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Vitamin D in pregnancy

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https://www.readbyqxmd.com/read/28333357/dietary-patterns-foods-and-nutrients-in-male-fertility-parameters-and-fecundability-a-systematic-review-of-observational-studies
#1
Albert Salas-Huetos, Mònica Bulló, Jordi Salas-Salvadó
BACKGROUND: Infertility is a global public health issue, affecting 15% of all couples of reproductive age. Male factors, including decreased semen quality, are responsible for ~25% of these cases. The dietary pattern, the components of the diet and nutrients have been studied as possible determinants of sperm function and/or fertility. OBJECTIVE AND RATIONALE: Previous systematic reviews have been made of the few heterogeneous low-quality randomized clinical trials (RCTs) conducted in small samples of participants and investigating the effect of specific nutrients and nutritional supplements on male infertility...
March 10, 2017: Human Reproduction Update
https://www.readbyqxmd.com/read/28331572/environmental-risk-factors-for-autism-an-evidence-based-review-of-systematic-reviews-and-meta-analyses
#2
REVIEW
Amirhossein Modabbernia, Eva Velthorst, Abraham Reichenberg
BACKGROUND: According to recent evidence, up to 40-50% of variance in autism spectrum disorder (ASD) liability might be determined by environmental factors. In the present paper, we conducted a review of systematic reviews and meta-analyses of environmental risk factors for ASD. We assessed each review for quality of evidence and provided a brief overview of putative mechanisms of environmental risk factors for ASD. FINDINGS: Current evidence suggests that several environmental factors including vaccination, maternal smoking, thimerosal exposure, and most likely assisted reproductive technologies are unrelated to risk of ASD...
2017: Molecular Autism
https://www.readbyqxmd.com/read/28320597/racial-or-ethnic-and-socioeconomic-inequalities-in-adherence-to-national-dietary-guidance-in-a-large-cohort-of-us-pregnant-women
#3
Lisa M Bodnar, Hyagriv N Simhan, Corette B Parker, Heather Meier, Brian M Mercer, William A Grobman, David M Haas, Deborah A Wing, Matthew K Hoffman, Samuel Parry, Robert M Silver, George R Saade, Ronald Wapner, Jay D Iams, Pathik D Wadhwa, Michal Elovitz, Alan M Peaceman, Sean Esplin, Shannon Barnes, Uma M Reddy
BACKGROUND: The significance of periconceptional nutrition for optimizing offspring and maternal health and reducing social inequalities warrants greater understanding of diet quality among US women. OBJECTIVE: Our objective was to evaluate racial or ethnic and education inequalities in periconceptional diet quality and sources of energy and micronutrients. DESIGN: Cross-sectional analysis of data from the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be cohort...
March 14, 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28320484/nutritional-intervention-preconception-and-during-pregnancy-to-maintain-healthy-glucose-metabolism-and-offspring-health-nipper-study-protocol-for-a-randomised-controlled-trial
#4
Keith M Godfrey, Wayne Cutfield, Shiao-Yng Chan, Philip N Baker, Yap-Seng Chong
BACKGROUND: Improved maternal nutrition and glycaemic control before and during pregnancy are thought to benefit the health of the mother, with consequent benefits for infant body composition and later obesity risk. Maternal insulin resistance and glycaemia around conception and in early pregnancy may be key determinants of maternal physiology and placental function, affecting fetal nutrient supply and maternal-feto-placental communications throughout gestation, with implications for later postnatal health...
March 20, 2017: Trials
https://www.readbyqxmd.com/read/28316773/vitamin-d-treatment-during-pregnancy-prevents-autism-related-phenotypes-in-a-mouse-model-of-maternal-immune-activation
#5
Stephanie Vuillermot, Wei Luan, Urs Meyer, Darryl Eyles
BACKGROUND: Prenatal exposure to infection is a recognized environmental risk factor for neuropsychiatric disorders of developmental origins such as autism or schizophrenia. Experimental work in animals indicates that this link is mediated by maternal immune activation (MIA) involving interactions between cytokine-associated inflammatory events, oxidative stress, and other pathophysiological processes such as hypoferremia and zinc deficiency. Maternal administration of the viral mimic polyriboinosinic-polyribocytidylic acid (poly(I:C)) in mice produces several behavioral phenotypes in adult offspring of relevance to autism spectrum disorder (ASD) and other neurodevelopmental disorders...
