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https://www.readbyqxmd.com/read/28938516/naturally-occurring-anthocyanin-cyanidin-3-rutinoside-possesses-inherent-vasorelaxant-actions-and-prevents-methylglyoxal-induced-vascular-dysfunction-in-rat-aorta-and-mesenteric-arterial-bed
#1
Thavaree Thilavech, Mahinda Y Abeywardena, Michael Adams, Julie Dallimore, Sirichai Adisakwattana
Cyanidin-3-rutinoside (C3R) possesses anti-oxidant, anti-inflammatory and anti-glycation properties. Methylglyoxal (MG), a highly reactive dicarbonyl aldehyde by-product of glycolysis, is a precursor of advanced glycation end products and contributes to vascular dysfunction, particularly during hyperglycemia. We investigated the possible inherent vasoactivity of C3R, and its effectiveness against MG-induced vascular abnormalities in isolated blood vessel preparations from male Wistar Kyoto rat. C3R induced vasorelaxation concentration-dependently in aortic rings (92% maximum relaxation; EC50: 2...
September 18, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28938190/phytobeds-with-fimbristylis-dichotoma-and-ammannia-baccifera-for-treatment-of-real-textile-effluent-an-in-situ-treatment-anatomical-studies-and-toxicity-evaluation
#2
Suhas K Kadam, Vishal V Chandanshive, Niraj R Rane, Swapnil M Patil, Avinash R Gholave, Rahul V Khandare, Amrut R Bhosale, Byong-Hun Jeon, Sanjay P Govindwar
Fimbristylis dichotoma, Ammannia baccifera and their co-plantation consortium FA independently degraded Methyl Orange, simulated dye mixture and real textile effluent. Wild plants of F. dichotoma and A. baccifera with equal biomass showed 91% and 89% decolorization of Methyl Orange within 60h at a concentration of 50ppm, while 95% dye removal was achieved by consortium FA within 48h. Floating phyto-beds with co-plantation (F. dichotoma and A. baccifera) for the treatment of real textile effluent in a constructed wetland was observed to be more efficient and achieved 79%, 72%, 77%, 66% and 56% reductions in ADMI color value, COD, BOD, TDS and TSS of textile effluent, respectively...
September 19, 2017: Environmental Research
https://www.readbyqxmd.com/read/28937659/assessing-the-allocation-of-special-elderly-nursing-homes-in-tokyo-japan
#3
Ninglong You, Zhenjiang Shen, Tatsuya Nishino
Social welfare and public health departments require reliable assessments to enhance the rationality of phased construction of special elderly nursing homes (SENHs). This paper aims to assess the allocation of SENHs based on a beds-needed index for SENHs (BNIS). This may help departments determine the priority for approving locations of SENHs more accurately with a limited budget. Traditional assessments in Tokyo use the sphere of welfare, ward, and sphere of daily life as spatial units for estimating beds-to-elderly population ratios...
September 22, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28937638/effects-of-processing-parameters-on-surface-roughness-of-additive-manufactured-ti-6al-4v-via-electron-beam-melting
#4
Pan Wang, Wai Jack Sin, Mui Ling Sharon Nai, Jun Wei
As one of the powder bed fusion additive manufacturing technologies, electron beam melting (EBM) is gaining more and more attention due to its near-net-shape production capacity with low residual stress and good mechanical properties. These characteristics also allow EBM built parts to be used as produced without post-processing. However, the as-built rough surface introduces a detrimental influence on the mechanical properties of metallic alloys. Thereafter, understanding the effects of processing parameters on the part's surface roughness, in turn, becomes critical...
September 22, 2017: Materials
https://www.readbyqxmd.com/read/28937633/predictive-simulation-of-process-windows-for-powder-bed-fusion-additive-manufacturing-influence-of-the-powder-bulk-density
#5
Alexander M Rausch, Vera E Küng, Christoph Pobel, Matthias Markl, Carolin Körner
The resulting properties of parts fabricated by powder bed fusion additive manufacturing processes are determined by their porosity, local composition, and microstructure. The objective of this work is to examine the influence of the stochastic powder bed on the process window for dense parts by means of numerical simulation. The investigations demonstrate the unique capability of simulating macroscopic domains in the range of millimeters with a mesoscopic approach, which resolves the powder bed and the hydrodynamics of the melt pool...
