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Pre operative cognitive assessment

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https://www.readbyqxmd.com/read/27909405/classifying-cognitive-profiles-using-machine-learning-with-privileged-information-in-mild-cognitive-impairment
#1
Hanin H Alahmadi, Yuan Shen, Shereen Fouad, Caroline Di B Luft, Peter Bentham, Zoe Kourtzi, Peter Tino
Early diagnosis of dementia is critical for assessing disease progression and potential treatment. State-or-the-art machine learning techniques have been increasingly employed to take on this diagnostic task. In this study, we employed Generalized Matrix Learning Vector Quantization (GMLVQ) classifiers to discriminate patients with Mild Cognitive Impairment (MCI) from healthy controls based on their cognitive skills. Further, we adopted a "Learning with privileged information" approach to combine cognitive and fMRI data for the classification task...
2016: Frontiers in Computational Neuroscience
https://www.readbyqxmd.com/read/27903334/applying-an-evidence-based-assessment-model-to-identify-students-at-risk-for-perceived-academic-problems-following-concussion
#2
Danielle M Ransom, Alison R Burns, Eric A Youngstrom, Christopher G Vaughan, Maegan D Sady, Gerard A Gioia
OBJECTIVES: The aim of this study was to demonstrate the utility of an evidence-based assessment (EBA) model to establish a multimodal set of tools for identifying students at risk for perceived post-injury academic problems. METHODS: Participants included 142 students diagnosed with concussion (age: M=14.95; SD=1.80; 59% male), evaluated within 4 weeks of injury (median=16 days). Demographics, pre-injury history, self- and parent-report measures assessing symptom severity and executive functions, and cognitive test performance were examined as predictors of self-reported post-injury academic problems...
November 2016: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/27825661/development-and-validation-of-a-mental-practice-tool-for-total-abdominal-hysterectomy
#3
Said S Saab, Jamie Bastek, Sandra Dayaratna, Ellyn Hutton, Catherine R Salva
OBJECTIVE: Total abdominal hysterectomy (TAH) is a common operation performed by obstetrician-gynecologists. Training opportunities for this procedure are declining. Mental practice (MP), the use of mental imagery to rehearse a task symbolically before performance, has been used successfully in sports and music to enhance skill. This strategy demonstrates benefit in existing surgical education literature. We aimed to develop and validate a MP tool (MPT) for resident training in TAH. DESIGN: A prospective survey study was performed in a large, urban, academic medical center in Philadelphia, Pennsylvania, USA...
November 4, 2016: Journal of Surgical Education
https://www.readbyqxmd.com/read/27814622/interventions-in-parkinson-s-disease-role-of-executive-function
#4
Abhimanyu Mahajan, Jennifer A Deal, Michelle Carlson
The cortico-striatal network plays a major role in executive functions (EF), and is believed to play a role in the pathophysiology of Parkinson's disease (PD). However, the tools to assess EF are limited. This review assesses the impact of all PD interventions, namely, pharmacotherapy, physical exercise and Deep Brain Stimulation (DBS) surgery on EF. The effect of PD pharmacotherapy varies with the drug class, neuropsychological test used and the affected dopamine receptor family. There appears to be a benefit of aerobic exercise on EF, including judgment and attention...
January 1, 2017: Frontiers in Bioscience (Landmark Edition)
https://www.readbyqxmd.com/read/27812138/assessing-self-awareness-through-gaze-agency
#5
Regina Gregori Grgič, Sofia Allegra Crespi, Claudio de'Sperati
We define gaze agency as the awareness of the causal effect of one's own eye movements in gaze-contingent environments, which might soon become a widespread reality with the diffusion of gaze-operated devices. Here we propose a method for measuring gaze agency based on self-monitoring propensity and sensitivity. In one task, naïf observers watched bouncing balls on a computer monitor with the goal of discovering the cause of concurrently presented beeps, which were generated in real-time by their saccades or by other events (Discovery Task)...
