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https://www.readbyqxmd.com/read/29340965/emotional-and-social-characteristics-of-stroke-patients-with-low-verbal-memory
#1
Ewa Zawadzka, Łucja Domańska
BACKGROUND: Cognitive deficits, especially problems with memory observed after stroke often coexist with patients' experience of difficulties in everyday life situations. AIMS: The purposes of the study were to explore the relationships between verbal memory, emotional functioning and social competence in stroke patients, and to examine the emotional and social condition of stroke patients with low verbal memory. METHODS: Ninety-five participants were assessed with the Rey Auditory Verbal Learning Test, the Neuropsychology Behavior and Affect Profile, and the Social Competency Questionnaire...
January 17, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29340270/outpatient-combined-use-of-opioid-and-benzodiazepine-medications-in-the-united-states-1993-2014
#2
Matthew E Hirschtritt, Kevin L Delucchi, Mark Olfson
The combined use of opioid and benzodiazepine medications increases the risk of hazardous effects, such as respiratory depression. Although recent increases in outpatient use of opioid prescriptions have been documented, there are limited data regarding rates and correlates of combined opioid and benzodiazepines among adults in outpatient settings. Our objective was to examine annual trends in outpatient visits including opioids, benzodiazepines, and their combination among adults as well as clinical and demographic correlates...
March 2018: Preventive Medicine Reports
https://www.readbyqxmd.com/read/29337023/the-effects-of-functional-training-bicycle-exercise-and-exergaming-on-walking-capacity-of-elderly-with-parkinson-s-disease-a-pilot-randomized-controlled-single-blinded-trial
#3
Daniel Dominguez Ferraz, Karen Valadares Trippo, Gabriel Pereira Duarte, Mansueto Gomes Neto, Kionna Oliveira Bernardes Santos, Jamary Oliveira Filho
OBJECTIVES: To compare the effects of functional training, bicycle exercise and exergaming on walking capacity of elderly with Parkinson disease (PD). DESIGN: A pilot randomized controlled single-blinded trial. SETTING: A State Reference Health Care Centre for Elderly, a public reference outpatient clinic for the elderly. PARTICIPANTS: Sixty-two elderly individuals (≥60 years-old) with idiopathic PD (stage 2 to 3 of modified Hoehn and Yahr) according to the London Brain Bank...
January 11, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29334234/is-there-an-association-between-severity-of-illness-and-psychiatric-symptoms-in-patients-with-chronic-renal-failure
#4
D Guenzani, M Buoli, G S Carnevali, M Serati, P Messa, S Vettoretti
Chronic renal failure (CRF) is a frequent condition in elderly subjects, and it is associated with psychiatric comorbidity, especially depressive symptoms. Purpose of the present research was to compare patients with different severity of chronic kidney disease (CKD) in terms of psychiatric symptoms. One hundred CKD subjects were randomly selected among those attending the Department of Nephrology, University of Milan. The patients were evaluated through the following rating scales: Mini-Mental State Examination (MMSE), Beck Depression Inventory (BDI), Symptom Checklist (SCL-90), Kidney Disease Quality of Life- Short Form (KDQOL-SF) and Cumulative Illness Rating Scale (CIRS)...
January 15, 2018: Psychology, Health & Medicine
https://www.readbyqxmd.com/read/29334228/use-of-ect-in-the-presence-of-acute-bilateral-posterior-vitreous-detachmanet
#5
Tesema Taye, Letitia Dobranici, Mark Fisher, Sarah Cullum
OBJECTIVES: We describe a case of acute bilateral posterior vitreous detachment (PVD) in a 71-year-old female, which developed during a course of electroconvulsive therapy (ECT) for treatment-resistant depression. The risks and benefits of continuing ECT were assessed and the patient completed the full course of 16 ECT treatments without further ophthalmic complications. CONCLUSIONS: As the incidence of PVD increases with age, and ECT is used more frequently in elderly people with depression, we recommend paying attention to ophthalmic symptoms as part of the routine clinical monitoring of ECT side effects...
