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Carpal tunel

Ewa Mizia, Krzysztof Tomaszewski, Pawel Depukat, Wieslawa Klimek-Piotrowska, Artur Pasternak, Izabela Mroz, Tomasz Bonczar
Carpal tunnel syndrome belongs to the most common causative factors of surgical interventions in the wrist region. Anatomy of carpal tunnel and median nerve is a subject of current revision. Authors paid attention to etiology of the syndrome based on review of literature and their own anatomical studies. They remind basic knowledge on the median nerve and indicate that only based on number of dissections a good orthopedic surgeon may acquire experience necessary to perform procedures in a most appropriate way...
2013: Folia Medica Cracoviensia
Jeffrey B Driban, Ann E Barr, Mamta Amin, Michael R Sitler, Mary F Barbe
We used our voluntary rat model of reaching and grasping to study the effect of performing a high-repetition and high-force (HRHF) task for 12 weeks on wrist joints. We also studied the effectiveness of ibuprofen, administered in the last 8 weeks, in attenuating HRHF-induced changes in these joints. With HRHF task performance, ED1+ and COX2+ cells were present in subchondral radius, carpal bones and synovium; IL-1alpha and TNF-alpha increased in distal radius/ulna/carpal bones; chondrocytes stained with Terminal deoxynucleotidyl Transferase- (TDT-) mediated dUTP-biotin nick end-labeling (TUNEL) increased in wrist articular cartilages; superficial structural changes (e...
2011: Journal of Biomedicine & Biotechnology
S Tavella, R Biticchi, R Morello, P Castagnola, V Musante, D Costa, R Cancedda, S Garofalo
Proliferation and apoptosis are two fundamental processes that occur during limb development, and in particular in joint formation. To study the role of hedgehog proteins in limbs, we have misexpressed Sonic Hedgehog specifically in chondrocytes. We found that the appendicular skeleton was severely misshapen while pelvic and shoulder girdles developed normally. In particular, we detected fusion of the elbow/knee joint, no definite carpal/tarsal, metacarpal/metatarsal bones and absence of distinct phalanges, fused in a continuous cartilaginous rod...
September 2006: Matrix Biology: Journal of the International Society for Matrix Biology
No abstract text is available yet for this article.
January 13, 1962: British Medical Journal (1857-1980)
Ranjan Gupta, Oswald Steward
Chronic nerve compression (CNC), as in carpal tunnel syndrome, is a common cause of peripheral nerve dysfunction in humans. Previous studies using animal models have demonstrated progressive demyelination and a slowing of nerve conduction velocity. To characterize the Schwann cell response to CNC, we evaluated total Schwann cell number, apoptosis, and proliferation in an animal model of CNC. Design-based stereologic techniques revealed a striking transient increase in Schwann cell number following CNC. Schwann cell number increased sixfold relative to the normal nerve at the site of compression at 1 month and then slowly declined toward control levels...
June 23, 2003: Journal of Comparative Neurology
E Fertl, C Wöber, J Zeitlhofer
OBJECTIVES: 1) To examine the diagnostic value of the newly proposed manual carpal compression test (mCCT). 2) To evaluate the test efficacy of a serial use of mCCT and Phalen's test (PT) in the clinical diagnosis of carpal tunnel syndrome (CTS) in comparison with standard nerve conduction studies. MATERIALS AND METHODS: Prospective, controlled study of 47 patients with 63 symptomatic CTS hands according to clinical as well as electrophysiological criteria. In the control group, 39 hands of 20 healthy volunteers were examined...
November 1998: Acta Neurologica Scandinavica
E L Steinberg, E Luger, C Taitz, B Arensburg
Forty-six hands of 23 cadavers (15 female and 8 male) were dissected to observe the patterns of distribution of the median nerve. The findings showed that in 33 hands the median nerve had a normal distribution of its branches. Also identified was the commonly recognized transligamentous variant, where the recurrent branch pierces the carpal ligament 2 to 4 mm proximal to the distal end of the carpal tunel. This latter variant occurred in 13 hands. The current study focused on the presence of an additional variant, not previously identified, that occurred in 10 hands...
July 1998: Clinical Orthopaedics and related Research
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