September 22, 2017: Materials
https://www.readbyqxmd.com/read/28937449/persistent-encopresis-enuresis-and-anxiety-in-a-7-year-old-girl
#6
Theodora Nelson, Heekyung Chae, Ran D Anbar, Martin T Stein
Sonia is a 7-year-old old girl who was referred to the Developmental-Behavioral Pediatrics Clinic by the Pediatric Urology Clinic because of persistent wetting and soiling behaviors. Since age 3 years, she has had a history of encopresis (and wetting) for which she has seen gastroenterology and urology specialists. The mother reports that Sonia has accidents almost daily, and she is not upset when sitting in her urine or feces. She dislikes going into the bathroom or sitting on the toilet by herself. She participated in a behavior modification program associated with the pediatric urology clinic, which helps children learn healthy voiding habits and achieve continence...
September 19, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28937265/salvage-radiotherapy-for-locoregionally-recurrent-extrahepatic-bile-ducth-cancer-after-radical-surgery
#7
Eunji Kim, Yi-Jun Kim, Kyubo Kim, Changoon Song, Jae-Sung Kim, Do-Youn Oh, Eun Mi Nam, Eui Kyu Chie
OBJECTIVE: This study evaluated the outcome of salvage radiotherapy for locoregionally recurrent extrahepatic bile duct cancer. METHODS: We performed a retrospective review of 23 extrahepatic bile duct cancer patients who underwent radiotherapy with or without concomitant chemotherapy for isolated locoregional recurrence after radical surgery between August 2001 and September 2013. The median disease-free interval was 11.8 months. Salvage radiotherapy was delivered to the recurrent tumor with or without initial operation bed up to a median dose of 54 Gy (range, 45-60)...
September 13, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28937162/experimentally-validated-mathematical-model-of-analyte-uptake-by-permeation-passive-samplers
#8
F Salim, M Ioannidis, T Górecki
A mathematical model describing the sampling process in a permeation-based passive sampler was developed and evaluated numerically. The model was applied to the Waterloo Membrane Sampler (WMS), which employs a polydimethylsiloxane (PDMS) membrane as a permeation barrier, and an adsorbent as a receiving phase. Samplers of this kind are used for sampling volatile organic compounds (VOC) from air and soil gas. The model predicts the spatio-temporal variation of sorbed and free analyte concentrations within the sampler components (membrane, sorbent bed and dead volume), from which the uptake rate throughout the sampling process can be determined...
September 22, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/28936439/a-case-of-pulmonary-arteriovenous-malformation-role-of-interventional-radiology-in-diagnosis-and-treatment
#9
Pranav Sharma, Puneet Kochar, Salil Sharma, Nishant Gupta, Shuo Li, Kusum Hooda, Yogesh Kumar
Pulmonary arterio-venous malformations (PAVMs) are abnormal pulmonary arteries and pulmonary veins communicating directly without interposition of a capillary bed and about 80-90% of patients with PAVMs eventually may present with hereditary hemorrhagic telangiectasia (HHT), remaining ones are sporadic cases. On the other hand, about 15-35% of HHT patients may present with PAVMs. The PAVMs have a tendency to grow and increase in size over time and various factors like puberty, pregnancy and pulmonary arterial hypertension (PAH) affect growth...
September 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28936143/assessment-of-readiness-of-academic-emergency-departments-in-the-central-region-of-saudi-arabia-to-receive-a-sick-child
#10
Fahad Saleh Alhajjaj, Abdullah Saleh Aldamigh
OBJECTIVE: We sought to assess the readiness of general emergency departments (EDs) in academic hospitals in the central region of the Kingdom of Saudi Arabia (KSA) to manage pediatric patients using an international tool: The American Academy of Pediatrics, American College of Emergency Physicians, and Emergency Nurses Association guidelines, which include facilities, personnel, safety, and other components. METHODS: We assessed eligible centers during multiple visits from January 2016 to May 2016 in which we inspected the EDs and conducted interviews with their respective leadership in which we independently recorded our observations...
