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https://www.readbyqxmd.com/read/28725291/relationship-between-normal-tension-glaucoma-and-flammer-syndrome
#1
Katarzyna Konieczka, Hyuk Jin Choi, Simone Koch, Franz Fankhauser, Andreas Schoetzau, Dong Myung Kim
BACKGROUND: Besides intraocular pressure, vascular factors play a role in the pathogenesis of glaucomatous optic neuropathy. One of these potential vascular factors is Flammer syndrome. The purpose of the present study was to determine in a Korean population whether signs and symptoms of Flammer syndrome occur more often in normal tension glaucoma patients than in control subjects. METHODS: Two hundred forty-six normal tension glaucoma patients and 1116 control subjects responded to a multiple-choice questionnaire asking about 15 signs and symptoms of Flammer syndrome...
June 2017: EPMA Journal
https://www.readbyqxmd.com/read/28706987/influence-of-cold-ischemia-time-in-kidney-transplants-from-small-pediatric-donors
#2
Liise K Kayler, Michelle Lubetzky, Xia Yu, Patricia Friedmann
BACKGROUND: Clinicians may be reluctant to transplant small pediatric kidneys that have prolonged cold ischemia time (CIT) for fear of an additional deleterious effect because pediatric grafts are thought to be more sensitive to ischemia. We aimed to assess the risks associated with transplantation of small pediatric kidneys with prolonged CIT. METHODS: We performed a retrospective cohort study examining US registry data between 1998 and 2013 of adult first-time kidney-only recipients of small pediatric kidneys from donors weighing 10 to 20 kg, stratified by CIT levels of 0 to 18 (n = 1413), 19 to 30 (n = 1116), and longer than 30 (n = 338) hours...
July 2017: Transplantation Direct
https://www.readbyqxmd.com/read/28690005/pediatric-emergency-department-resource-utilization-among-children-with-primary-care-clinic-contact-in-the-preceding-2-days-a-cross-sectional-study
#3
Christina K Grech, Molly A Laux, Heather L Burrows, Michelle L Macy, Elaine S Pomeranz
OBJECTIVES: To characterize pediatric patient contacts with their primary care clinic in the 2 days preceding a visit to the emergency department (ED) and explore how the type of clinic contact relates to ED resource use. STUDY DESIGN: We conducted a retrospective chart review of 368 pediatric ED visits in the first 7 days of each month, from September 2012 to August 2013. Visits were included if the family contacted their child's general pediatric clinic in the study health system in the 2 days preceding the ED visit...
July 6, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28687182/consistency-of-priorities-for-quality-improvement-for-nursing-homes-in-italy-and-canada-a-comparison-of-optimization-models-of-resident-satisfaction
#4
REVIEW
Sara Barsanti, Kevin Walker, Chiara Seghieri, Antonella Rosa, Walter P Wodchis
The paper seeks to identify aspects of care that may be easily modified to yield a desired level of improvement in residents' overall satisfaction with nursing homes, comparing data across Canada and Italy. Using a structured questionnaire, 681 and 1116 nursing home residents were surveyed in Ontario in 2009 and in Tuscany in 2012, respectively. Fourteen items were common to the surveys, including willingness to recommend (WTR), which was used as the dependent variable and measure of global satisfaction. The other analogous items were entered as covariates in ordinal logistic regression models predicting residents' WTR in each jurisdiction separately...
June 23, 2017: Health Policy
https://www.readbyqxmd.com/read/28686106/neonatal-screening-improves-sickle-cell-disease-clinical-outcome-in-belgium
#5
Phu-Quoc Lê, Alina Ferster, Laurence Dedeken, Christiane Vermylen, Anna Vanderfaeillie, Laurence Rozen, Catherine Heijmans, Sophie Huybrechts, Christine Devalck, Frédéric Cotton, Olivier Ketelslegers, Marie-Françoise Dresse, Jean-François Fils, Béatrice Gulbis
Objectives To compare the outcomes of sickle cell disease patients diagnosed through neonatal screening with those who were not. Methods In an observational multicenter study in Belgium, 167 screened and 93 unscreened sickle cell disease patients were analyzed for a total of 1116 and 958 patient-years of follow-up, respectively. Both groups were compared with propensity score analysis, with patients matched on three covariates (gender, genotype, and central Africa origin). Bonferroni correction was applied for all comparisons...
