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https://www.readbyqxmd.com/read/28808037/separate-mesocortical-and-mesolimbic-pathways-encode-effort-and-reward-learning-signals
#1
Tobias U Hauser, Eran Eldar, Raymond J Dolan
Optimal decision making mandates organisms learn the relevant features of choice options. Likewise, knowing how much effort we should expend can assume paramount importance. A mesolimbic network supports reward learning, but it is unclear whether other choice features, such as effort learning, rely on this same network. Using computational fMRI, we show parallel encoding of effort and reward prediction errors (PEs) within distinct brain regions, with effort PEs expressed in dorsomedial prefrontal cortex and reward PEs in ventral striatum...
August 14, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28807527/does-ct-help-in-predicting-preepiglottic-space-invasion-in-laryngeal-carcinoma
#2
Gülpembe Bozkurt, Özlem Ünsal, İrfan Çelebi, Burak Ayhan, Umman Guliyev, Pınar Akova, Tülay Başak, Berna Uslu Coşkun
OBJECTIVE: Evaluating preepiglottic space involvement in laryngeal cancer by CT may lead misinterpretation. We sought to understand the causes of misinterpretation in evaluating the preepiglottic space by CT and assessed the effects of misinterpretation in treatment plans of patients with laryngeal squamous cell carcinomas. METHODS: Specimen histopathology reports of 102 (99 male, 3 female) patients who underwent total or partial laryngectomy due to supraglottic and/or transglottic laryngeal carcinoma were reviewed...
August 11, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28807470/persistent-pulmonary-embolism-rates-following-total-knee-arthroplasty-even-with-prophylactic-anticoagulants
#3
Mark P Cote, Anthony Chen, Yue Jiang, Vincent Cheng, Jay R Lieberman
BACKGROUND: Symptomatic pulmonary embolism (PE), a significant and life-threatening complication following total knee arthroplasty (TKA), has been described as a "never event." Despite a number of advancements in care, PE continues to occur following TKA. This study evaluates symptomatic PE rates over time in TKA patients enrolled in multicenter randomized clinical trials assessing the efficacy of venous thromboembolism prophylaxis regimens. METHODS: The MEDLINE and Cochrane Central Register of Controlled Trials were searched to identify clinical trials assessing prophylactic anticoagulation in patients undergoing TKA between January 1995 and December 2016...
July 5, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28806696/dft-approach-to-benzylthio-acetic-acid-conformational-search-molecular-monomer-and-dimer-structure-vibrational-spectroscopy-and-some-electronic-properties
#4
Justyna Sienkiewicz-Gromiuk
The DFT studies were carried out with the B3LYP method utilizing the 6-31G and 6-311++G(d,p) basis sets depending on whether the aim of calculations was to gain the geometry at equilibrium, or to calculate the optimized molecular structure of (benzylthio)acetic acid (Hbta) in the forms of monomer and dimer. The minimum conformational energy search was followed by the potential energy surface (PES) scan of all rotary bonds existing in the acid molecule. The optimized geometrical monomeric and dimeric structures of the title compound were compared with the experimental structural data in the solid state...
July 29, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28805304/a-systematic-review-and-meta-analysis-of-mental-health-service-use-in-people-who-report-psychotic-experiences
#5
REVIEW
Vishal Bhavsar, Philip McGuire, James MacCabe, Dominic Oliver, Paolo Fusar-Poli
BACKGROUND: Self-reported psychotic experiences (PEs) are associated with psychopathology of all kinds, not just psychoses. However, systematic reviews on the relevance of this for health services are unavailable. Furthermore, whether association with service use is confounded by other psychopathology is unknown, and is relevant to prevention and treatment. OBJECTIVES: Literature examining associations between PEs and service use was systematically reviewed. Study quality and the direction and extent of any associations were assessed, and meta-analysis conducted...
