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https://www.readbyqxmd.com/read/28193816/ontogenetic-adaptations-in-the-visual-systems-of-deep-sea-crustaceans
#1
Tamara M Frank
For all visually competent organisms, the driving force behind the adaptation of photoreceptors involves obtaining the best balance of resolution to sensitivity in the prevailing light regime, as an increase in sensitivity often results in a decrease in resolution. A number of marine species have an additional problem to deal with, in that the juvenile stages live in relatively brightly lit shallow (100-200 m depth) waters, whereas the adult stages have daytime depths of more than 600 m, where little downwelling light remains...
April 5, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28120307/performance-of-the-biological-aerated-filter-bioaugmented-by-a-yeast-magnusiomyces-ingens-lh-f1-for-treatment-of-acid-red-b-and-microbial-community-dynamics
#2
Muyang He, Liang Tan, Shuxiang Ning, Li Song, Shengnan Shi
Biological aerated filters (BAFs) were constructed and operated for assessing the effectiveness of bacterial community bioaugmented by a yeast Magnusiomyces ingens LH-F1 for treatment of azo dye Acid Red B (ARB). Dynamics of both bacterial and fungal communities were analyzed through MiSeq sequencing method. The results showed that the bioaugmented BAF displayed obviously better performance for decolorization, COD removal and detoxification of ARB wastewater than the other two which were inoculated with activated sludge (AS) and single M...
February 2017: World Journal of Microbiology & Biotechnology
https://www.readbyqxmd.com/read/28095429/high-rates-of-non-tuberculous-mycobacteria-isolation-in-mozambican-children-with-presumptive-tuberculosis
#3
Elisa López-Varela, Alberto L García-Basteiro, Orvalho J Augusto, Oscar Fraile, Helder Bulo, Tasmiya Ira, Kizito Gondo, Jakko van Ingen, Denise Naniche, Jahit Sacarlal, Pedro L Alonso
INTRODUCTION: Non-tuberculous mycobacteria (NTM) can cause disease which can be clinically and radiologically undistinguishable from tuberculosis (TB), posing a diagnostic and therapeutic challenge in high TB settings. We aim to describe the prevalence of NTM isolation and its clinical characteristics in children from rural Mozambique. METHODS: This study was part of a community TB incidence study in children <3 years of age. Gastric aspirate and induced sputum sampling were performed in all presumptive TB cases and processed for smear testing using fluorochrome staining and LED Microscopy, liquid and solid culture, and molecular identification by GenoType® Mycobacterium CM/AS assays...
2017: PloS One
https://www.readbyqxmd.com/read/28011091/-oral-care-recommendations-for-patients-with-oral-autoimmune-bullous-diseases
#4
V Sobocinski, S-M Dridi, C Bisson, S Jeanne, F Gaultier, C Prost-Squarcioni, P Bernard, F Pascal, B Lefevre, P Weber, C Abasq, S Agbo-Godeau, P Joly, S Ingen-Housz-Oro, S Duvert-Lehembre
BACKGROUND: Autoimmune bullous diseases (AIBD) may cause chronic oral lesions that progress insidiously. AIMS: To provide recommendations for optimal oral-dental management of patients presenting AIBD with oral involvement. PATIENTS AND METHODS: In the absence of scientific studies with high levels of proof, these recommendations have been drawn up at two meetings by a committee of experts on AIBD comprising 7 dermatologists, 1 stomatologist, 1 maxillofacial surgeon, 2 odontologists and 4 parodontologists...
December 20, 2016: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/27995619/idiopathic-linear-iga-bullous-dermatosis-prognostic-factors-based-on-a-case-series-of-72-adults
#5
J Gottlieb, S Ingen-Housz-Oro, M Alexandre, S Grootenboer-Mignot, F Aucouturier, E Sbidian, E Tancrede, P Schneider, E Regnier, C Picard-Dahan, E Begon, C Pauwels, K Cury, S Hüe, C Bernardeschi, N Ortonne, F Caux, P Wolkenstein, O Chosidow, C Prost-Squarcioni
BACKGROUND: Linear IgA bullous dermatosis (LABD) is a clinically and immunologically heterogeneous, subepidermal, autoimmune blistering disease (AIBD), whose long-term evolution is poorly described. OBJECTIVES: To investigate the clinical and immunological characteristics, follow-up and prognostic factors of adult idiopathic LABD. METHODS: This retrospective study, conducted in our AIBD Referral Center, included adults, diagnosed between 1995 and 2012, with idiopathic LABD, defined as pure or predominant IgA deposits by direct immunofluorescence...
