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https://www.readbyqxmd.com/read/28925730/impact-of-frequent-interruption-on-nurses-patient-controlled-analgesia-programming-performance
#1
Kristi R Campoe, Karen K Giuliano
OBJECTIVE: The purpose was to add to the body of knowledge regarding the impact of interruption on acute care nurses' cognitive workload, total task completion times, nurse frustration, and medication administration error while programming a patient-controlled analgesia (PCA) pump. BACKGROUND: Data support that the severity of medication administration error increases with the number of interruptions, which is especially critical during the administration of high-risk medications...
September 1, 2017: Human Factors
https://www.readbyqxmd.com/read/28924562/assessment-of-analytical-performance-of-glucose-meter-in-pediatric-age-group-at-tertiary-care-referral-hospital
#2
Mohit Vijay Rojekar, Vandana Kumawat, Jayesh Panot, Surekha Khedkar, Arati Adhe-Rojekar
BACKGROUND: Glucometers are the excellent tools for self-monitoring of blood glucose (SMBG). They are important especially in the circumstances where continuous monitoring is mandatory and at decision making levels. Tight glycemic control protocols are important for preventing the ill effects of fluctuating glucose levels. This increases the use of glucometers in various healthcare settings. As technology advances, glucometers are getting better in terms of quality of results. But still some lacunae are there...
2017: Journal of Diabetes and Metabolic Disorders
https://www.readbyqxmd.com/read/28922317/medical-genetic-services-in-a-developing-country-lesson-from-thailand
#3
Chanin Limwongse
PURPOSE OF REVIEW: To give an example of how advances in medical genetics impact a developing country and how Thailand struggle to improve medical genetics services. RECENT FINDINGS: Thailand is an example of developing country with limited resources, low geneticist to population ratio, formally decentralized even though practically centralized healthcare system and growing public interest in medical genetic technology. Nonetheless, efforts have been and still being made in regard to expanding clinical genetics services, improving access to laboratory diagnosis, increasing rare disease medication in national formulary, and training of medical genetics personnel...
September 16, 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/28911305/alginate-based-cell-microencapsulation-for-tissue-engineering-and-regenerative-medicine
#4
Vittoria Pandolfi, Ulysse Pereira, Murielle Dufresne, Cécile Legallais
Increasing numbers of requests for transplantable organs and their scarcity has led to a pressing need to find alternative solutions to standard transplantation. An appealing but challenging proposal came from the fields of tissue engineering and regenerative medicine, the purpose of which is to build tissues/organs from scratch in the laboratory and use them as either permanent substitutes for direct implantation into the patient's body, or as temporary substitutes to bridge patients until organ regeneration or transplantation...
June 8, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28898986/building-a-new-transfusion-service
#5
John R Hess, Brenda K Hayden, Virginia G Cruz-Cody, Max J Louzon, Erin E Tuott, Nina E Sen, Roxann Gary, Patrick J Ramos, Jennifer A Daniel-Johnson, Ryan A Metcalf, Monica B Pagano
Objectives: For over 60 years, Harborview Medical Center (HMC) in Seattle has received its blood components and pretransfusion testing from a centralized transfusion service operated by the regional blood supplier. In 2011, a hospital-based transfusion service (HBTS) was activated. Methods: After 5 years of operation, we evaluated the effects of the HBTS by reviewing records of hospital blood use, quality system events, blood product delivery times, and costs. Furthermore, the effects of in-house expertise on laboratory medicine resident and medical laboratory scientist student training, as well as regulatory and accrediting agency concerns, were reviewed...
