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https://www.readbyqxmd.com/read/29337577/preparation-of-nano-au-pt-alloy-microspheres-decorated-with-reduced-graphene-oxide-for-non-enzymatic-hydrogen-peroxide-sensing
#1
Zhixue Bai, Wenhao Dong, Yipeng Ren, Cong Zhang, Qiang Chen
The flourish of nanotechnology has brought new vitality to the research and development of electrochemical sensing materials. In this work, we successfully synthesized Nano Au & Pt alloy microspheres decorated with reduced graphene oxide (RGO/nAPAMSs) by a simple, facile and eco-friendly one-step reduction strategy for the fabrication of highly sensitive non-enzymatic H2O2 sensing interfaces. Energy-dispersive X-ray spectroscopy mapping (EDX mapping), energy-dispersive X-ray spectroscopy analyzer (EDX), transmission electron microscopy (TEM), Fourier transform infrared spectrum (FT-IR) and X-ray diffraction spectrum (XRD) were employed to characterize RGO/nAPAMSs from a microscopic perspective...
January 16, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29315480/iris-pigmented-lesions-as-a-marker-of-cutaneous-melanoma-risk-an-australian-case-control-study
#2
A M Laino, E G Berry, K Jagirdar, K J Lee, D L Duffy, H P Soyer, R A Sturm
BACKGROUND: Iris naevi and iris freckles have a frequency of 4% and 50% in the European population. They are associated with dysplastic naevi, but few studies examine their link to cutaneous melanoma. OBJECTIVES: To assess whether iris pigmented lesions are a predictive indicator for cutaneous melanoma. METHODS: This is a melanoma case-control study of 1254 European-background Australians. Sun exposure and melanoma history, a saliva sample for DNA analysis, and eye photographs taken with a digital camera were collected from 1117 participants...
January 8, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29287752/do-orthopaedic-resident-and-fellow-case-logs-accurately-reflect-surgical-case-volume
#3
Kanu Okike, Peter Z Berger, Carrie Schoonover, Robert V O Toole
OBJECTIVE: The purpose of this study is to determine whether orthopedic resident and fellow case logs accurately reflect trainee case volume. DESIGN: For each orthopedic case performed at our institution between 7/1/14 and 10/31/14, the names of trainees who participated were obtained from the chart. The trainee Accreditation Council for Graduate Medical Education case logs were queried to determine if the procedure in question was logged and, if so, which current procedural terminology (CPT) codes were reported...
December 26, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/29280041/threshold-analysis-in-the-presence-of-both-the%C3%A2-diagnostic-and%C3%A2-the-therapeutic-risk
#4
Stefan Felder, Thomas Mayrhofer
The well-established a priori probability of illness threshold in medical decision making, introduced by Pauker and Kassirer (N Engl J Med 293:229-234, 1975; N Engl J Med 302:1109-1117, 1980), involves the diagnostic risk only. We generalize the threshold analysis by adding the therapeutic risk, i.e., in accounting for the risk that a treatment might sometimes fail. We derive a priori probability of illness threshold as a function of the probability of successful treatment, as well as the inverted function, where the successful treatment probability threshold is a function of the a priori probability of illness...
December 26, 2017: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/29279201/replication-in-imaging-genetics-the-case-of-threat-related-amygdala-reactivity
#5
Reut Avinun, Adam Nevo, Annchen R Knodt, Maxwell L Elliott, Ahmad R Hariri
BACKGROUND: Low replication rates are a concern in most, if not all, scientific disciplines. In psychiatric genetics specifically, targeting intermediate brain phenotypes, which are more closely associated with putative genetic effects, was touted as a strategy leading to increased power and replicability. In the current study, we attempted to replicate previously published associations between single nucleotide polymorphisms and threat-related amygdala reactivity, which represents a robust brain phenotype not only implicated in the pathophysiology of multiple disorders, but also used as a biomarker of future risk...
