keyword
MENU ▼
Read by QxMD icon Read
search

Creatinine AND GFR

keyword
https://www.readbyqxmd.com/read/28329858/cystatin-c-and-the-risk-of-frailty-and-mortality-in-older-men
#1
Allyson Hart, Terri L Blackwell, Misti L Paudel, Brent C Taylor, Eric S Orwoll, Peggy M Cawthon, Kristine E Ensrud
Background: This study examines the association between cystatin C (cysC) levels and risks of progression of frailty status or death in older men. Methods: Prospective study of 2,613 men without overt frailty aged 67 years and older enrolled in the MrOS ancillary sleep study. Baseline measurements included serum cysC, serum creatinine, and frailty status. Repeat frailty status, performed an average of 3.4 years later, was assessed as an ordinal outcome of robust, intermediate stage (prefrail), frail or dead...
November 9, 2016: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28321323/total-kidney-volume-as-a-biomarker-of-disease-progression-in-autosomal-dominant-polycystic-kidney-disease
#2
REVIEW
Navdeep Tangri, Ingrid Hougen, Ahsan Alam, Ronald Perrone, Phil McFarlane, York Pei
PURPOSE OF REVIEW: Autosomal dominant polycystic kidney disease (ADPKD) is an inherited disorder characterized by the formation of kidney cysts and kidney enlargement, which progresses to kidney failure by the fifth to seventh decade of life in a majority of patients. Disease progression is evaluated primarily through serum creatinine and estimated glomerular filtration rate (eGFR) measurements; however, it is known that serum creatinine and eGFR values typically do not change until the fourth or fifth decade of life...
2017: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/28317454/comparison-of-methods-for-estimating-glomerular-filtration-rate-in-head-and-neck-cancer-patients-treated-with-cisplatin
#3
Lotte Lindberg, Kasper Brødbæk, Erik G Hägerström, Jens Bentzen, Bent Kristensen, Bo Zerahn
Cisplatin is a chemotherapeutic agent widely used in the treatment of various solid tumors. Cisplatin induces nephrotoxicity and may lead to long-term reduction of kidney function. Consequently, determination of glomerular filtration rate (GFR) is used to monitor potential kidney damage. This study aimed to compare two commonly used algorithms for estimating GFR (eGFR) from plasma creatinine (PCr) with (51)Cr-EDTA clearance (CrCl) as a reference method. This was a retrospective single center study of 94 head and neck cancer patients treated with cisplatin...
March 20, 2017: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/28315878/dexamethasone-modifies-cystatin-c-based-diagnosis-of-acute-kidney-injury-during-cisplatin-based-chemotherapy
#4
Timothy J Pianta, John W Pickering, Lena Succar, Melvin Chin, Trent Davidson, Nicholas A Buckley, Fahim Mohamed, Zoltan H Endre
BACKGROUND/AIMS: Plasma cystatin C (pCysC) may be superior to serum creatinine (sCr) as a surrogate of GFR. However, the performance of pCysC for diagnosing acute kidney injury (AKI) after cisplatin-based chemotherapy is potentially affected by accompanying corticosteroid anti-emetic therapy and hydration. METHODS: In a prospective observational study pCysC, sCr, urinary kidney injury molecule-1 (KIM-1), and urinary clusterin were measured over 2 weeks in 27 patients given first-cycle chemotherapy...
March 17, 2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/28306749/cigarette-smoking-and-cardio-renal-events-in-patients-with-atherosclerotic-renal-artery-stenosis
#5
Christopher A Drummond, Pamela S Brewster, Wencan He, Kaili Ren, Yanmei Xie, Katherine R Tuttle, Steven T Haller, Kenneth Jamerson, Lance D Dworkin, Donald E Cutlip, Timothy P Murphy, Ralph B D'Agostino, William L Henrich, Jiang Tian, Joseph I Shapiro, Christopher J Cooper
Cigarette smoking causes cardiovascular disease and is associated with poor kidney function in individuals with diabetes mellitus and primary kidney diseases. However, the association of smoking on patients with atherosclerotic renal artery stenosis has not been studied. The current study utilized data from the Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL, NCT00081731) clinical trial to evaluate the effects of smoking on the risk of cardio-renal events and kidney function in this population...
