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https://www.readbyqxmd.com/read/28512187/neutral-competition-for-drosophila-follicle-and-cyst-stem-cell-niches-requires-vesicle-trafficking-genes
#1
Matthew S Cook, Coralie Cazin, Marc Amoyel, Shinya Yamamoto, Erika Bach, Todd Nystul
The process of selecting for cellular fitness through competition plays a critical role in both development and disease. The germarium, a structure at the tip of the ovariole of a Drosophila ovary, contains two follicle stem cells (FSCs) that undergo neutral competition for the stem cell niche. Using the FSCs as a model, we performed a genetic screen through a collection of 126 mutants in essential genes on the X chromosome to identify candidates that increase or decrease competition for the FSC niche. We identified approximately 55% and 6% of the mutations screened as putative FSC hypo- or hypercompetitors, respectively...
May 16, 2017: Genetics
https://www.readbyqxmd.com/read/28493804/hereditary-renal-cystic-disorders-imaging-of-the-kidneys-and-beyond
#2
Jonathan R Dillman, Andrew T Trout, Ethan A Smith, Alexander J Towbin
The purpose of this article is to review the hereditary renal cystic diseases that can manifest in children and adults, with specific attention to pathogenesis and imaging features. Various common and uncommon hereditary renal cystic diseases are reviewed in terms of their underlying etiology, including the involved genetic mutations and the affected proteins and cellular structures. Focus is placed on the morphologic findings in each condition and the features that distinguish one disorder from another. The two most common categories of hereditary renal cystic disease are (a) the ciliopathic disorders, which are related to mutations affecting the primary cilia (called "ciliopathies"), and (b) the phakomatoses...
May 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28491317/marathoning-with-myotonic-dystrophy-type-2-proximal-myotonic-myopathy-and-leukopenia
#3
Josef Finsterer, Georg Safoschnik, Martina Witsch-Baumgartner
OBJECTIVES: A mild, slowly progressive course of proximal myotonic myopathy, also known as myotonic dystrophy type 2, over years allowing the patient to continue with extreme sport activity, has been only rarely reported. METHODS: Case report. RESULTS: The patient is a 54-year-old female sport teacher who developed myotonia of the distal upper limbs at the age of 32 years. Over the following 22 years, myotonia spreaded to the entire musculature...
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/28486360/ovarian-mucinous-cystadenoma-after-ovarian-graft
#4
Carole Fajau-Prevot, Yann Tanguy Le Gac, Christine Chevreau, Clémentine Cohade, Nicolas Gatimel, Jean Parinaud, Roger Leandri
BACKGROUND: Freezing strips of ovarian cortex before chemotherapy followed by transplantation is an experimental method to preserve fertility for reproductive-aged women with cancer. We report a case of a cancer patient who developed a mucinous cystadenoma in a grafted piece of ovarian cortex. CASE: A 32-year-old woman with a Ewing sarcoma had ovarian cryopreservation using cortical strip freezing before receiving chemotherapy. Five years later she had no ovarian function, and the strips were thawed and grafted back onto the ovary...
May 5, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28483503/gaps-in-knowledge-among-physicians-regarding-diagnostic-criteria-and-management-of-polycystic-ovary-syndrome
#5
Anuja Dokras, Shailly Saini, Melanie Gibson-Helm, Jay Schulkin, Laura Cooney, Helena Teede
OBJECTIVE: To identify gaps in polycystic ovary syndrome (PCOS) knowledge and practice patterns among physicians in North America in response to significant dissatisfaction identified among women with PCOS regarding their diagnosis and treatment experience. DESIGN: Online survey conducted via American College of Obstetrics and Gynecology of gynecologists (ObGyn) and American Society of Reproductive Medicine of reproductive endocrinologists (REI-ObGyn) in 2015-16...