November 16, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/29276590/correlation-of-gastroesophageal-reflux-disease-assessment-symptom-questionnaire-to-impedance-ph-measurements-in-children
#6
Sittichoke Prachuapthunyachart, Chaowapong Jarasvaraparn, David A Gremse
Background: Esophageal multichannel intraluminal impedance-pH monitoring has become one of the preferred tests to correlate observed reflux-like behaviors with esophageal reflux events. The Gastroesophageal reflux disease Assessment Symptom Questionnaire is a validated tool used to distinguish infants with gastroesophageal reflux disease from healthy children. The aim of this study was to determine whether the Gastroesophageal reflux disease Assessment Symptom Questionnaire composite symptom scores and individual symptom scores correlate with outcomes in esophageal multichannel intraluminal impedance-pH monitoring...
2017: SAGE Open Medicine
https://www.readbyqxmd.com/read/29261401/prevalence-of-and-comorbid-health-conditions-associated-with-pediatric-prescription-opioid-use-in-the-us
#7
Souvik Banerjee, Carl L Roland, Richard Willke, Jack Mardekian, Louis P Garrison
Prescription opioids are among the most effective analgesics to treat moderate to severe pain; however, little is known about the use of prescription opioids in children, particularly those receiving an extended-release formulation for the treatment of chronic pain. In this retrospective study, the authors determined the prevalence of prescription opioid use among 7-17-year-old children and associated comorbid health conditions from 2010 to 2013 using Truven Health MarketScan (MarketScan) and Optum Clinformatics DataMart (Optum)...
December 20, 2017: Journal of Pain & Palliative Care Pharmacotherapy
https://www.readbyqxmd.com/read/29198658/immunologic-long-term-outcomes-of-living-related-kidney-transplantations-depending-on-the-donor-recipient-relationship
#8
D Khadzhynov, F Halleck, L Lehner, D Schmidt, E Schrezenmeier, K Budde, O Staeck
BACKGROUND: The aim of this study is to analyze the long-term immunologic outcomes of living-related kidney transplantations depending on the donor-recipient relationship. METHODS: This retrospective single-center study included adult kidney transplant recipients (KTR) transplanted between 2000 and 2014. Among 1117 KTRs, 178 patients (15.9%) received living-related donations. Those patients were further categorized according to the donor-recipient relationship: 65 transplantations between siblings, 39 father-to-child (F-t-C) and 74 mother-to-child (M-t-C) donations...
December 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/29198046/is-treatment-of-geriatric-hip-fracture-patients-cost-covering-results-of-a-prospective-study-conducted-at-a-german-university-hospital
#9
Rene Aigner, Juliana Hack, Daphne Eschbach, Steffen Ruchholtz, Matthias Knobe, Richard Dodel, Benjamin Buecking
INTRODUCTION: Hip fractures have increased medical and socio-economic importance due to demographic transition. Information concerning direct treatment costs and their reimbursement in Germany is lacking. MATERIALS AND METHODS: Four hundred two hip fracture patients older than 60 years of age were observed prospectively at a German University Hospital. Treatment costs were determined with up to 196 cost factors and compared to the reimbursement. Finally, statistical analysis was performed to identify clinical parameters influencing the cost-reimbursement relation...
December 2, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29193136/clinical-indications-for-intravenous-immunoglobulin-utilization-in-a-tertiary-medical-center-a-9-year-retrospective-study
#10
Asaf Shemer, Shaye Kivity, Yehuda Shoenfeld
BACKGROUND: Intravenous immunoglobulins (IVIG) are a biologic product originally developed to treat immunocompromised patients. In the past decades, there has been increased utilization of IVIG in autoimmune conditions. The objectives were to evaluate the clinical use of IVIG in the largest tertiary medical center in Israel and to determine top uses, estimate off-label usage, and assess consumption of this blood product. STUDY DESIGN AND METHODS: We conducted an observational, retrospective study involving all patients who received IVIG from 2007 through 2015...
November 27, 2017: Transfusion
https://www.readbyqxmd.com/read/29175060/evaluation-of-the-contribution-of-d9s1120-to-anthropological-studies-in-native-american-populations
#11
J A Aguilar-Velázquez, V Manuel Martínez-Sevilla, M Sosa-Macías, A González-Martin, J F Muñoz-Valle, H Rangel-Villalobos
The D9S1120 locus exhibits a population-specific allele of 9 repeats (9RA) in all Native American and two Siberian populations currently studied, but it is absent in other worldwide populations. Although this feature has been used in anthropological genetic studies, its impact on the evaluation of the structure and genetic relations among Native American populations has been scarcely assessed. Consequently, the aim of this study was to evaluate the anthropological impact of D9S1120 when it was added to STR population datasets in Mexican Native American groups...