2017: PloS One
https://www.readbyqxmd.com/read/28306525/efficient-reporting-of-the-estimated-glomerular-filtration-rate-without-height-in-pediatric-patients-with-cancer
#6
Tae-Dong Jeong, Eun-Jung Cho, Woochang Lee, Sail Chun, Ki-Sook Hong, Won-Ki Min
BACKGROUND: The updated bedside Schwartz equation requires constant, serum creatinine concentration and height measurements to calculate the estimated glomerular filtration rate (eGFR) in pediatric patients. Unlike the serum creatinine levels, obtaining height information from the laboratory information system (LIS) is not always possible in a clinical laboratory. Recently, the height-independent eGFR equation, the full age spectrum (FAS) equation, has been introduced. We evaluated the performance of height-independent eGFR equation in Korean children with cancer...
March 15, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28296256/estimation-of-glomerular-filtration-rate-in-elderly-chronic-kidney-disease-patients-comparison-of-three-novel-sophisticated-equations-and-simple-cystatin-c-equation
#7
Sebastjan Bevc, Nina Hojs, Radovan Hojs, Robert Ekart, Maksimiljan Gorenjak, Ludvik Puklavec
Estimating glomerular filtration rate (GFR) in elderly patients is a problem, since they are poorly represented in studies developing GFR equations. Serum cystatin C is a better indicator of GFR than serum creatinine in elderly patients. Therefore the aim of our study was to compare frequently used serum cystatin C based GFR equations with a gold standard ((51) CrEDTA clearance) in elderly chronic kidney disease (CKD) patients. 106 adult Caucasian patients, older than 65 years (58 women, 48 men; mean age 72...
March 10, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28294855/-relationship-between-blood-serum-galectin-and-renal-dysfunction-in-st-elevation-myocardial-infarction
#8
V N Karetnikova, A V Osokina, M V Evseeva, O V Gruzdeva, M V Zykov, V V Kalaeva, V V Kashtalap, K S Shafranskaya, O N Khryachkova, O L Barbarash
AIM: to assess value for inhospital and 1 year prognosis of unfavorable course of ST-elevation myocardial infarction (STEMI) of blood serum galectin and markers of renal dysfunction (RD). MATERIAL AND METHODS: Standard laboratory and instrumental examination, calculation of glomerular filtration rate using MDRD formula and by cystatin C level, determination of galectin in blood serum were carried out in 128 patients with STEMI. According to GFR by cystatin C level on day 12 of STEMI patients were divided into 2 groups - with normal renal function (GFR more or equal 60 ml/min/1...
April 2016: Kardiologiia
https://www.readbyqxmd.com/read/28292877/the-effects-of-dual-ppar%C3%AE-%C3%AE-agonism-compared-with-ace-inhibition-in-the-btbrob-ob-mouse-model-of-diabetes-and-diabetic-nephropathy
#9
Anette Ericsson, Pernilla Tonelius, Mark Lal, Alan Sabirsh, Gerhard Böttcher, Lena William-Olsson, Maria Strömstedt, Camilla Johansson, Gina Hyberg, Sofia Tapani, Ann-Cathrine Jönsson-Rylander, Robert Unwin
The leptin-deficient BTBRob/ob mouse develops progressive albuminuria and morphological lesions similar to human diabetic nephropathy (DN), although whether glomerular hyperfiltration, a recognized feature of early DN that may contribute to renal injury, also occurs in this model is not known. Leptin replacement has been shown to reverse the signs of renal injury in this model, but in contrast, the expected renoprotection by angiotensin-converting enzyme (ACE) inhibition in BTBRob/ob mice seems to be limited...
March 2017: Physiological Reports
https://www.readbyqxmd.com/read/28292271/two-elderly-patients-with-normal-creatinine-and-elevated-cystatin-c-a-case-report
#10
Amina Loesment-Wendelmuth, Elke Schaeffner, Natalie Ebert
BACKGROUND: Serum creatinine concentration (Scr) and creatinine based GFR estimating equations (eGFRcr) are commonly used as an estimate of GFR. However, serum creatinine concentration is also influenced by non-GFR determinants. This case report presents two elderly patients with normal Scr but elevated serum cystatin C concentration (Scys) where the exclusive assessment of Scr would have lead to an overestimation of GFR and would have misclassified the patients as having a normal kidney function...