January 1, 2017: Journal of Medical Screening
https://www.readbyqxmd.com/read/28669625/clinical-risk-factors-predicting-genital-fungal-infections-with-sodium-glucose-cotransporter-2-inhibitor-treatment-the-abcd-nationwide-dapagliflozin-audit
#6
Ken Yan Thong, Mahender Yadagiri, Dennis Joseph Barnes, David Stuart Morris, Tahseen Ahmad Chowdhury, Ling Ling Chuah, Anthony Michael Robinson, Stephen Charles Bain, Karen Ann Adamson, Robert Elford John Ryder
INTRODUCTION: Treatment of type 2 diabetes with sodium-glucose cotransporter 2 (SGLT2) inhibitors may result in genital fungal infections. We investigated possible risk factors for developing such infections among patients treated with the SGLT2 inhibitor dapagliflozin. METHODS: The Association of British Clinical Diabetologists (ABCD) collected data on patients treated with dapagliflozin in routine clinical practice from 59 diabetes centres. We assessed possible associations of patient's age, diabetes duration, body mass index, glycated haemoglobin, renal function, patient sex, ethnicity and prior genital fungal infection, urinary tract infection, urinary incontinence or nocturia, with the occurrence of ≥1 genital fungal infection within 26 weeks of treatment...
June 29, 2017: Primary Care Diabetes
https://www.readbyqxmd.com/read/28669533/effects-of-laparoscopic-cholecystectomy-in-normokinetic-biliary-dyskinesia
#7
Kerent D Pihl, Mark W Jones, Jeffery G Deppen, Troy M Ferguson, Suzanne M Hanses
This is the largest single center retrospective study to date looking at response to laparoscopic cholecystectomy in patients with acalculous biliary disease. A chart review was completed on 1116 patients from 2009 to 2014 who had admitting diagnoses related to acalculous cholecystitis and biliary colic. Four hundred and seventy four patients were available for long term follow up (6 months or longer). Multiple factors were studied as related to cholescintigraphy scans with cholecystokinin administration (HIDA with CCK)...
June 19, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28668308/corrigendum-to-synthetic-fibers-as-microplastics-in-the-marine-environment-a-review-from-textile-perspective-with-a-focus-on-domestic-washings-sci-total-environ-598-2017-1116-1129
#8
Flavia Salvador Cesa, Alexander Turra, Julia Baruque-Ramos
No abstract text is available yet for this article.
June 28, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28645331/circadian-clock-gene-polymorphisms-in-relation-to-sleep-patterns-and-obesity-in-african-americans-findings-from-the-jackson-heart-study
#9
Pia Riestra, Samson Y Gebreab, Ruihua Xu, Rumana J Khan, Amadou Gaye, Adolfo Correa, Nancy Min, Mario Sims, Sharon K Davis
BACKGROUND: Circadian rhythms regulate key biological processes and the dysregulation of the intrinsic clock mechanism affects sleep patterns and obesity onset. The CLOCK (circadian locomotor output cycles protein kaput) gene encodes a core transcription factor of the molecular circadian clock influencing diverse metabolic pathways, including glucose and lipid homeostasis. The primary objective of this study was to evaluate the associations between CLOCK single nucleotide polymorphisms (SNPs) and body mass index (BMI)...
June 23, 2017: BMC Genetics
https://www.readbyqxmd.com/read/28633075/elective-unilateral-nodal-irradiation-in-head-and-neck-squamous-cell-carcinoma-a-paradigm-shift
#10
A Al-Mamgani, M Verheij, M W M van den Brekel
There is a long-standing convention to irradiate the great majority of head and neck squamous cell carcinoma (HNSCC) electively to both sides of the neck, to reduce the theoretically increased risk of contralateral regional failure (cRF). With the currently available diagnostic imaging techniques this treatment paradigm means, in our opinion, an overtreatment in considerable proportion of these patients. From all the published studies (n = 11, with 1116 patients treated in total), the incidence of cRF in patients with oropharyngeal cancer treated to one side of the neck is 2...
