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https://www.readbyqxmd.com/read/28932737/technical-intraoperative-maneuvers-for-the-management-of-inferior-vena-cava-thrombus-in-renal-cell-carcinoma
#1
Dionysios Dellaportas, Nikolaos Arkadopoulos, Ioannis Tzanoglou, Evgenios Bairamidis, George Gemenetzis, Pantelis Xanthakos, Constantinos Nastos, Georgia Kostopanagiotou, Ioannis Vassiliou, Vassilios Smyrniotis
INTRODUCTION: Renal vein or inferior vena cava (IVC) invasion by neoplastic thrombus in patients with renal cell carcinoma (RCC) is not an obstacle for radical oncological treatment. The aim of this study is to present our technical maneuvers for complete removal of the intracaval thrombus without compromising hemodymanic stability of the patient. MATERIALS AND METHODS: Between 2000 and 2014, 15 RCC patients with IVC involvement of levels I-III were treated with curative intent and were prospectively studied...
2017: Frontiers in Surgery
https://www.readbyqxmd.com/read/28932585/an-unusually-large-paraesophageal-hernia-mimicking-a-bochdalek-hernia
#2
Daneish Selvakumar, Karan Sian, Ajay J Iyengar, Ross Mejia
Hiatal hernias are due to defects in the esophageal hiatus in the diaphragm and can be classified into sliding or paraesophageal hernias. A 31-year-old male raised a suspicion of a Bochdalek hernia but at surgery had a large paraesophageal hernia. Bochdalek hernia, a congenital diaphragmatic hernia presents in adulthood asymptomatically or with vague abdominal symptoms. It is paramount to confirm the diagnosis and rule out any fatal complications with imaging studies. Prompt surgical management with large complicated hernias, such as in our case presentation would ensure the most favorable outcome...
August 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28930478/mechanical-ventilation-induced-diaphragm-atrophy-strongly-impacts-clinical-outcomes
#3
Ewan C Goligher, Martin Dres, Eddy Fan, Gordon D Rubenfeld, Damon C Scales, Margaret S Herridge, Stefannie Vorona, Michael C Sklar, Nuttapol Rittayamai, Ashley Lanys, Alistair Murray, Deborah Brace, Cristian Urrea, W Darlene Reid, George Tomlinson, Arthur S Slutsky, Brian P Kavanagh, Laurent J Brochard, Niall D Ferguson
Rationale Diaphragm dysfunction worsens outcomes in mechanically ventilated patients but the clinical impact of potentially preventable changes in diaphragm structure and function due to mechanical ventilation is unknown. Objectives To determine whether diaphragm atrophy developing during mechanical ventilation leads to prolonged ventilation. Methods Diaphragm thickness was measured daily by ultrasound in adults requiring invasive mechanical ventilation; inspiratory effort was assessed by thickening fraction...
September 20, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28928772/tissue-engineering-to-repair-diaphragmatic-defect-in-a-rat-model
#4
G P Liao, Y Choi, K Vojnits, H Xue, K Aroom, F Meng, H Y Pan, R A Hetz, C J Corkins, T G Hughes, F Triolo, A Johnson, Kenneth J Moise, K P Lally, C S Cox, Y Li
Tissue engineering is an emerging strategy for repairing damaged tissues or organs. The current study explored using decellularized rat diaphragm scaffolds combined with human amniotic fluid-derived multipotent stromal cells (hAFMSC) to provide a scaffold, stem cell construct that would allow structural barrier function during tissue ingrowth/regeneration. We created an innovative cell infusion system that allowed hAFMSC to embed into scaffolds and then implanted the composite tissues into rats with surgically created left-sided diaphragmatic defects...