March 14, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28290891/-the-role-of-urinary-lipocalin-in-prognostication-of-hospital-complications-in-patients-with-ischemic-heart-disease-after-coronary-artery-bypass-grafting
#11
K S Shafranskaya, O K Kuzmina, D A Sumin, K Ye Krivoshapova, Ye G Uchasova, S V Ivanov, M V Zykov, V V Kashtalap, O L Barbarash
PURPOSE: To assess significance of urinary neutrophil gelatinase-associated lipocalin (NGAL) for predicting hospital complications in subjects with ischemic heart disease (IHD) after coronary artery bypass grafting (CABG). MATERIALS AND METHODS: The study included 720 subjects who underwent CABG between 03/2011 and 04/2012. Blood serum creatinine level, glomerular filtration rate (GFR) (MDRD formula) and NGAL concentration were measured before and on day 7 after CABG...
October 2016: Kardiologiia
https://www.readbyqxmd.com/read/28290865/-chronic-reno-cardial-continuum-in-glomerulonephritis
#12
I T Murkamilov, R R Kaliev, A Sh Sarybaev, J Sh Imanakunova, B F Imanov, A A Ibragimov, N T Davidova
OBJECTIVES: To elucidate main risk factors contributing to development of cardiovascular pathology at the predialysis stage of chronic glomerulonephritis. MATERIALS AND METHODS: We examined 173 patients (90 men, 83 women, age 15-70, mean age 36.8+/-12.9 years) at predialysis stage of chronic glomerulonephritis. Cardiovascular pathology (coronary heart disease, disturbances of cardiac rhythm, left ventricular hypertrophy, chronic heart failure) was found in 88 patients...
September 2016: Kardiologiia
https://www.readbyqxmd.com/read/28289595/case-report-of-a-novel-mutation-of-the-eya1-gene-in-a-patient-with-branchio-oto-renal-syndrome
#13
L Spahiu, B Merovci, V Ismaili Jaha, A Batalli Këpuska, H Jashari
Branchio-oto-renal (BOR) syndrome is an autosomal dominant disorder characterized by the coexistence of branchial cysts or fistulae, external ear malformation with pre-auricular pits or tags, hearing impairment and renal malformations. However, the presence of the main features varies in affected families. Here, we present a 16-year-old boy admitted to the Department of Nephrology at the Pediatric Clinic, University Clinical Center of Kosovo, Pristina, Republic of Kosovo because of severe renal insufficiency diagnosed 6 years ago, which progressed to end-stage renal failure...
December 1, 2016: Balkan Journal of Medical Genetics: BJMG
https://www.readbyqxmd.com/read/28288249/association-of-intensive-blood-pressure-control-and-kidney-disease-progression-in-nondiabetic-patients-with-chronic-kidney-disease-a-systematic-review-and-meta-analysis
#14
Wan-Chuan Tsai, Hon-Yen Wu, Yu-Sen Peng, Ju-Yeh Yang, Hung-Yuan Chen, Yen-Ling Chiu, Shih-Ping Hsu, Mei-Ju Ko, Mei-Fen Pai, Yu-Kang Tu, Kuan-Yu Hung, Kuo-Liong Chien
Importance: The optimal blood pressure (BP) target remains debated in nondiabetic patients with chronic kidney disease (CKD). Objective: To compare intensive BP control (<130/80 mm Hg) with standard BP control (<140/90 mm Hg) on major renal outcomes in patients with CKD without diabetes. Data Sources: Searches of PubMed, MEDLINE, Embase, and Cochrane Library for publications up to March 24, 2016. Study Selection: Randomized clinical trials that compared an intensive vs a standard BP target in nondiabetic adults with CKD, reporting changes in glomerular filtration rate (GFR), doubling of serum creatinine level, 50% reduction in GFR, end-stage renal disease (ESRD), or all-cause mortality...
March 13, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28276725/accuracy-diagrams-a-novel-way-to-illustrate-uncertainty-of-estimated-gfr
#15
Jonas Björk, Anders Grubb, Gunnar Sterner, Sten-Erik Bäck, Ulf Nyman
Most studies that validate GFR equations present accuracy results stratified by measured GFR (mGFR; diagnostic correctness) or by estimated GFR (eGFR; diagnostic predictiveness) only, without a clear distinction in interpretation. The accuracy of a GFR equation is normally reported in percent (e.g. P30), but is often misinterpreted when stratified by eGFR. The aim of the study was to develop new accuracy measures and diagrams that allow straightforward interpretations and illustrations of the uncertainty in eGFR in clinical practice...
