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https://www.readbyqxmd.com/read/28548646/prevalence-and-the-risk-factors-for-visual-impairment-in-age-related-macular-degeneration
#1
S Srinivasan, G Swaminathan, V Kulothungan, R Raman, T Sharma
PurposeTo characterize the type, and the causes of visual impairment (VI) in various stages of early and late age-related macular degeneration (AMD) and the factors associated with visual impairment in subjects with AMDMethods6617 subjects ≥60 years were enumerated; 5495 (83.04%) participated in eye examination. Of which, 4791 subjects had gradable fundus images. AMD was graded per International ARM Epidemiological Study Group. Subjects underwent detailed ophthalmic exam. VI was defined per the WHO classification...
May 26, 2017: Eye
https://www.readbyqxmd.com/read/28511403/a-prospective-analysis-of-drug-interactions-in-patients-of-intensive-cardiac-care-unit
#2
Shipra Jain, Pushpawati Jain, Kopal Sharma, Pushpendra Saraswat
INTRODUCTION: Drug-Drug Interaction (DDI) is a serious concern in cardiac patients due to polypharmacy. AIM: The present study was aimed to identify the potential DDI among hospitalized cardiac patients and evaluate the mechanism and severity of such interactions. MATERIALS AND METHODS: A prospective observational study was conducted in intensive cardiac care unit of a tertiary care hospital for six months. Patients aged 18 years and above and taking two or more drugs were included in the study...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28403861/cardiac-shock-wave-therapy-in-the-treatment-of-coronary-artery-disease-systematic-review-and-meta-analysis
#3
REVIEW
Greta Burneikaitė, Evgeny Shkolnik, Jelena Čelutkienė, Gitana Zuozienė, Irena Butkuvienė, Birutė Petrauskienė, Pranas Šerpytis, Aleksandras Laucevičius, Amir Lerman
AIM: To systematically review currently available cardiac shock-wave therapy (CSWT) studies in humans and perform meta-analysis regarding anti-anginal efficacy of CSWT. METHODS: The Cochrane Controlled Trials Register, Medline, Medscape, Research Gate, Science Direct, and Web of Science databases were explored. In total 39 studies evaluating the efficacy of CSWT in patients with stable angina were identified including single arm, non- and randomized trials. Information on study design, subject's characteristics, clinical data and endpoints were obtained...
April 12, 2017: Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28387769/-99-tc-m-octreotide-scintigraphy-and-serum-eye-muscle-antibodies-in-evaluation-of-active-thyroid-associated-ophthalmopathy
#4
B Sun, Z Zhang, C Dong, Y Zhang, C Yan, S Li
PurposeAs an autoimmune inflammatory disorder, active thyroid-associated ophthalmopathy (TAO) is managed optimally by immunosuppression. In this study, we aimed to evaluate octreotide scintigraphy and the level of serum extraocular muscle antibodies in TAO activity.Patients and methodsThis prospective study comprised 304 patients with active TAO (the clinical activity score; CAS≥3), 73 with inactive TAO (CAS<3), 128 with Graves' disease (GD) without ophthalmopathy, and 100 healthy subjects. Moderate-to-severe active TAO patients (CAS≥5) received intravenous injection of methylprednisolone; mild active patients (3≤CAS≤4) received periocular injection of triamcinolone acetonide...
May 2017: Eye
https://www.readbyqxmd.com/read/28370697/-selecting-appraising-recommending-and-using-mobile-applications-apps-in-nursing
#5
EDITORIAL
Caleb Ferguson, Debra Jackson
It's more than likely that a patient, their family member or a colleague may have recently asked you "Is there an app for that?" Mobile technology is inescapable. It is pervasive in almost every aspect of daily life. Wherever we look, people are often hunched over and fully immersed by a small 6 x 3 inch screen, whether it be walking on the street, travelling on the bus, at the coffee shop or in the clinic waiting room. Mobile devices have infiltrated most aspects of our lives and offer quick, adaptive tech-based solutions to many previously administrative, repetitive or otherwise time-consuming tasks...
