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https://www.readbyqxmd.com/read/27922196/hiv-prevalence-and-phylogenetic-characteristics-among-entry-travelers-in-xishuangbanna-prefecture-yunnan-province-between-2003-and-2012
#1
Binghui Wang, Yaobo Liang, Yajuan Wang, Yue Feng, Yaping Li, Li Zhang, Qicai Xuan, Jing Miao, Weihong Qin, Xueshan Xia
Xishuangbanna is a popular tourist destination in southern Yunnan Province, bordering with Vietnam and Laos and Myanmar. There are more than 2 million cross-border travelers annually entering China at two land ports, Daluo and Mohan. To clarify the characteristics of HIV-1 prevalence among entry travelers, a retrospective epidemic investigation was conducted. Between 2003 and 2012, 196 among 91,432 entry travelers were detected to be HIV-1-positive, accounting for infection rate of 0.21%. Eighty-one gag-pol gene sequences were obtained for phylogenetic analyses and subsequent recombination analysis...
December 6, 2016: Journal of Medical Virology
https://www.readbyqxmd.com/read/27920482/hepatitis-c-virus-therapy-with-peg-interferon-and-ribavirin-in-myanmar-a-resource-constrained-country
#2
Naomi Khaing Than Hlaing, Debolina Banerjee, Robert Mitrani, Soe Htet Arker, Kyaw San Win, Nyan Lin Tun, Zaw Thant, Khin Maung Win, K Rajender Reddy
AIM: To investigate peg-interferon (peg-IFN) and ribavirin (RBV) therapy in Myanmar and to predict sustained virologic response (SVR). METHODS: This single-center, open-label, study was conducted in Myanmar between 2009 and 2014. A total of 288 patients infected with HCV genotypes 1, 2, 3 and 6 were treated with peg-IFN alpha-2a (180 μg/wk) or alpha-2b (50 to 100 μg as a weight-based dose) and RBV as a weight-based dose (15 mg/kg/d). Treatment duration was 48 wk for genotypes 1 and 6, 24 wk for genotype 2, and 24 or 48 wk for genotype 3 based on rapid virologic response (RVR)...
November 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27920241/effectiveness-of-mindfulness-intervention-on-psychological-behaviors-among-adolescents-with-parental-hiv-infection-a-group-randomized-controlled-trial
#3
Myo-Myo Mon, Tippawan Liabsuetrakul, Kyaw-Min Htut
This study aims to identify the effectiveness of mindfulness intervention on the psychological behaviors of adolescents with parental HIV infection and its associated factors in Myanmar. A total of 80 adolescents from 2 intervention townships and 80 adolescents from 2 control townships were enrolled in a group randomized controlled trial with assessments at baseline and 6 months follow-up. The mindfulness intervention involved monthly group sessions for 3 consecutive months led by an experienced mindfulness trainer...
November 2016: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/27920239/the-regional-comprehensive-economic-partnership-intellectual-property-protection-and-access-to-medicines
#4
Belinda Townsend, Deborah Gleeson, Ruth Lopert
The inclusion of elevated standards of intellectual property (IP) protection in the recently negotiated Trans-Pacific Partnership (TPP) agreement has raised serious public health concerns regarding access to medicines. A lesser-known trade agreement under negotiation in the Asia-Pacific region is the Regional Comprehensive Economic Partnership (RCEP). Framed as an attempt to reassert ASEAN's position in response to the United States-led TPP, RCEP includes key players China and India as well as several low- and middle-income countries (LMICs)...
November 2016: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/27919892/significant-divergence-in-sensitivity-to-antimalarial-drugs-between-neighboring-plasmodium-falciparum-populations-along-the-eastern-border-of-myanmar
#5
Weilin Zeng, Yao Bai, Meilian Wang, Zenglei Wang, Shuang Deng, Yonghua Ruan, Shi Feng, Zhaoqing Yang, Liwang Cui
Malaria parasites in different endemic areas display different levels of resistance to antimalarial drugs as the result of varied drug use histories. To provide updated knowledge of drug sensitivities during the malaria elimination phase in Southeast Asia, an epicenter of multidrug resistance, we determined in vitro susceptibilities of culture-adapted Plasmodium falciparum isolates from two eastern border regions (Wa and Kachin) of Myanmar to ten drugs. Despite their close proximity, the Kachin parasites displayed higher IC50 values than the Wa parasites to chloroquine, piperaquine, naphthoquine, mefloquine, quinine, pyrimethamine, pyronaridine, lumefantrine and dihydroartemisinin...
