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pseudoexfoliation And hearing loss

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https://www.readbyqxmd.com/read/26997634/biological-effect-of-loxl1-coding-variants-associated-with-pseudoexfoliation-syndrome
#1
Shiwani Sharma, Sarah Martin, Matthew J Sykes, Alpana Dave, Alex W Hewitt, Kathryn P Burdon, Maurizio Ronci, Nicolas H Voelcker, Jamie E Craig
Pseudoexfoliation (PEX) syndrome is a systemic disease involving the extracellular matrix. It increases the risk of glaucoma, an irreversible cause of blindness, and susceptibility to heart disease, stroke and hearing loss. Single nucleotide polymorphisms (SNPs) in the LOXL1 (Lysyl oxidase-like 1) gene are the major known genetic risk factor for PEX syndrome. Two coding SNPs, rs1048861 (G > T; Arg141Leu) and rs3825942 (G > A; Gly153Asp), in the LOXL1 gene are strongly associated with the disease risk in multiple populations worldwide...
May 2016: Experimental Eye Research
https://www.readbyqxmd.com/read/24864196/association-between-ocular-pseudoexfoliation-and-sensorineural-hearing-loss
#2
Nandini Vijaya Singham, Mimiwati Zahari, Mohammadreza Peyman, Narayanan Prepageran, Visvaraja Subrayan
Background. Our study aimed to investigate an association between ocular pseudoexfoliation (PXF) and sensorineural hearing loss (SNHL) and to compare them with age and sex matched controls without pseudoexfoliation. Method. This was a case-control study of 123 patients which included 68 cases with PXF (at least one eye) and 55 controls without pseudoexfoliation. Pure-tone audiometry (PTA) was done for these patients at sound frequencies taken as important for speech comprehension, that is, 250 Hertz (Hz), 500 Hz, 1000 Hz, and 2000 Hz...
2014: Journal of Ophthalmology
https://www.readbyqxmd.com/read/24303375/pseudoexfoliation-syndrome-and-sensorineural-hearing-loss
#3
Ramin Zojaji, Ali Alesheykh, Mohammad Reza Sedaghat, Kiamarz Navia, Morteza Mazloom Farsi Baf, Masoud Khaki, Aliasghar Raouf
INTRODUCTION: Pseudoexfoliation syndrome (PXS) occurs due to the deposition of extracellular fibrillar materials on the anterior chamber of the eye. This syndrome has been considered to be part of a systemic disease with the potential involvement of the inner ear called sensoroneural hearing loss (SNHL). In this study, we aimed on evaluating SNHL within PXS patients in Iran to compare them with other international reports. MATERIALS AND METHODS: In total, 33 patients with PXS and 33 age and sex matched controls were enrolled prospectively in a case-control study...
2011: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/22773995/sensory-neural-hearing-loss-in-pseudoexfoliation-syndrome
#4
Vafa Samarai, Reza Samarei, Negar Haghighi, Elnaz Jalili
AIM: To evaluate relationship between ocular pseudoexfoliation syndrome(PXF) and sensory-neural hearing loss (SNHL). METHODS: This prospective case-control study was designed on patients who referred to a general ophthalmic clinic at Imam Khomeini Medical Center, Urmia, Iran (March 2010 through November 2010). On routine ophthalmic examination, patients diagnosed with ocular PXF were referred to the ENT department and, selected cases (after evaluating inclusion and exclusion criteria) were referred to Audiometric Department...
2012: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/21707986/prevalence-of-pseudoexfoliation-syndrome-and-pseudoexfoliation-glaucoma-in-upper-egypt
#5
Tarek A Shazly, Abdelsattar N Farrag, Asmaa Kamel, Ashraf K Al-Hussaini
BACKGROUND: Pseudoexfoliation (PXF) is a recognized risk factor for developing cataract, glaucoma and lens dislocation. PXF is also associated with increased risk of complications during cataract surgery due to poor mydriasis and zonular weakness. The aim of this study is to report the prevalence of pseudoexfoliation among Upper Egyptians attending the ophthalmology clinic of Assiut University Hospital. METHODOLOGY: A retrospective, chart review study conducted in the period from February 2002 to August 2009...
2011: BMC Ophthalmology
https://www.readbyqxmd.com/read/21063289/is-pseudoexfoliation-associated-with-sensorineural-hearing-loss
#6
Faruk Ozturk, Emin Kurt, Umit U Inan, Sefa Derekoy, Sitki S Ermis, Ali Asagidag
OBJECTIVE: To determine the possible relation between pseudoexfoliation (PSX) and sensorineural hearing loss. METHODS: This study was carried out in Afyon Kocatepe University, Afyon, Turkey between July 2002 and June 2005. Sixty-three patients who were found to have ocular PSX on routine biomicroscopic examination, and 38 age-matched control subjects were evaluated for evidence of audiometric abnormality. The sum of pure-tone hearing threshold measured at 250-2000 Hz, 2000-6000 Hz, and 250-6000 Hz in each ear was compared with controls for the same frequencies...
January 2008: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/19857190/-function-of-outer-hair-cells-in-patients-with-pseudoexfoliation
#7
Seyra Erbek, Selim S Erbek, Aylin Karalezli, Mehmet Borazan, Levent N Ozlüoğlu
OBJECTIVES: In this study, we aimed to assess whether outer hair cell function in patients with pseudoexfoliation syndrome (PES) was affected or not. PATIENTS AND METHODS: Thirty-two patients (21 males, 11 females; mean age 69.8+/-9.3 years; range 49 to 86 years) with the diagnosis of PES and 23 healthy subjects (12 males, 11 females; mean age 65.3+/-9.1 year; range 51 to 79 years) as control group were included in the study. All of the subjects were evaluated with pure tone audiometry, tympanometry, and transient otoacoustic emission tests...
