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https://www.readbyqxmd.com/read/29767339/simultaneous-decolorization-and-deproteinization-of-%C3%AE-%C3%AF-dodecanedioic-acid-fermentation-broth-by-integrated-ultrafiltration-and-adsorption-treatments
#1
Weifeng Cao, Yujue Wang, Jianquan Luo, Junxiang Yin, Yinhua Wan
α,ω-Dicarboxylic acids (DC) are versatile chemical intermediates with different chain length. For biosynthesis of DC, to obtain the highly pure product via crystallization, it is required to remove pigments and proteins in fermentation broth. However, a trade-off between decolorization/deproteinization ratio and DC recovery during the purification process was found, which impeded DC production by fermentation. When ultrafiltration (UF) was applied to treat α,ω-dodecanedioic acid (DC12 ) broth, 93.4% of DC12 recovery, 80...
May 16, 2018: Bioprocess and Biosystems Engineering
https://www.readbyqxmd.com/read/29766644/evaluation-of-the-influence-of-implant-placement-timing-on-the-esthetic-outcomes-of-single-tooth-implant-treatment-in-the-anterior-maxilla-a-retrospective-study
#2
Himanshu Arora, Saso Ivanovski
OBJECTIVES: The purpose of this retrospective study was to investigate the influence of implant placement timing on the esthetic outcomes for single implants in the anterior maxilla. MATERIALS AND METHODS: One hundred and ten patients (48 males; 62 females) who received a single-tooth implant after extraction either immediately (Type 1); after 4-8 weeks (Type 2); after 8-16 weeks (Type 3); or more than 16 weeks (Type 4) were evaluated in terms of esthetic outcomes after a mean post-placement interval of 26...
May 15, 2018: Journal of Esthetic and Restorative Dentistry
https://www.readbyqxmd.com/read/29765423/comparison-of-teratoma-formation-between-embryonic-stem-cells-and-parthenogenetic-embryonic-stem-cells-by-molecular-imaging
#3
Hongyan Tao, Xiaoniao Chen, Anbang Wei, Xianghe Song, Weiqiang Wang, Lu Liang, Qinjun Zhao, Zhibo Han, Zhongchao Han, Xiaojing Wang, Zongjin Li
With their properties of self-renewal and differentiation, embryonic stem (ES) cells hold great promises for regenerative therapy. However, teratoma formation and ethical concerns of ES cells may restrict their potential clinical applications. Currently, parthenogenetic embryonic stem (pES) cells have attracted the interest of researchers for its self-renewing and pluripotent differentiation while eliciting less ethic concerns. In this study, we established a model with ES and pES cells both stably transfected with a double-fusion reporter gene containing renilla luciferase (Rluc) and red fluorescent protein (RFP) to analyze the mechanisms of teratoma formation...
2018: Stem Cells International
https://www.readbyqxmd.com/read/29764478/improved-symptomatic-functional-and-fluoroscopic-outcomes-following-serial-series-of-three-double-balloon-dilation-for-cricopharyngeus-muscle-dysfunction
#4
Derrick R Randall, Lisa M Evangelista, Maggie A Kuhn, Peter C Belafsky
BACKGROUND: Cricopharyngeus muscle dysfunction (CPMD) is a common cause of dysphagia. We employ a progressive series of three double-balloon dilations separated by 4-6 weeks between procedures as a primary treatment option. The purpose of this study was to evaluate subjective, functional and objective improvement in swallowing after three serial dilations for CPMD. METHODS: We retrospectively evaluated patients between June 1, 2014, and June 30, 2016, who underwent a series of three double-balloon dilations for CPMD...
May 15, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29763629/ventricular-pro-arrhythmic-phenotype-arrhythmic-substrate-ageing-and-mitochondrial-dysfunction-in-peroxisome-proliferator-activated-receptor-%C3%AE-coactivator-1%C3%AE-deficient-pgc-1%C3%AE-murine-hearts
#5
Shiraz Ahmad, Haseeb Valli, Karan R Chadda, James Cranley, Kamalan Jeevaratnam, Christopher L-H Huang
INTRODUCTION: Ageing and age-related bioenergetic conditions including obesity, diabetes mellitus and heart failure constitute clinical ventricular arrhythmic risk factors. MATERIALS AND METHODS: Pro-arrhythmic properties in electrocardiographic and intracellular recordings were compared in young and aged, peroxisome proliferator-activated receptor-γ coactivator-1β knockout (Pgc-1β-/- ) and wild type (WT), Langendorff-perfused murine hearts, during regular and programmed stimulation (PES), comparing results by two-way ANOVA...