December 5, 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/27919289/correlates-of-sex-trading-among-male-non-injecting-drug-users-in-myanmar-a-cross-sectional-study
#6
Yu Mon Saw, Thu Nandar Saw, Kyi Mar Wai, Krishna C Poudel, Hla Hla Win
BACKGROUND: Sex trading is a recognized risk factor for human immune deficiency virus infection and other sexually transmitted infections among non-injecting drug users (NIDUs). However, very little research has addressed the factors associated with sex trading among male NIDUs in Myanmar. METHODS: A cross-sectional study was conducted from January to February 2010 using the respondent-driven sampling method. In total, 210 NIDUs aged between 18 and 49 years, with no history of injecting drug use, and who used non-injected illicit drugs in the last 6 months were recruited...
December 5, 2016: Harm Reduction Journal
https://www.readbyqxmd.com/read/27919240/urban-rural-differences-in-the-prevalence-of-non-communicable-diseases-risk-factors-among-25-74-years-old-citizens-in-yangon-region-myanmar-a-cross-sectional-study
#7
Aung Soe Htet, Marius B Bjertness, Lhamo Y Sherpa, Marte Karoline Kjøllesdal, Win Myint Oo, Haakon E Meyer, Hein Stigum, Espen Bjertness
BACKGROUND: Recent societal and political reforms in Myanmar may upturn the socio-economy and, thus, contribute to the country's health transition. Baseline data on urban-rural disparities in non-communicable disease (NCD) risk factors are not thoroughly described in this country which has been relatively closed for more than five decades. We aim to investigate urban-rural differences in mean values and the prevalence of selected behavioral and metabolic risk factors for non-communicable diseases and 10-years risk in development of coronary heart diseases (CHD)...
December 5, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27918837/global-pulses-scenario-status-and-outlook
#8
P K Joshi, P Parthasarathy Rao
Although pulse production grew significantly by 1.3% between 1980 and 2013, its per capita availability remained stagnant at around 6.5 kg/capita/year. In 1961, its availability was 9.3 kg/capita/year. One consequence of slower growth in its production is rising pulse prices, which are twice that of cereals. The declining availability of pulses also triggered a boom in its trade, with 19% of the global pulse production traded in 2011 compared with 7% in 1980. In absolute terms, there has been a more than fourfold increase in pulse trade, compared with an only 1...
December 5, 2016: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/27916235/the-rohingya-people-of-myanmar-health-human-rights-and-identity
#9
REVIEW
Syed S Mahmood, Emily Wroe, Arlan Fuller, Jennifer Leaning
The Rohingya people of Myanmar (known as Burma before 1989) were stripped of citizenship in 1982, because they could not meet the requirement of proving their forefathers settled in Burma before 1823, and now account for one in seven of the global population of stateless people. Of the total 1·5 million Rohingya people living in Myanmar and across southeast Asia, only 82 000 have any legal protection obtained through UN-designated refugee status. Since 2012, more than 159 000 people, most of whom are Rohingya, have fled Myanmar in poorly constructed boats for journeys lasting several weeks to neighbouring nations, causing hundreds of deaths...
December 1, 2016: Lancet
https://www.readbyqxmd.com/read/27912758/emerging-polymorphisms-in-falciparum-kelch-13-gene-in-northeastern-region-of-india
#10
Neelima Mishra, Ram Suresh Bharti, Prashant Mallick, Om Prakash Singh, Bina Srivastava, Roma Rana, Sobhan Phookan, Hardev Prasad Gupta, Pascal Ringwald, Neena Valecha
BACKGROUND: Recent reports of emergence and spread of artemisinin resistance in the Southeast Asia region, including Myanmar, pose a greater threat to malaria control and elimination in India. Whole genome sequencing studies have associated mutations in the K13 propeller gene (k13), PF3D7_1343700 with artemisinin resistance both in vitro and in vivo. The aim of the present study was to find the k13 gene polymorphisms in Plasmodium falciparum parasites from the three sites in the Northeast region of India, bordering Bangladesh and Myanmar...