July 2017: International Journal of Health Sciences
https://www.readbyqxmd.com/read/28935969/simultaneous-entanglement-swapping-of-multiple-orbital-angular-momentum-states-of-light
#11
Yingwen Zhang, Megan Agnew, Thomas Roger, Filippus S Roux, Thomas Konrad, Daniele Faccio, Jonathan Leach, Andrew Forbes
High-bit-rate long-distance quantum communication is a proposed technology for future communication networks and relies on high-dimensional quantum entanglement as a core resource. While it is known that spatial modes of light provide an avenue for high-dimensional entanglement, the ability to transport such quantum states robustly over long distances remains challenging. To overcome this, entanglement swapping may be used to generate remote quantum correlations between particles that have not interacted; this is the core ingredient of a quantum repeater, akin to repeaters in optical fibre networks...
September 21, 2017: Nature Communications
https://www.readbyqxmd.com/read/28935890/demonstration-and-analysis-of-the-suction-effect-for-pumping-lymph-from-tissue-beds-at-subatmospheric-pressure
#12
Samira Jamalian, Mohammad Jafarnejad, Scott D Zawieja, Christopher D Bertram, Anatoliy A Gashev, David C Zawieja, Michael J Davis, James E Moore
Many tissues exhibit subatmospheric interstitial pressures under normal physiologic conditions. The mechanisms by which the lymphatic system extracts fluid from these tissues against the overall pressure gradient are unknown. We address this important physiologic issue by combining experimental measurements of contractile function and pressure generation with a previously validated mathematical model. We provide definitive evidence for the existence of 'suction pressure' in collecting lymphatic vessels, which manifests as a transient drop in pressure downstream of the inlet valve following contraction...
September 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28935843/efficacy-and-safety-of-subcutaneous-and-intravenous-rituximab-plus-cyclophosphamide-doxorubicin-vincristine-and-prednisone-in-first-line-diffuse-large-b-cell-lymphoma-the-randomized-mabease-study
#13
Pieternella Lugtenburg, Irit Avivi, Henriette Berenschot, Osman Ilhan, Jean Pierre Marolleau, Arnon Nagler, Antonio Rueda, Monica Tani, Mehmet Turgut, Stuart Osborne, Rodney Smith, Michael Pfreundschuh
Intravenous rituximab plus chemotherapy is standard treatment for diffuse large B-cell lymphoma. A subcutaneous formulation of rituximab is expected to simplify and shorten drug preparation and administration, and to reduce treatment burden. MabEase (NCT01649856) examined efficacy, safety and patient satisfaction with subcutaneous rituximab plus chemotherapy in treatment-naïve patients with diffuse large B-cell lymphoma. Patients were randomized 2:1 to subcutaneous rituximab (intravenous 375 mg/m(2) cycle 1; subcutaneous 1,400 mg cycles 2-8) or intravenous rituximab (375 mg/m(2) cycles 1-8) plus cyclophosphamide, doxorubicin, vincristine, and prednisone every 14 or 21 days...
September 21, 2017: Haematologica
https://www.readbyqxmd.com/read/28935816/forces-to-pierce-cuticle-of-tarsi-and-material-properties-determined-by-nanoindentation-the-achilles-heel-of-bed-bugs
#14
Jorge Bustamante, Jason F Panzarino, Timothy J Rupert, Catherine Loudon
The mechanical properties of bed bug (Cimex lectularius L.) tarsi and pretarsi were investigated in order to evaluate their vulnerability to piercing by plant trichomes (sharp microscopic hairs). Nanoindentation was used to measure the force required to insert a sharp probe into the cuticle of these different regions, as well as to determine creep and reduced elastic moduli for the cuticle. Scanning electron microscopy was used to visualize the indents that had been generated by nanoindentation. The force required to insert a cube corner nanoindenter probe into the cuticle was determined for a range of displacements (1 to 9 µm) and strain rates (0...
