keyword
MENU ▼
Read by QxMD icon Read
search

tensor network

keyword
https://www.readbyqxmd.com/read/29033978/integrative-analysis-of-transcription-factor-combinatorial-interactions-using-a-bayesian-tensor-factorization-approach
#1
Yusen Ye, Lin Gao, Shihua Zhang
Transcription factors play a key role in transcriptional regulation of genes and determination of cellular identity through combinatorial interactions. However, current studies about combinatorial regulation is deficient due to lack of experimental data in the same cellular environment and extensive existence of data noise. Here, we adopt a Bayesian CANDECOMP/PARAFAC (CP) factorization approach (BCPF) to integrate multiple datasets in a network paradigm for determining precise TF interaction landscapes. In our first application, we apply BCPF to integrate three networks built based on diverse datasets of multiple cell lines from ENCODE respectively to predict a global and precise TF interaction network...
2017: Frontiers in Genetics
https://www.readbyqxmd.com/read/29033027/anhedonia-following-early-life-adversity-involves-aberrant-interaction-of-reward-and-anxiety-circuits-and-is-reversed-by-partial-silencing-of-amygdala-corticotropin-releasing-hormone-gene
#2
Jessica L Bolton, Jenny Molet, Limor Regev, Yuncai Chen, Neggy Rismanchi, Elizabeth Haddad, Derek Z Yang, Andre Obenaus, Tallie Z Baram
BACKGROUND: Anhedonia, the diminished ability to experience pleasure, is an important dimensional entity linked to depression, schizophrenia, and other emotional disorders, but its origins and mechanisms are poorly understood. We have previously identified anhedonia, manifest as decreased sucrose preference and social play, in adolescent male rats that experienced chronic early-life adversity/stress (CES). Here we probed the molecular, cellular, and circuit processes underlying CES-induced anhedonia and tested them mechanistically...
September 7, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/29031764/combined-resting-state-functional-magnetic-resonance-imaging-and-diffusion-tensor-imaging-study-in-patients-with-idiopathic-restless-legs-syndrome
#3
Yaoyao Zhuo, Yuncheng Wu, Yanhong Xu, Lunbo Lu, Ting Li, Xifu Wang, Kangan Li
OBJECTIVE: Restless legs syndrome (RLS) is a common neurological disorder characterized by an urge to move the legs along with paraesthesia deep within them. In this study, we aimed to use diffusion tensor imaging (DTI) and regional homogeneity (ReHo) to investigate the changes in regional spontaneous brain activity change for RLS patients against age- and gender-matched normal control (NC) subjects. METHODS: A total of 35 RLS patients and 27 age- and gender-matched NC subjects were recruited for group comparison research that used DTI and ReHo techniques...
October 2017: Sleep Medicine
https://www.readbyqxmd.com/read/29030921/development-of-short-range-white-matter-in-healthy-children-and-adolescents
#4
Adeoye A Oyefiade, Stephanie Ameis, Jason P Lerch, Conrad Rockel, Kamila U Szulc, Nadia Scantlebury, Alexandra Decker, Jaleel Jefferson, Simon Spichak, Donald J Mabbott
Neural communication is facilitated by intricate networks of white matter (WM) comprised of both long and short range connections. The maturation of long range WM connections has been extensively characterized, with projection, commissural, and association tracts showing unique trajectories with age. There, however, remains a limited understanding of age-related changes occurring within short range WM connections, or U-fibers. These connections are important for local connectivity within lobes and facilitate regional cortical function and greater network economy...
October 14, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29028937/abnormal-structural-brain-connectome-in-individuals-with-preclinical-alzheimer-s-disease
#5
Joana B Pereira, Danielle van Westen, Erik Stomrud, Tor Olof Strandberg, Giovanni Volpe, Eric Westman, Oskar Hansson
Alzheimer's disease has a long preclinical phase during which amyloid pathology and neurodegeneration accumulate in the brain without producing overt cognitive deficits. It is currently unclear whether these early disease stages are associated with a progressive disruption in the communication between brain regions that subsequently leads to cognitive decline and dementia. In this study we assessed the organization of structural networks in cognitively normal (CN) individuals harboring amyloid pathology (A+N-), neurodegeneration (A-N+), or both (A+N+) from the prospective and longitudinal Swedish BioFINDER study...
