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https://www.readbyqxmd.com/read/28913613/risk-factor-analysis-between-newly-screened-and-established-hepatitis-c-in-gi-and-hepatology-clinics
#1
Newaz Hossain, Bharat Puchakayala, Pushpjeet Kanwar, Siddharth Verma, George Abraham, Zhanna Ivanov, Muhammad Obaid Niaz, Smruti R Mohanty
BACKGROUND: Several studies show inconsistencies in the rate of hepatitis C virus (HCV) detection among baby boomers (born 1945-1965). We conducted a cross-sectional HCV screening followed by a case-controlled comparison of the newly screened population with established HCV subjects. METHOD: Enrollment was offered to subjects aged 40-75 at our gastroenterology and hepatology clinics. Demographic data and potential risk factors were obtained, and HCV antibody test was offered to those who had never been screened and compared with a group with established HCV...
September 14, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28893101/improving-hepatitis-c-identification-technology-alone-is-not-the-answer
#2
Bruce Nitsche, Sara C Miller, Margaret Giorgio, Carolyn A Berry, Andrew Muir
An estimated 3 to 5 million Americans are chronically infected with hepatitis C virus (HCV), and approximately 75% of those persons were born between 1945 and 1965 (the so-called baby boomer generation). Because of the largely asymptomatic nature of HCV, up to 50% of those infected are unaware of their disease. Risk-based testing has been largely ineffective. Based on prevalence data, the Centers for Disease Control and Prevention and other organizations recommend a onetime HCV antibody test for all baby boomers...
September 1, 2017: Health Promotion Practice
https://www.readbyqxmd.com/read/28887343/population-health-and-medicine-policy-and-financial-drivers
#3
Jill E Lavigne, Jack Brown, Gary R Matzke
PURPOSE: The financial and policy levers of population health and potential opportunities for pharmacists are described. SUMMARY: Three long-standing problems drive the focus on population health: (1) the United States suffers far worse population health outcomes compared with those of other developed nations that spend significantly less on healthcare, (2) the U.S. healthcare system's focus on "sick care" fails to address upstream prevention and population health improvement, and (3) financial incentives for healthcare delivery are poorly aligned with improvements in population health outcomes...
September 15, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28882516/genetic-characterization-of-the-glycoprotein-g-of-chandipura-viruses-in-india-with-emphasis-on-an-outbreak-of-2015
#4
R G Damle, V Sankararaman, V S Bhide, S A Mahamuni, A M Walimbe, S S Cherian
Chandipura virus (CHPV) is found to be associated with sporadic encephalitis outbreaks in humans in India since 1965. We report here, the investigation of CHPV activity during the period of June-August 2015 in the state of Gujarat, which revealed 24.44% positivity among 45 referred encephalitis cases. Phylogenetic study of the G gene sequences of strains from Gujarat 2015 along with available sequences of additional strains from different geographical locations and isolation years (1965-2015), indicated the relatedness of the 2015 strain to a group of the CHPV prototype strain of 1965 and the earliest outbreak strains of 2003...
September 4, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28880893/trends-in-summer-bottom-water-temperatures-on-the-northern-gulf-of-mexico-continental-shelf-from-1985-to-2015
#5
R Eugene Turner, Nancy N Rabalais, Dubravko Justić
We quantified trends in the 1985 to 2015 summer bottom-water temperature on the northern Gulf of Mexico (nGOM) continental shelf for data collected at 88 stations with depths ranging from 3 to 63 m. The analysis was supplemented with monthly data collected from 1963 to 1965 in the same area. The seasonal summer peak in average bottom-water temperature varied concurrently with air temperature, but with a 2- to 5-month lag. The summer bottom-water temperature declined gradually with depth from 30 oC at stations closest to the shore, to 20 oC at the offshore edge of the study area, and increased an average 0...