May 12, 2018: Mechanisms of Ageing and Development
https://www.readbyqxmd.com/read/29759229/evaluation-of-polar-organic-chemical-integrative-and-hollow-fibre-samplers-for-the-determination-of-a-wide-variety-of-organic-polar-compounds-in-seawater
#6
Leire Mijangos, Haizea Ziarrusta, Ailette Prieto, Oihane Zugazua, Olatz Zuloaga, Maitane Olivares, Aresatz Usobiaga, Albrecht Paschke, Nestor Etxebarria
The calibration of two passive samplers for the determination of 20 emerging organic compounds in seawater is described in this work: i) a new version of polar organic chemical integrative sampler (POCIS) containing 100 mg of mixed-mode anion exchanger (Strata X-AW) and 100 mg of polymeric HLB (Plexa) sorbent materials and using a highly porous Nylon membrane (30-μm pore size) and ii) polyethersulfone (PES) hollow fibre. Among the studied contaminants, herbicides, hormones, life style products (stimulants and artificial sweeteners), industrial chemicals (corrosion inhibitor and fluorinated compounds), personal care products and several pharmaceuticals were included...
August 1, 2018: Talanta
https://www.readbyqxmd.com/read/29759125/common-soft-tissue-musculoskeletal-pain-disorders
#7
REVIEW
Matthew J Hubbard, Bernard A Hildebrand, Monica M Battafarano, Daniel F Battafarano
Soft tissue musculoskeletal pain disorders are common in the primary care setting. Early recognition and diagnosis of these syndromes minimizes patient pain and disability. This article gives a brief overview of the most common soft tissue musculoskeletal pain syndromes. The authors used a regional approach to organize the material, as providers will encounter these syndromes with complaints of pain referring to an anatomic location. The covered disorders include myofascial pain syndrome, rotator cuff tendinopathy, bicipital tendinopathy, subacromial bursitis, olecranon bursitis, epicondylitis, De Quervain disease, trigger finger, trochanteric bursitis, knee bursitis, pes anserine bursitis, Baker cyst, plantar fasciitis, and Achilles tendinopathy...
June 2018: Primary Care
https://www.readbyqxmd.com/read/29757648/potential-energy-surface-for-large-barrierless-reaction-systems-application-to-the-kinetic-calculations-of-the-dissociation-of-alkanes-and-the-reverse-recombination-reactions
#8
Qian Yao, Xiao-Mei Cao, Wen-Gang Zong, Xiao-Hui Sun, Ze-Rong Li, Xiang-Yuan Li
The isodesmic reaction method is applied to calculate the potential energy surface (PES) along the reaction coordinates and the rate constants of the barrierless reactions for unimolecular dissociation reactions of alkanes to form two alkyl radicals and their reverse recombination reactions. The reaction class is divided into 10 subclasses depending upon the type of carbon atoms in the reaction centers. A correction scheme based on isodesmic reaction theory is proposed to correct the PESs at UB3LYP/6-31+G(d,p) level...
May 14, 2018: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29755110/endostatin-gene-therapy-delivered-by-attenuated-salmonella-typhimurium-in-murine-tumor-models
#9
Kang Liang, Qing Liu, Pei Li, Yue Han, Xiaoping Bian, Yibo Tang, Qingke Kong
Salmonella typhimurium (hereafter S. typhimurium), as Gram-negative facultative anaerobic bacteria, are good candidates for cancer therapy and delivering therapeutic antitumor agents. However, it is necessary to reduce the virulence of such bacteria and enhance their tumor-targeting ability, and their immunostimulatory ability to induce tumor cell apoptosis. In this study, we constructed a S. typhimurium mutant named S634 harboring aroA mutation and additional mutations involved in modifications of lipid A...
May 14, 2018: Cancer Gene Therapy
https://www.readbyqxmd.com/read/29753998/use-of-high-speed-stereo-radiography-to-assess-the-foot-orthoses-effectiveness-in-controlling-midfoot-posture-during-walking-a-pilot-study
#10
Erin M Mannen, Stuart J Currie, Elizabeth C Bachman, Amira Otmane, Bradley S Davidson, Kevin B Shelburne, Thomas G McPoil
BACKGROUND: The intent of this pilot study was to determine the feasibility of using high-speed stereo radiography (HSSR) to assess the effectiveness of footwear and foot orthoses in controlling the change in the position of the midfoot during walking in individuals with a flexible pes planus foot type. METHODS: Four individuals (1 female; 3 male) with a mean age of 25 years (range 22-29) and a bilateral flexible pes planus foot type participated in the study. The HSSR system was used to measure 3-dimensional changes in the longitudinal arch angle (LAA) with each participant walking barefoot, shoe only and shoes with orthoses...
