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https://www.readbyqxmd.com/read/29629977/clinicopathologic-features-and-genetic-alterations-of-a-primary-osteosarcoma-of-the-uterine-corpus
#1
Gang Zheng, Abby Richmond, Chengbao Liu, Alexander Berrebi, Aparna Pallavajjala, Lisa Haley, Rebecca L Stone, Edward McCarthy, Russell Vang, Deyin Xing
Primary osteosarcoma (OS) of the uterus is distinctly rare. We report a case of primary uterine OS with pulmonary metastasis in a 74-yr-old woman. Histopathologic features of the uterine tumor were in keeping with a pure chondroblastic OS composed of neoplastic cells with osteoblastic/chondroblastic differentiation and neoplastic bone formation. Despite treatment with Doxorubicin and Olaratumab and later with palliative radiation therapy, the patient died 7 mo after hysterectomy due to multiple distant metastases...
April 6, 2018: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/29581630/minimally-invasive-management-of-delayed-recognition-iatrogenic-ureteric-injury
#2
Jessica Morrow, David Curry, Maeve Dooher, Siobhan Woolsey
Introduction: Iatrogenic ureteric injuries are a rare but serious complication of abdomino-pelvic surgery which can be associated with significant morbidity. 65-80% of ureteric trauma is only identified in the postoperative period. Current guidelines recommend stent insertion or urinary diversion via percutaneous nephrostomy. Good quality evidence on success and outcomes remains scant and the optimum treatment pathway unknown. Methods: A retrospective review of all delayed presentation ureteric injuries treated in our unit between 2005 and 2013 was performed...
September 2017: Ulster Medical Journal
https://www.readbyqxmd.com/read/29538195/one-stage-surgery-for-removal-of-intravascular-leiomyomatosis-extending-to-right-ventricle
#3
Ching-Shu Chiang, Po-Lin Chen, Tzu-Ting Kuo, I-Ming Chen, Nai-Yuan Wu, Hsiao-Huang Chang
RATIONALE: Intravascular leiomyomatosis (IVL) is a rare nonmalignant tumor that can be fatal if untreated. PATIENT CONCERNS: A 49-year-old nulliparous Asian woman who underwent hysterectomy and left salpingo-oophorectomy for multiple uterine leiomyomas 18 months prior presented complaining of intermittent palpitation and chest tightness for approximately 1 month. Echocardiography revealed a large mobile tumor mass extending from the inferior vena cava (IVC) to the right atrium that partially obstructed IVC flow and tricuspid inflow...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29515415/long-lasting-response-to-trabectedin-in-a-patient-with-metastatic-uterine-leiomyosarcoma-a-case-report
#4
Viktoria-Anna Nteli, Wolfgang Knauf, Anja Janton-Klein, Samer El-Safadi
Background: Uterine leiomyosarcoma (uLMS) is a rare tumor that accounts for 1% of all uterine malignancies. In spite of adequate surgical resection of uLMS, even in the early stage, patients remain at high risk for local and distant recurrence. Therefore, the treatment of advanced uLMS represents a considerable challenge. Methods: We report the case of a 47-year-old woman who presented with uLMS with abnormal vaginal bleeding. Results: The patient underwent a total hysterectomy and bilateral adnexectomy, which was followed by 1 year progression-free survival without adjuvant therapy...
January 2018: Case Reports in Oncology
https://www.readbyqxmd.com/read/29480840/clinical-management-of-a-unique-case-of-pnet-of-the-uterus-during-pregnancy-and-review-of-the-literature
#5
REVIEW
Rosalba De Nola, Edoardo Di Naro, Luca Maria Schonauer, Giuseppe Lucarelli, Michele Battaglia, Maria Grazia Fiore, Salvatore Andrea Mastrolia, Giuseppe Loverro
RATIONALE: PNETs (primitive neuroectodermal tumors) are a family of highly malignant neoplasms characterized by small round cells of neuroepithelial origin. They usually involve bone and soft tissues, and have a higher incidence in childhood. PATIENT CONCERNS: In this case report, we describe the obstetric and oncological outcome of a huge mass diagnosed as a leiomyoma in a 39-year-old pregnant woman who complained of low back pain, dysuria, and urinary frequency at 22 weeks of gestation...
