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https://www.readbyqxmd.com/read/28542194/using-g6pd-tests-to-enable-the-safe-treatment-of-plasmodium-vivax-infections-with-primaquine-on-the-thailand-myanmar-border-a-cost-effectiveness-analysis
#1
Angela Devine, Minnie Parmiter, Cindy S Chu, Germana Bancone, François Nosten, Ric N Price, Yoel Lubell, Shunmay Yeung
BACKGROUND: Primaquine is the only licensed antimalarial for the radical cure of Plasmodium vivax infections. Many countries, however, do not administer primaquine due to fear of hemolysis in those with glucose-6-phosphate dehydrogenase (G6PD) deficiency. In other settings, primaquine is given without G6PD testing, putting patients at risk of hemolysis. New rapid diagnostic tests (RDTs) offer the opportunity to screen for G6PD deficiency prior to treatment with primaquine. Here we assessed the cost-effectiveness of using G6PD RDTs on the Thailand-Myanmar border and provide the model as an online tool for use in other settings...
May 24, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28540768/daily-stressors-trauma-exposure-and-mental-health-among-stateless-rohingya-refugees-in-bangladesh
#2
Andrew Riley, Andrea Varner, Peter Ventevogel, M M Taimur Hasan, Courtney Welton-Mitchell
The Rohingya of Myanmar are a severely persecuted minority who form one of the largest groups of stateless people; thousands of them reside in refugee camps in southeastern Bangladesh. There has been little research into the mental health consequences of persecution, war, and other historical trauma endured by the Rohingya; nor has the role of daily environmental stressors associated with continued displacement, statelessness, and life in the refugee camps, been thoroughly researched. This cross-sectional study examined: trauma history, daily environmental stressors, and mental health outcomes for 148 Rohingya adults residing in Kutupalong and Nayapara refugee camps in Bangladesh...
June 2017: Transcultural Psychiatry
https://www.readbyqxmd.com/read/28531196/co-inheritance-of-glucose-6-phosphate-dehydrogenase-deficiency-mutations-and-hemoglobin-e-in-a-kachin-population-in-a-malaria-endemic-region-of-southeast-asia
#3
Zeshuai Deng, Fang Yang, Yao Bai, Lijun He, Qing Li, Yanrui Wu, Lan Luo, Hong Li, Limei Ma, Zhaoqing Yang, Yongshu He, Liwang Cui
Glucose-6-phosphate dehydrogenase (G6PD) deficiency and hemoglobin E (HbE, β26 Glu-Lys) are two common red cell disorders in Southeast Asia. G6PD deficiency produces hemolytic anemia, which can be triggered by certain drugs or infections. HbE is asymptomatic or is manifested as microcytic, minimally hemolytic anemia. The association between G6PD deficiency and HbE is little understood. This study aimed to investigate G6PD deficiency and HbE in a Kachin ethnic group in the China-Myanmar border area. G6PD enzyme activity was measured using a quantitative G6PD assay, G6PD variants genotyped by the SNaPshot assay, and an HbE gene mutation identified by an amplification refractory mutation system and subsequently confirmed by using a reverse dot blot hybridization assay from 100 unrelated individuals in the study area...
2017: PloS One
https://www.readbyqxmd.com/read/28530163/gastrointestinal-histoplasmosis-a-case-series
#4
Rashi Sharma, Lipika Lipi, Smeeta Gajendra, Ishani Mohapatra, Ruchika K Goel, Rajan Duggal, Smruti Ranjan Mishra, Dheeraj Gautam
Histoplasmosis is an invasive mycosis caused by inhalation of the spores of dimorphic fungi Histoplasma capsulatum. The disease manifests in the lung as acute or chronic pulmonary histoplasmosis and in severe cases gets disseminated in multiple organs like skin, adrenal gland, central nervous system, lymph node, liver, spleen, bone marrow, and gastrointestinal tract. It occurs most commonly in immunodeficient patients like HIV-positive patients and transplant recipients, while immunocompetent hosts are affected rarely...
