keyword
MENU ▼
Read by QxMD icon Read
search

antibacterials

keyword
https://www.readbyqxmd.com/read/28544966/antibacterial-property-and-biocompatibility-of-chitosan-poly-vinyl-alcohol-zno-cs-pva-zno-beads-as-an-efficient-adsorbent-for-cu-ii-removal-from-aqueous-solution
#1
Jiao Xu, Yaping Zhang, Yuvaraja Gutha, Weijiang Zhang
The feasibility of using chitosan/Poly(vinyl alcohol)/ZnO beads (CS/PVA/ZnO) as an adsorbent for removal of Cu(II) ions from aqueous solutions was studied in a batch method. The developed adsorbent material was characterized by XRD, FTIR, SEM and TEM analysis. Pure ZnO shows the characteristic peaks at (100), (002), (101), (102), (110), (103), (200) and (112) that were in good agreement with wurtzite ore having hexagonal lattice structure. Antibacterial properties and biocompatibility of the CS/PVA/ZnO was tested...
May 11, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28544494/4-substituted-thieno-2-3-d-pyrimidines-as-potent-antibacterial-agents-rational-design-microwave-assisted-synthesis-biological-evaluation-and-molecular-docking-studies
#2
Rupinder K Gill, Harpreet Singh, Tilak Raj, Anuradha Sharma, Gagandeep Singh, Jitender Bariwal
In an attempt to discover a new class of antibacterial agents with improved efficacy and to overcome the drug resistant problems, some novel 4-substituted thieno[2,3-d]pyrimidines have been synthesized via microwave assisted methodology and evaluated for their in vitro antibacterial activity against various pathogenic bacterial strains. Compounds 12b and 13c showed the promising inhibitory potencies against S. aureus, B. subtilis, P. aeruginosa and E. coli with MICs ranging from 2 to 10 μg/ml. Compound 13c was also found to be highly potent against methicillin resistant S...
May 23, 2017: Chemical Biology & Drug Design
https://www.readbyqxmd.com/read/28542863/mechanisms-of-silver-diamine-fluoride-on-arresting-caries-a-literature-review
#3
REVIEW
Irene Shuping Zhao, Sherry Shiqian Gao, Noriko Hiraishi, Michael Francis Burrow, Duangporn Duangthip, May Lei Mei, Edward Chin-Man Lo, Chun-Hung Chu
OBJECTIVE: To review the evidence regarding the mechanisms of silver diamine fluoride (SDF) for arresting caries. METHODS: A literature search was conducted using the keywords silver diamine fluoride, and its alternative names, in seven databases: PubMed, Embase and Scopus (English); China National Knowledge Infrastructure (Chinese); Bilioteca Virtual em Saude (Portuguese); Biblioteca Virtual en Salud Espana (Spanish); and Ichushi-Web (Japanese). The titles and abstracts were screened...
May 21, 2017: International Dental Journal
https://www.readbyqxmd.com/read/28542390/analysis-of-early-mesothelial-cell-responses-to-staphylococcus-epidermidis-isolated-from-patients-with-peritoneal-dialysis-associated-peritonitis
#4
Amanda L McGuire, Kieran T Mulroney, Christine F Carson, Ramesh Ram, Grant Morahan, Aron Chakera
The major complication of peritoneal dialysis (PD) is the development of peritonitis, an infection within the abdominal cavity, primarily caused by bacteria. PD peritonitis is associated with significant morbidity, mortality and health care costs. Staphylococcus epidermidis is the most frequently isolated cause of PD-associated peritonitis. Mesothelial cells are integral to the host response to peritonitis, and subsequent clinical outcomes, yet the effects of infection on mesothelial cells are not well characterised...
2017: PloS One
https://www.readbyqxmd.com/read/28542279/oligopeptides-as-full-length-new-delhi-metallo-%C3%AE-lactamase-1-ndm-1-inhibitors
#5
Bingzheng Shen, Chengliang Zhu, Xiang Gao, Gang Liu, Jinchun Song, Yan Yu
'Superbug' bacteria producing NDM-1 enzyme causing wide public concern were first detected in a patient who visited India in 2008. It's an effective approach to combining β-lactam antibiotics with NDM-1 inhibitor for treating NDM-1 producing strain infection. In our research, we designed ten oligopeptides, tested IC50 values against NDM-1 enzyme, determined the MIC values of synergistic antibacterial effect and explored the binding model. We found that the oligopeptides 2 (Cys-Phe) and 5 (Cys-Asp) respectively presented IC50 values of 113 μM and 68 μM and also displayed favorable synergistic effects of the inhibitors in combination with ertapenem against genetic engineering-host E...
