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https://www.readbyqxmd.com/read/29775774/hospital-admissions-2000-2014-a-retrospective-analysis-of-288-096-events-in-patients-with-dementia
#1
Catarina Bernardes, João Massano, Alberto Freitas
INTRODUCTION: Dementia is a leading cause of disability worldwide. It is associated with an increased risk of hospitalization, imposing a significant burden on healthcare systems. The evidence on the long-term evolution of this issue and broadly on healthcare systems is currently limited. This study aims to describe the hospitalizations of people who received a diagnosis of dementia admitted to public general hospitals in a western European country with universal health coverage, over more than a decade...
May 8, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29771779/cost-of-integrating-non-communicable-disease-screening-into-home-based-hiv-testing-and-counseling-in-south-africa
#2
Ilya Golovaty, Monisha Sharma, Alastair Van Heerden, Heidi van Rooyen, Jared M Baeten, Connie Celum, Ruanne V Barnabas
INTRODUCTION: Integrated HIV-non-communicable disease (NCD) services have the potential to avert death and disability, but require data on program costs to assess the impact of integrated services on affordability. METHODS: We estimated the incremental costs of NCD screening as part of home-based HIV testing and counseling (HTC) and referral to care in KwaZulu-Natal, South Africa. All adults in the households were offered integrated HIV-NCD screening (for HIV, diabetes, hypertension, hypercholesterolemia, obesity, depression, tobacco and alcohol use), counseling, and linkage to care...
May 10, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29768584/mortality-from-type-2-diabetes-and-implementation-of-the-prevenimss-program-a-time-series-study-in-mexico-1998-2015
#3
Oswaldo Sinoe Medina-Gómez, Ismael Seth Medina-Reyes
Type 2 diabetes is the leading cause of morbidity and mortality in the world. In Mexico it is the first cause of mortality, disability, and potential years of life lost due to premature death. The Mexican Institute of Social Security (IMSS) implemented the PREVENIMSS strategy. The aim of the current study was to estimate the program's effect on the mortality trend from type 2 diabetes, based on an interrupted time series analysis. At the beginning of the target period, the diabetes mortality rate was higher in IMSS beneficiaries than in the control population...
May 10, 2018: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/29764278/eating-well-living-well-and-weight-management-a-co-produced-semi-qualitative-study-of-barriers-and-facilitators-experienced-by-adults-with-intellectual-disabilities
#4
A J Doherty, S P Jones, U Chauhan, Jme Gibson
Adults with intellectual disabilities in England experience health inequalities. They are more likely than their non-disabled peers to be obese and at risk of serious medical conditions such as heart disease, stroke and type 2 diabetes. This semi-qualitative study engaged adults with intellectual disabilities in a co-production process to explore their perceived barriers and facilitators to eating well, living well and weight management. Nineteen participants with intellectual disabilities took part in four focus groups and one wider group discussion...
January 1, 2018: Journal of Intellectual Disabilities: JOID
https://www.readbyqxmd.com/read/29764275/the-experience-of-type-2-diabetes-self-management-in-adults-with-intellectual-disabilities-and-their-caregivers-a-review-of-the-literature-using-meta-aggregative-synthesis-and-an-appraisal-of-rigor
#5
Andrew Maine, Michael Brown, Adele Dickson, Maria Truesdale
People with intellectual disabilities (ID) experience significant barriers to diabetes self-management (DSM), yet there remains a paucity of research within this population. An overview of the literature on people with ID and their caregivers' experiences of living with and self-managing type 2 diabetes is provided. Meta-aggregative methods were adopted to synthesize results, and an appraisal was reported of rigor. A total of eight studies met the inclusion criteria and four themes were extracted: (i) "Frustration over lifestyle adjustments," (ii) "Limited understanding and inadequate educational resources," (iii) "Limited training and knowledge in staff," and (iv) "Potential for effective DSM with appropriate support...
