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Anophthalmic

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https://www.readbyqxmd.com/read/28711015/hydrophilic-surface-modification-of-poly-methyl-methacrylate-based-ocular-prostheses-using-poly-ethylene-glycol-grafting
#1
JaeSang Ko, Kanghee Cho, Sang Won Han, Hyung Kyung Sung, Seung Woon Baek, Won-Gun Koh, Jin Sook Yoon
Ocular prostheses are custom-made polymeric inserts that can be placed in anophthalmic sockets for cosmetic rehabilitation. Prosthetic eye wearers have reduced tear amount, and they often experience dry eye symptoms including dryness, irritation, discomfort, and discharge. Most modern ocular prostheses are made of poly(methyl methacrylate) (PMMA), which is highly hydrophobic. Previous research has shown that improving the wettability of contact lens materials decreases its wearers discomfort by increasing lubrication...
July 8, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28706880/a-novel-method-for-the-management-of-anophthalmic-socket
#2
Srinivasa B Rao, Savita Akki, Deepak Kumar, Sunil Kumar Mishra
An orbital defect causes severe facial asymmetry and disfigurement that result in an immense emotional trauma to the patient and is also associated with economic, esthetic, and psychological problems. A prosthetic replacement is the treatment of choice in helping individual to return to his normal life by producing an acceptable and lifelike appearance. This case report describes the critical areas of fabrication of ocular prosthesis for a patient with missing right eye due to trauma to eye ball in an accident...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28675567/a-modulatory-role-of-the-rax-homeobox-gene-in-mature-pineal-gland-function-investigating-the-photoneuroendocrine-circadian-system-of-a-rax-conditional-knockout-mouse
#3
Kristian Rohde, Tenna Bering, Takahisa Furukawa, Martin Fredensborg Rath
The retinal and anterior neural fold homeobox gene (Rax) controls development of the eye and the forebrain. Postnatal expression of Rax in the brain is restricted to the pineal gland, a forebrain structure devoted to melatonin synthesis. The role of Rax in pineal function is unknown. In order to investigate the role of Rax in pineal function while circumventing forebrain abnormalities of the global Rax knockout, we generated an eye and pineal-specific Rax conditional knockout mouse. Deletion of Rax in the pineal gland did not affect morphology of the gland, suggesting that Rax is not essential for pineal gland development...
July 4, 2017: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28603245/checklist-of-the-micro-and-anophthalmic-soil-dwelling-weevils-of-the-world-coleoptera-curculionidae
#4
Juan J Morrone, Peter Hlaváč
A checklist of the soil-dwelling microphthalmic and anophthalmic weevils of the world is presented. A total of 485 species in 85 genera are recognised, distributed over eight subfamilies and 26 tribes. The subfamilies are arranged in the currently accepted phylogenetic sequence, whereas the tribes, genera and species are listed in alphabetical order. For each species, the type locality and the geographical distribution by country is provided. Particularly diversified taxa are Entiminae: Otiorhynchini (125 species), Brachycerinae: Raymondionymini (90 species), Cossoninae: Dryotribini (59 species), Cryptorhynchinae: Torneumatini (58 species) and Molytinae: Lymantini (39 species)...
March 8, 2017: Zootaxa
https://www.readbyqxmd.com/read/28601909/study-of-conjunctival-flora-in-anophthalmic-patients-influence-on-the-comfort-of-the-socket
#5
Alvaro Toribio, Teresa Marrodán, Isabel Fernández-Natal, Honorina Martínez-Blanco, Leandro Rodríguez-Aparicio, Miguel Á Ferrero
PURPOSE: To investigate the relationship between conjunctival flora and comfort of the socket in anophthalmic patients. METHODS: A cross-sectional clinical study including 60 patients with unilateral anophthalmia who wear a prosthetic eye. From each patient three microbiological samples were taken from the lower conjunctival sac (healthy eye, pre-prosthesis, and retro-prosthesis space of socket). The 180 samples obtained were cultured. Samples from a randomized subgroup of 29 patients were measured by spectrophotometry at 540 nm after 48 h of growth, to determine their microbial density (MD)...