January 31, 2018: Foot
https://www.readbyqxmd.com/read/29751667/study-on-the-characteristics-of-walnut-shell-co-pes-co-pa-powder-produced-by-selective-laser-sintering
#11
Yueqiang Yu, Yanling Guo, Ting Jiang, Jian Li, Kaiyi Jiang, Hui Zhang, Yu Zhuang
Agricultural and forestry wastes are used as materials for selective laser sintering (SLS) to alleviate resource shortage, reduce the pollution of the environment, lower the cost of materials, and improve the accuracy of parts produced by SLS. However, the mechanical properties of wood⁻plastic parts are poor, and thus they cannot be applied widely. In order to improve the mechanical properties of wood⁻plastic parts, a new type of walnut shell polymer composite (WSPC) was prepared by a polymer mixing method and was used to produce parts via SLS...
May 11, 2018: Materials
https://www.readbyqxmd.com/read/29750431/a-serial-three-and-nine-year-optical-coherence-tomography-evaluation-of-neoatherosclerosis-progression-after-sirolimus-and-paclitaxel-eluting-stents-implantation
#12
Mariusz Tomaniak, Janusz Kochman, Łukasz Kołtowski, Arkadiusz Pietrasik, Adam Rdzanek, Jacek Jąkała, Klaudia Proniewska, Krzysztof Malinowski, Dorota Ochijewicz, Krzysztof J Filipiak, Salvatore Brugaletta, Grzegorz Opolski
BACKGROUND: Early-generation drug-eluting stents (DES) have been shown to accelerate neoatherogenesis. Limited optical coherence tomography (OCT) data on the very long-term neoatherosclerosis progression after DES implantation are available. AIM: The aim of this study was a serial OCT evaluation of neoatherosclerosis at 3 and 9 years after implantation of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES). METHODS: Consecutive patients undergoing elective PCI with SES (Cypher, Cordis) or PES (Taxus, Boston Scientific) were included in this single-centre, longitudinal study...
May 11, 2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29750187/revealing-pathways-from-payments-for-ecosystem-services-to-socioeconomic-outcomes
#13
Hongbo Yang, Wu Yang, Jindong Zhang, Thomas Connor, Jianguo Liu
Payments for ecosystem services (PES) programs have been widely implemented as a promising tool to conserve ecosystems while facilitating socioeconomic development. However, the underlying pathways (or processes) through which PES programs affect socioeconomic outcomes remain elusive, and existing literature provides little guidance to quantify them. By integrating linkages among PES programs, livelihood activities, and socioeconomic outcomes, we develop a framework to reveal pathways from PES programs to socioeconomic outcomes...
March 2018: Science Advances
https://www.readbyqxmd.com/read/29747250/-rare-primary-proximal-epithelioid-sarcoma-in-skull-base-clinical-analysis-of-four-cases
#14
Z J Duan, K Yao, Y M Qu, M Ren, Y L Zhang, X L Qi
Objective: To report the clinical and pathological features of primary proximal epithelioid sarcoma (PES) in skull base. Methods: The clinical and pathological features of four cases of PES in skull base from Sanbo Brain Institute of Capital Medical University and Kunming Sanbo Brain Institute were analysed retrospectively. Results: Three cases was female, and one male, the age ranged from 46 to 52 years.All cases occurred in skull base, and sellar region was the main site of involvement.Under the microscope, the tumor cells characterized by epithelioid cell changes, with or without rhabdoid tumor cells...
April 7, 2018: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29746423/total-pharyngo-esophageal-stenosis-a-new-surgical-procedure-using-modified-retrograde-transillumination-approach
#15
Jerome R Lechien, Giovanni Dapri, Sven Saussez
We performed a modified combined anterograde-retrograde dilatation in a 60-year-old woman with complete pharyngo-esophageal stricture (PES). With a large endoscopic view from the upper (laryngoscope) and lower (pediatric gastroscope introduced via gastrostomy tube) parts of the PES, the approach consisted of a retrograde puncture of the complete PES by transillumination to take the guide coming from the pediatric endoscope. The guide was pulled through the mouth and the PES dilatation was made using successive boogies of various diameters through the guide...