May 2017: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/28263109/glomerular-filtration-rate-determination-by-computed-tomography-in-two-pet-rabbits-with-renal-disease
#16
Graham Zoller, Isabelle Langlois, Kate Alexander
CASE DESCRIPTION A 3-year-old and a 7-year-old spayed female rabbit (Oryctolagus cuniculus) were evaluated because of digestive stasis associated with renal asymmetry. CLINICAL FINDINGS Neoplasia of the right kidney was diagnosed via cytologic analysis in the 3-year-old rabbit. Ureterolithiasis of the left kidney was diagnosed via abdominal ultrasonography in the 7-year-old rabbit. To evaluate whether unilateral nephrectomy was indicated, evaluation of glomerular filtration rate by dynamic CT (CT-GFR) was performed on both rabbits...
March 15, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28262263/renal-function-is-similar-in-solitary-kidneys-from-patients-with-and-without-diabetes
#17
Cristina Gluhovschi, Gheorghe Gluhovschi, Florica Gadalean, Silvia Velciov, Ligia Petrica, Bogdan Timar, Adriana Kaycsa, Romulus Timar
OBJECTIVES: Due to the shortage of living kidney donors and the current diabetes mellitus (DM) pandemic, studying the association of solitary kidney (SK) with DM is of paramount importance. Our aim was to assess the significance of the association between SK and DM. MATERIALS AND METHODS: Eighty-four patients with SK and DM (group A), with a mean age of 62.46±12.72 years, of whom 36 were males and 48 were females, were enrolled in the study. The control group (group B) comprised 84 SK patients without DM of similar age and duration of existence of a SK...
March 2, 2017: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/28260391/endothelial-glycocalyx-damage-and-renal-dysfunction-in-hiv-patients-receiving-combined-antiretroviral-therapy
#18
Gdayllon Cavalcante Meneses, Malena Gadelha Cavalcante, Geraldo Da Silva Junior, Alice Maria Costa Martins, Roberto da Justa Pires Neto, Alexandre Liborio, Elizabeth Daher
BACKGROUND: Widespread use of combined antiretroviral therapy (cART) increase HIV patients' life expectancy, however favored the development of kidney and cardiovascular diseases. The aim of this study was to investigate endothelial glycocalyx damage and its association with renal function in HIV patients receiving cART. METHODS: This is a cross-sectional study with HIV-infected patients with no renal and cardiovascular disease, recruited in public health centers in Brazil...
March 6, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28245797/blood-pressure-and-age-related-gfr-decline-in-the-general-population
#19
Bjørn O Eriksen, Vidar T N Stefansson, Trond G Jenssen, Ulla D Mathisen, Jørgen Schei, Marit D Solbu, Tom Wilsgaard, Toralf Melsom
BACKGROUND: Hypertension is one of the most important causes of end-stage renal disease, but it is unclear whether elevated blood pressure (BP) also accelerates the gradual decline in the glomerular filtration rate (GFR) seen in the general population with increasing age. The reason may be that most studies have considered only baseline BP and not the effects of changes in BP, antihypertensive treatment and other determinants of GFR during follow-up. Additionally, the use of GFR estimated from creatinine or cystatin C instead of measurements of GFR may have biased the results because of influence from non-GFR related confounders...
February 28, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28245441/childhood-estimates-of-glomerular-filtration-rate-based-on-creatinine-and-cystatin-c-importance-of-body-composition
#20
Kozeta Miliku, Hanneke Bakker, Eiske M Dorresteijn, Karlien Cransberg, Oscar H Franco, Janine F Felix, Vincent W V Jaddoe
BACKGROUND: Creatinine and cystatin C concentrations are commonly used to estimate glomerular filtration rate (eGFR) in clinical practice and epidemiological studies. To estimate the influence of different body composition measures on eGFR from creatinine and cystatin C blood concentrations, we compared the associations of different anthropometric and body composition measures with eGFR derived from creatinine (eGFRcreat) and cystatin C (eGFRcystC) blood concentrations. METHODS: In a population-based cohort study among 4,305 children aged 6...
March 1, 2017: American Journal of Nephrology
keyword
keyword
92626
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"