2017: Stem Cells International
https://www.readbyqxmd.com/read/28924092/extralobar-pulmonary-sequestration-in-two-pinniped-species
#5
Shotaro Nakagun, Hirotaka Watanabe, Kenji Ochiai, Kaoru Kohyama, Wataru Goshima, Yoko Goto, Yumi Kobayashi, Kennichi Watanabe, Noriyuki Horiuchi, Jun Sasaki, Masanobu Goryo, Yoshiyasu Kobayashi
Two cases of extralobar pulmonary sequestrations from a walrus (Odobenus rosmarus) and a Steller sea lion (Eumetopias jubatus) are described in the present study. Grossly, an independent, soft unilocular cystic mass was found within the abdominal cavities of both animals, adherent to the diaphragm in O. rosmarus and attached to the cardia of the stomach in E. jubatus. Histopathologically, the cysts were lined by pseudostratified ciliated columnar epithelium with abundant goblet cells, while the wall comprised of glands, hyaline cartilage, bronchiole- and alveolus-like structures, smooth muscles, and large, well-developed elastic and muscular arteries...
September 17, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28923678/a-case-report-on-gastric-volvulus-of-a-17-years-old-boy-from-bangladesh
#6
M Tasdik Hasan, S M Tajdit Rahman, Hasan M Shihab, Hassan Rushekh Mahmood, Tanni Chowdhury, Quamrul Akhtar Sanju
INTRODUCTION: Gastric volvulus is a rare and true surgical emergency which is life threatening if not recognized and treated quickly. There have been approximately 300 reported cases globally till now. This condition most often occurs during 5th decade of life but there are over 100 reported pediatric cases also. This following rare incidence was such a case of a young patient in Bangladesh. It was the first case of gastric volvulus managed by the surgery department of the concerned hospital...
September 7, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28922361/impact-of-four-different-recumbencies-on-the-distribution-of-ventilation-in-conscious-or-anaesthetized-spontaneously-breathing-beagle-dogs-an-electrical-impedance-tomography-study
#7
Tamas D Ambrisko, Johannes P Schramel, Ulrike Auer, Yves P S Moens
The aim was to examine the effects of recumbency and anaesthesia on distribution of ventilation in beagle dogs using Electrical Impedance Tomography (EIT). Nine healthy beagle dogs, aging 3.7±1.7 (mean±SD) years and weighing 16.3±1.6 kg, received a series of treatments in a fixed order on a single occasion. Conscious dogs were positioned in right lateral recumbency (RLR) and equipped with 32 EIT electrodes around the thorax. Following five minutes of equilibration, two minutes of EIT recordings were made in each recumbency in the following order: RLR, dorsal (DR), left (LLR) and sternal (SR)...
2017: PloS One
https://www.readbyqxmd.com/read/28917595/perioperative-and-oncologic-outcomes-of-nephrectomy-and-caval-thrombectomy-using-extracorporeal-circulation-and-deep-hypothermic-circulatory-arrest-for-renal-cell-carcinoma-invading-the-supradiaphragmatic-inferior-vena-cava-and-or-right-atrium
#8
Alessandro Nini, Umberto Capitanio, Alessandro Larcher, Paolo Dell'Oglio, Federico Dehò, Nazareno Suardi, Fabio Muttin, Cristina Carenzi, Massimo Freschi, Roberta Lucianò, Giovanni La Croce, Alberto Briganti, Renzo Colombo, Andrea Salonia, Alessandro Castiglioni, Patrizio Rigatti, Francesco Montorsi, Roberto Bertini
BACKGROUND: Radical nephrectomy (RN) and caval thrombectomy (CT) for renal cell carcinoma, with extracorporeal circulation (ECC) and deep hypothermic circulatory arrest (DHCA) is a challenging surgical approach. OBJECTIVE: To assess peri-operative and oncologic outcomes of renal cell carcinoma patients treated with RN and CT, using ECC and DHCA. DESIGN, SETTING, AND PARTICIPANTS: We retrospectively evaluated 46 patients who underwent RN and CT using ECC and DHCA...
September 13, 2017: European Urology
https://www.readbyqxmd.com/read/28917004/critical-illness-associated-diaphragm-weakness
#9
REVIEW
Martin Dres, Ewan C Goligher, Leo M A Heunks, Laurent J Brochard
Diaphragm weakness is highly prevalent in critically ill patients. It may exist prior to ICU admission and may precipitate the need for mechanical ventilation but it also frequently develops during the ICU stay. Several risk factors for diaphragm weakness have been identified; among them sepsis and mechanical ventilation play central roles. We employ the term critical illness-associated diaphragm weakness to refer to the collective effects of all mechanisms of diaphragm injury and weakness occurring in critically ill patients...