June 10, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28584422/an-innovative-and-simple-approach-to-fabricate-a-hollow-ocular-prosthesis-with-functional-lubricant-reservoir-a-solution-to-artificial-eye-comfort
#6
Aditya Anil Kavlekar, Meena Ajay Aras, Vidya Chitre
The loss of an eye is an emotional and psychological setback to the patient. An ocular prosthesis is created to restore the lost anatomical structure and to correct the cosmetic defect. The tear reflexes do not function at optimal levels in anophthalmic sockets which make prosthesis wear uncomfortable. This case report presents an innovative hollow ocular prosthesis with functional lubricant reservoir which upon normal blinking would draw the lubricant from the reservoir through an exit hole which spreads over the prosthesis allowing a comfortable and long duration of prosthesis wear...
April 2017: Journal of Indian Prosthodontic Society
https://www.readbyqxmd.com/read/28582288/a-survey-of-ocular-prosthetics-rehabilitation-in-the-united-kingdom-part-2-anophthalmic-patients-satisfaction-and-acceptance
#7
Muhanad M Hatamleh, Ahmad A Alnazzawi, Mojgan Abbariki, Noor Alqudah, Anne E Cook
AIM: Ocular prostheses are integral for anophthalmic patients. Part 1 of this study reported that patients' aetiology, opinions, and attitudes significantly affected their prosthetic eyes experience. Part 2 investigates the patient satisfaction and acceptance in light of some of the aetiological demographics reported in Part 1. METHODOLOGY: One hundred sixty questionnaires were delivered to anophthalmic patients attending oculoplastic clinic. Etiological aspects presented in the questionnaire were disseminated in part 1...
June 2, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28530256/can-the-onset-of-orbital-cancer-be-the-result-of-a-prosthetic-eye
#8
A Croce, V Mastronardi, M Laus, E Festa Kotelnikova
Orbital exenteration is a disfiguring procedure performed for unresponsive orbital infections and control of recurrent benign tumours and malignancies arising from the eyelids (basal cell carcinoma, squamous cell carcinoma, conjunctival malignant melanoma), lachrymal glands (adenoid cystic carcinoma) or surrounding sinuses. In extremely rare cases the use of a prosthetic eye after enucleation can lead to anophthalmic socket tumours. We report the case of a 54-year-old man who had left eye enucleation due to recurring events of retinal detachment and who developed an invasive fast growing epidermoid carcinoma 30 years later...
May 22, 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28476055/pv16-positive-invasive-conjunctival-squamous-cell-carcinoma-in-an-anophthalmic-socket
#9
Eric D Gaier, Frederick A Jakobiec, Anna M Stagner, Kevin Emerick, Michael K Yoon
Squamous cell carcinoma arising from conjunctiva in the anophthalmic socket decades following enucleation is rare, but has been previously described. The authors report the first case associated with human papillomavirus (serotype 16) with regional metastases. The patient ultimately underwent orbital exenteration along with parotidectomy and neck dissection which revealed positive lymph nodes. The literature is reviewed relating to this uncommon entity and its management with an analysis of potential contributing risk factors...
May 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28318922/surgical-rehabilitation-for-anophthalmic-sockets-devoid-of-orbital-implant
#10
Doo-Ri Eo, Yoon-Duck Kim, Kyung In Woo
PURPOSE: To determine the necessity of rehabilitative surgical procedures for no implant anophthalmic sockets, and predictive factors of corrective operations after secondary orbital implantation. MATERIAL AND METHODS: Nineteen unilateral anophthalmic patients without orbital implant were included. The distance of eyebrow, upper eyelid margin, and lower eyelid margin from the horizontal medial canthal line (BM, UM, and LM, respectively) was measured using photographs...