May 5, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28480536/spectrums-and-outcomes-of-adnexal-torsion-at-different-ages
#6
Jie-Ling Feng, Ting Lei, Hong-Ning Xie, Li-Juan Li, Liu Du
OBJECTIVES: To investigate the role of ultrasound in the preoperative diagnosis of adnexal torsion and describe its histological spectrum and outcomes at different ages. METHODS: This study comprised a retrospective investigation of a data set that included 195 female patients with clinically suspected adnexal torsion between January 2010 and July 2015. Each patient received a detailed pelvic ultrasound examination by an experienced ultrasound examiner, and a definitive diagnosis was achieved via surgery...
May 8, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28470574/tff3-expression-as-stratification-marker-in-borderline-epithelial-tumors-of-the-ovary
#7
Ahmed El-Balat, Iryna Schmeil, Thomas Karn, Sven Becker, Nicole Sänger, Uwe Holtrich, Ruza Arsenic
Borderline tumors (BOT) of the ovary account for 10% to 20% of ovarian neoplasms. Like ovarian cancer, BOT encompass several different histological subtypes (serous, mucinous, endometrioid, clear cell, transitional cell and mixed) with serous (SBOT) and mucinous (MBOT) the most common. Current hypotheses suggest low-grade serous carcinoma may develop in a stepwise fashion from SBOT whereas the majority of high grade serous carcinomas develop rapidly presumably from inclusion cysts or ovarian surface epithelium...
May 3, 2017: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/28470024/ovarian-endometrioma-superinfected-with-salmonella-case-report-and-review-of-the-literature
#8
Max W Adelman, Jacob H Johnson, Elizabeth L Hohmann, Rajesh T Gandhi
We present the case of a 28-year-old woman with Salmonella serovar Schwarzengrund gastroenteritis acquired during foreign travel. Her case was complicated by superinfection of a pre-existing ovarian endometrioma with a quinolone-resistant organism; the resultant ovarian abscess ultimately required surgical removal for resolution. We review the key features of this case and the previous literature on Salmonella ovarian abscess. This report highlights (1) the potential for metastatic spread of Salmonella to the ovary in women with pre-existing cysts or endometriomas and (2) the increasing worldwide burden of quinolone-resistant Salmonella...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28465851/borderline-clear-cell-adenofibroma-of-the-ovary
#9
Pilaiwan Kleebkaow, Apiwat Aue-Aungkul, Amornrat Temtanakitpaisan, Chumnan Kietpeerakool
Borderline clear cell tumors are extremely rare, and few cases have been reported in the literature. Herein, we present a case of borderline clear cell adenofibroma of the ovary in a 58-year-old woman who presented with a pelvic mass and constipation. Physical examination revealed a 10 cm solid midline pelvic mass. Computed tomography showed an 8 cm heterogeneous enhancing mass attached to the left posterolateral wall of the uterus. The patient's serum CA 125 levels were slightly elevated (80.9 U/ml)...
2017: Case Reports in Pathology
https://www.readbyqxmd.com/read/28450777/rare-locations-of-epidermoid-cyst-case-reports-and-review
#10
Saibaba Mahalakshmi, Sateesha Reddy, T K Ramamurthy, B Shilpa
BACKGROUND: Epidermoid cysts are benign lesions encountered throughout the body. Eighty percent of epidermoid cyst seen in ovaries and testicles, whereas in head and neck region they account for only 1.6-7.0%. 1.6% of epidermoid cysts occur in oral cavity and they account for 0.01% of all the oral cavity cysts. CASE DETAILS: Two case reports of epidermoid cyst has been discussed. One patient reported with well defined swelling in the right lower one third of the face, another one in the upper lip...
November 2016: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/28450253/laparoscopic-management-of-auto-amputated-ovary-in-newborns-a-report-of-two-cases
#11
H N Ladenhauf, M G Brandtner, M A Ardelean, C Schimke, R P Metzger
Intrauterine auto-amputation of the ovary is an extremely rare diagnosis in the pediatric population. Current literature is limited to contradictory recommendations, while a standard management protocol for auto-amputated adnexa secondary to intrauterine ovarian torsion is yet to be established. We report two cases of auto-amputation of the ovary, leading to a free-floating intra-abdominal cyst in the newborn. Laparoscopic management was successful in both cases.