August 1, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28895317/assessment-of-a-noninvasive-optical-photoplethysmography-imaging-device-with-dynamic-tissue-phantom-models
#6
C Ikenna Nwafor, Kevin D Plant, Darlene R King, Brian P McCall, John J Squiers, Wensheng Fan, J Michael DiMaio, Jeffrey E Thatcher
Noncontact photoplethysmography (PPG) has been studied as a method to provide low-cost, noninvasive, two-dimensional blood oxygenation measurements and medical imaging for a variety of near-surface pathologies. To evaluate this technology in a laboratory setting, dynamic tissue phantoms were developed with tunable parameters that mimic physiologic properties of the skin, including blood vessel volume change, pulse wave frequency, and tissue scattering and absorption. Tissue phantoms were generated using an elastic tubing to represent a blood vessel where the luminal volume could be modulated with a pulsatile fluid flow...
September 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/28893193/light-emitting-diode-fluorescent-microscopy-and-xpert-mtb-rif%C3%A2-assay-for-diagnosis-of-pulmonary-tuberculosis-among-patients-attending-ambo-hospital-west-central-ethiopia
#7
Alemu Gadissa Gelalcha, Abebaw Kebede, Hassen Mamo
BACKGROUND: The relatively simple and cheaper light-emitting diode fluorescent microscopy (LED-FM) was recommended by the World Health Organization (WHO) to replace the conventional tuberculosis (TB) microscopy in both high- and low-volume laboratories. More recently the WHO also endorsed one more technique, Xpert MTB/RIF® assay (Xpert), for improved TB diagnosis particularly among human immunodeficiency virus (HIV)-infected cases. However, the relative performance of both of these tools differs from setting to setting in reference to the conventional TB diagnostics...
September 11, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28885940/collaborative-systems-biology-projects-for-the-military-medical-community
#8
Jeffrey J Zalatoris, Julia B Scheerer, Frank J Lebeda
INTRODUCTION: This pilot study was conducted to examine, for the first time, the ongoing systems biology research and development projects within the laboratories and centers of the U.S. Army Medical Research and Materiel Command (USAMRMC). The analysis has provided an understanding of the breadth of systems biology activities, resources, and collaborations across all USAMRMC subordinate laboratories. METHODS: The Systems Biology Collaboration Center at USAMRMC issued a survey regarding systems biology research projects to the eight U...
September 2017: Military Medicine
https://www.readbyqxmd.com/read/28884169/cloud-engineering-principles-and-technology-enablers-for-medical-image-processing-as-a-service
#9
Shunxing Bao, Andrew J Plassard, Bennett A Landman, Aniruddha Gokhale
Traditional in-house, laboratory-based medical imaging studies use hierarchical data structures (e.g., NFS file stores) or databases (e.g., COINS, XNAT) for storage and retrieval. The resulting performance from these approaches is, however, impeded by standard network switches since they can saturate network bandwidth during transfer from storage to processing nodes for even moderate-sized studies. To that end, a cloud-based "medical image processing-as-a-service" offers promise in utilizing the ecosystem of Apache Hadoop, which is a flexible framework providing distributed, scalable, fault tolerant storage and parallel computational modules, and HBase, which is a NoSQL database built atop Hadoop's distributed file system...
April 2017: Proc IEEE Int Conf Cloud Eng
https://www.readbyqxmd.com/read/28877208/surveillance-for-falsified-and-substandard-medicines-in-africa-and-asia-by-local-organizations-using-the-low-cost-gphf-minilab
#10
Albert Petersen, Nadja Held, Lutz Heide
BACKGROUND: Substandard and falsified medical products present a serious threat to public health, especially in low- and middle-income countries. Their identification using pharmacopeial analysis is expensive and requires sophisticated equipment and highly trained personnel. Simple, low-cost technologies are required in addition to full pharmacopeial analysis in order to accomplish widespread routine surveillance for poor-quality medicines in low- and middle-income countries. METHODS: Ten faith-based drug supply organizations in seven countries of Africa and Asia were each equipped with a Minilab of the Global Pharma Health Fund (GPHF, Frankfurt, Germany), suitable for the analysis of about 85 different essential medicines by thin-layer chromatography...
