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Dermatophytosis

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https://www.readbyqxmd.com/read/29323069/recurrent-dermatophytosis-a-rising-problem-in-sikkim-a-himalayan-state-of-india
#1
Rekha Sharma, Luna Adhikari, Rukma Lall Sharma
Changing pattern of dermatophytic infection among people of Sikkim over the past few years and its recurrence rate has brought a need to do a study on clinical pattern and its recurrence from this part of the country. The objectives of this study are to discern the clinical patterns of dermatophytosis, identification of the isolated fungi to its species level and to see the pattern of its recurrence. The study was carried out from January 2015 to May 2016. A total of 192 samples were collected from the patients with clinical findings of dermatophytic infection...
October 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/29302626/epidemiological-status-of-dermatophytosis-in-guilan-north-of-iran
#2
A A Fallahi, A Rezaei-Matehkolaei, S Rezaei
Background and Purpose: The epidemiological features of dermatophytoses have been characterized in many geographical locations of Iran, but not in Guilan, North of Iran. This study was carried out to determine the distribution pattern of dermatophytoses and their relevant agents in Guilan, North of Iran, over a period of one year, from April 2010 to April 2011. Materials and Methods: The clinical samples of skin, hair, and nail from 889 outpatients (317 men vs. 572 women) were used for direct microscopy and culture...
March 2017: Advances in Medical Mycology (Iran)
https://www.readbyqxmd.com/read/29285801/tinea-faciei-in-a-central-portuguese-hospital-a-9-year-survey
#3
Ana Borges, Ana Brasileiro, Célia Galhardas, Margarida Apetato
Tinea faciei is a relatively uncommon dermatophytosis that affects the glabrous skin of the face. The aim of this study was to analyse the epidemiologic, clinical and mycological features of tinea faciei cases diagnosed at the Dermatology and Venereology Department of Hospital Santo António dos Capuchos (Lisbon, Portugal). Consecutive cases diagnosed between 2008 and 2016 were studied retrospectively. A total of 72 tinea faciei cases have been diagnosed, involving 37 male and 35 female, aged between 8 months and 86 years...
December 28, 2017: Mycoses
https://www.readbyqxmd.com/read/29259645/in-vivo-evaluation-of-galla-chinensis-solution-in-the-topical-treatment-of-dermatophytosis
#4
Kai Sun, Xu Song, RenYong Jia, Zhongqiong Yin, Yuanfeng Zou, Lixia Li, Lizi Yin, Changliang He, Xiaoxia Liang, Gang Ye, Guizhou Yue, Xinghong Zhao, Jiankang Yu
Aim: Dermatophytosis is one of the main fungal diseases in humans and animals all over the world. Galla chinensis, a traditional medicine, has various pharmacological effects. The goal of this study was to evaluate the treatment effect of Galla chinensis solution (GCS) on dermatophytosis-infected dogs (Microsporum canis, Microsporum gypseum, and Trichophyton mentagrophytes, resp.). Methods: The treatment effects of GCS were evaluated by mycological cure rates and clinical score comprised of three indices, including inflammation, hair loss, and lesion scale...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29225090/transcriptome-analysis-of-trichophyton-mentagrophytes-induced-rabbit-oryctolagus-cuniculus-dermatophytosis
#5
Wudian Xiao, Hongbing He, Yan Tong, Mingcheng Cai, Yu Shi, Buwei Liu, Jie Wang, Yinghe Qin, Songjia Lai
No abstract text is available yet for this article.
December 7, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29204417/dermatophytosis-fighting-the-challenge-conference-proceedings-and-learning-points-september-2-3-2017-pgimer-chandigarh-india
#6
Tarun Narang, Rahul Mahajan, Sunil Dogra
No abstract text is available yet for this article.
November 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/29198426/luliconazole-a-new-antifungal-against-candida-species-isolated-from-different-sources
#7
S Taghipour, N Kiasat, S Shafiei, M Halvaeezadeh, A Rezaei-Matehkolaei, A Zarei Mahmoudabadi
OBJECTIVE: Luliconazole is an inhibitor for sterol 14-α-demethylase in fungal cells with a broad-spectrum antifungal activity against dermatophytes, Candida albicans, Malassezia species, dematiaceous and hyaline hyphomycetes. Furthermore, luliconazole has been clinically used for the treatment of pityriasis versicolor, dermatophytosis, onychomycosis, cutaneous and mucocutaneous candidiasis. In the present study, we aimed to evaluate in vitro antifungal activity of luliconazole against several strains of Candida species recovered from different clinical materials...
November 29, 2017: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/29177532/-a-different-kind-of-wrestler-s-ear
#8
H Gärtner, C S L Müller, S L Becker, A Bozzato
We report the case of a 19-year-old patient who presented with recurrent circular and scaly skin changes. The patient reported wrestling as his main leisure activity. After an unsuccessful attempt at local antibiotic treatment, detailed dermatological work-up revealed the skin changes to be tinea corporis gladiatorum. According to dermatological guidelines for dermatophytosis, systemic treatment with fluconazole and local ointments containing ciclopirox olamine and ketoconazole were administered, which rapidly led to significant improvement...