October 3, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28992269/white-matter-correlates-of-psychopathic-traits-in-a-female-community-sample
#6
Philip Lindner, Meenal Budhiraja, Johan Westerman, Ivanka Savic, Jussi Jokinen, Jari Tiihonen, Sheilagh Hodgins
Psychopathy comprises interpersonal, affective, lifestyle and antisocial facets that vary dimensionally in the population and are associated with criminal offending and adverse psychosocial outcomes. Evidence associating these facets with white matter microstructure of the uncinate fasciculus and the cingulum tracts is inconsistent and derives principally from studies of male offenders. In a sample of 99 young women presenting a range of scores on the Psychopathy Checklist: Screening Version, we used Diffusion Tensor Imaging, tractography and Tract-Based Spatial Statistics to investigate microstructure across the brain and of the uncinate fasciculus and cingulum...
September 1, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28988022/white-matter-and-schizophrenia-a-meta-analysis-of-voxel-based-morphometry-and-diffusion-tensor-imaging-studies
#7
Enrico Vitolo, Mona Karina Tatu, Claudia Pignolo, Franco Cauda, Tommaso Costa, Agata Ando', Alessandro Zennaro
Voxel-based morphometry (VBM) and diffusion tensor imaging (DTI) are the most implemented methodologies to detect alterations of both gray and white matter (WM). However, the role of WM in mental disorders is still not well defined. We aimed at clarifying the role of WM disruption in schizophrenia and at identifying the most frequently involved brain networks. A systematic literature search was conducted to identify VBM and DTI studies focusing on WM alterations in patients with schizophrenia compared to control subjects...
September 23, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28985720/effects-of-homocysteine-on-white-matter-diffusion-parameters-in-alzheimer-s-disease
#8
Chen-Chang Lee, Shih-Wei Hsu, Chi-Wei Huang, Wen-Neng Chang, Sz-Fan Chen, Ming-Kung Wu, Chiung-Chih Chang, Lain-Chyr Hwang, Po-Chou Chen
BACKGROUND: The clinical features of Alzheimer's disease (AD) are related to brain network degeneration, and hyperhomocysteinemia is related to greater white matter hyperintensities. We investigated the changes in four diffusion tensor imaging parameters in the white matter of patients with early stage AD, examined their associations with homocysteine level, and tested the clinical significance of the diffusion tensor imaging parameters and homocysteine level in correlation analysis with cognitive test scores...
October 6, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28982687/dlx5-fgf10-signaling-cascade-controls-cranial-neural-crest-and-myoblast-interaction-during-oropharyngeal-patterning-and-development
#9
Hideki Sugii, Alexandre Grimaldi, Jingyuan Li, Carolina Parada, Thach Vu-Ho, Jifan Feng, Junjun Jing, Yuan Yuan, Yuxing Guo, Hidefumi Maeda, Yang Chai
Craniofacial development depends on cell-cell interactions, coordinated cellular movement and differentiation under the control of regulatory gene networks, which include the distal-less (Dlx) gene family. However, the functional significance of Dlx5 in patterning the oropharyngeal region has remained unknown. Here we show that loss of Dlx5 leads to a shortened soft palate and an absence of the levator veli palatini, palatopharyngeus, and palatoglossus muscles that are derived from the 4(th) pharyngeal arch (PA), but the tensor veli palatini, derived from the 1(st) PA, is unaffected...
October 5, 2017: Development
https://www.readbyqxmd.com/read/28976354/exciton-transport-in-the-pe545-complex-insight-from-atomistic-qm-mm-based-quantum-master-equations-and-elastic-network-models
#10
Sima Pouyandeh, Stefano Iubini, Sandro Jurinovich, Yasser Omar, Benedetta Mennucci, Francesco Piazza
In this paper we work out a parameterization of the environment noise within the Haken-Strobl-Reinenker (HSR) model for the PE545 light-harvesting complex based on atomic-level quantum mechanics/molecular mechanics (QM/MM) simulations. We use this approach to investigate the role of different auto- and cross-correlations in the HSR noise tensor, confirming that site-energy autocorrelations (pure dephasing) terms dominate the noise-induced exciton mobility enhancement, followed by site energy-coupling cross-correlations for specific triplets of pigments...