2017: PloS One
https://www.readbyqxmd.com/read/28541828/simple-green-production-of-silver-nanoparticles-facilitated-by-bacterial-genomic-dna-and-their-antibacterial-activity
#6
Jiraporn Chumpol, Sineenat Siri
Green synthesis of AgNPs has gained many research interests as a low cost and eco-friendly approach. This work reported on the use of bacterial genomic DNA as the alternative biopolymer for a green production of AgNPs under a neutral pH. Although both ssDNA and dsDNA could function as stabilizing agents during the synthesis process, the ssDNA, generated by pre-heating the dsDNA at 100 °C, was more efficient to produce AgNPs with higher yield as determined by the intensity of the surface plasmon resonance (SPR) peak of silver at 475 nm...
May 25, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/28541741/green-approach-for-synthesis-of-gold-nanoparticles-from-nigella-arvensis-leaf-extract-and-evaluation-of-their-antibacterial-antioxidant-cytotoxicity-and-catalytic-activities
#7
Azam Chahardoli, Naser Karimi, Fatemeh Sadeghi, Ali Fattahi
In the present work, we studied the reduction of gold ions into gold nanoparticles using Nigella arvensis leaf extract in the one-step green synthesis method. The formation of N. arvensis gold nanoparticles (NA-GNPs) was confirmed by UV-Vis spectroscopy, XRD, FT-IR and TEM analyses. The XRD pattern confirmed the crystal structure of NA-GNPs, and TEM image showed the small size (3-37 nm) and almost spherical shape of NA-GNPs. NA-GNPs have not shown enhanced antioxidant properties compared to the plant extract while they were active against the clinical isolated bacterial strains...
May 25, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/28541368/fe2o3-nanoparticles-anchored-on-2d-kaolinite-with-enhanced-antibacterial-activity
#8
Mei Long, Yi Zhang, Zhan Shu, Aidong Tang, Jing Ouyang, Huaming Yang
An enhanced antibacterial activity of Fe2O3 nanoparticles was achieved by controlling the distribution density of Fe2O3 nanoparticles on modified kaolinite nanosheets (Fe2O3-KlnKAc) by adjusting the pH value of the reaction system. A proper distribution density of Fe2O3 nanoparticles generating higher levels of hydroxyl radicals led to a higher antibacterial activity.
May 25, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28541127/screening-of-plants-with-antimicrobial-activity-against-enterobacteria-pseudomonas-spp-and-staphylococcus-spp
#9
Camila Miorelli Girondi, Analu Barros de Oliveira, Jackeline Alves Prado, Cristiane Yumi Koga-Ito, Aline Chiodi Borges, Alberto Carlos Botazzo Delbem, Daniel Freitas Alves Pereira, Marcos José Salvador, Fernanda Lourenção Brighenti
AIM: This study screened plants for antibacterial properties against bacteria of medical importance. MATERIALS & METHODS: 60 extracts were obtained from the leaves of ten plants (Jatropha weddelliana, Attalea phalerata, Buchenavia tomentosa, Croton doctoris, Mouriri elliptica, Mascagnia benthamiana, Senna aculeata, Unonopis guatterioides, Allagoptera leucocalyx and Bactris glaucescens) using different extraction methods: A) Ethanol 70°C/72 h; B) Water/5 min/100°C; C) Water/1 h/55°C; D) Water/72 h; E) Hexane/72 h and F) Ethanol 99°C/72 h...
May 25, 2017: Future Microbiology
https://www.readbyqxmd.com/read/28541047/multitargeted-flavonoid-inhibition-of-the-pathogenic-bacterium-staphylococcus-aureus-a-proteomic-characterization
#10
Wael A Elmasri, Rui Zhu, Wenjing Peng, Moustafa Al-Hariri, Firas Kobeissy, Phat Tran, Abdul N Hamood, Mohamed F Hegazy, Paul W Paré, Yehia Mechref
Growth inhibition of the pathogen Staphylococcus aureus with currently available antibiotics is problematic in part due to bacterial biofilm protection. Although recently characterized natural products, including 3',4',5-trihydroxy-6,7-dimethoxy-flavone [1], 3',4',5,6,7-pentahydroxy-flavone [2], and 5-hydroxy-4',7-dimethoxy-flavone [3], exhibit both antibiotic and biofilm inhibitory activities, the mode of action of such hydroxylated flavonoids with respect to S. aureus inhibition is yet to be characterized...