May 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28243018/surgical-outcomes-of-porcine-acellular-dermis-graft-in-anophthalmic-socket-comparison-with-oral-mucosa-graft
#11
COMPARATIVE STUDY
Livia Teo, Young Jun Woo, Dong Kyu Kim, Chang Yeom Kim, Jin Sook Yoon
PURPOSE: We describe our experience with the Permacol graft in anophthalmic socket reconstruction, and compare it to the autologous buccal mucosal graft, emphasizing the postoperative vascularization and contraction of each graft. METHODS: This was a retrospective comparative study. We measured the time necessary for the graft surface to be completely vascularized, as well as the fornix depth of the conjunctival sac in anophthalmic patients. RESULTS: Ten patients underwent Permacol graft reconstruction, with 44 undergoing buccal mucosal graft reconstruction...
February 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/28145922/survey-of-ocular-prosthetics-rehabilitation-in-the-united-kingdom-part-1-anophthalmic-patients-aetiology-opinions-and-attitudes
#12
Muhanad M Hatamleh, Mojgan Abbariki, Noor Alqudah, Anne E Cook
PURPOSE: Ocular prostheses are constructed to aid cosmetic, functional, and psychological rehabilitation of anophthalmic patients. Part-1 of this study aimed to evaluate anophthalmic patients' opinions, attitudes, and experience about aspects related to their postfit ocular prostheses. METHODS: One hundred sixty questionnaires were delivered to anophthalmic patients inquiring about different information such as age, gender, occupation, eye-loss cause, prosthesis type, prosthesis-wearing frequency, prosthesis-cleaning frequency, and problems encountered...
January 31, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27898617/management-of-inflammation-and-periocular-malignancy-in-the-anophthalmic-socket
#13
Caroline W Vargason, Louise A Mawn
No abstract text is available yet for this article.
2017: International Ophthalmology Clinics
https://www.readbyqxmd.com/read/27833429/occurrence-of-cavernicolous-ground-beetles-in-anhui-province-eastern-china-coleoptera-carabidae-trechinae
#14
Jie Fang, Wenbo Li, Mingyi Tian
Two new species of anophthalmic ground beetles belonging to the subfamily Trechinae are described: Cimmeritodes (Zhecimmerites) parvus Tian & Li, sp. n. and Wanoblemus wui Tian & Fang, gen. n., sp. n. Both were discovered in the limestone caves of Anhui Province in eastern China. Cimmeritodes (Zhecimmerites) parvus was found in caves Ziwei Dong, Xianren Dong and Qingtai Dong, whereas Wanoblemus wui was discovered in cave Baiyun Dong. This is the first record of cavernicolous ground beetles in Anhui Province, eastern China...
2016: ZooKeys
https://www.readbyqxmd.com/read/27820878/integrated-versus-non-integrated-orbital-implants-for-treating-anophthalmic-sockets
#15
REVIEW
Silvana Schellini, Regina El Dib, Leandro Re Silva, Joyce G Farat, Yuqing Zhang, Eliane C Jorge
BACKGROUND: Anophthalmia is the absence of one or both eyes, and it can be congenital (i.e. a birth defect) or acquired later in life. There are two main types of orbital implant: integrated, whereby the implant receives a blood supply from the body that allows for the integration of the prosthesis within the tissue; and non-integrated, where the implant remains separate. Despite the remarkable progress in anophthalmic socket reconstruction and in the development of various types of implants, there are still uncertainties about the real roles of integrated (hydroxyapatite (HA), porous polyethylene (PP), composites) and non-integrated (polymethylmethacrylate (PMMA)/acrylic and silicone) orbital implants in anophthalmic socket treatment...