2017: PloS One
https://www.readbyqxmd.com/read/28880760/diabetes-and-pressure-ulcer-risk-in-hip-fracture-patients-a-meta-analysis
#6
R Wei, H-L Chen, M-Li Zha, Z-Y Zhou
OBJECTIVE: The aim of this study was to assess the relationship between diabetes and pressure ulcer (PU) risk in patients with hip fractures. METHOD: Searches of MEDLINE (1966-), ISI Databases (1965-) and Scopus (1996-) were performed for English language studies. The search data was 29 July 2016. Odds ratio (OR) for PUs were calculated for hip fracture patients with or without diabetes and a meta-analysis was carried out following meta-analysis of observational studies in epidemiology (MOOSE) guidelines...
September 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28872267/psychological-pain-in-suicidality-a-meta-analysis
#7
Déborah Ducasse, Ronald R Holden, Laurent Boyer, Sylvaine Artéro, Raffaella Calati, Sébastien Guillaume, Philippe Courtet, Emilie Olié
OBJECTIVE: Perform a meta-analysis to quantify the association between psychological pain and current or lifetime history of suicidal ideation or suicide attempt. DATA SOURCES: Search MEDLINE, Web of Science, and PsycINFO from 1965 to 2015 for (psychache OR mental pain OR psychological pain) AND (suicid*). STUDY SELECTION: Observational case-control studies addressing the difference in psychological pain between individuals with and without current or lifetime history of suicidal ideation or suicide attempt...
August 29, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28864710/principles-of-child-health-care-financing
#8
Mark L Hudak, Mark E Helm, Patience H White
After passage of the Patient Protection and Affordable Care Act, more children and young adults have become insured and have benefited from health care coverage than at any time since the creation of the Medicaid program in 1965. From 2009 to 2015, the uninsurance rate for children younger than 19 years fell from 9.7% to 5.3%, whereas the uninsurance rate for young adults 19 to 25 years of age declined from 31.7% to 14.5%. Nonetheless, much work remains to be done. The American Academy of Pediatrics (AAP) believes that the United States can and should ensure that all children, adolescents, and young adults from birth through the age of 26 years who reside within its borders have affordable access to high-quality and comprehensive health care, regardless of their or their families' incomes...
September 2017: Pediatrics
https://www.readbyqxmd.com/read/28862800/neurological-and-neurophysiological-findings-in-workers-with-chronic-2-3-7-8-tcdd-intoxication-50-years-after-exposure
#9
Daniela Pelclova, Pavel Urban, Zdenka Fenclova, Stepanka Vlckova, Petr Ridzon, Karel Kupka, Zuzana Meckova, Ondrej Bezdicek, Tomas Navratil, Jan Rosmus, Sergey Zakharov
The last eight survivors of 80 workers accidentally exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) during production of herbicides based on trichlorophenoxyacetic acid in 1965-1967 in a chemical factory were followed. All were men, mean age 72.4 ± 1.3 years. Their current median TCDD blood level was 112 (46-390) pg/g lipids. Neurological examination revealed central nervous system impairment in all subjects, and signs of polyneuropathy in 87.5%, which was confirmed by a nerve conduction study (NCS) in 75%...
September 1, 2017: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28851337/which-online-format-is-most-effective-for-assisting-baby-boomers-to-complete-advance-directives-a-randomised-controlled-trial-of-email-prompting-versus-online-education-module
#10
Sandra L Bradley, Jennifer J Tieman, Richard J Woodman, Paddy A Phillips
BACKGROUND: Completion of Advance Directives (ADs), being financial and healthcare proxy or instructional documents, is relatively uncommon in Australia. Efforts to increase completion rates include online education and prompting which past literature suggests may be effective. The aim of this randomized controlled trial was to assess computer-based online AD information and email prompting for facilitating completion of ADs by Australian Baby Boomers (b.1946-1965) as well as factors which may impede or assist completion of these documents by this generation when using the online environment...