2017: PloS One
https://www.readbyqxmd.com/read/28877177/an-in-vitro-diagnostic-certified-point-of-care-single-nucleotide-test-for-il28b-polymorphisms
#11
Darragh Duffy, Estelle Mottez, Shaun Ainsworth, Tan-Phuc Buivan, Aurelie Baudin, Muriel Vray, Ben Reed, Arnaud Fontanet, Alexandra Rohel, Ventzislava Petrov-Sanchez, Laurent Abel, Ioannis Theodorou, Gino Miele, Stanislas Pol, Matthew L Albert
Numerous genetic polymorphisms have been identified as associated with disease or treatment outcome, but the routine implementation of genotyping into actionable medical care remains limited. Point-of-care (PoC) technologies enable rapid and real-time treatment decisions, with great potential for extending molecular diagnostic approaches to settings with limited medical infrastructure (e.g., CLIA certified diagnostic laboratories). With respect to resource-limited settings, there is a need for simple devices to implement biomarker guided treatment strategies...
2017: PloS One
https://www.readbyqxmd.com/read/28865963/can-shoulder-range-of-movement-be-measured-accurately-using-the-microsoft-kinect-sensor%C3%A2-plus-medical-interactive-recovery-assistant-software
#12
James D Wilson, Jennifer Khan-Perez, Dominic Marley, Susan Buttress, Michael Walton, Baihua Li, Bibhas Roy
BACKGROUND: This study compared the accuracy of measuring shoulder range of movement (ROM) with a simple laptop-sensor combination vs. trained observers (shoulder physiotherapists and shoulder surgeons) using motion capture (MoCap) laboratory equipment as the gold standard. METHODS: The Microsoft Kinect sensor (Microsoft Corp., Redmond, WA, USA) tracks 3-dimensional human motion. Ordinarily used with an Xbox (Microsoft Corp.) video game console, Medical Interactive Recovery Assistant (MIRA) software (MIRA Rehab Ltd...
August 30, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28864983/epigenetic-influences-during-the-periconception-period-and-assisted-reproduction
#13
Akwasi A Amoako, Tamer M Nafee, Bolarinde Ola
The periconception period starts 6 months before conception and lasts until the tenth week of gestation. In this chapter, we will focus on epigenetic modifications to DNA and gene expression within this period and during assisted reproduction. There are two critical times during the periconception window when significant epigenetic 'reprogramming' occur: one during gametogenesis and another during the pre-implantation embryonic stage. Furthermore, assisted conception treatments, laboratory protocols and culture media can affect the embryo development and birth weights in laboratory animals...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28862392/minimizing-exposure-to-radiation-in-invasive-cardiology-using-modern-dose-reduction-technology-evaluation-of-the-real-life-effects
#14
Laurent Faroux, Thierry Blanpain, Pierre Nazeyrollas, Sophie Tassan-Mangina, Benoît Herce, Christophe Tourneux, Damien Metz
OBJECTIVES: We aimed to measure the reduction in the estimated dose of radiation received by patients that can be achieved using dose-reduction technology (ClarityIQ, Philips Healthcare, The Netherlands), among all patients undergoing invasive cardiology procedures. BACKGROUND: Medical procedures remain the primary source of exposure to ionizing radiation in the general population. METHODS: The study population comprised all patients (without exclusion criteria) undergoing invasive coronary procedures over a 1-year study period in a large referral centre equipped with two catheterization laboratories (cathlabs)...
September 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28854719/techniques-used-for-iui-is-it-time-for-a-change
#15
L Lemmens, S Kos, C Beijer, D D M Braat, W L D M Nelen, A M M Wetzels
STUDY QUESTION: Are the guidelines for the technical aspects of IUI (WHO, 2010) still in accordance with the current literature? SUMMARY ANSWER: In general, the laboratory guidelines of the World Health Organization (WHO) are a suitable protocol, although the evidence is not always conclusive and some changes are advisable. WHAT IS KNOWN ALREADY: Lack of standardization of the technical procedures required for IUI might result in inter-laboratory variation in pregnancy rates...