November 24, 2017: HNO
https://www.readbyqxmd.com/read/29172910/comparison-of-real-time-pcr-with-fungal-culture-for-the-diagnosis-of-microsporum-canis-dermatophytosis-in-shelter-cats-a-field-study
#9
Linda S Jacobson, Lauren McIntyre, Jenny Mykusz
Objectives Fungal culture requires at least 14 days for a final result, compared with 1-3 days for PCR. The study compared a commercial real-time dermatophyte PCR panel with fungal culture in cats in a shelter setting for: (1) diagnosis of Microsporum canis infection and (2) determination of mycological cure. Methods This was a cross-sectional, observational study of cats with suspicious skin lesions or suspected exposure to dermatophytosis. Hair samples were collected for fungal culture and PCR prior to treatment and at weekly intervals until two negative culture results were obtained...
March 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29141535/sln-and-nlc-encapsulating-antifungal-agents-skin-drug-delivery-and-their-unexplored-potential-for-treating-onychomycosis
#10
Tais Gratieri, Anna Paula Krawczyk-Santos, Priscila Bianca Rodrigues da Rocha, Marcilio Cunha-Filho, Guilherme Martins Gelfuso, Ricardo Neves Marreto, Stephania Fleury Taveira
BACKGROUND: Lipid nanoparticles have been extensively studied for drug delivery of antifungal drugs, especially for dermatophytosis treatments. They can accumulate in skin appendages and release drugs in a controlled manner and also increase skin moisture, due to the formation of an occlusive film. Since moisture heavily influences nail and skin permeability, these systems seem to pose great potential for antifungal drug delivery. METHODS: We therefore compare skin and nail physiopathological structure and discuss the potential use of lipid nanoparticles in managing skin and nail mycoses, highlighting their unexplored use in onychomycosis...
November 14, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29094463/severe-dermatophytosis-in-solid-organ-transplant-recipients-a-french-retrospective-series-and-literature-review
#11
Claire Rouzaud, Olivier Chosidow, Anabelle Brocard, Sylvie Fraitag, Anne Scemla, Dany Anglicheau, Jean-David Bouaziz, Nicolas Dupin, Marie-Elisabeth Bougnoux, Roderick Hay, Olivier Lortholary, Fanny Lanternier
OBJECTIVE: Severe dermatophytosis is described in immunocompromised patients with defective cellular immunity. We report here a large series and a literature review of severe dermatophytosis in solid organ transplant (SOT) recipients. METHOD: The data main source was a national French retrospective study of severe dermatophytosis in SOT recipients between 2010 and 2016. Inclusion criteria were the presence of dermatophytes in skin culture and one severity criteria: dermal invasion by dermatophytes (invasive dermatophytosis) or involvement of at least two body sites or >10% of body surface area (extensive dermatophytosis) RESULTS: Twelve patients were included (8 men, median age of 56 years [range: 33-71])...
November 2, 2017: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/29072357/piper-regnellii-extract-biopolymer-based-microparticles-production-characterization-and-antifungal-activity
#12
Lara Zampar Serra Brambilla, Eliana Harue Endo, Diógenes Aparício Garcia Cortez, Marli Miriam de Souza Lima, Benedito Prado Dias Filho
AIMS: This study aims to improve characteristics of Piper regnellii extract to make it applicable in formulations to treat dermatophytosis, also known as ringworm. METHODS AND RESULTS: Microparticles were produced by spray-drying with gelatin, alginate and chitosan as encapsulating agents, characterized by scanning electron microscopy, encapsulation efficiency, thermal analyses, X-ray diffraction, and tested against Trichophyton rubrum by broth microdilution. Produced microparticles had a mean diameter less than 2 μm, an increase in stability and release of the extract and good results for encapsulation efficiency, being 85...
October 26, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29067631/dermatomycoses-due-to-nannizzia-praecox-formerly-microsporum-praecox-in-germany-case-reports-and-review-of-the-literature
#13
REVIEW
Silke Uhrlaß, Peter Mayser, Roman Schwarz, Daniela Koch, Constanze Krüger, Irene Korfmann, Pietro Nenoff
Nannizzia praecox, formerly known as Microsporum praecox, is a geophilic dermatophyte. Up to now 31 cases of human tinea have been reported in the literature, most of them with an inflammatory course. Three recent cases diagnosed in Germany within 1 year suggest that the fungus might be a more common cause of human dermatophytosis than reported so far. This might be based on the fact that N. praecox is often found in an equine environment and that horse riding is becoming more popular recently.
