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https://www.readbyqxmd.com/read/27921002/intention-for-cesarean-section-versus-vaginal-delivery-among-pregnant-women-in-isfahan-correlates-and-determinants
#1
Zahra Shams-Ghahfarokhi, Farideh Khalajabadi-Farahani
BACKGROUND: Iran has the second highest rate of cesarean section in the world. the corresponding rate in the third metropolitan city of Iran, Isfahan, is even higher. This paper aimed to assess correlates and determinants of intention for cesarean section versus normal vaginal delivery (NVD) among pregnant women in Isfahan. METHODS: A study was conducted among 400 pregnant women aged 18-38 years, with gestational age of 24-40 weeks who attended labor clinics of nine hospitals in Isfahan during June and July 2014...
October 2016: Journal of Reproduction & Infertility
https://www.readbyqxmd.com/read/27915316/lack-of-screening-underlies-most-stage-5-retinopathy-of-prematurity-among-cases-presenting-to-a-tertiary-eye-center-in-india
#2
Rajvardhan Azad, Parijat Chandra, Anil Gangwe, Vivek Kumar
OBJECTIVE: To study the barriers to effective screening, early detection and treatment of Retinopathy of Prematurity leading to advanced disease. DESIGN: Cross-sectional study. SETTING: Tertiary eye care hospital in northern India. PARTICIPANTS: 115 babies with bilateral stage 5 ROP identified amongst 354 preterm infants examined over a one year period. METHODS: Information regarding gestational age, birthweight, duration of stay in nursery, duration of supplemental oxygen therapy and treatment details were obtained from discharge summary when available, and by interviewing carers...
November 7, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/27914273/quality-of-attachment-in-infants-less-than-1500g-or-less-than-32weeks-related-factors
#3
María López-Maestro, Purificación Sierra-Garcia, Celia Diaz-Gonzalez, Ma Jose Torres-Valdivieso, David Lora-Pablos, Susana Ares-Segura, Carmen R Pallás-Alonso
BACKGROUND: Prematurity carries a high risk of mortality and sequelae, altering the bonding process and leading to repercussions in terms of attachment. OBJECTIVE: To assess the type of attachment in children under 32weeks' gestational age (GA) or below 1500g, in hospitals where development-centred care has been implemented and to study the association between various types of attachment and certain neonatal and family characteristics. METHOD: Children <1500g or <32weeks GA who were born or admitted before 48h of life to one of two hospitals in Madrid between January and December 2012 were candidates for the study...
November 30, 2016: Early Human Development
https://www.readbyqxmd.com/read/27893896/association-between-influenza-infection-and-vaccination-during-pregnancy-and-risk-of-autism-spectrum-disorder
#4
Ousseny Zerbo, Yinge Qian, Cathleen Yoshida, Bruce H Fireman, Nicola P Klein, Lisa A Croen
Importance: Maternal infections and fever during pregnancy are associated with increased risk for autism spectrum disorders (ASDs). To our knowledge, no study has investigated the association between influenza vaccination during pregnancy and ASD. Objective: To investigate the association between influenza infection and vaccination during pregnancy and ASD risk. Design, Setting, and Participants: This cohort study included 196 929 children born at Kaiser Permanente Northern California from January 1, 2000 to December 31, 2010, at a gestational age of at least 24 weeks...
November 28, 2016: JAMA Pediatrics
https://www.readbyqxmd.com/read/27890829/antenatal-exposure-to-antidepressants-is-associated-with-altered-brain-development-in-very-preterm-born-neonates
#5
Samantha K Podrebarac, Emma G Duerden, Vann Chau, Ruth E Grunau, Anne Synnes, Tim F Oberlander, Steven P Miller
BACKGROUND: Antenatal exposure to selective serotonin reuptake inhibitors (SSRI) is associated with an enhanced risk of preterm birth. Very preterm-born neonates (<32-week gestation) antenatally-exposed to SSRIs may show altered brain development. OBJECTIVE: To examine whether antenatal-SSRI exposure was associated with adverse neonatal brain microstructural and metabolic development using diffusion tensor and magnetic resonance spectroscopic imaging. DESIGN/METHODS: Of 177 neonates enrolled, 14 (8%) were antenatally exposed to SSRIs...
