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Dermatophytosis

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https://www.readbyqxmd.com/read/28340215/development-of-enzyme-immunoassays-elisa-and-western-blot-for-the-serological-diagnosis-of-dermatophytosis-in-symptomatic-and-asymptomatic-cats
#1
Aline Elisa Santana, Carlos Pelleschi Taborda, Julia So Severo, Glauce Mary Gomes Rittner, Julian Esteban Muñoz, Carlos Eduardo Larsson, Carlos Eduardo Larsson
Dermatophytosis is the most common fungal infection in cats worldwide and plays an important role in both animal and human health due to their high zoonotic potential. Effective screening is a strong preventive measure and the fungal culture is quite useful but requires full laboratorial experience and it takes a long time to obtain the result. A rapid and accurate screening test for dermatophytosis in cats is crucial for the effective control of disease outbreaks. The aim of this study was to develop and evaluate the diagnostic efficacy of enzyme immunoassays (ELISA and Western blot [WB]) for the rapid and precise diagnosis of dermatophytosis in cats...
March 11, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/28327819/cellular-immunodeficiency-related-to-chronic-dermatophytosis-in-a-patient-with-schistosoma-mansoni-infection-can-schistosomiasis-induce-immunodeficiency
#2
Maurício Domingues Ferreira, Anna Cristina Collaniere, Dalton Luís Bertolini, Noac Chuffi Barros, Dewton de Moraes Vasconcelos
Here, we describe a case of hepatosplenic schistosomiasis that progressed to widespread persistent dermatophytosis. Significant T and B lymphocytopenia was confirmed. T-cell deficit is associated with increased susceptibility to fungal infections of skin and mucous membranes. The accumulation of a large amount of blood cells in the spleen could have played a crucial role in the development of lymphocytopenia in the present case. Alternatively, the schistosomiasis-induced increase in prostaglandin E2 levels could have inhibited the production of interferon-γ, a cytokine fundamental to fungal resistance...
January 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/28278668/chemical-characterisation-and-biological-activity-of-leaf-essential-oils-obtained-from-pistacia-terebinthus-growing-wild-in-tunisia-and-sardinia-island
#3
Alessandra Piras, Hanen Marzouki, Andrea Maxia, Arianna Marengo, Silvia Porcedda, Danilo Falconieri, Maria José Gonçalves, Carlos Cavaleiro, Ligia Salgueiro
In the present work the chemical compositions, measured by GC and GC-MS, of the essential oils obtained by hydrodistillation from leaves of Pistacia terebinthus collected in Bizerte (Tunisia) and Baunei (Italy) are reported. Both essential oils possessed high content of monoterpene hydrocarbons (86.3% and 90.9%, respectively), being α-pinene (62.4 vs. 35.0)%, camphene (3.0 vs. 2.4)%, β-pinene (12.1 vs. 4.5)%, terpinolene (1.7 vs. 35.2)% and β-phellandrene (3.8 vs. 4.5)% the main components. The Tunisian essential oil exhibited higher antifungal activity than the Italian one...
February 15, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28214274/intra-abdominal-fungal-pseudomycetoma-in-two-cats
#4
Matheus V Bianchi, Cláudio J M Laisse, Thainã P Vargas, Flademir Wouters, Fabiana M Boabaid, Saulo P Pavarini, Laerte Ferreiro, David Driemeier
BACKGROUND: Pseudomycetomas are deep cutaneous to subcutaneous lesions caused by Microsporum canis mainly described in Persian cats, with few reports of intra-abdominal location. This report describes the clinical signs and lesions of intra-abdominal pseudomycetomas caused by M. canis in two Persian cats. CASE REPORT: Two Persian cats with a history of previous laparotomy (ovariohysterectomy and nephrostomy) and fecal impaction were examined. Cat #1 was euthanized and subjected to necropsy, histopathology and mycological evaluation...
