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https://www.readbyqxmd.com/read/28198293/locating-difficult-veins-for-venepuncture-and-cannulation
#1
Sally Jane Shaw
Vein location and assessment are essential to improve the success rates for vascular access. However, problems remain with first attempt success rates for peripheral cannulation and locating difficult veins. Practitioners may not be aware of developments in technology and aids to assist in the location and assessment of veins to achieve vascular access. This article provides an overview of two vein location aids that can be used to locate difficult veins: the IV-eye vein imager and the Vacuderm tourniquet. It discusses the patient factors that can increase the difficulty of vein assessment and location, and emphasises the importance of vessel health and preservation, and vein palpation...
February 15, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28196306/effects-of-isoflurane-anesthesia-and-intravenous-morphine-self-administration-on-regional-glucose-metabolism-18-f-fdg-pet-of-male-sprague-dawley-rats
#2
Thomas Y Park, Kevin S Nishida, Colin M Wilson, Shalini Jaiswal, Jessica Scott, Andrew R Hoy, Reed G Selwyn, Bernard J Dardzinski, Kwang H Choi
Although certain drugs of abuse are known to disrupt brain glucose metabolism (BGluM), the effects of opiates on BGluM are not well characterized. Moreover, preclinical positron emission tomography (PET) studies anesthetize animals during the scan, which limits clinical applications. We investigated the effects of 1) isoflurane anesthesia and 2) intravenous morphine self-administration (MSA) on BGluM in rats. Jugular vein cannulated adult male Sprague-Dawley rats self-administered either saline (SSA) or morphine (0...
February 14, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28188033/success-and-safety-of-endoscopic-retrograde-cholangiopancreatography-in-children
#3
Jordan D Rosen, Rebecca S Lane, Jose M Martinez, Eduardo A Perez, Jun Tashiro, Amy E Wagenaar, Robert M Van Haren, Ashwini Kumar, Juan E Sola
PURPOSE: Despite its diagnostic and therapeutic utility, endoscopic retrograde cholangiopancreatography (ERCP) is underutilized in children. METHODS: Patients younger than 18years undergoing ERCP from 2000 to 2014 at a children's hospital were identified. Patient characteristics and outcomes were evaluated. RESULTS: Overall, 215 ERCPs (78% therapeutic) were performed in 184 patients. Our cohort was 67% female, with a median age (IQR) of 14 (8) years...
February 1, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28165578/a-randomized-study-of-training-with-large-versus-small-vessel-size-on-successful-ultrasound-guided-peripheral-venous-access
#4
Joshua Davis, Timothy Faust, Azeem Tajani, Amanda Bates, Jenna Jarriel, Arthur Au, Jason Matthew Fields
PURPOSE: Our objective was to investigate whether training on phantoms with smaller or larger vessels would improve success rate in novice medical students learning this skill. METHODS: Medical students who participated in a voluntary, extracurricular ultrasound training day were asked to participate in the study as part of their procedural training. They were given a standardized education and demonstration of how to use ultrasound to place a peripheral intravenous (IV) catheter...
January 31, 2017: Journal of Vascular Access
https://www.readbyqxmd.com/read/28131574/the-effects-of-fructose-and-phosphate-infusions-on-dry-matter-intake-of-lactating-cows
#5
Roni Yair, Michael S Allen
The objective of this study was to examine the effects of fructose and phosphate (Pi) infusions on dry matter intake by dairy cows to further understand the mechanisms controlling feed intake related to hepatic energy status. We performed 3 experiments in which we infused fructose and Pi intravenously or abomasally to Holstein cows. The first experiment used 8 cows (4-8 d postpartum) in a duplicated 4 × 4 Latin square experiment with 1 square of multiparous and 1 square of primiparous cows. A 2 × 2 factorial arrangement of treatments was used including jugular infusions of solutions (1 L/h) containing fructose or glucose (0...