November 25, 2016: Neuroscience
https://www.readbyqxmd.com/read/27888119/prenatal-phthalate-triclosan-and-bisphenol-a-exposures-and-child-visual-spatial-abilities
#6
Joseph M Braun, David C Bellinger, Russ Hauser, Robert O Wright, Aimin Chen, Antonia M Calafat, Kimberly Yolton, Bruce P Lanphear
INTRODUCTION: During fetal development, sex steroids influence sexually dimorphic behaviors, such as visual-spatial abilities. Thus, endocrine disrupting chemicals that impact sex steroids during gestation may affect these behaviors. OBJECTIVE: We investigated the relationship between prenatal urinary phthalate metabolite, triclosan, and BPA concentrations and visual-spatial abilities in a prospective cohort of 198 mother-child dyads. METHODS: Data are from a prospective cohort in Cincinnati, OH (HOME Study)...
November 23, 2016: Neurotoxicology
https://www.readbyqxmd.com/read/27885356/magnetization-transfer-and-amide-proton-transfer-mri-of-neonatal-brain-development
#7
Yang Zheng, Xiaoming Wang, Xuna Zhao
Purpose. This study aims to evaluate the process of brain development in neonates using combined amide proton transfer (APT) imaging and conventional magnetization transfer (MT) imaging. Materials and Methods. Case data were reviewed for all patients hospitalized in our institution's neonatal ward. Patients underwent APT and MT imaging (a single protocol) immediately following the routine MR examination. Single-slice APT/MT axial imaging was performed at the level of the basal ganglia. APT and MT ratio (MTR) measurements were performed in multiple brain regions of interest (ROIs)...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27879450/human-placental-arterial-distensibility-birth-weight-and-body-size-are-positively-related-to-fetal-homocysteine-concentration
#8
Stephen W D'Souza, Nita Solanky, Jane Guarino, Stuart Moat, Colin P Sibley, Michael Taggart, Jocelyn D Glazier
Methionine demethylation during metabolism generates homocysteine (Hcy) and its remethylation requires folate and cobalamin. Elevated Hcy concentrations are associated with vascular-related complications of pregnancy, including increased vascular stiffness, predictive of clinical vascular disease. Maternal and fetal total Hcy (tHcy) concentrations are positively related, yet the influence of Hcy on fetoplacental vascular function in normal pregnancy has not been examined. We hypothesized that Hcy alters fetoplacental vascular characteristics with influences on fetal growth outcomes...
November 21, 2016: Reproductive Sciences
https://www.readbyqxmd.com/read/27878457/poorly-understood-and-often-miscategorized-congenital-umbilical-cord-hernia-an-alternative-repair-method
#9
E İnce, A Temiz, S S Ezer, H Ö Gezer, A Hiçsönmez
PURPOSE: Umbilical cord hernia is poorly understood and often miscategorized as "omphalocele minor". Careless clamping of the cord leads to iatrogenic gut injury in the situation of umbilical cord hernia. This study aimed to determine the characteristics and outcomes of umbilical cord hernias. We also highlight an alternative repair method for umbilical cord hernias. METHODS: We recorded 15 cases of umbilical cord hernias over 10 years. The patients' data were retrospectively reviewed, and preoperative preparation of the newborn, gestational age, birth weight, other associated malformations, surgical technique used, enteral nutrition, and length of hospitalization were recorded...
November 22, 2016: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/27871469/placental-telomere-length-decline-with-gestational-age-differs-by-sex-and-tert-dnmt1-and-dnmt3a-dna-methylation
#10
Samantha L Wilson, Yao Liu, Wendy P Robinson
INTRODUCTION: Telomere length (TL) has been suggested to be influenced by inherited genetic and epigenetic variation, hormonal effects, oxidative stress and age. However, the dynamics of TL during in utero development have not been well explored. This study investigates the relationship between placental TL and sex, gestational age (GA), and DNA methylation (DNAm). Placental TL is further evaluated in pregnancies complicated by preeclampsia (PE) and intrauterine growth restriction (IUGR), conditions hypothesized to lead to decreased placental TL due to increased oxidative stress...
