keyword
MENU ▼
Read by QxMD icon Read
search

APECED

keyword
https://www.readbyqxmd.com/read/28615126/unveiling-the-participation-of-avian-kinin-ornithokinin-and-its-receptors-in-the-chicken-inflammatory-response
#1
Rodrigo Guabiraba, Damien Garrido, Geoffrey Bailleul, Angélina Trotereau, Mélanie Pinaud, Anne-Christine Lalmanach, Nathalie K Chanteloup, Catherine Schouler
Vasoactive peptides are key early mediators of inflammation released through activation of different enzymatic systems. The mammalian kinin-kallikrein (K-KLK) system produces bradykinin (BK) through proteolytic cleavage of a kininogen precursor by enzymes named kallikreins. BK acts through specific ubiquitous G-protein coupled receptors (B1R and B2R) to participate in physiological processes and inflammatory responses, such as activation of mononuclear phagocytes. In chickens, the BK-like nonapeptide ornithokinin (OK) has been shown to promote intracellular calcium increase in embryonic fibroblasts and to be vasodilatory in vivo...
June 2017: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/28599670/whole-genome-sequencing-of-an-expec-that-caused-fatal-pneumonia-at-a-pig-farm-in-changchun-china
#2
Ling-Cong Kong, Xia Guo, Zi Wang, Yun-Hang Gao, Bo-Yan Jia, Shu-Ming Liu, Hong-Xia Ma
BACKGROUND: In recent years, highly frequent swine respiratory diseases have been caused by extraintestinal pathogenic Escherichia coli (ExPEC) in China. Due to this increase in ExPECs, this bacterial pathogen has become a threat to the development of the Chinese swine industry. To investigate ExPEC pathogenesis, we isolated a strain (named SLPE) from lesioned porcine lungs from Changchun in China, reported the draft genome and performed comparative genomic analyses. RESULTS: Based on the gross post-mortem examination, bacterial isolation, animal regression test and 16S rRNA gene sequence analysis, the pathogenic bacteria was identified as an ExPEC...
June 9, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28594893/pandemic-extra-intestinal-pathogenic-escherichia-coli-expec-clonal-group-o6-b2-st73-as-a-cause-of-avian-colibacillosis-in-brazil
#3
Marcos Paulo Vieira Cunha, Andre Becker Saidenberg, Andrea Micke Moreno, Antonio José Piantino Ferreira, Mônica Aparecida Midolli Vieira, Tânia Aparecida Tardelli Gomes, Terezinha Knöbl
Extra-intestinal pathogenic Escherichia coli (ExPEC) represent an emerging pathogen, with pandemic strains increasingly involved in cases of urinary tract infections (UTIs), bacteremia, and meningitis. In addition to affecting humans, the avian pathotype of ExPEC, avian pathogenic E. coli (APEC), causes severe economic losses to the poultry industry. Several studies have revealed overlapping characteristics between APEC and human ExPEC, leading to the hypothesis of a zoonotic potential of poultry strains. However, the description of certain important pandemic clones, such as Sequence Type 73 (ST73), has not been reported in food sources...
2017: PloS One
https://www.readbyqxmd.com/read/28567288/gad-antibody-associated-limbic-encephalitis-in-a-young-woman-with-apeced
#4
Anna Kopczak, Adrian-Minh Schumacher, Sandra Nischwitz, Tania Kümpfel, Günter K Stalla, Matthias K Auer
The autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) syndrome is a genetic disorder caused by a mutation in the autoimmune regulator (AIRE) gene. Immune deficiency, hypoparathyroidism and Addison's disease due to autoimmune dysfunction are the major clinical signs of APECED. We report on a 21-year-old female APECED patient with two inactivating mutations in the AIRE gene. She presented with sudden onset of periodic nausea. Adrenal insufficiency was diagnosed by means of the ACTH stimulation test...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/28536675/an-overview-of-two-component-signal-transduction-systems-implicated-in-extra-intestinal-pathogenic-e-coli-infections
#5
REVIEW
Erin J Breland, Allison R Eberly, Maria Hadjifrangiskou
Extra-intestinal pathogenic E. coli (ExPEC) infections are common in mammals and birds. The predominant ExPEC types are avian pathogenic E. coli (APEC), neonatal meningitis causing E. coli/meningitis associated E. coli (NMEC/MAEC), and uropathogenic E. coli (UPEC). Many reviews have described current knowledge on ExPEC infection strategies and virulence factors, especially for UPEC. However, surprisingly little has been reported on the regulatory modules that have been identified as critical in ExPEC pathogenesis...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28496941/chromosomal-features-of-escherichia-coli-serotype-o2-k2-an-avian-pathogenic-e-coli
#6
Steffen L Jørgensen, Egle Kudirkiene, Lili Li, Jens P Christensen, John E Olsen, Lisa Nolan, Rikke H Olsen
Escherichia coli causing infection outside the gastrointestinal system are referred to as extra-intestinal pathogenic E. coli. Avian pathogenic E. coli is a subgroup of extra-intestinal pathogenic E. coli and infections due to avian pathogenic E. coli have major impact on poultry production economy and welfare worldwide. An almost defining characteristic of avian pathogenic E. coli is the carriage of plasmids, which may encode virulence factors and antibiotic resistance determinates. For the same reason, plasmids of avian pathogenic E...