December 20, 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/27988586/three-new-species-of-i-claudiella-i-reichardt-amp-vanin-1976-coleoptera-torridincolidae-from-brazil
#6
Cesar João Benetti, Neusa Hamada
The monotypic Neotropical genus Claudiella Reichardt & Vanin, 1976 is currently known only from Brazil (C. ingens Reichardt & Vanin, 1976). We describe here three new species from Brazil, C. jefersoni sp. n., C. jeaneae sp. n. and C. anamariae sp. n., from Roraima, Minas Gerais and Bahia states, respectively, bringing to four the number of species included in Claudiella. These species can be distinguished by different characteristics observed in the legs, mouth parts, metathoracic wings and male genitalia.
December 5, 2016: Zootaxa
https://www.readbyqxmd.com/read/27979924/tumor-suppressors-btg1-and-ikzf1-cooperate-during-mouse-leukemia-development-and-increase-relapse-risk-in-b-cell-precursor-acute-lymphoblastic-leukemia-patients
#7
Blanca Scheijen, Judith M Boer, Rene' Marke, Esther Tijchon, Dorette van Ingen Schenau, Esme' Waanders, Liesbeth van Emst, Laurens T van der Meer, Rob Pieters, Gabriele Escherich, Martin A Horstmann, Edwin Sonneveld, Nicola Venn, Rosemary Sutton, Luciano Dalla-Pozza, Roland P Kuiper, Peter M Hoogerbrugge, Monique L den Boer, Frank N van Leeuwen
Deletions and mutations affecting lymphoid transcription factor IKZF1 (IKAROS) are associated with an increased relapse risk and poor outcome in B-cell precursor acute lymphoblastic leukemia. However, additional genetic events may either enhance or negate the effects of IKZF1 deletions on prognosis. In a large discovery cohort of 533 childhood B-cell precursor acute lymphoblastic leukemia patients, we observed that single copy losses of BTG1 were significantly enriched in IKZF1-deleted B-cell precursor acute lymphoblastic leukemia (P=0...
December 15, 2016: Haematologica
https://www.readbyqxmd.com/read/27933894/chloromethylhalicyclamine-b-a-marine-derived-protein-kinase-ck1%C3%AE-%C3%AE%C2%B5-inhibitor
#8
Germana Esposito, Marie-Lise Bourguet-Kondracki, Linh H Mai, Arlette Longeon, Roberta Teta, Laurent Meijer, Rob Van Soest, Alfonso Mangoni, Valeria Costantino
The halogenated alkaloid chloromethylhalicyclamine B (1), together with the known natural compound halicyclamine B (2), was isolated from the extract of the sponge Acanthostrongylophora ingens. The structure of compound 1 was determined by spectroscopic means, and it was shown that 1 is produced by reaction of 2 with CH2Cl2 used for extraction. Compound 1 was a selective CK1δ/ε inhibitor with an IC50 of 6 μM, while the natural compound 2 was inactive. The absolute configuration of 1 was determined by quantum mechanical calculation of its ECD spectrum, and this also determined the previously unknown absolute configuration of the parent halicyclamine B (2)...
November 23, 2016: Journal of Natural Products
https://www.readbyqxmd.com/read/27909855/conifer-monoterpene-chemistry-during-an-outbreak-enhances-consumption-and-immune-response-of-an-eruptive-folivore
#9
Amy M Trowbridge, M Deane Bowers, Russell K Monson
Changes in the chemical composition of plant defense compounds during herbivory can impact herbivore resource allocation patterns and thereby herbivore survival, growth, and immune response against endoparasitoid infection. Few studies have investigated folivore responses to changes in plant chemistry that occur under outbreak conditions in mature conifer systems. Using data from an earlier observational field study, we carried out laboratory bioassays to test how variation in monoterpenes in piñon pine trees (Pinus edulis, Pinaceae) during an outbreak affects growth, consumption, and immune response of a specialist herbivore, the Southwestern tiger moth (Lophocampa ingens, Arctiidae)...