October 4, 2017: Physical Biology
https://www.readbyqxmd.com/read/28970540/microstructural-network-alterations-of-olfactory-dysfunction-in-newly-diagnosed-parkinson-s-disease
#11
Ming-Ching Wen, Zheyu Xu, Zhonghao Lu, Ling Ling Chan, Eng King Tan, Louis C S Tan
Olfactory dysfunction is a robust and early sign for Parkinson's disease (PD). Previous studies have revealed its association with dementia and related neural changes in PD. Yet, how olfactory dysfunction affects white matter (WM) microstructure in newly diagnosed and untreated PD remains unclear. Here we comprehensively examined WM features using unbiased whole-brain analyses. 88 newly diagnosed PD patients without dementia (70 with hyposmia and 18 without hyposmia) and 33 healthy controls underwent clinical assessment and diffusion tensor imaging (DTI) scanning...
October 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28969487/brain-structural-network-topological-alterations-of-the-left-prefrontal-and-limbic-cortex-in-psychogenic-erectile-dysfunction
#12
Jianhuai Chen, Yun Chen, Qingqiang Gao, Guotao Chen, Yutian Dai, Zhijian Yao, Qing Lu
Despite increasing understanding of the cerebral functional changes and structural abnormalities in erectile dysfunction, alterations in the topological organization of brain networks underlying psychogenic erectile dysfunction (pED) remain unclear. Here, based on the diffusion tensor image data of 25 pED patients and 26 healthy controls, we investigated the topological organization of brain structural networks and its correlations with the clinical variables using the graph theoretical analysis. Psychogenic ED displayed a preserved overall small-world organization and exhibited a less connectivity strength in the left inferior frontal gyrus, amygdale and the right inferior temporal gyrus...
October 2, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28967386/structural-neuroimaging-of-anorexia-nervosa-future-directions-in-the-quest-for-mechanisms-underlying-dynamic-alterations
#13
REVIEW
Joseph A King, Guido K W Frank, Paul M Thompson, Stefan Ehrlich
Anorexia nervosa (AN) is a serious eating disorder characterized by self-starvation and extreme weight loss. Pseudoatrophic brain changes are often readily visible in individual brain scans, and AN may be a valuable model disorder to study structural neuroplasticity. Structural magnetic resonance imaging studies have found reduced gray matter volume and cortical thinning in acutely underweight patients to normalize following successful treatment. However, some well-controlled studies have found regionally greater gray matter and persistence of structural alterations following long-term recovery...
August 24, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/28964628/structural-connectome-alterations-in-prodromal-and-de-novo-parkinson-s-disease-patients
#14
Ming-Ching Wen, Hannah S E Heng, Jung-Lung Hsu, Zheyu Xu, Gerald M Liew, Wing Lok Au, Ling Ling Chan, Louis C S Tan, Eng King Tan
BACKGROUND: Although the clinical signs of prodromal Parkinson's disease (PD) have been identified, little is known about the neural features of the prodromal phase of PD (proPD). The aim of this study was to examine the structural network alterations from healthy aging to proPD and to early PD. METHODS: 181 non-demented and non-depressed participants comprising 55 healthy controls (HCs), 20 proPDs, and 106 de novo PD patients (dPDs) were included in the study and underwent clinical assessment and diffusion tensor imaging scanning...
September 21, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28960762/white-matter-integrity-of-central-executive-network-correlates-with-enhanced-brain-reactivity-to-smoking-cues
#15
Yanzhi Bi, Kai Yuan, Dahua Yu, Ruonan Wang, Min Li, Yangding Li, Jinquan Zhai, Wei Lin, Jie Tian
The attentional bias to smoking cues contributes to smoking cue reactivity and cognitive declines underlines smoking behaviors, which were probably associated with the central executive network (CEN). However, little is known about the implication of the structural connectivity of the CEN in smoking cue reactivity and cognitive control impairments in smokers. In the present study, the white matter structural connectivity of the CEN was quantified in 35 smokers and 26 non-smokers using the diffusion tensor imaging and deterministic fiber tractography methods...