March 31, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28338667/primary-photodynamic-therapy-with-verteporfin-for-small-pigmented-posterior-pole-choroidal-melanoma
#6
I D Fabian, A W Stacey, V Papastefanou, L Al Harby, A K Arora, M S Sagoo, V M L Cohen
PurposeThe purpose of the study was to investigate the outcomes of primary photodynamic therapy (PDT) for small pigmented posterior pole choroidal melanoma.Patients and methodsProspective interventional consecutive case series of 15 patients with small pigmented posterior pole choroidal melanoma, who were treated with three sessions of PDT and followed-up thereafter. Risk factors for failure were assessed and outcome measures at presentation were compared to those at last follow-up visit.ResultsTumor control was achieved in 12 (80%) patients in a median follow-up time of 15 months (mean 14, range 8-18)...
April 2017: Eye
https://www.readbyqxmd.com/read/28322678/staying-afloat-in-a-sea-of-information-point-of-care-resources
#7
REVIEW
Rebecca Andrews, Neil Mehta, Jack Maypole, Stephen A Martin
Physicians can use a variety of electronic resources at the point of care to help them make decisions about patient management. The authors address the need for these resources, characterize the elements of good resources, and compare several popular ones, ie, Clinical Evidence, Dynamed, Evidence Essentials, First Consult, Medscape, and UpToDate.
March 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28286821/smartphones-and-medical-applications-in-the-emergency-department-daily-practice
#8
Amirhosein Jahanshir, Ehsan Karimialavijeh, Hojjat Sheikh, Motahar Vahedi, Mehdi Momeni
INTRODUCTION: Medical applications help physicians to make more rapid and evidence based decisions that may provide better patient care. This study aimed to determine the extent to which smart phones and medical applications are integrated in the emergency department daily practice. METHOD: In a cross sectional study, a modified standard questionnaire (Payne et al.) consisting of demographic data and information regarding quality and quantity of smartphone and medical app utilization was sent to emergency-medicine residents and interns twice (two weeks apart), in January 2015...
2017: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/28216952/risk-factors-for-developing-drug-related-problems-in-patients-with-cardiovascular-diseases-attending-gondar-university-hospital-ethiopia
#9
Ousman Abubeker Abdela, Akshaya Srikanth Bhagavathula, Henok Getachew, Yohannes Kelifa
BACKGROUND: Cardiovascular diseases (CVDs) are often accompanied with comoribidities and complications leading to taking multiple drugs and thus are more liable to be exposed to drug-related problems (DRPs). DRPs can occur at any stages of medication process from prescription to follow-up treatment. However, a few studies have assessed the specific risk factors for occurrence of at least one potential DRP per patient with CVDs in sub-Saharan African region. AIM: We aim to assess the risk factors for developing potential DRPs in patients with CVDs attending Gondar University Referral Hospital (GUH)...
October 2016: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28128798/prevalence-of-referable-sight-threatening-retinopathy-in-type-1-diabetes-and-its-relationship-to-diabetes-duration-and-systemic-risk-factors
#10
A N Warwick, A P Brooks, C Osmond, R Krishnan
PurposeThe purpose of the study was to provide contemporary estimates for diabetic retinopathy (DR) prevalence in a well-defined UK cohort of patients with type 1 diabetes (T1DM) and investigate potential risk factors for proliferative diabetic retinopathy (PDR) and diabetic maculopathy.Patients and MethodsFour hundred and sixty four T1DM patients in North Hampshire had T1DM duration, demographic and systemic risk factor data evaluated retrospectively alongside their DR status in 2010 using logistic regression analysis...
