the pathoanatomy of the tongue type calcaneus fracture and assess the appropriateness of percutaneous techniques in addressing all planes of deformity in this injury. DESIGN: Retrospective cohort. SETTING: ACS Level I trauma center. PATIENTS/PARTICIPANTS: Fifty-six displaced Sanders 2B and 2C tongue type calcaneus fractures identified from an initial cohort of 1118 calcaneus fractures treated over a 16-year period...
January 26, 2018: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29373265/susceptibility-of-clostridium-species-isolated-in-japan-to-fidaxomicin-and-its-major-metabolite-op-1118
#12
Katsunori Yanagihara, Norihiko Akamatsu, Junichi Matsuda, Norihito Kaku, Kiyomitsu Katsumata, Kosuke Kosai
The narrow-spectrum macrocyclic antibiotic fidaxomicin is approved for treatment of Clostridium difficile infection in many countries and is currently under evaluation in Japan for this indication. This study was conducted to evaluate the effects of fidaxomicin and its major metabolite, OP-1118, on Clostridium spp. isolated in Nagasaki University Hospital, Japan. Isolates were cultured and antimicrobial susceptibility analyses performed according to the Clinical Laboratory Standards Institute methods. Ninety-eight isolates were obtained between 2012 and 2015, 50 of C...
January 17, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29362959/single-item-measures-for-detecting-sleep-problems-in-united-states-military-veterans
#13
Jaime M Hughes, Christi S Ulmer, Jennifer M Gierisch, Matthew O Howard
BACKGROUND: As many as two-thirds of post-9/11 military veterans complain of sleep problems, including insomnia-like symptoms. Left untreated, chronic sleep problems increase the risk for a range of negative outcomes, including incident mental health disorders. However, sleep problems remain overlooked in primary care settings. To date, no brief sleep screeners have been developed or validated. Items assessing insomnia and poor sleep are often embedded into commonly used psychological assessments, and may serve as a viable first step in screening...
January 23, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29358412/pillars-article-efficient-presentation-of-soluble-antigen-by-cultured-human-dendritic-cells-is-maintained-by-granulocyte-macrophage-colony-stimulating-factor-plus-interleukin-4-and-downregulated-by-tumor-necrosis-factor-%C3%AE-j-exp-med-1994-179-1109-1118
#14
Federica Sallusto, Antonio Lanzavecchia
No abstract text is available yet for this article.
February 1, 2018: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/29322858/epidemiology-of-mental-health-conditions-in-incoming-division-i-collegiate-athletes
#15
Nikolas Sarac, Benjamin Sarac, Angela Pedroza, James Borchers
OBJECTIVES: The purpose of this study is to examine the epidemiology of mental health conditions in incoming American Division I collegiate athletes. METHODS: Pre-participation physical questionnaires from 1118 incoming student athletes at a Division I Institution were collected retrospectively from 2011-2017. Data collected included lifetime history of any mental health condition, musculoskeletal injuries, concussions, and post-concussion depression. History of any mental health condition was evaluated by gender and sport played...
January 20, 2018: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/29304943/using-a-discrete-choice-experiment-involving-cost-to-value-a-classification-system-measuring-the-quality-of-life-impact-of-self-management-for-diabetes
#16
Donna Rowen, Katherine Stevens, Alexander Labeit, Jackie Elliott, Brendan Mulhern, Jill Carlton, Hasan Basarir, Julie Ratcliffe, John Brazier
OBJECTIVES: To describe the use of a novel approach in health valuation of a discrete-choice experiment (DCE) including a cost attribute to value a recently developed classification system for measuring the quality-of-life impact (both health and treatment experience) of self-management for diabetes. METHODS: A large online survey was conducted using DCE with cost on UK respondents from the general population (n = 1497) and individuals with diabetes (n = 405). The data were modeled using a conditional logit model with robust standard errors...
January 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/29238243/analysis-of-time-motion-and-heart-rate-in-elite-male-and-female-beach-handball
#17
Basilio Pueo, Jose M Jimenez-Olmedo, Alfonso Penichet-Tomas, Manuel Ortega Becerra, Jose J Espina Agullo
Beach handball is a spectacular new team sport; however, scientific knowledge about the demands in beach handball is very low. Consequently, the aim of this study was to analyze the physical demands of elite beach handball players by means of time-motion analysis with GPS technology and physiological response with Heart Rate (HR). Both male (n = 12) and female (n = 12) players from the Spanish Beach Handball National Team were recruited for this study. The sample consisted in four matches of two 10-min periods each...
December 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/29218255/oncology-section-edge-task-force-on-urogenital-cancer-a-systematic-review-of-clinical-measures-for-incontinence
#18
Alicia Jeffrey, Shana E Harrington, Alexandra Hill, Amanda Roscow, Meryl Alappattu
Background: Compared to the general population, women and men with urogenital and colorectal cancer experience higher rates of urinary and fecal incontinence. Although a variety of measures exist to assess these areas, currently, there are no guidelines recommending which outcomes rehabilitation professionals should administer to examine these impairments in those with cancer. Purpose: To identify outcome measures for assessing urinary and fecal incontinence and evaluate their psychometric data and applicability to the cancer population...
July 2017: Rehabilitation Oncology
https://www.readbyqxmd.com/read/29167926/angiopoietin-like-protein-8-in-early-pregnancy-improves-the-prediction-of-gestational-diabetes
#19
Yun Huang, Xin Chen, Xiaohong Chen, Yu Feng, Heming Guo, Sicheng Li, Ting Dai, Rong Jiang, Xiaoyan Zhang, Chen Fang, Ji Hu
AIMS/HYPOTHESIS: Screening high-risk individuals for gestational diabetes mellitus (GDM) in early pregnancy conventionally relies on established maternal risk factors; however, the sensitivity and specificity of these factors are not satisfactory. The present study aimed to determine whether the concentration of angiopoietin-like protein 8 (ANGPTL8), either alone or combined with other risk factors in early pregnancy, could be used to predict subsequent GDM. METHODS: From August 2015 to January 2016, 474 women receiving prenatal care at around 12-16 weeks of gestation were recruited into the study...
November 22, 2017: Diabetologia
https://www.readbyqxmd.com/read/29152127/minocycline-treatment-increases-resistance-to-oxidative-stress-and-extends-lifespan-in-drosophila-via-foxo
#20
Gang Jun Lee, Jin Ju Lim, Seogang Hyun
Minocycline is a semi-synthetic tetracycline derivative antibiotic that has received increasing attention for its non-antibiotic properties, mainly anti-inflammatory, tumor-suppressive, and neuroprotective effects. Drosophila is a widely used genetically tractable model organism for studying organismal aging by virtue of its short lifespan and ease of cultivation. In this study, we examined the effects of minocycline on Drosophila lifespan and its associated traits. Minocycline-supplemented food significantly extended lifespan in both Canton S and w1118 Drosophila strains...
October 20, 2017: Oncotarget
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