January 1, 2018: Journal of Intellectual Disabilities: JOID
https://www.readbyqxmd.com/read/29751618/a-cost-benefit-analysis-of-an-active-travel-intervention-with-health-and-carbon-emission-reduction-benefits
#6
Ralph Chapman, Michael Keall, Philippa Howden-Chapman, Mark Grams, Karen Witten, Edward Randal, Alistair Woodward
Active travel (walking and cycling) is beneficial for people’s health and has many co-benefits, such as reducing motor vehicle congestion and pollution in urban areas. There have been few robust evaluations of active travel, and very few studies have valued health and emissions outcomes. The ACTIVE before-and-after quasi-experimental study estimated the net benefits of health and other outcomes from New Zealand’s Model Communities Programme using an empirical analysis comparing two intervention cities with two control cities...
May 11, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29749025/photobiomodulation-induces-antinociception-recovers-structural-aspects-and-regulates-mitochondrial-homeostasis-in-peripheral-nerve-of-diabetic-mice
#7
Victória Regina da Silva de Oliveira, Diego Pulzatto Cury, Laura Basílio Yamashita, Marcos Vinicius Esteca, Ii-Sei Watanabe, Yoko Fee Bergmann, Elaine Flamia Toniolo, Camila Squarzoni Dale
Diabetic Peripheral Neuropathy (DPN) is a nervous disorder caused by diabetes mellitus, affecting about 50% of patients in clinical medicine. Chronic pain is one of the major and most unpleasant symptoms developed by those patients, and conventional available treatments for the neuropathy, including the associated pain, are still unsatisfactory and benefit only a small number of patients. Photobiomodulation (PBM) has been gaining clinical acceptance once it is able to promote early nerve regeneration resulting in significant improvement peripheral nerves disabilities...
May 11, 2018: Journal of Biophotonics
https://www.readbyqxmd.com/read/29748945/causes-of-low-vision-and-blindness-in-a-turkish-adult-population-the-izmir-eye-study
#8
Feray Koç, Veysi Erden, Nazife Sefi-Yurdakul
Background: Data from Turkey show that sense organ diseases were the second leading cause of years lost due to disability in 2015. However, there are no reliable data on either the baseline causative disorders of visual impairment or the burden of these disorders on the population in Izmir region. Izmir is the third most populated city of Turkey with a population of approximately 4.2 million. Aim: The purpose of this study was to define the baseline disorders causing low vision and blindness in accordance with World Health Organization criteria in an adult population in Izmir...
May 3, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29742480/clinical-benefits-and-pharmacology-of-scutellarin-a-comprehensive-review
#9
REVIEW
Liping Wang, Qiang Ma
Stroke and myocardial infarction are among the most common causes of mortality and disability in the world. The ischemic injury underlying these illnesses is complex, involving intricate interplays among many biological functions including energy metabolism, vascular regulation, hemodynamics, oxidative stress, inflammation, platelet activation, and tissue repair that take place in a context- and time-dependent manner. The current drug therapy of choice is to timely resupply the blood to the ischemic tissue; but reperfusion may introduce additional harm to the tissue through a process known as ischemia/reperfusion injury...
May 6, 2018: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29737001/clinical-and-functional-characterization-of-two-novel-zbtb20-mutations-causing-primrose-syndrome
#10
Emilia Stellacci, Katharina Steindl, Pascal Joset, Laura Mercurio, Massimiliano Anselmi, Serena Cecchetti, Laura Gogoll, Markus Zweier, Annette Hackenberg, Gianfranco Bocchinfuso, Lorenzo Stella, Marco Tartaglia, Anita Rauch
Primrose syndrome (PS) is a rare disorder characterized by macrocephaly, tall stature, intellectual disability, autistic traits, and disturbances of glucose metabolism with insulin-resistant diabetes and distal muscle wasting occurring in adulthood. The disorder is caused by functional dysregulation of ZBTB20, a transcriptional repressor controlling energetic metabolism and developmental programs. ZBTB20 maps in a genomic region that is deleted in the 3q13.31 microdeletion syndrome, which explains the clinical overlap between the two disorders...