2016: PloS One
https://www.readbyqxmd.com/read/27761038/a-comparison-of-the-effect-of-two-doses-of-oral-melatonin-with-oral-midazolam-and-placebo-on-pre-operative-anxiety-cognition-and-psychomotor-function-in-children-a-randomised-double-blind-study
#6
Madhuri S Kurdi, Sindhu Priya Muthukalai
BACKGROUND AND AIMS: Melatonin (MT), a naturally occurring pituitary hormone has a sleep promoting effect. There are very few studies on pre-operative oral MT (0.2-0.5 mg/kg) in children. We planned a study to assess the efficacy of oral MT in two doses and compare it with oral midazolam and placebo for pre-operative anxiolysis, sedation, maintenance of cognition and psychomotor skills, parental separation behaviour and venepuncture compliance. METHODS: This prospective double-blind randomised study was conducted after ethical committee approval on 100 children aged 5-15 years, American Society of Anaesthesiologists physical status I and II undergoing elective surgery at our hospital from January 1, 2014, to December 31, 2014...
October 2016: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/27693618/abbreviated-environmental-enrichment-confers-neurobehavioral-cognitive-and-histological-benefits-in-brain-injured-female-rats
#7
Hannah L Radabaugh, Lauren J Carlson, Darik A O'Neil, Megan J LaPorte, Christina M Monaco, Jeffrey P Cheng, Patricia B de la Tremblaye, Naima Lajud, Corina O Bondi, Anthony E Kline
Environmental enrichment (EE) promotes behavioral recovery after experimental traumatic brain injury (TBI). However, the chronic rehabilitation provided in the laboratory is not analogous to the clinic where physiotherapy is typically limited. Moreover, females make up approximately 40% of the clinical TBI population, yet they are seldom studied in brain trauma. Hence, the goal of this study was to test the hypothesis that abbreviated EE would confer neurobehavioral, cognitive, and histological benefits in brain injured female rats...
December 2016: Experimental Neurology
https://www.readbyqxmd.com/read/27685331/pain-severity-reduction-in-subjects-with-knee-osteoarthritis-decreases-motor-cognitive-dual-task-costs
#8
Dennis Hamacher, Margit Rudolf, Christoph Lohmann, Lutz Schega
BACKGROUND: Pain has disruptive effects on cognitive functions leading to a decreased capability to multi task. This might be the reason why pain is a fall risk factor in dual-task situations. This study aims to relate a decrease/increase in pain severity with a decrease/increase in dual-task costs of gait variability, which is associated with fall risk, in patients with osteoarthritis prior to and 6-8weeks after total knee replacement. METHODS: We assessed the variability of minimum toe clearance in normal walking and dual-task walking in 36 patients (14 male and 22 female participants; age=mean 64...
September 22, 2016: Clinical Biomechanics
https://www.readbyqxmd.com/read/27662775/human-factors-analysis-of-the-cardioquick-patch%C3%A2-a-novel-engineering-solution-to-the-problem-of-electrode-misplacement-during-12-lead-electrocardiogram-acquisition
#9
Raymond R Bond, Dewar D Finlay, James McLaughlin, Daniel Guldenring, Andrew Cairns, Alan Kennedy, Robert Deans, Albert L Waldo, Aaron Peace
INTRODUCTION: The CardioQuick Patch® (CQP) has been developed to assist operators in accurately positioning precordial electrodes during 12-lead electrocardiogram (ECG) acquisition. This study describes the CQP design and assesses the device in comparison to conventional electrode application. METHODS: Twenty ECG technicians were recruited and a total of 60 ECG acquisitions were performed on the same patient model over four phases: (1) all participants applied single electrodes to the patient; (2) all participants were then re-trained on electrode placement and on how to use the CQP; (3) participants were randomly divided into two groups, the standard group applied single electrodes and the CQP group used the CQP; (4) after a one day interval, the same participants returned to carry out the same procedure on the same patient (measuring intra-practitioner variability)...
August 18, 2016: Journal of Electrocardiology
https://www.readbyqxmd.com/read/27541721/emergency-manual-uses-during-actual-critical-events-and-changes-in-safety-culture-from-the-perspective-of-anesthesia-residents-a-pilot-study
#10
Sara N Goldhaber-Fiebert, Justin Pollock, Steven K Howard, Sylvia Bereknyei Merrell
BACKGROUND: Emergency manuals (EMs), context-relevant sets of cognitive aids or crisis checklists, have been used in high-hazard industries for decades, although this is a nascent field in health care. In the fall of 2012, Stanford clinically implemented EMs, including hanging physical copies in all Stanford operating rooms (ORs) and training OR clinicians on the use of, and rationale for, EMs. Although simulation studies have shown the effectiveness of EMs and similar tools when used by OR teams during crises, there are little data on clinical implementations and uses...
