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https://www.readbyqxmd.com/read/28430896/evidence-of-secular-trend-in-mandibular-pubertal-growth
#1
Raphael Patcas, Daniel B Wiedemeier, Goran Markic, Philipp Beit, Heidi Keller
Background: During puberty, mandibular growth follows a growth curve comparable to somatic growth. This study aimed to review the relationship between mandibular pubertal peak height velocity (PHV) and skeletal age, and to investigate the possibility of a secular trend. Methods: Retrospective analysis was performed of two historical craniofacial growth studies (Denver Growth Study; observational time: 1943-1965, and Zurich Growth Study; observational time: 1982-1984) of healthy untreated subjects...
April 20, 2017: European Journal of Orthodontics
https://www.readbyqxmd.com/read/28426767/benign-metastasizing-leiomyoma-a-review-of-current-literature-in-respect-to-the-time-and-type-of-previous-gynecological-surgery
#2
Edyta Barnaś, Mariusz Książek, Renata Raś, Andrzej Skręt, Joanna Skręt-Magierło, Ewa Dmoch-Gajzlerska
INTRODUCTION: Benign metastasizing leiomyoma (BML) is a rare disorder that affects women with a history of uterine leiomyoma, which is found to metastasise within extrauterine sites. The aetiology of BML remains unexplained. Because BML is rare, and most publications contain descriptions of single cases, no statistically determined time relations were found between the primary and secondary surgeries, which may have aetiological implications. OBJECTIVES: To determine age before BML surgery, age during diagnosis of BML, type of prior surgery, and location of metastasis based on the literature...
2017: PloS One
https://www.readbyqxmd.com/read/28426310/a-public-health-approach-to-hepatitis-c-in-an-urban-setting
#3
Fabienne Laraque, Jay K Varma
The clinical consequences of HCV infection are increasing because the population with the highest prevalence of the infection, persons born between 1945 and 1965, is aging. As a result, health care expenditures are expected to increase. Now that a cure for HCV infection is the norm, a public health approach is necessary to identify, link to care, and treat infected persons and prevent new infections. We believe that the success of public health interventions, such as those for tuberculosis, can be translated to HCV infection...
April 20, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28421707/content-analysis-of-the-professional-journal-of-the-royal-college-of-speech-and-language-therapists-iii-1966-2015-into-the-21st-century
#4
Linda Armstrong, Jois Stansfield, Steven Bloch
BACKGROUND: Following content analyses of the first 30 years of the UK speech and language therapy professional body's journal, this study was conducted to survey the published work of the speech (and language) therapy profession over the last 50 years and trace key changes and themes. AIM: To understand better the development of the UK speech and language therapy profession over the last 50 years. METHODS & PROCEDURES: All volumes of the professional journal of the Royal College of Speech and Language Therapists published between 1966 and 2015 (British Journal of Communication Disorders, European Journal of Communication Disorders and International Journal of Language and Communication Disorders) were examined using content analysis...
April 18, 2017: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/28414407/medical-student-teaching-and-recruiting-50-years-of-balancing-two-educational-aims
#5
Benjamin N Schneider, Alexander Chessman, William Toffler, Lara Handler, Beat Steiner, Frances Emily Biagioli
Family medicine (FM) undergraduate medical educators have had two distinct missions, to increase the knowledge, skills, and attitudes of all students while also striving to attract students to the field of family medicine. A five decade literature search was conducted gathering FM curricular innovations and the parallel trends in FM medical student interest. Student interest in FM had a rapid first-decade rise to 14%, a second 1990's surge, followed by a drop to the current plateau of 8-9%. This falls far short of the 30-50% generalist benchmark needed to fill the country's health care needs...
April 2017: Family Medicine
https://www.readbyqxmd.com/read/28406430/palliative-care-and-the-family-caregiver-trading-mutual-pretense-empathy-for-a-sustained-gaze-compassion
#6
Joy Goldsmith, Sandra L Ragan
In this conceptual piece, we survey the progress of palliative care communication and reflect back on a chapter we wrote a decade ago, which featured the communication concept of mutual pretense, first described by Glaser and Strauss (1965). This work will include an update on family caregivers and their role in cancer caregiving as well as a review of current palliative care communication curriculum available for providers. And finally, we will spotlight the conversation and research going forward on the subject of health literacy for all stakeholders; patients, families, providers, and systems...