2017: Molecular Autism
https://www.readbyqxmd.com/read/28306725/maternal-vitamin-d-insufficiency-and-risk-of-adverse-pregnancy-and-birth-outcomes-a-systematic-review-and-meta-analysis-of-longitudinal-studies
#6
A Kofi Amegah, Moses K Klevor, Carol L Wagner
BACKGROUND: Three previous reviews on the association of vitamin D insufficiency in pregnancy with preterm birth (PTB) and stillbirth were limited in scope and deemed inconclusive. With important new evidence accumulating, there is the need to update the previous estimates and assess evidence on other clinically important outcomes such as spontaneous abortion and Apgar score. We conducted a systematic review and meta-analysis to evaluate the quality and strength of the available evidence on the relations between vitamin D nutritional status, and pregnancy and birth outcomes...
2017: PloS One
https://www.readbyqxmd.com/read/28291591/the-inma-infancia-y-medio-ambiente-environment-and-childhood-project-more-than-10-years-contributing-to-environmental-and-neuropsychological-research
#7
REVIEW
Mireia Gascon, Mònica Guxens, Martine Vrijheid, Maties Torrent, Jesús Ibarluzea, Eduardo Fano, Sabrina Llop, Ferran Ballester, Mariana F Fernández, Adonina Tardón, Ana Fernández-Somoano, Jordi Sunyer
BACKGROUND: In 2003 the INMA-INfancia y Medio Ambiente (Environment and Childhood) project, a Spanish national network of birth cohorts including more than 3500 participants, was set up with the aim to assess the health impacts of pre- and postnatal environmental exposures on children. The project has published more than 60 papers on maternal and environmental factors related to neuropsychological development in children, one of the main research interests within the project. With the present review, we evaluate the evidence provided by the INMA project on this topic and discuss how the data can contribute to cover the challenges that children's environmental health research will face in the coming years...
February 28, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28287490/correlations-between-maternal-breast-milk-and-infant-vitamin-b12-concentrations-among-mother-infant-dyads-in-vancouver-canada-and-prey-veng-cambodia-an-exploratory-analysis
#8
Philip Chebaya, Crystal D Karakochuk, Kaitlin M March, Nancy N Chen, Rosemary A Stamm, Hou Kroeun, Prak Sophonneary, Mam Borath, Setareh Shahab-Ferdows, Daniela Hampel, Susan I Barr, Yvonne Lamers, Lisa A Houghton, Lindsay H Allen, Tim J Green, Kyly C Whitfield
Vitamin B12 plays an essential role in fetal and infant development. In regions where animal source food consumption is low and perinatal supplementation is uncommon, infants are at risk of vitamin B12 deficiency. In this secondary analysis, we measured total vitamin B12 concentrations in maternal and infant serum/plasma and breast milk among two samples of mother-infant dyads in Canada (assessed at 8 weeks post-partum) and in Cambodia (assessed between 3-27 weeks post-partum). Canadian mothers (n = 124) consumed a daily vitamin B12-containing multiple micronutrient supplement throughout pregnancy and lactation; Cambodian mothers (n = 69) were unsupplemented...
March 12, 2017: Nutrients
https://www.readbyqxmd.com/read/28287422/prevalence-of-vitamin-d-deficiency-and-its-associations-with-skin-color-in-pregnant-women-in-the-first-trimester-in-a-sample-from-switzerland
#9
Aline Richard, Sabine Rohrmann, Katharina C Quack Lötscher
Vitamin D deficiency in pregnancy has negative clinical consequences, such as associations with glucose intolerance, and has been shown to be distributed differently in certain ethnic groups. In some countries, a difference in the rate of vitamin D deficiency was detected in pregnant women depending on their skin color. We examined the prevalence of vitamin D deficiency (<20 ng/mL) in women in early pregnancy in Switzerland and evaluated the association of skin color with vitamin D deficiency. In a single-center cohort study, the validated Fitzpatrick scale and objective melanin index were used to determine skin color...
March 10, 2017: Nutrients
https://www.readbyqxmd.com/read/28285844/vitamin-d-supplementation-in-pregnancy-prenatal-25-oh-d-levels-race-and-subsequent-asthma-or-recurrent-wheeze-in-offspring-secondary-analyses-from-the-vitamin-d-antenatal-asthma-reduction-trial
#10
Helene M Wolsk, Benjamin J Harshfield, Nancy Laranjo, Vincent J Carey, George O'Connor, Megan Sandel, Robert C Strunk, Leonard B Bacharier, Robert S Zeiger, Michael Schatz, Bruce W Hollis, Scott T Weiss, Augusto A Litonjua
BACKGROUND: Nutrient trials differ from drug trials because participants have varying circulating levels at entry into the trial. OBJECTIVE: We sought to study the effect of a vitamin D intervention in pregnancy between subjects of different races and the association between 25-hydroxyvitamin D3 (25[OH]D) levels in pregnancy and the risk of asthma/recurrent wheeze in offspring. METHODS: The Vitamin D Antenatal Asthma Reduction Trial is a randomized trial of pregnant women at risk of having children with asthma randomized to 4400 international units/d vitamin D or placebo plus 400 international units/d vitamin D...