May 25, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28541042/combinatorial-biosynthesis-of-daurichromenic-acid-and-its-halogenated-analogue
#11
Masahiro Okada, Kai Saito, Chin Piow Wong, Chang Li, Dongmei Wang, Miu Iijima, Futoshi Taura, Fumiya Kurosaki, Takayoshi Awakawa, Ikuro Abe
Daurichromenic acid is a meroterpenoid with various pharmacological activities that is biosynthesized from grifolic acid in Rhododendron dauricum. Heterologous expression of grifolic acid synthases from Stachybotrys bisbyi and a daurichromenic acid synthase from R. dauricum in Aspergillus oryzae mediated three-step combinatorial biosynthesis of (+)-daurichromenic acid through enantioselective 6-endo-trig cyclization. Additional introduction of a halogenase from Fusarium sp. into the strain resulted in the biosynthesis of (+)-5-chlorodaurichromenic acid, which exceeds the antibacterial activity of the original compounds...
May 25, 2017: Organic Letters
https://www.readbyqxmd.com/read/28540723/a-high-throughput-fabrication-method-to-produce-a-silver-nanoparticles-doped-nanoclay-polymer-composite-with-novel-synergistic-antibacterial-effects-at-the-material-interface
#12
Shaobo Cai, Behnam Pourdeyhimi, Elizabeth G Loboa
In this study, we report a high throughput fabrication method at industrial pilot scale to produce a silver nanoparticles-doped-nanoclay/polylactic acid composite with a novel synergistic antibacterial effect. The obtained nanocomposite has a significantly lower affinity for bacterial adhesion, allowing the loading amount of silver nanoparticles to be tremendously reduced while maintaining satisfactory antibacterial efficacy at the material interface. This is a great advantage for many antibacterial applications where cost is a consideration...
May 25, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28540651/biologically-active-cu-ii-co-ii-ni-ii-and-zn-ii-complexes-of-pyrimidine-derivative-schiff-base-dna-binding-antioxidant-antibacterial-and-in-vitro-anticancer-studies
#13
Nagaraj Revathi, Murugesan Sankarganesh, Jegathalaprathaban Rajesh, Jeyaraj Dhaveethu Raja
A new pyrimidine derivative Schiff base ligand (HL) [HL = 2-(4,6-dimethylpyrimidin-2-ylimino)methyl)-4-nitrophenol] and its metal(II) complexes [CuL2] (1), [CoL2] (2), [NiL2] (3) and [ZnL2] (4) have been synthesized and characterized by several spectral techniques. The square planar geometry of the complexes 1-4 confirmed by UV-Visible, ESR and EI-mass spectral techniques. DNA binding study of the complexes 1-4 with Calf Thymus (CT) DNA using absorption spectral titration at different pH (4.0, 7.0 & 10.0) have been scrutinized that the complexes 1-4 bound by groove binding mode with significant binding constant values (K b  = 5...
May 24, 2017: Journal of Fluorescence
https://www.readbyqxmd.com/read/28540555/plasma-activated-water-antibacterial-activity-and-artifacts
#14
Tung-Po Chen, Junfeng Liang, Tsan-Liang Su
Broad biological activities of "plasma-activated water" (PAW) have drawn great attentions recently. Treatment of water using gas discharge plasma led to acidic solutions with excellent and broad antibacterial activity. Because PAW caused severe membrane damages in bacteria and diffused freely in extracellular matrix, PAW also demonstrated good anti-biofilm activity. However, further studies revealed that trace amounts of metal ions (mainly copper and zinc) in PAW brought by plasma treatment played key roles in bacteria inactivation...
May 24, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28540272/evaluation-of-the-effects-of-local-application-of-thyme-honey-in-open-cutaneous-wound-healing
#15
Nasrin Takzaree, Gholamreza Hassanzadeh, Mohammad Reza Rouini, Azadeh Manayi, Abbas Hadjiakhondi, Masoumeh Majidi Zolbin
BACKGROUND: Clinicians have been searching for ways to obtain "super normal" wound healing. Honey is a traditional remedy for the treatment of infected wounds. We aimed to evaluate the wound contraction and antibacterial properties of locally produced Thyme honey on managing full-thickness wounds in vivo. METHODS: This experimental study was conducted in 2015, in Department of Pharmacology, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran on 54 adult male Wistar rats weighing 200-250 gr, and ages of 3-4 months...