February 2017: Eye
https://www.readbyqxmd.com/read/28075650/pharmacokinetic-evaluation-of-pregabalin-for-the-treatment-of-generalized-anxiety-disorder
#11
REVIEW
Massimiliano Buoli, Alice Caldiroli, Marta Serati
Pregabalin is an alternative compound to SSRIs and SNRIs for the first-line treatment of generalized anxiety disorder (GAD). Areas covered: We describe the pharmacokinetic properties of pregabalin and their implications for the treatment of GAD. A search in the main database sources (Medline, ISI, Web of Knowledge and Medscape) was performed in order to obtain a comprehensive and balanced evaluation about the clinical implications of the pharmacokinetic properties of pregabalin in the treatment of GAD. The word "pregabalin" was associated with "pharmacokinetics", "interactions"', "GAD", "anxiety" and "tolerability"...
March 2017: Expert Opinion on Drug Metabolism & Toxicology
https://www.readbyqxmd.com/read/28018756/incidence-of-potential-drug-drug-interactions-in-a-limited-and-stereotyped-prescription-setting-comparison-of-two-free-online-pharmacopoeias
#12
Bhaskar Kannan, Amrutha Bindu Nagella, A Sathia Prabhu, Gopalakrishnan M Sasidharan, A S Ramesh, Venkatesh Madhugiri
BACKGROUND: Drug-drug interactions (DDIs) are very common adverse events in health care delivery settings. The use of electronic pharmacopeias can potentially reduce the incidence of DDIs, but they are often thought to be cumbersome to use. This study is aimed at studying the incidence of potential DDIs in a surgical department, where a limited number of drugs are used in stereotyped combinations. We also compared two popular drug compendia in detecting potential DDIs. METHODS: The prescriptions of selected patients were entered into Epocrates® and Medscape® for Android smartphones...
November 22, 2016: Curēus
https://www.readbyqxmd.com/read/28010895/platelet-derived-growth-factor-receptors-pdgfrs-fusion-genes-involvement-in-hematological-malignancies
#13
REVIEW
Kwaku Appiah-Kubi, Ting Lan, Ying Wang, Hai Qian, Min Wu, Xiaoyuan Yao, Yan Wu, Yongchang Chen
PURPOSE: To investigate oncogenic platelet-derived growth factor receptor(PDGFR) fusion genes involvement in hematological malignancies, the advances in the PDGFR fusion genes diagnosis and development of PDGFR fusions inhibitors. METHODS: Literature search was done using terms "PDGFR and Fusion" or "PDGFR and Myeloid neoplasm" or 'PDGFR and Lymphoid neoplasm' or "PDGFR Fusion Diagnosis" or "PDGFR Fusion Targets" in databases including PubMed, ASCO.org, and Medscape...
January 2017: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/27983728/safety-and-acceptability-of-an-organic-light-emitting-diode-sleep-mask-as-a-potential-therapy-for-retinal-disease
#14
J N Sahni, G Czanner, T Gutu, S A Taylor, K M Bennett, S M Wuerger, I Grierson, C Murray-Dunning, M N Holland, S P Harding
PurposeThe purpose of the study was to study the effect of an organic light-emitting diode sleep mask on daytime alertness, wellbeing, and retinal structure/function in healthy volunteers and in diabetic macular oedema (DMO).Patients and methodsHealthy volunteers in two groups, 18-30 yrs (A), 50-70 yrs (B) and people with DMO (C) wore masks (504 nm wavelength; 80 cd/m(2) luminance; ≤8 h) nightly for 3 months followed by a 1-month recovery period. Changes from baseline were measured for (means): psychomotor vigilance task (PVT) (number of lapses (NL), response time (RT)), sleep, depression, psychological wellbeing (PW), visual acuity, contrast sensitivity, colour, electrophysiology, microperimetry, and retinal thickness on OCT...
January 2017: Eye
https://www.readbyqxmd.com/read/27933638/nursing-interventions-for-smoking-cessation-in-hospitalized-patients-a-systematic-review
#15
REVIEW
Z Kazemzadeh, Z S Manzari, Z Pouresmail
AIM: This study aimed to clarify the role of nurses in planning and implementation of nursing interventions related to smoking cessation. BACKGROUND AND INTRODUCTION: Nearly half of all smokers die from smoking-related illnesses. Quitting smoking can reduce these problems. Smoking cessation interventions include various types helping smokers successfully quit. Studies suggest that hospitalization can be a golden opportunity for nurses helping patients to quit smoking because of No Smoking regulations...