June 17, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28617554/the-study-on-specific-umbilical-blood-dc-vaccine-for-beige-nude-mice-loaded-human-colorectal-carcinoma-to-induce-anti-tumor-immunity
#11
Z-X Fu, J-S Han, F Liu, Z-L Zhao, D-B Li, L Shi, J-T Dong, Y Zhou, J-H Cai
OBJECTIVE: This study is to observe the immunosuppression of CD137L transfected umbilical blood Dcs (Dendritic cell) vaccine to tumor development of SCID/ Beige nude mice. MATERIALS AND METHODS: Samples of umbilical blood in the childbirth pregnant women were collected by density gradient centrifugation. Umbilical cord blood dendritic cells (Dcs) were transfected by specific CD137L via LipofectamineTM method and cells were harvested. Meanwhile, the peripheral blood of volunteers was collected to isolate Dcs, the Dcs were cultured for 5 days and hatched with SW-1116 cells antigen...
May 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28567582/serum-and-hair-zinc-levels-in-patients-with-endemic-osteochondropathy-in-china-a-meta-analysis
#12
Xi Wang, Pan Zhang, Yujie Ning, Lei Yang, Fangfang Yu, Xiong Guo
A large number of studies have shown growing interest in the zinc (Zn) levels of serum and hair samples collected from patients with Kashin-Beck disease (KBD), an endemic chronic osteochondral disease. However, inconsistent conclusions regarding the serum and hair Zn levels have been made. The aim of this study is to assess and to explore the change in serum and hair Zn levels among KBD patients. Multiple databases, including PubMed, Web of Science, Chinese National Knowledge Infrastructure (CNKI), Wanfang database and Technology of Chongqing (VIP), were carefully searched for available studies up to January 13, 2017 in this integrated analysis...
May 31, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28533668/rate-of-local-tumor-progression-following-radiofrequency-ablation-of-pathologically-early-hepatocellular-carcinoma
#13
Yoshiteru Hao, Kazushi Numata, Tomohiro Ishii, Hiroyuki Fukuda, Shin Maeda, Masayuki Nakano, Katsuaki Tanaka
AIM: To evaluate whether pathologically early hepatocellular carcinoma (HCC) exhibited local tumor progression after radiofrequency ablation (RFA) less often than typical HCC. METHODS: Fifty pathologically early HCCs [tumor diameter (mm): mean, 15.8; range, 10-23; follow-up days after RFA: median, 1213; range, 216-2137] and 187 typical HCCs [tumor diameter (mm): mean, 15.6; range, 6-30; follow-up days after RFA: median, 1116; range, 190-2328] were enrolled in this retrospective study...
May 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28460530/measuring-the-attractiveness-of-rural-communities-in-accounting-for-differences-of-rural-primary-care-workforce-supply
#14
Matthew R McGrail, Peter M Wingrove, Stephen M Petterson, John S Humphreys, Deborah J Russell, Andrew W Bazemore
INTRODUCTION: Many rural communities continue to experience an undersupply of primary care doctor services. While key professional factors relating to difficulties of recruitment and retention of rural primary care doctors are widely identified, less attention has been given to the role of community and place aspects on supply. Place-related attributes contribute to a community's overall amenity or attractiveness, which arguably influence both rural recruitment and retention relocation decisions of doctors...
April 2017: Rural and Remote Health
https://www.readbyqxmd.com/read/28458660/activity-abundance-and-localization-of-quorum-sensing-receptors-in-vibrio-harveyi
#15
Nicola Lorenz, Jae Yen Shin, Kirsten Jung
Quorum sensing (QS) is a process enabling a bacterial population to communicate via small molecules called autoinducers (AIs). This intercellular communication process allows single cells to synchronize their behavior within a population. The marine bacterium Vibrio harveyi ATCC BAA-1116 channels the information of three AI signals into one QS cascade. Three receptors perceive these AIs, the hybrid histidine kinases LuxN, Lux(P)Q and CqsS, to transduce the information to the histidine phosphotransfer (HPt) protein LuxU via phosphorelay, and finally to the response regulator LuxO...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28418614/efficacy-and-safety-of-low-dose-heparin-in-hemodialysis
#16
Mariana Murea, Gregory B Russell, Pirouz Daeihagh, Anita M Saran, Karan Pandya, Mark Cabrera, John M Burkart, Barry I Freedman
INTRODUCTION: The dose of unfractionated heparin (UFH) administered during hemodialysis (HD) varies widely. This prospective study evaluated the safety and efficacy of UFH dose de-escalation. METHODS: Sixty-six prevalent patients on HD receiving UFH per standard-dose protocol (load dose [LD] 50-75 units/kg, maintenance dose [MD] 500-1000 units/hour) had heparin prescription converted to low-dose protocol (start LD 15 units/kg and MD 500 units/hour; dose adjusted in small increments based on assessments of extracorporeal blood circuit)...