January 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29400419/endometrioid-carcinoma-arising-from-diaphragmatic-endometriosis-treated-with-laparoscopy-a-case-report
#6
Hiroyuki Okimura, Hiroshi Tatsumi, Fumitake Ito, Suguru Yamashita, Tetsuya Kokabu, Jo Kitawaki
Malignant transformation of diaphragmatic endometriosis is rare. We present a case of endometrioid carcinoma arising from diaphragmatic endometriosis treated with laparoscopy. A 59-year-old primigravida woman who had undergone abdominal hysterectomy for adenomyosis at the age of 47 years was referred to our hospital for investigation of a tumor on the surface of the liver. An integrated positron emission tomography-computed tomography scan revealed a 3-cm nodule on the surface of the liver with abnormal fluorine-18-deoxyglucose accumulation...
February 5, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29394693/-combination-treatments-to-the-huge-ovarian-cancer-with-liver-metastases
#7
Yasunori Hasuike, Yasushi Kanaoka, Ichiro Higuchi, Hirosumi Imoto, Sanae Hosomi, Akira Ishikawa, Yosuke Akiyama, Takahiko Tanigawa, Makoto Miyamoto
We report a CR case of huge ovarian cancer with peritoneal and liver metastases who was operated bilateral ovaries, uterus and peritoneal metastases at first, followed by systemic chemotherapy and performed 4 times of radiofrequency ablation (RFA)and 2 times of liver resection(LR). The case was a 50-year-old woman. She suffered with bowel enlargement from over 1 year ago. Preoperative MRI finding was huge ovarian serous cyst with partial solid tumor inside. The major axis was about 30 cm. CA125 and CA19-9 levels were elevated...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394659/-a-resected-case-of-the-vaginal-metastasis-from-rectal-cancer
#8
Akinobu Yasuyama, Shingo Noura, Tae Matsumura, Masanori Hirota, Akihiro Takada, Chikato Koga, Chizu Kameda, Masahiro Murakami, Ryohei Kawabata, Junzo Shimizu, Junichi Hasegawa
The vaginal metastasis from colorectal cancer has rarely been reported. Here, we report a resected case of the vaginal metastasis from rectal cancer. A 51-year-old woman underwent radical hysterectomy and bilateral oophorectomy for uterus cancer. Five years after the operation, vaginal tumor was observed during an internal examination. Biopsy was positive for adenocarcinoma. Enhanced computed tomography demonstrated the wall thickening of the lower rectum and the mass of 20 mm at the inferior lobe of the left lung...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394557/-two-resected-cases-of-non-isolated-splenic-metastasis-of-colon-cancer
#9
Hikaru Watanabe, Hideki Osawa, Keigo Yasumasa, Yuhi Shimura, Ryugo Teranishi, Marie Todo, Shohei Takaichi, Chihyon Son, Kenji Sakai, Hiroshi Noro, Takafumi Hirao, Teruo Iwasaki, Nobutaka Hatanaka, Yoshio Yamasaki
We report 2 resected cases of patients with non-isolated splenic metastasis of colon cancer. Case 1: A 67-year-old man who underwent partial transverse colectomy and partial hepatectomy for transverse colon cancer and liver metastasis. Approximately 18 months after the operation, splenectomy and partial hepatectomy were performed for metastasis to the spleen and liver. After partial hepatectomy for another recurrence, no signs of new recurrence have been observed for 42 months after splenectomy. Case 2: A 53-year-old woman who presented with bloating...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29374658/protocol-for-compass-a-randomised-controlled-trial-of-primary-hpv-testing-versus-cytology-screening-for-cervical-cancer-in-hpv-unvaccinated-and-vaccinated-women-aged-25-69-years-living-in-australia
#10
Karen Canfell, Marion Saville, Michael Caruana, Val Gebski, Jessica Darlington-Brown, Julia Brotherton, Stella Heley, Philip E Castle
INTRODUCTION: Australia's National Cervical Screening Program (NCSP) currently recommends 2-year cytology in women aged 18-69 years. Following a review of the NCSP prompted by the implementation of human papillomavirus (HPV) vaccination, the programme will transition in 2017 to 5-year primary HPV screening with partial genotyping for HPV16/18 in women aged 25-74 years. Compass is a sentinel experience for the renewed NCSP and the first prospectively randomised trial of primary HPV screening compared with cytology to be conducted in a population with high uptake of HPV vaccination...