December 3, 2016: Malaria Journal
https://www.readbyqxmd.com/read/27909349/spatiotemporal-patterns-and-trends-of-indian-monsoonal-rainfall-extremes
#11
Nishant Malik, Bodo Bookhagen, Peter J Mucha
In this study, we provide a comprehensive analysis of trends in the extremes during the Indian summer monsoon (ISM) months (June to September) at different temporal and spatial scales. Our goal is to identify and quantify spatiotemporal patterns and trends that have emerged during the recent decades and may be associated with changing climatic conditions. Our analysis primarily relies on quantile regression that avoids making any subjective choices on spatial, temporal, or intensity pattern of extreme rainfall events...
February 28, 2016: Geophysical Research Letters
https://www.readbyqxmd.com/read/27903054/future-malaria-spatial-pattern-based-on-the-potential-global-warming-impact-in-south-and-southeast-asia
#12
Hassan M Khormi, Lalit Kumar
We used the Model for Interdisciplinary Research on Climate-H climate model with the A2 Special Report on Emissions Scenarios for the years 2050 and 2100 and CLIMEX software for projections to illustrate the potential impact of climate change on the spatial distributions of malaria in China, India, Indochina, Indonesia, and The Philippines based on climate variables such as temperature, moisture, heat, cold and dryness. The model was calibrated using data from several knowledge domains, including geographical distribution records...
November 21, 2016: Geospatial Health
https://www.readbyqxmd.com/read/27899135/analysis-of-pvama1-genes-from-china-myanmar-border-reveals-little-regional-genetic-differentiation-of-plasmodium-vivax-populations
#13
Xiaotong Zhu, Pan Zhao, Si Wang, Fei Liu, Jun Liu, Jian Wang, Zhaoqing Yang, Guiyun Yan, Qi Fan, Yaming Cao, Liwang Cui
BACKGROUND: With the premise of diminishing parasite genetic diversity following the reduction of malaria incidence, the analysis of polymorphic antigenic markers may provide important information about the impact of malaria control on local parasite populations. Here we evaluated the genetic diversity of Plasmodium vivax apical membrane antigen 1 (Pvama1) gene in a parasite population from the China-Myanmar border and compared it with global P. vivax populations. METHODS: We performed evolutionary analysis to examine the genetic diversity, natural selection, and population differentiation of 73 Pvama1 sequences acquired from the China-Myanmar border as well as 615 publically available Pvama1 sequences from seven global P...
November 29, 2016: Parasites & Vectors
https://www.readbyqxmd.com/read/27894299/evolutionary-phylodynamics-of-foot-and-mouth-disease-virus-serotypes-o-and-a-circulating-in-vietnam
#14
Van Phan Le, Thi Thu Hang Vu, Hong-Quan Duong, Van Thai Than, Daesub Song
BACKGROUND: Foot-and-mouth disease virus (FMDV) is one of the highest risk factors that affects the animal industry of the country. The virus causes production loss and high ratio mortality in young cloven-hoofed animals in Vietnam. The VP1 coding gene of 80 FMDV samples (66 samples of the serotype O and 14 samples of the serotype A) collected from endemic outbreaks during 2006-2014 were analyzed to investigate their phylogeny and genetic relationship with other available FMDVs globally...
November 29, 2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27890089/a-mid-cretaceous-eccrinales-infesting-a-primitive-wasp-in-myanmar-amber
#15
George Poinar
A mid-Cretaceous Eccrinales in Myanmar amber is described as Paleocadus burmiticus gen. et sp. nov. in the family Eccrinaceae. The fossil is represented by two types of sporangiospores formed on different thalli protruding from the anus of a primitive wasp, with secondary infestation spores multinucleate and thin walled. Its presence establishes the Eccrinales in the mid-Cretaceous and shows that at that time, lineages of this group parasitized wasps, an association unknown with extant members of the Order.
December 2016: Fungal Biology
https://www.readbyqxmd.com/read/27887652/limitations-of-malaria-reactive-case-detection-in-an-area-of-low-and-unstable-transmission-on-the-myanmar-thailand-border
#16
Daniel M Parker, Jordi Landier, Lorenz von Seidlein, Arjen Dondorp, Lisa White, Borimas Hanboonkunupakarn, Richard J Maude, François H Nosten
BACKGROUND: Reactive case detection is an approach that has been proposed as a tool for malaria elimination in low-transmission settings. It is an intuitively justified approach based on the concept of space-time clustering of malaria cases. When an index malaria clinical case is detected, it triggers reactive screening and treatment in the index house and neighbouring houses. However, the efficacy of this approach at varying screening radii and malaria prevalence remains ill defined...