January 1, 2018: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/29332036/relationships-between-lower-olfaction-and-brain-white-matter-lesions-in-elderly-subjects-with-mild-cognitive-impairment
#6
Juliette Heinrich, Jean-Sébastien Vidal, Axelle Simon, Anne-Sophie Rigaud, Olivier Hanon, Jacques Epelbaum, Cecile Viollet, Emmanuelle Duron
BACKGROUND: Olfactory impairment is reported in mild cognitive impairment (MCI) and Alzheimer's disease (AD) and is associated with hippocampal atrophy. In elderly people, dementia with AD neuropathology and white matter lesions (WML) is common. In this context, olfactory impairment could also depend on the presence of WML. OBJECTIVE: To assess the cross-sectional relationship between olfaction and WML in elderly subjects with MCI. METHODS: Consecutive subjects, >65 years old, diagnosed as MCI after a comprehensive neuropsychological assessment in an expert memory center, with a brain MRI performed within a year and without major depressive state, were included...
2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29331872/effect-of-physical-activity-on-cognitive-flexibility-depression-and-rbd-in-healthy-elderly
#7
Stefanie Lerche, Alexandra Gutfreund, Kathrin Brockmann, Markus A Hobert, Isabel Wurster, Ulrike Sünkel, Gerhard W Eschweiler, Florian G Metzger, Walter Maetzler, Daniela Berg
OBJECTIVE: The prevalence of Alzheimer's disease and Parkinson's disease increases with the raising number of elderly, which will be a challenging situation for the healthcare systems and society in the future. There is evidence that there are modifiable risk-factors e.g. physical activity for these diseases. Here, we study the interaction between sports inactivity with prodromal markers for neurodegeneration. PATIENTS AND METHODS: We investigated 667 neurologically healthy individuals cross-sectional and a subgroup longitudinal over six years...
January 9, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29325447/longitudinal-association-of-amyloid-beta-and-anxious-depressive-symptoms-in-cognitively-normal-older-adults
#8
Nancy J Donovan, Joseph J Locascio, Gad A Marshall, Jennifer Gatchel, Bernard J Hanseeuw, Dorene M Rentz, Keith A Johnson, Reisa A Sperling
OBJECTIVE: To understand the role of depressive symptoms in preclinical Alzheimer's disease, it is essential to define their temporal relationship to Alzheimer's proteinopathies in cognitively normal older adults. The study objective was to examine associations of brain amyloid beta and longitudinal measures of depression and depressive symptom clusters in a cognitively normal sample of older adults. METHOD: A total of 270 community-dwelling, cognitively normal elderly individuals underwent baseline Pittsburgh compound B (PiB) positron emission tomography (PET) measures of cortical aggregate amyloid beta and annual assessments with the 30-item Geriatric Depression Scale (GDS)...
January 12, 2018: American Journal of Psychiatry
https://www.readbyqxmd.com/read/29324370/model-based-comparing-efficacy-of-fluoxetine-between-elderly-and-non-elderly-participants-with-major-depressive-disorder
#9
Lidan Dong, Ling Xu, Yanfei Li, Yinghua Lv, Hongxia Liu, Yunfei Li, Fengyan Xu, Junyi Wu, Qingshan Zheng, Lujin Li
BACKGROUND: The high heterogeneity was existed among the studies of the elderly participants with major depressive disorder (MDD), which may lead to incorrect conclusions in the previous meta-analysis. This study used model based meta-analysis to compare the efficacy of fluoxetine between the elderly and non-elderly participants with MDD and to explain the heterogeneity among the studies. METHODS: A comprehensive literature search was conducted in the public databases, involving utilization of fluoxetine for treating MDD in the acute-phase...
January 3, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29321592/amyloid-%C3%AE-causes-excitation-inhibition-imbalance-through-dopamine-receptor-1-dependent-disruption-of-fast-spiking-gabaergic-input-in-anterior-cingulate-cortex
#10
Si-Qiang Ren, Wen Yao, Jing-Zhi Yan, Chunhui Jin, Jia-Jun Yin, Jianmin Yuan, Shui Yu, Zaohuo Cheng
Alzheimer's disease (AD) is the most common cause of dementia in the elderly. At the early stages of AD development, the soluble β-amyloid (Aβ) induces synaptic dysfunction, perturbs the excitation/inhibition balance of neural circuitries, and in turn alters the normal neural network activity leading to cognitive decline, but the underlying mechanisms are not well established. Here by using whole-cell recordings in acute mouse brain slices, we found that 50 nM Aβ induces hyperexcitability of excitatory pyramidal cells in the cingulate cortex, one of the most vulnerable areas in AD, via depressing inhibitory synaptic transmission...
