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Vulvar dermatology

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https://www.readbyqxmd.com/read/27415635/folliculocentric-lichen-sclerosus-et-atrophicus-in-a-10-year-old-girl
#1
Constantin El Habr, Kathleen Mannava, Sara Koch, Rechelle Tull, Belen Goiburu-Chenu, Lindsay Strowd, Omar Sangueza
Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory scarring disease with a predilection for the anogenital area; however, 15%-20% of LSA cases are extragenital. The folliculocentric variant is rarely reported and less well understood. The authors report a rare case of extragenital, folliculocentric LSA in a 10-year-old girl. The patient presented to the dermatology clinic for evaluation of an asymptomatic eruption of the arms and legs, with no vaginal or vulvar involvement. Physical examination revealed the presence of numerous 2-4 mm, mostly perifollicular, hypopigmented, slightly atrophic papules and plaques...
July 12, 2016: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/27206219/risk-factors-for-de-novo-malignancies-in-women-after-kidney-transplantation-a-multicenter-transversal-study
#2
Samir Helmy, Julian Marschalek, Yvonne Bader, Marianne Koch, Alice Schmidt, Marina Kanzler, Georg Gyoeri, Stephan Polterauer, Alexander Reinthaller, Christoph Grimm
OBJECTIVE: Transplantation results in a 5-time elevated risk for a variety of malignancies (Kaposi sarcoma, skin, liver, lung, gastrointestinal cancer). A patient's risk for malignancies could be of particular interest for the follow-up programs of patients and risk adaption after kidney transplantation. The aim of this study was to identify independent risk factors for de novo malignancies in women after renal transplantation. METHODS AND MATERIALS: This is a multicenter transversal study, conducted at the Medical University of Vienna and Hospital Rudolfstiftung, Vienna, Austria...
June 2016: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/26692611/physician-administered-clinical-score-of-vulvar-lichen-sclerosus-a-study-of-36-cases
#3
Smriti Naswa, Yogesh S Marfatia
INTRODUCTION: Vulvar lichen sclerosus (VLS) often remains undetected for years due to lack of awareness, as well as private nature of the disease. Advanced disease severely affects the quality of life and is associated with increased risk of vulvar squamous cell carcinoma (SCC). The aim of this study was to assess the usefulness of a physician-administered clinical scoring system for the clinical diagnosis and evaluation of VLS. To the best of our knowledge, this is the first study using the clinical score developed by Günthert et al on the VLS patients...
July 2015: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/26677274/genital-perigenital-inflammatory-linear-verrucous-epidermal-nevus-a-case-series
#4
Debabrata Bandyopadhyay, Abanti Saha
BACKGROUND: Inflammatory linear verrucous epidermal nevus (ILVEN) is a distinct variety of keratinocytic epidermal naevus. In contrast to non-inflammatory epidermal naevi, ILVEN are far less common, usually erythematous and intractably pruritic. ILVEN usually appears at birth or early childhood and has a linear distribution following the Blaschko lines. Genital/perigenital involvement is relatively rare. OBJECTIVES: To describe the clinical features of 9 children with ILVEN localized to the genital and perigenital areas...
November 2015: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/26348378/surgical-management-of-vulvovaginal-agglutination-due-to-lichen-planus
#5
Pamela S Fairchild, Hope K Haefner
Lichen planus is a rare dermatological disorder that is often associated with painful and disfiguring vulvovaginal effects. At the University of Michigan Center for Vulvar Diseases, we see many women with vulvovaginal lichen planus each year, with marked scarring and vulvovaginal agglutination that precludes vaginal intercourse and causes difficulty with urination. Through our experience, we developed a protocol for the operative management and postoperative care for severe vulvovaginal agglutination. Our objective is to share this protocol with a wider audience so that providers who see patients with these devastating effects of lichen planus can benefit from our experience to better serve this patient population...
February 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/26259393/unilateral-angiokeratoma-of-vulva-a-rare-clinic-entity
#6
Aytekin Tokmak, Demet Kokanali, Nagihan Ozcan Cengaver, Gülçin Yildirim, Ali Irfan Güzel, Nafiye Yilmaz
The aim of this study is to present a very rare dermatologic condition of the vulva. Angiokeratoma is a benign dilation of ectatic thin-walled blood vessels and congested capillaries in the superficial dermal layer of skin. It occurs predominantly in men and extremely rare in women. Angiokeratoma presents as single or multiple papular lesions on the vulva with smooth or verrucous surface. These lesions are easily confused with infectious disease, inflammatory lesions, and epithelial tumors. In this report, we presented a 42 year old unmarried woman who was admitted to our clinic with complaints of two papuler lesions of the right labium majus with vaginal discharge, vulvar pruritis, and vulvar edema...