April 24, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28435327/effect-of-menopause-on-hormonal-receptors-in-ampullae-of-the-fallopian-tube-with-a-special-reference-to-the-p53-signature
#12
Rie Urabe, Toru Hachisuga, Taeko Ueda, Toshinori Kawagoe, Tomoko Kurita, Seiji Kagami, Masanori Hisaoka, Yoshihisa Fujino
OBJECTIVES: Age-related changes in the expression of hormonal receptors have not been well examined in the fallopian tube (FT). We herein report the effect of menopause on the hormone receptors in ampullae of the FTs (AFTs), in comparison with cortical inclusion cysts (CICs) of the ovary. METHODS: A total of 84 AFTs and 16 fimbriae of FTs, which were obtained from 26 premenopausal and 58 postmenopausal women; and 27 postmenopausal CICs were immunohistochemically studied for the expression of p53, Ki-67, estrogen receptor-alpha (ER-α), and progesterone receptor A (PRA)...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/28433664/ovaries-of-the-white-worm-enchytraeus-albidus-annelida-clitellata-are-composed-of-16-celled-meroistic-germ-line-cysts
#13
Anna Z Urbisz, Łukasz Chajec, Agnieszka Brąszewska-Zalewska, Janusz Kubrakiewicz, Piotr Świątek
The paired ovaries of E. albidus are like a bunch of grapes and are composed of clearly separated units, syncytial germ cysts (clusters), which are surrounded by a thin layer of somatic cells. Each cyst maintains the connection with the ovary by an extended stalk that is composed of somatic cells. The spatial architecture of the germ-line cysts found in E. albidus is the same as in other clitellate annelids that have been studied to date. As a rule, germ cells are located at the cyst periphery and each has only one ring canal that connects it to the common and centrally located cytoplasmic mass, the cytophore...
April 19, 2017: Developmental Biology
https://www.readbyqxmd.com/read/28432106/prohibitin-induced-obesity-leads-to-anovulation-and-polycystic-ovary-in-mice
#14
Sudharsana Rao Ande, Khanh Hoa Nguyen, Yang Xin Zi Xu, Suresh Mishra
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder and the most common cause of female infertility. However, the etiology of the disease and the mechanisms by which this disorder progress remain unclear. Here we report that a transgenic obese mouse (Mito-Ob) developed by overexpressing prohibitin in adipocytes develops polycystic ovaries. Initially, the female Mito-Ob mice were equally fertile to their wild-type littermates. Mito-Ob mice begin to gain weight after puberty, become significantly obese between 3-6 months of age, and roughly 25% of them become infertile by 9 months of age...
April 21, 2017: Biology Open
https://www.readbyqxmd.com/read/28422330/genetic-relationships-among-female-fertility-disorders-female-fertility-traits-and-productivity-of-holstein-dairy-cows-in-the-early-lactation-period
#15
E Gernand, S König
Fertility health disorders from the early lactation period including retained placenta (REPLA), metritis (MET), corpus luteum persistence (CLP), anoestria/acyclia (AOEAC) and ovarial cysts (OC), as well as overall disease categories (disorders during the postpartal period (DPP), ovary infertility (OINF), overall trait definition "fertility disorders" (FD)), were used to estimate genetic (co)variance components with female fertility and test-day traits. The disease data set comprised 25,142 Holstein cows from parities 1, 2 and 3 resulting in 43,584 lactations...