September 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28846019/draft-of-iranian-national-guideline-for-cell-therapy-manufacturing
#16
Hamid Reza Aghayan, Babak Arjmand, Naser Ahmadbeigi, Yousof Gheisari, Mohammad Vasei
Cell therapy, a promising method for treatment of incurable diseases, has been moving fast from basic research laboratories to clinical practice in recent years. Defining clear and strict regulations for manufacturing of cell therapy products in clinical applications is the best way to give assurance to the public sector for safe usage, harmonizing research projects, and placing barriers for unqualified products from entering this market. To achieve this goal, the Iranian Council for Stem cell Science and Technologies sponsored a project in 2013 to develop a national cell therapy guideline for research and clinical trials...
August 2017: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/28842520/improvement-in-immunosuppression-therapy-monitoring-in-organ-transplant-recipients
#17
Stephanie A Thrall, Cory E Fominaya, Jordan M Chiasson, Sharon Castle, David J Taber
PURPOSE: The results of a study to determine whether a technology-enabled pharmacist intervention improved immunosuppression monitoring in organ transplant recipients are presented. METHODS: This was a retrospective, longitudinal cohort study. Eligible patients included veteran solid organ transplant recipients receiving immunosuppression therapy from a Veterans Affairs Medical Center (VAMC) between July 1, 2013, and July 1, 2015. A clinical pharmacist used an electronic surveillance system to determine need for laboratory monitoring and engaged the recipients to obtain regular laboratory monitoring at the VAMC or an outside facility...
September 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28835289/prediction-of-recurrent-clostridium-difficile-infection-using-comprehensive-electronic-medical-records-in-an-integrated-healthcare-delivery-system
#18
Gabriel J Escobar, Jennifer M Baker, Patricia Kipnis, John D Greene, T Christopher Mast, Swati B Gupta, Nicole Cossrow, Vinay Mehta, Vincent Liu, Erik R Dubberke
BACKGROUND Predicting recurrent Clostridium difficile infection (rCDI) remains difficult. METHODS: We employed a retrospective cohort design. Granular electronic medical record (EMR) data had been collected from patients hospitalized at 21 Kaiser Permanente Northern California hospitals. The derivation dataset (2007-2013) included data from 9,386 patients who experienced incident CDI (iCDI) and 1,311 who experienced their first CDI recurrences (rCDI). The validation dataset (2014) included data from 1,865 patients who experienced incident CDI and 144 who experienced rCDI...
August 24, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28832563/participation-in-interdisciplinary-meetings-on-genetic-diagnostics-ngs
#19
Tom Koole, Lotte van Burgsteden, Paulien Harms, Cleo C van Diemen, Irene M van Langen
Diagnostics using next generation sequencing (NGS) requires high-quality interdisciplinary collaboration. In order to gain insight into this crucial collaborative process, we made video recordings of a new multidisciplinary team at work in the clinical genetics department of the University Medical Centre Groningen. Conversation Analysis was used to investigate the ways in which the team members deal with the disciplinary boundaries between them. We found that the team established different 'participation frames' in which to discuss recurring topics...
October 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28831275/beneficiaries-of-conflict-a-qualitative-study-of-people-s-trust-in-the-private-health-care-system-in-mogadishu-somalia
#20
Abdi A Gele, Mohamed Yusuf Ahmed, Prabhjot Kour, Sadiyo Ali Moallim, Abdulwahab Moallim Salad, Bernadette Kumar
BACKGROUND: In 2005, the World Health Conference called for all nations to move toward universal health coverage, which is defined as "access to adequate health care for all at an affordable price". Despite this, an estimated 90% of Somalia's largely impoverished population use private health care. Therefore, considering that the private health care system is the dominant health care system in Mogadishu, Somalia, exploring the accessibility to, as well as people's trust in, the private sector is essential to help contribute an equitable and affordable health care system in the country...
2017: Risk Management and Healthcare Policy
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