2015: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/26193225/perineal-reconstruction-with-biologic-graft-vulvoplasty-for-verrucous-carcinoma-treated-by-repeated-vulvar-excisions-a-case-report
#7
Elvira Brătilă, Cornel Petre Brătilă, Diana Elena Comandaşu, Vasilica Bauşic, Doina Mihaela Pop, Vlad Denis Constantin, Monica Mihaela Cîrstoiu, Ruxandra Stănculescu
Vulvar neoplasia represents 5% of malignancies in female genital tract and 0.6% of all cancers in women. Although it is known to be a rare type of cancer, which occurs especially in elderly women, its incidence is increasing in young females because of its association with the human papillomavirus (HPV). In this paper, we report the case of a 46-year-old woman, gravidity 4, parity 3, with a medical history of multiple vulvar excisions for recurrent ulcerative vulvar lesions during a period of 11 years. The first lesion appeared in 2003, it was excised and the histopathological result showed squamous cell carcinoma with undifferentiated areas and chronic ulcerative inflammation...
2015: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/26125964/psychosexual-aspects-of-vulvar-disease
#8
REVIEW
Talli Y Rosenbaum, Ellen Barnard, Myrtle Wilhite
Physically, the vulva is an anatomic location of convergence, which includes vascular, neural, hormonal, reproductive, dermatologic, and musculoskeletal systems. Psychosocially, the vulva represents privacy, femininity, sexuality, and intimacy. Because of this intertwined relationship, vulvar disease and dysfunction can significantly impact a woman's physical health as well as her relationships. This article elucidates the impact of vulvar disease on the individual psyche, sexual functioning, and intimate relationships...
September 2015: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/26125955/inflammatory-vulvar-dermatoses
#9
REVIEW
Angela Guerrero, Aruna Venkatesan
Inflammatory vulvar dermatoses affect many women, but are likely underdiagnosed due to embarrassment and reluctance to visit a health care provider. Although itch and pain are common presenting symptoms, the physical examination can help distinguish between different disease entities. Because many women's health providers have minimal training in the categorization and management of dermatologic disease, definitive diagnosis and management can be difficult. Herein, strategies for diagnosing vulvar lichen sclerosus, lichen planus, contact dermatitis, lichen simplex chronicus, and psoriasis are discussed along with basic management of these diseases, which commonly involves decreasing inflammation through behavioral change, gentle skin care, topical corticosteroids, and systemic therapies...
September 2015: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/26003033/-vulvar-oedema-revealing-systemic-mastocytosis
#10
E Deveza, F Locatelli, M Girardin, S Valmary-Degano, E Daguindau, F Aubin, P Humbert, F Pelletier
BACKGROUND: Systemic mastocytosis is characterised by abnormal proliferation of mast cells in various organs. We report an original case of systemic mastocytosis revealed by vulvar oedema. PATIENTS AND METHODS: A 24-year-old patient was examined in the dermatology department for vulvar oedema appearing during sexual intercourse. She presented vasomotor dysfunction of the lower limbs, urticaria on the trunk on exertion, diarrhoea and bone pains. Laboratory tests showed serum tryptase of 29...
November 2015: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/25757813/resolution-of-chronic-vulvar-pruritus-with-replacement-of-a-neuromodulation-device
#11
REVIEW
Audra Jolyn Hill, Marie Fidela R Paraiso
Vulvar pruritus is typically associated with fungal, bacterial, and/or dermatological conditions that routinely resolve with the use of topical medications. Pruritus rarely becomes chronic in nature without a definable pathological diagnosis. However, when this occurs, management is difficult and has limited treatment options. Few cases have reported resolution of vulvar pain or discomfort with sacral neuromodulation implantation. We report a case in which a patient experienced chronic vulvar pruritus that was refractory to medical treatments and did not have a pathological diagnosis...
July 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/25540566/dermatosis-associated-with-menopause
#12
REVIEW
Pragya A Nair
Menopause is defined as permanent irreversible cessation of menses brought by decline in ovarian follicular activity. Hormonal alteration results in various physical, psychological, and sexual changes in menopausal women. Associated dermatological problems can be classified as physiological changes, age-related changes, changes due to estrogen deficiency and due to hormone replacement therapy. Dermatosis seen due to estrogen deficiency includes Atrophic Vulvovaginitis, Vulvar Lichen Sclerosus, Dyaesthetic Vulvodynia, Hirsutism, Alopecia, Menopausal Flushing, Keratoderma Climactericum, Vulvovaginal Candidiasis...
October 2014: Journal of Mid-life Health
https://www.readbyqxmd.com/read/25475624/-vulvar-diseases
#13
M Peckruhn, P Elsner
Vulvar diseases might cause problems in the differential diagnosis, because the clinical presentation of inflammatory, infectious and neoplastic disorders may be quite similar. Itching and pain as well as dysuria and dyspareunia are the most common symptoms of vulvar diseases. Inflammatory dermatoses like atopic and contact dermatitis, lichen planus, lichen sclerosus and atrophic vulvitis account for the majority of cases in specialized clinics. Furthermore, neoplastic conditions such as vulvar carcinoma, vulvar intraepithelial neoplasia (VIN) and vulvar Paget's disease have to be considered...