2017: Standards in Genomic Sciences
https://www.readbyqxmd.com/read/28479276/viability-assessment-of-ascaris-suum-eggs-stained-with-fluorescent-dyes-using-digital-colorimetric-analysis
#7
Magdalena Włodarczyk, Jolanta Zdybel, Marek Próchniak, Zbigniew Osiński, Jacek Karamon, Teresa Kłapeć, Tomasz Cencek
The aim of the study was to develop a method for the colorimetric evaluation of nematode eggs using appropriate instruments. The materials for the study were live and dead (inactivated) eggs of the Ascaris suum. Viability of the eggs was assessed using four different kits for fluorescent staining (for each technique, a series of photos were taken). Images of stained eggs were analysed using graphic software with RGB (red-green-blue) function. The viability of the eggs was assessed according to the relative positions of the distributions of colour intensities of live or dead eggs - distributions area's overlap index (DAOI), and distributions area's separation index (DASI) were calculated...
May 4, 2017: Experimental Parasitology
https://www.readbyqxmd.com/read/28473898/phylogenetic-typing-and-molecular-detection-of-virulence-factors-of-avian-pathogenic-escherichia-coli-isolated-from-colibacillosis-cases-in-japanese-quail
#8
Hesam Alizade, Reza Ghanbarpour, Maziar Jajarami, Asma Askari
Colibacillosis caused by avian pathogenic Escherichia coli (APEC) is an economic threat to the poultry industry throughout the world. Some of the virulence genes may enhance the ability of E. coli isolates to grow in the tissues of broilers. The APEC strains are assigned to a few distinct phylogenetic groups. The purpose of the present study was to detect the virulence genes and phylogenetic groups of E. coli isolates from colibacillosis cases in Japanese quail in 2014 in Kerman, Iran. In the present study, one hundred and two E...
2017: Veterinary Research Forum
https://www.readbyqxmd.com/read/28458664/childhood-polyarthritis-as-early-manifestation-of-autoimmune-polyendocrinopathy-with-candidiasis-and-ectodermal-dystrophy-syndrome
#9
Maria J Gutierrez, Julieta Gilson, Jamie Zacharias, Faoud Ishmael, C April Bingham
Autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED) is a rare disorder of immune dysregulation caused by mutations in the autoimmune regulator (AIRE) gene. Individuals affected with APECED develop a clinical syndrome characterized by ectodermal abnormalities, autoantibody production, and organ-specific autoimmune manifestations. Inflammatory arthritis is usually not described as a part of the syndrome, and only sporadic cases are reported. We describe the case of a preschool-age girl who presented with hypoparathyroidism, hepatitis, interstitial pneumonitis, and chronic polyarthritis at 4 years of age and was found to have two compound heterozygous disease-associated mutations in the AIRE gene...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28438362/bypass-of-an-anesthesiologist-directed-preoperative-evaluation-clinic-results-in-greater-first-case-tardiness-and-turnover-times
#10
Richard H Epstein, Franklin Dexter, Eric S Schwenk, Thomas A Witkowski
STUDY OBJECTIVE: We evaluated 4 hypotheses related to bypass of an anesthesiologist-directed preoperative evaluation clinics (APEC): 1) first-case tardiness and turnover times increased; 2) turnover times increased more than first-case tardiness; and higher American Society of Anesthesiologists Physical Status (ASA PS) resulted in both an ordered increase among ASA PS and within ASA PS in 3) first-case tardiness; and 4) turnover times. DESIGN: Retrospective observational study using electronic health records...