February 14, 2017: Revista Iberoamericana de Micología
https://www.readbyqxmd.com/read/28208985/pattern-of-inpatient-dermatology-consultations-in-a-tertiary-care-centre-from-northern-india
#5
Abhilasha Williams, Anuradha Bhatia, Bimal Kanish, Paulina Rose Chaudhary, Clarence James Samuel
INTRODUCTION: The importance of dermatology inpatient consultation is of significant importance yet is not well documented. AIM: To retrospectively analyse the spectrum of dermatology inpatient consultations from the various departments and to document the most commonly occurring dermatological disorders from each speciality. MATERIALS AND METHODS: This study was done in an 800 bedded premier teaching hospital in Ludhiana, Punjab, North Western India...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28198097/inibitory-effects-of-linalool-on-fungal-pathogenicity-of-clinical-isolates-of-microsporum-canis-and-microsporum-gypseum
#6
Kaltz V S Silva, Maria I O Lima, Gustavo N Cardoso, Aldeir S Santos, Gezaíldo S Silva, Fillipe O Pereira
In humans worldwide, Microsporum sp. is a frequent agent of dermatophytsosis. When considering the emergence of resistant fungi and the clinical relevance of dermatophytosis, terpene antifungal activity is of great interest. Linalool is a monoterpene alcohol with pharmacological properties. In this study, antifungal in vitro activity of linalool and ketoconazole (as a positive control) were evaluated against clinical isolates of M. canis and M. gypseum. The minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of each drug were determined by broth microdilution...
February 15, 2017: Mycoses
https://www.readbyqxmd.com/read/28195092/efficacy-of-in-house-fluorescent-stain-for-fungus
#7
K R L Surya Kirani, V Satya Chandrika
CONTEXT: Mycotic infections are gaining importance in the present day medicine, and definite demonstration of fungus is essential for diagnosis. Small numbers of organisms in the smear can be identified by fluorescence microscopy. Calcofluor white (CFW) fluorescent stain is a textile brightener mixed with Evans blue. It is expensive and not easily available. AIMS: (1) To assess the efficacy of in-house CFW fluorescent stain for fungus in relation to conventional CFW stain, histopathology, and culture...
January 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28183589/terbinafine-loaded-wound-dressing-for-chronic-superficial-fungal-infections
#8
Farnoush Asghari Paskiabi, Shahin Bonakdar, Mohammad Ali Shokrgozar, Mohammad Imani, Zahra Jahanshiri, Masoomeh Shams-Ghahfarokhi, Mehdi Razzaghi-Abyaneh
In spite of developing new drugs and modern formulations, the treatments of chronic fungal infections are still challenging. Fibrous wound dressings are new suggestions for the treatment of chronic superficial infections. In the present study, we formulated an antifungal agent, terbinafine hydrochloride (TFH), which is a hydrophobic drug, in wound dressings prepared by electrospun polycaprolactone, polycaprolactone/gelatin (50:50 w/w) and gelatin. To obtain more water-stable meshes, the preparations were treated by glutaraldehyde and their properties were determined before and after treatment...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28164040/tlr2-mice-display-increased-clearance-of-dermatophyte-trichophyton-mentagrophytes-in-the-setting-of-hyperglycemia
#9
Débora de Fátima Almeida, Thais F de Campos Fraga-Silva, Amanda R Santos, Angela C Finato, Camila M Marchetti, Marjorie de Assis Golim, Vanessa S Lara, Maria S P Arruda, James Venturini
Dermatophytosis is one of the most common human infections affecting both immunocompetent individuals and immunocompromised patients, in whom the disease is more aggressive and can reach deep tissues. Over the last decades, cases of deep dermatophytosis have increased and the dermatophyte-host interplay remains poorly investigated. Pattern recognition molecules, such as Toll-like receptors (TLR), play a crucial role against infectious diseases. However, there has been very little research reported on dermatophytosis...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28154954/deep-dermatophytosis-caused-by-zoophilic-strain-of%C3%A2-trichophyton-interdigitale%C3%A2-with-successful-treatment-of-itraconazole
#10
Hsuan-An Su, Pei-Lun Sun, Wen-Wei Sung, Su-Ya Cheng, Hui-Chin Chang, Jen-Hung Yang, Yu-Ping Hsiao
We report a 66-year-old female patient with deep dermatophytosis caused by zoophilic strain of Trichophyton interdigitale, a rare granulomatous presentation of Trichophyton species infection in patients with underlying systemic diseases, and she was successfully cured by itraconazole. Since the identification of Trichophyton mentagrophytes complex had been misused for years, a brief discussion of molecular diagnosis and taxonomy of T. mentagrophytes complex is given. The pathogenesis and comparison with cases reported in the literature are also discussed...