September 15, 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/28916788/a-v0-core-neuronal-circuit-for-inspiration
#10
Jinjin Wu, Paolo Capelli, Julien Bouvier, Martyn Goulding, Silvia Arber, Gilles Fortin
Breathing in mammals relies on permanent rhythmic and bilaterally synchronized contractions of inspiratory pump muscles. These motor drives emerge from interactions between critical sets of brainstem neurons whose origins and synaptic ordered organization remain obscure. Here, we show, using a virus-based transsynaptic tracing strategy from the diaphragm muscle in the mouse, that the principal inspiratory premotor neurons share V0 identity with, and are connected by, neurons of the preBötzinger complex that paces inspiration...
September 15, 2017: Nature Communications
https://www.readbyqxmd.com/read/28914623/prevalence-and-prognosis-impact-of-patient-ventilator-asynchrony-in-early-phase-of-weaning-according-to-two-detection-methods
#11
Camille Rolland-Debord, Côme Bureau, Tymothee Poitou, Lisa Belin, Marc Clavel, Sébastien Perbet, Nicolas Terzi, Achille Kouatchet, Thomas Similowski, Alexandre Demoule
BACKGROUND: Patient-ventilator asynchrony is associated with a poorer outcome. The prevalence and severity of asynchrony during the early phase of weaning has never been specifically described. The authors' first aim was to evaluate the prognosis impact and the factors associated with asynchrony. Their second aim was to compare the prevalence of asynchrony according to two methods of detection: a visual inspection of signals and a computerized method integrating electromyographic activity of the diaphragm...
September 14, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28910917/-the-advances-in-vetilator-induced-diaphragm-dysfunction
#12
X H Wang, L D Li
No abstract text is available yet for this article.
September 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28904987/respiratory-magnetic-resonance-imaging-biomarkers-in-duchenne-muscular-dystrophy
#13
Ami Mankodi, William Kovacs, Gina Norato, Nathan Hsieh, W Patricia Bandettini, Courtney A Bishop, Hirity Shimellis, Rexford D Newbould, Eunhee Kim, Kenneth H Fischbeck, Andrew E Arai, Jianhua Yao
OBJECTIVE: To examine the diaphragm and chest wall dynamics with cine breathing magnetic resonance imaging (MRI) in ambulatory boys with Duchenne muscular dystrophy (DMD) without respiratory symptoms and controls. METHODS: In 11 DMD boys and 15 controls, cine MRI of maximal breathing was recorded for 10 sec. The lung segmentations were done by an automated pipeline based on a Holistically-Nested Network model (HNN method). Lung areas, diaphragm, and chest wall motion were measured throughout the breathing cycle...
September 2017: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/28904359/structured-illumination-microscopy-and-automatized-image-processing-as-a-rapid-diagnostic-tool-for-podocyte-effacement
#14
Florian Siegerist, Silvia Ribback, Frank Dombrowski, Kerstin Amann, Uwe Zimmermann, Karlhans Endlich, Nicole Endlich
The morphology of podocyte foot processes is obligatory for renal function. Here we describe a method for the superresolution-visualization of podocyte foot processes using structured illumination microscopy of the slit diaphragm, which before has only been achieved by electron microscopy. As a proof of principle, we measured a mean foot process width of 0.249 ± 0.068 µm in healthy kidneys and a significant higher mean foot process width of 0.675 ± 0.256 µm in minimal change disease patients indicating effacement of foot processes...
September 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28903915/obesity-modulates-diaphragm-curvature-in-subjects-with-and-without-copd
#15
Aladin M Boriek, Michael A Lopez, Cristina Velasco, Azam A Bakir, Anna Frolov, Shari Wynd, Tony G Babb, Nicola A Hanania, Eric A Hoffman, Amir Sharafkhaneh
BACKGROUND: Obesity is a common co-morbidity of COPD and has been associated with worse outcomes. However, it is unknown whether the interaction between obesity and COPD modulates diaphragm shape and consequently its function. The body mass index has been used as a correlate of obesity. We tested the hypothesis that the shape of the diaphragm muscle and size of the ring of its insertion in Non-COPD and COPD subjects are modulated by BMI. METHODS: We recruited 48 COPD patients with post-bronchiodilator FEV1/FVC < 0...