May 2009: Kulak Burun Boğaz Ihtisas Dergisi: KBB, Journal of Ear, Nose, and Throat
https://www.readbyqxmd.com/read/19756678/the-evaluation-of-vestibular-functions-in-patients-with-pseudoexfoliation-syndrome
#8
Burak Turgut, Hayrettin Cengiz Alpay, Mehmet Kaan Kaya, Muzaffer Oger, Ulku Celiker, Sinasi Yalcin
The main objective of the study is to evaluate vestibular system of the inner ear with postural tests in the patients with pseudoexfoliation syndrome (PEX). It is clinical case-control study. The study group included 34 patients with PEX and 40 controls without PEX. The patients and controls underwent complete ophthalmic and otorhinolaryngologic examinations. Vestibular functions were done by Fitzgerald and Dix-Hallpike, caloric tests, Romberg test, tandem Gait test, Quiks test in both control and study groups...
April 2010: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/18203088/evaluation-of-the-acoustic-function-in-pseudoexfoliation-syndrome-and-exfoliation-glaucoma-audiometric-and-tympanometric-findings
#9
COMPARATIVE STUDY
E T Detorakis, F Chrysochoou, V Paliobei, A G Konstas, V Daniilidis, D Balatsouras, G Kefalidis, V P Kozobolis
PURPOSE: Previous studies have reported increased audiometric thresholds in patients with pseudoexfoliation syndrome (XFS), compared with normative data. This study examines mean audiometric thresholds and tympanometric peak values in patients with XFS and in a control group. METHODS: This is a prospective, nonrandomized control case study. Patients with XFS in one or both eyes constituted the study group (SG). Patients without XFS in either eye constituted the control group (CG)...
January 2008: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/18187196/sensorineural-hearing-loss-in-pseudoexfoliation-syndrome
#10
Shahin Yazdani, Adib Tousi, Mohammad Pakravan, Ali-Reza Faghihi
PURPOSE: To determine hearing thresholds at sound frequencies important for speech comprehension in subjects with ocular pseudoexfoliation and to compare them with that of age- and sex-matched controls without pseudoexfoliation. DESIGN: Case-control study. PARTICIPANTS: Eighty-three subjects with ocular pseudoexfoliation and 83 age- and gender-matched controls without pseudoexfoliation. METHODS: Pure tone audiometry (air and bone conduction) was performed at 1, 2, and 3 kilohertzes in all subjects...
March 2008: Ophthalmology
https://www.readbyqxmd.com/read/17361242/sensorineural-hearing-loss-in-pseudoexfoliation
#11
M Erol Turacli, Filiz A Ozdemir, Oya Tekeli, Kürsat Gökcan, Muharrem Gerçeker, Kudret Dürük
BACKGROUND: Pseudoexfoliation (PEX), which affects anterior segment structures, is thought to be a systemic disorder. The purpose of this study was to determine the possible relation between PEX and sensorineural hearing loss. METHODS: The study group included 51 patients with PEX and 22 controls without PEX. The patients and controls underwent complete ophthalmic and otorhinolaryngologic examinations. Hearing levels were evaluated with audio-tympanogram battery in all cases, and pure-tone audiogram hearing levels were classified into 6 groups...
February 2007: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/16952092/homocysteine-levels-in-plasma-and-sensorineural-hearing-loss-in-patients-with-pseudoexfoliation-syndrome
#12
B Aydoğan Ozkan, N Yüksel, G Keskin, O Altintaş, V L Karabaş, Y Cağlar, A Almaç
PURPOSE: To determine the incidence and severity of hearing loss in different frequencies in patients with pseudoexfoliation. Furthermore, possible links between homocysteine and pseudoexfoliation were evaluated. METHODS: Seventy-five consecutive patients with pseudoexfoliation and 75 sex- and age-matched subjects without pseudoexfoliation as control group were included in this prospective case-control study. Pure-tone audiometry was obtained in all subjects in both groups...
July 2006: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/15448778/ocular-pseudoexfoliation-associated-with-hearing-loss
#13
Reham I Shaban, Wafa M Asfour
OBJECTIVE: Ocular pseudoexfoliation (PXF) has been recently considered as a systemic disease affecting other organs as well as the eye. This prospective study is to assess the relationship between PXF and sensorineural hearing loss. METHODS: Patients attending a general ophthalmic clinic at King Hussein Medical Center, Amman, Jordan from (March 2002 through to March 2003) who were found to have ocular PXF on routine ophthalmic examination were referred to the Audiometric Department...
September 2004: Saudi Medical Journal
https://www.readbyqxmd.com/read/12032714/pseudoexfoliation-and-sensorineural-hearing-loss
#14
M Cahill, A Early, S Stack, A W Blayney, P Eustace
AIMS: There is increasing evidence that pseudoexfoliation (PXF) not only affects ocular anterior segment structures, but may also be a systemic disease. This study was undertaken to assess the relationship between PXF and sensorineural hearing loss. METHODS: Patients with PXF were identified from hospital records and underwent complete ocular examination. The sum of pure-tone hearing thresholds measured at 1, 2 and 3 kHz (HTL1,2,3) in each ear was compared with the ISO 7029 standard sex-matched, median age-associated hearing loss summed over the same frequencies (AAHL1,2,3)...
May 2002: Eye
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