May 7, 2018: Human Mutation
https://www.readbyqxmd.com/read/29731294/derivation-and-validation-of-a-predictive-model-for-the-readmission-of-patients-with-diabetes-mellitus-treated-in-internal-medicine-departments
#11
J Ena, R Gómez-Huelgas, B C Gracia-Tello, P Vázquez-Rodríguez, J N Alcalá-Pedrajas, F J Carrasco-Sánchez, B Murcia-Casas, M Romero-Sánchez, J V Segura-Heras, J Carretero
OBJECTIVES: We developed a predictive model for the hospital readmission of patients with diabetes. The objective was to identify the frail population that requires additional strategies to prevent readmissions at 90 days. METHODS: Using data collected from 1977 patients in 3 studies on the national prevalence of diabetes (2015-2017), we developed and validated a predictive model of readmission at 90 days for patients with diabetes. RESULTS: A total of 704 (36%) readmissions were recorded...
May 4, 2018: Revista Clínica Española
https://www.readbyqxmd.com/read/29728312/disability-and-not-diabetes-is-a-strong-predictor-of-mortality-in-oldest-old-patients-hospitalized-with-pneumonia
#12
S Corrao, C Argano, G Natoli, A Nobili, G R Corazza, P M Mannucci, F Perticone
BACKGROUND: Pneumonia causes more deaths than any other infectious disease, especially in older patients with multiple chronic diseases. Recent studies identified a low functional status as prognostic factor for mortality in elderly patients with pneumonia while contrasting data are available about the role of diabetes. The aim of this study was to evaluate the in-hospital, 3-month and 1-year mortality in elderly subjects affected by pneumonia enrolled in the RePoSi register. METHODS: We retrospectively analyzed the data collected on hospitalized elderly patients in the frame of the REPOSI project...
May 1, 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29725171/does-metabolic-syndrome-determine-severity-and-disability-of-chronic-low-backache
#13
Jayantee Kalita, Kamlesh Kumar Sonkar, Usha Kant Misra, Sanjeev K Bhoi
Introduction: Obesity may be associated with more severe and disabling low backache (LBA) due to alteration in biomechanics, but there are no such studies from developing countries. Aims: We report the frequency of metabolic syndrome (MS) in chronic LBA (CLBA) and its association with severity and disability of CLBA. Subjects and Methods: Consecutive patients with CLBA attending to the neurology service from October 2015 to February 2016 were included in the study...
April 2018: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29724093/the-effect-of-postoperative-use-of-teriparatide-reducing-screw-loosening-in-osteoporotic-patients
#14
Jae Wook Kim, Seung Won Park, Young Baeg Kim, Myeong Jin Ko
Objective: The loosening of pedicle screws (PS) is one of the frequent problems of spinal surgery in the patients with osteoporosis. Previous studies had revealed that intermittent injection of teriparatide could reduce PS loosening by improving bone mass and quality when their patients took parathyroid hormone for a considerable duration before surgery. However, although the teriparatide is usually used after spine surgery in most clinical situations, there was no report on the efficacy of teriparatide treatment started after spine surgery...
May 4, 2018: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29721235/does-alpha-lipoic-acid-supplementation-modulate-cardiovascular-risk-factors-in-patients-with-stroke-a-randomized-double-blind-clinical-trial
#15
Vida Mohammadi, Fariborz Khorvash, Awat Feizi, Gholamreza Askari
Background: Stroke as a devastating condition is one of the major causes of death worldwide. It is accountable for long time disability with high personal and social cost in adults. There are several risk factors for stroke such as diabetes and hypertension. Alpha-lipoic acid (ALA) as an antioxidant can be a risk modifier in these patients. We designed this trial to scrutinize the possible effects of ALA consumption on some cardiovascular risk factors in patients experienced stroke. Methods: In this randomized, double-blind, placebo-controlled clinical trial, 67 patients experienced stroke were randomly allocated into two groups (taking a 600 mg ALA supplement or placebo daily for 12 weeks)...