September 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27527391/effects-of-dexmedetomidine-on-postoperative-cognitive-dysfunction-and-serum-levels-of-b-amyloid-and-neuronal-microtubule-associated-protein-in-orthotopic-liver-transplantation-patients
#11
Guang Xu, Lan-Lan Li, Zhen-Tao Sun, Wei Zhang, Xue-Ping Han
BACKGROUND Because of the restricted data available on patients with postoperative cognitive dysfunction (POCD) in orthotopic liver transplantation (OLT), the goal of our study was to determine the outcome of dexmedetomidine (DEX) on POCD and the mechanism operating in OLT patients. MATERIAL AND METHODS Our study included 80 patients randomly divided into 2 equal groups: the DEX group and the control group. In the DEX group, our patients received an initial dose of DEX at 1 µg/kg for 10 min followed by a continuous infusion at 0...
2016: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/27519617/independence-and-health-related-quality-of-life-in-200-onco-geriatric-surgical-patients-within-6-months-of-follow-up-who-is-at-risk-to-lose
#12
P Baier, G Ihorst, G Wolff-Vorbeck, M Hüll, U Hopt, B Deschler
AIMS: Comprehensive Geriatric Assessment (CGA) provides information on aspects of older patients to predict risks and benefits of interventions. METHODS: To evaluate the application of CGA (including quality of life (QOL)) for the risk prediction of postoperative dependence and QOL in elderly patients with malignant tumours, a prospective observational study including 200 patients >70 years was performed. The primary outcome was postoperative activities of daily living (ADL < 95), secondary outcome was QOL at 6 months...
July 30, 2016: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27509465/does-surgery-for-adult-spinal-deformity-affect-the-cognitive-abilities-in-patients-over-50-years-of-age
#13
Vugar Nabiyev, Selim Ayhan, Selcen Yuksel, Asli Niyazi, Tiro Mmopelwa, Montse Domingo-Sabat, Alba Vila-Casademunt, Ferran Pellise, Ahmet Alanay, Francisco J Perez-Grueso, Frank Kleinstück, Ibrahim Obeid, Emre Acaroglu, European Spine Study Group
AIM: To analyze the cognitive abilities of older patients undergoing spinal deformity surgery so as to understand whether adult spinal deformity (ASD) surgery is associated with postoperative cognitive malfunction. MATERIAL AND METHODS: A prospective longitudinal study was performed on surgical patients older than 50 years, enrolled in a prospective multicenter database. Mini-mental state examination (MMSE) was performed to assess cognitive function in addition to the HRQOL tests; (SF-36, ODI and SRS-22) at pre-operative, post-operative 6 weeks and 6 months points...
June 24, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27462287/cognitive-effects-of-mindfulness-training-results-of-a-pilot-study-based-on-a-theory-driven-approach
#14
Lena Wimmer, Silja Bellingrath, Lisa von Stockhausen
The present paper reports a pilot study which tested cognitive effects of mindfulness practice in a theory-driven approach. Thirty-four fifth graders received either a mindfulness training which was based on the mindfulness-based stress reduction approach (experimental group), a concentration training (active control group), or no treatment (passive control group). Based on the operational definition of mindfulness by Bishop et al. (2004), effects on sustained attention, cognitive flexibility, cognitive inhibition, and data-driven as opposed to schema-based information processing were predicted...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27453368/postoperative-amplitude-integrated-electroencephalography-predicts-four-year-neurodevelopmental-outcome-in-children-with-complex-congenital-heart-disease
#15
Beatrice Latal, Gabriele Wohlrab, Barbara Brotschi, Ingrid Beck, Walter Knirsch, Vera Bernet
OBJECTIVES: To evaluate the predictive value of pre- and postoperative amplitude-integrated electroencephalography (aEEG) on neurodevelopmental outcomes in children operated for congenital heart disease (CHD). STUDY DESIGN: Prospectively enrolled cohort of 60 infants with CHD who underwent cardiac surgery with cardiopulmonary bypass in the first 3 months of life. Infants with a genetic comorbidity were excluded. aEEG was assessed for 12 hours pre- and 48 hours postoperatively...