November 7, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27785411/gene-mapping-in-an-anophthalmic-pedigree-of-a-consanguineous-pakistani-family-opened-new-horizons-for-research
#16
S Saleha, M Ajmal, S Zafar, A Hameed
Clinical anophthalmia is a rare inherited disease of the eye and phenotype refers to the absence of ocular tissue in the orbit of eye. Patients may have unilateral or bilateral anophthalmia, and generally have short palpebral fissures and small orbits. Anophthalmia may be isolated or associated with a broader syndrome and may have genetic or environmental causes. However, genetic cause has been defined in only a small proportion of cases, therefore, a consanguineous Pakistani family of the Pashtoon ethnic group, with isolated clinical anophthalmia was investigated using linkage mapping...
July 1, 2016: Balkan Journal of Medical Genetics: BJMG
https://www.readbyqxmd.com/read/27688179/evisceration-surgery-in-a-highly-specialized-center-in-mexico-a-retrospective-study-of-7-years-of-experience
#17
M G Arellano-Ganem, F Zuazo, M González, A Abdala, O Olvera-Morales, J L Tovilla-Canales, Á Nava-Castañeda
INTRODUCTION: Evisceration is currently becoming the technique of choice in the treatment of certain eye diseases, including, among others, painful blind eye and endophthalmitis. The most widely used implants are currently the hydroxyapatite and porous polyethylene for the rehabilitation of the anophthalmic socket. OBJECTIVE: To describe the indications, type of implant material used, and complications in evisceration surgery. METHODS: A retrospective, observational, descriptive study based on clinical records of patients that underwent evisceration between 2008 and 2015 in the Instituto Fundación Conde de Valenciana, Mexico...
September 26, 2016: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/27672305/successful-conjunctival-socket-expansion-in-anophthalmic-patients-until-the-age-of-2-years-an-outpatient-procedure
#18
Rania Assem El Essawy, Sameh Hassan Abdelbaky
PURPOSE: To report the results of a simple outpatient method for soft tissue socket expansion in young children with congenital anophthalmos. METHODS: Seventeen congenital anophthalmic sockets of 15 infants of a mean age of 4.2±4.4 months were fitted with specially designed serial solid acrylic shapes or hydrogel expanders using cyanoacrylate for eyelids closure when using the latter. RESULTS: At the age of 2 years, the mean horizontal eyelid length increased from a mean of 11...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27615918/endogean-and-cavernicolous-coleoptera-of-the-balkans-xvii-a-new-species-of-the-genus-speluncarius-reitter-1886-coleoptera-carabidae-harpalinae-pterostichini-from-croatia
#19
Peter Hlaváč, Ján Lakota, Dávid Čeplík
The genus Speluncarius Reitter, 1886 (Harpalinae, Pterostichini) is made up by anophthalmous or almost blind species. The genus is related to Tapinopterus Schaum, 1858, which contains numerous species from the Balkan-Anatolian region and have more or less developed eyes. Speluncarius is distributed in the Western Palaearctic region; 26 species and one subspecies are known from Italy, the Balkan Peninsula and Turkey. The genus is classified in five subgenera, Elasmopterus Kraatz, 1886 (6 spp.); Hypogearius Jeannel, 1953 (3 spp...
September 2, 2016: Zootaxa
https://www.readbyqxmd.com/read/27612842/orbital-implants-state-of-the-art-review-with-emphasis-on-biomaterials-and-recent-advances
#20
REVIEW
Francesco Baino, Isabel Potestio
In the treatment of severe oculo-orbital traumas, intraocular malignancies or other life-threatening conditions it is sometimes necessary to surgically remove the patient's diseased eye. Following the removal of the eye, an orbital implant is inserted into the anophthalmic socket in order to provide satisfactory volume replacement and restore the aesthetic appearance of a normal eye. Over the last decades, the implant design and the criteria of materials selection evolved from simple non-porous polymeric sphere to devices with more complex shape and functionalities for ensuring better clinical outcomes in the long-term...
December 1, 2016: Materials Science & Engineering. C, Materials for Biological Applications
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