December 2016: Placenta
https://www.readbyqxmd.com/read/27866039/sleep-eeg-maps-the-functional-neuroanatomy-of-executive-processes-in-adolescents-born-very-preterm
#11
Flavia M Wehrle, Beatrice Latal, Ruth L O'Gorman, Cornelia F Hagmann, Reto Huber
Executive function deficits are among the most frequent sequela of very preterm birth but the underlying neuronal mechanisms are not fully understood. We used high-density electroencephalography (EEG) recordings during sleep to assess alterations in the functional neuroanatomy of executive processes in adolescents born very preterm. The topographical distribution of sleep slow wave activity (SWA; 1-4.5 Hz EEG power) has previously been used to map cognitive abilities and is known to reflect the intensity of the prior use of the respective neuronal networks...
October 28, 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/27854382/the-truffle-study-fetal-monitoring-indications-for-delivery-in-310-iugr-infants-with-2-year-s-outcome-delivered-before-32-weeks-of-gestation
#12
Gerard H A Visser, C M Bilardo, J B Derks, E Ferrazzi, N Fratelli, T Frusca, W Ganzevoort, C Lees, R Napolitano, T Todros, H Wolf, K Hecher, N Marlow, B Arabin, C Brezinka, A Diemert, J J Duvekot, P Martinelli, E Ostermayer, A T Papageorghiou, D Schlembach, Ktm Schneider, B Thilaganathan, A Valcamonico
OBJECTIVE: In the TRUFFLE study on outcome of early fetal growth restriction women were allocated to three timing of delivery plans according to antenatal monitoring strategies based on reduced computerized cardiotocographic heart rate short term variation (c-CTG STV) , early Ductus Venosus (DV p95) or late DV (DV noA) changes. However, many infants were per protocol delivered because of 'safety net' criteria, or for maternal indications, or 'other fetal indications' or after 32 weeks of gestation when the protocol was not applied anymore...
November 11, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27851778/risk-factors-of-early-otitis-media-in-the-danish-national-birth-cohort
#13
Asbjørn Kørvel-Hanquist, Anders Koch, Janni Niclasen, Jesper Dammeye, Jørgen Lous, Sjurdur Frodi Olsen, Preben Homøe
OBJECTIVE: To assess risk factors of otitis media (OM) in six-months-old children. METHOD: The sample consisted of 69,105 mothers and their children from the Danish National Birth Cohort. The women were interviewed twice during pregnancy and again 6 months after birth. The outcome "one or more" maternal reported episodes of OM at age six months. In total 37 factors were assessed, covering prenatal, maternal, perinatal and postnatal factors. RESULTS: At age six months 5...
2016: PloS One
https://www.readbyqxmd.com/read/27848129/neonatal-risk-mortality-scores-as-predictors-for-health-related-quality-of-life-of-infants-treated-in-nicu-a-prospective-cross-sectional-study
#14
K Lah Tomulic, J Mestrovic, M Zuvic, K Rubelj, B Peter, I Bilic Cace, A Verbic
PURPOSE: To determine the relationship of Apgar scores, gestational age and neonatal risk mortality scores to health-related quality of life (HRQoL) for infants at the age of 8 months treated after birth in neonatal intensive care unit (NICU). METHODS: All surviving infants treated in two-third level NICUs in Rijeka, Croatia (from August 2013 to August 2014) were included in this prospective, cross-sectional study. For all neonates, the Score for Neonatal Acute Physiology (SNAP), SNAP with Perinatal Extension (SNAP-PE) and their simplified modifications (SNAP II and SNAP-PE II) were calculated...
November 15, 2016: Quality of Life Research
https://www.readbyqxmd.com/read/27829004/outcome-at-two-years-of-very-preterm-infants-born-after-rupture-of-membranes-before-viability
#15
Amelie Kieffer, Gaelle Pinto Cardoso, Caroline Thill, Eric Verspyck, Stéphane Marret
PURPOSE: To compare the respiratory and neurological outcomes at two years of age of preterm children born before 33 weeks of gestation (WG) after early preterm premature rupture of membranes (EPPROM) between 14 and 24 WG with preterm children without EPPROM. DESIGN AND PATIENTS: This single-center case-control retrospective study was conducted at Rouen University Hospital between 1st January 2000 and 31st December 2010. All the cases with EPPROM born from 26WG to 32WG were included...
