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https://www.readbyqxmd.com/read/28904810/nasal-high-flow-treatment-in-preterm-infants
#1
REVIEW
Calum T Roberts, Kate A Hodgson
Nasal High Flow (HF) is a mode of 'non-invasive' respiratory support for preterm infants, with several potential modes of action, including generation of distending airway pressure, washout of the nasopharyngeal dead space, reduction of work of breathing, and heating and humidification of inspired gas. HF has several potential advantages over continuous positive airway pressure (CPAP), the most commonly applied form of non-invasive support, such as reduced nasal trauma, ease of use, and infant comfort, which has led to its rapid adoption into neonatal care...
2017: Maternal Health, Neonatology and Perinatology
https://www.readbyqxmd.com/read/28901997/risk-factors-associated-with-intraventricular-hemorrhage-in-extremely-premature-neonates
#2
Jonathan C Roberts, M Jawad Javed, James R Hocker, Huaping Wang, Michael D Tarantino
: Intraventricular hemorrhage (IVH) is a significant cause of morbidity in extremely premature infants despite many advances in neonatal intensive care. We conducted an institutional retrospective review aimed to correlate risk factors associated with IVH. Clinical variables reported to the Vermont-Oxford Network on less than 30 weeks gestational age infants over a 5-year period were evaluated with Pearson's chi-square and multivariate logistic regression. Of 618 infants born less than 30-week gestational age, 178 (28...
September 8, 2017: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/28890836/new-diagnosis-of-aids-based-on-salmonella-enterica-subsp-i-enterica-enteritidis-a-meningitis-in-a-previously-immunocompetent-adult-in-the-united-states
#3
Andrew C Elton, James Levin, Matthew P Lazio
Salmonella meningitis is a rare manifestation of meningitis typically presenting in neonates and the elderly. This infection typically associates with foodborne outbreaks in developing nations and AIDS-endemic regions. We report a case of a 19-year-old male presenting with altered mental status after 3-day absence from work at a Wisconsin tourist area. He was febrile, tachycardic, and tachypneic with a GCS of 8. The patient was intubated and a presumptive diagnosis of meningitis was made. Treatment was initiated with ceftriaxone, vancomycin, acyclovir, dexamethasone, and fluid resuscitation...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/28883098/randomised-trial-of-estimating-oral-endotracheal-tube-insertion-depth-in-newborns-using-weight-or-vocal-cord-guide
#4
Irwin Gill, Aisling Stafford, Madeleine C Murphy, Aisling R Geoghegan, Miranda Crealey, Eoghan Laffan, Colm Patrick Finbarr O'Donnell
BACKGROUND: When intubating newborns, clinicians aim to position the endotracheal tube (ETT) tip in the midtrachea. The depth to which ETTs should be inserted is often estimated using the infant's weight. ETTs are frequently incorrectly positioned in newborns, most often inserted too far. Using the vocal cord guide (a mark at the distal end of the ETT) to guide insertion depth has been recommended. OBJECTIVE: To determine whether estimating ETT insertion depth using the vocal cord guide rather than weight results in more correctly positioned ETT tips...
September 7, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28871620/oropharyngeal-surfactant-can-improve-initial-stabilisation-and-reduce-rescue-intubation-in-infants-born-below-25-weeks-of-gestation
#5
Tereza Lamberska, Eva Settelmayerova, Jan Smisek, Marketa Luksova, Gabriela Maloskova, Richard Plavka
AIM: Minimally aggressive and easily performed techniques that facilitate spontaneous respiratory stabilisation are required to reduce rescue intubation in extremely premature infants. This study evaluated the feasibility and safety of administering surfactant into the pharynx of infants born at less than 25 weeks immediately after birth. METHODS: This study of 19 infants was conducted from January 2013 to July 2014 in a tertiary perinatal centre in Prague. We administered 1...
September 4, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28866689/reply-to-the-letter-to-the-editor-does-remifentanil-have-a-place-for-sedation-in-the-case-of-endotracheal-intubation-or-minimally-invasive-surfactant-therapy-in-neonates
#6
Ellen H M de Kort, Sinno H P Simons
No abstract text is available yet for this article.
September 2, 2017: Neonatology
https://www.readbyqxmd.com/read/28866673/does-remifentanil-have-a-place-for-sedation-in-the-case-of-endotracheal-intubation-or-minimally-invasive-surfactant-therapy-in-neonates
#7
Clément Chollat, Fabien Tourrel, Stéphane Marret
No abstract text is available yet for this article.
September 2, 2017: Neonatology
https://www.readbyqxmd.com/read/28866624/severe-acquired-subglottic-stenosis-in-neonatal-intensive-care-graduates-a-case-control-study
#8
Rebecca E Thomas, Shripada C Rao, Corrado Minutillo, Shyan Vijayasekaran, Elizabeth A Nathan
OBJECTIVE: To analyse current incidence and risk factors associated with severe acquired subglottic stenosis (SASGS) requiring surgical intervention in neonates. DESIGN: Retrospective case-control study. SETTING: Sole tertiary children's hospital. PARTICIPANTS: Patients who underwent surgical intervention for SASGS from January 2006 to December 2014. For each neonatal intensive care unit (NICU) graduate with acquired SASGS, two controls were selected (matched for gestation and year of birth)...