April 21, 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28419339/effect-of-chlorine-treatment-on-inhibition-of-e-coli-serogroup-o2-incorporation-into-7-day-old-biofilm-on-polyvinylchloride-surface
#11
P Maharjan, S Dey, G Huff, W Zhang, G K Phillips, S Watkins
Poultry waterlines are constructed using polyvinylchloride (PVC) material on which bacterial biofilm can easily form. Biofilm can harbor pathogens including avian pathogenic E. coli (APEC) strains. An in vitro evaluation was performed to determine if E. coli sero group O2 (avian pathogenic) could attach on a PVC surface that had pre-formed biofilm and if this phenomenon could be affected when water was treated with chlorine. Initially, biofilm growth was induced in PVC test coupons (15.16 cm2) for a 7-day period mimicking the waterline scenario in the first wk of poultry brooding; and then this biofilm was challenged with E...
April 17, 2017: Poultry Science
https://www.readbyqxmd.com/read/28407484/autoreactive-t-cells-and-chronic-fungal-infection-drive-esophageal-carcinogenesis
#12
Feng Zhu, Jami Willette-Brown, Na-Young Song, Dakshayani Lomada, Yongmei Song, Liyan Xue, Zane Gray, Zitong Zhao, Sean R Davis, Zhonghe Sun, Peilin Zhang, Xiaolin Wu, Qimin Zhan, Ellen R Richie, Yinling Hu
Humans with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), a T cell-driven autoimmune disease caused by impaired central tolerance, are susceptible to chronic fungal infection and esophageal squamous cell carcinoma (ESCC). However, the relationship between autoreactive T cells and chronic fungal infection in ESCC development remains unclear. We find that kinase-dead Ikkα knockin mice develop APECED-like phenotypes, including impaired central tolerance, autoreactive T cells, chronic fungal infection, and ESCCs expressing specific human ESCC markers...
April 12, 2017: Cell Host & Microbe
https://www.readbyqxmd.com/read/28398866/genome-wide-survey-of-genes-under-positive-selection-in-avian-pathogenic-escherichia-coli-strains
#13
Thaís Cabrera Galvão Rojas, Francisco Pereira Lobo, Jorge Augusto Hongo, Renato Vicentini, Renu Verma, Renato Pariz Maluta, Wanderley Dias da Silveira
The ability to obtain bacterial genomes from the same host has allowed for comparative studies that help in the understanding of the molecular evolution of specific pathotypes. Avian pathogenic Escherichia coli (APEC) is a group of extraintestinal strains responsible for causing colibacillosis in birds. APEC is also suggested to possess a role as a zoonotic agent. Despite its importance, APEC pathogenesis still has several cryptic pathogenic processes that need to be better understood. In this work, a genome-wide survey of eight APEC strains for genes with evidence of recombination revealed that ∼14% of the homologous groups evaluated present signs of recombination...
May 2017: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/28378963/division-of-methods-for-counting-helminths-eggs-and-the-problem-of-efficiency-of-these-methods
#14
Katarzyna Jaromin-Gleń, Teresa Kłapeć, Grzegorz Łagód, Jacek Karamon, Jacek Malicki, Agata Skowrońska, Andrzej Bieganowski
From the sanitary and epidemiological aspects, information concerning the developmental forms of intestinal parasites, especially the eggs of helminths present in our environment in: water, soil, sandpits, sewage sludge, crops watered with wastewater are very important. The methods described in the relevant literature may be classified in various ways, primarily according to the methodology of the preparation of samples from environmental matrices prepared for analysis, and the sole methods of counting and chambers/instruments used for this purpose...
March 21, 2017: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/28376430/characteristics-and-emission-reduction-measures-evaluation-of-pm2-5-during-the-two-major-events-apec-and-parade
#15
Gang Wang, Shuiyuan Cheng, Wei Wei, Xiaowen Yang, Xiaoqi Wang, Jia Jia, Jianlei Lang, Zhe Lv
The measurement of PM2.5 was conducted from 20th October to 25th November 2014, and 15th August to 15th September 2015 at Beijing, Shijiazhuang, and Tangshan, China, covering two important events of Asia-Pacific Economic Cooperation (APEC) and Grand Military Parade (Parade). A series of stringent emission-reduction measures were implemented in Beijing and neighbouring regions to ensure good air quality in Beijing. PM2.5 concentrations and major components (water-soluble ions and carbonaceous aerosol) were analyzed and compared between the two events...