August 29, 2017: BMC Palliative Care
https://www.readbyqxmd.com/read/28833849/fifty-years-of-child-height-and-weight-in-japan-and-south-korea-contrasting-secular-trend-patterns-analyzed-by-sitar
#11
T J Cole, H Mori
Objectives Japanese and South Koreans have traditionally been shorter than Europeans, but have recently become appreciably taller. The aim was to quantify the secular trend patterns in height and weight growth in the two countries over 50 years using the SITAR growth curve model. Methods Data on mean height and weight by sex in 1-year age groups from 1 to 20 years were obtained by decade in South Korea (1965-2005) and Japan (1950-2010). The data were analyzed using SITAR (SuperImposition by Translation And Rotation), which estimates a mean curve and three adjustments-size, timing and intensity-reflecting how the individual surveys differ from the mean...
August 23, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/28833287/changes-in-medical-management-and-colectomy-rates-a-population-based-cohort-study-on-the-epidemiology-and-natural-history-of-ulcerative-colitis-in-%C3%A3-rebro-sweden-1963-2010
#12
C Eriksson, Y Cao, S Rundquist, Y Zhulina, I Henriksson, S Montgomery, J Halfvarson
BACKGROUND: Whether the epidemiology of ulcerative colitis (UC) has changed during recent decades is partly unknown. AIM: To depict temporal trends in the epidemiology and medical treatment of UC as well as the long-term risk of progression in disease extent and colectomy, during 1963-2010. METHODS: Patients were identified by evaluation of all medical records in the archive of the Colitis Clinic, Örebro University Hospital. Comparisons were made between three time periods, 1963-1975, 1976-1990 and 1991-2005...
August 17, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28831193/tuberculosis-cryptococcosis-co-infection-in-china-between-1965-and-2016
#13
Wenjie Fang, Lei Zhang, Jia Liu, David W Denning, Ferry Hagen, Weiwei Jiang, Nan Hong, Shuwen Deng, Xia Lei, Danqi Deng, Wanqing Liao, Jianping Xu, Teun Boekhout, Min Chen, Weihua Pan
Cases of tuberculosis/cryptococcosis co-infection are rapidly increasing in China. However, most studies addressing this co-infection have been published in Chinese journals, and this publication strategy has obscured this disease trend for scientists in other parts of the world. Our investigation found that 62.9% of all co-infection cases worldwide were reported in the Chinese population (n=197) between 1965 and 2016, and 56.3% of these Chinese cases were reported after 2010. Nearly all cases originated from the warm and wet monsoon regions of China...
August 23, 2017: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/28829823/assessing-the-relationship-between-toxicity-and-economic-cost-of-oncological-target-agents-a-systematic-review-of-clinical-trials
#14
Francesca Tartari, Alessandro Conti, Roy Cerqueti
Target agents are peculiar oncological drugs which differ from the traditional therapies in their ability of recognizing specific molecules expressed by tumor cells and microenvironment. Thus, their toxicity is generally lower than that associated to chemotherapy, and they represent nowadays a new standard of care in a number of tumors. This paper deals with the relationship between economic costs and toxicity of target agents. At this aim, a cluster analysis-based exploration of the main features of a large collection of them is carried out, with a specific focus on the variables leading to the identification of their toxicity and related costs...
2017: PloS One
https://www.readbyqxmd.com/read/28828754/elemental-and-carbonaceous-characterization-of-tsp-and-pm10-during-middle-eastern-dust-med-storms-in-ahvaz-southwestern-iran
#15
Abbas Shahsavani, Maryam Yarahmadi, Mostafa Hadei, Mohammad Hossein Sowlat, Kazem Naddafi
Middle Eastern dust (MED) storms carry large amounts of dust particles to the Southern and Western cities of Iran. This study aimed to characterize the elemental and carbonaceous composition of total suspended particles (TSP) and PM10 in Ahvaz, Iran. TSP and PM10 samples were collected using two separate high-volume air samplers. The sampling program was performed according to EPA guidelines and resulted in 72 samples. Twenty-eight elements and two carbonaceous components in TSP and PM10 were measured. Over the entire study period, the mean concentration (SD) of TSP and PM10 was 1548...