August 14, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/28805229/a-ground-state-potential-energy-surface-for-hono-based-on-a-neural-network-with-exponential-fitting-functions
#6
Ekadashi Pradhan, Alex Brown
The minimum energy structures, i.e., trans-HONO, cis-HONO, HNO2, and OH + NO, as well as the corresponding transition states, i.e., TStrans↔cis, TS1,2H-shift, and TS1,3H-shift, on the ground state potential energy surface (PES) of HONO have been characterized at the CCSD(T)-F12/cc-pVTZ-F12 level of theory. Using the same level of theory, a six-dimensional (6D) PES, encompassing the trans- and cis-isomers as well as the associated transition state, is fit in a sum-of-products form using neural network exponential fitting functions...
August 14, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28804801/pancreatic-enzyme-supplementation-after-gastrectomy-for-gastric-cancer-a-randomized-controlled-trial
#7
Marco Catarci, Manuele Berlanda, Giovanni Battista Grassi, Francesco Masedu, Stefano Guadagni
BACKGROUND: Gastrectomy for gastric cancer is a significant cause of secondary exocrine pancreatic insufficiency. Pancreatic enzyme replacement therapy may influence nutritional status and quality of life after gastrectomy, but the pertinent clinical research to date remains controversial. A randomized controlled trial to test this hypothesis was carried out. METHODS: After gastrectomy, 43 patients with gastric cancer were randomly assigned to a normal diet (Normal-d; n = 21) or to a pancreatic enzyme supplementation diet (PES-d; n = 22) and were followed up during a 12-month period, assessing nutritional status and quality of life through body mass index (BMI), instant nutritional assessment (INA) class status, serum pre-albumin (SPA) values, and GastroiIntestinal Quality of Life Index (GIQLI)...
August 14, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/28804760/autopsy-case-of-the-c12orf65-mutation-in-a-patient-with-signs-of-mitochondrial-dysfunction
#8
Hideaki Nishihara, Masatoshi Omoto, Masaki Takao, Yujiro Higuchi, Michiaki Koga, Motoharu Kawai, Hiroo Kawano, Eiji Ikeda, Hiroshi Takashima, Takashi Kanda
OBJECTIVE: To describe the autopsy case of a patient with a homozygous 2-base deletion, c171_172delGA (p.N58fs), in the C12orf65 gene. METHODS: We described the clinical history, neuroimaging data, neuropathology, and genetic analysis of the patients with C12orf65 mutations. RESULTS: The patient was a Japanese woman with a history of delayed psychomotor development, primary amenorrhea, and gait disturbance in her 20s. She was hospitalized because of respiratory failure at the age of 60...
August 2017: Neurology. Genetics
https://www.readbyqxmd.com/read/28804467/learning-about-expectation-violation-from-prediction-error-paradigms-a-meta-analysis-on-brain-processes-following-a-prediction-error
#9
Lisa D'Astolfo, Winfried Rief
Modifying patients' expectations by exposing them to expectation violation situations (thus maximizing the difference between the expected and the actual situational outcome) is proposed to be a crucial mechanism for therapeutic success for a variety of different mental disorders. However, clinical observations suggest that patients often maintain their expectations regardless of experiences contradicting their expectations. It remains unclear which information processing mechanisms lead to modification or persistence of patients' expectations...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28802444/identifying-the-critical-physical-demanding-tasks-of-paramedic-work-towards-the-development-of-a-physical-employment-standard
#10
Steven L Fischer, Kathryn E Sinden, Renee S MacPhee
Public safety related occupations including police, fire and military commonly apply physical employment standard (PES) to facilitate job matching, an approach to evaluate if candidates demonstrate acceptable physical capabilities as required to perform the job safely and effectively. In Canada, paramedics remain as one of the few public safety occupations without an evidence-based, validated PES. The purpose of this study was to document and describe the physical demands of paramedic work and to identify the most physically demanding tasks...