September 2, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28833570/neural-breathing-pattern-in-newborn-infants-pre-and-postextubation
#9
Narayan P Iyer, John Dickson, Michelle E Ruiz, Robert Chatburn, Jennifer Beck, Chister Sinderby, Ricardo J Rodriguez
AIM: To describe the neural breathing pattern before and after extubation in newborn infants. METHODS: Prospective, observational study. In infants deemed ready for extubation, the diaphragm electrical activity (EAdi) was continuously recorded from 30 minute before to two hours after extubation. RESULTS: Total of 25 neonates underwent 29 extubations; 10 extubations resulted in re-intubation within 72 hours. Postextubation, there was an increase in peak EAdi (EAdi-max) and EAdi-delta (peak minus minimum EAdi) in both groups...
August 22, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28830746/risk-factors-and-molecular-epidemiology-of-acinetobacter-baumannii-bacteremia-in-neonates
#10
Hao-Yuan Lee, Shih-Yun Hsu, Jen-Fu Hsu, Chyi-Liang Chen, Yi-Hsin Wang, Cheng-Hsun Chiu
BACKGROUND: Acinetobacter baumannii infections in neonates are not uncommon but rarely studied. METHODS: Clinical and molecular epidemiology of 40 patients with A. baumannii bacteremia in the neonatal intensive care units (NICUs) of a medical center from 2004 to 2014 was analyzed. RESULTS: Multi-drug resistance was found in only 3 isolates (7.5%). Sequence types (STs) of A. baumannii defined by multilocus sequencing typing were diverse, and 72...
August 8, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28818854/nasal-midazolam-vs-ketamine-for-neonatal-intubation-in-the-delivery-room-a-randomised-trial
#11
Christophe Milési, Julien Baleine, Thibault Mura, Fernando Benito-Castro, Félicie Ferragu, Gérard Thiriez, Pierre Thévenot, Clémentine Combes, Ricardo Carbajal, Gilles Cambonie
OBJECTIVE: To compare the effectiveness of sedation by intranasal administration of midazolam (nMDZ) or ketamine (nKTM) for neonatal intubation. DESIGN: A multicentre, prospective, randomised, double-blind study. SETTING: Delivery rooms at four tertiary perinatal centres in France. PATIENTS: Preterm neonates with respiratory distress requiring non-emergent endotracheal intubation for surfactant instillation. INTERVENTIONS: Treatment was randomly allocated, with each neonate receiving a bolus of 0...
August 17, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28810610/microbial-investigations-in-throat-swab-and-tracheal-aspirate-specimens-are-beneficial-to-predict-the-corresponding-endotracheal-tube-biofilm-flora-among-intubated-neonates-with-ventilator-associated-pneumonia
#12
Yun Pan, Lizhong Du, Qing Ai, Sijie Song, Xiaoli Tang, Danping Zhu, Jialin Yu
Ventilator-associated pneumonia (VAP) is a common nosocomial infection in neonatal intensive care units with high morbidity and mortality. Bacterial biofilm in the endotracheal tube (ET) provides a notable and persistent source of pathogens that may cause VAP, and thus is important for VAP detection. However, during intubation microbial investigations in ET, samples are unavailable due to the infeasibility of collecting ET samples during intubation of neonates. It is therefore of great importance to find alternative sources of samples that can help identify the ET biofilm flora...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28805620/ex-utero-intrapartum-treatment-for-extremely-low-birth-weight-neonates-requiring-resuscitation-at-birth
#13
Tai-Ho Hung, Ting-Xuan Huang, T'sang-T'ang Hsieh
OBJECTIVE: Difficulties often encountered during intubation in extremely low birth-weight (ELBW) neonates requiring resuscitation at birth because of the smaller airway and the pressure from the limited number of attempts before hemodynamic instability occurs. CASE REPORT: We evaluated two pregnant women at 26 weeks of gestation with premature rupture of membranes and evidence of chorioamnionitis and applied the concept of ex utero intrapartum treatment, which involved delaying cord clamping (DCC) after establishing a secured airway with adequate ventilation during cesarean delivery...
August 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28803456/evaluation-of-prenatal-corticosteroid-use-in-spontaneous-preterm-labor-in-the-brazilian-multicenter-study-on-preterm-birth-emip
#14
Tabata Z Dias, Renato Passini, Ricardo P Tedesco, Giuliane J Lajos, Patricia M Rehder, Marcelo L Nomura, Maria L Costa, Paulo F Oliveira, Maria H Sousa, Jose G Cecatti
OBJECTIVE: To evaluate prenatal corticosteroid use in women experiencing spontaneous preterm labor and preterm delivery. METHODS: The present cross-sectional multicenter study analyzed interview data from patients attending 20 hospitals in Brazil owing to preterm delivery between April 1, 2011, and September 30, 2012. Patients were stratified based on preterm labor occurring before 34 weeks or at 34-36(+6) weeks of pregnancy, and the frequency of prenatal corticosteroid use at admission was compared...