August 21, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28817628/effectiveness-of-helicobacter-pylori-eradication-in-the-prevention-of-primary-gastric-cancer-in-healthy-asymptomatic-people-a-systematic-review-and-meta-analysis-comparing-risk-ratio-with-risk-difference
#16
Takeshi Seta, Yoshimitsu Takahashi, Yoshinori Noguchi, Satoru Shikata, Tatsuya Sakai, Kyoko Sakai, Yukitaka Yamashita, Takeo Nakayama
BACKGROUND: Helicobacter pylori infection is strongly associated with gastric cancer occurrence. However, it is unclear whether eradication therapy reduces the risk of gastric cancer occurrence. We evaluated whether H. pylori eradication reduces the risk of primary gastric cancer by using both risk ratio (RR) and risk difference (RD). METHODS: Searches of PubMed, EMBASE, Google scholar, the Cochrane Library, and the Japan Medical Abstracts Society as well as those registered in databases of the Cochrane Central Register of Controlled Trials, metaRegister of Controlled Trials, ClinicalTrials...
2017: PloS One
https://www.readbyqxmd.com/read/28815038/management-of-desmoid-tumours-a-large-national-database-of-familial-adenomatous-patients-shows-a-link-to-colectomy-modalities-and-low-efficacy-of-medical-treatments
#17
T Walter, C Zhenzhen Wang, O Guillaud, E Cotte, A Pasquer, O Vinet, G Poncet, T Ponchon, J-C Saurin
BACKGROUND: Desmoid tumours represent a major complication of familial adenomatous polyposis. Our aims were to study the factors associated with the development of desmoid tumours in familial adenomatous polyposis patients, and to describe presentation and management of desmoid tumours. METHODS AND PATIENTS: We reviewed all patients with familial adenomatous polyposis followed at our institution between 1965-2013, with either identified adenomatous polyposis coli gene mutation, or a personal and family history suggesting adenomatous polyposis coli-related polyposis...
August 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28797323/hepatitis-c-virus-seroprevalence-and-prevalence-of-chronic-infection-in-the-adult-population-in-ireland-a-study-of-residual-sera-april-2014-to-february-2016
#18
Patricia Garvey, Brian O'Grady, Geraldine Franzoni, Maeve Bolger, Katie Irwin Crosby, Jeff Connell, Deirdre Burke, Cillian De Gascun, Lelia Thornton
Robust data on hepatitis C virus (HCV) population prevalence are essential to inform national HCV services. In 2016, we undertook a survey to estimate HCV prevalence among the adult population in Ireland. We used anonymised residual sera available at the National Virus Reference Laboratory. We selected a random sample comprising persons ≥ 18 years with probability proportional to the general population age-sex distribution. Anti-HCV and HCV Ag were determined using the Architect anti-HCV and HCV Ag assays...
July 27, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28790164/north-south-disparities-in-english-mortality1965-2015-longitudinal-population-study
#19
Iain E Buchan, Evangelos Kontopantelis, Matthew Sperrin, Tarani Chandola, Tim Doran
BACKGROUND: Social, economic and health disparities between northern and southern England have persisted despite Government policies to reduce them. We examine long-term trends in premature mortality in northern and southern England across age groups, and whether mortality patterns changed after the 2008-2009 Great Recession. METHODS: Population-wide longitudinal (1965-2015) study of mortality in England's five northernmost versus four southernmost Government Office Regions - halves of overall population...
September 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/28769695/the-collection-of-bathynellacea-specimens-of-mncn-csic-madrid-microscope-slices-and-dna-extract
#20
Ana I Camacho, Beatriz A Dorda, Begoña Sánchez Chillón, Isabel Rey
This is the first published database of a Bathynellacea Chappuis, 1915 collection of slices and DNA extracts. It includes all data of bathynellaceans (Crustacea: Syncarida) collected in the last 48 years (1968 to 2016) on the Iberian Peninsula and Balearic Islands, studied since 1984. It also includes specimens studied across many countries of Europe (Portugal, Romania, France, Italy, Slovenia, Bulgaria, and England), as well as some specimens obtained from samples of North America (Montana, Washington, Alaska and Texas), South America (Brazil, Chile and Argentina), Asia (China, Thailand, Vietnam, Mongolia and India), Africa (Morocco and Chad) and Australia (New South Wales -NSW- and Queensland)...
2017: ZooKeys
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