November 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28802173/fungicidal-activity-of-copper-sputtered-flexible-surfaces-under-dark-and-actinic-light-against-azole-resistant-candida-albicans-and-candida-glabrata
#11
Myriam K S Ballo, Sami Rtimi, John Kiwi, César Pulgarin, José M Entenza, Alain Bizzini
Candida spp. are able to survive on hospital surfaces and causes healthcare-associated infections (HCAIs). Since surface cleaning and disinfecting interventions are not totally effective to eliminate Candida spp., new approaches should be devised. Copper (Cu) has widely recognized antifungal activity and the use of Cu-sputtered surfaces has recently been proposed to curb the spread of HCAIs. Moreover, the activity of Cu under the action of actinic light remains underexplored. We investigated the antifungal activity of Cu-sputtered polyester surfaces (Cu-PES) against azole-resistant Candida albicans and Candida glabrata under dark and low intensity visible light irradiation (4...
July 29, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28800431/anharmonic-vibrational-analysis-of-s-trans-and-s-cis-conformers-of-acryloyl-fluoride-using-numerical-analytic-van-vleck-operator-perturbation-theory
#12
Sergey V Krasnoshchekov, Norman C Craig, Lidiya A Koroleva, Nikolay F Stepanov
A new gas-phase infrared (IR) spectrum of acryloyl fluoride (ACRF, CH2CHCFO) with a resolution of 0.1cm(-1) in the range 4000-450cm(-1) was measured. Theoretical ab initio molecular structures, full quartic potential energy surfaces (PES), and cubic surfaces of dipole moments and polarizability tensor components (electro-optical properties, EOP) of the s-trans and s-cis conformers of the ACRF were calculated by the second-order Møller-Plesset electronic perturbation theory with a correlation consistent Dunning triple-ζ basis set...
August 1, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28800209/using-local-clinical-educators-and-shared-resources-to-deliver-simulation-training-activities-across-rural-and-remote-south-australia-and-south-west-victoria-a-distributed-collaborative-model
#13
Stacey C Masters, Sandi Elliott, Sarah Boyd, James A Dunbar
PROBLEM: There is a lack of access to simulation-based education (SBE) for professional entry students (PES) and health professionals at rural and remote locations. DESIGN: A descriptive study. SETTING: Health and education facilities in regional South Australia and south-west Victoria. KEY MEASURES FOR IMPROVEMENT: Number of training recipients who participated in SBE; geographical distribution and locations where SBE was delivered; number of rural clinical educators providing SBE...
August 11, 2017: Australian Journal of Rural Health
https://www.readbyqxmd.com/read/28799340/theoretical-study-of-the-buffer-gas-cooling-and-trapping-of-crh-x-6-%C3%AE-by-3-he-atoms
#14
Jacek Kłos, Michał Hapka, Grzegorz Chałasiński, Philippe Halvick, Thierry Stoecklin
We present a theoretical study of the Zeeman relaxation of the magnetically trappable lowest field seeking state of CrH(X(6)Σ(+)) in collisions with (3)He. A two dimensional potential energy surface (PES) was calculated with the partially spin-restricted coupled cluster singles, doubles, and non-iterative triples [RCCSD(T)] method. The global minimum was found for the collinear He⋯Cr-H geometry with the well depth of 1143.84 cm(-1) at Re = 4.15 a0. Since the RCCSD(T) calculations revealed a multireference character in the region of the global minimum, we performed additional calculations with the internally contracted multireference configuration interaction with the Davidson correction (ic-MRCISD+Q) method...
December 7, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28797561/self-reported-psychosis-like-experiences-in-patients-with-mood-disorders
#15
I Baryshnikov, J Suvisaari, K Aaltonen, M Koivisto, T Melartin, P Näätänen, K Suominen, B Karpov, M Heikkinen, J Oksanen, T Paunio, G Joffe, E Isometsä
BACKGROUND: Self-reported psychosis-like experiences (PEs) may be common in patients with mood disorders, but their clinical correlates are not well known. We investigated their prevalence and relationships with self-reported symptoms of depression, mania, anxiety, borderline (BPD) and schizotypal (SPD) personality disorders among psychiatric patients with mood disorders. METHODS: The Community Assessment of Psychic Experiences (CAPE-42), Mood Disorder Questionnaire (MDQ), McLean Screening Instrument (MSI), The Beck Depressive Inventory (BDI), Overall Anxiety Severity and Impairment Scale (OASIS) and Schizotypal Personality Questionnaire-Brief form (SPQ-B) were filled in by patients with mood disorders (n=282) from specialized care...