April 13, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/28401165/evaluation-of-mobile-phone-and-cordless-phone-use-and-glioma-risk-using-the-bradford-hill-viewpoints-from-1965-on-association-or-causation
#7
REVIEW
Michael Carlberg, Lennart Hardell
Objective. Bradford Hill's viewpoints from 1965 on association or causation were used on glioma risk and use of mobile or cordless phones. Methods. All nine viewpoints were evaluated based on epidemiology and laboratory studies. Results. Strength: meta-analysis of case-control studies gave odds ratio (OR) = 1.90, 95% confidence interval (CI) = 1.31-2.76 with highest cumulative exposure. Consistency: the risk increased with latency, meta-analysis gave in the 10+ years' latency group OR = 1.62, 95% CI = 1.20-2...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28397699/restrictive-versus-liberal-blood-transfusion-for-gastrointestinal-bleeding-a-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#8
Ayodele Odutayo, Michael J R Desborough, Marialena Trivella, Adrian J Stanley, Carolyn Dorée, Gary S Collins, Sally Hopewell, Susan J Brunskill, Brennan C Kahan, Richard F A Logan, Alan N Barkun, Michael F Murphy, Vipul Jairath
BACKGROUND: Acute upper gastrointestinal bleeding is a leading indication for red blood cell (RBC) transfusion worldwide, although optimal thresholds for transfusion are debated. METHODS: We searched MEDLINE, Embase, CENTRAL, CINAHL, and the Transfusion Evidence Library from inception to Oct 20, 2016, for randomised controlled trials comparing restrictive and liberal RBC transfusion strategies for acute upper gastrointestinal bleeding. Main outcomes were mortality, rebleeding, ischaemic events, and mean RBC transfusion...
May 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28390294/season-of-birth-and-schizophrenia-evidence-from-china
#9
Cuntong Wang, Yudong Zhang
Controversies exist whether season of birth is associated with schizophrenia development later in life, and evidence has mainly come from studies done in developed countries. This study examines the association between season of birth and risk for schizophrenia in China, with special attention to geographical region, urbanity, and gender. Using data from China's Second National Sampling Survey on Disability, a large-scale, nationally representative sample (N=2,052,694), this study employs discrete-time hazard models to compare the risk for schizophrenia development for people born in different seasons, and conducts subsample analyses by geographical region, urbanity, and gender...
March 28, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28387172/review-of-surgical-techniques-of-experimental-renal-transplantation-in-rats
#10
Badri Shrestha, John Haylor
Microvascular surgical techniques of renal transplant in rats have evolved over the past 5 decades to achieve successful rat renal transplant; these modifications have included surgical techniques to address the anatomic variations in the renal blood vessels and those to reduce ischemic and operation durations. Here, we review the surgical techniques of renal transplant in rats and evaluate the advantages and disadvantages of individual techniques of vascular and ureteric anastomoses. For this review, we performed a systematic literature search using relevant medical subject heading terms and included appropriate publications in the review...
April 6, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28384904/indian-soldiers-need-eye-protection
#11
REVIEW
Kirti Nath Jha
Combat-related eye injuries entail enormous financial, social and psychological cost. Military Combat Eye Protection (MCEP) decreases both the incidence and severity of eye injuries. Experts have recognised the need for MCEP for Indian soldiers. We aim to review the combat-related eye injuries and combat eye protection among the Indian soldiers. Global practices of MCEP are also reviewed. We also aim to offer our recommendations for Indian soldiers. We carried out Medline search for combat-related eye injuries and MCEP and separately searched for eye injuries among Indian soldiers during war and other operations...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28384791/association-of-surgical-treatment-systemic-therapy-and-survival-in-patients-with-abdominal-visceral-melanoma-metastases-1965-2014-relevance-of-surgical-cure-in-the-era-of-modern-systemic-therapy
#12
Gary B Deutsch, Devin C Flaherty, Daniel D Kirchoff, Mariel Bailey, Sarah Vitug, Leland J Foshag, Mark B Faries, Anton J Bilchik
Importance: Systemic therapy for metastatic melanoma has evolved rapidly during the last decade, and patient treatment has become more complex. Objective: To evaluate the survival benefit achieved through surgical resection of melanoma metastatic to the abdominal viscera in patients treated in the modern treatment environment. Design, Setting, and Participants: This retrospective review of the institutional melanoma database from the John Wayne Cancer Institute at Providence St Johns Health Center, a tertiary-level melanoma referral center, included 1623 patients with melanoma diagnosed as having potentially resectable abdominal metastases before (1969-2003) and after (2004-2014) advances in systemic therapy...
April 5, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28384078/risk-of-second-cancer-in-hodgkin-lymphoma-survivors-and-influence-of-family-history
#13
Amit Sud, Hauke Thomsen, Kristina Sundquist, Richard S Houlston, Kari Hemminki
Purpose Although advances in Hodgkin lymphoma (HL) treatment have led to improved disease-free survival, this has been accompanied by an increased risk of second cancers. We sought to quantify the second cancer risks and to investigate the impact of family history. Patients and Methods Using the Swedish Family-Cancer Project Database, we identified 9,522 individuals with primary HL diagnosed between 1965 and 2012. We calculated standardized incidence ratios and cumulative incidence of second cancer in HL survivors and compared the standardized incidence ratios of lung, breast, colorectal, and all second cancers in HL survivors with and without a site-specific family history of cancer...