February 2, 2017: Mycopathologia
https://www.readbyqxmd.com/read/28116455/-dermatophyte-current-situation
#11
REVIEW
P Mayser
Currently, a mycid is defined as hyperergic reaction that develops from a remote localized infection and in which no fungus is detectable. Criteria for a mycid caused by a dermatophyte (dermatophytid) are (1) proven dermatophytosis elsewhere, (2) no evidence for fungal elements in the lesions of the -id reaction, (3) initially often worsening of the lesions under therapy with highly potent systemic antimycotics, and (4) clearing after the dermatophytosis has been treated sufficiently. The most common dermatophytid is a symmetrical dyshidrotic mycid of the hands in connection with an often highly inflammatory mycotic infection of the feet especially by Trichophyton mentagrophytes...
January 23, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28101694/relationship-between-phenotypic-and-genotypic-characteristics-of-trichophyton-mentagrophytes-strains-isolated-from-patients-with-dermatophytosis
#12
I Dhib, I Khammari, A Yaacoub, F Hadj Slama, M Ben Saïd, R Zemni, A Fathallah
According to epidemiological, clinical and mycological criteria, it has long been admitted that the Trichophyton mentagrophytes species includes two varieties: a zoophilic variety (var. mentagrophytes) and an anthropophilic variety (var. interdigitale) that involve the upper and the lower part of the body, respectively. The further application of molecular techniques to the characterization of dermatophyte strains showed that this classification is unreliable. The aim of our study was to assess the usefulness of PCR-RFLP (restriction fragment length polymorphism) and sequencing in the characterization of T...
January 18, 2017: Mycopathologia
https://www.readbyqxmd.com/read/28099610/dermatophytosis-caused-by-microsporum-gypseum-in-infants-report-of-four-cases-and-review-of-the-literature
#13
Beatriz da Silva Souza, Débora Sarzi Sartori, Carin de Andrade, Edna Weisheimer, Ana Elisa Kiszewski
Dermatophytosis caused by Microsporum gypseum is rare, especially in infants, with few published cases. Diagnosis in this age group is frequently delayed. We review the literature and report 4 new cases of tinea of glabrous skin caused by M. gypseum mimicking eczema in infants. Considering new and previously reported cases, half of patients were exposed to sand, emphasizing the importance of this transmission vehicle in this age group. In conclusion, although rare, dermatophytosis by M. gypseum should be part of the differential diagnosis of inflammatory dermatosis in infants...
November 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28066103/efficacy-and-tolerability-of-topical-sertaconazole-versus-topical-terbinafine-in-localized-dermatophytosis-a-randomized-observer-blind-parallel-group-study
#14
Dattatreyo Chatterjee, Sudip Kumar Ghosh, Sukanta Sen, Saswati Sarkar, Avijit Hazra, Radharaman De
OBJECTIVE: Epidermal dermatophyte infections most commonly manifest as tinea corporis or tinea cruris. Topical azole antifungals are commonly used in their treatment but literature suggests that most require twice-daily application and provide lower cure rates than the allylamine antifungal terbinafine. We conducted a head-to-head comparison of the effectiveness of the once-daily topical azole, sertaconazole, with terbinafine in these infections. MATERIALS AND METHODS: We conducted a randomized, observer-blind, parallel group study (Clinical Trial Registry India [CTRI]/2014/09/005029) with adult patients of either sex presenting with localized lesions...