February 3, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28796491/excellent-biofouling-alleviation-of-thermoexfoliated-vermiculite-blended-polyethersulfone-ultrafiltration-membrane
#16
Yasin Orooji, Feng Liang, Amir Razmjou, Sha Li, Mohammad Reza Mofid, Quan Liu, Kecheng Guan, ZhengKun Liu, Wanqin Jin
Flux and antifouling properties of mixed matrix membranes (MMM) are yet to attain satisfactory status. The aim of this study is to find a method for mitigating the biofouling of polyethersulfone (PES) ultrafiltration membranes via blending of thermoexfoliated vermiculite (VMT). Flow cytometry analysis shows that the behaviors of Bacillus subtilis 168 as a gram-positive bacterium and Escherichia coli DH5 alpha as a gram-negative bacterium were different. Hence, cell property is a suspected contributory factor in biofilm formation...
August 10, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28792270/enhancement-of-biochemical-and-nutritional-contents-of-some-cultivated-seaweeds-under-laboratory-conditions
#17
Mona M Ismail, Mostafa El-Sheekh
Six species of macroalgae belonging to the Chlorophyta, Phaeophyta, and Rhodophyta divisions were cultivated in a closed system with Guillard's f/2, Walne's, Provasoli Enriched Seawater (PES) medium, and seawater (control) for 6 weeks. The growth rate and parameters of the tested seaweeds showed that all used media enhanced the growth rate and chemical content as compared with other seaweeds cultivated in seawater without addition of any nutrients. There are significant differences in the effect of the used media on the seaweed composition at p = ...
August 9, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28780516/diagnosis-of-endocrine-disease-primary-empty-sella-a-comprehensive-review
#18
Sabrina Chiloiro, Antonella Giampietro, Antonio Bianchi, Tommaso Tartaglione, Antonio Capobianco, Carmelo Anile, Laura De Marinis
Primary empty sella (PES) is characterized by the herniation of the subarachnoid space within the sella, which is often associated with variable degree of flattening of the pituitary gland in patients without previous pituitary pathologies. PES pathogenetic mechanism are not well known but seem due to a sellar diaphragm incompetence, associated to the occurrence of upper sellar or pituitary factors, as intracranial hypertension and change of pituitary volume. As PES represents in majority of cases a neuroradiological findings, without any clinical implication, the occurrence of endocrine, neurological and opthalmological symptoms, due to the above describes anatomical alteration, delineates the so called PES syndrome...
August 5, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28779806/did-failure-occur-because-of-medial-column-instability-that-was-not-recognized-or-did-it-develop-after-surgery
#19
REVIEW
Anish R Kadakia, Armen S Kelikian, Mauricio Barbosa, Milap S Patel
Medial column instability is a primary deforming force in the setting of pes planovalgus deformity. Consideration for medial column stabilization only after correction of the hindfoot deformity may result in creating a rigid hindfoot, compromising clinical outcomes. Careful analysis of the lateral radiograph to determine whether the deformity is secondary to the medial column or true peritalar subluxation may allow superior outcomes. Iatrogenic creation of an excessively rigid medial column may lead to significant instability of the remaining joints in the short term and arthrosis in the long term...
September 2017: Foot and Ankle Clinics
https://www.readbyqxmd.com/read/28778007/application-of-saponin-biosurfactant-and-its-recovery-in-the-meuf-process-for-removal-of-methyl-violet-from-wastewater
#20
Kulbhushan Samal, Chandan Das, Kaustubha Mohanty
The potential of saponin, a biosurfactant, in the micellar enhanced ultrafiltration (MEUF) process was tested systematically for removal of methyl violet from wastewater. For this, the aqueous extract of reetha (Sapindus mukorossi) pericarp which contains saponin was used as the biosurfactant. First, the micellar solubilization of methyl violet in saponin micelles was investigated in terms of molar solubilization power (SP) of saponin. It was observed that the adsorption of methyl violet on the agglomerates of saponin micelles was mainly responsible for the enhanced solubilization...
August 1, 2017: Journal of Environmental Management
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