May 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28526661/the-parasol-protocol-an-implementation-science-study-of-hiv-continuum-of-care-interventions-for-gay-men-and-transgender-women-in-burma-myanmar
#5
Andrea L Wirtz, Soe Naing, Emily Clouse, Kaung Htet Thu, Sandra Hsu Hnin Mon, Zin Min Tun, Stefan Baral, Aung Zayar Paing, Chris Beyrer
BACKGROUND: Efforts to improve HIV diagnosis and antiretroviral therapy (ART) initiation among people living with HIV and reduce onward transmission of HIV rely on innovative interventions along multiple steps of the HIV care continuum. These innovative methods are particularly important for key populations, including men who have sex with men (MSM) and transgender women (TW). The HIV epidemic in Myanmar is concentrated among key populations, and national efforts now focus on reducing stigma and improving engagement of MSM and TW in HIV prevention and care...
May 17, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28520726/losing-a-jewel-rapid-declines-in-myanmar-s-intact-forests-from-2002-2014
#6
Tejas Bhagwat, Andrea Hess, Ned Horning, Thiri Khaing, Zaw Min Thein, Kyaw Moe Aung, Kyaw Htet Aung, Paing Phyo, Ye Lin Tun, Aung Htat Oo, Anthony Neil, Win Myo Thu, Melissa Songer, Katherine LaJeunesse Connette, Asja Bernd, Qiongyu Huang, Grant Connette, Peter Leimgruber
New and rapid political and economic changes in Myanmar are increasing the pressures on the country's forests. Yet, little is known about the past and current condition of these forests and how fast they are declining. We mapped forest cover in Myanmar through a consortium of international organizations and environmental non-governmental groups, using freely-available public domain data and open source software tools. We used Landsat satellite imagery to assess the condition and spatial distribution of Myanmar's intact and degraded forests with special focus on changes in intact forest between 2002 and 2014...
2017: PloS One
https://www.readbyqxmd.com/read/28518029/influenza-a-h9n2-virus-myanmar-2014-2015
#7
Thant Nyi Lin, Nutthawan Nonthabenjawan, Supassama Chaiyawong, Napawan Bunpapong, Supanat Boonyapisitsopa, Taveesak Janetanakit, Pont Pont Mon, Hla Hla Mon, Kyaw Naing Oo, Sandi Myint Oo, Mar Mar Win, Alongkorn Amonsin
Routine surveillance of influenza A virus was conducted in Myanmar during 2014-2015. Influenza A(H9N2) virus was isolated in Shan State, upper Myanmar. Whole-genome sequencing showed that H9N2 virus from Myanmar was closely related to H9N2 virus of clade 4.2.5 from China.
June 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28514968/further-evaluation-of-the-nwf-filter-for-the-purification-of-plasmodium-vivax-infected-erythrocytes
#8
Jiangyan Li, Zhiyong Tao, Qian Li, Awtum Brashear, Ying Wang, Hui Xia, Qiang Fang, Liwang Cui
BACKGROUND: Isolation of Plasmodium-infected red blood cells (iRBCs) from clinical blood samples is often required for experiments, such as ex vivo drug assays, in vitro invasion assays and genome sequencing. Current methods for removing white blood cells (WBCs) from malaria-infected blood are time-consuming or costly. A prototype non-woven fabric (NWF) filter was developed for the purification of iRBCs, which showed great efficiency for removing WBCs in a pilot study. Previous work was performed with prototype filters optimized for processing 5-10 mL of blood...
May 17, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28514959/prevention-of-postpartum-haemorrhage-by-community-based-auxiliary-midwives-in-hard-to-reach-areas-of-myanmar-a-qualitative-inquiry-into-acceptability-and-feasibility-of-task-shifting
#9
Kyu Kyu Than, Yasmin Mohamed, Victoria Oliver, Theingi Myint, Thazin La, James G Beeson, Stanley Luchters
BACKGROUND: In Myanmar, postpartum haemorrhage is the leading cause of maternal mortality and contributes to around 30% of all maternal deaths. The World Health Organization recommends training and supporting auxiliary midwives to administer oral misoprostol for prevention of postpartum haemorrhage in resource-limited settings. However, use of misoprostol by auxiliary midwives has not formally been approved in Myanmar. Our study aimed to explore community and provider perspectives on the roles of auxiliary midwives and community-level provision of oral misoprostol by auxiliary midwives...
May 17, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28513386/-working-with-nurses-in-myanmar-opened-my-eyes
#10
Jacqui Thornton
When paediatric nurse Jennifer Sims decided in 2015 that she wanted to take on a new career challenge overseas, she got more than she bargained for.