September 21, 2017: Biology Open
https://www.readbyqxmd.com/read/28934803/two-interesting-cases-of-meralgia-paraesthetica
#15
Christopher David Jones, Luke Guiot, Mark Portelli, Timothy Bullen, Paul Skaife
Meralgia paraesthetica (MP) is a condition originally described by Bernhardt in 1878 and was eventually named by Roth in 1895. It is caused by compression of the lateral femoral cutaneous nerve (LFCN) resulting in varying types of discomfort. Severity of the symptoms can range from mildly uncomfortable to painfully disabling. In this article we discuss 2 patients with a LFCN injury occurring as a result of laparoscopic ventral rectopexy (LVR). The first patient is a 46-year-old female who reported pain and dysesthesia in the left groin and the anterolateral thigh, 2 days post LCR...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28934676/simultaneous-biofiltration-of-btex-and-hg%C3%A2-from-a-petrochemical-waste-stream
#16
Mostafa Leili, Sima Farjadfard, George A Sorial, Bahman Ramavandi
A biofiltration system was developed to treat benzene, toluene, ethylbenzene, and xylene (BTEX) and Hg° vapour from a petrochemical waste stream during overhaul maintenance. The biofilter compost bed was inoculated with a microbial consortium provided by a petrochemical wastewater treatment plant. The effect of the a BTEX concentration (192.6-973.8 g/m(3)h) and empty bed residence time (EBRT) of 20-100 s were studied under the conditions of steady state, transient, shock BTEX-loading, and off-restart. The findings revealed that during a biofilter start-up, an increase in the influent BTEX concentration to around 334...
September 18, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28934675/management-of-turbidity-current-venting-in-reservoirs-under-different-bed-slopes
#17
Sabine Chamoun, Giovanni De Cesare, Anton J Schleiss
The lifetime and efficiency of dams is endangered by the process of sedimentation. To ensure the sustainable use of reservoirs, many sediment management techniques exist, among which venting of turbidity currents. Nevertheless, a number of practical questions remain unanswered due to a lack of systematic investigations. The present research introduces venting and evaluates its performance using an experimental model. In the latter, turbidity currents travel on a smooth bed towards the dam and venting is applied through a rectangular bottom outlet...
September 18, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28934622/should-i-stay-or-should-i-go-how-healthcare-professionals-close-encounters-with-people-with-dementia-in-the-acute-hospital-setting
#18
Rebecca Allwood, Alison Pilnick, Rebecca O'Brien, Sarah Goldberg, Rowan H Harwood, Suzanne Beeke
Around a quarter of hospital beds in the UK are occupied by patients living with dementia (PWD), and communication impairments are common across all types of dementia, often exacerbated by the hospital environment. Unsurprisingly, healthcare professionals (HCPs) report particular challenges in caring for this patient group, whilst trying to recognise and value their personhood as per the underpinning ethos of person-centred care. However, whilst there is a growing body of research that underlines the importance of communication in dementia care, there is far less that actually examines this communication in real time interaction...
September 9, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28934536/glomus-tumor-of-the-sciatic-nerve-an-extraspinal-cause-of-sciatica
#19
Basilia Onyinyechukwu Nwankwo, Robert M Henshaw, Dhruv Kumar
Glomus tumors are small, benign tumors that arise from glomus bodies, structures found normally within the dermis that assist in temperature regulation via their vasoconstrictive response to sympathetic stimuli. Glomus tumors are found typically in the hand and are classically a cause of focal pain and temperature sensitivity. They often present as a small blue lesion seen under the nail bed of a finger or a toe and cause point tenderness. Glomus tumors of peripheral nerves are exceedingly rare and can lead to disability akin to compressive neuropathy when present...
September 21, 2017: Orthopedics
https://www.readbyqxmd.com/read/28934531/feasibility-and-emotional-impact-of-experimentally-extending-sleep-in-short-sleeping-adolescents
#20
Tori R Van Dyk, Nanhua Zhang, Perry A Catlin, Kaylin Cornist, Shealan McAlister, Catharine Whitacre, Dean W Beebe
Study Objectives: Published experimental sleep manipulation protocols for adolescents have been limited to the summer, limiting causal conclusions about how short sleep affects them on school nights, when they are most likely to restrict their sleep. This study assesses the feasibility and emotional impact of a school-night sleep manipulation protocol to test the effects of lengthening sleep in habitually short-sleeping adolescents. Methods: High school students aged 14-18 years who habitually slept 5-7 hours on school nights participated in a 5-week experimental sleep manipulation protocol...
September 1, 2017: Sleep
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