January 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29316345/factors-related-to-frailty-among-the-elderly-in-south-korea-a-3-year-longitudinal-study
#11
Jin-Kyoung Park, Jong-Eun Lee
PURPOSE: To examine factors associated with frailty among the young-old elderly (YOE) and old-old elderly (OOE). METHODS: This longitudinal study with a 3-year follow-up included 486 participants who received home care services. FINDINGS: Precipitous weight loss and depression in the YOE and worsening of complex mobility and depression in the OOE were associated with worsened frailty over the 3-year period. CONCLUSIONS: To prevent frailty, we suggest weight-loss prevention programs for the YOE, lower-limb exercise programs for the OOE, and depression management programs for both groups...
January 5, 2018: International Journal of Nursing Knowledge
https://www.readbyqxmd.com/read/29313171/gender-effect-on-well-being-of-the-oldest-old-a-survey-of-nonagenarians-living-in-tuscany-the-mugello-study
#12
Luca Padua, Patrizio Pasqualetti, Daniele Coraci, Isabella Imbimbo, Alessandro Giordani, Claudia Loreti, Camillo Marra, Raffaello Molino-Lova, Guido Pasquini, Ilaria Simonelli, Federica Vannetti, Claudio Macchi
The population of industrialized nations is progressively aging, with Italy having one of the most elderly populations in the world. Natural aging may be associated with physical and cognitive impairments, often straining public resources. The present study aims to investigate the influence of gender on wellness of the nonagenarians. We evaluated quality of life among nonagenarians living in the Mugello area, an Italian location with a large population of individuals > 90 years, using the Health Survey Scoring SF-12...
January 8, 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29310620/does-presence-of-metabolic-syndrome-impact-anxiety-and-depressive-disorder-screening-results-in-middle-aged-and-elderly-individuals-a-population-based-study
#13
Jurate Butnoriene, Vesta Steibliene, Ausra Saudargiene, Adomas Bunevicius
BACKGROUND: Depressive and anxiety disorders are common in primary care setting but often remain undiagnosed. Metabolic syndrome (MetS) is also prevalent in the general population and can impair recognition of common mental disorders due to significant co-morbidity and overlap with psychiatric symptoms included in self-reported depression/anxiety screening tools. We investigated if MetS has an impact on the accuracy of current major depressive disorder (MDD) and generalized anxiety disorder (GAD) screening results using the Hospital Anxiety and Depression scale (HADS)...
January 8, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29306907/new-aspects-in-the-pathomechanism-of-diseases-of-civilization-particularly-psychosomatic-disorders-part-2-chronic-hypocapnia-and-hypercapnia-in-the-medical-practice
#14
Andras Sikter, Zoltan Rihmer, Roberto de Guevara
The authors seek to find new connections between recent results of biology and older theories. This paper aims to assemble the jigsaw puzzle. The theoretical background of the hypothesis was described in the previous issue of the journal (Sikter et al. 2017a). Human stress response often coexists with persistent hypocapnia or hypercapnia - developing via psychosomatic pathomechanism - which can lead to mental and psychosomatic illnesses. Chronic hypocapnia mainly generates hyperarousal disorders which may be reversible for an extended time, however, vicious cycles may start when hypoxia and/or severe somatic diseases are simultaneously present (commonly in the elderly), which conditions often end with death without medical help...