May 17, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28510203/begonia-myanmarica-begoniaceae-a-new-species-from-myanmar-and-molecular-phylogenetics-of-begonia-sect-monopteron
#11
Yu-Hsin Tseng, Young-Dong Kim, Ching-I Peng, Khin Myo Htwe, Seong-Hyun Cho, Yoshiko Kono, Kuo-Fang Chung
BACKGROUND: A new species, Begonia myanmarica, was discovered from Myanmar and herein documented. Characterized by a single developed wing in the ovary/fruit, this species would be assigned to sect. Monopteron (sensu Doorenbos et al. in The sections of Begonia including descriptions, keys and species lists: studies in Begoniaceae VI. Wageningen Agricultural University, Wageningen, 1998) that is known by B. griffithiana and B. nepalensis from the Himalaya. To confirm its sectional assignment, we conducted morphological, phylogenetic and cytological studies...
December 2017: Botanical Studies (Taipei, Taiwan)
https://www.readbyqxmd.com/read/28506903/ethnozoological-assessment-of-animals-used-by-mon-traditional-medicine-vendors-at-kyaiktiyo-myanmar
#12
Vincent Nijman, Chris R Shepherd
ETHNOPHARMACOLOGICAL RELEVANCE: Wild animals are widely used in traditional Asian medicine but information from Myanmar is lacking. We show that a wide range of animals are used at a pilgrimage site, mostly for their rendered fats and oils to be used in mixed concoctions. The majority of species were sold to be used to treat aching joints, muscle ache and skin diseases. AIM OF THE STUDY: To assess wildlife for sale for medicinal purposes, and document their medicinal use at Kyaiktiyo, a pilgrimage site at a 1100m tall mountain, with many of the pilgrims climbing to the top...
May 12, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28506241/socio-demographic-determinants-of-toxoplasma-gondii-seroprevalence-in-migrant-workers-of-peninsular-malaysia
#13
Norhidayu Sahimin, Yvonne A L Lim, Farnaza Ariffin, Jerzy M Behnke, Maria-Gloria Basáñez, Martin Walker, John W Lewis, Rahmah Noordin, Khairul Anuar Abdullah, Siti Nursheena Mohd Zain
BACKGROUND: The number of migrants working in Malaysia has increased sharply since the 1970's and there is concern that infectious diseases endemic in other (e.g. neighbouring) countries may be inadvertently imported. Compulsory medical screening prior to entering the workforce does not include parasitic infections such as toxoplasmosis. Therefore, this study aimed to evaluate the seroprevalence of T. gondii infection among migrant workers in Peninsular Malaysia by means of serosurveys conducted on a voluntary basis among low-skilled and semi-skilled workers from five working sectors, namely, manufacturing, food service, agriculture and plantation, construction and domestic work...
May 15, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28504441/vector-bionomics-and-malaria-transmission-along-the-thailand-myanmar-border-a-baseline-entomological-survey
#14
N Kwansomboon, V Chaumeau, P Kittiphanakun, D Cerqueira, V Corbel, T Chareonviriyaphap
Baseline entomological surveys were conducted in four sentinel sites along the Thailand-Myanmar border to address vector bionomics and malaria transmission in the context of a study on malaria elimination. Adult Anopheles mosquitoes were collected using human-landing catch and cow-bait collection in four villages during the rainy season from May-June, 2013. Mosquitoes were identified to species level by morphological characters and by AS-PCR. Sporozoite indexes were determined on head/thoraces of primary and secondary malaria vectors using real-time PCR...
June 2017: Journal of Vector Ecology: Journal of the Society for Vector Ecology
https://www.readbyqxmd.com/read/28502184/promoting-community-malaria-control-in-rural-myanmar-through-an-active-community-participation-program-using-the-participatory-learning-approach
#15
Chan Nyein Maung, Than Tun Sein, Thaung Hlaing, Kamolnetr Okanurak, Tassanee Silawan, Jaranit Kaewkungwal
INTRODUCTION: Malaria is prevalent in more than 80% of townships in Myanmar. The National Malaria Control Programme (NMCP) has been implementing community-based malaria control programs nationwide. However, these programs are mostly developed and directed by health authorities, while communities are passively involved. This study aimed to increase community participation in malaria control and promote community malaria control knowledge and practice in rural Myanmar. METHODS: A community-based study, which employed a mixed method approach, collecting data quantitatively and qualitatively, was conducted in two rural villages...