October 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28315387/functional-role-of-ompf-and-ompc-porins-in-pathogenesis-of-avian-pathogenic-escherichia-coli
#16
Hassan M A Hejair, Yinchu Zhu, Jiale Ma, Yue Zhang, Zihao Pan, Wei Zhang, Huochun Yao
Avian pathogenic Escherichia coli is an important pathogen causes systemic infections in avian species and large economic losses in poultry industry worldwide. The functional role of porins during the infection and their mechanisms of interaction with host tissues for adhesion to and invasion are poorly understood. However, whether porins play a role in infection remains unclear. In this study we evaluated the potential of ompF and ompC outer membrane porins in the pathogenesis of avian pathogenic E. coli (APEC) strain TW-XM...
March 14, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28284555/reduction-in-population-exposure-to-pm2-5-and-cancer-risk-due-to-pm2-5-bound-pahs-exposure-in-beijing-china-during-the-apec-meeting
#17
Yangyang Xie, Bin Zhao, Yuejing Zhao, Qinzi Luo, Shuxiao Wang, Bin Zhao, Shunhua Bai
Radical measures for controlling ambient air pollution sources were employed by the Chinese government during the Asia-Pacific Economic Cooperation (APEC) meeting in 2014, providing a unique case to evaluate the health effect benefits from such measures. To examine the cancer risk reduction from the source control measures during the APEC meeting, we estimated the reduction in population exposure to PM2.5 and PAHs and the reduction in PAHs-associated cancer risk if the control measures were sustained over time...
March 8, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28283322/asia-pacific-consensus-guidelines-for-endoscopic-management-of-benign-biliary-strictures
#18
REVIEW
Bing Hu, Bo Sun, Qiang Cai, James Yun Wong Lau, Shuren Ma, Takao Itoi, Jong Ho Moon, Ichiro Yasuda, Xiaofeng Zhang, Hsiu-Po Wang, Shomei Ryozawa, Rungsun Rerknimitr, Wen Li, Hiromu Kutsumi, Sundeep Lakhtakia, Hideyuki Shiomi, Ming Ji, Xun Li, Dongmei Qian, Zhuo Yang, Xiao Zheng
No abstract text is available yet for this article.
March 7, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28280491/comparative-analysis-of-phylogenetic-assignment-of-human-and-avian-expec-and-fecal-commensal-escherichia-coli-using-the-previous-and-revised-clermont-phylogenetic-typing-methods-and-its-impact-on-avian-pathogenic-escherichia-coli-apec-classification
#19
Catherine M Logue, Yvonne Wannemuehler, Bryon A Nicholson, Curt Doetkott, Nicolle L Barbieri, Lisa K Nolan
The Clermont scheme has been used for subtyping of Escherichia coli since it was initially described in early 2000. Since then, researchers have used the scheme to type and sub-type commensal E. coli and pathogenic E. coli, such as extraintestinal pathogenic E. coli (ExPEC), and compare their phylogenetic assignment by pathogenicity, serogroup, distribution among ExPEC of different host species and complement of virulence and resistance traits. Here, we compare assignments of human and avian ExPEC and commensal E...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28270101/deciphering-alternative-splicing-and-nonsense-mediated-decay-modulate-expression-in-primary-lymphoid-tissues-of-birds-infected-with-avian-pathogenic-e-coli-apec
#20
Hongyan Sun
BACKGROUND: Avian pathogenic E. coli (APEC) can lead to a loss in millions of dollars in poultry annually because of mortality and produce contamination. Studies have verified that many immune-related genes undergo changes in alternative splicing (AS), along with nonsense mediated decay (NMD), to regulate the immune system under different conditions. Therefore, the splicing profiles of primary lymphoid tissues with systemic APEC infection need to be comprehensively examined. RESULTS: Gene expression in RNAseq data were obtained for three different immune tissues (bone marrow, thymus, and bursa) from three phenotype birds (non-challenged, resistant, and susceptible birds) at two time points...
March 7, 2017: BMC Genetics
keyword
keyword
92688
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"