January 26, 2018: BMJ Open
https://www.readbyqxmd.com/read/29351618/maintenance-hormonal-therapy-after-treatment-with-medroxyprogesterone-acetate-for-patients-with-atypical-polypoid-adenomyoma
#11
Hidetaka Nomura, Yuko Sugiyama, Terumi Tanigawa, Maki Matoda, Sanshiro Okamoto, Kohei Omatsu, Hiroyuki Kanao, Kazuyoshi Kato, Kuniko Utsugi, Nobuhiro Takeshima
Background: As atypical polypoid adenomyoma (APA) has been reported to be a hormone-related tumor, we aimed to analyze the efficacy and safety of maintenance hormonal therapy after fertility-preserving treatment of these patients with medroxyprogesterone acetate (MPA). Methods: Data were retrospectively analyzed from patients with APA who were treated with a fertility-preserving regimen including MPA between October 2001 and December 2011. Eighteen patients were treated with MPA and 14 (77...
March 1, 2018: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29237906/clinical-efficacy-of-preoperative-vaginal-intracavitary-irradiation-for-stage-ib2-and-iia-cervical-cancer
#12
Fengshuang Li, Yumei Wu, Weimin Kong, Jiandong Wang, Xia Hao, Juwei Niu, Laifu Bai
OBJECTIVE: The purpose of this study was to evaluate the clinical efficacy of preoperative vaginal intracavitary irradiation for Stage Ib2 and IIa cervical cancer. MATERIALS AND METHODS: From June 2008 to June 2014, data from 78 Stage Ib2 and IIa cervical cancer patients (age ≤75 years) with a diameter of local lesions >4 cm were collected in our hospital. Before treatment, all cases were confirmed by biopsy. The patients' general state was good, Karnofsky Performance Score ≥90, heart and lung functioning was normal, and patients were able to tolerate the surgery...
2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29219861/sacrocolpopexy-with-concomitant-total-vs-supracervical-hysterectomy-functional-support-comparisons-in-cadavers
#13
Pedro Antonio Maldonado, Kyle P Norris, Maria E Florian-Rodriguez, Nemi M Shah, Clifford Y Wai
OBJECTIVE: This study aimed to compare the ability of abdominal sacrocolpopexy (ASC) with concomitant total vs supracervical hysterectomy to resist downward traction as a measure of functional anatomic support in human cadavers. METHODS: Supracervical hysterectomy was performed on unembalmed cadaver specimens, followed by ASC attaching polypropylene mesh to the posterior cervix/vagina only and then the anterior and posterior cervix/vagina. Using a metal bolt placed through the cervix tied to a filament passing through a fixed pulley system, successive weights of 0...
December 7, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29207786/recurrent-vaginal-cuff-dehiscence-in-a-treated-case-of-carcinoma-cervix
#14
Sunesh Kumar, Seema Singhal, Yamini Kansal, Dayanand Sharma
Vaginal Cuff Dehiscence (VCD) is partial or total separation of anterior and posterior vaginal cuff layers. We report a case of recurrent vault cuff dehiscence in a patient of cervical carcinoma. A 60-year-old treated case of carcinoma cervix post surgery and radiotherapy was found to have vault dehiscence and intestinal prolapse second time during a routine speculum examination. She underwent an emergency laparotomy and closure of vault. Vaginal Cuff Dehiscence with Evisceration (VCDE) is a rare but potentially fatal complication following hysterectomy...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29162957/geriatric-pelvic-organ-prolapse-surgery-going-the-extra-mile
#15
Seethalakshmi Krishnan
Background: To assess the quality of life in geriatric patients after reconstructive and obliterative vaginal surgery for advanced pelvic organ prolapse (POP). Methods: Prospective observational study was conducted between January 2009 and December 2014 at the department of Urogynaecology, Government Kasturbha Gandhi Hospital. A total of 424 women (between the age group of 60 and 94 years) with advanced pelvic organ prolapse underwent vaginal hysterectomy along with vaginal apical suspension procedures which were McCalls culdoplasty (35...