December 2016: Journal of Chemical Ecology
https://www.readbyqxmd.com/read/27876935/occurrence-morphology-and-molecular-characterisation-of-bopyrid-parasite-epipenaeon-ingens-nobili-1906-isopoda-bopyridae
#10
Kanagasabapathy Sivasubramanian, Samuthirapandian Ravichandran, Ganapathy Rameshkumar, Narayanasamy Veerappan
Epipenaeon ingens occurs most commonly in Southeast Coast of India parasitized the penaeid shrimp. The present study provides the prevalence, morphological and molecular characterisation of E. ingens collected from the host Metapenaeopsis stridulans. In the present study highlights the significance of high prevalence and genetic diversity of E. ingens in M. stridulans. Intra specific analysis also revealed that E. ingens species detected in the present study can be easily distinguished from the other genospecies of bopyrids...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27846606/emergence-and-spread-of-a-human-transmissible-multidrug-resistant-nontuberculous-mycobacterium
#11
Josephine M Bryant, Dorothy M Grogono, Daniela Rodriguez-Rincon, Isobel Everall, Karen P Brown, Pablo Moreno, Deepshikha Verma, Emily Hill, Judith Drijkoningen, Peter Gilligan, Charles R Esther, Peadar G Noone, Olivia Giddings, Scott C Bell, Rachel Thomson, Claire E Wainwright, Chris Coulter, Sushil Pandey, Michelle E Wood, Rebecca E Stockwell, Kay A Ramsay, Laura J Sherrard, Timothy J Kidd, Nassib Jabbour, Graham R Johnson, Luke D Knibbs, Lidia Morawska, Peter D Sly, Andrew Jones, Diana Bilton, Ian Laurenson, Michael Ruddy, Stephen Bourke, Ian C J W Bowler, Stephen J Chapman, Andrew Clayton, Mairi Cullen, Owen Dempsey, Miles Denton, Maya Desai, Richard J Drew, Frank Edenborough, Jason Evans, Jonathan Folb, Thomas Daniels, Helen Humphrey, Barbara Isalska, Søren Jensen-Fangel, Bodil Jönsson, Andrew M Jones, Terese L Katzenstein, Troels Lillebaek, Gordon MacGregor, Sarah Mayell, Michael Millar, Deborah Modha, Edward F Nash, Christopher O'Brien, Deirdre O'Brien, Chandra Ohri, Caroline S Pao, Daniel Peckham, Felicity Perrin, Audrey Perry, Tania Pressler, Laura Prtak, Tavs Qvist, Ali Robb, Helen Rodgers, Kirsten Schaffer, Nadia Shafi, Jakko van Ingen, Martin Walshaw, Danie Watson, Noreen West, Joanna Whitehouse, Charles S Haworth, Simon R Harris, Diane Ordway, Julian Parkhill, R Andres Floto
Lung infections with Mycobacterium abscessus, a species of multidrug-resistant nontuberculous mycobacteria, are emerging as an important global threat to individuals with cystic fibrosis (CF), in whom M. abscessus accelerates inflammatory lung damage, leading to increased morbidity and mortality. Previously, M. abscessus was thought to be independently acquired by susceptible individuals from the environment. However, using whole-genome analysis of a global collection of clinical isolates, we show that the majority of M...
November 11, 2016: Science
https://www.readbyqxmd.com/read/27722764/subcutaneous-panniculitis-like-t-cell-lymphoma-immunosuppressive-drugs-induce-better-response-than-polychemotherapy
#12
David Michonneau, Tony Petrella, Nicolas Ortonne, Saskia Ingen-Housz-Oro, Nathalie Franck, Stéphane Barete, Maxime Battistella, Marie Beylot-Barry, Béatrice Vergier, Marc Maynadié, Christine Bodemer, Olivier Hermine, Martine Bagot, Nicole Brousse, Sylvie Fraitag
Subcutaneous panniculitis-like T cell lymphoma (SPTCL) is a rare condition usually considered as favourable. However, it is not known whether polychemotherapy or immunosuppressive-based therapy is the best approach for treating SPTCL. Using data collected between 2000 and 2012 in France, we analysed clinical, biological and pathological data of 27 patients with SPTCL. Medical history revealed that 40% of patients had been previously diagnosed with an autoimmune disorder and 22% with inflammatory panniculitis...
October 10, 2016: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/27681584/dermatological-emergencies-evolution-from-2008-to-2014-and-perspectives
#13
C Isnard, S Ingen-Housz-Oro, L Fardet, E Matteodo, S Duval, F Hemery, M Khellaf, T-A Duong, O Chosidow, P Wolkenstein
BACKGROUND: Our dermatological department includes a dermatological emergency unit (DEU) whose activity has grown in recent years. OBJECTIVES: An audit to characterize the activity of our DEU and its evolution in terms of medical demographics of the area. METHODS: We collected the following data from administrative services: number of patients consulting each year in the DEU and in the general emergency unit (GEU) of our hospital between 2008 and 2014; daily and seasonal activity of the DEU; occurrence of a second event in the department and proportion of patients from the DEU who were hospitalized and why...
February 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27677580/genome-wide-association-study-for-acute-otitis-media-in-children-identifies-fndc1-as-disease-contributing-gene
#14
Gijs van Ingen, Jin Li, André Goedegebure, Rahul Pandey, Yun Rose Li, Michael E March, Vincent W V Jaddoe, Marina Bakay, Frank D Mentch, Kelly Thomas, Zhi Wei, Xiao Chang, Heather S Hain, André G Uitterlinden, Henriette A Moll, Cornelia M van Duijn, Fernando Rivadeneira, Hein Raat, Robert J Baatenburg de Jong, Patrick M Sleiman, Marc P van der Schroeff, Hakon Hakonarson
Acute otitis media (AOM) is among the most common pediatric diseases, and the most frequent reason for antibiotic treatment in children. Risk of AOM is dependent on environmental and host factors, as well as a significant genetic component. We identify genome-wide significance at a locus on 6q25.3 (rs2932989, Pmeta=2.15 × 10(-09)), and show that the associated variants are correlated with the methylation status of the FNDC1 gene (cg05678571, P=1.43 × 10(-06)), and further show it is an eQTL for FNDC1 (P=9...