October 26, 2017: Homo: Internationale Zeitschrift Für die Vergleichende Forschung Am Menschen
https://www.readbyqxmd.com/read/29159458/cardiopulmonary-exercise-testing-reflects-improved-exercise-capacity-in-response-to-treatment-in-morquio-a-patients-results-of-a-52-week-pilot-study-of-two-different-doses-of-elosulfase-alfa
#12
Kenneth I Berger, Barbara K Burton, Gregory D Lewis, Mark Tarnopolsky, Paul R Harmatz, John J Mitchell, Nicole Muschol, Simon A Jones, V Reid Sutton, Gregory M Pastores, Heather Lau, Rebecca Sparkes, Adam J Shaywitz
OBJECTIVE: To assess impact of a 52-week elosulfase alfa enzyme replacement therapy (ERT) on exercise capacity in Morquio A patients and analyze cardiorespiratory and metabolic function during exercise to uncover exercise limitations beyond skeletal abnormalities. METHODS: Morquio A patients aged ≥7 years, able to walk >200 m in the 6-minute walk test (6MWT), received elosulfase alfa 2.0 mg/kg/week (N = 15) or 4.0 mg/kg/week (N = 10) for 52 weeks in the randomized, double-blind MOR-008 study ( ClinicalTrials...
November 21, 2017: JIMD Reports
https://www.readbyqxmd.com/read/29157341/glaucoma-in-u-s-civil-aviation-2005-2014
#13
Charles A DeJohn, William D Mills
INTRODUCTION: Until recently, glaucoma requiring treatment was disqualifying for U.S. pilots and required an aeromedical special issuance waiver. Since 2013 Aerospace Medical Examiners (AMEs) have been authorized to evaluate third-class pilots with mild glaucoma using similar protocols and issue medical certificates without a waiver if these criteria specified in the AME Guide are met. METHODS: The FAA's medical database was searched for pilots with glaucoma between 2005 and 2014...
December 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/29152531/erratum-publisher-s-note-restoring-vision-in-mice-with-retinal-degeneration-using-multicharacteristic-opsin
#14
Weldon Wright, Sivakumar Gajjeraman, Subrata Batabyal, Sanjay Pradhan, Sulagna Bhattacharya, Vasu Mahapatra, Ashutosh Tripathy, Samarendra Mohanty
[This corrects the article DOI: 10.1117/1.NPh.4.4.041412.].
October 2017: Neurophotonics
https://www.readbyqxmd.com/read/29138101/primary-antibiotic-resistance-of-helicobacter-pylori-in-chinese-patients-a-multi-region-prospective-7-year-study
#15
Dong-Sheng Liu, You-Hua Wang, Zhi-Rong Zeng, Zhen-Yu Zhang, Hong Lu, Jian-Ming Xu, Yi-Qi Du, Yan Li, Jiang-Bin Wang, San-Ping Xu, Ye Chen, Chun-Hui Lan, Hong Cheng, Ming-de Jiang, Ling-Xia Zhang, Li-Juan Huo, Shi-Yao Chen, Guo-Xin Zhang, Kai-Chun Wu, Xuan Zhu, You-Xiang Chen, Yin Zhu, Xu Shu, Yong Xie, Nong-Hua Lu
OBJECTIVES: To explore the characteristics of H. pylori resistance in China and the association between antibiotic resistance and several clinical factors. METHODS: H. pylori strains were collected from patients in 13 provinces/cities in China between 2010 and 2016. Demographic data including type of disease, geographic area, age, gender and isolation year were collected to analyse their association with antibiotic resistance. Antibiotic resistance was detected using the Epsilometer test and the Kirby-Bauer disk diffusion method...