April 2017: Rural and Remote Health
https://www.readbyqxmd.com/read/28490972/intensifying-responsiveness-towards-neglected-intestinal-helminth-infections-in-a-resource-constrained-setting
#16
Khin Thet Wai, Kay Thwe Han, Tin Oo
Neglected intestinal helminth infections afflict the marginalized communities in Asia. Since 2004, growing body of evidence in Myanmar indicated high prevalence of soil-transmitted helminths (STH) infections (30-40%) among school children. Co-existence of STH (23%) with food-borne trematodes was noted among 383 pregnant women in a selected township in 2012-2014 followed by molecular verification of very low prevalence of schistosome infection (<5%) in the same study site in 2016. The success of transmission elimination plans may depend upon sensitive diagnostic tools to detect persistent infections and polyparasitism...
2017: Tropical Medicine and Health
https://www.readbyqxmd.com/read/28490508/longer-exposure-to-a-new-refugee-food-ration-is-associated-with-reduced-prevalence-of-small-for-gestational-age-results-from-2-cross-sectional-surveys-on-the-thailand-myanmar-border
#17
Verena I Carrara, Wolfgang Stuetz, Sue J Lee, Kanlaya Sriprawat, Basi Po, Borimas Hanboonkunupakarn, François H Nosten, Rose McGready
Background: Despite the high risk of compromised nutrition, evidence of the effect of refugee rations on fetal growth is limited. A new ration containing micronutrient-fortified flour without increased caloric content of the general food basket was introduced to the Maela refugee camp in Thailand, July 2004.Objective: The effect of the length of gestational exposure of the new ration on fetal growth was compared with birth outcomes [small for gestational age (SGA), preterm birth (PTB)].Design: In an observational study in 987 newborns from 1048 prospectively followed antenatal clinic (ANC) attendees enrolled in 2 cross-sectional surveys, exposure was categorized in 2004 according to gestation at the time of commencing the new ration and in 2006 as comprehensive (preconception and pregnancy)...
May 10, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28486979/mediation-of-the-effect-of-malaria-in-pregnancy-on-stillbirth-and-neonatal-death-in-an-area-of-low-transmission-observational-data-analysis
#18
Kerryn A Moore, Freya J I Fowkes, Jacher Wiladphaingern, Nan San Wai, Moo Kho Paw, Mupawjay Pimanpanarak, Verena I Carrara, Jathee Raksuansak, Julie A Simpson, Nicholas J White, François Nosten, Rose McGready
BACKGROUND: Malaria in pregnancy is preventable and contributes significantly to the estimated 5.5 million stillbirths and neonatal deaths that occur annually. The contribution of malaria in pregnancy in areas of low transmission has not been quantified, and the roles of maternal anaemia, small-for-gestational-age status, and preterm birth in mediating the effect of malaria in pregnancy on stillbirth and neonatal death are poorly elucidated. METHODS: We analysed observational data routinely collected at antenatal clinics on the Thai-Myanmar border (1986-2015)...
May 10, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28483087/suicidal-behaviors-and-associated-factors-among-university-students-in-six-countries-in-the-association-of-southeast-asian-nations-asean
#19
Karl Peltzer, Siyan Yi, Supa Pengpid
A large data gap remains on suicidal behaviors among youth in the Association of Southeast Asian Nations (ASEAN) countries, despite the increasing rates of suicide in Asian cultures that may be related to rapid economic changes and the loss of social stability. This study was therefore conducted to explore the prevalence of and factors associated with suicidal ideation and suicide attempts among university students in six ASEAN member states. Data were collected in a cross-sectional survey of 4675 undergraduate university students, mean age 20...
April 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28482847/gender-difference-in-early-initiation-of-methamphetamine-use-among-current-methamphetamine-users-in-muse-northern-shan-state-myanmar
#20
Yu Mon Saw, Thu Nandar Saw, Junko Yasuoka, Nyein Chan, Nang Pann Ei Kham, Wint Khine, Su Myat Cho, Masamine Jimba
BACKGROUND: Globally, methamphetamine (MA) use is a significant public health concern due to unprecedented health effects of its use. However, gender similarities and differences in early age of MA initiation and its risk factors among current MA users have been understudied in a developing country setting. METHODS: A community-based, cross-sectional study was conducted using a computer assisted self-interviewing program from January to March 2013 in Muse, Northern Shan State, Myanmar...
May 8, 2017: Harm Reduction Journal
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