2016: PloS One
https://www.readbyqxmd.com/read/27825008/effect-of-supplemental-donor-human-milk-compared-with-preterm-formula-on-neurodevelopment-of-very-low-birth-weight-infants-at-18-months-a-randomized-clinical-trial
#16
COMMENT
Deborah L O'Connor, Sharyn Gibbins, Alex Kiss, Nicole Bando, Joan Brennan-Donnan, Eugene Ng, Douglas M Campbell, Simone Vaz, Christoph Fusch, Elizabeth Asztalos, Paige Church, Edmond Kelly, Linh Ly, Alan Daneman, Sharon Unger
Importance: For many very low-birth-weight (VLBW) infants, there is insufficient mother's milk, and a supplement of pasteurized donor human milk or preterm formula is required. Awareness of the benefits of mother's milk has led to an increase in use of donor milk, despite limited data evaluating its efficacy. Objective: To determine if nutrient-enriched donor milk compared with formula, as a supplement to mother's milk, reduces neonatal morbidity, supports growth, and improves neurodevelopment in VLBW infants...
November 8, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27819553/pt-vwd-posing-diagnostic-and-therapeutic-challenges-small-case-series
#17
Analía Sánchez-Luceros, Adriana I Woods, Emilse Bermejo, Shilpa Shukla, Suchitra Acharya, Michelle Lavin, Natalia Rydz, Maha Othman
Despite the increased worldwide awareness, over the last decade, of the platelet-type von Willebrand Disease (PT-VWD), many uncertainties remain around this rare platelet bleeding disorder. This report aims to correctly identify and study the phenotype of new patients and highlights the diagnostic and therapeutic challenges this disease remains to pose. We describe four PT-VWD cases confirmed by genetic analysis in which either the diagnosis and/or the treatment posed challenge. We provide the details of the clinical presentation, laboratory analysis, and the treatment and the responses in each case...
November 7, 2016: Platelets
https://www.readbyqxmd.com/read/27819175/early-versus-late-inguinal-hernia-repair-in-extremely-low-birth-weight-infants
#18
Rajesh Pandey, Joleen Dako, Sarah Venus, Deepak Kumar, Maroun Mhanna
OBJECTIVE: Compare outcomes of Extremely Low Birth Weight (ELBW) Infants following early (before discharge) versus late (after discharge) inguinal hernia (IH) repair. STUDY DESIGN: In a retrospective study of ELBW infants with IH, data was abstracted for clinical characteristics, IH and related outcomes. RESULT: Of the 39/252 (15.4%) ELBW infants who developed IH, those with early (59%) versus late (41%) repair were comparable in birth weight (753±158 vs...
November 6, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27818077/altered-growth-trajectory-of-head-circumference-during-infancy-and-schizophrenia-in-a-national-birth-cohort
#19
Alan S Brown, David Gyllenberg, Susanna Hinkka-Yli-Salomäki, Andre Sourander, Ian W McKeague
Identification of abnormalities in the developmental trajectory during infancy of future schizophrenia cases offers the potential to reveal pathogenic mechanisms of this disorder. Previous studies of head circumference in pre-schizophrenia were limited to measures at birth. The use of growth acceleration of head circumference (defined as the rate of change in head circumference) provides a more informative representation of the maturational landscape of this measure compared to studies based on static head circumference measures...
November 4, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/27816220/using-eye-movements-to-assess-language-comprehension-in-toddlers-born-preterm-and-full-term
#20
Elizabeth C Loi, Virginia A Marchman, Anne Fernald, Heidi M Feldman
OBJECTIVE: To assess language skills in children born preterm and full term by the use of a standardized language test and eye-tracking methods. STUDY DESIGN: Children born ≤32 weeks' gestation (n = 44) were matched on sex and socioeconomic status to children born full term (n = 44) and studied longitudinally. The Bayley Scales of Infant and Toddler Development, Third Edition (BSID-III) were administered at 18 months (corrected for prematurity as applicable)...
November 3, 2016: Journal of Pediatrics
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