March 13, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28379594/pyrrolizidine-alkaloids-enhance-alcohol-induced-hepatocytotoxicity-in-vitro-in-normal-human-hepatocytes
#14
M G Neuman, L B Cohen, V Steenkamp
OBJECTIVE: Herbal remedies containing pyrrilidozine alkaloids (PA)s can induce liver damage, including hepato-sinusoidal obstruction syndrome (HSOS) or veno-occlusive liver disease (VOD). Some individuals misusing alcohol consume also teas and/or herbal remedies containing PA. The interaction or additive toxicity of alcohol to PA toxicity needs to be addressed. The objectives of this study are 1) to review the scientific literature on the PA-induced liver toxicity; 2) identify possible mechanism(s) involved in PA-induced hepatocytotoxicity in the presence or absence of ethanol (EtOH) in vitro in normal human hepatocytes (NHH) in primary culture...
March 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28373042/-enterovirus-infection-during-pregnancy-underestimated-cause-of-fetal-and-neonatal-complications
#15
J Méreaux, O Picone, C Vauloup-Fellous, Z Khediri, A Benachi, L Mandelbrot, J-M Ayoubi
Enteroviruses are responsible for about one billion infections every year in the world. The clinical expression is in the vast majority asymptomatic cases (90%). Its consequences during pregnancy are rarely described. From the Medline database, we selected and analyzed 34 articles ranging from 1965 to 2015, to analyse the current knowledge of enterovirus infection consequences during pregnancy. We found that enterovirus infections may be the cause of fetal loss. The enterovirus infections during the 2nd and 3rd trimester may also lead to in utero fetal anomalies and death, but also to severe neonatal infections...
March 31, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/28346375/liposomal-formulations-in-clinical-use-an-updated-review
#16
REVIEW
Upendra Bulbake, Sindhu Doppalapudi, Nagavendra Kommineni, Wahid Khan
Liposomes are the first nano drug delivery systems that have been successfully translated into real-time clinical applications. These closed bilayer phospholipid vesicles have witnessed many technical advances in recent years since their first development in 1965. Delivery of therapeutics by liposomes alters their biodistribution profile, which further enhances the therapeutic index of various drugs. Extensive research is being carried out using these nano drug delivery systems in diverse areas including the delivery of anti-cancer, anti-fungal, anti-inflammatory drugs and therapeutic genes...
March 27, 2017: Pharmaceutics
https://www.readbyqxmd.com/read/28345789/childhood-body-mass-index-and-development-of-type-2-diabetes-throughout-adult-life-a-large-scale-danish-cohort-study
#17
Esther Zimmermann, Lise G Bjerregaard, Michael Gamborg, Allan A Vaag, Thorkild I A Sørensen, Jennifer L Baker
OBJECTIVE: This study investigated how a wide spectrum of body mass index (BMI) values at ages 7 to 13 years are associated with type 2 diabetes throughout adulthood, including potential modifying effects of sex and birth weight. METHODS: From the Copenhagen School Health Records Register, 292,827 individuals, born between 1930 and 1989, were followed in national registers for type 2 diabetes (women, n = 7,472; men, n = 11,548). Heights and weights were measured at ages 7 to 13 years...
March 27, 2017: Obesity
https://www.readbyqxmd.com/read/28341628/species-richness-and-endemism-in-the-native-flora-of-california
#18
Bruce G Baldwin, Andrew H Thornhill, William A Freyman, David D Ackerly, Matthew M Kling, Naia Morueta-Holme, Brent D Mishler
PREMISE OF THE STUDY: California's vascular flora is the most diverse and threatened in temperate North America. Previous studies of spatial patterns of Californian plant diversity have been limited by traditional metrics, non-uniform geographic units, and distributional data derived from floristic descriptions for only a subset of species. METHODS: We revisited patterns of sampling intensity, species richness, and relative endemism in California based on equal-area spatial units, the full vascular flora, and specimen-based distributional data...
March 24, 2017: American Journal of Botany
https://www.readbyqxmd.com/read/28339427/a-critical-analysis-of-obamacare-affordable-care-or-insurance-for-many-and-coverage-for-few
#19
Laxmaiah Manchikanti, Standiford Helm Ii, Ramsin M Benyamin, Joshua A Hirsch
The Affordable Care Act (ACA), of 2010, or Obamacare, was the most monumental change in US health care policy since the passage of Medicaid and Medicare in 1965. Since its enactment, numerous claims have been made on both sides of the aisle regarding the ACA's success or failure; these views often colored by political persuasion. The ACA had 3 primary goals: increasing the number of the insured, improving the quality of care, and reducing the costs of health care. One point often lost in the discussion is the distinction between affordability and access...
March 2017: Pain Physician
https://www.readbyqxmd.com/read/28339426/evolution-of-us-health-care-reform
#20
Laxmaiah Manchikanti, Standiford Helm Ii, Ramsin M Benyamin, Joshua A Hirsch
Major health policy creation or changes, including governmental and private policies affecting health care delivery are based on health care reform(s). Health care reform has been a global issue over the years and the United States has seen proposals for multiple reforms over the years. A successful, health care proposal in the United States with involvement of the federal government was the short-lived establishment of the first system of national medical care in the South. In the 20th century, the United States was influenced by progressivism leading to the initiation of efforts to achieve universal coverage, supported by a Republican presidential candidate, Theodore Roosevelt...
March 2017: Pain Physician
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