January 25, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28130888/first-time-success-with-needle-procedures-was-higher-with-a-warm-lidacaine-and-tetracaine-patch-than-an-eutectic-mixture-of-lidocaine-and-prilocaine-cream
#6
Giorgio Cozzi, Fabio Borrometi, Franca Benini, Elena Neri, Francesca Rusalen, Loredana Celentano, Davide Zanon, Silvana Schreiber, Luca Ronfani, Egidio Barbi
AIM: More than 50% of children report apian during venipuncture or intravenous cannulation and using local anaesthetics before needle procedures can lead to different success rates. This study examined how many needle procedures were successful at the first attempt when children received either a warm lidocaine and tetracaine patch or an eutectic mixture of lidocaine and prilocaine (EMLA) cream. METHODS: We conducted this multicentre randomised controlled trial at three tertiary-level children's hospitals in Italy in 2015...
January 27, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28127013/can-intravenous-conscious-sedation-with-midazolam-be-effective-at-facilitating-surgical-dentistry-in-adolescent-orthodontic-patients-a-service-evaluation
#7
A J Stamp, M L Dorman, C R Vernazza, G Deeming, C Reid, K E Wilson, N M Girdler
Background Surgical dentistry during orthodontic care often occurs in adolescence and may involve surgical removal or exposure of teeth. The invasive nature of treatment, combined with dental anxiety, means care can often be provided under general anaesthesia (GA). Best-practice guidelines however endorse conscious sedation as an alternative, where appropriate. Although a limited number of studies have shown safe and effective use of intravenous conscious sedation (IVCS) with midazolam in this cohort, robust evidence to support routine use is lacking...
January 27, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28111492/adaptive-kinematic-control-of-a-robotic-venipuncture-device-based-on-stereo-vision-ultrasound-and-force-guidance
#8
Max L Balter, Alvin I Chen, Timothy J Maguire, Martin L Yarmush
Robotic systems have slowly entered the realm of modern medicine; however, outside the operating room, medical robotics has yet to be translated to more routine interventions such as blood sampling or intravenous fluid delivery. In this paper, we present a medical robot that safely and rapidly cannulates peripheral blood vessels-a procedure commonly known as venipuncture. The device uses near-infrared and ultrasound imaging to scan and select suitable injection sites, and a 9-DOF robot to insert the needle into the center of the vessel based on image and force guidance...
February 2017: IEEE Transactions on Industrial Electronics
https://www.readbyqxmd.com/read/28093376/a-new-angle-and-its-relationship-with-early-fixation-failure-of-femoral-neck-fractures-treated-with-three-cannulated-compression-screws
#9
Y L Zhang, W Zhang, C Q Zhang
BACKGROUND: The Pauwels angle has been used widely, however an accurate evaluation of this angle is difficult because of deformity of the affected lower extremity. Therefore we designed a new measurement of the orientation of femoral neck fracture and applied this in a retrospective study to assess: (1) its reproducibility, (2) its advantages compared with the Pauwels angle, (3) its relationship with the short-term prognosis treated with three cannulated compression screws. HYPOTHESIS: This new measurement is reproducible and has some reference meaning for the treatment of femoral neck fractures...
January 16, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28072500/ultrasound-guided-intracardiac-xenotransfusion-of-canine-packed-red-blood-cells-and-epinephrine-to-the-left-ventricle-of-a-severely-anemic-cat-during-cardiopulmonary-resuscitation
#10
Liron Oron, Yaron Bruchim, Sigal Klainbart, Efrat Kelmer
OBJECTIVE: To describe the use of an ultrasound-guided intracardiac xenotransfusion of canine packed red blood cells (pRBC) to the left ventricle of a severely anemic cat during cardiopulmonary resuscitation (CPR). CASE SUMMARY: An 8-year-old previously healthy neutered female cat was presented with severe weakness after she had disappeared for 1 month. On presentation, the cat was in hypovolemic shock, laterally recumbent, and severely anemic with massive flea infestation...