November 2016: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/28050591/trichophyton-rubrum-tinea-capitis-in-an-hiv-positive-patient-with-generalized-dermatophytosis
#15
Caely A Hambro, Natalie C Yin, Christine Yang, Sameera Husain, David N Silvers, Marc E Grossman
No abstract text is available yet for this article.
January 2017: JAAD Case Reports
https://www.readbyqxmd.com/read/28010906/zoonotic-disease-risk-perceptions-in-the-british-veterinary-profession
#16
Charlotte Robin, Judy Bettridge, Fiona McMaster
In human and veterinary medicine, reducing the risk of occupationally-acquired infections relies on effective infection prevention and control practices (IPCs). In veterinary medicine, zoonoses present a risk to practitioners, yet little is known about how these risks are understood and how this translates into health protective behaviour. This study aimed to explore risk perceptions within the British veterinary profession and identify motivators and barriers to compliance with IPCs. A cross-sectional study was conducted using veterinary practices registered with the Royal College of Veterinary Surgeons...
January 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28004227/trichophyton-rubrum-infection-characterized-by-majocchi-s-granuloma-and-deeper-dermatophytosis-case-report-and-review-of-published-literature
#17
Huilin Su, Li Li, Benlin Cheng, Junhao Zhu, Qiangqiang Zhang, Jinhua Xu, Min Zhu
Infections caused by Trichophyton rubrum are very common in dermatological disease. It most often appears as superficial cutaneous mycosis, such as tinea manuum, tinea pedis, and tinea corporis. However, deep infection caused by T. rubrum was rarely reported. We describe a case of mixed type of deep infection caused by T. rubrum in a 45-year-old man with no significant immunodeficiency. This patient had a history of onychomycosis on the toenails without regular treatment for nearly 6 years. And, he had erythema, papule, and nodules on the submandibular area, neck, and chest for almost 1 year...
December 21, 2016: Mycopathologia
https://www.readbyqxmd.com/read/27935915/medication-practice-of-patients-with-dermatophytosis
#18
Y Poudyal, S D Joshi
INTRODUCTION: Dermatophytosis is one of the commonest dermatoses observed in Dermatology OPD. It is caused by Fungus Dermatophyte. Its pattern and prevalence varies from region to region. As self medication practice is very common, we aim to find the prevalence of various clinical pattern of dermatophytosis and to find out the medication commonly used by the patients for this condition. METHODS: This was cross sectional observational study. The case collection was done from outpatient department of Dermatology and Venereology of a Teaching Hospital from 15th March, 2013 to 14 March, 2014...
July 2016: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/27929279/pet-related-infections
#19
Michael J Day
Physicians and veterinarians have many opportunities to partner in promoting the well-being of people and their pets, especially by addressing zoonotic diseases that may be transmitted between a pet and a human family member. Common cutaneous pet-acquired zoonoses are dermatophytosis (ringworm) and sarcoptic mange (scabies), which are both readily treated. Toxoplasmosis can be acquired from exposure to cat feces, but appropriate hygienic measures can minimize the risk to pregnant women. Persons who work with animals are at increased risk of acquiring bartonellosis (e...
November 15, 2016: American Family Physician
https://www.readbyqxmd.com/read/27897199/hydroxychavicol-a-phytochemical-targeting-cutaneous-fungal-infections
#20
Intzar Ali, Naresh Kumar Satti, Prabhu Dutt, Rajendra Prasad, Inshad Ali Khan
The present study was designed to investigate the potency of hydroxychavicol on selected cutaneous human pathogenic fungi by the use of in vitro and in vivo assays and mechanistic characterization along with toxicological effects. Hydroxychavicol consistently displayed a fungicidal effect against all fungal species tested. Inoculum concentrations over the range of 10(4) to 10(7) CFU/ml did not significantly alter its antifungal potential and time-kill curve results revealed concentration-dependent killing...
November 29, 2016: Scientific Reports
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