November 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27341529/associations-between-delirium-and-preoperative-cerebrospinal-fluid-c-reactive-protein-interleukin-6-and-interleukin-6-receptor-in-individuals-with-acute-hip-fracture
#16
Bjørn Erik Neerland, Roanna J Hall, Ingebjørg Seljeflot, Frede Frihagen, Alasdair M J MacLullich, Johan Raeder, Torgeir Bruun Wyller, Leiv Otto Watne
OBJECTIVES: To examine whether delirium in individuals with hip fracture is associated with high C-reactive protein (CRP), interleukin-6 (IL-6), and soluble IL-6 receptor (sIL-6R) levels in the cerebrospinal fluid (CSF). DESIGN: Prospective cohort study. SETTING: Two university hospitals in Oslo, Norway, and Edinburgh, United Kingdom. PARTICIPANTS: Individuals admitted with acute hip fracture (N = 151). MEASUREMENTS: Participants were assessed for delirium pre- and postoperatively using the Confusion Assessment Method...
July 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27311914/protocol-for-the-electroencephalography-guidance-of-anesthesia-to-alleviate-geriatric-syndromes-engages-study-a-pragmatic-randomised-clinical-trial
#17
T S Wildes, A C Winter, H R Maybrier, A M Mickle, E J Lenze, S Stark, N Lin, S K Inouye, E M Schmitt, S L McKinnon, M R Muench, M R Murphy, R T Upadhyayula, B A Fritz, K E Escallier, G P Apakama, D A Emmert, T J Graetz, T W Stevens, B J Palanca, R L Hueneke, S Melby, B Torres, J Leung, E Jacobsohn, M S Avidan
INTRODUCTION: Postoperative delirium, arbitrarily defined as occurring within 5 days of surgery, affects up to 50% of patients older than 60 after a major operation. This geriatric syndrome is associated with longer intensive care unit and hospital stay, readmission, persistent cognitive deterioration and mortality. No effective preventive methods have been identified, but preliminary evidence suggests that EEG monitoring during general anaesthesia, by facilitating reduced anaesthetic exposure and EEG suppression, might decrease incident postoperative delirium...
June 15, 2016: BMJ Open
https://www.readbyqxmd.com/read/27238988/frailty-and-geriatric-syndromes-in-vascular-surgical-ward-patients
#18
Prudence J McRae, Philip J Walker, Nancye M Peel, Denise Hobson, Fiona Parsonson, Peter Donovan, Michael C Reade, Louise Marquart, Alison M Mudge
BACKGROUND: Preoperative frailty is an important predictor of poor outcomes but the relationship between frailty and geriatric syndromes is less clear. The aims of this study were to describe the prevalence of frailty and incidence of geriatric syndromes in a cohort of older vascular surgical ward patients, and investigate the association of frailty and other key risk factors with the occurrence of one or more geriatric syndromes (delirium, functional decline, falls, and/or pressure ulcers) and two hospital outcomes (acute length of stay and discharge destination)...
August 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27212773/comparison-of-intranasal-dexmedetomidine-and-dexmedetomidine-ketamine-for-premedication-in-pediatrics-patients-a-randomized-double-blind-study
#19
Ravi Bhat, M C B Santhosh, Venkatesh M Annigeri, Raghavendra P Rao
BACKGROUND: Goal of premedication in pediatric anesthesia are relieving pre and postoperative anxiety, good parental separation, and smooth induction of anesthesia. Anxiety can produce aggressive reactions, increased distress, increased postoperative pain and postoperative agitation. The benzodiazepine, midazolam, is the most frequently used premedication in pediatric anesthesia. Midazolam has a number of beneficial effects when used as premedication in children: Sedation, fast onset, and limited duration of action...
May 2016: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/27188598/longitudinal-brain-structural-alterations-and-systemic-inflammation-in-obstructive-sleep-apnea-before-and-after-surgical-treatment
#20
Wei-Che Lin, Chih-Cheng Huang, Hsiu-Ling Chen, Kun-Hsien Chou, Pei-Chin Chen, Nai-Wen Tsai, Meng-Hsiang Chen, Michael Friedman, Hsin-Ching Lin, Cheng-Hsien Lu
BACKGROUND: Systemic inflammation, neurocognitive impairments, and morphologic brain changes are associated with obstructive sleep apnea (OSA). Understanding their longitudinal evolution and interactions after surgical treatment provides clues to the pathogenesis of cognitive impairment and its reversibility. In the present study, we investigate clinical disease severity, systemic inflammation, cognitive deficits, and corresponding gray matter volume (GMV) changes in OSA, and the modifications following surgery...
2016: Journal of Translational Medicine
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