Eric S Donkor, Khitam Muhsen, Sherry A M Johnson, Fleischer C N Kotey, Nicholas T K D Dayie, Patience B Tetteh-Quarcoo, Edem M A Tette, Mary-Magdalene Osei, Beverly Egyir, Nicholas I Nii-Trebi, Godfred Owusu-Okyere, Alex Owusu-Ofori, Yonatan Amir, Saritte Perlman, Perdita Hilary Lopes, Adjo Mfodwo, Nicola C Gordon, Louise Gresham, Mark Smolinski, Dani Cohen
BACKGROUND: Antimicrobial resistance (AMR) in Gram-negative bacteria-causing bloodstream infections (BSIs), such as Klebsiella pneumoniae and non-typhoidal Salmonella (NTS), is a major public health concern. Nonetheless, AMR surveillance remains scarce in sub-Saharan Africa, where BSI treatment is largely empirical. The aim of the study was to determine the distribution and AMR patterns of BSI-causing NTS, K. pneumoniae , and other Gram-negative bacteria in Ghana. METHODS: A cross-sectional study was conducted between April and December 2021 at eleven sentinel health facilities across Ghana as part of a pilot study on the feasibility and implementation of the human sector AMR surveillance harmonized protocol in sub-Saharan Africa...
January 27, 2023: Antibiotics