September 2017: Neuropsychopharmacologia Hungarica
https://www.readbyqxmd.com/read/29304204/death-depression-disability-and-dementia-associated-with-self-reported-hearing-problems-a-25-year-study
#15
Hélène Amieva, Camille Ouvrard, Céline Meillon, Laetitia Rullier, Jean-François Dartigues
Background: Hearing loss in older adults is suspected to play a role in social isolation, depression, disability, lower quality of life and risk of dementia. Such suspected associations still need to be consolidated with additional research. With a particularly long follow-up, this study assessed the relationship between hearing status and four major adverse health events: death, dementia, depression, and disability. Methods: Prospective community-based study of 3777 subjects aged ≥ 65 followed-up for 25 years...
January 3, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29302568/severe-hyponatremia-associated-with-escitalopram
#16
Gautam Rawal, Raj Kumar, Sankalp Yadav
Hyponatremia is a rare but potentially fatal complication of selective serotonin reuptake inhibitor (SSRI) therapy with only limited cases of escitalopram as the causative drug. We report the case of a 54-year-old hypertensive female who was admitted to the hospital with seizure episode and subsequently diagnosed to have severe hyponatremia due to SSRI-induced syndrome of inappropriate antidiuretic hormone (SIADH) with the cause attributed to the short history of intake of escitalopram for depression. All SSRIs, including escitalopram, can cause SIADH and should be used with caution in the depressive patients with regular monitoring of electrolytes, especially in the elderly...
April 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29302544/morbidity-pattern-and-its-sociodemographic-determinants-among-elderly-population-of-raichur-district-karnataka-india
#17
Leyanna Susan George, Sanjay Deshpande, M K Krishna Kumar, Ramesh S Patil
Context: India is an "aging nation" with 7.7% of its population being above 60 years of age. It has resulted in a rise of both physical and mental health morbidities. Aims: This study aimed to gather information regarding the morbidity pattern and its sociodemographic determinants among the elderly residing in the rural villages of Raichur, to understand the need for geriatric health-care facilities. Settings and Design: This community-based cross-sectional study was carried out in six rural villages of Raichur District, of which 230 elderly were selected randomly...
April 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29300436/serum-concentrations-of-25-hydroxyvitamin-d-and-depression-in-a-general-middle-aged-to-elderly-population-in-finland
#18
M Vidgren, J K Virtanen, T Tolmunen, T Nurmi, T-P Tuomainen, S Voutilainen, A Ruusunen
OBJECTIVES: Low concentrations of serum 25-hydroxyvitamin D [25(OH)D] have been postulated to associate with an increased prevalence of depression. As there are a limited number of publications on this issue, we examined the association between serum 25(OH)D and depression in a general middle-aged or older population. DESIGN: A population-based cross-sectional study. SETTING AND PARTICIPANTS: A total of 1602 men and women from the population-based Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD) in Eastern Finland, aged 53-73 y in 1998-2001, were analysed...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29300426/physical-frailty-is-associated-with-longitudinal-decline-in-global-cognitive-function-in-non-demented-older-adults-a-prospective-study
#19
S Chen, T Honda, K Narazaki, T Chen, H Kishimoto, Y Haeuchi, S Kumagai
OBJECTIVES: To assess the relationship between physical frailty and subsequent decline in global cognitive function in the non-demented elderly. DESIGN AND SETTING: A prospective population-based study in a west Japanese suburban town, with two-year follow-up. PARTICIPANTS: Community-dwellers aged 65 and older without placement in long-term care, and not having a history of dementia, Parkinson's disease and depression at baseline, who participated in the cohort of the Sasaguri Genkimon Study and underwent follow-up assessments two years later (N = 1,045)...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29300421/validity-of-the-self-mini-nutritional-assessment-self-mna-for-the-evaluation-of-nutritional-risk-a-cross-sectional-study-conducted-in-general-practice
#20
L M Donini, W Marrocco, C Marocco, A Lenzi
INTRODUCTION: Malnutrition is a frequent condition in the elderly especially in hospitals and in nursing homes, and even among the free-living elders the prevalence is not negligible (5-10%). Awareness towards malnutrition is still limited. The lack of time for nutritional assessment by the overcommitted healthcare personnel, including the general practitioners (GPs), may represent one possible explanation for limited recognition of malnutrition. Therefore, a self-administered instrument could be useful in raising alert on the GPs and allow early detection of malnutrition and early care provision...
2018: Journal of Nutrition, Health & Aging
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