April 19, 2017: Journal of Animal Breeding and Genetics, Zeitschrift Für Tierzüchtung und Züchtungsbiologie
https://www.readbyqxmd.com/read/28397201/analysis-of-the-factors-determining-the-type-of-surgical-procedure-in-mature-cystic-teratomas
#16
Alev Özer, Hakan Kıran
OBJECTIVES: It was aimed to evaluate which factors determine the surgical procedure selected by surgeons for cases with mature cystic teratoma (MCT). MATERIAL AND METHODS: This study included 50 cases with histopathologically proven MCT between January 2011 and August 2016 at a tertiary reference hospital. Data related to demographic and clinical characteristics were retrieved from medical records. Multivariate logistic regression analysis was conducted to evaluate the independent factors determining the type of surgical procedure to be applied...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28394114/ovarian-teratoma-in-routine-biopsy-material-during-a-five-year-period
#17
Marina Kos, Jasmina Nikić, Tanja Leniček
Teratomas are tumors derived from germ cells, most frequently arising in the gonads. The aim of this study was to determine the number of ovarian teratomas diagnosed in the routine biopsy material at Ljudevit Jurak Clinical Department of Pathology, Sestre milosrdnice University Hospital Center during a 5-year period, as well as their clinical, gross and microscopic characteristics. Teratomas accounted for 48.6% (n=166) of primary ovarian tumors. The patient mean age was 34.74±12.37 years. Difference in the incidence of teratoma between the left and right ovary was not significant; bilateral teratoma was found in 13 patients...
June 2016: Acta Clinica Croatica
https://www.readbyqxmd.com/read/28357094/high-grade-serous-ovarian-cancer-3-years-after-bilateral-salpingectomy-a-case-report
#18
Emi Sato, Kentaro Nakayama, Masako Ishikawa, Kohei Nakamura, Tomoka Ishibashi, Satoru Kyo
Although epithelial ovarian cancer commonly originates from the ovarian surface epithelium and/or ovarian inclusion cysts, it was recently proposed that high-grade serous ovarian cancer (HGSC) develops from the Fallopian tubes. In our department, we encountered a case of HGSC that contradicts the hypothesis of a tubal origin for HGSC. A 51-year-old postmenopausal woman had undergone hysterectomy, left oophorectomy and bilateral salpingectomy for uterine myoma. Three years later, the patient was diagnosed with stage IV ovarian cancer and underwent primary debulking surgery...
February 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28346665/effects-of-ovarian-structures-identified-at-ovsynch%C3%A2-enrolment-disease-history-and-lactation-variables-on-odds-of-pregnancy-to-a-fixed-time-artificial-insemination-after-ovsynch%C3%A2
#19
L Ingenhoff, E Hall, S Ranjbar Ni, J K House
OBJECTIVE: To determine the effects of ovarian structures present at Ovsynch™ enrolment, disease history, lactation variables and times bred on pregnancy per fixed-time artificial insemination (FTAI) following fixed-time insemination after Ovsynch and to determine the relationship between the size of ovarian follicular structures and concurrent presence of a corpus luteum (CL). METHODS: The study was conducted in a 3000-cow Holstein dairy herd. Over a 6-month period, 886 non-pregnant cows were examined by transrectal ultrasound and enrolled into 1132 Ovsynch events...
April 2017: Australian Veterinary Journal
https://www.readbyqxmd.com/read/28296829/ovarian-torsion-in-the-normal-ovary-a-diagnostic-challenge-in-postmenarchal-adolescent-girls-in-the-emergency-department
#20
Erbil Karaman, Burhan Beger, Orkun Çetin, Mehmet Melek, Yasemin Karaman
BACKGROUND Ovarian torsion can be seen in the otherwise-normal ovary and is a challenging issue in the emergency department. The aims were (1) to evaluate and compare the surgically verified ovarian torsion cases in otherwise-normal ovaries and ovaries including a mass or cyst and (2) to investigate whether the normal-appearing ovaries on ultrasound examination affected the diagnosis of ovarian torsion or not. MATERIAL AND METHODS A retrospective cohort study design was used. The medical records of all postmenarchal adolescent girls with surgically verified ovarian torsion treated in a university hospital from 2010 to 2016 were reviewed...
March 15, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
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