June 2017: International Nursing Review
https://www.readbyqxmd.com/read/27882520/app-use-in-psychiatric-education-a-medical-student-survey
#16
Cecilia Lau, Venkata Kolli
OBJECTIVE: The objective of the study is to understand and appraise app use by medical students during their clerkships. METHODS: Following Creighton University IRB approval, a voluntary and anonymous paper-based, 15-question survey was distributed to third-year medical students. Data were analyzed using Microsoft Excel. RESULTS: Of 112 medical students available, 76.7% (86) participated in the survey. All participants owned a smartphone or tablet with 84...
February 2017: Academic Psychiatry
https://www.readbyqxmd.com/read/27858937/intravitreal-dexamethasone-implant-for-recurrent-cystoid-macular-edema-due-to-irvine-gass-syndrome-a-prospective-case-series
#17
A Sudhalkar, J Chhablani, A Vasavada, D Bhojwani, V Vasavada, S Vasavada
PurposeTo determine the preliminary efficacy and safety of off-label dexamethasone implant for treatment of recurrent cystoid macular edema (CME) secondary to Irvine-Gass syndrome (IGS).Patients and methodsThis study was set in Raghudeep Eye Clinic, Ahmedabad and LV Prasad Eye Institute, Hyderabad (India). It is a Prospective Case Series. Prospective case series comprising of patients with uncomplicated pseudophakia and CME due to IGS who recurred after one course of topical steroids with NSAIDS and a sub-Tenon corticosteroid injection...
December 2016: Eye
https://www.readbyqxmd.com/read/27843962/a-comparison-of-five-common-drug-drug-interaction-software-programs-regarding-accuracy-and-comprehensiveness
#18
Raziyeh Kheshti, Mohammadsadegh Aalipour, Soha Namazi
OBJECTIVE: Drug-drug interactions (DDIs) can cause failure in treatment and adverse events. DDIs screening software is an important tool to aid clinicians in the detection and management of DDIs. However, clinicians should be aware of the advantages and limitations of these programs. We compared the ability of five common DDI programs to detect clinically important DDIs. METHODS: Lexi-Interact, Micromedex Drug Interactions, iFacts, Medscape, and Epocrates were evaluated...
October 2016: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/27843792/a-study-of-medication-errors-in-a-tertiary-care-hospital
#19
Nrupal Patel, Mira Desai, Samdih Shah, Prakruti Patel, Anuradha Gandhi
OBJECTIVE: To determine the nature and types of medication errors (MEs), to evaluate occurrence of drug-drug interactions (DDIs), and assess rationality of prescription orders in a tertiary care teaching hospital. MATERIALS AND METHODS: A prospective, observational study was conducted in General Medicine and Pediatric ward of Civil Hospital, Ahmedabad during October 2012 to January 2014. MEs were categorized as prescription error, dispensing error, and administration error (AE)...
October 2016: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/27740618/the-effect-of-music-with-and-without-binaural-beat-audio-on-operative-anxiety-in-patients-undergoing-cataract-surgery-a-randomized-controlled-trial
#20
D Wiwatwongwana, P Vichitvejpaisal, L Thaikruea, J Klaphajone, A Tantong, A Wiwatwongwana
PurposeTo investigate the anxiolytic effects of binaural beat embedded audio in patients undergoing cataract surgery under local anesthesia.MethodsThis prospective RCT included 141 patients undergoing cataract surgery under local anesthesia. The patients were randomized into three groups; the Binaural beat music group (BB), the plain music intervention group (MI), and a control group (ear phones with no music). Blood pressure (BP) and heart rate were measured on admission, at the beginning of and 20 min after the start of the operation...
November 2016: Eye
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