March 9, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28275100/maternal-supplementation-with-small-quantity-lipid-based-nutrient-supplements-compared-with-multiple-micronutrients-but-not-with-iron-and-folic-acid-reduces-the-prevalence-of-low-gestational-weight-gain-in-semi-urban-ghana-a-randomized-controlled-trial
#11
Seth Adu-Afarwuah, Anna Lartey, Harriet Okronipa, Per Ashorn, Ulla Ashorn, Mamane Zeilani, Mary Arimond, Stephen A Vosti, Kathryn G Dewey
Background: It is unclear whether maternal supplementation with small-quantity lipid-based nutrient supplements (SQ-LNSs; 118 kcal/d) affects maternal weight.Objective: We compared several secondary anthropometric measures between 3 groups of women in the iLiNS (International Lipid-based Nutrient Supplements)-DYAD trial in Ghana.Methods: Women (n = 1320; <20 wk of gestation) were randomly assigned to receive 60 mg Fe + 400 μg folic acid/d (IFA), 18 vitamins and minerals/d [multiple micronutrients (MMNs)], or 20 g SQ-LNSs with 22 micronutrients/d (LNS) during pregnancy and a placebo (200 mg Ca/d), MMNs, or SQ-LNSs, respectively, for 6 mo postpartum...
March 8, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28264782/pregnancy-outcome-and-ultraviolet-radiation-a-systematic-review
#12
REVIEW
Lauren Megaw, Tom Clemens, Chris Dibben, Richard Weller, Sarah Stock
BACKGROUND: Season and vitamin D are indirect and direct correlates of ultraviolet (UV) radiation and are associated with pregnancy outcomes. Further to producing vitamin D, UV has positive effects on cardiovascular and immune health that may support a role for UV directly benefitting pregnancy. OBJECTIVES: To investigate the effects of UV exposure on pregnancy; specifically fetal growth, preterm birth and hypertensive complications. METHODS: We conducted a systematic review of Medline, EMBASE, DoPHER, Global Health, ProQuest Public Health, AustHealth Informit, SCOPUS and Google Scholar to identify 537 citations, 8 of which are included in this review...
March 3, 2017: Environmental Research
https://www.readbyqxmd.com/read/28255653/season-dietary-factors-and-physical-activity-modify-25-hydroxyvitamin-d-concentration-during-pregnancy
#13
Helena H Hauta-Alus, Elisa M Holmlund-Suila, Hannu J Rita, Maria Enlund-Cerullo, Jenni Rosendahl, Saara M Valkama, Otto M Helve, Timo K Hytinantti, Heljä-Marja Surcel, Outi M Mäkitie, Sture Andersson, Heli T Viljakainen
PURPOSE: The objectives of this cross-sectional study were to define maternal and umbilical cord blood (UCB) 25-hydroxyvitamin D (25(OH)D) to characterize maternal factors modifying 25(OH)D during pregnancy and predict UCB 25(OH)D in two subgroups with Declined [Δ25(OH)D <0 nmol/l] and Increased [Δ25(OH)D >0 nmol/l] 25(OH)D concentration. METHODS: A complete dataset was available from 584 women. 25(OH)D was determined at gestational weeks 6-13 and in UCB...
March 2, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28249640/maternal-use-of-dietary-supplements-during-pregnancy-is-not-associated-with-coeliac-disease-in-the-offspring-the-environmental-determinants-of-diabetes-in-the-young-teddy-study
#14
Jimin Yang, Roy N Tamura, Carin A Aronsson, Ulla M Uusitalo, Åke Lernmark, Marian Rewers, William A Hagopian, Jin-Xiong She, Jorma Toppari, Anette G Ziegler, Beena Akolkar, Jeffrey P Krischer, Jill M Norris, Suvi M Virtanen, Daniel Agardh
Perinatal exposure to nutrients and dietary components may affect the risk for coeliac disease (CD). We investigated the association between maternal use of vitamin D, n-3 fatty acids (FA) and Fe supplements during pregnancy and risk for CD autoimmunity (CDA) and CD in the offspring. Children at increased genetic risk were prospectively followed from birth in The Environmental Determinants of Diabetes in the Young (TEDDY) study. CDA was defined as having persistently positive tissue transglutaminase autoantibodies (tTGA)...