January 10, 2017: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/28065787/intestinal-farnesoid-x-receptor-controls-transintestinal-cholesterol-excretion-in-mice
#11
Jan Freark de Boer, Marleen Schonewille, Marije Boesjes, Henk Wolters, Vincent W Bloks, Trijnie Bos, Theo H van Dijk, Angelika Jurdzinski, Renze Boverhof, Justina C Wolters, Jan A Kuivenhoven, Jan M van Deursen, Ronald P J Oude Elferink, Antonio Moschetta, Claus Kremoser, Henkjan J Verkade, Folkert Kuipers, Albert K Groen
BACKGROUND & AIMS: The role of the intestine in the maintenance of cholesterol homeostasis is increasingly recognized. Fecal excretion of cholesterol is the last step in the atheroprotective reverse cholesterol transport pathway, to which biliary and transintestinal cholesterol excretion (TICE) contribute. The mechanisms controlling the flux of cholesterol through the TICE pathway are, however, poorly understood. We aimed to identify mechanisms that regulate and stimulate TICE. METHODS: We performed studies with C57Bl/6J mice, as well as mice with intestine-specific knockout of the farnesoid X receptor (FXR), mice that express an FXR transgene specifically in the intestine, and ABCG8-knockout mice...
January 5, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28060234/reorientational-proximal-femoral-osteotomies-for-arthrogrypotic-hip-contractures
#12
Harold Jacob Pieter van Bosse, Roger E Saldana
BACKGROUND: Severe hip contractures in arthrogrypsosis are multiplanar, which can preclude or can greatly complicate sitting and ambulation. The reorientational osteotomy at the intertrochanteric level preserves preoperative hip motion but moves it to a more functional domain. We retrospectively compared preoperative and postoperative hip motion and evaluated the ambulatory abilities of patients who underwent the procedure. METHODS: Since 2008, 65 patients with arthrogryposis had 119 reorientational proximal femoral osteotomies with a minimum follow-up of 2 years...
January 4, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28057168/evaluation-and-optimization-of-blood-micro-sampling-methods-serial-sampling-in-a-cross-over-design-from-an-individual-mouse
#13
Nita J Patel, Enaksha Wickremsinhe, Yu-Hua Hui, Alexandar Barr, Nicholas Masterson, Kenneth Ruterbories, Jennifer Weller, Jennifer Hanes, Tom Kern, Everett Perkins
PURPOSE: Current practices applied to mouse pharmacokinetic (PK) studies often use large numbers of animals with sporadic or composite sampling that inadequately describe PK profiles.  The purpose of this work was to evaluate and optimize blood microsampling techniques coupled with dried blood spot (DBS) and LC-MS/MS analysis to generate reliable PK data in mice.  In addition, the feasibility of cross-over designs was assessed and recommendations are presented. METHODS: The work describes a comprehensive evaluation of five blood microsampling techniques (tail clip, tail vein with needle hub, submandibular, retro-orbital, and saphenous bleeding) in CD-1 mice...
October 2016: Journal of Pharmacy & Pharmaceutical Sciences: a Publication of the Canadian Society for Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28052289/the-pharmacokinetic-interaction-study-between-carvedilol-and-bupropion-in-rats
#14
Maria Bianca Abrudan, Dana Maria Muntean, Ana Maria Gheldiu, Maria Adriana Neag, Laurian Vlase
BACKGROUND/AIMS: The effects of multiple-dose bupropion on the pharmacokinetics of single-dose carvedilol were investigated in order to evaluate this possible drug-drug interaction. METHODS: A preclinical study was conducted among white male Wistar rats. Each rat was cannulated on the femoral vein prior to being connected to BASi Culex ABC®. During the reference period, each rat received an intravenous and an oral dose of 3.57 mg/kg body weight (b.w.) carvedilol, at 2 days distance...
January 5, 2017: Pharmacology
https://www.readbyqxmd.com/read/28041770/individualised-expert-feedback-is-not-essential-for-improving-basic-clinical-skills-performance-in-novice-learners-a-randomized-trial
#15
Alexander W Phillips, Joanna Matthan, Lucy R Bookless, Ian J Whitehead, Anantha Madhavan, Paul Rodham, Anna L R Porter, Craig I Nesbitt, Gerard Stansby
OBJECTIVE: To determine whether unsupervised video feedback (UVF) is as effective as direct expert feedback (DEF) in improving clinical skills performance for medical students learning basic surgical skills-intravenous cannulation, catheterization, and suturing. BACKGROUND: Feedback is a vital component of the learning process, yet great variation persists in its quality, quantity, and methods of delivery. The use of video technology to assist in the provision of feedback has been adopted increasingly...