September 28, 2016: Nature Communications
https://www.readbyqxmd.com/read/27673675/vascular-consequences-of-interruption-of-tnf-inhibitor-therapy-in-patients-with-rheumatoid-arthritis
#15
G A Rongen, I Van Ingen, T L Jansen
No abstract text is available yet for this article.
October 6, 2016: Clinical Therapeutics
https://www.readbyqxmd.com/read/27633611/cold-associated-perniosis-of-the-thighs-histopathologically-mimicking-lupus-six-observations
#16
R Karkouche, C Bernigaud, J Fontugne, O Zehou, G Bellaud, M N'Diaye, K Cherif, P Wolkenstein, O Chosidow, N Ortonne, S Ingen-Housz-Oro
BACKGROUND: Equestrian cold panniculitis has been described since 1980 in horse riders or in stable employees. Histological aspect is underdescribed. PATIENTS AND METHODS: We describe clinical and histological features of six horse riding or stable employees patients presenting with upper lateral thigh lesions during the winter months between 2014 and 2016 in our dermatological department. RESULTS: Six horse riding or stable employees ladies without any known disease presented with similar symptoms...
September 16, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27609502/performance-of-a-bedside-test-for-tetanus-immunity-results-of-a-cross-sectional-study-among-three-eds-in-the-netherlands-in-2012-2013
#17
N At van der Maas, R Donken, M J M Te Wierik, C M Swaan, S J M Hahne, H E de Melker
INTRODUCTION: Despite sustained high vaccination coverage and a national guideline by the Health Council (HC-guideline) on tetanus postexposure prophylaxis (T-PEP), tetanus sporadically occurs in the Netherlands. This study aims to assess the added value of a bedside test for tetanus immunity (Tetanos Quick Stick (TQS); Ingen BioSciences Group, France), in the context of routine T-PEP in two adult cohorts: those born before introduction of tetanus toxoid vaccination in the National Immunization Programme (NIP) in 1957 (pre-NIP-cohort; n=196) and those born after (NIP-cohort; n=405)...
September 8, 2016: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/27588456/ingenine-e-a-new-cytotoxic-%C3%AE-carboline-alkaloid-from-the-indonesian-sponge-acanthostrongylophora-ingens
#18
Sabrin R M Ibrahim, Gamal A Mohamed
A new β-carboline alkaloid ingenine E (4), along with three known metabolites annomontine (1), acanthomine A (2), and 1,2,3,4-tetrahydronorharman-1-one (3) were isolated from the Indonesian marine sponge Acanthostrongylophora ingens. Their structure characterization was unequivocally carried out using one- and two-dimensional NMR spectroscopy, as well as high-resolution mass spectrometry. The cytotoxic activity of the isolated compounds was evaluated toward MCF7, A549, HCT116, PC12, and Hela cancer cell lines...
September 2, 2016: Journal of Asian Natural Products Research
https://www.readbyqxmd.com/read/27557835/-my-body-was-my-temple-a-narrative-revealing-body-image-experiences-following-treatment-of-a-spinal-cord-injury
#19
K Alysse Bailey, Kimberley L Gammage, Cathy van Ingen, David S Ditor
PURPOSE: This narrative explores the lived experience of a young woman, Rebecca, and her transitioned body image after sustaining and being treated for a spinal cord injury. METHOD: Data were collected from a single semi-structured in-depth interview. RESULTS: Rebecca disclosed her transitioned body image experiences after sustaining a spinal cord injury and being treated by medical staff immediately following her injury. Before her injury, she described a holistic body experience and named this experience her "temple"...
August 24, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27501844/macracanthorhynchus-ingens-infection-in-an-18-month-old-child-in-florida-a-case-report-and-review-of-acanthocephaliasis-in-humans
#20
Blaine A Mathison, Henry S Bishop, Chad R Sanborn, Samaly Dos Santos Souza, Richard Bradbury
A case of acanthocephaliasis in an 18-month-old child caused by Macracanthorhynchus ingens is reported from Florida. This represents only the third documented case of this species in a human host. An overview of human cases of acanthocephaliasis in the literature is presented, along with a review of the biology, clinical manifestations and pathology in the human host, morphology, and diagnosis.
November 15, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
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