October 24, 2017: Mycopathologia
https://www.readbyqxmd.com/read/28992062/epidemiology-of-human-dermatophytoses-in-africa
#14
Oumar Coulibaly, Coralie L'Ollivier, Renaud Piarroux, Stéphane Ranque
In this critical literature review, we summarize the epidemiological trends of dermatophytoses reported in Africa. Our findings clearly emphasize the heavy burden of dermatophytosis in Africa. Tinea capitis is the primary clinical presentation of dermatophytosis in African children throughout the entire African continent. The disease affects more than 20% of school-age children in West Africa, while the prevalence ranges from 10% to more than 70% in other regions of Africa. In African adults, the presence of tinea corporis is the most frequent indicator of dermatophytosis...
July 28, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/28979861/treatment-of-dermatophytosis-in-elderly-children-and-pregnant-women
#15
REVIEW
Subuhi Kaul, Savita Yadav, Sunil Dogra
Dermatophytic infection of the skin and its appendages is a common occurrence. Though usually straightforward, treatment of dermatophytosis becomes notably challenging in certain population groups - pregnant women, children, and elderly. Treatment with topical azoles/allylamines alone is effective in limited cutaneous disease in all three groups. Terbinafine is the preferred oral agent in elderly population for treatment of extensive cutaneous disease and onychomycosis due to its lack of cardiac complications and lower propensity for drug interactions...
September 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/28960268/mucocutaneous-manifestations-in-human-immunodeficiency-virus-hiv-infected-patients-in-nouakchott-mauritania
#16
Boushab M Boushab, Fatim-Zahra Malick Fall, Taleb K Ould Cheikh Mohamed Vadel, Mohamed L Ould Cheikh Melaïnine, Mohamed V Maazouz, Mamoudou Savadogo, Leonardo K Basco
BACKGROUND: Mucocutaneous manifestations are one of the first clinical signs in patients infected with human immunodeficiency virus (HIV). To the best of our knowledge, there has been no previous study describing dermatologic manifestations in Mauritanians infected with HIV. The aim of the present study was to determine the profiles of mucocutaneous manifestations in relation to CD4 T cell count in HIV-positive Mauritanian patients. METHODS: A total of 86 adult patients aged > 18 years old attending the Ambulatory Treatment Center of the National Hospital of Nouakchott, Mauritania, with newly diagnosed HIV and who were not under antiretroviral treatment were included in the study in 2015...
September 27, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28959790/proteolytic-activity-and-cooperative-hemolytic-effect-of-dermatophytes-with-different-species-of-bacteria
#17
K Pakshir, T Mohamadi, H Khodadadi, M Motamedifar, K Zomorodian, S Alipour, M Motamedi
BACKGROUND AND PURPOSE: Globally, dermatophytes are the most common filamentous group of fungi causing cutaneous mycoses. Dermatophytes were shown to secrete a multitude of enzymes that play a role in their pathogenesis. There is limited data on co-hemolytic (CAMP-like) effect of different bacterial species on dermatophyte species. In this study, we sought to the evaluate exoenzyme activity and co-hemolytic effect of four bacteria on clinical dermatophytes isolated from patients in Shiraz, Iran...
December 2016: Advances in Medical Mycology (Iran)
https://www.readbyqxmd.com/read/28947778/an-invertebrate-infection-model-for-evaluating-anti-fungal-agents-against-dermatophytosis
#18
Masaki Ishii, Yasuhiko Matsumoto, Tsuyoshi Yamada, Shigeru Abe, Kazuhisa Sekimizu
Animal models of pathogenic infection are needed to evaluate candidate compounds for the development of anti-infectious drugs. Dermatophytes are pathogenic fungi that cause several infectious diseases. We established a silkworm dermatophyte infection model to evaluate anti-fungal drugs. Injection of conidia of the dermatophyte Arthroderma vanbreuseghemii into silkworms was lethal. A. vanbreuseghemii conidia germinated in liquid culture were more potent against silkworms than non-germinated conidia. Germinated conidia of other dermatophytes, Arthroderma benhamiae, Trichophyton rubrum, and Microsporum canis, also killed silkworms...
September 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28936991/intracutaneous-pharmacokinetics-of-oral-antifungals-and-their-relevance-in-recalcitrant-cutaneous-dermatophytosis-time-to-revisit-basics
#19
Kabir Sardana, Pooja Arora, Khushbu Mahajan
No abstract text is available yet for this article.
September 21, 2017: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/28920535/evaluation-of-incubation-time-for-microsporum-canis-dermatophyte-cultures
#20
Rebecca Stuntebeck, Karen A Moriello, Maria Verbrugge
Objectives The goal of this study was to determine how frequently Microsporum canis was isolated after 1, 2 and 3 weeks of incubation on dermatophyte culture medium either from untreated cats or cats during treatment. Methods This was an observational retrospective study. Toothbrush fungal culture results were examined from two data pools: untreated cats with suspect skin lesions and weekly fungal cultures from cats being treated for dermatophytosis. Results Results from 13,772 fungal cultures were reviewed and 2876 (20...
September 1, 2017: Journal of Feline Medicine and Surgery
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