April 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28539745/effect-of-tamarindus-indica-l-and-manihot-esculenta-extracts-on-antibiotic-resistant-bacteria
#16
Zenon Machado Lima, Lenilson Santos da Trindade, Genelane Cruz Santana, Francine Ferreira Padilha, Marcelo da Costa Mendonça, Luiz Pereira da Costa, Jorge A López, Maria Lucila Hernández Macedo
BACKGROUND: The chemical composition of plants used in traditional medicine exhibits biologically active compounds, such as tannins, flavonoids, and alkaloids and becomes a promising approach to treat microbial infections, mainly with drug-resistant bacteria. OBJECTIVE: The aim of the present study was to evaluate the hydroethanolic leaf extracts of Tamarindus indica (tamarind) and Manihot esculenta (cassava) as antimicrobial potential against Pseudomonas aeruginosa clinical isolated and Methicillin-resistant Staphylococcus aureus...
April 2017: Pharmacognosy Research
https://www.readbyqxmd.com/read/28539715/antiprotozoal-antibacterial-and-antidiarrheal-properties-from-the-flowers-of-chiranthodendron-pentadactylon-and-isolated-flavonoids
#17
Fernando Calzada, Teresa Juárez, Normand García-Hernández, Miguel Valdes, Oscar Ávila, Lilian Yepez Mulia, Claudia Velázquez
BACKGROUND: Chiranthodendron pentadactylon Larreat. (Sterculiaceae) is a Mexican plant used in traditional medicine for the treatment of heart disease symptoms and infectious diarrhea. OBJECTIVE: To evaluate in vitro antiprotozoal and antibacterial activities and in vivo antidiarrheal activity from the flowers of C. pentadactylon using the extract, fractions, and major isolated flavonoids. MATERIALS AND METHODS: Bioassay-guided fractionation of the methanol extract of C...
April 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28539266/antibacterial-cysteine-protease-from-cissus-quadrangularis-l
#18
Sakthivel Muthu, Venkatesh Babu Gopal, Narayan Karthik S, Prabu Sivaji, Sathuvan Malairaj, Mythileeswari Lakshmikanthan, Nagaraj Subramani, Palani Perumal
An antibacterial Cp was extracted from the stem of Cissus quadrangularis and purified with a 5.39 fold increase in specific activity and 8.67% recovery. The molecular weight of the purified enzyme was estimated to be 39kDa by SDS-PAGE. The purified enzyme appeared as a single band on Native-PAGE. The optimum pH and temperature for protease activity were around 6.0 and 50°C respectively. The Cp showed pH stability from 3 to 10 and retained more than 90% of its relative protease activity. The addition of metal ions such as Mg(2+) and Ca(2+) also exhibited relative protease activity...
May 21, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28539243/synthesis-sar-and-molecular-docking-studies-of-benzo-d-thiazole-hydrazones-as-potential-antibacterial-and-antifungal-agents
#19
Gao-Feng Zha, Jing Leng, N Darshini, T Shubhavathi, H K Vivek, Abdullah M Asiri, Hadi M Marwani, K P Rakesh, N Mallesha, Hua-Li Qin
A series of new benzo[d]thiazole-hydrazones analogues were synthesized and screened for their in vitro antibacterial and antifungal activities. The results revealed that compounds 13, 14, 15, 19, 20, 28 and 30 exhibited superior antibacterial potency compared to the reference drug chloramphenicol and rifampicin. Compounds 5, 9, 10, 11, 12, 28 and 30 were found to be good antifungal activity compared to the standard drug ketoconazole. A preliminary study of the structure-activity relationship (SAR) revealed that the antimicrobial activity depended on the effect of different substituents on the phenyl ring...
May 13, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28538688/in-silico-study-and-bioprospection-of-the-antibacterial-and-antioxidant-effects-of-flavone-and-its-hydroxylated-derivatives
#20
Camila de Albuquerque Montenegro, Gregório Fernandes Gonçalves, Abrahão Alves de Oliveira Filho, Andressa Brito Lira, Thays Thyara Mendes Cassiano, Natanael Teles Ramos de Lima, José Maria Barbosa-Filho, Margareth de Fátima Formiga Melo Diniz, Hilzeth Luna Freire Pessôa
Flavonoid compounds are widely used as natural protective species, which can act as anti-inflammatory, antioxidant, anticoagulant, antihypertensive and antitumor agents. This study set out to investigate the probable pharmacological activities, along with the antibacterial and antioxidant effects, of flavone and its hydroxy derivatives: 3-hydroxyflavone, 5-hydroxyflavone and 6-hydroxyflavone. To do so, we investigated their pharmacological characteristics, using in silico tests that indicate likelihood of activity or inactivity, with the PASS online software, and the antimicrobial potential against Gram positive and Gram negative bacteria was also analyzed, including bacteria of clinical importance...
May 24, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
keyword
keyword
92605
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"