December 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29145778/an-apparent-case-of-brodifacoum-toxicosis-in-a-whelping-dog
#16
Scott D Fitzgerald, Jennifer Martinez, John P Buchweitz
A 7-y-old Weimaraner bitch was presented to emergency service after 3 h of active labor with no puppies produced. Hemoabdomen and hemothorax were present at the time of surgery; prothrombin time (PT) and activated partial thromboplastin time (aPTT) were both found to be within normal ranges. Surgical cesarean section was performed; 4 dead puppies and 5 live puppies were delivered. Because hemostasis was difficult to achieve, a hysterectomy was performed; however, the dog died as the operation was being completed...
January 2018: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/29105982/trends-in-the-diffusion-of-robotic-surgery-a-retrospective-observational-study
#17
Hani J Marcus, Archie Hughes-Hallett, Christopher J Payne, Thomas P Cundy, Dipankar Nandi, Guang-Zhong Yang, Ara Darzi
BACKGROUND: Recent studies have suggested that the use of robotic surgery for prostatectomy has been increasing, but characterization of the diffusion of robotic surgery in other procedures has not been available. METHODS: Data were analysed for the years 2006-2014 using hospital episode statistics (HES), a database of all admissions to National Health Service (NHS) hospitals in England. OPCS codes were used to determine the annual number of prostatectomy, partial nephrectomy, and total abdominal hysterectomy procedures...
December 2017: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/28975434/high-intensity-focused-ultrasound-hifu-treatment-for-uterine-fibroids-a-meta-analysis
#18
Yongshuo Ji, Kaimeng Hu, Yu Zhang, Lijun Gu, Junqiu Zhu, Linglin Zhu, Yanfei Zhu, Hong Zhao
PURPOSE: High-intensity focused ultrasound (HIFU) is a non-invasive uterine-preserving treatment alternative to hysterectomy for women with fibroids. METHODS: We performed this meta-analysis to evaluate the efficacy of HIFU in the treatment of women with symptomatic fibroids comparing it to other approaches including medical treatment with mifepristone (Mife), traditional surgery with myomectomy or hysterectomy (MYC/HRM), and radiofrequency ablation (RF). 16 studies with 1725 women were included...
October 3, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28781816/bevacizumab-plus-chemotherapy-continued-beyond-progression-in-patients-with-type-ii-endometrial-cancer-previously-treated-with-bevacizumab-plus-chemotherapy-a-case-report
#19
Emi Sato, Kentaro Nakayama, Kohei Nakamura, Tomoka Ishibashi, Hiroshi Katagiri, Masako Ishikawa, Satoru Kyo
The prognosis of patients with recurrent/persistent endometrial cancer, particularly type II cancer, remains poor, and effective treatment has not yet been established. We herein present the case of a patient with recurrent type II endometrial cancer who received bevacizumab + chemotherapy continued beyond progression, after previously receiving bevacizumab + chemotherapy. This patient experienced recurrence after first- and second-line adjuvant chemotherapy followed by modified radical hysterectomy and she was administered bevacizumab + paclitaxel + carboplatin therapy...
September 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28751235/laparoscopic-uterovaginal-anastomosis-for-cervical-agenesis-a-case-report
#20
Ameya Padmawar, Rizwana Syed, Suyash Naval
STUDY OBJECTIVE: To demonstrate possibility of an innovative surgery for management of cervical agenesis. DESIGN: Step wise description of laparoscopic uterovaginal anastomosis. SETTING: Isolated cervical agenesis occurs in 1 in 80000 to 100000 births. According to the American Fertility Society, cervical agenesis should be classified as a type Ib müllerian anomaly. According to ESHRE/ESGE classification, it is classified in class C4 category...
July 24, 2017: Journal of Minimally Invasive Gynecology
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