August 13, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28802261/how-do-different-brands-of-size-1-laryngeal-mask-airway-compare-with-face-mask-ventilation-in-a-dedicated-laryngeal-mask-airway-teaching-manikin
#15
Mark Brian Tracy, Archana Priyadarshi, Dimple Goel, Krista Lowe, Jacqueline Huvanandana, Murray Hinder
BACKGROUND: International neonatal resuscitation guidelines recommend the use of laryngeal mask airway (LMA) with newborn infants (≥34 weeks' gestation or >2 kg weight) when bag-mask ventilation (BMV) or tracheal intubation is unsuccessful. Previous publications do not allow broad LMA device comparison. OBJECTIVE: To compare delivered ventilation of seven brands of size 1 LMA devices with two brands of face mask using self-inflating bag (SIB). DESIGN: 40 experienced neonatal staff provided inflation cycles using SIB with positive end expiratory pressure (PEEP) (5 cmH2O) to a specialised newborn/infant training manikin randomised for each LMA and face mask...
August 11, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28794088/ventilator-respiratory-graphic-diagnosis-of-hiccupping-in-non-ketotic-hyperglycinaemia
#16
Eliana Panayiotou, Kelly Spike, Colin Morley, Gusztav Belteki
A neonate presented with early encephalopathy deteriorated and was intubated and ventilated. Ventilator data were monitored and recorded at 100 Hz for 24 hours.The infant had many sudden deep inspirations during this time which were initially thought to be seizures. These were characterised by short, rapid, large inspirations when the airway pressure was reduced well below the positive end expiratory pressure level. Analysis of the ventilator data showed that these were hiccupping episodes misinterpreted by the ventilator as spontaneous breaths and triggering ventilator inflations...
August 9, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28768280/chest-compressions-during-sustained-inflations-improve-recovery-when-compared-to-a-3-1-compression-ventilation-ratio-during-cardiopulmonary-resuscitation-in-a-neonatal-porcine-model-of-asphyxia
#17
Elliott S Li, Immanuel Görens, Po-Yin Cheung, Tze-Fun Lee, Min Lu, Megan O'Reilly, Georg M Schmölzer
BACKGROUND: Recently, sustained inflations (SI) during chest compression (CC) (CC+SI) have been suggested as an alternative to the current approach during neonatal resuscitation. No previous study compared CC+SI using CC rates of 90/min to the current 3:1 compression:ventilation ratio (C:V). OBJECTIVE: To determine whether CC+SI versus a 3:1 C:V reduces the time to the return of spontaneous circulation (ROSC) and improves hemodynamic recovery in newborn piglets with asphyxia-induced bradycardia...
August 3, 2017: Neonatology
https://www.readbyqxmd.com/read/28740684/pediatric-airway-surgery
#18
REVIEW
Konrad Hoetzenecker, Thomas Schweiger, Doris Maria Denk-Linnert, Walter Klepetko
The management of pediatric airway pathology can be challenging and requires a dedicated team, consisting of thoracic surgeons, phoniatricians, logopedics, pediatricians and anesthetists. It necessitates a tailored treatment approach for each individual patient in order to address the minor variances that exist between cases. The majority of pediatric airway problems are a sequela of prematurity and prolonged post-partal intubation/tracheostomy. Surgical repair is often complicated by additional malformation or severe comorbidities...
June 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28734807/-a-survey-on-premedication-prior-to-intubation-in-very-preterm-infants-28-32wg-with-respiratory-distress-syndrome-in-french-neonatal-intensive-care-units
#19
E Boiron, E Merlot, G Loron, X Durrmeyer, E Guyot
INTRODUCTION/OBJECTIVES: Tracheal intubation is a painful procedure for which the routine use of analgesia is recommended. However, the use of premedication for intubation is not yet generalized and there is great diversity in the drugs used. The main objective of this study was to describe the frequency of premedication use in preterm neonates aged between 28 and 32weeks of gestation, intubated for respiratory distress syndrome. Secondary objectives were to describe the existence of a written protocol, its influence on the frequency of premedication and the drugs used...
July 19, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28734732/perinatal-and-neonatal-use-of-sedation-and-analgesia
#20
REVIEW
Christopher McPherson, Terrie Inder
Optimal obstetric and neonatal care requires the provision of adequate analgesia for painful procedures. However, anesthetic and analgesic agents have the potential to adversely impact the developing fetal/neonatal brain. In this setting, clinicians must assess the risks and benefits of pharmacologic anesthesia and analgesia for specific indications in this population. General anesthesia is required for non-obstetric surgery and cesarean section in the absence of neuraxial anesthesia for the health of the mother and fetus...
October 2017: Seminars in Fetal & Neonatal Medicine
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