November 25, 2016: Malaria Journal
https://www.readbyqxmd.com/read/27886939/development-and-implementation-of-models-of-care-for-musculoskeletal-conditions-in-middle-income-and-low-income-asian-countries
#17
REVIEW
Keith K Lim, Madelynn Chan, Sandra Navarra, Syed Atiqul Haq, Chak Sing Lau
This chapter discusses the challenges faced in the development and implementation of musculoskeletal (MSK) Models of Care (MoCs) in middle-income and low-income countries in Asia and outlines the components of an effective MoC for MSK conditions. Case studies of four such countries (The Philippines, Malaysia, Bangladesh and Myanmar) are presented, and their unique implementation issues are discussed. The success experienced in one high-income country (Singapore) is also described as a comparison. The Community Oriented Program for Control of Rheumatic Diseases (COPCORD) project and the role of Asia Pacific League of Associations for Rheumatology (APLAR), a professional body supporting MoC initiatives in this region, are also discussed...
June 2016: Best Practice & Research. Clinical Rheumatology
https://www.readbyqxmd.com/read/27876918/report-of-amblyomma-testudinarium-in-mithuns-bos-frontalis-from-eastern-mizoram-india
#18
J K Chamuah, K Bhattacharjee, P C Sarmah, O K Raina, S Mukherjee, C Rajkhowa
Physical examination of semi-domesticated, free ranging mithuns (Bos frontalis) during an animal health check-up and treatment camp organized at Khuwangleng village in the Champhai district of Mizoram, India and adjacent to Myanmar Border revealed presence of unusually large blood engorged ticks attaching to the dewlap and inner aspects of thighs. On the basis of morphological study, the ticks were found indistinguishable from female Amblyomma testudinarium. Prevalence rate of the tick species in mithuns living in the forests was 9...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27866919/in-vitro-sensitivity-of-antimalarial-drugs-and-correlation-with-clinico-parasitological-response-following-treatment-with-a-3-day-artesunate-mefloquine-combination-in-patients-with-falciparum-malaria-along-the-thai-myanmar-border
#19
Phunuch Muhamad, Artitaya Thiengsusuk, Papichaya Phompradit, Kesara Na-Bangchang
A 3-day artesunate-mefloquine combination therapy has been using as first-line treatment for acute uncomplicated Plasmodium falciparum malaria in Thailand since 1995 on the background of mefloquine resistance. The aim of the present study was to assess sensitivity of P. falciparum isolates (n=44) in an area along the Thai-Myanmar border (year 2009) to artesunate, mefloquine, chloroquine and quinine, including their correlation with clinico-parasitological response. Twenty, 19, and 5 isolates were collected from patients with 'Adequate Clinical and Parasitological Response (ACPR)', 'Late Parasitological Failure (LPF)' and 're-infection', respectively...
November 17, 2016: Acta Tropica
https://www.readbyqxmd.com/read/27856484/leprosy-post-exposure-prophylaxis-lpep-programme-study-protocol-for-evaluating-the-feasibility-and-impact-on-case-detection-rates-of-contact-tracing-and-single-dose-rifampicin
#20
Tanja Barth-Jaeggi, Peter Steinmann, Liesbeth Mieras, Wim van Brakel, Jan Hendrik Richardus, Anuj Tiwari, Martin Bratschi, Arielle Cavaliero, Bart Vander Plaetse, Fareed Mirza, Ann Aerts
INTRODUCTION: The reported number of new leprosy patients has barely changed in recent years. Thus, additional approaches or modifications to the current standard of passive case detection are needed to interrupt leprosy transmission. Large-scale clinical trials with single dose rifampicin (SDR) given as post-exposure prophylaxis (PEP) to contacts of newly diagnosed patients with leprosy have shown a 50-60% reduction of the risk of developing leprosy over the following 2 years. To accelerate the uptake of this evidence and introduction of PEP into national leprosy programmes, data on the effectiveness, impact and feasibility of contact tracing and PEP for leprosy are required...
November 17, 2016: BMJ Open
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