December 29, 2016: Journal of Surgical Education
https://www.readbyqxmd.com/read/28034694/single-jugular-vein-cannulated-rats-may-not-be-suitable-for-intravenous-pharmacokinetic-screening-of-high-logp-compounds
#16
Nilesh Gaud, Anoop Kumar, Muralikrishna Matta, Prashant Kole, Srikanth Sridhar, Sandhya Mandlekar, Vinay K Holenarsipur
Rat is commonly used for pharmacokinetic screening during pharmaceutical lead optimization. To handle the large number of compounds, rats with a single jugular vein cannulation are commonly utilized for intravenous pharmacokinetic studies, where the same cannula is used both for dose administration and blood sampling. We demonstrate that the single cannula method is not suitable for all compounds, especially for high logP compounds. We propose an alternative dual cannulation technique in which two cannulas are placed in the same jugular vein, thus avoiding an additional surgery...
March 1, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28032329/pain-prevalence-in-hospitalized-children-a-prospective-cross-sectional-survey-in-four-danish-university-hospitals
#17
S Walther-Larsen, M T Pedersen, S M Friis, G B Aagaard, J Rømsing, E M Jeppesen, S J Friedrichsdorf
BACKGROUND: Pain management in hospitalized children is often inadequate. The prevalence and main sources of pain in Danish university hospitals is unknown. METHODS: This prospective mixed-method cross-sectional survey took place at four university hospitals in Denmark. We enrolled 570 pediatric patients who we asked to report their pain experience and its management during the previous 24 hours. For patients identified as having moderate to severe pain, patient characteristics and analgesia regimes were reviewed...
March 2017: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/27999461/radial-artery-pseudoaneurysm-with-aberrant-radial-artery-anatomy-an-unusual-presentation-of-flexor-tenosynovitis
#18
Nicholas A Calotta, Megan E Gornet, Edward F McCarthy, Donna Magid, E Gene Deune
Purpose Radial artery pseudoaneurysm is uncommon and mainly associated with radial artery cannulization for cardiac intervention or invasive hemodynamic monitoring. It is rarely seen as a result of intra-arterial recreational drug injection. Methods We present the case of a 35-year-old man with a 12-year history of intravenous drug use and 1-year history of intra-arterial drug use who developed radial artery pseudoaneurysm with a right long finger suppurative flexor tenosynovitis and subsequent acute radial-sided hand ischemia...
December 2016: Journal of Hand and Microsurgery
https://www.readbyqxmd.com/read/27995028/cost-effectiveness-analysis-of-ultrasound-guided-seldinger-peripherally-inserted-central-catheters-picc
#19
Jianghong Tan, Liping Liu, Jing Xie, Lingli Hu, Qiaolan Yang, Honghong Wang
BACKGROUND: Ultrasound-guided cannulation of deep mid-arm veins by a modified Seldinger (US-Seldinger) technique has been demonstrated to yield better puncture success rates and lower postoperative complication rates than direct cannulation of superficial veins near the elbow with a short peripheral cannula and peripherally inserted central catheter (PICC) insertion through the cannula (non-US conventional method). Economic factors have been evaluated across different operators (i.e. nurses, radiologists, and general practitioners) and different venous catheter types (i...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27990430/metformin-prevents-nonunion-after-three-cannulated-screw-fixation-in-displaced-femoral-neck-fractures-a-retrospective-study
#20
Xiao-Zhong Zhu, Xian-You Zheng
Patients aged from 40 to 60 with displaced fractures of the femoral neck (Garden III or IV) who received fixation with three cannulated screws from January 2005 to December 2012 were evaluated retrospectively for the development of nonunion. Plasma HbA1C, a marker for long-term plasma glucose level, anti-T2DM medication, and other potential risk factors were recorded for the purpose of this study. There were no differences between the union and nonunion groups with respect to age, gender, Garden classification, Pauwel's angle, reduction quality, and T2DM presence...
2016: BioMed Research International
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