January 2015: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/25143670/basal-cell-carcinoma-mimicking-lesions-in-korean-clinical-settings
#14
Hoon-Soo Kim, Tae-Wook Kim, Je-Ho Mun, Margaret Song, Hyun-Chang Ko, Byung-Soo Kim, Moon-Bum Kim
BACKGROUND: Basal cell carcinoma (BCC) is the most common form of skin cancer and possesses various clinical features including translucency, ulceration, pigmentation, telangiectasia, and rolled borders. Accordingly, many cutaneous lesions can mimic BCCs and differential diagnosis is difficult. OBJECTIVE: To clarify the differences in clinical characteristics between BCCs and BCC-mimicking lesions (BMLs), and to determine which clinical characteristics are helpful for an accurate clinical diagnosis of BCC...
August 2014: Annals of Dermatology
https://www.readbyqxmd.com/read/25134451/paediatric-vulvar-disease
#15
REVIEW
Rosalind C Simpson, Ruth Murphy
Paediatric vulvar skin conditions are relatively common but often cause diagnostic difficulties for clinicians, which can lead to anxiety within the children's families. Vulvar skin conditions can be caused by various underlying aetiologies. Most are general dermatologic conditions that occur in the vulvar area, such as eczema, psoriasis, skin lesions or infections. However, other conditions such as lichen sclerosus and napkin dermatitis ('nappy rash') only affect the genital region. Every affected child needs a sensitive evaluation of the complaint including an assessment of the impact of the condition on the patient and her family...
October 2014: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/25106700/vulvar-intraepithelial-neoplasia
#16
REVIEW
Mario Preti, James Scurry, Claudia E Marchitelli, Leonardo Micheletti
Vulvar intraepithelial neoplasia (VIN) is a high-grade intraepithelial squamous lesion and precursor of invasive squamous cell carcinoma (SCC). The 2004 International Society for the Study of Vulvovaginal Disease (ISSVD) classification distinguished two types of VIN: usual type (human papillomavirus (HPV)-related) and differentiated type (not HPV-related). The incidence of usual-type VIN is higher in younger women, while differentiated-type VIN is more common in older patients with chronic dermatologic conditions...
October 2014: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/25010585/trends-in-pharmacy-compounding-for-women-s-health-in-north-carolina-focus-on-vulvodynia
#17
Susan H Corbett, Gary Cuddeback, Jasmine Lewis, Swasan As-Sanie, Denniz Zolnoun
OBJECTIVES: To identify trends in compounding pharmacies with a focus on women's health and, more specifically, the types and combinations of medications used in the treatment of vulvodynia. METHODS: This survey study was conducted with 653 nonchain pharmacies that compound medications. Each pharmacy was asked to complete a 19-item online survey assessing general practice and common compounding indications, focusing on women's health. RESULTS: Of the 653 pharmacies contacted, 200 (31%) responded to our survey...
July 2014: Southern Medical Journal
https://www.readbyqxmd.com/read/24955917/-vulvar-lichen-sclerosus-in-a-girl-with-turner-syndrome
#18
Dolores Ocampo, Verónica González
Dermatological complications in Turner syndrome are infrequent but occasionally cause significant morbidity. Lichen sclerosus (LS) is a chronic inflammatory mucocutaneous affection characterized by pruritus in the anogenital area. It is yet not clear its pathophysiology but it's linked with genetic factors and autoimmunity. This is a case report of a girl with Turner syndrome with growth hormone treatment that started with vulvar pruritus and was diagnosed as lichen sclerosus.
August 2014: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/24711996/pruritus-in-female-patients
#19
REVIEW
Julien Lambert
Pruritus is a frequent symptom in many dermatological diseases. In this review we want to focus on not only itch problems specific to women, namely, pruritic vulvodermatoses, but also the specific pruritic dermatoses of pregnancy. The specific characteristics of the vulva and the hormonal changes during the different age periods make these dermatoses very particular. It seems that vulvar diseases are still underdiagnosed and undertreated. Pruritic vulvar diseases have a huge impact on quality of life. The most common pruritic diseases will be discussed, such as atopic and contact dermatitis, psoriasis, lichen sclerosis, lichen planus, and infectious vulvaginitis...
2014: BioMed Research International
https://www.readbyqxmd.com/read/24696010/uv-a1-phototherapy-vs-clobetasol-propionate-0-05-in-the-treatment-of-vulvar-lichen-sclerosus-a-randomized-clinical-trial
#20
RANDOMIZED CONTROLLED TRIAL
Sarah Terras, Thilo Gambichler, Rose K C Moritz, Markus Stücker, Alexander Kreuter
IMPORTANCE: Topical corticosteroids are the current first-line therapy for vulvar lichen sclerosus (VLS). UV-A1 phototherapy may be a promising alternative treatment option, but controlled studies are lacking. OBJECTIVE: To compare the efficacy of high-potent topical corticosteroids with UV-A1 phototherapy in the treatment of VLS. DESIGN, SETTING, AND PARTICIPANTS: A 2-arm randomized clinical trial was conducted at a university hospital dermatology department according to the intention-to-treat principle with last observation carried forward...
June 2014: JAMA Dermatology
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