April 18, 2017: Hemodialysis International
https://www.readbyqxmd.com/read/28407309/cadmium-exposure-and-osteoporosis-a-population-based-study-and-benchmark-dose-estimation-in-southern-china
#17
Yingjian Lv, Ping Wang, Rui Huang, Xuxia Liang, Peng Wang, Jianbin Tan, Zihui Chen, Zhongjun Dun, Jing Wang, Qi Jiang, Shixuan Wu, Haituan Ling, Zhixue Li, Xingfen Yang
This study aimed to assess the association between osteoporosis and long-term environmental Cd exposure through diet in southern China. A total of 1116 subjects from a Cd-polluted area and a non-Cd-polluted area were investigated. All subjects met the criteria of having been living in the investigated area for more than 15 years and lived on a subsistence diet of rice and vegetables grown in that area. Besides bone mineral density, the levels of urinary markers of early renal impairment, such as urinary N-acetyl-β-D-glucosaminidase (NAG), α1 -microglobulin, β2 -microglobulin, and urinary albumin, were also determined...
April 13, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28384126/an-automated-method-for-accurate-vessel-segmentation
#18
Xin Yang, Chaoyue Liu, Hung Le Minh, Zhiwei Wang, Aichi Chien, Kwang-Ting Tim Cheng
Vessel segmentation is a critical task for various medical applications, such as diagnosis assistance of diabetic retinopathy, quantification of cerebral aneurysm's growth, and guiding surgery in neurosurgical procedures. Despite technology advances in image segmentation, existing methods still suffer from low accuracy for vessel segmentation in the two challenging while common scenarios in clinical usage: (1) regions with a low signal-to-noise-ratio (SNR), and (2) at vessel boundaries disturbed by adjacent non-vessel pixels...
April 6, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28330106/enhanced-production-of-pectinase-by-aspergillus-terreus-ncft-4269-10-using-banana-peels-as-substrate
#19
Bijay Kumar Sethi, Prativa Kumari Nanda, Santilata Sahoo
Aspergillus terreus NCFT4269.10 was implemented in solid-state (SSF) and liquid static surface fermentation (LSSF) for biosynthesis of pectinase. Amongst various substrates, like, mustard oil cake, neem oil cake, groundnut oil cake, black gram peels, green gram peels, chickling vetch peels/grass pea peels wheat bran, pearl millet residues, finger millet waste, broken rice, banana peels (BP), apple pomace (AP) and orange peels, banana peel (Musa paradisiaca L.; Family: Musaceae) was most suitable for pectinase biosynthesis (LSSF: 400 ± 21...
June 2016: 3 Biotech
https://www.readbyqxmd.com/read/28320025/-the-influence-of-caseload-on-continuous-treatment-with%C3%A2-antidementia-drugs
#20
Jens Bohlken, Karel Kostev
Objective The goal of this study is to investigate the impact of the number of dementia cases in general and specialist practices on the continuity of treatment with antidementia drugs. Methodology Period between 2004 and 2013: 1116 general practices, 200 specialist practices, 37 178 dementia cases; observation period: 36 months. Practice groups with 1 - 9, 10 - 20, 21-s49, and ≥ 50 dementia cases. Results The treatment continuity is higher in practices with an average of 150 dementia cases than in practices with five dementia cases (73...
March 2017: Fortschritte der Neurologie-Psychiatrie
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