May 9, 2018: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/29744938/accurate-determination-of-energy-requirements-in-hospitalised-patients-with-parenteral-nutrition
#16
G Quiroz-Olguín, I Medina-Vera, A E Serralde-Zúñiga, A Gulias-Herrero, A I Sánchez-Rosales, M Guevara-Cruz
BACKGROUND: The prescription of parenteral nutrition (PN) in hospitalised patients requires an estimation of the energy requirements. Most studies employing prediction equations (PEs) to estimate energy requirements have focused on critically ill patients. The present study aimed to evaluate several PEs of the resting energy expenditure (REE) to identify the most accurate equation for estimating the REE required for PN. METHODS: This cross-sectional and descriptive study included patients hospitalised with medical or surgical diagnoses, making them candidates for PN...
May 9, 2018: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/29744486/thermodynamically-accessible-titanium-clusters-ti-n-n-2-32
#17
Tomas Lazauskas, Alexey A Sokol, John Buckeridge, C Richard A Catlow, Susanne G E T Escher, Matthew R Farrow, David Mora-Fonz, Volker W Blum, Tshegofatso M Phaahla, Hasani R Chauke, Phuti E Ngoepe, Scott M Woodley
We have performed a genetic algorithm search on the tight-binding interatomic potential energy surface (PES) for small TiN (N = 2-32) clusters. The low energy candidate clusters were further refined using density functional theory (DFT) calculations with the PBEsol exchange-correlation functional and evaluated with the PBEsol0 hybrid functional. The resulting clusters were analysed in terms of their structural features, growth mechanism and surface area. The results suggest a growth mechanism that is based on forming coordination centres by interpenetrating icosahedra, icositetrahedra and Frank-Kasper polyhedra...
May 10, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29742489/renal-denervation-effects-on-myocardial-fibrosis-and-ventricular-arrhythmias-in-rats-with-ischemic-cardiomyopathy
#18
Bin Zhang, Xiaorong Li, Chu Chen, Wanying Jiang, Dasheng Lu, Qian Liu, Kai Wang, Yuhao Yan, Zhixin Jiang, Jie Geng, Hai Xu, Qijun Shan
BACKGROUND/AIMS: To investigate the impact of renal denervation (RDN) on myocardial fibrosis and ventricular arrhythmias (VAs) in rats with ischemic cardiomyopathy. METHODS: An ischemic cardiomyopathy model was reproduced with myocardial infarction (MI) in adult Sprague-Dawley male rats. The RDN/Sham-RDN procedure was performed at 2 weeks after MI. Sham-MI and sham-RDN rats served as the control group. At 4 weeks after RDN, programmed electrical stimulation (PES) was used to induce VAs, including ventricular tachycardia and ventricular fibrillation, in all 3 groups (MI+RDN, MI, and control groups)...
May 5, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29741369/advanced-anti-fouling-membranes-for-osmotic-power-generation-from-wastewater-via-pressure-retarded-osmosis-pro
#19
Gang Han, Jiang Tao Liu, Kangjia Lu, Tai-Shung Chung
A facile and versatile approach was demonstrated for the fabrication of low-fouling pressure retarded osmosis (PRO) membranes for osmotic power generation from highly polluted wastewater. A water-soluble zwitterionic random copolymer with superior hydrophilicity and unique chemistry was molecularly designed and synthesized via a single-step free-radical polymerization between 2-methacryloyloxyethyl phosphorylcholine (MPC) and 2-aminoethyl methacrylate hydrochloride (AEMA). The P[MPC-co-AEMA] copolymer was then chemically grafted onto the surface of PES&Torlon hollow fibers via amino groups coupling of poly(AEMA) with the polyimide structures of Torlon, leaving the zwitterions of poly(MPC) in the feed solution...
May 9, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29739763/iatrogenic-immunosuppression-may-favour-alternaria-skin-lesion-flares
#20
Rosanna Satta, Maria Pina Dore, Giovanni Mario Pes, Gabriele Biondi
Alternaria spp may cause opportunistic mycoses in the skin after cutaneous inoculation or through blood dissemination in immune-suppressed patients. Here, we describe a case of cutaneous infection with Alternaria spp in a 62-year-old man, presenting with multifocal papules and erythematous nodules involving distal limbs bilaterally. The absence of inflammatory bowel disease was confirmed by a gastroenterologist. The patient was under treatment for uveitis of unknown origin with immunosuppressive doses of cyclosporin and prednisolone for approximately 3 months...
May 8, 2018: BMJ Case Reports
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