September 28, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28954333/-the-altered-topology-of-brain-structural-network-in-patients-with-acute-stress-response-after-traffic-accident
#16
Y F Weng, R F Qi, X D Zhang, L Zhang, J Ke, Y Zhong, F Chen, Q Xu, G M Lu
Objective: To explore the changes of brain activities in traffic accident survivors with acute stress response (ASR) within a week by using complex networks analysis method based on graph-theory, and to find out the alteration of topological properties in structural brain network. Method: From January, 2013 to February, 2016, twenty traffic accidents survivors with acute stress disorders (Acute Stress Disorder Interview, ASDI>3)and twenty healthy controls underwent the 3T diffusion tensor imaging (DTI) magnetic resonance imaging scan in Nanjing General Hospital...
September 19, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28950550/versatile-and-efficient-pore-network-extraction-method-using-marker-based-watershed-segmentation
#17
Jeff T Gostick
Obtaining structural information from tomographic images of porous materials is a critical component of porous media research. Extracting pore networks is particularly valuable since it enables pore network modeling simulations which can be useful for a host of tasks from predicting transport properties to simulating performance of entire devices. This work reports an efficient algorithm for extracting networks using only standard image analysis techniques. The algorithm was applied to several standard porous materials ranging from sandstone to fibrous mats, and in all cases agreed very well with established or known values for pore and throat sizes, capillary pressure curves, and permeability...
August 2017: Physical Review. E
https://www.readbyqxmd.com/read/28950219/increase-in-gray-matter-volume-and-white-matter-fractional-anisotropy-in-the-motor-pathways-of-patients-with-secondarily-generalized-neocortical-seizures
#18
Yue-Loong Hsin, Tomor Harnod, Cheng-Siu Chang, Syu-Jyun Peng
PURPOSE: Convulsive motor activity is a clinical manifestation of secondarily generalized seizures evolving from different focal regions. The way in which the motor seizures present themselves is not very different from most of the generalized seizures in and between epilepsy patients. This might point towards the involvement of motor-related cortices and corticospinal pathway for wide spread propagation of epileptic activity. Our aim was to identify changes in the cerebral structures and to correlate clinical variables with structural changes particularly in the motor-related cortices and pathway of patients with generalized convulsions from different seizure foci...
September 20, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28949736/frustrated-magnetism-of-dipolar-molecules-on-a-square-optical-lattice-prediction-of-a-quantum-paramagnetic-ground-state
#19
Haiyuan Zou, Erhai Zhao, W Vincent Liu
Motivated by the experimental realization of quantum spin models of polar molecule KRb in optical lattices, we analyze the spin 1/2 dipolar Heisenberg model with competing anisotropic, long-range exchange interactions. We show that, by tilting the orientation of dipoles using an external electric field, the dipolar spin system on square lattice comes close to a maximally frustrated region similar, but not identical, to that of the J_{1}-J_{2} model. This provides a simple yet powerful route to potentially realize a quantum spin liquid without the need for a triangular or kagome lattice...
August 4, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28949669/bridging-perturbative-expansions-with-tensor-networks
#20
Laurens Vanderstraeten, Michaël Mariën, Jutho Haegeman, Norbert Schuch, Julien Vidal, Frank Verstraete
We demonstrate that perturbative expansions for quantum many-body systems can be rephrased in terms of tensor networks, thereby providing a natural framework for interpolating perturbative expansions across a quantum phase transition. This approach leads to classes of tensor-network states parametrized by few parameters with a clear physical meaning, while still providing excellent variational energies. We also demonstrate how to construct perturbative expansions of the entanglement Hamiltonian, whose eigenvalues form the entanglement spectrum, and how the tensor-network approach gives rise to order parameters for topological phase transitions...
August 18, 2017: Physical Review Letters
keyword
keyword
92751
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"