2018: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29720799/phrenic-nerve-conduction-study-in-the-early-stage-of-guillain-barre-syndrome-as-a-predictor-of-respiratory-failure
#16
Barun Kumar Sen, Alak Pandit
Background: Guillain-Barré syndrome (GBS) has unpredictable clinical course with severe complication of respiratory failure. Objective: To identify clinical profiles and electrophysiological study particularly non-invasive Phrenic nerve conduction study in patients of early GBS to predict respiratory failure. Methods: 64 adult (age≥18yrs) patients of early GBS (onset ≤ 14 days) during the study period from January 2014 to October 2015 were evaluated by clinical profiles of age, gender, antecedent infection, time to peak disability, single breath counts, cranial nerve involvement, autonomic dysfunction and non-invasive Phrenic nerve conduction study...
January 2018: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/29713494/developing-and-feasibility-testing-of-data-collection-methods-for-an-economic-evaluation-of-a-supported-selfmanagement-programme-for-adults-with-a-learning-disability-and-type-2-diabetes
#17
John L O'Dwyer, Amy M Russell, Louise D Bryant, Rebecca E A Walwyn, Alexandra M Wright-Hughes, Elizabeth H Graham, Judy M Wright, Shaista Meer, Jacqueline Birtwistle, Amanda J Farrin, Allan O House, Claire T Hulme
Background: The challenges of conducting research with hard to reach vulnerable groups are particularly pertinent for people with learning disabilities. Data collection methods for previous cost and cost-effectiveness analyses of health and social care interventions targeting people with learning disabilities have relied on health care/health insurance records or data collection forms completed by the service provider rather than by people with learning disabilities themselves. This paper reports on the development and testing of data collection methods for an economic evaluation within a randomised controlled trial (RCT) for a supported self-management programme for people with mild/moderate learning disabilities and type 2 diabetes...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29710725/prevalence-of-dementia-and-associated-risk-factors-a-population-based-study-in-the-philippines
#18
Jacqueline Dominguez, Ma Fe de Guzman, Macario Reandelar, Thien Kieu Thi Phung
BACKGROUND: The Philippines is experiencing rapid demographic aging and with it, the dementia epidemic. Prevalence of dementia and associated risk factors have not been studied in the Philippines. OBJECTIVES: The study aimed to provide a reliable estimate of dementia prevalence and identify associated risk factors in the Filipino population. METHODS: 1460 participants 60 years and older were randomly selected from the Marikina City's senior registry...
April 25, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29706999/the-association-between-serum-bilirubin-level-and-electrochemical-skin-conductance-in-chinese-patients-with-type-2-diabetes
#19
Fei Mao, Xiaoming Zhu, Bin Lu, Yiming Li
Bilirubin is an antioxidant and plays a protective role against cardiovascular and microvascular disease. The aim of this study is to explore the possible protective effect of bilirubin on small nerve function. A total of 265 Chinese patients with type 2 diabetes mellitus (T2DM) were enrolled in the study. Both SUDOSCAN and other traditional diabetic neuropathy examinations including neuropathy symptom score (NSS), the neuropathy disability score (NDS) and Michigan Neuropathy Screening Instrument (MNSI) scores were performed in all patients with T2DM...
2018: International Journal of Endocrinology
https://www.readbyqxmd.com/read/29706931/interaction-of-sex-and-diabetes-on-outcome-after-ischemic-stroke
#20
Maria Montserrat Soriano-Reixach, Rosa María Vivanco-Hidalgo, Angel Ois, Ana Rodríguez-Campello, Jaume Roquer
Background: The relationship between ischemic stroke (IS), diabetes mellitus (DM), and sex is intriguing. The aim of this study was to assess the effect modification of sex in the association between DM and short- and long-term disability and mortality in first-ever IS patients. Methods: In a retrospective, observational, hospital-based study of a prospective series including first-ever IS patients from January 2006 until July 2011, differences in 3-month and 5-year mortality, and disability between diabetic and non-diabetic patients [modified Rankin Scale (mRS) from 3 to 5] were analyzed by sex...
2018: Frontiers in Neurology
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