November 11, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29117484/carotid-intraplaque-hemorrhage-imaging-with-quantitative-vessel-wall-t1-mapping-technical-development-and-initial-experience
#16
Haikun Qi, Jie Sun, Huiyu Qiao, Shuo Chen, Zechen Zhou, Xinlei Pan, Yishi Wang, Xihai Zhao, Rui Li, Chun Yuan, Huijun Chen
Purpose To develop a three-dimensional (3D) high-spatial-resolution time-efficient sequence for use in quantitative vessel wall T1 mapping. Materials and Methods A previously described sequence, simultaneous noncontrast angiography and intraplaque hemorrhage (SNAP) imaging, was extended by introducing 3D golden angle radial k-space sampling (GOAL-SNAP). Sliding window reconstruction was adopted to reconstruct images at different inversion delay times (different T1 contrasts) for voxelwise T1 fitting. Phantom studies were performed to test the accuracy of T1 mapping with GOAL-SNAP against a two-dimensional inversion recovery (IR) spin-echo (SE) sequence...
November 8, 2017: Radiology
https://www.readbyqxmd.com/read/29082432/oil-contamination-in-surface-sediment-of-anzali-wetland-in-iran-is-primarily-even-carbon-number-n-alkanes
#17
Rokhsareh Azimi-Yancheshmeh, Alireza Riyahi-Bakhtiari, Mozhgan Savabieasfahani
To determine the extent of oil contamination and biodegradation in Anzali Wetland of Iran, we examined aliphatic hydrocarbons in surface sediment of this area (n=20). Petroleum hydrocarbon levels (mean 1585 ± 1117; range 316 to 4358 μg g-(1) dry weight) were similar in value to reports from other highly contaminated areas, such as New York Bight, Saudi and Kuwaiti coasts of the Persian Gulf, and Dubai shorelines. Even carbon homologs dominated distribution of n-alkanes in surface sediment of Anzali, which is rarely reported elsewhere...
October 29, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29074495/outcome-of-anti-vascular-endothelial-growth-factor-therapy-for-neovascular-age-related-macular-degeneration-in-real-life-setting
#18
Maria Kataja, Pekko Hujanen, Heini Huhtala, Kai Kaarniranta, Anja Tuulonen, Hannele Uusitalo-Jarvinen
AIMS: To evaluate outcome of anti-vascular endothelial growth factor (VEGF) therapy for the treatment of neovascular age-related macular degeneration (nAMD) in the real-life setting and to compare incidence of ocular serious adverse events (SAE) after injections administered by nurses and physicians. METHODS: Retrospective, single-centre study. Medical records of patients receiving anti-VEGF treatment for nAMD between 2008 and 2013 with three-loading-dose regimen were evaluated...
October 26, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29065892/the-value-of-blood-cytokines-and-chemokines-in-assessing-copd
#19
Eric Bradford, Sean Jacobson, Jason Varasteh, Alejandro P Comellas, Prescott Woodruff, Wanda O'Neal, Dawn L DeMeo, Xingnan Li, Victor Kim, Michael Cho, Peter J Castaldi, Craig Hersh, Edwin K Silverman, James D Crapo, Katerina Kechris, Russell P Bowler
BACKGROUND: Blood biomarkers are increasingly used to stratify high risk chronic obstructive pulmonary disease (COPD) patients; however, there are fewer studies that have investigated multiple biomarkers and replicated in multiple large well-characterized cohorts of susceptible current and former smokers. METHODS: We used two MSD multiplex panels to measure 9 cytokines and chemokines in 2123 subjects from COPDGene and 1117 subjects from SPIROMICS. These biomarkers included: interleukin (IL)-2, IL-6, IL-8, IL-10, tumor necrosis factor (TNF)-α, interferon (IFN)-γ, eotaxin/CCL-11, eotaxin-3/CCL-26, and thymus and activation-regulated chemokine (TARC)/CCL-17...
October 24, 2017: Respiratory Research
https://www.readbyqxmd.com/read/29044584/direct-medical-costs-associated-with-the-extrahepatic-manifestations-of-hepatitis-c-virus-infection-in-france
#20
P Cacoub, M Vautier, A C Desbois, D Saadoun, Z Younossi
BACKGROUND: The economic impact of extrahepatic manifestations of hepatitis C virus (HCV) infection remains unknown for France. AIM: To estimate the prevalence of extrahepatic manifestations of HCV and the direct medical costs associated with them. METHODS: Estimates of 13 extrahepatic manifestations prevalence were obtained from (1) a retrospective data analysis of HCV-infected patients in a specialised centre and the baseline prevalence in the general French population and (2) an international systematic review...
January 2018: Alimentary Pharmacology & Therapeutics
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