September 13, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28902822/assessing-the-effect-of-endoprosthetic-repair-of-the-thoracic-portion-on-aortic-remodelling-after-surgical-correction-for-debakey-type-i-dissection
#16
V V Bazylev, M G Shmatkov, D A Zakharov, Z A Morozov
OBJECTIVE: The purpose of the study was to evaluate the influence of endoprosthetic repair of the aortic thoracic portion on remodelling of the descending aorta in patients after the surgical stage of correction for DeBakey type I aortic dissection. PATIENTS AND METHODS: The authors retrospectively analysed a group of 12 patients (9 men and 3 women) subjected to endoprosthetic repair of the aortic thoracic portion after previously performed surgical correction of the ascending aorta and its braches...
2017: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/28901960/sudden-death-in-an-adult-due-to-nontraumatic-diaphragmatic-hernia
#17
Hideaki Kato, Yasuhiro Aoki, Jun Ohtaki, Yoshimi Nakamura, Mohammed Hassan Gaballah, Mamiko Fukuta, Katsumasa Kobayashi
Sudden death due to diaphragmatic hernia in an adult is exceptionally rare. A 43-year-old man was found dead by his cohabiting mother, lying supine on the floor in his house. He had complained of epigastric discomfort for 1 month, and respiratory symptoms occurred 1 day before his death. He had no history of trauma. Postmortem computed tomography scan revealed the enlarged fluid-filled stomach herniated into the left pleural cavity, compressing the left lung with a mediastinal shift to the right. At autopsy, the left pleural cavity was occupied by herniated abdominal contents with mediastinal shift...
September 9, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28900226/a-controllable-and-integrated-pump-enabled-microfluidic-chip-and-its-application-in-droplets-generating
#18
Bei Zhao, Xingye Cui, Wei Ren, Feng Xu, Ming Liu, Zuo-Guang Ye
A microfluidic chip with a controllable and integrated piezoelectric pump was proposed and demonstrated, where the pump was designed as a micro-actuator based on polyvinylidene fluoride (PVDF) organic piezoelectric film. In this case, the pump should integrate with the microfluidics device very well into one chip. The flow rate can be precisely controlled in the range of 0-300 µl/min for water by tuning the Vpp and frequency of Alternating Current (AC) voltage applied on the diaphragm. To analyze the relationship between the flow rate and the deflection of diaphragm, the deformations of diaphragm at different voltages were researched...
September 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28900040/reduced-diaphragm-excursion-during-reflexive-citric-acid-cough-test-in-subjects-with-subacute-stroke
#19
Yong-Min Choi, Geun-Young Park, Yeonji Yoo, Donggyun Sohn, YongJun Jang, Sun Im
BACKGROUND: Diaphragm excursion is limited during respiratory maneuvers after a stroke. How the diaphragm is limited during reflexive coughs and affects the effectiveness of cough in stroke patients is unclear. This study aimed to measure reflexive cough strength by cough peak flow (CPF) induced by citric acid nebulization (2.8 mol/L), record diaphragm excursions during reflexive coughs in stroke subjects at risk of silent aspiration, and compare these values with those of stroke subjects without risk of aspiration or dysphagia...
September 12, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28898547/hlx-is-a-candidate-gene-for-a-pattern-of-anomalies-associated-with-congenital-diaphragmatic-hernia-short-bowel-and-asplenia
#20
Sandra A Farrell, Sandi Sodhi, Christian R Marshall, Andrea Guerin, Anne Slavotinek, Tara Paton, Karen Chong, Wilma L Sirkin, Stephen W Scherer, Félix-Antoine Bérubé-Simard, Nicolas Pilon
Isolated congenital diaphragmatic hernia is often a sporadic event with a low recurrence risk. However, underlying genetic etiologies, such as chromosome anomalies or single gene disorders, are identified in a small number of individuals. We describe two fetuses with a unique pattern of multiple congenital anomalies, including diaphragmatic hernia, short bowel and asplenia, born to first-cousin parents. Whole exome sequencing showed that both were homozygous for a missense variant, c.950A>C, predicting p...
September 12, 2017: American Journal of Medical Genetics. Part A
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