March 2, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28245457/steroids-and-autoimmunity
#15
Amelia Chiara Trombetta, Marianna Meroni, Maurizio Cutolo
From the middle of the 19th century, it is known that endocrine and immune systems interact bi-directionally in different processes that ensure organism homeostasis. Endocrine and nervous systems have a pivotal role in the balancing of pro- and anti-inflammatory functions of immune system, and constitute a complex circadian neuroendocrine network. Autoimmune diseases have in fact a complex pathogenic origin in which the importance of endocrine system was demonstrated. In this chapter, we will mention the structure and function of steroidal hormones involved in the neuroendocrine immune network and we will address the ways in which endocrine and immune systems influence each other, in a bi-directional fashion...
2017: Frontiers of Hormone Research
https://www.readbyqxmd.com/read/28244707/serum-25-hydroxyvitamin-d-in-pregnant-women-during-preterm-labor
#16
Nalina Bhupornvivat, Vorapong Phupong
BACKGROUND AND OBJECTIVES: Pregnancy complications hypothesized to be related to vitamin D include preeclampsia, gestational diabetes, low birth weight, preterm delivery, Cesarean section and infectious disease. There have been a few studies which have demonstrated maternal serum vitamin D to be associated with preterm labor. The objective was to evaluate the serum vitamin D concentrations in Thai pregnant women with and without preterm labor and to find the prevalence of vitamin D deficiency and insufficiency in both groups...
March 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28244294/vitamin-d-and-urinary-incontinence-among-korean-women-a-propensity-score-matched-analysis-from-the-2008-2009-korean-national-health-and-nutrition-examination-survey
#17
Hyo Serk Lee, Jun Ho Lee
A recent study investigated the role of vitamin D in urinary incontinence (UI). However, very few data are available on this topic. Therefore, we evaluated these relationships using nationally representative data from Korea. We included 6,451 women over the age of 20 years who had participated in the Korea National Health and Nutrition Examination Survey IV. We conducted a propensity-matched study by identifying women with UI. Women without UI, matched for menopause, number of pregnancies, hypertension, diabetes, body mass index, age, stroke, asthma, and chronic obstructive pulmonary disease, were selected as a control group at a 2:1 ratio...
April 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28241988/effects-of-maternal-genetic-polymorphisms-in-vitamin-d-binding-protein-and-serum-25-hydroxyvitamin-d-concentration-on-infant-birth-weight
#18
Soo-Kyung Chun, Sangah Shin, Moon Young Kim, Hyojee Joung, Jayong Chung
OBJECTIVE: Vitamin D deficiency is a common problem during pregnancy and might contribute to adverse birth outcomes. Vitamin D-binding protein plays a key role in regulating vitamin D metabolism. We investigated whether maternal genetic variation in GC, the gene encoding vitamin-D binding protein, modulates the relationship between 25-hydroxyvitamin D [25(OH)D] levels and infant birth weight. METHODS: We measured 25(OH)D concentrations in maternal and umbilical cord blood from 356 pregnant women and their infants by liquid chromatography tandem mass spectrometry...
March 2017: Nutrition
https://www.readbyqxmd.com/read/28236844/altered-metabolic-homeostasis-between-vitamin-d-and-long-chain-polyunsaturated-fatty-acids-in-preeclampsia
#19
Anindita A Nandi, Nisha S Wadhwani, Sadhana R Joshi
Sub-optimal maternal nutrition may result in pregnancy complications like preeclampsia. Preeclampsia is known to be of placental origin and a major cause of maternal morbidity and mortality worldwide. Our earlier studies suggest that altered metabolism of folic acid, vitamin B12 and long chain polyunsaturated fatty acid (LCPUFAs) in the one carbon cycle increases homocysteine levels in preeclampsia. Recent reports indicate that vitamin D deficiency may also have a role in preeclampsia, although the mechanisms are unclear...
March 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28228790/successful-neridronate-therapy-in-pregnancy-associated-osteoporosis
#20
Agostino Gaudio, Carmelo Erio Fiore
Pregnancy-associated osteoporosis is a rare condition. The pathogenesis is probably multifactorial but has not yet been completely clarified. In this case report, a 38-year-old woman was referred to hospital after suffering an acute, non-traumatic back pain one month after delivering her first child. The radiological examination revealed four vertebral fractures. Bone mineral density was reduced, particularly at spine level. Biochemical tests were within normal range, except for increased urinary deoxypyridinoline and a slight reduction of the serum 25-OH vitamin D level...
September 2016: Clinical Cases in Mineral and Bone Metabolism
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